#=GF ID STI1-HOP_DP
#=GF AC PF17830.7
#=GF DE STI1/HOP, DP domain
#=GF PI STI1;
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE ECOD:EUF00994
#=GF GA 29.10 29.10;
#=GF TC 29.10 29.10;
#=GF NC 29.00 29.00;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 8 -Z 90746521 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 22888115
#=GF RT Solution structure of the C-terminal NP-repeat domain of Tic40,
#=GF RT a co-chaperone during protein import into chloroplasts.
#=GF RA Kao YF, Lou YC, Yeh YH, Hsiao CD, Chen C;
#=GF RL J Biochem. 2012;152:443-451.
#=GF RN [2]
#=GF RM 22227520
#=GF RT The architecture of functional modules in the Hsp90 co-chaperone
#=GF RT Sti1/Hop.
#=GF RA Schmid AB, Lagleder S, Grawert MA, Rohl A, Hagn F, Wandinger SK,
#=GF RA Cox MB, Demmer O, Richter K, Groll M, Kessler H, Buchner J;
#=GF RL EMBO J. 2012;31:1506-1517.
#=GF RN [3]
#=GF RM 31525467
#=GF RT Structural studies of the Hsp70/Hsp90 organizing protein of
#=GF RT Plasmodium falciparum and its modulation of Hsp70 and Hsp90
#=GF RT ATPase activities.
#=GF RA Silva NSM, Bertolino-Reis DE, Dores-Silva PR, Anneta FB,
#=GF RA Seraphim TV, Barbosa LRS, Borges JC;
#=GF RL Biochim Biophys Acta Proteins Proteom. 2020;1868:140282.
#=GF DR INTERPRO; IPR041243;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This entry corresponds to the STI1/HOP aspartate/proline-rich
#=GF CC (DP) domain that is found in two copies in the Sti1 protein and
#=GF CC are referred to as DP1 and DP2 [1,2,3]. STI1/HOP proteins are
#=GF CC cochaperones that belong to the foldosome, a system consisting
#=GF CC in Hsp70 and Hsp90 chaperones. STI1/HOP acts as an adapter
#=GF CC protein capable of transferring client proteins from the first
#=GF CC to the second molecular chaperone [3]. This domain (and
#=GF CC specifically DP2 from STI1) is involved in client activation
#=GF CC [2,3].
#=GF SQ 8385
#=GS A0A8S1CC69_9INSE/106-169 AC A0A8S1CC69.1
#=GS A0A5D2YJF7_GOSMU/253-306 AC A0A5D2YJF7.1
#=GS A0A0C7MUR2_9SACH/525-579 AC A0A0C7MUR2.1
#=GS A0A4U0UW96_9PEZI/522-570 AC A0A4U0UW96.1
#=GS A0AAF0UDY9_SOLVR/356-410 AC A0AAF0UDY9.1
#=GS A0A9W9F9W9_9EURO/511-565 AC A0A9W9F9W9.1
#=GS A0A9P8BK18_9AGAM/525-579 AC A0A9P8BK18.1
#=GS A0A8C7MU62_ONCKI/470-524 AC A0A8C7MU62.1
#=GS A0A8C9MRJ7_SERCA/268-320 AC A0A8C9MRJ7.1
#=GS A0A7L0X0F7_TYRSA/127-179 AC A0A7L0X0F7.1
#=GS A0A7J9ARZ2_9ROSI/138-191 AC A0A7J9ARZ2.1
#=GS A0A0A1TFS8_9HYPO/141-195 AC A0A0A1TFS8.1
#=GS A0A2I2Z5I5_GORGO/529-583 AC A0A2I2Z5I5.1
#=GS A0AAD7RNX5_9TELE/305-357 AC A0AAD7RNX5.1
#=GS A0AAE8M1B2_9HYPO/520-574 AC A0AAE8M1B2.1
#=GS A0A6J3L3F7_9HYME/128-182 AC A0A6J3L3F7.1
#=GS A0A815BZN9_9BILA/26-79 AC A0A815BZN9.1
#=GS A0A2K5IGU3_COLAP/275-324 AC A0A2K5IGU3.1
#=GS A0A9W9D488_9PLEO/140-194 AC A0A9W9D488.1
#=GS A0A668ANG4_9TELE/481-535 AC A0A668ANG4.1
#=GS W1NHR4_AMBTC/135-189 AC W1NHR4.1
#=GS A0A1W0A8C1_9STRA/497-551 AC A0A1W0A8C1.1
#=GS A0A078IAN1_BRANA/131-185 AC A0A078IAN1.1
#=GS A0A1U7X1I3_NICSY/353-404 AC A0A1U7X1I3.1
#=GS A0A267G9A0_9PLAT/19-73 AC A0A267G9A0.1
#=GS A0A9P6N195_9FUNG/133-187 AC A0A9P6N195.1
#=GS A0A9P9WK50_9PEZI/526-580 AC A0A9P9WK50.1
#=GS A0A9X0DMV8_9HELO/140-194 AC A0A9X0DMV8.1
#=GS A0A2K5N0J7_CERAT/130-184 AC A0A2K5N0J7.1
#=GS A0A6P5XDB9_DURZI/164-217 AC A0A6P5XDB9.1
#=GS A0A8K1G5T5_9PASS/300-353 AC A0A8K1G5T5.1
#=GS HSOP3_ARATH/131-185 AC Q9STH1.1
#=GS A0A8X7MNG1_9BASI/175-229 AC A0A8X7MNG1.1
#=GS A0A0D2BK78_9EURO/140-194 AC A0A0D2BK78.1
#=GS A0A1A8W2Q9_PLAOA/498-552 AC A0A1A8W2Q9.1
#=GS A0A0D2VGU7_CAPO3/533-587 AC A0A0D2VGU7.1
#=GS A0A9Q0T7U8_SALVM/135-189 AC A0A9Q0T7U8.1
#=GS B9RBP6_RICCO/133-187 AC B9RBP6.1
#=GS A0A395NNH1_TRIAR/141-195 AC A0A395NNH1.1
#=GS E0VDJ6_PEDHC/80-127 AC E0VDJ6.1
#=GS A0AA41SMT0_PAPNU/249-302 AC A0AA41SMT0.1
#=GS A0A2W1BB33_HELAM/479-533 AC A0A2W1BB33.1
#=GS A0A0D3ASS9_BRAOL/506-560 AC A0A0D3ASS9.1
#=GS A0A852B5U9_9CORV/246-299 AC A0A852B5U9.1
#=GS A0A9J5WK89_SOLCO/342-395 AC A0A9J5WK89.1
#=GS A0A6G1E6D8_9ORYZ/341-392 AC A0A6G1E6D8.1
#=GS A0AAJ0ALX8_9PEZI/140-194 AC A0AAJ0ALX8.1
#=GS A0A7L2EXN3_QUIME/266-319 AC A0A7L2EXN3.1
#=GS A0A7J9LQ05_GOSSC/323-374 AC A0A7J9LQ05.1
#=GS A0A507FHY4_9FUNG/1194-1248 AC A0A507FHY4.1
#=GS A0A9P3BW64_ASPVI/518-572 AC A0A9P3BW64.1
#=GS A0A8S4MQI4_BRALA/140-194 AC A0A8S4MQI4.1
#=GS A0A6G1D1J9_9ORYZ/138-191 AC A0A6G1D1J9.1
#=GS A0A8C1CNU8_CYPCA/301-354 AC A0A8C1CNU8.2
#=GS A0A1Y2I6V1_9FUNG/132-186 AC A0A1Y2I6V1.1
#=GS A0AAF0ZN89_SOLVR/518-572 AC A0AAF0ZN89.1
#=GS A0A9P5QKR8_9FUNG/513-567 AC A0A9P5QKR8.1
#=GS A0A452IMI2_9SAUR/22-76 AC A0A452IMI2.1
#=GS A0A922IAV1_DERFA/264-318 AC A0A922IAV1.1
#=GS A0A672T4D3_SINGR/271-322 AC A0A672T4D3.1
#=GS A0A8H4Y5Y3_9HYPO/135-193 AC A0A8H4Y5Y3.1
#=GS A0A9W7XJV8_9FUNG/138-192 AC A0A9W7XJV8.1
#=GS A0A8V0YHQ6_CHICK/304-357 AC A0A8V0YHQ6.1
#=GS A0A5N6DF75_ASPPA/517-571 AC A0A5N6DF75.1
#=GS A0A804L3U5_MUSAM/514-568 AC A0A804L3U5.1
#=GS A0A6P3QN06_PTEVA/130-184 AC A0A6P3QN06.1
#=GS A0A9W7Y0E2_9FUNG/138-192 AC A0A9W7Y0E2.1
#=GS A0A6J1WET4_GALME/300-354 AC A0A6J1WET4.1
#=GS A0A8U0QAA0_SALNM/336-388 AC A0A8U0QAA0.1
#=GS A0A5N5WZB8_9EURO/140-194 AC A0A5N5WZB8.1
#=GS A0A485L5C6_9STRA/27-80 AC A0A485L5C6.1
#=GS G5C934_HETGA/198-250 AC G5C934.1
#=GS A0AA39QVC6_9LECA/525-579 AC A0AA39QVC6.1
#=GS A0A8I3Q158_CANLF/185-238 AC A0A8I3Q158.1
#=GS A0A7L3I6T2_9PASS/300-353 AC A0A7L3I6T2.1
#=GS A9PEQ3_POPTR/135-189 AC A9PEQ3.1
#=GS A0A8K0E147_9ROSA/151-199 AC A0A8K0E147.1
#=GS A0A7K6D4E9_9PASS/300-353 AC A0A7K6D4E9.1
#=GS A0A7R5KXN6_9PASS/467-521 AC A0A7R5KXN6.1
#=GS A0A8J4U1B7_CLAMG/276-329 AC A0A8J4U1B7.1
#=GS A0A0C4EXF1_PUCT1/242-295 AC A0A0C4EXF1.1
#=GS A0A093JA08_STRCA/281-334 AC A0A093JA08.1
#=GS A0A445AM53_ARAHY/370-423 AC A0A445AM53.1
#=GS A0A8H3ITH4_9LECA/520-574 AC A0A8H3ITH4.1
#=GS A0A0E0ETS0_9ORYZ/125-178 AC A0A0E0ETS0.1
#=GS A0A834LIQ0_RHOSS/347-401 AC A0A834LIQ0.1
#=GS A0A2K3NU59_TRIPR/143-191 AC A0A2K3NU59.1
#=GS H2YCW8_CIOSA/131-185 AC H2YCW8.1
#=GS A8WXL9_CAEBR/259-313 AC A8WXL9.1
#=GS A0A0P7THN6_SCLFO/293-344 AC A0A0P7THN6.1
#=GS A0A3Q3FT80_KRYMA/481-535 AC A0A3Q3FT80.1
#=GS A4HTP4_LEIIN/131-185 AC A4HTP4.1
#=GS A0A2K6RG40_RHIRO/200-249 AC A0A2K6RG40.1
#=GS A0A9R1T184_9HYME/262-313 AC A0A9R1T184.1
#=GS A0A2G5UT72_9PELO/101-153 AC A0A2G5UT72.1
#=GS A0A6I9RX13_ELAGV/136-190 AC A0A6I9RX13.1
#=GS A0A199VC29_ANACO/323-374 AC A0A199VC29.1
#=GS A0A9P0C3J6_9NEOP/4-60 AC A0A9P0C3J6.1
#=GS A0A8S9ZB98_9BILA/306-346 AC A0A8S9ZB98.1
#=GS A0A8C5R0V3_9ANUR/481-535 AC A0A8C5R0V3.1
#=GS L1IWR8_GUITC/2-60 AC L1IWR8.1
#=GS L8FZI1_PSED2/512-565 AC L8FZI1.1
#=GS A0A5N5N0E2_9ROSI/168-219 AC A0A5N5N0E2.1
#=GS A0A804P5Q6_MAIZE/355-406 AC A0A804P5Q6.1
#=GS E4UP15_ARTGP/140-194 AC E4UP15.1
#=GS A0A7J0G568_9ERIC/1-52 AC A0A7J0G568.1
#=GS A0A2G9V0J5_TELCI/62-112 AC A0A2G9V0J5.1
#=GS V4L767_EUTSA/136-190 AC V4L767.1
#=GS M5E855_MALS4/143-197 AC M5E855.1
#=GS A0A0G2HJQ5_9PEZI/139-195 AC A0A0G2HJQ5.1
#=GS A0A9P8WIX0_9HYPO/527-580 AC A0A9P8WIX0.1
#=GS A0A388KKL5_CHABU/452-506 AC A0A388KKL5.1
#=GS A0A8C6HKG3_MUSSI/482-536 AC A0A8C6HKG3.1
#=GS A0A6J1Y9R1_ACIJB/130-184 AC A0A6J1Y9R1.1
#=GS A0A1D2VR72_9ASCO/543-597 AC A0A1D2VR72.1
#=GS A0AAD3Y9S8_9TREE/521-575 AC A0AAD3Y9S8.1
#=GS A0A8C8CNW5_ONCTS/461-515 AC A0A8C8CNW5.1
#=GS A3FQ73_CRYPI/265-319 AC A3FQ73.1
#=GS A0A811ZMV7_NYCPR/102-156 AC A0A811ZMV7.1
#=GS A0A8C1CQH5_CYPCA/300-353 AC A0A8C1CQH5.2
#=GS A0A2R6S3K4_9APHY/102-157 AC A0A2R6S3K4.1
#=GS F7EPZ6_ORNAN/150-204 AC F7EPZ6.3
#=GS A0A8X7NVX4_BRACI/142-196 AC A0A8X7NVX4.1
#=GS A0A8X8ZTF7_SALSN/137-191 AC A0A8X8ZTF7.1
#=GS R0G5Z2_9BRAS/175-228 AC R0G5Z2.1
#=GS A0A8K0S7K5_9HYPO/520-574 AC A0A8K0S7K5.1
#=GS K3VYG4_FUSPC/139-193 AC K3VYG4.1
#=GS A0A6A3CJN3_HIBSY/91-143 AC A0A6A3CJN3.1
#=GS A0AAD6NEY4_PENCN/140-194 AC A0AAD6NEY4.1
#=GS B2AAQ5_PODAN/141-195 AC B2AAQ5.1
#=GS A0AAY4DW51_9TELE/132-186 AC A0AAY4DW51.1
#=GS A0A4Y2GDU4_ARAVE/306-360 AC A0A4Y2GDU4.1
#=GS W9IIP9_FUSOX/21-75 AC W9IIP9.1
#=GS A0A5N6JJH0_9EURO/517-571 AC A0A5N6JJH0.1
#=GS A0A6J1JHX2_CUCMA/353-406 AC A0A6J1JHX2.1
#=GS A0A811PED5_9POAL/518-571 AC A0A811PED5.1
#=GS A0A8T0VNZ3_PANVG/119-172 AC A0A8T0VNZ3.1
#=GS A0A834YGA0_TETSI/128-182 AC A0A834YGA0.1
#=GS A0A9J8CDR9_CYPCA/496-550 AC A0A9J8CDR9.1
#=GS A0A7I8L1I0_SPIIN/516-569 AC A0A7I8L1I0.1
#=GS A0A2K5CWN9_AOTNA/130-184 AC A0A2K5CWN9.1
#=GS A0A022R4I3_ERYGU/13-66 AC A0A022R4I3.1
#=GS A0A673A566_9TELE/130-184 AC A0A673A566.1
#=GS A0A8I3P514_CANLF/310-363 AC A0A8I3P514.1
#=GS A0A8C5G7W6_GOUWI/132-186 AC A0A8C5G7W6.1
#=GS HSOP_WHEAT/520-574 AC F8RP11.1
#=GS A0A9D3SNP2_9TELE/334-387 AC A0A9D3SNP2.1
#=GS A0A8B8YHP7_BALMU/341-394 AC A0A8B8YHP7.1
#=GS A0A834U8Q8_VESPE/476-530 AC A0A834U8Q8.1
#=GS A0A3L6PW01_PANMI/276-329 AC A0A3L6PW01.1
#=GS A0A1Y2M9H4_EPING/520-574 AC A0A1Y2M9H4.1
#=GS A0AAD8H815_9APIA/373-426 AC A0AAD8H815.1
#=GS A0A8C7MTT6_ONCKI/479-533 AC A0A8C7MTT6.1
#=GS K0KTQ1_WICCF/527-581 AC K0KTQ1.1
#=GS A0A8C9Q594_SPEDA/298-351 AC A0A8C9Q594.1
#=GS G0V573_NAUCA/559-613 AC G0V573.1
#=GS A0A9W9D488_9PLEO/521-575 AC A0A9W9D488.1
#=GS A0A1U7VEK0_NICSY/139-193 AC A0A1U7VEK0.1
#=GS A2QYC9_ASPNC/518-572 AC A2QYC9.1
#=GS A0A8K0UXW8_9AGAR/136-191 AC A0A8K0UXW8.1
#=GS A0AAY4DTT5_9TELE/481-535 AC A0AAY4DTT5.1
#=GS A0A8C9M216_PANTA/177-231 AC A0A8C9M216.1
#=GS W2Y8M6_PHYNI/135-189 AC W2Y8M6.1
#=GS A0A0D2XB23_FUSOF/139-193 AC A0A0D2XB23.1
#=GS A0A1S3CIG9_CUCME/356-409 AC A0A1S3CIG9.1
#=GS A0A093XF89_9PEZI/141-195 AC A0A093XF89.1
#=GS A0A9C6TV12_FRAOC/316-369 AC A0A9C6TV12.1
#=GS A0A7L4D3H3_9AVES/268-321 AC A0A7L4D3H3.1
#=GS C1E0Z1_MICCC/590-643 AC C1E0Z1.1
#=GS A0A6J1VU92_9SAUR/490-544 AC A0A6J1VU92.1
#=GS A0A2K5BZC9_AOTNA/295-348 AC A0A2K5BZC9.1
#=GS A0A026WY50_OOCBI/480-534 AC A0A026WY50.1
#=GS A0A6J0J826_9PASS/157-211 AC A0A6J0J826.1
#=GS A0AB34JXE8_PRYPA/334-388 AC A0AB34JXE8.1
#=GS A0A0L1I6R2_PLAFA/503-557 AC A0A0L1I6R2.1
#=GS A0D1I8_PARTE/106-161 AC A0D1I8.1
#=GS A0A9P7UXR1_9AGAR/512-566 AC A0A9P7UXR1.1
#=GS A0A7R9QFK4_9ACAR/293-347 AC A0A7R9QFK4.1
#=GS A0A3M7NJL8_9EURO/469-523 AC A0A3M7NJL8.1
#=GS A0A068TMH4_COFCA/168-220 AC A0A068TMH4.1
#=GS A0A1S3BJ11_CUCME/157-210 AC A0A1S3BJ11.1
#=GS A0A6P5S3S5_PRUAV/136-190 AC A0A6P5S3S5.1
#=GS A0A6P8BEV0_PYRGI/143-197 AC A0A6P8BEV0.1
#=GS A0A7J7CUS3_TRIWF/378-431 AC A0A7J7CUS3.1
#=GS A0A395SR81_9HYPO/139-193 AC A0A395SR81.1
#=GS A0A815G639_9BILA/497-551 AC A0A815G639.1
#=GS A0A9D4UBV7_ADICA/138-192 AC A0A9D4UBV7.1
#=GS A0A6A1Q2X9_BALPH/17-64 AC A0A6A1Q2X9.1
#=GS A0AAE1QR67_9SOLA/146-196 AC A0AAE1QR67.1
#=GS A0A199VNJ2_ANACO/135-185 AC A0A199VNJ2.1
#=GS A0A8S1T5I6_PAROT/137-191 AC A0A8S1T5I6.1
#=GS A0AAE0XJB5_9PEZI/141-195 AC A0AAE0XJB5.1
#=GS A0A485K9J0_9STRA/506-560 AC A0A485K9J0.1
#=GS H2ND10_PONAB/482-536 AC H2ND10.2
#=GS A0A9P3UJK5_LYOSH/132-186 AC A0A9P3UJK5.1
#=GS A0A834GTE1_RHOSS/378-432 AC A0A834GTE1.1
#=GS A0A5B6WMI1_9ROSI/107-157 AC A0A5B6WMI1.1
#=GS A0A250XZG6_CASCN/310-363 AC A0A250XZG6.1
#=GS A0A1G4IV50_9SACH/523-577 AC A0A1G4IV50.1
#=GS A0A385X5W0_FUSC4/139-193 AC A0A385X5W0.1
#=GS A0A250WTB2_9CHLO/427-481 AC A0A250WTB2.1
#=GS A0A060SIW8_PYCCI/519-573 AC A0A060SIW8.1
#=GS A0AAJ0BGG4_9PEZI/142-196 AC A0AAJ0BGG4.1
#=GS A0A3L6TK86_PANMI/147-200 AC A0A3L6TK86.1
#=GS A0A512UN21_9ASCO/136-191 AC A0A512UN21.1
#=GS A0A158NUQ5_ATTCE/293-344 AC A0A158NUQ5.1
#=GS A0A8T1WRG5_9STRA/150-205 AC A0A8T1WRG5.1
#=GS A0A3P8XPM0_ESOLU/327-379 AC A0A3P8XPM0.3
#=GS A0A672HBQ3_SALFA/238-290 AC A0A672HBQ3.1
#=GS A0A4S4EE86_CAMSI/513-567 AC A0A4S4EE86.1
#=GS A0A674AVR1_SALTR/130-184 AC A0A674AVR1.1
#=GS W9VV56_9EURO/137-191 AC W9VV56.1
#=GS A0AA40LJ59_CNENI/368-422 AC A0AA40LJ59.1
#=GS A0A8T2UNJ0_CERRI/1-42 AC A0A8T2UNJ0.1
#=GS A0A369GSJ3_9HYPO/521-575 AC A0A369GSJ3.1
#=GS A0A091PMV6_LEPDC/273-326 AC A0A091PMV6.1
#=GS A0AA39GQZ4_SARSR/513-567 AC A0AA39GQZ4.1
#=GS A0A8S1IWG1_9CHLO/127-181 AC A0A8S1IWG1.1
#=GS A0AA39HSQ4_9BILA/259-312 AC A0AA39HSQ4.1
#=GS A0A4Z1I4A4_9HELO/525-579 AC A0A4Z1I4A4.1
#=GS A0A6P6CVN4_PTEVA/288-341 AC A0A6P6CVN4.1
#=GS A0AAD8YXU7_9TELE/481-525 AC A0AAD8YXU7.1
#=GS A0A2K6JWX5_RHIBE/133-187 AC A0A2K6JWX5.1
#=GS A0A9W7XJV8_9FUNG/518-572 AC A0A9W7XJV8.1
#=GS A0A8C7XBB1_9TELE/130-184 AC A0A8C7XBB1.1
#=GS A0A8H8QXQ5_9HELO/144-198 AC A0A8H8QXQ5.1
#=GS A0A2K6KUT8_RHIBE/382-427 AC A0A2K6KUT8.1
#=GS A0A4Y7TNU5_COPMI/1-52 AC A0A4Y7TNU5.1
#=GS A0A8C4AV84_9TELE/303-356 AC A0A8C4AV84.1
#=GS A0A067LI29_JATCU/147-200 AC A0A067LI29.1
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#=GC seq_cons .............................phhp+...lhs.DPc........l.ts.hh....p....DPsh........ht......h...........Lp.......p.........hpp....sP..........s...sl...p.cah..psP..cl...h...p...h...l...scLh................
//
