#=GF ID STING_LBD
#=GF AC PF15009.13
#=GF DE STING ligand-binding domain
#=GF PI TMEM173;
#=GF AU Eberhardt R;0000-0001-6152-1369
#=GF AU Chuguransky S;0000-0002-0520-0736
#=GF SE Jackhmmer:Q86WV6
#=GF GA 27.00 27.00;
#=GF TC 27.90 27.40;
#=GF NC 26.50 26.80;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 90746521 -E 1000 --cpu 8 HMM pfamseq
#=GF TP Domain
#=GF CL CL0709
#=GF RN [1]
#=GF RM 18724357
#=GF RT STING is an endoplasmic reticulum adaptor that facilitates
#=GF RT innate immune signalling.
#=GF RA Ishikawa H, Barber GN;
#=GF RL Nature. 2008;455:674-678.
#=GF RN [2]
#=GF RM 19776740
#=GF RT STING regulates intracellular DNA-mediated, type I
#=GF RT interferon-dependent innate immunity.
#=GF RA Ishikawa H, Ma Z, Barber GN;
#=GF RL Nature. 2009;461:788-792.
#=GF RN [3]
#=GF RM 18818105
#=GF RT The adaptor protein MITA links virus-sensing receptors to IRF3
#=GF RT transcription factor activation.
#=GF RA Zhong B, Yang Y, Li S, Wang YY, Li Y, Diao F, Lei C, He X, Zhang
#=GF RA L, Tien P, Shu HB;
#=GF RL Immunity. 2008;29:538-550.
#=GF RN [4]
#=GF RM 19433799
#=GF RT ERIS, an endoplasmic reticulum IFN stimulator, activates innate
#=GF RT immune signaling through dimerization.
#=GF RA Sun W, Li Y, Chen L, Chen H, You F, Zhou X, Zhou Y, Zhai Z, Chen
#=GF RA D, Jiang Z;
#=GF RL Proc Natl Acad Sci U S A. 2009;106:8653-8658.
#=GF RN [5]
#=GF RM 22728660
#=GF RT Crystal structures of STING protein reveal basis for recognition
#=GF RT of cyclic di-GMP.
#=GF RA Shang G, Zhu D, Li N, Zhang J, Zhu C, Lu D, Liu C, Yu Q, Zhao Y,
#=GF RA Xu S, Gu L;
#=GF RL Nat Struct Mol Biol. 2012;19:725-727.
#=GF RN [6]
#=GF RM 35388221
#=GF RT Activation of STING by targeting a pocket in the transmembrane
#=GF RT domain.
#=GF RA Lu D, Shang G, Li J, Lu Y, Bai XC, Zhang X;
#=GF RL Nature. 2022;604:557-562.
#=GF DR INTERPRO; IPR055432;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC Transmembrane protein 173, also known as stimulator of
#=GF CC interferon genes protein (STING), is a transmembrane adaptor
#=GF CC protein which is involved in innate immune signalling processes.
#=GF CC It induces expression of type I interferons (IFN-alpha and
#=GF CC IFN-beta) via the NF-kappa-B and IRF3, pathways in response to
#=GF CC non-self cytosolic RNA and dsDNA [1-4]. It consists of an
#=GF CC N-terminal transmembrane (TM) and a C-terminal ligand-binding
#=GF CC (LBD) domains. This entry represents the LBD which binds to
#=GF CC c-di-GMP [5,6]. Cyclic dinucleotides induce a conformational
#=GF CC change to the STING LBD, leading to high-order oligomerization
#=GF CC of STING that is essential for triggering the downstream
#=GF CC signalling pathways [6].
#=GF SQ 1237
#=GS A0A9P9YGE4_9MUSC/975-1044 AC A0A9P9YGE4.1
#=GS B4QHR9_DROSI/122-308 AC B4QHR9.1
#=GS STNG5_STYPI/106-291 AC A0A2B4SJZ1.1
#=GS A0A850XUU3_AEGCA/12-195 AC A0A850XUU3.1
#=GS A0A7L4AI83_9AVES/12-195 AC A0A7L4AI83.1
#=GS A0A7M7H561_APIME/70-264 AC A0A7M7H561.1
#=GS A0A7L4HWG3_SCOUM/12-195 AC A0A7L4HWG3.1
#=GS A0A7K7ZTM4_9PASE/12-195 AC A0A7K7ZTM4.1
#=GS A0A851XCF1_EOLRO/12-195 AC A0A851XCF1.1
#=GS A0A8W8ILH9_MAGGI/170-350 AC A0A8W8ILH9.1
#=GS A0AAD9KCN1_9ANNE/163-290 AC A0AAD9KCN1.1
#=GS A0A672HCG5_SALFA/154-339 AC A0A672HCG5.1
#=GS A0A9Q1IT36_SYNKA/178-367 AC A0A9Q1IT36.1
#=GS A0A8B9VMU3_9AVES/8-111 AC A0A8B9VMU3.1
#=GS B4HT52_DROSE/122-308 AC B4HT52.1
#=GS STING_HUMAN/154-337 AC Q86WV6.1
#=GS A0A7L4KRB6_9CORV/12-173 AC A0A7L4KRB6.1
#=GS A0A8W8JPP1_MAGGI/161-348 AC A0A8W8JPP1.1
#=GS A0A6P6NA04_CARAU/151-329 AC A0A6P6NA04.1
#=GS A0A8J5R130_9HYME/179-274 AC A0A8J5R130.1
#=GS A0A6J1SMP7_FRAOC/167-369 AC A0A6J1SMP7.2
#=GS A0A913XQ24_EXADI/168-348 AC A0A913XQ24.1
#=GS A0A210QVA3_MIZYE/160-340 AC A0A210QVA3.1
#=GS A0A8B8WYF9_BALMU/265-448 AC A0A8B8WYF9.1
#=GS A0A3Q2UT12_HAPBU/157-342 AC A0A3Q2UT12.1
#=GS A0A0T6BH49_9SCAR/1-186 AC A0A0T6BH49.1
#=GS A0A8C4UFF0_FALTI/155-326 AC A0A8C4UFF0.1
#=GS A0A087R3K5_APTFO/151-334 AC A0A087R3K5.1
#=GS A0A7K5DB45_9TYRA/12-195 AC A0A7K5DB45.1
#=GS A0A7L2DRP9_ANTMN/12-195 AC A0A7L2DRP9.1
#=GS A0A7K6UKB1_9AVES/12-194 AC A0A7K6UKB1.1
#=GS A0A7K7M8R1_9PASS/12-195 AC A0A7K7M8R1.1
#=GS A0A7K5E2B7_POLCE/12-195 AC A0A7K5E2B7.1
#=GS A0AA88N6J2_CHASR/156-341 AC A0AA88N6J2.1
#=GS A0A835L9Y4_SPOEX/424-618 AC A0A835L9Y4.1
#=GS M3VX62_FELCA/153-336 AC M3VX62.1
#=GS A0A8T3DPF9_9TELE/153-339 AC A0A8T3DPF9.1
#=GS A0A851MDR4_9DEND/12-195 AC A0A851MDR4.1
#=GS STING_BOVIN/154-337 AC Q2KI99.1
#=GS A0A674BS51_SALTR/153-337 AC A0A674BS51.1
#=GS A0A8B7UVI3_CASCN/154-334 AC A0A8B7UVI3.1
#=GS A0A814ETP7_ADIRI/590-800 AC A0A814ETP7.1
#=GS A0A2I2Y8P8_GORGO/154-261 AC A0A2I2Y8P8.1
#=GS A0A8B9DYF5_ANSCY/157-340 AC A0A8B9DYF5.1
#=GS A0A0M4EWG0_DROBS/122-301 AC A0A0M4EWG0.1
#=GS A0AAD4PGN4_9MUSC/127-293 AC A0AAD4PGN4.1
#=GS A0A6A4WTS3_AMPAM/147-336 AC A0A6A4WTS3.1
#=GS A0A7D9EGP6_PARCT/208-390 AC A0A7D9EGP6.1
#=GS A0A8J1J6F3_XENTR/162-348 AC A0A8J1J6F3.1
#=GS A0AAE0S3X4_9BIVA/493-696 AC A0AAE0S3X4.1
#=GS A0A7K7D6Y0_PHEME/12-195 AC A0A7K7D6Y0.1
#=GS A0A7L2PYV0_9PASS/12-195 AC A0A7L2PYV0.1
#=GS A0A8C0H4E8_CHEAB/155-338 AC A0A8C0H4E8.1
#=GS A0A2K6ES67_PROCO/153-333 AC A0A2K6ES67.1
#=GS A0A8C5UAR1_9PASS/155-338 AC A0A8C5UAR1.1
#=GS A0A8C8WH55_PANLE/153-258 AC A0A8C8WH55.1
#=GS A0A8C9E502_PHOSS/35-218 AC A0A8C9E502.1
#=GS A0AAA9S3J6_BOVIN/240-327 AC A0AAA9S3J6.1
#=GS A0A9W2Y398_BETSP/163-348 AC A0A9W2Y398.1
#=GS A0A087X376_POEFO/157-340 AC A0A087X376.1
#=GS A0A7D9LMN8_PARCT/111-295 AC A0A7D9LMN8.1
#=GS A0A6J1Q2G8_9HYME/216-410 AC A0A6J1Q2G8.1
#=GS A0A2K6RUF9_RHIRO/154-337 AC A0A2K6RUF9.1
#=GS A0A7K9CAX9_9PICI/12-195 AC A0A7K9CAX9.1
#=GS STING_CHICK/159-342 AC E1C7U0.2
#=GS A0A667GMS5_LYNCA/153-336 AC A0A667GMS5.1
#=GS A0A5N5NFG2_PANHP/165-346 AC A0A5N5NFG2.1
#=GS A0A8B8AB81_CRAVI/245-433 AC A0A8B8AB81.1
#=GS A0A8J2HH30_COTCN/158-344 AC A0A8J2HH30.1
#=GS A0A7L0EMG9_TROML/12-194 AC A0A7L0EMG9.1
#=GS A0A093JAH7_EURHL/81-263 AC A0A093JAH7.1
#=GS A0A6P8SW73_GYMAC/156-338 AC A0A6P8SW73.1
#=GS A0A851DAZ0_TODME/12-195 AC A0A851DAZ0.1
#=GS A0A8T0EIP7_ARGBR/157-321 AC A0A8T0EIP7.1
#=GS A0AA97L3V4_EUBMA/157-340 AC A0AA97L3V4.1
#=GS A0AA88MB59_TACVA/148-328 AC A0AA88MB59.1
#=GS A0A8C7D1F4_ONCKI/153-337 AC A0A8C7D1F4.1
#=GS A0AAD9R3K1_ACRCE/449-627 AC A0AAD9R3K1.1
#=GS A0A8W8IKV3_MAGGI/190-329 AC A0A8W8IKV3.1
#=GS A0A9J7E6Y7_SPOLT/218-343 AC A0A9J7E6Y7.1
#=GS A0A8B8ESP3_CRAVI/170-350 AC A0A8B8ESP3.1
#=GS A0A9D4D8R4_DREPO/179-359 AC A0A9D4D8R4.1
#=GS A0A3P8SIZ7_AMPPE/157-342 AC A0A3P8SIZ7.1
#=GS L5LCU6_MYODS/213-396 AC L5LCU6.1
#=GS A0AAE0VZ47_9BIVA/501-679 AC A0AAE0VZ47.1
#=GS A0A6I8UW46_DROPS/144-330 AC A0A6I8UW46.1
#=GS A0A8B6CD74_MYTGA/150-333 AC A0A8B6CD74.1
#=GS S7NHZ9_MYOBR/35-218 AC S7NHZ9.1
#=GS A0A835NSR5_9PASS/157-340 AC A0A835NSR5.1
#=GS A0A3P9N9Q2_POERE/243-426 AC A0A3P9N9Q2.1
#=GS A0A9D4D6N3_DREPO/435-636 AC A0A9D4D6N3.1
#=GS A0A093BB29_CHAPE/128-320 AC A0A093BB29.1
#=GS A0A9W3FN76_CAMBA/35-218 AC A0A9W3FN76.1
#=GS A0A9D4N2T3_DREPO/312-492 AC A0A9D4N2T3.1
#=GS A0A7L4C8A4_9AVES/12-195 AC A0A7L4C8A4.1
#=GS A0A4C1TVE8_EUMVA/26-195 AC A0A4C1TVE8.1
#=GS A0A2J7PDI7_9NEOP/178-382 AC A0A2J7PDI7.1
#=GS A0A3Q2HNT1_HORSE/212-379 AC A0A3Q2HNT1.2
#=GS A0A341C140_NEOAA/82-265 AC A0A341C140.1
#=GS A0A6G1ARW0_CROCR/154-336 AC A0A6G1ARW0.1
#=GS A0A8B6HPW4_MYTGA/1-117 AC A0A8B6HPW4.1
#=GS A0A7K8FST6_9CORV/12-195 AC A0A7K8FST6.1
#=GS STING_DANRE/151-328 AC E7F4N7.1
#=GS A0A9X9MAB0_GULGU/154-337 AC A0A9X9MAB0.1
#=GS A0A094KEQ9_PODCR/159-259 AC A0A094KEQ9.1
#=GS A0A7L1BGA2_9PASS/12-195 AC A0A7L1BGA2.1
#=GS A0A1L8GRD3_XENLA/153-336 AC A0A1L8GRD3.1
#=GS A0A3M6TIK1_POCDA/46-222 AC A0A3M6TIK1.1
#=GS A0A484GLE0_SOUCH/154-337 AC A0A484GLE0.1
#=GS A0AAE0S3Q6_9BIVA/156-332 AC A0AAE0S3Q6.1
#=GS A0A7K8MPW8_9CORV/12-195 AC A0A7K8MPW8.1
#=GS A0A6P3FQR6_OCTDE/152-335 AC A0A6P3FQR6.1
#=GS A0A2R9ALQ0_PANPA/154-337 AC A0A2R9ALQ0.1
#=GS A0A8B8WY64_BALMU/265-380 AC A0A8B8WY64.1
#=GS A0A8S3PQS6_MYTED/151-291 AC A0A8S3PQS6.1
#=GS A0AAD7YDC3_MYTSE/123-325 AC A0AAD7YDC3.1
#=GS A0A8C3FFK2_CHRPI/157-340 AC A0A8C3FFK2.1
#=GS A0A7L1VX61_9PASS/12-195 AC A0A7L1VX61.1
#=GS A0A7K7KZY7_9AVES/12-195 AC A0A7K7KZY7.1
#=GS A0A8S4SRC9_9NEOP/126-323 AC A0A8S4SRC9.1
#=GS A0A8R1WFZ1_BOMMO/125-318 AC A0A8R1WFZ1.1
#=GS A0A7K6ZBL1_ALCTO/1-85 AC A0A7K6ZBL1.1
#=GS A0A093GFZ5_DRYPU/78-239 AC A0A093GFZ5.1
#=GS A0A7L0B6M8_9AVES/12-195 AC A0A7L0B6M8.1
#=GS A0AAE0VY24_9BIVA/153-337 AC A0AAE0VY24.1
#=GS A0A093FIE0_TYTAL/78-265 AC A0A093FIE0.1
#=GS A0A7L0HCG1_AREIN/12-196 AC A0A7L0HCG1.1
#=GS A0A8C7FDD7_ONCKI/125-309 AC A0A8C7FDD7.1
#=GS A0A8C3JNJ9_9CHAR/159-341 AC A0A8C3JNJ9.1
#=GS A0A7L0KKX5_CHATO/12-195 AC A0A7L0KKX5.1
#=GS A0A9P9YGE4_9MUSC/1255-1358 AC A0A9P9YGE4.1
#=GS A0A7J7XDZ3_PIPKU/149-181 AC A0A7J7XDZ3.1
#=GS A0A836JFV3_9HYME/167-362 AC A0A836JFV3.1
#=GS F7AI13_HORSE/154-322 AC F7AI13.2
#=GS A0A7L1UHB5_PHANI/12-195 AC A0A7L1UHB5.1
#=GS A0A834KFV8_VESGE/20-215 AC A0A834KFV8.1
#=GS A0A194QAB8_PAPXU/126-320 AC A0A194QAB8.1
#=GS L5JUR0_PTEAL/135-318 AC L5JUR0.1
#=GS A0A7J8FN45_ROUAE/244-315 AC A0A7J8FN45.1
#=GS A0A8B6DMB2_MYTGA/169-350 AC A0A8B6DMB2.1
#=GS H2M1F9_ORYLA/148-333 AC H2M1F9.2
#=GS A0A7K7IDJ6_LOXCU/12-195 AC A0A7K7IDJ6.1
#=GS A0A8C6CSM6_MOSMO/154-271 AC A0A8C6CSM6.1
#=GS A0A1S3IW08_LINAN/153-339 AC A0A1S3IW08.1
#=GS A0A210R5L3_MIZYE/505-684 AC A0A210R5L3.1
#=GS A0A091SDZ9_PELCR/151-334 AC A0A091SDZ9.1
#=GS A0A091ID95_CALAN/149-331 AC A0A091ID95.1
#=GS A0A8D2PZ59_ZOSLA/173-356 AC A0A8D2PZ59.1
#=GS A0A494BB43_MOUSE/153-186 AC A0A494BB43.1
#=GS A0A3Q2EE35_CYPVA/157-340 AC A0A3Q2EE35.1
#=GS A0A195CHA8_9HYME/1-191 AC A0A195CHA8.1
#=GS A0A7L0S9E4_GLABR/12-195 AC A0A7L0S9E4.1
#=GS A0A8C4VXY5_9SAUR/17-198 AC A0A8C4VXY5.1
#=GS A0A8C2TPE9_COTJA/157-340 AC A0A8C2TPE9.1
#=GS A0A4S2L512_9HYME/167-361 AC A0A4S2L512.1
#=GS A0A8D2NBA0_ZONAL/156-339 AC A0A8D2NBA0.1
#=GS A0A067QI74_ZOONE/161-368 AC A0A067QI74.1
#=GS STING_RHIFE/154-336 AC A0A291NUI4.1
#=GS A0AAD3MXZ4_LATJO/189-374 AC A0AAD3MXZ4.1
#=GS A0A9W9Z815_9CNID/125-264 AC A0A9W9Z815.1
#=GS A0A670K211_PODMU/35-81 AC A0A670K211.1
#=GS A0A852B6J0_9CORV/12-195 AC A0A852B6J0.1
#=GS A0A6J8ER65_MYTCO/549-731 AC A0A6J8ER65.1
#=GS A0A6I9VXE6_9HYME/165-360 AC A0A6I9VXE6.1
#=GS A0A9N9TDP9_PHYSR/182-375 AC A0A9N9TDP9.1
#=GS A0A158NGD3_ATTCE/167-362 AC A0A158NGD3.1
#=GS A0A7K9EDN1_BARMA/12-195 AC A0A7K9EDN1.1
#=GS A0A8S3PVY4_MYTED/150-332 AC A0A8S3PVY4.1
#=GS A0A8S4PPU6_OWEFU/138-315 AC A0A8S4PPU6.1
#=GS A0A7K8RF74_9PASS/12-195 AC A0A7K8RF74.1
#=GS A0A2U9C7D1_SCOMX/157-342 AC A0A2U9C7D1.1
#=GS A0A7K4VWC4_9TYRA/12-195 AC A0A7K4VWC4.1
#=GS A0A7L2VEM6_9AVES/12-195 AC A0A7L2VEM6.1
#=GS I3N0T1_ICTTR/154-337 AC I3N0T1.1
#=GS A0A452C9Z6_BALAS/265-305 AC A0A452C9Z6.1
#=GS R7T8B0_CAPTE/332-531 AC R7T8B0.1
#=GS A0A8S9XZ35_APOLU/69-244 AC A0A8S9XZ35.1
#=GS A0A7L3T5J9_RISTR/12-194 AC A0A7L3T5J9.1
#=GS A0A8B8EAP1_CRAVI/155-331 AC A0A8B8EAP1.1
#=GS A0A7K9CZY8_9AVES/12-194 AC A0A7K9CZY8.1
#=GS A0A8C6K9T8_NOTFU/154-265 AC A0A8C6K9T8.1
#=GS A0A8B8X2D5_BALMU/62-245 AC A0A8B8X2D5.1
#=GS A0A091W3J6_OPIHO/159-346 AC A0A091W3J6.1
#=GS A0A8B9PPD9_APTOW/159-333 AC A0A8B9PPD9.1
#=GS A0A2U4AGG1_TURTR/100-283 AC A0A2U4AGG1.1
#=GS A0A6P7YVD2_9AMPH/163-351 AC A0A6P7YVD2.1
#=GS A0A7L1QZ42_9PASS/12-195 AC A0A7L1QZ42.1
#=GS A0A091LBI4_CATAU/159-342 AC A0A091LBI4.1
#=GS A0A6J8ERF9_MYTCO/185-383 AC A0A6J8ERF9.1
#=GS A0A7K9ZCQ5_9CORV/12-195 AC A0A7K9ZCQ5.1
#=GS A0A8C6K883_NOTFU/73-198 AC A0A8C6K883.1
#=GS A0AA89BU98_PINIB/50-219 AC A0AA89BU98.1
#=GS A0A7L4BGB1_9CHAR/12-194 AC A0A7L4BGB1.1
#=GS A0A7K5M2F0_CARCD/12-195 AC A0A7K5M2F0.1
#=GS A0A673C0P3_9TELE/157-342 AC A0A673C0P3.1
#=GS A0A851LR33_CORCR/12-194 AC A0A851LR33.1
#=GS A0A452J3B0_9SAUR/161-342 AC A0A452J3B0.1
#=GS A0A2T7NCI1_POMCA/175-336 AC A0A2T7NCI1.1
#=GS A0A671YEQ9_SPAAU/157-342 AC A0A671YEQ9.1
#=GS A0A315VL73_GAMAF/251-456 AC A0A315VL73.1
#=GS A0A7L2N7Q3_9PASS/12-195 AC A0A7L2N7Q3.1
#=GS A0A8S3UJH8_MYTED/136-258 AC A0A8S3UJH8.1
#=GS A0A8C2V0U9_CHILA/167-350 AC A0A8C2V0U9.1
#=GS A0A811YUS2_NYCPR/154-334 AC A0A811YUS2.1
#=GS A0A8B8DL69_CRAVI/398-588 AC A0A8B8DL69.1
#=GS A0A8B6CQJ8_MYTGA/527-706 AC A0A8B6CQJ8.1
#=GS A0A7K6CBR0_PTIVI/12-195 AC A0A7K6CBR0.1
#=GS A0A4W2EZ82_BOBOX/260-443 AC A0A4W2EZ82.1
#=GS A0A7L1RBV0_9PASS/12-195 AC A0A7L1RBV0.1
#=GS A0A7K5L1Q5_VIRAL/12-195 AC A0A7K5L1Q5.1
#=GS A0A8C5WHE8_9ANUR/164-347 AC A0A8C5WHE8.1
#=GS A0A6J8CZT0_MYTCO/525-699 AC A0A6J8CZT0.1
#=GS A0A7K8EQB1_LEURO/12-195 AC A0A7K8EQB1.1
#=GS A0A8C8MCG9_ONCTS/153-337 AC A0A8C8MCG9.1
#=GS A0A9J6H397_HAELO/5-175 AC A0A9J6H397.1
#=GS A0A7L1KD73_RYNNI/12-194 AC A0A7L1KD73.1
#=GS A0AAD9R2S8_ACRCE/173-353 AC A0AAD9R2S8.1
#=GS A0AA38M7V6_9CUCU/175-367 AC A0AA38M7V6.1
#=GS A0A6A4WNH7_AMPAM/3010-3182 AC A0A6A4WNH7.1
#=GS A0AAE0VNH8_9BIVA/158-334 AC A0AAE0VNH8.1
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A0A3Q2GYV6_HORSE/154-284 ..................NVAHGLA..WSYYTGYL.RLI..LPG......................LRAR....I.Q.......V.Y.N...QLHNNv...................lcGAGSHR..LH.....ILF......P....LD.C...G...VP..D...D...L......S......V......A...D.....................PN..I..C...F..L.......H.E..LP.....Q...Q........SAD..R.A.GI.KGRVY.TNSVYRL.........LE.N..G...Q.........P....N.......-.-L....QMEA..A.SPCHR-----.--..-..-..--.....................-----------------.-.----......-..-...-.-..-..-....-...-.--------.....-.-..-.-....-...-...-....-.--------------rfsstcgrrkgrllwaarr.....................
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A0A7M5UC06_9CNID/219-408 .................h-VADGLA..WSYYFGYL.KIM..LPG......................MKGM....L.A.......L.A.Q...GDEYKidge..............dirdKLSSEK..LH.....IVI......P....KN.C...Y...TY..D...S...F......K......E......V...D.....................KR..I..T...F..K.......C.S..MP.....P...I........KKT..R.G.GV.QERVY.KNTVWEV........kLE.D..D...E.........E....P.......L.YV....LMEY..A.TPVLSMYDMK.KE..E..S..AH.....................FHGQDLEDQVKEFTTKL.Q.KILD......E..D...E.E..C..K....N...K.YEIVLCGD.....V.K..S.Q....K...-...-....-.-LSEIMRRTI----qkekenk.................................
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