#=GF ID   SafA
#=GF AC   PF17073.10
#=GF DE   Two-component-system connector protein
#=GF AU   Llagostera M;0000-0001-8177-8321
#=GF SE   Manual
#=GF GA   27.00 27.00;
#=GF TC   32.20 153.20;
#=GF NC   25.60 23.70;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 90746521 --cpu 8 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   17998538
#=GF RT   B1500, a small membrane protein, connects the two-component
#=GF RT   systems EvgS/EvgA and PhoQ/PhoP in Escherichia coli.
#=GF RA   Eguchi Y, Itou J, Yamane M, Demizu R, Yamato F, Okada A, Mori H,
#=GF RA   Kato A, Utsumi R;
#=GF RL   Proc Natl Acad Sci U S A. 2007;104:18712-18717.
#=GF DR   INTERPRO; IPR031411;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   SafA is a bacterial transmembrane protein family that connects
#=GF CC   the signal transduction between the two component systems
#=GF CC   EvgS/EvgA and PhoQ/Phop. SafA interacts with PhoQ, leading to
#=GF CC   the PhoQ/PhoP system activation in response to acid stress
#=GF CC   conditions [1].
#=GF SQ   10
#=GS SAFA_ECOLI/1-65        AC P76136.1
#=GS B7L7J9_ECO55/1-65      AC B7L7J9.1
#=GS B7MMX5_ECO45/1-65      AC B7MMX5.1
#=GS B7URN3_ECO27/1-65      AC B7URN3.1
#=GS SAFA_ECO57/1-65        AC Q8XAX0.1
#=GS SAFA_SHISS/1-65        AC Q3Z1P4.1
#=GS SAFA_ECOL6/1-65        AC Q8FHF9.1
#=GS SAFA_SHIFL/1-66        AC Q7UCH6.1
#=GS SAFA_SHIDS/1-65        AC Q32FX5.1
#=GS A0A0H3EGV8_ECO8N/1-65  AC A0A0H3EGV8.1
SAFA_ECOLI/1-65                   MHATTVKNKITQRDNYKEIMSAIVVVLLLTLTLIAIFSAIDQLSISEMGRIARDLTHFIINSLQ--g
B7L7J9_ECO55/1-65                 MHATTVKNKITQRDNYKEIMSVIVVVLLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIINSLQD-.
B7MMX5_ECO45/1-65                 MHATTVKNKITQRDNYKEIMSVIVVVLLLTLTLIAIFSAIDQLGISEMGRMARDLTHFIINSLLD-.
B7URN3_ECO27/1-65                 MHATIVKNKITQRDNYKGIMSVIVVVLLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIINSLQD-.
SAFA_ECO57/1-65                   MHATTVKNKITQRDNYKEIMSVIVVILLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIVNSLQD-.
SAFA_SHISS/1-65                   MYATTVKNKITQRDNYKEIMSVIVVVLLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIINSLQD-.
SAFA_ECOL6/1-65                   MHATTVKNKITQRDNYKEIMSVIVVVLLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIINSLQD-.
SAFA_SHIFL/1-66                   MHATTVKNKITQRDNYKEIMSVIVVVLLLTLTLIAIFSAIDQLSISEMGRIARDLTHFIINSLQD-w
SAFA_SHIDS/1-65                   MHATTVKNKITQRDNYKGIMSVIVVVLLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIINSLQD-.
A0A0H3EGV8_ECO8N/1-65             MHATIVKNKITQRDNYKGIMSVIVVVLLLTLTLIAIFSAINQLGISEMGRIARDLTHFIINSLQD-.
#=GC seq_cons                     MHATTVKNKITQRDNYKEIMSVIVVVLLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIINSLQD..
//