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Database: Pfam
Entry: Spc29
LinkDB: Spc29
Original site: Spc29 
#=GF ID   Spc29
#=GF AC   PF17082.7
#=GF DE   Spindle Pole Component 29
#=GF AU   Llagostera M;0000-0001-8177-8321
#=GF SE   Manual
#=GF GA   31.00 31.00;
#=GF TC   31.00 33.00;
#=GF NC   30.90 30.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   10339566
#=GF RT   Spc29p is a component of the Spc110p subcomplex and is essential
#=GF RT   for spindle pole body duplication.
#=GF RA   Elliott S, Knop M, Schlenstedt G, Schiebel E;
#=GF RL   Proc Natl Acad Sci U S A. 1999;96:6205-6210.
#=GF DR   INTERPRO; IPR031392;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Spc29 is a component of the Spc-110 subcomplex and is required
#=GF CC   for the SPB (Spindle pole body) duplication. Spc29 acts as a
#=GF CC   linker between the central plaque component Spc42 to the inner
#=GF CC   plaque component Spc110 [1].
#=GF SQ   18
#=GS SPC29_CANGA/1-230       AC Q6FP43.1
#=GS A0A1S7HCC9_9SACH/5-63   AC A0A1S7HCC9.1
#=GS A0A1G4MHM1_LACFM/1-226  AC A0A1G4MHM1.1
#=GS H2AZC5_KAZAF/8-226      AC H2AZC5.1
#=GS A0A1S7HPW5_9SACH/5-62   AC A0A1S7HPW5.1
#=GS A0A1G4J6E8_9SACH/4-208  AC A0A1G4J6E8.1
#=GS SPC29_ASHGO/55-290      AC Q75BW4.1
#=GS J7SAJ3_KAZNA/11-172     AC J7SAJ3.1
#=GS J8Q1A3_SACAR/1-251      AC J8Q1A3.1
#=GS SPC29_KLULA/1-272       AC Q6CRT5.1
#=GS J6EDL3_SACK1/1-251      AC J6EDL3.1
#=GS SPC29_YEAST/1-251       AC P33419.1
#=GS G8JXL1_ERECY/1-257      AC G8JXL1.1
#=GS A7TKY7_VANPO/6-246      AC A7TKY7.1
#=GS A0A1G4IZT6_9SACH/5-213  AC A0A1G4IZT6.1
#=GS A0A0C7N8A2_9SACH/8-227  AC A0A0C7N8A2.1
#=GS C5DXL9_ZYGRC/5-46       AC C5DXL9.1
#=GS C5DEV0_LACTC/5-214      AC C5DEV0.1
SPC29_CANGA/1-230                  .........MVVGPISNLRDDALKDDTLNHIRKEYLESKKQISNL.LSQETN..TN...EFSRKPypnsSPI..RKFDHFANE.........---------RPTTIDAKLREQLRTGASDV.....---AIEQ.SL......RT.NSDESR.....NQMI.....Y..DD..MKV---MKR.....IIDGQQESIRELRRALEQERYMNSELQRKYNEMERRF.........DRLEW.FINSHDK..............FQ.AYQ...............DIRSNTTKKDFSDPIFNNGLKRR....WDEYPIRSFEPDT...NI---NRNN..RIFSNYDDSTTRLMQITDPHY..........
A0A1S7HCC9_9SACH/5-63              ......tre-----FFERPEN---DDTLQNIRRQYLESKRNLQDL.MMKQGDeeTKirtEFVSS-....---..---------.........-----------------------------.....-------.--......--.------.....----.....-..--..---------.....-------------------------------------.........-----.-------..............--.---...............-----------------------....-------------...---------..---------------------skpprepekk
A0A1G4MHM1_LACFM/1-226             mnhssargl------RNMPEA---DDTLHKIRRDYLMSKKNLQEL.LTASST..--...RLSGNS....ARI..GP-------.........-LPTPPLQSSEALSDEKLRQQIRQGLQKD.....-EPPLRS.PQ......AS.------.....LQHM.....T..SS..ADL-AYLRQ.....LMRDQQRQIDDLTRRLHSQSVSNKALQDRVTMLEDYV.........---SQ.MEASNRQ..............TR.KYNyn..........ytkS-----ALSSSSSLGRSTAPSES....YDAYTGPELDNTNyllDLTPGKIQH..RDFSNLDDSTTRLLQLAQ---nah.......
H2AZC5_KAZAF/8-226                 .......tk----DFFNRAST---QDSLRDIMKESEEIMKRNGSL.----QD..TT...VFNRSK....DKL..LY---GKND.........--GYNDRLQTDSLLDDKLRQQLR-GNAPL.....PSSRIPS.AStllennRS.NSQRSNdmekiIDFM.....Y..KS..SNEIKLLKQ.....TVHDQSLELKNLKNELGLQRQENLNLNFKIKDLDRTIrv.....ndRDLPY.LENNQRSssanlnyepnrslsFR.NYS...............DRFNDTRFQEYPRN-YEEEDT--....-------------...---------..---------------------kkllntr...
A0A1S7HPW5_9SACH/5-62              ......tre-----FFERPEN---DDTLQNIRRQYLESKRNLQDL.MMKQGDeeTKirtEFVS--....---..---------.........-----------------------------.....-------.--......--.------.....----.....-..--..---------.....-------------------------------------.........-----.-------..............--.---...............-----------------------....-------------...---------..---------------------sskpprepen
A0A1G4J6E8_9SACH/4-208             ......qsf---NDFFNKVDT---DDTLQNIRKEYLASKKNLHEL.------..--...-ISASP....TRItaKPVVRSTQL.........PT--PPGNINDLERDERLRRQLHDTNQPR.....-------.--......QP.DTGHS-.....----.....-..--..-EQFSRLES.....LIVEQQRQLDRLRYQLDQYEITNRALRERTYAVEHEL.........RQLRY.TGSL--S..............ID.SYP...............RRETRTAESRVRDNEIGD---LD....FDNTKA--LLSSS...RI--EKSQR..RQFSNLDDSTTRILQMTK---npq.......
SPC29_ASHGO/55-290                 .........MNVSSFLNRPDT---DDTLQNIRKEYLNTKRNLHDL.------..--...-LSSSP....TRL..QQGARGAGEmsgnapplhYVGGQAEPPQQGEQDDRLRQQLRDYMSNKsrsmpPPAKYPA.PG......PG.PADGG-.....----.....-..--..------VQR.....QLDSQKMMIESLKRELDTQRTINSMLFERLDRLEEEV.........---RY.VRHSNRApan........gapFR.SVS...............SAPSSSHTNGHVGS-YASADDTKvllgWDQPTL--AHGGK...HAQPPQQHT..RTFSNLDDSTARLIQMSAGG-k.........
J7SAJ3_KAZNA/11-172                ......fvr----TFFSRPET---DDTINNFKRDYMESMKKLNMV.LNTSRN..GSp.mRGTTGP....KKV..KEVD----Elnir.spprIPNERVQSNRKLDDNDNVRLQFK---TRE.....PNSRISStST......LG.PSDEQ-.....---I.....H..VL..IDEMKELRE.....TLYRQQTQLQALKVDLKQERQKTSFLQYKVDRLES--.........-----.-------..............--.---...............-----------------------....-------------...---------..---------------------gsrtvpq...
J8Q1A3_SACAR/1-251                 .........MDYNNFGGSASKKYQDDTLNRVRKEHQEALKKLRNE.------..--...NFNSNS....PDLgnKKSYKTQERmspplhrlsPVNRPEDKKMRSPLDDKLRRQLREGNTRL.....PPPPFSS.YG......VP.SNNRSN.....LDRI.....R..RR..TSSPVRTERfasqdVIDDQRLEIKYLERIVHDQGSIIDNLTSRITRLESIIlntfpdrgeNNSAS.LEHS---..............-N.SFS...............GFPTNKAYGLQMGGLHEN-----....-GAPYRRSSDNIK...KEKPRLDRP..SSIHLENESTEDILKILSSS-f.........
SPC29_KLULA/1-272                  .........MDVSQFLNNVEN---DDTLQNIRKEYLNSKRTLQEL.MTNQSP..TKk.mEFSKKP....TLL..QE--RNSND.........YINRNVNSSKPTD-DEFLRRQLREGLSRK.....PEPKISL.PS......LA.-SDTNR.....LDSI.....Y..SS..VNKIDELEK.....KLYHHELQIQALKNELYQSNASNRALQNKVAELQDSV.........RMLAA.LSHSNVKadtdnsqlsangkwTR.HYAgpnsngngvyldrpqSAPSTSSTSEWVANALHDSDDTRvllgWKQPSSTRVDNSS...NFHFPHNQP..RNLSNFDDNTSRLIGVTGKTR..........
J6EDL3_SACK1/1-251                 .........MDYKNFGSNAGKKFQDDTLNRVRKEHQEALKKLREE.------..--...NFSSNT....SELgkNKQYKAQERmspplhrlsPVNKLEDRKLRSPLDEKLRRQLRESNTRL.....PPPSFSS.YG......IP.SNNRSN.....LERI.....R..RR..TSSPVRTERfasqdVIDDQRLEIKYLERIVHDQGSIIDNLTSRITRLESFIlnpvsdreeKNFGS.LEHS---..............-N.SFA...............GFPTNKMYGLQMGGLYEK-----....-DMPYGRSSDNIK...KERPRVGRS..SQIHIENESTEDILKILSSS-f.........
SPC29_YEAST/1-251                  .........MDYSNFGNSASKKFQDDTLNRVRKEHEEALKKLREE.------..--...NFSSNT....SELgnKKHYRAQERmssplhrlsPTGKSDDRKVKSPLDDKLRRQLREGNTRL.....PPPPFSS.YG......MP.PTNRSN.....LDRI.....R..RR..TSSPVRTDKfasqnVIDDQRLEIKYLERIVYDQGTVIDNLTSRITRLESFIlnsisdrgdKNFAS.LEHS---..............-R.SFS...............GFPTNKTYGLQMGGLYEN-----....-DMPYRRSSDNIN...KEGAREDRS..SQIHIENESTEDILKILSSS-f.........
G8JXL1_ERECY/1-257                 .........MDRSSYLNRPET---DDTLQNIRKEYLNTKRNLHDL.LT-SSP..TR...IPQSTR....GEL..--------Ggkaa.aglqQQQGAQLAAQDAEQDDRLRQQLRDYMNNRgrhmgAPARYPS.VG......AAaPPAPPL.....LQAAgggsaA..AV..APVEGSLQR.....QLDNQKLMFDSLKRELDTQRTINNMLFQRLDQLEEDV.........RYLRH.ATNN--Kaqqqqn..nnvggnFR.SVS...............SAPSSSHTTGFGGS-SVSGDDTKvllgWDQPSN-----AV...KQ--HHPHQ..RSLSNFDDNTAKLIQMSSGA-k.........
A7TKY7_VANPO/6-246                 ...ltkeff-------DRQEV---DDTLQNIRKQYLESKKNLQKLvMMKQSP..ANt.eEF-KVP....SIP..KQ-------.........---KPPKPTRPSDIDEKLRRELRS--SRV.....TTNTVEN.T-......PA.PLGKET.....ITDT.....L..IL..VNEVRSMKN.....IIQEQRAMIRDLSQDLQVQRSMSYELQSKIHRLEAHI.........RQVELnMRGSKQPyge........ypgND.IFD...............TNRSNYSTTEIENIPKRSAWRTHsltaPSSSSHSSYSNSS...NMNNINNSYsyQSYSTMEDSTTRLIQLSNP--k.........
A0A1G4IZT6_9SACH/5-213             .....gttg-----FFNDPET---DDTLQNIRRDYLASKKNLQEL.------..--...-LVTSP....TTT..RT--RPLQV.........PT-PPMERKTRGN-DELLRQQLREGLRID.....--SRHPS.GS......LP.PAARRD.....LPRK.....VepEH..YTEVDGLRM.....MVHDQQQSIGRLQRALEAQEARNANLEMRMRTLEHCV.........---AI.LEKS---..............PR.SPY...............E-PRNTEPPGAYESVDHD-----....-NTKVLLNLDGGQ...PV------Q..RLHSNYDDSTTNLIKLSQ---issq......
A0A0C7N8A2_9SACH/8-227             ....gffsd---------PET---DDTLRNIRREYLASKKNLQEL.------..--...-LITSP....TSM..RTRQLQNPT.........PVTDFSRKDGRLNNDDHLRLQLREGLKSD.....--PEIMP.AG......AT.PSSYKT.....FQKI.....G..QSkaYNEIDTMRS.....MLYDQQRQINQMQRDFESQGQRNAALHDRVYYLERTV.........AKLEA.ELETQST..............VRdSYE...............PVVRPLRTKIPAPVEFQDHDNTR...aLLNPQS--MD---...-----MAAK..RQISNYEDSTTRLIQMAQD--sn........
C5DXL9_ZYGRC/5-46                  ......tre-----FFDRPEN---DDTLQNIRRQYLESKRNLQDL.MMKQNQ..--...------....---..---------.........-----------------------------.....-------.--......--.------.....----.....-..--..---------.....-------------------------------------.........-----.-------..............--.---...............-----------------------....-------------...---------..---------------------ngdad.....
C5DEV0_LACTC/5-214                 .......gl---SAFLSNPET---DDTLQNIRREYLASKKNLQNL.------..--...-LVTSP....TRA..RT--RPLQQip.....tpPINGS---KERAD-DDKLRQQLREGLQPDrf.mnRPPQVPI.PT......AA.RSD---.....----.....-..--..IE---NLRS.....MLYSQQRVIDELTRGLDAQVIRNSALENRVSMLERYI.........TRLES.QGNSRSP..............EP.QLV...............DEGISRRLRQQYTPLYTD-----....-DENTR-VL---L...NSGAVDRPD..RQISNFDDSTTKLLQIARD--ts........
#=GC seq_cons                      ..............FhspsEs...DDTLpNIR+EYLpSKKNLp-L...............hsoss....spl..pp......t............t..t.ppcs..D-+LRpQLRps.pp........sth.s.ss......hs.ssstp.........h.....h......hs...thcp.....hl.cQphpIctLpptLcpQtthsptLpp+lppLEp.l.........t..t..htpo..................p.phs...............s..psptht...ss.hps..........st.............p......t...pphp..s-STpcllph.p...p.........
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