GenomeNet

Database: Pfam
Entry: SpoIISA_toxin
LinkDB: SpoIISA_toxin
Original site: SpoIISA_toxin 
#=GF ID   SpoIISA_toxin
#=GF AC   PF14171.8
#=GF DE   Toxin SpoIISA, type II toxin-antitoxin system
#=GF AU   Eberhardt R;0000-0001-6152-1369
#=GF SE   Jackhmmer:O34853
#=GF GA   27.00 27.00;
#=GF TC   33.80 33.60;
#=GF NC   22.60 21.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Toxin-antitoxin_system
#=GF RN   [1]
#=GF RM   21147767
#=GF RT   The structure and interactions of SpoIISA and SpoIISB, a
#=GF RT   toxin-antitoxin system in Bacillus subtilis.
#=GF RA   Florek P, Levdikov VM, Blagova E, Lebedev AA, Skrabana R,
#=GF RA   Resetarova S, Pavelcikova P, Barak I, Wilkinson AJ;
#=GF RL   J Biol Chem. 2011;286:6808-6819.
#=GF DR   INTERPRO; IPR025940;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   SpoIISA is a toxin which causes lysis of vegetatively growing
#=GF CC   cells.  It forms part of a type II toxin-antitoxin system, where
#=GF CC   the SpoIISB protein, Pfam:PF14185, acts as an antitoxin. It is a
#=GF CC   transmembrane protein, with a cytoplasmic domain accounting for
#=GF CC   approximately two-thirds of the protein. The structure of the
#=GF CC   cytoplasmic domain resembles that of the GAF domains, Pfam:
#=GF CC   PF01590. SpoIISB binds to the cytoplasmic domain of SpoIISA with
#=GF CC   high affinity [1].
#=GF SQ   59
#=GS W9AM12_9BACI/3-241       AC W9AM12.1
#=GS N4WN46_9BACI/9-289       AC N4WN46.1
#=GS A0A368W9T4_9BACL/11-278  AC A0A368W9T4.1
#=GS A0A0K9GDU3_9BACI/3-264   AC A0A0K9GDU3.1
#=GS A0A0C2RUD9_9BACL/2-239   AC A0A0C2RUD9.1
#=GS A0A431W0Z4_9BACI/7-272   AC A0A431W0Z4.1
#=GS A0A3L7JTT6_9BACI/1-250   AC A0A3L7JTT6.1
#=GS I0JTA5_HALH3/2-276       AC I0JTA5.1
#=GS E3EKM2_PAEPS/2-264       AC E3EKM2.1
#=GS A0A176J2G6_9BACI/1-256   AC A0A176J2G6.1
#=GS A0A0A3IXP0_9BACI/46-306  AC A0A0A3IXP0.1
#=GS A0A401HVE9_9BACL/14-224  AC A0A401HVE9.1
#=GS A0A0M5JFQ7_9BACI/11-290  AC A0A0M5JFQ7.1
#=GS A0A1H9RBX5_9BACI/2-260   AC A0A1H9RBX5.1
#=GS A0A094WP87_ALKAL/50-309  AC A0A094WP87.1
#=GS A0A0J1IPS7_BACCI/5-274   AC A0A0J1IPS7.1
#=GS SP2SA_BACCR/5-243        AC Q81DD1.1
#=GS Q65KZ9_BACLD/3-239       AC Q65KZ9.1
#=GS A0A556PL46_9BACI/5-156   AC A0A556PL46.1
#=GS A0A176J295_9BACI/3-239   AC A0A176J295.1
#=GS SP2SA_BACAN/12-246       AC Q81QD6.1
#=GS A0A1G6J4W6_9BACI/3-239   AC A0A1G6J4W6.1
#=GS A0A2M8TGH7_9CLOT/3-260   AC A0A2M8TGH7.1
#=GS A0A4Y9ABC4_9BACI/22-260  AC A0A4Y9ABC4.1
#=GS A0A1Q2L2F5_9BACL/3-236   AC A0A1Q2L2F5.1
#=GS A0A327RPB6_9BACI/38-298  AC A0A327RPB6.1
#=GS A0A0M0GFV8_SPOGL/3-239   AC A0A0M0GFV8.1
#=GS A0A4V3B125_9BACL/8-285   AC A0A4V3B125.1
#=GS A0A4Q0VMM2_9BACI/1-217   AC A0A4Q0VMM2.1
#=GS A0A0M2EE55_BACIA/3-239   AC A0A0M2EE55.1
#=GS A0A419V0D0_9BACL/62-314  AC A0A419V0D0.1
#=GS A8FC77_BACP2/3-239       AC A8FC77.1
#=GS A0A498DFG2_9BACI/3-239   AC A0A498DFG2.1
#=GS A0A098EZE6_9BACI/4-270   AC A0A098EZE6.1
#=GS Q5WGM8_BACSK/3-239       AC Q5WGM8.1
#=GS A0A060M2F0_9BACI/2-216   AC A0A060M2F0.1
#=GS A0A285D6U4_9BACI/35-280  AC A0A285D6U4.1
#=GS G2TPX2_BACCO/4-240       AC G2TPX2.1
#=GS A0A3N5ZUI9_9BACL/3-280   AC A0A3N5ZUI9.1
#=GS SP2SA_BACSU/3-239        AC O34853.1
#=GS SP2SA_BACSU/3-239        DR PDB; 3O6Q A; 97-239;
#=GS SP2SA_BACSU/3-239        DR PDB; 3O6Q C; 98-239;
#=GS A0A1J6W3H6_9BACI/3-275   AC A0A1J6W3H6.1
#=GS A0A0U1NYW0_9BACI/40-286  AC A0A0U1NYW0.1
#=GS A0A3E2JE45_9BACI/3-265   AC A0A3E2JE45.1
#=GS A0A1H3V1Y1_9BACI/3-64    AC A0A1H3V1Y1.1
#=GS A0A0A3HM51_9BACI/2-280   AC A0A0A3HM51.1
#=GS W7YZW3_9BACI/3-238       AC W7YZW3.1
#=GS A0A2C1ZFB9_9BACI/51-291  AC A0A2C1ZFB9.1
#=GS A0A6I1FJJ4_9BACI/4-274   AC A0A6I1FJJ4.1
#=GS A0A0V8JCE8_9BACI/2-238   AC A0A0V8JCE8.1
#=GS A0A3S2UZB7_9BACI/38-282  AC A0A3S2UZB7.1
#=GS A0A317L5K3_9BACI/6-291   AC A0A317L5K3.1
#=GS E6TS07_BACCJ/5-263       AC E6TS07.1
#=GS A0A0M1NLQ7_9BACI/2-240   AC A0A0M1NLQ7.1
#=GS A0A366E413_9BACI/1-208   AC A0A366E413.1
#=GS I8UEB9_9BACI/6-268       AC I8UEB9.1
#=GS A0A1B9B080_9BACI/1-264   AC A0A1B9B080.1
#=GS A0A1I4KPU8_9BACI/7-288   AC A0A1I4KPU8.1
#=GS S2XV84_9BACL/43-288      AC S2XV84.1
#=GS A0A1H3V2F0_9BACI/1-176   AC A0A1H3V2F0.1
W9AM12_9BACI/3-241                  ...........................tfa---LIGMW.LV.FAL.L.L.IYT.VI....A...WL-....NR....GLENYTSAIRKTWYVIFIFGSLVFISDNPSL.lFTNWNNYLIVLFIFVIVDSLVFLNLYVSTLGGHQLES-...VKVQVGVTQEELEENNRKTGHIPDIL.T--SFDFP....IN..T.LDK...D..EYIFQLGEILNKYAQRENLVIDLLPYET..E..............................EE..K..E...S.I..FEGLG.RNKK--...........................--RAERFLSQQHSI..LL.E...K...........D.H......L..GLYPYHI.LKRFYVVQVqtvNEG..N..KI.SKIDGLVINTLIITFSL-a..
N4WN46_9BACI/9-289                  ...........................svs-----VVV.LL.VFI.L.Y.VYI.QS....W...MSF....REkgnnQFNENLYQYRKTLYVLFVLVIGMLLLMQTIS.iEDNWKLLMMLAGMIVFIDIFVFSTPTIKKIWKTEFQAYd.pLKQYIQENSLIEEKQKDKLNYFSQLV.QIAPFLKN....DI..A.KKR...L..DIADSLALFLSYYADHFGLRVHLYNVGE..Khk..........................itSD..V..D...H.L..FSEFG.ETLQAIkhthtldwctm.....psnitkededaERTVVETLWNGDII..AL.D...R...........E.DkhgkgiA..HLCPIFV.GEDIFVLFI..eEIH..Q..QV.YEMDALFLTNLACLYCF-l..
A0A368W9T4_9BACL/11-278             ..........................yfgf-FFTSIIV.YL.FYS.I.-.---.-Y....Q...FRK...dAE....KFSDDIWRIRKVFYVLFLTLTGIGVVAGYVD..FRDWKILLQLTAFVVFIDLAVFQTPSITKIWSAEFQHRa.kIEKTIEVNVDFINSTAIKLQAFSDVI.KQTADYFEp.ktDI..P.QNW...N..AYQRELKQFLSLYTSQFRFRLEMFHFRI..G..............................SD..E..T...E.T..KQHIG.RALSQLetlflyeldd.......apdkdnqpgfRTQVVDKLTSGIGT..SL.E...T...........D.K......L..IVIPIFQ.NR-SLLIGIr.tSEG..S..RV.DEVDITNIVNLSRIFHW-y..
A0A0K9GDU3_9BACI/3-264              ...........................gki-----CVA.LIvLFA.I.Y.SCV.MA....I...VR-....PS....QFDLNLKKKRRVLYTIFIATTGSGVVLGGLE..LDDWPYVVSLASIVVFTDLAVLLTPSILRIWQAEFLHGselLEETLKENERLIRDMMAKVSFMSFLI.QDAIYYFE....KKpiP.ETD...E..DYLAELEQYLQQYGDRFGLNIDVRQYEI..D..............................PN..T..DlevS.V..QAKIR.QELL-Imkdmhn..............igmelsrLEEYIVSIYNGEII..TL.E...E...........D.E......T..FIVPVQL.PKYHFIVVI..kKGK..G..TP.IEIDGIHTANLVHIYD--sf.
A0A0C2RUD9_9BACL/2-239              ............................lw-FFRIFVW.AI.FIG.L.V.SYV.FV....F...WKY....EE....KVNDKLPAIRKIWYLLFILGSLVFWSFEPAS.iFTHWVHYFIVAVFFTMVDGFVFLSLYLRKFGGGELEAA...TQKTVERSHELIKDHIDKIKNVLFVL.NRSDQ--F....EK..S.STH...S..QYLSGLQSVLQAYAEQEKLTIELFPFSS..R..............................ED..R..K...Q.L..LAGVK.NHQL--...........................---LRSKLHRAEIY..YH.E...E...........D.H......A..AYYPIGI.LTGKYVVKI...TSS..S..YV.SEVDCALIGILLASYDW-a..
A0A431W0Z4_9BACI/7-272              .......................wymitif-------S.VL.MIG.I.A.FSIgLY....I...WS-....RE....FYLKHRVAIRKIYYGVVVATSFFLWAFNVFPdvGAKLEYLIALVISVVIIDLFVFQTPDITKFFTNELKQE..sLVESINKNRGTFIELSEKLIKVNELM.PKSDQKWH...lDE..FeFTP...E..KYEEFVLSYLRNFTSS--FQLDVYSYLV..E..............................SS..A..D...E.IifHNNIV.SAYEEIlkdhnfg.............lrevgmrKNQVIKTLLEGENIeiLE.K...D...........S.S......S..VLFPYFG.EYYNLLFVV...SSRkgS..EV.TGADASLMLNMLYTFDMW...
A0A3L7JTT6_9BACI/1-250              ........................myvqml-----LAV.LL.IYI.V.G.IWL.FS....V...FR-....QM....EYYLVLRMLRKTFYVIFVVGLGIGVIVGDLE..PADWKLILQLAAVIVFIDISVLLTPSIMKIWNTEFQYGd.fFKDTIQKNDAIQRNMVKKTNYMSYML.QQTTLPFE....--..-.---...-..GEPVTLHQYLNIYAEQFGLSVFVYELGN..S..............................IE..E..G...E.L..RASIR.STLSTItntyn.................ieeldTDDIAVMLFESEIV..SL.D...G...........E.D......L..MIIPAYP.SSANMVLAVl.hNQN..G..IL.LEVDAIHIANLVYLYD--sf.
I0JTA5_HALH3/2-276                  ........................afnffv------GA.LL.VFT.I.G.NYL.FF....L...WD-....QQ....KYWLSLTKIRKTLYTLFVSALAVGLLVRETH..LSNWPFILTLTTIIIFMDLALLLTPSIMKLWKAEFEHNn.dLQNIILTYEKVRKANYRRVETMSAMI.QNAHNYFP....ED..Y.FPM...L..SRARDIERYLKEYTDLYGISVQVSPLEV..Sppeynpgwe...........tmseeekyeyEE..V..Q...P.V..YEAIL.RQLDTIeathn................femgnhKEEYADYLLQYEVV..SL.I...E...........E.E......S..MIVPVIN.QKEHYLIVL..kSER..G..EV.LEIDALHIVNLTNLYHL-y..
E3EKM2_PAEPS/2-264                  .............................y-YFGWLVI.GF.FAI.V.G.LAS.IS....H...WAN....PV....WYANNLINIRKTSYSLFILMYGGMILAGHIH..LKDWGMAVQFASIAIFIDLAVLETPSILKIGNAEFKKNdmeIEKTIKDNQKTILQSFQKSEQFTDVV.QYTSNHFYpldsDN..F.IEW...D..LYMEQLKKYLRLYTDTFHFKLSITQFTY..K..............................ED..I..E...Q.R..EQNIE.GSLVQIerfhs.................inikdKAELAGTLAKANVS..VI.K...E...........Q.E......I..IGVPFFG.NRFSYIVTLeanAQE..S..VI.NAIDAYHIVNLLTVFEWF...
A0A176J2G6_9BACI/1-256              ........................myvqwl--FLIMVL.YS.A--.-.-.AAI.VL....Y...MIN....RS....VYSSLLQALRKWLYALFLLFLSVCFFFQILS..MKDWPLILQLAAAAVFIDLSIFQTPNIQKIGSAEFKHSe.wIEQTIQHNERTLEYMRKKSTAFSLII.QEEEDLMPk..eSS..L.QSF...E..DYERSITAYVEIYTDQFDFHVKLYHLVG..D..............................DD..YhfT...Q.S..IHQVL.GRLETIfni....................sindKQHVTDQLKQARVH..SF.N...E...........E.T......V..AVIPIYG.HY-SYLLIL..sARE..N..SV.MEIDTLHVINLVKILEW-r..
A0A0A3IXP0_9BACI/46-306             ..................fmnilfggfall--------.--.---.L.L.VVL.AY....Y...WMN....SR....GYYNNLGRIRRTFYTLYFIFMIVGFISENID..YNNWEILLQLSALVVFVDLAVFQNPNILKIWNTELKQDd.eVREALNESKEVIKKNSKKVEKFTQIV.QQTDTYFDn..kPI..P.TNM...N..EYRQQVTAYLEQYSNVMDFTTSFFMFES..P..............................QT..E..E...D.K..KQSIQ.QQIRDIgirhaid.............fskkqedKDAMLKSFSEGETL..IL.K...E...........G.K......L..IAIPYFG.DLYCMIVTI..eSKT..E..LV.DGIDASHILSMLIIFDW-y..
A0A401HVE9_9BACL/14-224             ........................fpdvge--------.--.---.-.-.---.--....-...---....--....-------------------------------..--NLQHLIALVISVVIIDLFVFQTPDITKFMSNELKQE..gLVESINKNRGTFIELSEKLIKVNEMMpKNLSDWHM....DN..FqFTP...E..KYEETVSSYLRTFALN--FHLDIFSYRV..Ea............................sAV..E..E...K.F..RENVS.LAYNSIikehglt.............trgvgmrQNQAISTILAGENI..EI.I...E...........G.N......StcVLFPYFG.EFYNLLFLVr.sKKD..S..EA.TGADASLMLNLLYTFDLW...
A0A0M5JFQ7_9BACI/11-290             lafsvimivlasgtailfsvsfmklffgss--------.--.ILY.L.F.LAV.VY....Y...WVD....SR....GYWNNLGRIRRTFYLLFLILISVGFMTESIS..YLNWQQVITFVAMAVFADLAIFQTPHILSIWNTVFVQEn.eVRDALKESRQTILMNAKKAEKFSEVI.QNTDIHFD....EMpfP.VSG...K..EYEQQMEEYICLYSGVFGFAITIFLFPV..L..............................ES..K..K...E.K..ELHID.KTLKNIsirhah...............qmteddREQLAVELSEGQIQ..VL.Q...E...........D.R......L..IAIPYFG.NYYSIIVTV..eAKD..V..AV.DPIDASHVSSLLYIFDW-y..
A0A1H9RBX5_9BACI/2-260              ...........................efn---IFIVV.LI.LFV.I.G.NFL.FF....M...KA-....PD....KYLISIYGLRKLLYTLFVGAILIGLLWDEIS..LSNWKFLLTLSSLVLFIDISILLTPSIMKFWHAEFNYPe.nVQKSIKESKRLRDRILYRVGTMSEMI.QNVGSYIQ....VV..S.TDE...D..ERIEDTETFINEYCDKYGLNTKLFRLTI..Qn............................vES..E..Q...A.L..FRTLLgETLEQIdrdyg................lslslnREENIDVLFDSSVL..SV.L...D...........E.G......F..MILPVYM.DGNNLLAVI..eSKK..G..EI.LEVDAVHITNLIFLYH--sf.
A0A094WP87_ALKAL/50-309             .................sflflllgttsim--------.--.---.L.I.FIL.AY....Y...WIN....SR....GFYNNLGRIRRTYYTMFIVLIVVGFIFKEIE..FSNWIMLIQLTFFAIFIDLAVFQNPNILKIWNAELKHEd.eIREALLESKEIIVKNSKKVEKFSDVI.QKTDSYLL....ER..P.IPK...DsrEYEEQLKEYTLQYSSSLGFKTGLFLFES..T..............................EN..Q..E...T.N..KENID.KKFQDIcvrhgn...............dvsqknKNDMVETLLSGQTI..IL.K...E...........N.K......L..IAIPYYG.DIYSMLITI..eGVD..V..VV.DGVDASHILNMIVIFDW-y..
A0A0J1IPS7_BACCI/5-274              ...........................yfv-FITAMIL.LI.VLS.L.-.--I.YF....W...WR-....TD....KYVENLQAIRKSYYVLFFLLVCLGILTKQLQ..MADWTMILSLACAAVFIDIAVFQTPDILKIWNTEFQHSn.yIRKTIRKNEEVLGYNAKKVQNFTEVI.SKTADHFMe..rNL..P.QHW...R..QYKDELRTYLNLYADTFQFHIAIFPFAI..S..............................AS..A..E...D.L..KQNLE.SAFNSVeicyni..............sfldrevKENVIQDLLAGKSI..PL.K...DpesninnedlvK.N......V..FIVAYYG.ESYNMLIGI..sSQF..V..EV.DGIDASHILNLAQIFDW-y..
SP2SA_BACCR/5-243                   .........................irigl-FVLAIVF.--.---.-.V.VLV.FF....Y...WKN....EE....LYEEKKQRIRKTWYGLFIISVTVYFMIKGID..LTLWKNLLMFTAMVIFVDIAFILTPNISEIWGAKFSD-...IGKTVQSIKRSLIASKARGEIYTTII.QNVNPAVFg..tME..W.HTE...E..EYTKSLNAFLDSYGEK--IGAKIVVFEA..A..............................KE..L..N...T.N..FRGIR.SQFSII..........................vPLEHIEQLNEQKAV..--.Q...V...........E.N......V..GIIPAKIvSDVFIVID-...GKK..N..NL.QDRDFENVYNLTIHHSYF...
Q65KZ9_BACLD/3-239                  ..............................LFYQFLVW.LI.VLA.L.A.LYV.AA....V...WRF....EK....QLAEKTVAIRKTWYLLYVIGAVIYWTHDPQS.iFTNPLHYLIVAVFFTLTDAFIFLNAYFKKLGSSELATD...TRMLLEENNDLLHTYQNRLKTFQYLL.KNEPIHIY....--..Y.GNI...E..AYAEGIEKLIKRFAEKMNISAALCEYNS..E..............................ES..K..D...H.L..LEHME.NRFD--...........................---VQEKLDRKDVY..YE.E...N...........G.K......M..VLIPFSI.HDFDYVMKL...TSE..D..LV.TEFDYLLFTSLTSIYDL-l..
A0A556PL46_9BACI/5-156              ....................slvnelrsfe--------.--.---.-.-.---.--....-...---....--....-------------------------------..--------------------------------------...---QIEQAEKYLDSTSRKIESMKNLL.NTFEFTRY....--..T.ISR...E..QYFSELERFLDEYGNEEGLNVQIFSYEA..E..............................KD..Q..E...N.Y..LKRIN.QSKA--...........................--RVKRSLRNYETY..FS.V...N...........D.T......K..MCIPITV.LNEKYVAEVksiISN..S..EV.ERIDGNIINILLVAYV--lv.
A0A176J295_9BACI/3-239              ..............................LFYQGLVW.FV.LCL.L.A.FYG.IS....H...WIW....ED....RVKKASESIRKTWYVLFLLGAAVFWTAHPAS.lFSDWKNYLIVFGVFVLIDAFLFLGMYIKKLGVNELER-...HTEVLEENVRLVQENNHRLKTFANLL.QHVSINLY....--..Q.GGI...A..EYMQGLDELIQLFAEKNDLTASFHSFDT..D..............................QE..K..E...Q.L..LGVIE.RKGS--...........................---IRSALERNEIV..YR.P...E...........E.K......T..ALIPIEI.QGVTFVLKI..kAAA..D..EV.NESDCLLFLSLIHMYDI-i..
SP2SA_BACAN/12-246                  ..............................LFILAIVF.LV.L--.-.-.--V.FF....Y...WRN....EE....LYEEKKQRIRKTWYGLFIVSVTVYFMIKGID..LTLWKNLLMFTAMVIFVDIAFILTPNISEIWGAKFSD-...IGKTVQSIKRSLIASKARGEIYTTII.QNVNPAVFg..tME..W.HTE...E..EYTKSLNAFLDSYGEK--IGAKIVVFEA..A..............................KE..L..N...T.N..FRGIR.SQFSTI..........................iPLEYIEQLNEQRAV..--.Q...V...........E.N......V..GIIPAKIvSDVFIVID-...GKK..N..NL.QDRDFENVYNLTIHHSYF...
A0A1G6J4W6_9BACI/3-239              ..............................LLYQIIVW.VT.VLG.L.S.FYV.FA....S...WRW....EE....KTRKKLGVIRKIWYALFIVGAALAWTLHPYS.lFDRWHHYVIVACVFVIIDAFIFLSAYIQRIGSSLFTID...TGHLIEQNDQVLGMQRNKLKAFFRLL.KNDAINVY....--..F.GGQ...R..AYITGVREILTKFAEKTEIEASVFPYMT..Q..............................AD..K..D...H.V..LLHFR.DRSA--...........................---VGATLERQDVY..YG.D...K...........E.K......L..VYIPVIL.QGESHVIKL...SSN..E..RL.TEFDALLFASLVAIYDL-l..
A0A2M8TGH7_9CLOT/3-260              ......................lviliyyg----VV--.--.IIY.L.I.IST.IF....Y...WID....DL....KFSLYLNKLRKTFYLIAILGVILCILSGYIN..TYDWKNLIYYMAAVVVVDIAVFETPSISKFANAEFKSNe.iMSKITSENERTFDIIENKQKVFLSII.QDAECYFE...qRN..I.GSIkifD..EYKKELLEYLNKYTNIFEIEVYMYEVKY..S..............................ND..T..D...-.L..INSIK.EVLENIiikn...................slkiRKGVLERISKNISM..GQ.IqklD...........S.K......I..HLIPIFS.GEYSYIILI...SSE..D..II.-DTDIMNVLYMVNIF---liy
A0A4Y9ABC4_9BACI/22-260             .............................k-FFIVGMW.VI.FAL.L.S.FYI.FV....Y...WRN....RE....AVKDK-DTIRKTWYLLYVLGALVYLTGNPNS.lFTSWQNYLVVLIGFIVVDSLIFLSIYVSKLGGNELQI-...PGEQIERTENYWISASGKVENMELVL.NSYEYMRY....--..T.RDE...E..EYINELDNFLNEFGEKESLFIDVLPYHT..E..............................KT..K..D...E.L..LESIQ.RPKS--...........................--KVERILDTGKTY..FS.P...K...........D.N......L..MLLPIFV.LEKSYIAKVtteIED..I..EI.QNIDGNIINILLMTYV--la.
A0A1Q2L2F5_9BACL/3-236              .............................t-FFIAGAW.LC.FLL.I.A.AYV.IL....A...GR-....RD....FRPETVSLIRKSWYGILLLGFLIYLTAEPNS.lFEDWKNYVIVLVVFAFVDSFIFLGLYIKKAGSYELDA-...VTDAITEFSESKEEDYKSVKNVHALI.NSDAVIGY....--..Y.TDE...Q..NYLAGLQGMLQQYADLEDMDISFHPYEP..A..............................GF..K..L...Q.-..FDAQE.WPLA--...........................----EANLKKMKTV..YR.S...D...........S.K......V..ALFPIEF.NRTPYILEV..vSSE..R..RV.NETDVLCMDILINVFL--lt.
A0A327RPB6_9BACI/38-298             ....................fmkmmfggva--------.LL.L--.-.L.IVI.AY....Y...WMN....SK....GYHNNLGRIRRTFYTMFLLFVIYGFISGNID..YNDWKLLTQLAALALFVDLAVFQNPNILKIWNTELKHEd.eVREALSESKKVILKNAKKVEKFSQII.QYTDVYFNd..rPI..P.VTM...H..EYKDQLKEYVELYSDTLSFSPSFFMFDS..P..............................TD..E..E...Q.K..KENIK.TQIDNIsirhaie.............fsskqedKDAMLNSFSSGETL..IL.K...E...........G.E......L..IAIPYFG.DFYSLIVTI..eSTD..G..LV.DGIDASHLLNMLVIFDW-y..
A0A0M0GFV8_SPOGL/3-239              ..............................LFFKIAVW.MI.VAC.L.G.FYV.FS....V...WKW....EK....RVKERMFAIRKTWYILYVVGAVIYWTKEPVS.iFTDWLNYLIVAIIFALVDAFIFLGSYLKRVGNNELATD...TMELLEENNDLLNSQMNKLKSFQYLL.KNEPIDIY....--..Y.GEK...E..AYIAGIEKLLADYAEKVDMKASLCKYTT..Q..............................ED..K..D...Y.L..LEHYP.DKAL--...........................---IHSRLGRKEVY..YD.A...D...........E.K......L..ALIPFSI.LEDDYVIKL...TSD..D..FV.TEFDYLLFTSLISIYDLM...
A0A4V3B125_9BACL/8-285              ......................lwvqiaig-------T.FL.VFL.I.G.VYI.IS....VinfFKV....DN....RYRENLPLYRKTLYFLFTVLICLLGMLNQIR..IDDWRYLLMAAIAVIFTDIAVLSTPTITKIWNTEFGSHd.dAKKYIQQNATNERNRKAKLNYFSQLV.QTAHFVKR....KI..A.EQG...L..SEREAFQTFLSYYPNEFGLKMVLYRMGT..R..............................SE..N..D...EaI..TEEFR.ALINRIervhslsleema..dipkedstdsrstSERAIQQVWNGTVL..AL.N...K...........E.Ee...niA..HLCPIFIrGKDSYVIFL..iEDT..G..TL.LELDPLLITDLAYIY---l..
A0A4Q0VMM2_9BACI/1-217              ............................mf--------.--.---.-.-.---.--....-...---....--....-------------------GIILAFGLREIE..YTNWQLLLQLTAFIIFVDLSVFQTPNILKIWSAEFKHAd.tIAANAKENEKRLQYMNKKSNVFTTIL.QQAEDYLTg..iSN..I.TSK...N..SYEKELKSFIWQYTSQFDFSIKIFFLPD..D.............................lED..E..D...A.V..KNEIL.IGLKQWenifnl...............sfnhskLEEAQLILNNAQVF..-A.Y...D...........G.K......H..VIIPIYD.GRYNLLMKV..tANQ..E..DI.IEIDTTNLINLTTIFNWV...
A0A0M2EE55_BACIA/3-239              ..............................LFFQLTVW.LL.LGA.L.A.VYV.FA....V...WRF....EQ....KVKEKMFAIRKTWYWIYVAGAVVYWTNDPSS.iFTDWMHYLIIAVFFALTDAFIFLSSYIKKLGNHELETD...THQLLEQNNDLLHSYLNKLKTYQYLL.KNEPIHVY....--..Y.GSV...E..AYIEGIERLIYSFADKMNIQAVLCPYDM..Q..............................EQ..K..D...D.L..LRTLD.QRAL--...........................---IQAKLDRQEVY..YD.D...F...........G.H......L..VLIPFSV.ADAHFVIKL...TSD..E..IV.TEFDYLLMTSLTTIYDL-i..
A0A419V0D0_9BACL/62-314             .........................rrksi--------.--.---.-.-.---.--....-...---....-K....WYKDNKRKFRRSLYFIFIFCIIIGLYLNLIS..FEEWLVLLVAAICIVFIDISIFNTPFVNKIGKFEFQHDn.eFNEYVEDFRKKQLQWLQKTNECSILI.QNSESAYG....-S..I.SKD...L..SVEESLRTFLDFYCTSFSINSYVYNLGE..S..............................YA..S..D...K.I..FEALT.NTIDMIskkhtinyeemv..inmennktnesdvLENIIETLYDSQFI..EL.ErysV...........E.H......Y..LLIPIYL.NETSLIILL..kSRV..N..NI.ENVDGFHIINLTYLFN--ai.
A8FC77_BACP2/3-239                  ..............................LFFQLTVW.LL.LGA.L.A.VYV.FA....V...WRF....EQ....KVKEKMFAIRKTWYWIYVAGAVVYWTNDPSS.iFTDWMHYLIIAVFFALTDAFIFLSSYIKKLGNHELETD...THQLLEQNNDLLHSYLNKLKTYQYLL.KNEPIHVY....--..Y.GSV...E..AYIEGIERLIYSFADKMNIQAVLCPYDT..Q..............................EQ..K..D...D.L..LRTLD.QRAL--...........................---IQAKLDRQEVY..YD.D...F...........G.K......L..VLIPFSV.ADDHFVIKL...TSD..D..IV.TEFDYLLMTSLTTIYDL-i..
A0A498DFG2_9BACI/3-239              .............................n-FMLAGVW.IV.FLL.L.I.IYT.TL....S...WF-....KK....DIVSNVDNIRKVWYLILILGCLIYLTNEPIS.lFTNWKNYLIVLVVFLIVDSLVFLNLYIVKLGGHELKV-...REKQVDETQGFLNVTNQKVNNMEKVV.NSYEYPKY....--..T.RSK...E..EYVQGLENFFNEYAMLELLNIDILPYRT..E..............................KE..K..E...I.V..LENTP.KGK---...........................---VERVLSINKAY..YS.S...K...........D.N......L..MLMPLWV.MDEDYVAKVstnSEE..V..GI.YDVDVNIINMLLMVYTL-a..
A0A098EZE6_9BACI/4-270              ............................tw--YMVIIF.LIlLVG.I.A.FSIcIY....I...WS-....RE....FYLKHRVGMRKIYYGLIVFVSFLLWAFGAFPdvGQNLQNLIALVISVIIIDLFVFQTPDITKFMSNELKQE..nLVESINKNQDTIVELSEKLIKVNEMM.PKSEIKWQ...vDE..FeFTP...E..KYEEYVLSYLRNFGSSFNLDVYSYHVES..S..............................SD..Q..A...I.F..KGNVE.SAYKKVlkehdft............lrgigmrnKHAIKTLLDGGNIE..IIeK...D...........R.N......A..VLFPYYG.EYYNLLFVVs.sRKE..R..VV.TGADASLMLNLLYTFDMW...
Q5WGM8_BACSK/3-239                  ..............................LLYQLLVW.LT.VLG.L.G.LYV.FA....S...WRW....EE....ETKKRLPIIRRLWYAWFVTGAAFTWTFYPES.iFTEWNHYLIVALLFVVVDAFVFLSAYVQRIGSNVFTID...TGQLIEANDQVLKAQQDRLKAFFRLL.KSDSINVY....--..Y.GGQ...R..AYITGVREILARLADKTEIQASVFPFMT..Q..............................GD..K..D...H.L..LVHFK.DRTT--...........................---VRATLERQDVY..YG.E...K...........D.K......L..VFIPVIL.QGESHVIKL...SSE..E..RL.TEFDALLFASLVAIYDL-l..
A0A060M2F0_9BACI/2-216              ..........................emgd--------.--.---.-.-.---.--....-...---....--....ATKRKLPFIRKIWYSLFTVGAALSWTLFPTS.lFENWLHYLIVACLFVVIDAFVFLSAYVQRFGSNLLTID...TGQLIETNQEVLQLQEKRLKAFFRLL.KSDTINVY....--..F.GGH...D..AYITGVREILMKFAEKTDIEANLFPFMT..K..............................AE..K..D...H.L..LFHFS.NRTV--...........................---VSATLERQDVY..YG.E...K...........D.R......L..IFIPVIL.KGEHYVIKL...SSE..E..RI.IEYDALLFASLVAIYDL-l..
A0A285D6U4_9BACI/35-280             ..............................LFFQENKW.ML.LFGfI.T.IIL.YI....S...WLF....PF....FFIKHKQNLRRTWYCLFILGIVLIINDNGFD..ETQWQRYALLAGMFIFVDLALFLTPNIKRIAGTEIESIn.eMENINEEMKKAIIQTKSRSKQFTSIL.DSIATSPFg..sQE..W.NEI...E..EYRVSLEAFLYSYGEMC--RQDITVLRK..E..............................ND..L..E...F.L..SELGT.SIGIEL...........................IEEQFNQLNEECI-..VQ.I...N...........N.Y......I..VLIPLTK.LLHPVVIVI..eSQK..D..PV.LQIDFDNIVNLSVIHSW-y..
G2TPX2_BACCO/4-240                  ..............................LFFKTFVW.LC.FAG.L.V.IYT.YL....Y...GKN....EE....KMDAKVFLIRKIWYLVYLFGALVYWTIHPAS.iFTDFKNYAITALIFAAIDGFIFLNMYFRKAGKYELER-...FTKTVSANESLIQDNLSMAKNMLDIL.NNEGIVGY....--..Y.GSK...E..GYLLGLKEVLSSYAEKADMSVNILPFTT..P..............................LE..K..D...Q.A..LYRYK.NPGS--...........................---VRAKLDRLETV..YH.V...D...........G.N......D..ALHPIYLfHDELYLLKI...SGS..R..AI.TEMDCILFVIMAHVYDF-a..
A0A3N5ZUI9_9BACL/3-280              .........................iffii-FFLTVLV.YI.FFS.L.-.---.YL....S...FIN....ID....KYVENLQMLRRFFYAIFVVGISIGLMLEKIN..LDDWKQLLELTALFVFIDLAVFQTPDILKIWNAEFKHDh.yIRKIIKKNEEIISYNSQKVECFTDIV.LNKSTNYLn.niPL..H.LKF...D..DYKEDLKKFLEFYTGTFQIDLAIFEFES..Glnanl...................edlhsnL-..-..-...-.-..--DIK.QAFTRIeqcynktivdge..wklflvqelldgkAIELHNKKEVSSSD..NF.K...D...........K.K......V..FIIPFYG.RKYDILIGI..sSTF..I..EV.DGIDASHILNLTQIFDW-y..
SP2SA_BACSU/3-239                   ..............................LFFQIMVW.CI.VAG.L.G.LYV.YA....T...WRF....EA....KVKEKMSAIRKTWYLLFVLGAMVYWTYEPTS.lFTHWERYLIVAVSFALIDAFIFLSAYVKKLAGSELETD...TREILEENNEMLHMYLNRLKTYQYLL.KNEPIHVY....--..Y.GSI...D..AYAEGIDKLLKTYADKMNLTASLCHYST..Q..............................AD..K..D...R.L..TEHMD.DPAD--...........................---VQTRLDRKDVY..YD.Q...Y...........G.K......V..VLIPFTI.ETQNYVIKL...TSD..S..IV.TEFDYLLFTSLTSIYDL-v..
#=GR SP2SA_BACSU/3-239        SS    ..............................XXXXXXXX.XX.XXX.X.X.XXX.XX....X...XXX....XX....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXH...HHHHHHHHHHHHHHHHHHHHHHHHHH.HHS-EEEE....--..E.SSH...H..HHHHHHHHHHHHHHHTTTSEEEEEE-SS..H..............................HH..H..H...H.H..HTTSS.-HHH--...........................---HHHHHHTT--E..E-.T...T...........S.S......E..EEEEEEE.TTEEEEEEE...E-S..S..--.-HHHHHHHHHHHHHHHH-H..
A0A1J6W3H6_9BACI/3-275              ...........................lkl----YIVI.LL.GFS.V.A.NLA.FF....I...FK-....PL....KYHLSLRTLRKTLYTLFIGAISLGLLLDEIQ..LSEWELILTLTAIVIFMDIAILLTPSIMKIWSAEFHYTd.yVEEIIKTNDKIHKAMVYRVEAMSEMI.QTNSELLP...fRN..Y.TD-...-..---QELRNYLDLYAAKFGFDIQIHRVPQ..Idfsagdlhhaw.......ieglaadeiemlVE..T..H...R.L..TEGIR.MTVEQIktinn.................fdfdsEEEDVEALAQSAVV..SL.I...E...........D.E......S..MLVPVFM.DTDQFIVVL..kEEI..G..EV.LEVDAIHIANLIYLF---ysl
A0A0U1NYW0_9BACI/40-286             ......................ltftqenk-------W.LI.LIG.FsA.VIL.YI....S...WAF....EA....FFKKHKQNLRKTWYFFFIVGVVLFLDHTGFN..VKEWERLTLLAAMFIFVDLALFLTPSIKKIGGAEMEQIn.eVESVNEEMKKVIIQTQNRSLQFTDIL.DMMQISSFe..tQE..W.NEI...D..SYRESLEDFLYSYGETCRQVITVFKKDN..N..............................NF..F..K...Q.E..VGTIL.G----Vn.........................lTEEQMKSINDKTVV..-H.I...N...........K.Q......I..ALIPYLE.KVFPVVISI..eSEK..E..HV.LDIDIDHIINLSLIHSWL...
A0A3E2JE45_9BACI/3-265              .........................mflnt-YFGVLIV.YV.VFT.W.-.--L.FA....I...IK-....PL....NYGIYLKLLRKTLYVLFILTLGLGIISGRVD..LNDWLFIVTVTALTVFIDLSVLMTPSILKIWRTEFQNGsefLEEMIKKNDKIQKSMVAKVGYMSVLI.QKSDLYFEd..lQI..P.ENQ...R..EYAKGLETYLEQYSDEFGLKVHIREFPTffH..............................EN..E..S...E.I..KDKIK.TELIKIdrihnf...............dfnykeIDEYIDAVYNSEII..SM.V...E...........N.D......S..MIIPIYL.ENRNIIVVL..kNDK..G..TL.LEVDGVHIANLVYLFD--sy.
A0A1H3V1Y1_9BACI/3-64               .............................t-FFITGMW.MV.FIL.L.C.LYT.YF....S...RK-....EE....FEEKHKNSVRKIWYLIYILGSMIYLTKNPNY.lMINWK---------------------------------...--------------------------.--------....--..-.---...-..----------------------------..-..............................--..-..-...-.-..-----.------...........................--------------..--.-...-...........-.-......-..-------.---------...---..-..--.------------------...
A0A0A3HM51_9BACI/2-280              ..........................afki----FILI.LL.LFV.I.G.NFI.YF....Y...KS-....QA....NYSLHLRTLRKGLYTLFIGAIGIGILIDEVD..LSNWQLILTLASIIVFIDIAILLTPSILKIFNTEFQYMd.yVENIITTNDKREKATIDRVNSMSELI.QLAGVDLI....DH..Q.TNK...R..SEIEELDSYLERYSEQYGFKIQIYELNY..SpvplselsyndkrdldedelillseqlgfvKG..I..E...T.C..LNK--.-----Ieklns................fnleenRQLYIEELSNLKIV..SL.L...N...........E.D......S..MIVPVDM.EKRQLLIVL..kNSK..G..EL.LEVDAVHIINLIYIF---yiy
W7YZW3_9BACI/3-238                  ..............................LIYQLFVW.LI.VVG.L.V.FYV.FA....S...WKW....EE....ATKRRLPLIRKCWYAAFVIGAALSWTLHPES.lFENWQHYLIVACLFAVIDAFVFLSAYVKRFGSNVFTID...TGQLIEANDEVLQNQQKRLLAFFDY-.KVTPLTSI....--..T.GGI...R..AYITGVREILMRFAEKTEVEASVFPYVT..K..............................GD..K..D...H.L..LIHFK.DRSA--...........................---VSATLERQDVY..YG.E...K...........D.K......L..IFIPVIL.QGEHHIIKL...SSE..E..RL.TEFDALLFATLVAIYDL-l..
A0A2C1ZFB9_9BACI/51-291             .........................nkwfi--------.LT.VFS.-.A.VIL.YI....S...WAF....KD....FFANHKQNLRRTWYFLFIVEVVLLLNQTGFD..VKEWQRYTLLAGMFIFIDLALFLTPSIKKIGGAEMEQIn.eVESVNEEMKKVIAQTQNRSLQFTYLL.DMIQISSFe..tQE..W.DVI...D..SYRESLEDFLFSYGETCRQEITV--FK-..-..............................KD..H..D...T.H..FKQEV.GTVLGIn.........................lTEEQMNSIDDNTVV..-H.I...N...........K.Q......T..VLIPYLE.KVFPVVISI..eSEK..E..HV.LDIDIDHIINLSLIHSWL...
A0A6I1FJJ4_9BACI/4-274              ..........................fmii-FFTFIML.FL.IAS.L.-.---.IY....F...WFY....TD....KYVENLQSIRKSYYVLAVLFLCIGLVSNQFS..LQAWQTLLSFVLIVVFIDLAVFQTPDILKIWNTEFQHSn.yIRKTIKKNQEVLGYNAKKVQNFTEVI.SKTADHFVe..rHP..P.QHL...R..QYKDDLRDYLNLYADTFQFHIAIFPFNS..T..............................YD..G..E...E.L..KRNVE.SAFNSVeicynmniiddn..irenfiqsllngqSIPLHSNSN-EQSV..LS.D...N...........K.N......I..FLVAYYG.EVFNMLIGI..sSSF..V..EV.DGIDASHILNLAQIFDW-y..
A0A0V8JCE8_9BACI/2-238              ............................iw-FFRVVVW.VV.FVG.I.G.AYL.IF....Y...WRD....EE....RAEQKLDAIRKLWYVLYIFGALIYWTGNPHS.iFTNWDHYLVVLMVFVLIDAFIFLSLYLKKIGNNELAR-...ITKSVENNQMLLDDLRAKVNNALYIL.KTEGITAY....--..Y.GSK...E..NYLYGLKLVLEAYVEKEGHSFTILPFTT..P..............................QE..K..N...E.A..LAMYS.NASL--...........................---IQSTLSRAEAY..YN.K...E...........D.N......F..AFYPFNI.EDETYVIRI...SST..A..KV.SDVDCSLMGILLATYDI-l..
A0A3S2UZB7_9BACI/38-282             .....................flqgnkwsl--------.-I.IGF.T.A.IML.YI....S...WSF....PI....FFRESKQNLRRTWYFLFIVGMILLLMDIGFK..ESEWRSYALMALMFVFVDLAIFITPNIKRIGVAEVESIn.eVESINDEMKKVIIQTKSRSKQFTTIL.DSIATESFg..tQD..W.TDI...E..DYRISLEDFLYAYGEVCRQDITV--FC-..K..............................ED..D..S...I.F..TAEVG.TTLG-Ie.........................lNEDQLNRLNEETIV..-Q.L...D...........K.K......I..VLIPFTK.LIHPVIISV..eSEK..E..PL.LQIDFDYIIDLAVIHTW-y..
A0A317L5K3_9BACI/6-291              ..........................lgfs----ILIG.IL.LLF.I.-.LYV.YIqswrS...FRN....KEd..nRFNENLYQYRKTLYFLFVLCLGILWIVQILS..IKDWQTLLILAVIVVFIDISVFSTPTIKKIWRTEFQAFd.pLKSYIQENSLLEERQKDKLNYFSQLI.QIAPLIKS....-D..I.DSR...D.lEFSEALSIFLSYYAEAFGLRIHLYQVEA..N.............................rQN..E..E...Q.P..YETID.LFIETIqiikqthtldwstmpdnlvkpdetassETIVIETLWNGDIV..AL.D...R...........E.EkhgkgmA..HLCPVFVgEDEIFLLFI..eEHH..Q..RV.YEMDALFLTNLACLFCF-f..
E6TS07_BACCJ/5-263                  ...........................flg-YFLLIIA.FL.ICS.L.-.--I.YY....G...FR-....SD....LFIENLGVIRKGFYVLFIVLLCVGFLYEAID..YTNWKLILQLTVFIIFIDIAVFQTPNMLKFWSGDQTKSe.yIEKTIKKNEETLGYNTRKVEKFMEVI.QYSSFHFYn..kTT..P.DSK...D..KYISNLKDYIRLYTDTFQFHISIFPFEV..T..............................GN..D..D...E.L..KESVR.QTFSNVekcyny..............iiediseRENIISSLSSGKSM..ML.K...Q...........D.K......L..FIVSYFG.EQYNLLICI..kSED..V..SV.DGIDASHVINLAHIFDWW...
A0A0M1NLQ7_9BACI/2-240              .............................lMFFRVFVW.VV.FIA.L.L.AYV.IL....S...WKY....KE....KVSKRIEAIRKTWYIIFILGALIYWNFYPMS.iFNEWENFLIMAIVFILIDMFVFLSMYISKIGDNELSY-...ATKAVAESDKLLTDNREKVKNMFHLL.KKEGIPEY....--..Y.QTN...K..EYLAYLSILLQAYAAKEGMNVKILPFKT..E..............................QD..K..Q...S.V..INGLP.NLNG--...........................-STIRATLEREDTY..YN.D...E...........E.K......M..ALQPVSI.LMEPYILDV...KSE..S..FV.SEVDCLLIALLIMMFDM-v..
A0A366E413_9BACI/1-208              ..............................--------.--.---.-.-.---.--....-...---....--....-------------------------------..-------------MIFIDIFVFSTPTITKIWKTEFQAYd.pLKTYIQENSFIEEKQRDKLNYFSQLI.QIAPYIKS....EI..E.LQH...N..DFLEGLGAFLNYYAEGFGLCIHLYNVET..V..............................ADqsE..D...E.R..MNEFL.DTIHRIkqthtldwlcm....ldnldvqgdsdaEEVVIDNLWSGEIV..AL.D...R...........E.EkhgkgmS..HLCPIFVgDDYIFILFI..eEIY..Q..RI.YEIDALFITNLAFLYCY-l..
I8UEB9_9BACI/6-268                  ........................lmilcf-------S.LL.LLG.I.A.CSI.GL....Y...IWN....RH....YYLKHRVAIRKIYYGVSVGMFFLFWTYNAYP..TFKLEYLIALGISVVIIDLFVFQTPDITKFMSNELKQE..sLVESINKNRGTFIELSEKLIKVNEMM.PKSNMTWH...vEE..FqFTP...E..KYEEFVLSYLRNFAAS--FQLDVYSYMV..A..............................SS..P..D...P.VifQRHIE.GAYEEIlkdhdft............tkgvgmrkKQAIKTLLDGENIE..IL.E...K...........EcS......S..VLFPYFG.EYYNILFVVr.sRKN..S..EI.TGADASLMLNLLYTLDLW...
A0A1B9B080_9BACI/1-264              .........................mfgki-----YIAiLV.CFS.L.V.SCM.MA....I...VK-....PS....IFDLHLKNFRRSLYTLFVLCLGIGIIAGGIN..ITNWTYILSLTAIVVFIDLSVLLTPSILKIWQAEFITGsefLEATIKENEKIQRATVTKVEHMSLLV.QDAIYYFEq..kPV..P.ENG...E..EYERELKKYLVLYCEEFGLSVDINQYEA..D..............................DS..I..DldiS.V..RERIK.QKLIRIdhihnf...............dfnqqlLQSFTDSIFNLEVI..TL.E...D...........H.D......A..LLIPIHL.QMYNFIIVL...KKD..K..GIpIEVDGVHIANLVHIYD--sf.
A0A1I4KPU8_9BACI/7-288              .....................visiligvl--------.-L.LFI.L.F.VYV.RS....L...RSFsnkeDN....RFNENLYQYRKTLYVLFVLSIGTLWLAEVIS..IDDWQRLVILAGMAVFIDIFVFTTPTIKKIWKTEFQAYd.pLKTYIQENSLIEEKQQDKLNYFSQLL.QIAPFIKS....DI..E.KKQ...L..NFPESLDLFLCYYADTFGLRVHLYEVKA..K..............................-D..I..E...I.E..HEPIE.VFIKTIqtikqthtldwgs.mpvnlavndegntERLIMETLWNGDIV..AL.D...R...........E.EkhgkgmA..HICPIFVgENHTFILFI..eEIH..Q..RV.YEIDAMFITNLACLFCF-l..
S2XV84_9BACL/43-288                 .......................sftqknk-------W.FI.LIG.F.AaVIL.YI....S...WAF....EG....FFKKHKQNLRRTWYFLFIIGVVLLLNQTGFN..VQEWQRYTLLAGMFIFVDLALFLTPTIKKIGGAEMEQIn.dVESINEEMQKVIVQTQNRSLQFTDIL.DRMQISSFe..tQE..W.NEI...E..NYQESLEDFLYSYGET--CRQNITVFKK..N..............................ND..N..F...F.R..QEVGT.ILGVNI...........................TDEQMNSINEK-VV..VH.I...D...........K.H......T..VLIPYLE.KIFPVVISI..eSEK..E..HV.LDIDIDHIINLSMIHSWL...
A0A1H3V2F0_9BACI/1-176              .............................m--------.--.---.-.-.---.--....-...---....--....-------------------------------..-------LILLIVFVIIDSLFFLNLYISKLGGQELQST...ITQ-VGVTQKELDATRRKMAHVPQIL.ICFNFPLY....--..N.VSK...D..AYIDNMERLLKEYAQKESLVIDLIPFGT..K..............................KE..R..E...A.F..LDTMG.TNKD--...........................--KVRRFLRHKNSF..TS.S...K...........D.N......L..ALYPFEI.LDYPYVVQV..qTTD..DklKI.TEDDGNAITTLIIAYC--la.
#=GC SS_cons                        ..............................XXXXXXXX.XX.XXX.X.X.XXX.XX....X...XXX....XX....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXH...HHHHHHHHHHHHHHHHHHHHHHHHHH.HHS-EEEE....--..E.SSH...H..HHHHHHHHHHHHHHHTTTSEEEEEE-SS..H..............................HH..H..H...H.H..HTTSS.-HHH--...........................---HHHHHHTT--E..E-.T...T...........S.S......E..EEEEEEE.TTEEEEEEE...E-S..S..--.-HHHHHHHHHHHHHHHH-H..
#=GC seq_cons                       .............................h.....hhh.hl.hhh.l.h.hhl.hh....h...at.....pp....thtpph.tlRKsaYhlFllshhlhhhhpshs..hssWphhlhlsshhlhlDlhlF.oPsIpKlhssEhppt...lpphlpcNcchlpppppKlpphspll.ppsshhhh........h.tsh...c..pYhpsLcpaLptYu-phshplslh.aps..p..............................p-..p..-...p.h..hpplp.pthp.l.............................tlhspLpptcsh..hh.p...c...........c.c......h..hllPhhh.pthshlltl..pspc..s..pl.h-lDs.hlhsLhhlash.h..
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