#=GF ID TBX2-3_RD
#=GF AC PF20627.3
#=GF DE T-box transcription factor 2/3, repressor domain
#=GF AU Chuguransky S;0000-0002-0520-0736
#=GF SE PF12598
#=GF GA 20.00 20.00;
#=GF TC 20.00 20.00;
#=GF NC 19.90 19.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 8 -Z 90746521 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 30599067
#=GF RT Transcriptional repression of the ectodomain sheddase ADAM10 by
#=GF RT TBX2 and potential implication for Alzheimer's disease.
#=GF RA Reinhardt S, Schuck F, Stoye N, Hartmann T, Grimm MOW,
#=GF RA Pflugfelder G, Endres K;
#=GF RL Cell Mol Life Sci. 2019;76:1005-1025.
#=GF RN [2]
#=GF RM 29726930
#=GF RT Functional variants in TBX2 are associated with a syndromic
#=GF RT cardiovascular and skeletal developmental disorder.
#=GF RA Liu N, Schoch K, Luo X, Pena LDM, Bhavana VH, Kukolich MK,
#=GF RA Stringer S, Powis Z, Radtke K, Mroske C, Deak KL, McDonald MT,
#=GF RA McConkie-Rosell A, Markert ML, Kranz PG, Stong N, Need AC, Bick
#=GF RA D, Amaral MD, Worthey EA, Levy S, Wangler MF, Bellen HJ, Shashi
#=GF RA V, Yamamoto S;
#=GF RL Hum Mol Genet. 2018;27:2454-2465.
#=GF DR INTERPRO; IPR048387;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This is the repressor domain (RD) found at the C-terminal of
#=GF CC T-box transcription factors 2 and 3 [1,2].
#=GF SQ 1428
#=GS A0A0P7XP71_SCLFO/503-608 AC A0A0P7XP71.1
#=GS A0A3P9PL67_POERE/502-611 AC A0A3P9PL67.1
#=GS A0A7L1P9Q2_ORIOR/532-632 AC A0A7L1P9Q2.1
#=GS A0A4W4HHT4_ELEEL/495-595 AC A0A4W4HHT4.2
#=GS A0A7L0U4N1_CHOAC/536-640 AC A0A7L0U4N1.1
#=GS A0A7K8A7Y5_9PASE/513-621 AC A0A7K8A7Y5.1
#=GS A0A8D2HLA1_UROPR/484-592 AC A0A8D2HLA1.1
#=GS A0A7F8RV86_LEPWE/310-427 AC A0A7F8RV86.1
#=GS A0A6J2ZYA4_VICPA/378-481 AC A0A6J2ZYA4.1
#=GS B0R122_DANRE/509-613 AC B0R122.1
#=GS A0A7K4UGK3_9SYLV/513-623 AC A0A7K4UGK3.1
#=GS A0A7K6KIS9_9PASE/546-650 AC A0A7K6KIS9.1
#=GS A0A4U5V908_COLLU/528-628 AC A0A4U5V908.1
#=GS A0A2K5IDC1_COLAP/532-640 AC A0A2K5IDC1.1
#=GS A0A384BGL7_BALAS/397-514 AC A0A384BGL7.1
#=GS A0A5J5CQT7_9PERO/526-626 AC A0A5J5CQT7.1
#=GS A0A851CX90_CALVR/202-298 AC A0A851CX90.1
#=GS M3ZT55_XIPMA/527-627 AC M3ZT55.2
#=GS A0A8C4NH72_EPTBU/430-546 AC A0A8C4NH72.1
#=GS A0A8T2PR53_9TELE/529-629 AC A0A8T2PR53.1
#=GS A0A7K8J2K1_9PASS/513-621 AC A0A7K8J2K1.1
#=GS A0A498MDT7_LABRO/458-562 AC A0A498MDT7.1
#=GS A0A2K6QKE6_RHIRO/552-660 AC A0A2K6QKE6.1
#=GS A0A3P8UXS1_CYNSE/502-608 AC A0A3P8UXS1.1
#=GS A0A8C8LRV1_ONCTS/528-627 AC A0A8C8LRV1.2
#=GS A0A8D2L234_VARKO/514-621 AC A0A8D2L234.1
#=GS A0A493TF68_ANAPP/20-128 AC A0A493TF68.1
#=GS U3JSE1_FICAL/561-608 AC U3JSE1.2
#=GS A0A218V2P6_9PASE/546-650 AC A0A218V2P6.1
#=GS A0A2U3X448_ODORO/536-644 AC A0A2U3X448.1
#=GS A0A851B4Q8_PICGY/513-621 AC A0A851B4Q8.1
#=GS A0A7L3XW68_9AVES/546-650 AC A0A7L3XW68.1
#=GS A0A8K1LJ00_9PASS/489-598 AC A0A8K1LJ00.1
#=GS A0A667I6I4_LYNCA/554-662 AC A0A667I6I4.1
#=GS A0A6P3VSV2_CLUHA/534-638 AC A0A6P3VSV2.1
#=GS A0A340XVR6_LIPVE/555-654 AC A0A340XVR6.1
#=GS A0A3L8S4H6_CHLGU/513-621 AC A0A3L8S4H6.1
#=GS A0A7L2VCS2_9AVES/513-621 AC A0A7L2VCS2.1
#=GS H3DA71_TETNG/505-612 AC H3DA71.1
#=GS G1QHU7_NOMLE/485-576 AC G1QHU7.2
#=GS A0A401SIK6_CHIPU/522-628 AC A0A401SIK6.1
#=GS A0A8C4RXQ5_ERPCA/506-612 AC A0A8C4RXQ5.1
#=GS A0A2I0LYP3_COLLI/489-537 AC A0A2I0LYP3.1
#=GS A0A1S3A9K0_ERIEU/402-515 AC A0A1S3A9K0.1
#=GS A0A673B5G7_9TELE/502-608 AC A0A673B5G7.1
#=GS A0A1S3LJB6_SALSA/534-633 AC A0A1S3LJB6.1
#=GS A0A9W3GQ39_CAMBA/261-350 AC A0A9W3GQ39.1
#=GS A0A7L1NDI4_RHICY/513-621 AC A0A7L1NDI4.1
#=GS A0AA40HHG3_CNENI/656-699 AC A0AA40HHG3.1
#=GS A0A7J8GH19_ROUAE/525-641 AC A0A7J8GH19.1
#=GS A0A5N4C8Q9_CAMDR/554-662 AC A0A5N4C8Q9.1
#=GS A0A851YDN9_9AVES/513-621 AC A0A851YDN9.1
#=GS A0A8C5YXN7_MARMA/521-629 AC A0A8C5YXN7.1
#=GS A0A9D3SJX2_9TELE/509-614 AC A0A9D3SJX2.1
#=GS A0A7K7H3K0_ERIRU/537-641 AC A0A7K7H3K0.1
#=GS A0A2I4D7H9_AUSLI/420-527 AC A0A2I4D7H9.1
#=GS A0A7L2IBQ1_9PICI/513-621 AC A0A7L2IBQ1.1
#=GS E1BK57_BOVIN/535-642 AC E1BK57.3
#=GS A0A0N8K2K8_SCLFO/527-626 AC A0A0N8K2K8.1
#=GS A0A7K9BMK1_9PICI/537-641 AC A0A7K9BMK1.1
#=GS A0A8C3LCW3_CHRPC/512-621 AC A0A8C3LCW3.1
#=GS A0A8C6A0V8_MARMA/484-596 AC A0A8C6A0V8.1
#=GS A0A667WT94_9TELE/500-607 AC A0A667WT94.1
#=GS A0A8C6E610_MOSMO/555-662 AC A0A8C6E610.1
#=GS A0A7L0F1V6_CORCN/513-621 AC A0A7L0F1V6.1
#=GS A0A7L3MPQ0_9PASS/171-279 AC A0A7L3MPQ0.1
#=GS A0A7J7FMI0_DICBM/554-662 AC A0A7J7FMI0.1
#=GS A0A286XLX3_CAVPO/499-615 AC A0A286XLX3.1
#=GS A0A2K6CZN0_MACNE/401-517 AC A0A2K6CZN0.1
#=GS A0A7K8J5H1_9PASS/546-650 AC A0A7K8J5H1.1
#=GS A0A3Q1IWZ4_ANATE/521-621 AC A0A3Q1IWZ4.2
#=GS A0A7K4S4S3_COLPI/359-405 AC A0A7K4S4S3.1
#=GS A0A665WQZ9_ECHNA/502-609 AC A0A665WQZ9.1
#=GS A0A7J5YCS1_DISMA/493-601 AC A0A7J5YCS1.1
#=GS A0A7L2I3L0_SAGSE/507-630 AC A0A7L2I3L0.1
#=GS A0A7J8C028_MOLMO/534-642 AC A0A7J8C028.1
#=GS A0A8B9YXR0_9AVES/25-99 AC A0A8B9YXR0.1
#=GS A0A8C6G9K6_MUSSI/530-638 AC A0A8C6G9K6.1
#=GS A0A9Y4KKI8_9TELE/528-628 AC A0A9Y4KKI8.1
#=GS A0AAD9CDM4_DISEL/493-601 AC A0AAD9CDM4.1
#=GS H2T7W6_TAKRU/494-605 AC H2T7W6.2
#=GS A0A3Q0FQS0_ALLSI/528-628 AC A0A3Q0FQS0.1
#=GS A0A9J8BLM7_CYPCA/455-548 AC A0A9J8BLM7.1
#=GS G3QAB6_GASAC/482-580 AC G3QAB6.2
#=GS A0A6F9A8H9_9TELE/479-572 AC A0A6F9A8H9.1
#=GS A0A3Q1HGC3_ANATE/502-609 AC A0A3Q1HGC3.1
#=GS A0A091RJI6_9AVES/194-305 AC A0A091RJI6.1
#=GS A0A1U7QTY4_MESAU/503-611 AC A0A1U7QTY4.1
#=GS A0A9Y4JNY6_9TELE/504-611 AC A0A9Y4JNY6.1
#=GS A0AA40KZS6_PYGPA/513-621 AC A0AA40KZS6.1
#=GS A0A212D6V7_CEREH/18-129 AC A0A212D6V7.1
#=GS A0A8M1F4H7_URSMA/554-662 AC A0A8M1F4H7.1
#=GS A0A1S3T011_SALSA/521-626 AC A0A1S3T011.1
#=GS A0A7K9YP68_9GALL/546-650 AC A0A7K9YP68.1
#=GS A0A8C5WUV2_LATLA/20-115 AC A0A8C5WUV2.1
#=GS A0A8C4YXU8_GADMO/519-628 AC A0A8C4YXU8.2
#=GS A0A3P9AWG3_9CICH/502-609 AC A0A3P9AWG3.1
#=GS A0A7K9UP22_ANSSE/533-622 AC A0A7K9UP22.1
#=GS A0A2K5DXA5_AOTNA/552-660 AC A0A2K5DXA5.1
#=GS A0A2K6NGR8_RHIRO/524-641 AC A0A2K6NGR8.1
#=GS A0A8C5U8P1_9PASS/513-621 AC A0A8C5U8P1.1
#=GS A0A2Y9LAD4_DELLE/534-642 AC A0A2Y9LAD4.1
#=GS A0A3Q3AQK2_KRYMA/484-585 AC A0A3Q3AQK2.1
#=GS A0A7L0LY38_9PSIT/546-650 AC A0A7L0LY38.1
#=GS A0A671UFQ3_SPAAU/475-574 AC A0A671UFQ3.1
#=GS A0A7K5APE1_9FURN/546-650 AC A0A7K5APE1.1
#=GS A0A7K9PYS9_9CORV/513-621 AC A0A7K9PYS9.1
#=GS A0A671EXU2_RHIFE/554-662 AC A0A671EXU2.1
#=GS A0A8C5P7J9_9ANUR/531-626 AC A0A8C5P7J9.1
#=GS A0A9L0JHY5_EQUAS/528-642 AC A0A9L0JHY5.1
#=GS A0A852L8H6_UROIN/513-621 AC A0A852L8H6.1
#=GS A0A7K4KTL4_9AVES/544-630 AC A0A7K4KTL4.1
#=GS A0A498LSI3_LABRO/390-488 AC A0A498LSI3.1
#=GS A0A2U9B914_SCOMX/594-697 AC A0A2U9B914.1
#=GS A0A9R1SF43_CYPCA/512-610 AC A0A9R1SF43.1
#=GS A0A3Q3ESL1_9LABR/417-521 AC A0A3Q3ESL1.1
#=GS A0A3N0Z4E8_ANAGA/510-617 AC A0A3N0Z4E8.1
#=GS A0A8C3N1J3_GEOPR/546-650 AC A0A8C3N1J3.2
#=GS A0A7K4YZ66_BUCAB/546-650 AC A0A7K4YZ66.1
#=GS A0A383ZYC3_BALAS/479-587 AC A0A383ZYC3.1
#=GS A0A7L3ZCT7_FREGA/511-619 AC A0A7L3ZCT7.1
#=GS A0AAZ1XIQ0_OREAU/453-560 AC A0AAZ1XIQ0.1
#=GS A0A7L1T102_ARAGA/558-662 AC A0A7L1T102.1
#=GS A0A7K8X0V2_9PICI/513-621 AC A0A7K8X0V2.1
#=GS A0A835U120_9PASS/258-362 AC A0A835U120.1
#=GS A0A8K1G465_9PASS/517-621 AC A0A8K1G465.1
#=GS A0A7L0Q2H5_9AVES/546-667 AC A0A7L0Q2H5.1
#=GS H0V224_CAVPO/549-617 AC H0V224.2
#=GS G1QH79_NOMLE/532-640 AC G1QH79.2
#=GS A0A4W3K6E1_CALMI/524-629 AC A0A4W3K6E1.1
#=GS A0A850U284_GRUAM/507-615 AC A0A850U284.1
#=GS A0A3M0KI20_HIRRU/462-570 AC A0A3M0KI20.1
#=GS A0A8C3G9P4_CYCLU/473-571 AC A0A8C3G9P4.1
#=GS A0A8C8YF69_PROSS/533-641 AC A0A8C8YF69.1
#=GS A0A2I3T7H8_PANTR/552-660 AC A0A2I3T7H8.1
#=GS A0A8J7TFA5_ATRSP/528-630 AC A0A8J7TFA5.1
#=GS A0A6F9CHF6_9TELE/388-493 AC A0A6F9CHF6.1
#=GS A0A8C8BZ43_ONCTS/500-605 AC A0A8C8BZ43.1
#=GS A0A2K5DX79_AOTNA/532-640 AC A0A2K5DX79.1
#=GS A0A2Y9DQD3_TRIMA/534-642 AC A0A2Y9DQD3.1
#=GS A0AAD5AHE9_SILAS/23-122 AC A0AAD5AHE9.1
#=GS A0A7L3LWP8_9CHAR/535-572 AC A0A7L3LWP8.1
#=GS A0A6J3EV96_SAPAP/552-660 AC A0A6J3EV96.1
#=GS A0A7J5YHU9_DISMA/568-665 AC A0A7J5YHU9.1
#=GS A0A7L1JZA8_RYNNI/547-651 AC A0A7L1JZA8.1
#=GS A0A2K5IDK5_COLAP/552-660 AC A0A2K5IDK5.1
#=GS A0A851A8J6_SULDA/482-590 AC A0A851A8J6.1
#=GS A0A851LDZ8_CORCR/513-621 AC A0A851LDZ8.1
#=GS A0A6P8VEJ0_GYMAC/495-603 AC A0A6P8VEJ0.1
#=GS A0A7L2CU01_CATFU/513-621 AC A0A7L2CU01.1
#=GS A0A7L2YD39_JACJC/512-620 AC A0A7L2YD39.1
#=GS A0A667Y7I1_9TELE/528-628 AC A0A667Y7I1.1
#=GS A0A7L0TJK1_PODPO/546-583 AC A0A7L0TJK1.1
#=GS A0A6J3E065_AYTFU/413-515 AC A0A6J3E065.1
#=GS A0A091W2A3_NIPNI/519-559 AC A0A091W2A3.1
#=GS A0AAD8YXQ8_9TELE/531-630 AC A0AAD8YXQ8.1
#=GS A0A7K8MGS0_9CORV/546-650 AC A0A7K8MGS0.1
#=GS A0A7K5V1H6_9CORV/513-621 AC A0A7K5V1H6.1
#=GS A0A7L1RXV6_9PASS/514-623 AC A0A7L1RXV6.1
#=GS A0A7L0LBI8_9SYLV/513-621 AC A0A7L0LBI8.1
#=GS A0A6J2MA78_9CHIR/524-640 AC A0A6J2MA78.1
#=GS A0A851AQG4_SULDA/546-646 AC A0A851AQG4.1
#=GS A0A8C8GT08_ONCTS/515-619 AC A0A8C8GT08.2
#=GS A0A9N7UCA8_PLEPL/1-64 AC A0A9N7UCA8.1
#=GS A0AAE0UKB5_9TELE/523-624 AC A0AAE0UKB5.1
#=GS A0A9Q1DQ41_CONCO/515-619 AC A0A9Q1DQ41.1
#=GS F6RTB6_HORSE/534-642 AC F6RTB6.3
#=GS A0A8B7RCA7_HIPAR/534-642 AC A0A8B7RCA7.1
#=GS A0A3Q3FZP0_9LABR/573-673 AC A0A3Q3FZP0.1
#=GS A0A2P4S5F2_BAMTH/197-301 AC A0A2P4S5F2.1
#=GS A0A1S3NRQ9_SALSA/510-612 AC A0A1S3NRQ9.1
#=GS A0A7L1GA86_9PICI/546-650 AC A0A7L1GA86.1
#=GS A0A096P4Y6_PAPAN/525-641 AC A0A096P4Y6.3
#=GS A0A6P8S1T2_GEOSA/521-623 AC A0A6P8S1T2.1
#=GS A0A6J2R1V8_COTGO/481-580 AC A0A6J2R1V8.1
#=GS A0A8C4NG13_EPTBU/490-606 AC A0A8C4NG13.1
#=GS A0A7J7EK23_DICBM/526-643 AC A0A7J7EK23.1
#=GS A0A1S3WJ78_ERIEU/553-661 AC A0A1S3WJ78.1
#=GS A0A7K9ZUX6_9CORV/548-652 AC A0A7K9ZUX6.1
#=GS A0A3P9MX42_POERE/456-558 AC A0A3P9MX42.1
#=GS A0A0D9R0V4_CHLSB/401-517 AC A0A0D9R0V4.1
#=GS A0A669E2C1_ORENI/533-633 AC A0A669E2C1.1
#=GS A0A7K8AQW9_9CORV/527-635 AC A0A7K8AQW9.1
#=GS A0A851QL83_ANHAN/304-412 AC A0A851QL83.1
#=GS A0A3N0XXM7_ANAGA/499-601 AC A0A3N0XXM7.1
#=GS A0A8M1MSQ1_NEOSC/556-664 AC A0A8M1MSQ1.1
#=GS A0A7L0XBR1_TYRSA/546-650 AC A0A7L0XBR1.1
#=GS A0A8D0FIM7_STROC/513-621 AC A0A8D0FIM7.1
#=GS F1RKD4_PIG/554-662 AC F1RKD4.1
#=GS A0A7L0M7D5_9PSIT/513-621 AC A0A7L0M7D5.1
#=GS A0A7L0QDH9_SETKR/553-657 AC A0A7L0QDH9.1
#=GS A0A2K5XDI3_MANLE/552-660 AC A0A2K5XDI3.1
#=GS A0A6P9AXS9_PANGU/518-556 AC A0A6P9AXS9.1
#=GS A0A3B4H832_9CICH/502-609 AC A0A3B4H832.1
#=GS A0A093H4B3_DRYPU/535-639 AC A0A093H4B3.1
#=GS A0A4D9EQY0_9SAUR/494-598 AC A0A4D9EQY0.1
#=GS A0A6P7IZB0_9TELE/419-484 AC A0A6P7IZB0.1
#=GS A0A3Q3M8H2_9TELE/521-621 AC A0A3Q3M8H2.2
#=GS A0A673M9E7_9TELE/498-602 AC A0A673M9E7.1
#=GS A0A7L1AAS8_GYMTI/546-650 AC A0A7L1AAS8.1
#=GS A0A670JKT2_PODMU/524-632 AC A0A670JKT2.1
#=GS A0A6G1QH62_9TELE/513-613 AC A0A6G1QH62.1
#=GS E1BLY0_BOVIN/525-642 AC E1BLY0.2
#=GS A0A3Q1GVC5_9TELE/459-563 AC A0A3Q1GVC5.1
#=GS A0A7L3EEZ0_9PASS/546-650 AC A0A7L3EEZ0.1
#=GS A0A7J6D304_9TELE/509-613 AC A0A7J6D304.1
#=GS A0A8T0ADE8_SILME/534-633 AC A0A8T0ADE8.1
#=GS A0A7K6HRH6_9PASS/513-621 AC A0A7K6HRH6.1
#=GS A0A8C5KVH6_JACJA/505-621 AC A0A8C5KVH6.1
#=GS A0A6I9N1G6_9TELE/486-594 AC A0A6I9N1G6.1
#=GS A0A0P7UHK7_SCLFO/528-629 AC A0A0P7UHK7.1
#=GS A0A8C7ZP17_9TELE/20-107 AC A0A8C7ZP17.1
#=GS A0A7J5ZTM9_AMEME/513-614 AC A0A7J5ZTM9.1
#=GS A0A7L2CRH1_CATFU/546-650 AC A0A7L2CRH1.1
#=GS A0A7L2AJF8_9GRUI/539-644 AC A0A7L2AJF8.1
#=GS A0A3Q1ERK0_9TELE/502-609 AC A0A3Q1ERK0.1
#=GS A0A1S3WII7_ERIEU/533-641 AC A0A1S3WII7.1
#=GS A0A8C7GD58_ONCKI/533-632 AC A0A8C7GD58.1
#=GS A0A8C3WTP3_9CETA/525-643 AC A0A8C3WTP3.1
#=GS A0A7K4R153_9TYRA/513-621 AC A0A7K4R153.1
#=GS A0A8C4LNT3_EQUAS/554-662 AC A0A8C4LNT3.1
#=GS A0A671YKC7_SPAAU/532-633 AC A0A671YKC7.1
#=GS A0A3Q2W0Y7_HAPBU/476-580 AC A0A3Q2W0Y7.1
#=GS A0AAD4TY02_OVIAM/535-642 AC A0AAD4TY02.1
#=GS A0A6P8U094_GYMAC/532-629 AC A0A6P8U094.1
#=GS A0A9X9M8K8_GULGU/423-530 AC A0A9X9M8K8.1
#=GS A0A8C7JIB6_ONCKI/511-615 AC A0A8C7JIB6.1
#=GS A0A8B8V377_BALMU/554-662 AC A0A8B8V377.1
#=GS A0A8T3E6K8_9TELE/529-629 AC A0A8T3E6K8.1
#=GS A0A7K6WP60_STECA/252-356 AC A0A7K6WP60.1
#=GS A0A7J8H788_ROUAE/534-642 AC A0A7J8H788.1
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A0A0P7XP71_SCLFO/503-608 .....................................GAGGLEN.G.S.L.A.-..G..Q........G....S.....A..S..TP.......TPFP..F.H.LS.QH..............ML...............A.S....Q.GIP.M...PTFG..GLFPYPYTYMA....AAAAA....A.SA....LP..TSTA..AT..........SLS......R.N....PFL....S..SS.RPRLRFSPYQI.P..VS.I.PQST.....NLLTTGL............................................
A0A3P9PL67_POERE/502-611 .....................................GASGLEN.G.S.L.S.-..T..Q........G....T.....G..G..TP.......NPFP..F.H.LS.QH..............ML...............A.S....Q.GIP.M...PPFG..GLFPYPYTYMA....AAAAA....A.SAsasvLP..ATST..SS..........PLS......R.N....PFL....G..SS.RPRLRFNPYQL.P..VS.L.PQSS.....SLLTTGL............................................
A0A7L1P9Q2_ORIOR/532-632 .....................................GVSGLDN.T.V.M.A.T..A..A.......aQ....G.....L..S..GAs.....aAALP..F.H.LQ.QH..............VL...............A.S....Q.GLA.M...SPFG..SLFPYPYTYMA....AADAA....-.--....--..----..SS..........TVH......R.P....PFL....S..AV.RPRLRYSPYPL.P..VP.L.PDGS.....SLLTTAL............................................
A0A4W4HHT4_ELEEL/495-595 .....................................GTSGLEN.G.G.L.S.-..-..P........Q....G.....T..G..AS.......GSFP..F.H.LS.QH..............ML...............A.S....Q.GIS.M...PPFG..SLLPYPYTYMA....AAAAA....A.SS....LP..AGSV..AS..........SLH......R.N....PFL....S..SA.RPRLRFSPYQI.P..--.-.-QGS.....GLLATGL............................................
A0A7L0U4N1_CHOAC/536-640 .....................................GVSGLDN.T.V.M.A.T..A..A.......aQ....G.....L..S..GAs.....aAALP..F.H.LQ.QH..............VL...............A.S....Q.GLA.M...SPFG..SLFPYPYTYMA....AAAAA....-.--....--..SSAA..SS..........SVP......R.H....PFL....S..AV.RPRLRYSPYPL.P..VP.L.PDGS.....SLLTTAL............................................
A0A7K8A7Y5_9PASE/513-621 ...................................gg--GSLEN.G.A.L.S.S..A..P........G....A.....A..G..TA.......TPFP..F.H.LS.QH..............ML...............A.S....Q.GIP.M...PTFG..GLFPYPYTYMA....AAAAA....A.SA....MP..ATSA..AAa........gPLS......R.N....PFL....G..SS.RPRLRFSPYQL.P..VT.I.PPST.....NLLTTGL............................................
A0A8D2HLA1_UROPR/484-592 .....................................GVSGLES.S.A.M.A.S..A..A........A....Aq...gL..SgaSA.......ATLP..F.H.LQ.QH..............VL...............A.S....Q.GLA.M...SPFG..SLFPYPYTYMA....AAAAA....S.SA....--..--AA..SS..........SVH......R.H....PFLs..lN..SM.RPRLRYSPYSI.P..VP.V.PDSS.....SLLATAL............................................
A0A7F8RV86_LEPWE/310-427 ................................ggpga-ATGLDA.G.G.L.G.P..A..A........S....A.....A..S..TA.......APFP..F.H.LS.QH..............ML...............A.S....Q.GIP.M...PTFG..GLFPYPYTYMA....AAAAA....A.SA....LP..ATSA..AAaaa...aaagSLS......R.S....HFL....G..SA.RPRLRFSPYQI.P..VT.L.PPGA.....SLLTTGL............................................
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A0A6F9A8H9_9TELE/479-572 .....................................GVCTMGT.A.G.IpV.S..S..V........Q....G.....V..S..GT.......SGLP..L.N.FQ.QH..............AM...............A.S....Q.GLT.V...SPFG..GIFPYPYSYLA....ATAAL....-.--....--..STKA..ST..........---......-.-....---....-..PV.RLRTRFKPYSI.P..NS.A.PDNC.....S------tpptsi......................................
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A0A9L0JHY5_EQUAS/528-642 ..................................gtp--TGLDA.G.G.L.G.P..A..A........S....A.....A..S..TA.......APFP..F.H.LS.QH..............ML...............A.S....Q.GIP.M...PTFG..GLFPYPYTYMA....AAAAA....A.SA....LP..ATSA..AAaaa...aaagSLS......R.S....PFL....G..SA.RPRLRFSPYQI.P..VT.I.PPST.....SLLTTGL............................................
A0A852L8H6_UROIN/513-621 ...................................gg--GSLEN.G.A.I.S.S..A..P........G....A.....A..G..AA.......TPFP..F.H.LS.QH..............ML...............A.S....Q.GIP.M...PTFG..GLFPYPYTYMA....AAAAA....A.SA....VP..ATSA..AAa........gPLS......R.N....PFL....G..SS.RPRLRFSPYQL.P..VT.I.PPST.....NLLTTGL............................................
A0A7K4KTL4_9AVES/544-630 .....................................GVTGLDS.T.V.M.A.T..A..A.......aQ....G.....L..S..GAs.....aAALP..F.H.LQ.QH..............VL...............A.S....Q.GLA.M...SPFG..SLFPYPYTYMA....AAAAA....-.--....--..SSAA..SS..........SVH......R.H....PFL....S..AV.RPRLRYSP---.-..--.-.----.....-------............................................
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A0A2U9B914_SCOMX/594-697 ..................................gen---ELEN.G.G.Q.S.-..-..P........H....S.....V..T..SP.......SPFM..F.H.LS.QQ..............ML...............A.S....Q.GLS.L...SPFG..GLLSYPYRYVA....APSAM....T.AA....LP..TSSA..TA..........SLT......R.S....HCF....R..SS.RPWLRFSPYHI.P..AC.A.ASSQ.....SLLA---dr..........................................
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A0A3Q3ESL1_9LABR/417-521 ..................................gvn---NPEN.G.G.F.S.-..-..S........Q....S.....F..T..SA.......SPFM..F.H.LS.QH..............ML...............A.S....Q.GIP.L...SPFG..GLLSYPYRYMA....APAAI....A.PA....LP..TCSA..TS..........TLA......R.N....HCF....R..SH.QPWLRFNPYQI.P..TS.A.ASCQ.....NLLTTG-s...........................................
A0A3N0Z4E8_ANAGA/510-617 .....................................GAGGLEN.G.S.L.S.-..A..Q........G....T.....G..S..TT.......SPFP..F.H.LS.QH..............ML...............A.S....Q.GIP.M...PTFG..GLFPYPYTYMA....AAAAA....A.SA....LP.aSSSA..AS..........SLS......R.N....PFL....S..SSaRPRLRFNPYQL.P..VS.I.PQST.....NLLTTGL............................................
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A0A4W5LZY9_9TELE/479-572 .....................................GVCAMGT.A.G.I.PaS..S..L........Q....R.....V..S..GT.......SGLP..V.N.FQ.QH..............AM...............A.S....Q.GLT.V...SPIG..GIFPYPYSYLA....AAAPH....-.--....--..-SNT..AS..........T--......-.-....---....-..PV.CPRTRFRPYSI.P..NS.V.PDNC.....ST-----pltsi.......................................
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A0A672RHB9_SINGR/516-614 .....................................GVSSMDT.S.S.M.P.S..P..S........Q....S.....L..T..G-.......TPLP..F.H.LQ.QH..............VL...............A.S....Q.GLA.L...SPFG..GLFPYPYTYMA....AAAAA....-.--....--..SSVA..SS..........SVH......R.H....PFL....N..AV.RPRLRYSPYSL.P..-S.V.PDST.....-LLTTAV............................................
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A0A3Q3ESD6_9LABR/451-555 ..................................gvn---NPEN.G.G.F.S.-..-..S........Q....S.....F..T..SA.......SPFM..F.H.LS.QH..............ML...............A.S....Q.GIP.L...SPFG..GLLSYPYRYMA....APAAI....A.PA....LP..TCSA..TS..........TLA......R.N....HCF....R..SH.QPWLRFNPYQI.P..TS.A.ASCQ.....NLLTTG-s...........................................
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A0A9D3RVQ8_ANGAN/515-619 .....................................GASGLEN.G.S.L.S.-..-..A........Q....S.....A..G..TP.......NPFP..F.H.LS.QH..............ML...............A.S....Q.GIP.M...PTFG..GLFPYPYTYMA....AAAAA....A.SA....LP..TSSA..AT..........SLS......R.N....PFL....N..SS.RPRLRFNPYQI.P..VS.I.PQST.....NLLTTGL............................................
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A0A8C8C1I3_ONCTS/521-626 .....................................GASGMEN.G.S.L.S.-..A..Q........G....T.....G..G..AP.......NPFP..F.H.LS.QH..............ML...............A.S....Q.GIS.M...PTFG..GLFPYPYTYMA....AAAAA....A.SA....MP..ASTT..AS..........SLS......R.N....PFL....T..SS.RPRLRFNPYQL.P..VS.M.AQST.....SLFTTGL............................................
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A0AAD1R1N7_PELCU/507-613 .....................................GASGLEN.G.A.L.S.A..V..Q........G....A.....A..G..AA.......TPFP..F.H.LS.QH..............ML...............A.S....Q.GIP.M...PAFG..GLFPYPYTYMA....AAAAA....A.SA....MP..ATSA..AT..........TMP......R.N....PFL....T..ST.RPRLRFSPYQL.P..VT.I.PPST.....NLLTTGL............................................
A0A7L1Z9Q2_LEILU/513-623 ...................................gg--GSLEN.G.A.L.S.S..A..P........G....A.....A..G..TA.......TPFP..F.H.LS.QH..............ML...............A.S....Q.GIP.M...PTFG..GLFPYPYTYMA....AAAAA....A.SA....MP..ATSA..AAaa......agPLS......R.N....PFL....G..SS.RPRLRFSPYQL.P..VT.I.PPST.....NLLTTGL............................................
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A0A7K9NDC0_9CORV/513-621 ...................................gg--GSLEN.G.A.L.S.S..A..P........G....A.....A..G..TA.......TPFP..F.H.LS.QH..............ML...............A.S....Q.GIP.M...PTFG..GLFPYPYTYMA....AAAAA....A.SA....MP..ATSA..AAa........gPLS......R.N....PFL....G..SS.RPRLRFSPYQL.P..VT.I.PPST.....NLLTTGL............................................
A0A7L0AVH8_9AVES/290-398 ...................................gg--GSLEN.G.A.L.S.S..A..P........G....A.....A..G..TA.......TPFP..F.H.LS.QH..............ML...............A.S....Q.VSP.R...AHPA..SPSPSPPRAST....WLSPV....S.LS....LRxtSAAA..AG..........PLS......R.N....PFL....G..SS.RPRLRFSPYQL.P..VT.I.PPST.....NLLTTGL............................................
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A0A8C7FR36_ONCKI/488-596 ....................................g-VCSMGT.A.G.IpV.S..S..V........Q....R.....V..S..GT.......SGLP..L.N.FQ.QH..............AM...............A.S....Q.GLT.V...SPFG..AIFPYPYSHLA....TTAAL....-.--....--..STTA..ST..........PVH......R.R....SVTpvhrR..PV.RPPTRFRPYLI.SnrVG.L.PDNC.....-------stpptsi.....................................
A0A671MWK3_9TELE/510-617 .....................................GAGGLEN.G.S.L.L.-..V..Q........G....T.....G..S..TP.......SPFP..F.H.LS.QH..............ML...............A.S....Q.GIP.M...PTFG..GLFPYPYTYMA....AAAAA....A.SA....LP.aNSNT..AS..........SLS......R.N....PFL....S..SStRSRLRFNPYQL.P..VS.I.PQST.....NLLTTG-f...........................................
A0A8C3XUF3_CHESE/533-636 .....................................GVSGLDS.T.V.M.A.T..A..A.......aQ....G.....L..S..GAs.....aAALP..F.H.LQ.QH..............VL...............A.S....Q.GLA.M...SPFG..SLFPYPYTYMA....AAAAA....-.--....--..-SSA..AS..........SVH......R.H....PFL....S..AV.RPRLRYSPYSI.P..VP.L.PDSS.....SLLPTAL............................................
A0A7L4H5E3_PODST/546-650 .....................................GVSGLDN.T.V.M.A.T..A..A.......aQ....G.....L..S..GAs.....aAALP..F.H.LQ.QH..............VL...............A.S....Q.GLA.M...SPFG..SLFPYPYTYMA....AAAAA....-.--....--..SSAA..SS..........SVH......R.H....PFL....S..AV.RPRLRYSPYPL.P..VP.L.PDGS.....SLLTTAL............................................
A0A7K7DZJ7_9SYLV/546-585 .....................................GVSGLDN.T.V.M.A.T..A..A.......aQ....G.....L..S..GAs.....aAALP..F.H.LQ.QH..............VL...............A.S....Q.V--.-...----..-----------....-----....-.--....--..----..--..........---......-.-....---....-..--.-----------.-..--.-.----.....-------l...........................................
A0A6P8NNM3_GEOSA/404-511 ...........................ghllasmtgg-------.G.S.L.E.-..-..T........G....A.....T..G..TA.......AAFP..F.H.LS.QH..............ML...............A.S....Q.GIP.M...PTFG..GLFPYPYTYMA....AAAAA....A.SA....MP..ATSA..AS..........SLA......R.N....PFL....S..SA.RPRLRFSPYQI.P..VA.I.PPSS.....NLLATGL............................................
A0A7K5FMX5_PROAR/513-621 ...................................gg--GSLEN.G.A.L.S.S..A..P........G....T.....A..G..TA.......TPFP..F.H.LS.QH..............ML...............A.S....Q.GIP.M...PTFG..GLFPYPYTYMA....AAAAA....A.SA....MP..ATSA..AAa........gPLS......R.N....PFL....G..SS.RPRLRFSPYQL.P..VT.I.PPST.....NLLTTGL............................................
A0A8C3NVV6_9PASS/546-650 .....................................GVSGLDN.T.V.M.A.T..A..A.......aQ....G.....L..S..GAs.....aAALP..F.H.LQ.QH..............VL...............A.S....Q.GLA.M...SPFG..SLFPYPYTYMA....AAAAA....-.--....--..SSAA..SS..........SVH......R.H....PFL....S..AV.RPRLRYSPYPL.P..VP.L.SDGS.....SLLTTAL............................................
A0A2I3M0K5_PAPAN/532-640 .....................................GVSGLDS.T.A.M.A.S..A..A........A....Aq...gL..SgaSA.......ATLP..F.H.LQ.QH..............VL...............A.S....Q.GLA.M...SPFG..SLFPYPYTYMA....AAAAA....S.SA....--..--AA..SS..........SVH......R.H....PFL....NlnTM.RPRLRYSPYSI.P..VP.V.PDGS.....SLLTTAL............................................
A0AA97N0A5_9PASS/513-621 ...................................gg--GSLEN.G.A.L.S.S..A..P........G....A.....A..G..TA.......TPFP..F.H.LS.QH..............ML...............A.S....Q.GIP.M...PTFG..GLFPYPYTYMA....AAAAA....A.SA....MP..ATSAgaAG..........PLT......R.N....PFL....G..SS.RPRLRFSPYQL.P..VT.I.PPST.....NLLTTGL............................................
A0A7K8E8W1_LEURO/543-589 .....................................GVSGLDN.T.V.M.A.T..A..A.......aQ....G.....L..S..GAs.....aAALP..F.H.LQ.QH..............VL...............A.S....Q.VLP.S...P---..-----------....-----....-.--....--..----..--..........---......-.-....---....-..--.-----------.-..--.-.----.....-------raap........................................
A0A671SC73_9TELE/520-618 .....................................GVSSMDT.S.S.M.P.S..P..S........Q....S.....L..T..GA.......-PLP..F.H.LQ.QH..............VL...............A.S....Q.GLA.M...SPFG..GLFPYPYTYMA....AAAAA....-.--....--..SSAA..SS..........SVH......R.H....PFL....N..AV.RPRLRYSPYSL.P..-S.V.PDST.....-LLTTAV............................................
A0A7L3C8J1_PELUR/546-650 .....................................GVSGLDN.T.V.M.A.T..A..A.......aQ....G.....L..S..GAs.....aAALP..F.H.LQ.QH..............VL...............A.S....Q.GLA.M...SPFG..SLFPYPYTYMA....AAAAA....-.--....--..SSAA..SS..........SVH......R.H....PFL....N..AV.RPRLRYSPYPL.P..VP.L.PDGS.....SLLTTAL............................................
A0A8C4TVB1_FALTI/542-646 .....................................GVSGLDN.T.V.M.A.T..A..A.......aQ....G.....L..S..GAs.....aAALP..F.H.LQ.QH..............VL...............A.S....Q.GLA.M...SPFG..SLFPYPYTYMA....AAAAA....-.--....--..SSAA..SS..........SVH......R.H....PFL....S..AV.RPRLRYSPYPL.P..VP.L.PDGS.....SLLTTAL............................................
A0A8C5YY57_MARMA/541-649 .....................................GVSGLDS.S.A.M.A.S..A..A........A....Aq...gL..SgaSA.......ATLP..F.H.LQ.QH..............VL...............A.S....Q.GLA.M...SPFG..SLFPYPYTYMA....AAAAA....S.SA....--..--AA..SS..........SVH......R.H....PFLs..lN..SM.RPRLRYSPYSI.P..VP.V.PDSS.....SLLATAL............................................
A0A672UTU7_STRHB/534-638 .....................................GVSGLDN.T.V.M.A.T..A..A.......aQ....G.....L..S..GAs.....aAALP..F.H.LQ.QH..............VL...............A.S....Q.GLA.M...SPFG..SLFPYPYTYMA....AAAAA....-.--....--..SSAA..SS..........SVH......R.H....PFL....S..AV.RPRLRYSPYPL.P..VP.L.PDGS.....SLLTTAL............................................
A0A4W3GUX7_CALMI/404-440 .....................................GIGGLDA.T.G.I.S.S..P..Q........G...lS.....A..A..SA.......ATLP..F.H.LQ.QH..............ML...............A.S....Q.---.-...----..-----------....-----....-.--....--..----..--..........---......-.-....---....-..--.-----------.-..--.-.----.....-------v...........................................
A0A8C5LMV2_9ANUR/509-615 .....................................GAGGLDN.G.A.L.A.S..I..Q........G....A.....A..G..AA.......TPFP..F.H.LS.QH..............ML...............A.S....Q.GIP.M...PAFG..GLFPYPYTYMA....AAAAA....A.SA....MP..ATSA..AT..........TMP......R.N....PFL....S..TS.RPRLRFSPYQL.P..VS.I.PPST.....NLLTTGL............................................
A0A7L3EFU1_9PASS/513-622 ....................................g-GSSLEN.G.A.L.S.S..A..P........G....A.....A..G..TA.......TPFP..F.H.LS.QH..............ML...............A.S...qQ.GIP.M...PTFG..GLFPYPYTYMA....AAAAA....A.SA....MP..ATSA..AAa........gPLS......R.N....PFL....G..SS.RPRLRFSPYQL.P..VT.I.PPST.....NLLTTGL............................................
A0A8U0PRF6_SALNM/518-623 .....................................GASGMEN.G.S.L.S.-..A..Q........G....T.....G..G..AP.......NPFP..F.H.LS.QH..............ML...............A.S....Q.GIP.M...PTFG..GLFPYPYTYMA....AAAAA....A.SA....MP..ASTT..AS..........SLS......R.N....PFL....T..SS.RPRLRFNPYQI.P..VS.M.AQST.....SLFTTGL............................................
A0A674EB48_SALTR/518-623 .....................................GASGMEN.G.S.L.S.-..A..Q........G....T.....G..G..AP.......NPFP..F.H.LS.QH..............ML...............A.S....Q.GIP.M...PTFG..GLFPYPYTYMA....AAAAA....A.SA....MP..ASTT..AS..........SLS......R.N....PFL....T..SS.RPRLRFNPYQI.P..VS.M.AQST.....SLFTTGL............................................
A0A226MNG5_CALSU/546-650 ....................................g-GSGLDS.T.V.M.A.T..A.aA........Q....G.....L..S..GAs.....tAALP..F.H.LQ.QH..............VL...............A.S....Q.GLA.M...SPFG..SLFPYPYTYMA....AAAAA....-.--....--..SSAA..SS..........SVH......R.H....PFL....N..AV.RPRLRYSPYPL.P..VP.L.PDGS.....SLLTTAL............................................
A0A6P8VEV2_GYMAC/484-592 .............................ghllasvs-----GA.S.G.L.E.N..V..Q........G....S.....G..G..TP.......NPFP..F.H.LS.QH..............ML...............A.S....Q.GIP.M...PPFG..GLFPYPYTYMA....AAAAA....A.SA....-S..ATST..SS..........SLS......R.N....PFL....T..AS.RPRLRFNPYQL.P..VS.L.PQSS.....SLLTTSL............................................
A0A8J6KCC6_ELECQ/530-628 ....................................sGVNSLDS.T.V.M.A.S..S..S........Q....G.....L..P..GA.......SSLP..F.H.LQ.QH..............VL...............A.S....Q.GLA.M...SPFG..GLFSYPYTYMA....AAAAA....-.--....--..----..SS..........AVH......R.H....PFL....N..AV.RPRLRYNPYSF.P..VP.M.PETG.....NLLTTAL............................................
A0A7K4QK49_9TYRA/546-650 .....................................GVSGLDN.T.V.M.A.T..A..A.......aQ....G.....L..S..GAs.....aAALP..F.H.LQ.QH..............VL...............A.S....Q.GLA.M...SPFG..SLFPYPYTYMA....AAAAA....-.--....--..SSAA..SS..........SVH......R.H....PFL....S..AV.RPRLRYSPYPL.P..VP.L.SDGS.....SLLTTAL............................................
A0A3Q7NV05_CALUR/525-642 ................................ggpga-ATGLDA.G.G.L.G.P..A..A........S....A.....A..S..TA.......APFP..F.H.LS.QH..............ML...............A.S....Q.GIP.M...PTFG..GLFPYPYTYMA....AAAAA....A.SA....LP..ATSA..AAaaa...aaagSLS......R.S....HFL....G..SA.RPRLRFSPYQI.P..VT.L.PPGA.....SLLTTGL............................................
A0A7K8QRI9_9PASS/546-650 .....................................GVSGLDN.T.V.M.A.T..A..A.......aQ....G.....L..S..GAs.....aAALP..F.H.LQ.QH..............VL...............A.S....Q.GLA.M...SPFG..SLFPYPYTYMA....AAAAA....-.--....--..SSAA..SS..........SVH......R.H....PFL....S..AV.RPRLRYSPYPL.P..VP.L.SDGS.....SLLTTGL............................................
A0A6F9A5Q2_9TELE/539-639 .....................................GVSTMDT.A.S.M.A.S..P..S........Q....S.....L..T..GA.......HGLP..F.H.LQ.QH..............VL...............A.S....Q.GLA.M...SPFG..GLFPYPYTYMA....AAAAA....-.--....--..SSAA..AS..........SVH......R.H....PFL....N..AV.RPRLRYSPYSI.P..MS.V.PDST.....-LLTTAI............................................
A0A6P7J9U6_9TELE/533-633 .....................................GVSTMDT.A.S.M.A.S..P..P........Q....G.....L..A..GT.......PGLP..F.H.LQ.QH..............VL...............A.S....Q.GIA.M...SPFG..SLFPYPYTYMA....AAAAA....-.--....--..SSAA..SS..........SVH......R.H....PFL....N..AV.RPRLRYSPYSL.P..LT.V.PDST.....-LLTTAM............................................
A0A8C1R655_CYPCA/509-613 .....................................GASGLEN.G.S.L.S.-..-..S........Q....S.....T..S..SP.......NPFP..F.H.LS.QH..............ML...............A.S....Q.GIS.M...PPFG..GLLPYPYTYMA....AAAAA....A.SA....LP..AGVA..AS..........TLS......R.N....PFL....S..SA.RPRLRFSPYQI.P..VS.V.PQSS.....GLLTTD-v...........................................
A0A0D9S4A5_CHLSB/532-640 .....................................GVSGLDS.T.A.M.A.S..A..A........A....Aq...gL..SgaSA.......ATLP..F.H.LQ.QH..............VL...............A.S....Q.GLA.M...SPFG..SLFPYPYTYMA....AAAAA....S.SA....--..--AA..SS..........SVH......R.H....PFL....NlnTM.RPRLRYSPYSI.P..VP.V.PDGS.....SLLTTAL............................................
A0A2U9B3E0_SCOMX/492-532 .....................................GASGLEN.G.S.L.S.-..A..Q........G....T.....G..G..TP.......NPFP..F.H.LS.QH..............ML...............A.S....Q.NIE.-...----..-----------....-----....-.--....--..----..--..........---......-.-....---....-..--.-----------.-..--.-.----.....-------nikv........................................
#=GC seq_cons ......................................souL-s.s.u.h.u.o..A..s........t....u.....h..u..uA.......sshP..F.H.Lp.QH..............hL...............A.S....Q.Gls.M...ssFG..uLFPYPYTYMA....AAAAA....u.sA........uouA..uS..........Slp......R.p....PFL....s..us.RPRLRaSPYpl.P..Vs.l.PsSo.....sLLTTuL............................................
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