#=GF ID TMEM31
#=GF AC PF29362.1
#=GF DE TMEM31
#=GF AU Morveli N;0000-0003-2496-881X
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE ECOD:Q5JXX7_TED01
#=GF GA 27.00 27.00;
#=GF TC 72.70 72.30;
#=GF NC 24.90 18.80;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 90746521 --cpu 8 -E 1000 HMM pfamseq
#=GF TP Domain
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This entry represents the TMEM31 domain found in transmembrane
#=GF CC protein 31 and related proteins. TMEM31 is a multi-pass membrane
#=GF CC protein with two predicted transmembrane helices located in the
#=GF CC C-terminal region. The protein is found predominantly in
#=GF CC vertebrates, particularly mammals, and shows tissue-enriched
#=GF CC expression in testis, according to Bgee database. The N-terminal
#=GF CC region contains predicted disordered regions with low complexity
#=GF CC and polar residue bias.
#=GF SQ 57
#=GS A0A7N9DFI8_MACFA/77-167 AC A0A7N9DFI8.1
#=GS A0A8B7B556_ORYAF/76-164 AC A0A8B7B556.1
#=GS F7EDQ3_CALJA/88-174 AC F7EDQ3.4
#=GS A0A8C5YLH7_MARMA/76-162 AC A0A8C5YLH7.1
#=GS A0A8B8WEZ3_BALMU/77-167 AC A0A8B8WEZ3.1
#=GS A0A6J3A9Z2_VICPA/76-167 AC A0A6J3A9Z2.1
#=GS A0A811Z115_NYCPR/82-173 AC A0A811Z115.1
#=GS A0A8D2I0Q4_UROPR/76-178 AC A0A8D2I0Q4.1
#=GS A0A8C9CID1_PHOSS/76-165 AC A0A8C9CID1.1
#=GS A0A8D2F3Y9_THEGE/76-166 AC A0A8D2F3Y9.1
#=GS A0A8C4KZ99_EQUAS/77-167 AC A0A8C4KZ99.1
#=GS F7B6B6_MACMU/77-167 AC F7B6B6.2
#=GS A0A2K6CPR5_MACNE/90-180 AC A0A2K6CPR5.1
#=GS A0A2K5R0I5_CEBIM/75-164 AC A0A2K5R0I5.1
#=GS A0A671DMM5_RHIFE/76-167 AC A0A671DMM5.1
#=GS A0A8C9HPU7_9PRIM/76-166 AC A0A8C9HPU7.1
#=GS A0A0D9RAL4_CHLSB/76-166 AC A0A0D9RAL4.1
#=GS A0A2K6CPS1_MACNE/77-167 AC A0A2K6CPS1.1
#=GS A0A8C5UNY7_MICMU/76-166 AC A0A8C5UNY7.1
#=GS A0A667IX27_LYNCA/76-166 AC A0A667IX27.1
#=GS A0A2K5J1U7_COLAP/76-166 AC A0A2K5J1U7.1
#=GS A0A2K6P212_RHIRO/76-166 AC A0A2K6P212.1
#=GS A0A7N5JLV6_AILME/77-169 AC A0A7N5JLV6.1
#=GS A0A2K6UBU0_SAIBB/75-163 AC A0A2K6UBU0.1
#=GS A0A8C7BEQ9_NEOVI/81-173 AC A0A8C7BEQ9.1
#=GS A0A8C9MAV1_PANTA/76-166 AC A0A8C9MAV1.1
#=GS A0A2K6GRS6_PROCO/76-166 AC A0A2K6GRS6.1
#=GS A0A384ACZ3_BALAS/76-166 AC A0A384ACZ3.1
#=GS A0A673UAH5_SURSU/76-163 AC A0A673UAH5.1
#=GS A0A8C0QWU6_CANLU/77-168 AC A0A8C0QWU6.1
#=GS A0A2K5W496_MACFA/76-166 AC A0A2K5W496.1
#=GS A0A6J2MLX5_9CHIR/78-166 AC A0A6J2MLX5.1
#=GS A0A2K5YH36_MANLE/76-166 AC A0A2K5YH36.1
#=GS H2QZH6_PANTR/76-166 AC H2QZH6.1
#=GS M3WR23_FELCA/76-166 AC M3WR23.3
#=GS A0A2K5D6T5_AOTNA/75-164 AC A0A2K5D6T5.1
#=GS A0A8C2UI28_CHILA/74-166 AC A0A8C2UI28.1
#=GS A0A452FIE7_CAPHI/68-158 AC A0A452FIE7.1
#=GS A0A8I3VVX7_CALJA/75-161 AC A0A8I3VVX7.1
#=GS A0A452RVQ4_URSAM/83-175 AC A0A452RVQ4.1
#=GS A0A5N3VAB7_MUNRE/52-98 AC A0A5N3VAB7.1
#=GS A0A9W3F766_CAMBA/116-207 AC A0A9W3F766.1
#=GS A0A8C6CJ80_MOSMO/72-162 AC A0A8C6CJ80.1
#=GS A0A8I5TP69_PONAB/75-165 AC A0A8I5TP69.1
#=GS A0A096N4X4_PAPAN/76-166 AC A0A096N4X4.1
#=GS G3SE13_GORGO/77-167 AC G3SE13.2
#=GS A0A8C8Y8G5_PANLE/76-166 AC A0A8C8Y8G5.1
#=GS G1RT63_NOMLE/76-166 AC G1RT63.1
#=GS A0A2R9BWN4_PANPA/76-166 AC A0A2R9BWN4.1
#=GS A0A2K5M3D0_CERAT/76-166 AC A0A2K5M3D0.1
#=GS A0A8I3S7M9_CANLF/67-158 AC A0A8I3S7M9.1
#=GS H2PWD0_PONAB/77-167 AC H2PWD0.3
#=GS TMM31_HUMAN/76-166 AC Q5JXX7.1
#=GS A0A9B0HCL1_ODORO/82-174 AC A0A9B0HCL1.1
#=GS A0A5G2R1D4_PIG/75-168 AC A0A5G2R1D4.1
#=GS A0A8C8YYL3_PROSS/76-166 AC A0A8C8YYL3.1
#=GS A0A3Q2HEC9_HORSE/77-167 AC A0A3Q2HEC9.3
A0A7N9DFI8_MACFA/77-167 .WPTESISNPYRLPALFEL..YPEFF.LVFKEAFHDISHRLKAQMEKIGLPIILHLFALFILYLYKFFLPTILS.LSFFILLELL..LLLFIIVFIL-s.................
A0A8B7B556_ORYAF/76-164 l-SNQYITSPYQLPVVLQF..YPEFF.LIFKEAVHDVSCYLKAYVKEIELPIFLCLSALSTL--QLPALPIVLF.LSSVLLLAIV..FLLLIILFILI..................
F7EDQ3_CALJA/88-174 .WPVEWIVNPYRLPAVFEL..YPEFL.LVFKAAFHDILQCLKAHMETTMLPIILHLCALSTLYNDNSFLLTSLS.PACFILLILL..LLHLL------ls................
A0A8C5YLH7_MARMA/76-162 .WSMQWISSLYQLPDVLPF..YPEFL.LFFEEAFHDMSHCLKAH----PLLIIFHFSALSTFYFHLHFLPVLIF.LSSFIFFLHF..YFCFCFFFFF-f.................
A0A8B8WEZ3_BALMU/77-167 .WPIQXVANPYQLPAVLQF..YPEFL.LVFKEASHDMSHYLKAHVKEIGLPIILHLTALSTLHFHLPFLPTLLF.LSFFLLSVLL..LLLLIILFILV..................
A0A6J3A9Z2_VICPA/76-167 .WPFQWVASPYQLPAVLQF..YPEFL.LVFKEAFHDMSHCLRAYAKEIGLPTIL-LSALSTLHFYLPFLPPLLF.LSFFLPSG-L..LLLLIILFILLlil...............
A0A811Z115_NYCPR/82-173 .WPIQWFASPYQLPAIFQF..YPEFL.LVVKEDFHNMFHCLKAHIKDIGLPIIIHFSVVSTLHSHLPFLPILLF.LYFFILFILL.fLILLIILFILI..................
A0A8D2I0Q4_UROPR/76-178 .WSIQWISSLYQLPDV-QF..YPEFL.LFFKEAFHDMSHCLKAH----PLLIIFHLSALSTFYFHLHFLPVLIF.LSSFIFFLHF..YFCFCFFFFF-ffffffffffffffflip
A0A8C9CID1_PHOSS/76-165 .WPVQ-VANPYQLPAVLQF..YPEFL.LVFKEASHDISHCLKAHVKEIGLPIILHLSALSTLPFHLPFLPTLLF.LSFFLLSLLL..LLLLIILFIL-a.................
A0A8D2F3Y9_THEGE/76-166 .WPTESISNPYRLPALFEL..YPEFF.LVFKEAFHDISHRLKAQMEKIGLPIILHLFALFILYLYKFFLPTILS.LSFFILLELL..LLLFIIVFIL-s.................
A0A8C4KZ99_EQUAS/77-167 .WPLQCVASPYRLPPLLQF..YPEFF.LVFKEAFQDLSRCLKAHIKEIGLPIILHLSALSTFHFHLPVLPILLF.LYFFILSVLL..LLLLIILFILV..................
F7B6B6_MACMU/77-167 .WPTESISNPYRLPALFEL..YPEFF.LVFKEAFHDISHRLKAQMEKIGLPIILHLFALFILYLYKFFLPTILS.LSFFILLELL..LLLFIIVFIL-s.................
A0A2K6CPR5_MACNE/90-180 .WPTESISNPYRLPALFEL..YPEFF.LVFKEAFHDISHRLKAQMEKIGLPIILHLFALFILYLYKFFLPTILS.LSFFILLELL..LLLFIIVFIL-s.................
A0A2K5R0I5_CEBIM/75-164 .WPVEWIFNPYRLPAVFEL..YPEFL.LVFKAAFHDISQCLKAHMEKIRLPIMLHLCALSTLYYYNSFLLTTLS.LAFFILL-IL..LLLLIIVFILI..................
A0A671DMM5_RHIFE/76-167 r-PSQWIASPYQLPAVLQF..YPEFL.LPFKEAFPDLSPCLKAHVKKSRLPTILHVSAFSTPH-HLPFLPTLLF.LPFFLLFVLLflILLLLILFILI..................
A0A8C9HPU7_9PRIM/76-166 .WPTESISNPYRLPALFEL..YPEFF.LVFKEAFHDISHRLKTQMEKIGLPIILHLFALSILYFYNFFLPTILP.LSFFILLELL..LLLFIIVFIL-s.................
A0A0D9RAL4_CHLSB/76-166 .WPTESISNPYRLPALFEL..YPEFF.LVFKEAFHDISHRLKAQMEKIGLPIILHLFALSILYLYKFFFPTILS.LSFFILLELL..LLLFIIVFIL-s.................
A0A2K6CPS1_MACNE/77-167 .WPTESISNPYRLPALFEL..YPEFF.LVFKEAFHDISHRLKAQMEKIGLPIILHLFALFILYLYKFFLPTILS.LSFFILLELL..LLLFIIVFIL-s.................
A0A8C5UNY7_MICMU/76-166 .WPMQWVSSPYQLPDVLQF..YPEFI.LVFKEAFHDTSHCLKAQVKEIGLPILLHLSALFTFFFYLPVLPILLF.LYFFTLFVLL..LLLLIILFILI..................
A0A667IX27_LYNCA/76-166 .WSIQWFASPYQLPAILQF..YPEFL.LVFKEAFHDMSHCLKALVKEIGLPIILYFSALSTLHFHLPFLPTLLF.LSFIPLSLLL..LFLFIILFIII..................
A0A2K5J1U7_COLAP/76-166 .WPTESISNPYRLPALFEL..YPEFF.LVFKEAFHDISHRLKAQMEKIGLPIILHLFALSILYFCNFFLPTIPP.LSFFILLELL..LLLFIIVFIL-s.................
A0A2K6P212_RHIRO/76-166 .WPTESISNPYRLPALFEL..YPEFF.LVFKEAFHDISYRLKAQMEKIGLPIILHLFALSILYFYNFFLPTILP.LSFFILLELL..ILLFIIVFIL-s.................
A0A7N5JLV6_AILME/77-169 .WPIQWFASPYQLPAILQF..YPEFI.LVFKEALHYMSHCLKAHVKEIGLPIILHLSALSTLHFHLPFLPTLLF.LSFFILFVLLflLLLLIILFILF..................
A0A2K6UBU0_SAIBB/75-163 .WPVEWIFNPYRLPAVFEL..YPEFL.LVFKAAFHDISQCLKAHMEKIRLPIIFHLCALSTLCYYNSFLFTTLS.LACFILI--L..LLLFIIVFILI..................
A0A8C7BEQ9_NEOVI/81-173 l-PIQWFTSPYQQPAILQLfsYPEFL.LVFKEAFQDMSHCLKAHIKEIGIPIILHLSALSTLHFHLPFLPVLLS.FFLLFVLLFL..LLLLIILFIL-c.................
A0A8C9MAV1_PANTA/76-166 .WSIQLFASPYQLPAILQF..YPEFL.LVFKEAFHNMSHCLKALVKEIGLPIILYFSALSTLHFHLPFLPTLLL.LSFIPFSLLL..LFLFIILFIII..................
A0A2K6GRS6_PROCO/76-166 .WPMQWVSSPYQLPDVLQF..YPELL.LVFKEAFHDMAHCLKAHIEEIGLPILLQLSALSNFYFYLPVLPILLF.LYFFTLFVLL..LLLLIILFILI..................
A0A384ACZ3_BALAS/76-166 .WPIQXVANPYQLPAVLQF..YPEFL.LVFKEASHDMSHYLKAHVKEIGLPIILHLTALSTLHFHLPFLPTLLF.LSFFLLSVLL..LLLLIILFILV..................
A0A673UAH5_SURSU/76-163 .WPIQWFASPYQLP-ILQF..YPEFL.MVFKEAFHNTSHCLKALVKEIGLPIILYFSALSTLHFHLPFLPTLLF.LSFIPFS--L..LLLLIILFILI..................
A0A8C0QWU6_CANLU/77-168 .WPIQWFASPYQLPAIFQF..YPEFL.LVVKEDFHNMFHCLKAHIKEIGLPIIIHFSVLSTLHSYLPFLPILLF.LSFFILFILL.fLILLIILFILI..................
A0A2K5W496_MACFA/76-166 .WPTESISNPYRLPALFEL..YPEFF.LVFKEAFHDISHRLKAQMEKIGLPIILHLFALFILYLYKFFLPTILS.LSFFILLELL..LLLFIIVFIL-s.................
A0A6J2MLX5_9CHIR/78-166 .WPIQXVVNTYQLP-VLQF..HPEFLsFFFKEAFHDISNCLKSHVKEI----IFHLFALSTLHFHLLFLPTVLF.LSFFFSFVLLllTLLLIILFILI..................
A0A2K5YH36_MANLE/76-166 .WPTESISNPYRLPALFEL..YPEFF.LVFKEVFHDISHRLKAQMEKIGLPIILHLFALFILYLYKFFLPTILS.LSFFILLELL..LLLFIIVFIL-s.................
H2QZH6_PANTR/76-166 .WPTEWIFNPYRLPALFEL..YPEFL.LVFKEAFHDISHCLKAQMEKIGLPIILHLFALSTLYFYKFFLPTILS.LSFFILLVLL..LLLFIIVFILI..................
M3WR23_FELCA/76-166 .WSIQWFASPYQLPAILQF..YPEFL.LVFKEAFHDMSHCLKALVKEIGLPIILYFSALSTLHFHLPFLPTLLF.LSFIPLSLLL..LFLFIIRFIII..................
A0A2K5D6T5_AOTNA/75-164 .WHVERILNPYRLPAVFEL..YPEFL.LVFQAAFHDISQRLKAHMKMMILRIILHLCAVSALYCYNSFPLTTLA.LALFILV-IL..LLLFIIAFILI..................
A0A8C2UI28_CHILA/74-166 .WPIEWISSPYQLPAVFQF..YPGAF.AALKEAFQDLSQYLRAQIMKIGLPFILQFSALSALHFCLPFLPVLLF.LSSFILVEFLllPLILIILFILV..................
A0A452FIE7_CAPHI/68-158 r-PLSWITSLHQLPAILQL..YRDFL.LVFKEAFLDMFHYLKDCVKNIKLPVMLHPSALFTLHFQLLFLPVPFF.LPFFLLFEFL..LLLLIVLFILI..................
A0A8I3VVX7_CALJA/75-161 .WPVEWIVNPYRLPAVFEL..YPEFL.LVFKAAFHDILQCLKAHMETTMLPIILHLCALSTLYNDNSFLLTSLS.PACFILLILL..LLHLL------ls................
A0A452RVQ4_URSAM/83-175 .WPIQWFASPYQLPAILQF..YPEFI.LVFKEALHCMSHCLKAHVKEIGLPIILHLSALSTLHLHLPFLPILLF.LSFFILFVLLflLLLLIILFILF..................
A0A5N3VAB7_MUNRE/52-98 .WPLPWITSLHQLPAILQL..YPEFL.LVFKEAFLDMSHYLKDYVKKIRL------------------------.----------..-----------d.................
A0A9W3F766_CAMBA/116-207 .WPIQWVASPYQLPAVLQF..YPEFL.LVFKEAFHDMSHCLRAYAKEIGLPTIL-LSALSTLHFYLPFLPPLLF.LSFFLPSG-L..LLLLIILFILLlil...............
A0A8C6CJ80_MOSMO/72-162 .WPLQWITSLHQLPAILQL..YPEFL.LVFKEAFIDMSHYPKDYVKKIRLPIMLHPSALFTLHFHLLFLPILLF.LPFFFLFELL..LLLLIILFILI..................
A0A8I5TP69_PONAB/75-165 .WPTEWIFNPYRLPALFEL..YPEFL.LVFKEAFHDISHCLKAQMEKIGLPIILHLFALSTLYFYKFFLPTILS.LSFFILLVLL..LLLFIIVFILI..................
A0A096N4X4_PAPAN/76-166 .WPTESISNPYRLPALFEL..YPEFF.LVFKEAFHDISHRLKAQMEKIGLPIILHLFALFILYLYKFFLPTILS.LSFFILLELL..LLLFIIVFIL-s.................
G3SE13_GORGO/77-167 .WPTEWIFNPYRLPALFEL..YPEFL.LVFKEAFHDISHCLKAQMEKIGLPIILHLFALSTLYFYKFFLPTILS.LPFFILLVLL..LLLFIIVFILI..................
A0A8C8Y8G5_PANLE/76-166 .WSIQLFASPYQLPAILQF..YPEFL.LVFKEAFHNMSHCLKALVKEIGLPIILYFSALSTLHFHLPFLPTLLL.LSFIPFSLLL..LFLFIILFIII..................
G1RT63_NOMLE/76-166 .WPTEWIFNPYRLPALFEL..YPEFL.LVFKEAFHDISHCLKAQMEKIGLPIVLHLFTLSTLYFYKIFLPTVLS.LSFFILPILL..LLLFIIVFILI..................
A0A2R9BWN4_PANPA/76-166 .WPTEWIFNPYRLPALFEL..YPEFL.LVFKEAFHDISHCLKAQMEKIGLPIILHLFALSTLYFYKFFLPTILS.LSFFILLVLL..LLLFIIVFILI..................
A0A2K5M3D0_CERAT/76-166 .WPTESISNPYRLPALFEL..YPEFF.LVFKEAFHDISHRLKAQMEKIGLPIILHLFALFILYLYKFFLPTILS.LSFFILLELL..LLLFIIVFIL-s.................
A0A8I3S7M9_CANLF/67-158 .WPIQWFASPYQLPAIFQF..YPEFL.LVVKEDFHNMFHCLKAHIKEIGLPIIIHFSVLSTLHSYLPFLPILLF.LSFFILFILL.fLILLIILFILI..................
H2PWD0_PONAB/77-167 .WPTEWIFNPYRLPALFEL..YPEFL.LVFKEAFHDISHCLKAQMEKIGLPIILHLFALSTLYFYKFFLPTILS.LSFFILLVLL..LLLFIIVFILI..................
TMM31_HUMAN/76-166 .WPTEWIFNPYRLPALFEL..YPEFL.LVFKEAFHDISHCLKAQMEKIGLPIILHLFALSTLYFYKFFLPTILS.LSFFILLVLL..LLLFIIVFILI..................
A0A9B0HCL1_ODORO/82-174 .WPIQWFASPYQLPAILQF..YPEFL.LVFKEAFHDMSHCLKAHVKEIGLPIILHLSELSTLHFYLTFLPTLLF.LSFFVLFILLflLLLLIILFILF..................
A0A5G2R1D4_PIG/75-168 p-PIQWVASPYQLPALLQL..YPEFL.LVFKEAFPAMSHYLKAHVKEICLPMVLHLSALSTLHLHLPSLPMLPSsLSFFLFL-SF..FLSFFLSFFL-sfff..............
A0A8C8YYL3_PROSS/76-166 .WPMQWISNPYQLPDVLQF..YPEFL.LVFKEAFHDTSHCLKVHIKEIGLPILLHLSALSSFYFYLPVLPLLLF.LYFFTLFVIL..FLLLIILFILI..................
A0A3Q2HEC9_HORSE/77-167 .WPLQCVASPYRLPPLLQF..YPEFF.LVFKEAFQDLSRCLKAHIKEIGLPIILHLSALSTFHFHLPVLPILLF.LYFFIISVLL..LLLLIILFILV..................
#=GC seq_cons .WPhpalusPYpLPAlhph..YPEFL.LVFKEAFHDhSHCLKAphccIGLPIILHLsALSTLaaah.FLPTlL..LSFFILhhLL..LLLhIIlFILh..................
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