GenomeNet

Database: Pfam
Entry: TRH
LinkDB: TRH
Original site: TRH 
#=GF ID   TRH
#=GF AC   PF05438.15
#=GF DE   Thyrotropin-releasing hormone (TRH)
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_14384 (release 8.0)
#=GF GA   27.80 27.80;
#=GF TC   31.70 28.30;
#=GF NC   25.40 27.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Thyrotropin-releasing_hormone
#=GF RN   [1]
#=GF RM   10526628
#=GF RT   Thyrotropin-releasing hormone (TRH), a signal peptide of the
#=GF RT   central nervous system. 
#=GF RA   Heuer H, Schafer MK, Bauer K; 
#=GF RL   Acta Med Austriaca 1999;26:119-122.
#=GF RN   [2]
#=GF RM   12467901
#=GF RT   Neuroprotective effect and brain receptor binding of taltirelin,
#=GF RT   a novel thyrotropin-releasing hormone (TRH) analogue, in
#=GF RT   transient forebrain ischemia of C57BL/6J mice. 
#=GF RA   Urayama A, Yamada S, Kimura R, Zhang J, Watanabe Y; 
#=GF RL   Life Sci 2002;72:601-607.
#=GF DR   INTERPRO; IPR008857;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several thyrotropin-releasing hormone
#=GF CC   (TRH) proteins. Thyrotropin-Releasing Hormone (TRH;
#=GF CC   pyroGlu-His-Pro-NH2), originally isolated as a hypothalamic
#=GF CC   neuropeptide hormone, most likely acts also as a neuromodulator
#=GF CC   and/or neurotransmitter in the central nervous system (CNS).
#=GF CC   This interpretation is supported by the identification of a
#=GF CC   peptidase localised on the surface of neuronal cells which has
#=GF CC   been termed TRH-degrading ectoenzyme (TRH-DE) since it
#=GF CC   selectively inactivates TRH [1]. TRH has been used clinically
#=GF CC   for the treatment of spinocerebellar degeneration and
#=GF CC   disturbance of consciousness in humans [2].
#=GF SQ   319
#=GS A0A2G9RV07_LITCT/6-102    AC A0A2G9RV07.1
#=GS A0A6G1A3S0_CROCR/1-131    AC A0A6G1A3S0.1
#=GS A0A672V532_STRHB/7-227    AC A0A672V532.1
#=GS H2P9C6_PONAB/6-206        AC H2P9C6.1
#=GS A0A2U3VLJ9_ODORO/6-203    AC A0A2U3VLJ9.1
#=GS A0A3Q1HVY8_ANATE/6-233    AC A0A3Q1HVY8.1
#=GS A0A3Q2WFM2_HAPBU/6-235    AC A0A3Q2WFM2.1
#=GS A0A3Q1FSH4_9TELE/6-235    AC A0A3Q1FSH4.1
#=GS A0A485MGW7_LYNPA/6-202    AC A0A485MGW7.1
#=GS A0A673XAM0_SALTR/6-224    AC A0A673XAM0.1
#=GS A0A093ITK7_DRYPU/7-223    AC A0A093ITK7.1
#=GS M3Z0M6_MUSPF/10-211       AC M3Z0M6.1
#=GS I3NCI2_ICTTR/6-204        AC I3NCI2.1
#=GS A0A091DAC2_FUKDA/114-180  AC A0A091DAC2.1
#=GS A0A226MKF2_CALSU/22-239   AC A0A226MKF2.1
#=GS A0A091QB96_MERNU/7-227    AC A0A091QB96.1
#=GS A0A5A9NVM0_9TELE/6-202    AC A0A5A9NVM0.1
#=GS A0A6A5EM38_PERFL/6-235    AC A0A6A5EM38.1
#=GS A0A3N0XN60_ANAGA/5-199    AC A0A3N0XN60.1
#=GS W5MZE0_LEPOC/6-119        AC W5MZE0.1
#=GS A0A2Y9HGD8_NEOSC/6-207    AC A0A2Y9HGD8.1
#=GS A0A673MB97_9TELE/6-111    AC A0A673MB97.1
#=GS A0A2K6BPH5_MACNE/6-207    AC A0A2K6BPH5.1
#=GS U3IIA1_ANAPP/7-227        AC U3IIA1.1
#=GS A0A6J3GK28_SAPAP/6-206    AC A0A6J3GK28.1
#=GS A0A3Q7U489_VULVU/6-204    AC A0A3Q7U489.1
#=GS A0A498LVT4_LABRO/38-227   AC A0A498LVT4.1
#=GS TRH_DANRE/3-69            AC Q5EDF9.1
#=GS G3R1J0_GORGO/4-197        AC G3R1J0.2
#=GS A0A6P7YD39_9AMPH/6-219    AC A0A6P7YD39.1
#=GS A0A6P7N0D6_BETSP/6-218    AC A0A6P7N0D6.1
#=GS A0A3P8THN4_AMPPE/6-235    AC A0A3P8THN4.1
#=GS A0A060XDV6_ONCMY/6-224    AC A0A060XDV6.1
#=GS R7V6P3_CAPTE/26-192       AC R7V6P3.1
#=GS A0A7N4NMF2_SARHA/7-176    AC A0A7N4NMF2.1
#=GS A0A6J2Q1W5_COTGO/6-235    AC A0A6J2Q1W5.1
#=GS A0A2Y9D5X8_TRIMA/5-202    AC A0A2Y9D5X8.1
#=GS A0A384AZD9_BALAS/6-118    AC A0A384AZD9.1
#=GS A0A671PKN9_9TELE/85-171   AC A0A671PKN9.1
#=GS A0A1A6HWM7_NEOLE/131-216  AC A0A1A6HWM7.1
#=GS A0A672SC05_SINGR/6-93     AC A0A672SC05.1
#=GS A0A093HSA7_STRCA/7-227    AC A0A093HSA7.1
#=GS A0A2P4TH66_BAMTH/8-227    AC A0A2P4TH66.1
#=GS L5M7T1_MYODS/6-207        AC L5M7T1.1
#=GS Q4RJV2_TETNG/1-226        AC Q4RJV2.1
#=GS A0A444V2Q0_ACIRT/15-129   AC A0A444V2Q0.1
#=GS A0A1L8GHM5_XENLA/96-135   AC A0A1L8GHM5.1
#=GS A0A093TKE2_PHACA/7-227    AC A0A093TKE2.1
#=GS A0A444UT45_ACIRT/6-120    AC A0A444UT45.1
#=GS D2HGM5_AILME/6-207        AC D2HGM5.1
#=GS A0A1V4JIY5_PATFA/7-225    AC A0A1V4JIY5.1
#=GS A0A6J1UNR0_9SAUR/88-188   AC A0A6J1UNR0.1
#=GS A0A341CBU3_NEOAA/19-227   AC A0A341CBU3.1
#=GS A0A6P3FRV8_OCTDE/5-117    AC A0A6P3FRV8.1
#=GS A0A5J5DDR6_9PERO/6-235    AC A0A5J5DDR6.1
#=GS A0A6P6PYN1_CARAU/5-196    AC A0A6P6PYN1.1
#=GS A0A673KFS2_9TELE/85-171   AC A0A673KFS2.1
#=GS U3KGX4_FICAL/7-224        AC U3KGX4.1
#=GS A0A3Q7Q682_CALUR/6-203    AC A0A3Q7Q682.1
#=GS A0A341CEB2_NEOAA/6-215    AC A0A341CEB2.1
#=GS H0XH21_OTOGA/6-206        AC H0XH21.1
#=GS L5K895_PTEAL/6-209        AC L5K895.1
#=GS A0A341CC30_NEOAA/19-228   AC A0A341CC30.1
#=GS A0A444V2Q0_ACIRT/125-253  AC A0A444V2Q0.1
#=GS F1SPI7_PIG/6-206          AC F1SPI7.1
#=GS A0A096MUB8_PAPAN/6-207    AC A0A096MUB8.1
#=GS A0A6J8D9Q4_MYTCO/9-155    AC A0A6J8D9Q4.1
#=GS K7FNZ1_PELSI/102-205      AC K7FNZ1.1
#=GS A0A2I2YGS0_GORGO/9-199    AC A0A2I2YGS0.1
#=GS W5MZE0_LEPOC/105-245      AC W5MZE0.1
#=GS A0A3Q3XR37_MOLML/6-231    AC A0A3Q3XR37.1
#=GS A0A4W6D6S9_LATCA/6-235    AC A0A4W6D6S9.1
#=GS F1QKW8_DANRE/3-70         AC F1QKW8.1
#=GS H3C5L3_TETNG/6-81         AC H3C5L3.1
#=GS A0A2U9BZW3_SCOMX/109-180  AC A0A2U9BZW3.1
#=GS A0A6J1UNR0_9SAUR/8-101    AC A0A6J1UNR0.1
#=GS A0A1S3ENE1_DIPOR/6-121    AC A0A1S3ENE1.1
#=GS A0A091KUK0_9GRUI/7-227    AC A0A091KUK0.1
#=GS A0A3Q0CLB9_MESAU/126-211  AC A0A3Q0CLB9.1
#=GS A0A3B1IFV0_ASTMX/77-186   AC A0A3B1IFV0.1
#=GS L9JDC1_TUPCH/125-198      AC L9JDC1.1
#=GS TRH_RAT/137-223           AC P01150.1
#=GS A0A1S3ENE1_DIPOR/98-190   AC A0A1S3ENE1.1
#=GS A0A672SC05_SINGR/85-171   AC A0A672SC05.1
#=GS G1ND92_MELGA/7-225        AC G1ND92.1
#=GS A0A3P8Z7L5_ESOLU/6-224    AC A0A3P8Z7L5.1
#=GS A0A091Q0D0_LEPDC/7-227    AC A0A091Q0D0.1
#=GS A0A2I0LUB3_COLLI/6-225    AC A0A2I0LUB3.1
#=GS A0A2Y9MHD5_DELLE/6-202    AC A0A2Y9MHD5.1
#=GS M4AS06_XIPMA/6-234        AC M4AS06.2
#=GS A0A2K6LC50_RHIBE/6-207    AC A0A2K6LC50.1
#=GS A0A094L2W6_ANTCR/7-227    AC A0A094L2W6.1
#=GS A0A384CMJ5_URSMA/6-207    AC A0A384CMJ5.1
#=GS A0A671QV77_9TELE/74-186   AC A0A671QV77.1
#=GS A0A5N3XY02_MUNRE/6-207    AC A0A5N3XY02.1
#=GS A0A2U9BZW3_SCOMX/174-390  AC A0A2U9BZW3.1
#=GS K7E2N6_MONDO/7-156        AC K7E2N6.1
#=GS A0A5N5NMA4_PANHP/46-252   AC A0A5N5NMA4.1
#=GS A0A2I0U400_LIMLA/35-255   AC A0A2I0U400.1
#=GS A0A3P8Z7U9_ESOLU/12-230   AC A0A3P8Z7U9.1
#=GS A0A093NQW3_PYGAD/7-227    AC A0A093NQW3.1
#=GS G1SQS8_RABIT/42-245       AC G1SQS8.3
#=GS A0A1S2ZCD1_ERIEU/128-188  AC A0A1S2ZCD1.1
#=GS A0A484H381_SOUCH/73-269   AC A0A484H381.1
#=GS G3GS26_CRIGR/6-214        AC G3GS26.1
#=GS A0A6I9P6G9_9TELE/6-235    AC A0A6I9P6G9.1
#=GS A0A667YG81_9TELE/63-180   AC A0A667YG81.1
#=GS A0A6J1Y176_ACIJB/34-230   AC A0A6J1Y176.1
#=GS A0A673U5H5_SURSU/6-203    AC A0A673U5H5.1
#=GS K7FNZ1_PELSI/6-106        AC K7FNZ1.1
#=GS A0A6P3J2N3_BISBI/6-181    AC A0A6P3J2N3.1
#=GS H2TW65_TAKRU/6-234        AC H2TW65.2
#=GS A0A3M0JK71_HIRRU/7-223    AC A0A3M0JK71.1
#=GS A0A5E4B3S7_MARMO/6-204    AC A0A5E4B3S7.1
#=GS A0A384AZD9_BALAS/115-179  AC A0A384AZD9.1
#=GS A0A6P7IDD6_9TELE/6-234    AC A0A6P7IDD6.1
#=GS M7C513_CHEMY/5-225        AC M7C513.1
#=GS A0A6P9D7E3_PANGU/88-188   AC A0A6P9D7E3.1
#=GS A0A060YLI9_ONCMY/80-193   AC A0A060YLI9.1
#=GS A0A668W146_OREAU/6-235    AC A0A668W146.1
#=GS A0A093Q948_9PASS/7-227    AC A0A093Q948.1
#=GS A0A669PHD9_PHACC/7-226    AC A0A669PHD9.1
#=GS G3TEL3_LOXAF/5-90         AC G3TEL3.1
#=GS G7N7T8_MACMU/6-207        AC G7N7T8.1
#=GS A0A4W5LH42_9TELE/6-224    AC A0A4W5LH42.1
#=GS A0A3Q4HTY2_NEOBR/6-212    AC A0A3Q4HTY2.1
#=GS A0A7N9DDD8_MACFA/6-203    AC A0A7N9DDD8.1
#=GS A0A3B1JZN7_ASTMX/6-206    AC A0A3B1JZN7.1
#=GS H2QNC9_PANTR/6-205        AC H2QNC9.1
#=GS A0A672ITL9_SALFA/6-231    AC A0A672ITL9.1
#=GS A0A0A0ACE4_CHAVO/7-227    AC A0A0A0ACE4.1
#=GS A0A2R9C4N0_PANPA/6-205    AC A0A2R9C4N0.1
#=GS A0A4W5MW17_9TELE/6-223    AC A0A4W5MW17.1
#=GS A0A402EFZ5_9SAUR/97-318   AC A0A402EFZ5.1
#=GS A0A3Q7X3N9_URSAR/6-207    AC A0A3Q7X3N9.1
#=GS TRH_MOUSE/6-125           AC Q62361.2
#=GS A0A060YLI9_ONCMY/6-82     AC A0A060YLI9.1
#=GS A0A6I9YIB5_9SAUR/8-101    AC A0A6I9YIB5.1
#=GS A0A2I2U1H2_FELCA/45-241   AC A0A2I2U1H2.2
#=GS A0A2K5HPM3_COLAP/6-207    AC A0A2K5HPM3.1
#=GS A0A2G9RV07_LITCT/99-208   AC A0A2G9RV07.1
#=GS G1QZG4_NOMLE/6-207        AC G1QZG4.1
#=GS A0A3Q2E740_CYPVA/6-234    AC A0A3Q2E740.1
#=GS A0A341CCR0_NEOAA/19-215   AC A0A341CCR0.1
#=GS A0A671PKN9_9TELE/6-96     AC A0A671PKN9.1
#=GS A0A5N4D0T8_CAMDR/47-247   AC A0A5N4D0T8.1
#=GS I3KKT6_ORENI/6-235        AC I3KKT6.1
#=GS H3AN56_LATCH/7-227        AC H3AN56.1
#=GS TRH_MOUSE/141-224         AC Q62361.2
#=GS A0A1U7RQM3_ALLSI/6-227    AC A0A1U7RQM3.1
#=GS R0K990_ANAPL/7-227        AC R0K990.1
#=GS A0A6I9K537_CHRAS/5-115    AC A0A6I9K537.1
#=GS A0A4W3KA22_CALMI/11-256   AC A0A4W3KA22.1
#=GS A0A6I9L750_PERMB/25-239   AC A0A6I9L750.1
#=GS A0A452QC57_URSAM/6-207    AC A0A452QC57.1
#=GS A0A6J0UCI8_9SAUR/7-107    AC A0A6J0UCI8.1
#=GS A0A6P3QRU2_PTEVA/6-209    AC A0A6P3QRU2.1
#=GS A0A674DD14_SALTR/46-137   AC A0A674DD14.1
#=GS D6RFM1_HUMAN/6-202        AC D6RFM1.1
#=GS A0A212C900_CEREH/18-219   AC A0A212C900.1
#=GS A0A1L8GHM5_XENLA/4-100    AC A0A1L8GHM5.1
#=GS A0A6J2IQU2_9PASS/7-227    AC A0A6J2IQU2.1
#=GS A0A0Q3URX9_AMAAE/84-304   AC A0A0Q3URX9.1
#=GS A0A151MK38_ALLMI/41-262   AC A0A151MK38.1
#=GS A0A6P5JTB4_PHACI/7-219    AC A0A6P5JTB4.1
#=GS A0A093FXE0_GAVST/7-227    AC A0A093FXE0.1
#=GS A0A3Q3EL52_9LABR/6-235    AC A0A3Q3EL52.1
#=GS A0A2Y9J1E0_ENHLU/14-215   AC A0A2Y9J1E0.1
#=GS A0A671QV77_9TELE/5-112    AC A0A671QV77.1
#=GS A0A6P7YIG4_9AMPH/37-250   AC A0A6P7YIG4.1
#=GS A0A663EUX0_AQUCH/7-227    AC A0A663EUX0.1
#=GS A0A4D9EY34_9SAUR/5-226    AC A0A4D9EY34.1
#=GS A0A091U5R6_PHALP/8-227    AC A0A091U5R6.1
#=GS A0A643C755_BALPH/37-180   AC A0A643C755.1
#=GS A0A093ILQ3_FULGA/7-227    AC A0A093ILQ3.1
#=GS A0A2K5QKB5_CEBIM/6-206    AC A0A2K5QKB5.1
#=GS C3ZWL4_BRAFL/143-309      AC C3ZWL4.1
#=GS TRH_DANRE/68-174          AC Q5EDF9.1
#=GS A0A099YTJ5_TINGU/7-226    AC A0A099YTJ5.1
#=GS A0A6J3DIJ6_AYTFU/7-227    AC A0A6J3DIJ6.1
#=GS A0A498MQI5_LABRO/6-193    AC A0A498MQI5.1
#=GS A0A665T7T8_ECHNA/6-238    AC A0A665T7T8.1
#=GS A0A673XIQ4_SALTR/6-210    AC A0A673XIQ4.1
#=GS A0A5F4CS19_CANLF/46-245   AC A0A5F4CS19.1
#=GS A0A6J2W648_CHACN/6-222    AC A0A6J2W648.1
#=GS S7PNX2_MYOBR/6-207        AC S7PNX2.1
#=GS A0A2U3V0B4_TURTR/6-202    AC A0A2U3V0B4.2
#=GS A0A2K5CWE3_AOTNA/1-175    AC A0A2K5CWE3.1
#=GS A0A556U212_BAGYA/3-209    AC A0A556U212.1
#=GS A0A5F8HDP8_MONDO/14-163   AC A0A5F8HDP8.1
#=GS A0A2F0BAQ4_ESCRO/33-227   AC A0A2F0BAQ4.1
#=GS A0A3Q3AVY8_KRYMA/6-235    AC A0A3Q3AVY8.1
#=GS A0A087QJF5_APTFO/7-227    AC A0A087QJF5.1
#=GS A0A7F8QBF4_LEPWE/1-135    AC A0A7F8QBF4.1
#=GS A0A7N4P3W2_SARHA/117-331  AC A0A7N4P3W2.1
#=GS A0A0P7X5Y1_SCLFO/5-216    AC A0A0P7X5Y1.1
#=GS A0A674DD14_SALTR/94-177   AC A0A674DD14.1
#=GS A0A2I4BUQ6_9TELE/6-233    AC A0A2I4BUQ6.1
#=GS G3TEL3_LOXAF/87-184       AC G3TEL3.1
#=GS W5PU12_SHEEP/45-246       AC W5PU12.1
#=GS W5MZE8_LEPOC/6-228        AC W5MZE8.1
#=GS A0A5F8HDP8_MONDO/156-196  AC A0A5F8HDP8.1
#=GS A0A2Y9MBV8_DELLE/19-215   AC A0A2Y9MBV8.1
#=GS A0A674K4J3_TERCA/5-226    AC A0A674K4J3.1
#=GS A0A3Q1BG00_AMPOC/6-235    AC A0A3Q1BG00.1
#=GS A0A673MB97_9TELE/97-170   AC A0A673MB97.1
#=GS A0A3P9AS00_9CICH/6-233    AC A0A3P9AS00.1
#=GS A0A3B3H917_ORYLA/28-254   AC A0A3B3H917.1
#=GS A0A6P6HRD2_PUMCO/34-230   AC A0A6P6HRD2.1
#=GS A0A091GN18_BUCRH/7-227    AC A0A091GN18.1
#=GS E2RHA2_CANLF/6-205        AC E2RHA2.1
#=GS A0A671VM12_SPAAU/8-238    AC A0A671VM12.1
#=GS A0A4U1EXH5_MONMO/19-215   AC A0A4U1EXH5.1
#=GS A0A6I9HPR0_GEOFO/7-223    AC A0A6I9HPR0.1
#=GS A0A093GNR6_TYTAL/7-225    AC A0A093GNR6.1
#=GS A0A673KFS2_9TELE/6-96     AC A0A673KFS2.1
#=GS A0A2K5LKS6_CERAT/6-207    AC A0A2K5LKS6.1
#=GS A0A6G1Q3W2_9TELE/6-233    AC A0A6G1Q3W2.1
#=GS A0A6I9YIB5_9SAUR/87-188   AC A0A6I9YIB5.1
#=GS A0A091EPA8_CORBR/7-223    AC A0A091EPA8.1
#=GS A0A2Y9SMF2_PHYMC/6-203    AC A0A2Y9SMF2.1
#=GS A0A3Q2X5D7_HAPBU/6-212    AC A0A3Q2X5D7.1
#=GS K7E2N6_MONDO/149-189      AC K7E2N6.1
#=GS A0A672Q2T6_SINGR/5-86     AC A0A672Q2T6.1
#=GS A0A2K6P507_RHIRO/6-207    AC A0A2K6P507.1
#=GS A0A0D9R9X9_CHLSB/2-203    AC A0A0D9R9X9.1
#=GS TRH_RAT/6-134             AC P01150.1
#=GS A0A091GBU8_9AVES/7-227    AC A0A091GBU8.1
#=GS A0A340XQL8_LIPVE/119-306  AC A0A340XQL8.1
#=GS A0A1L8GHM5_XENLA/128-215  AC A0A1L8GHM5.1
#=GS A0A2K5XP22_MANLE/6-207    AC A0A2K5XP22.1
#=GS A0A091W0N2_NIPNI/7-227    AC A0A091W0N2.1
#=GS A0A091DAC2_FUKDA/7-118    AC A0A091DAC2.1
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G1Q2W0_MYOLU/6-202                   ............................................LLLALALTLTLT.GVPGGRAQLEVD.QQ.EAAMaa.ehpALRDL..LRQAGHlLLLREDLQRLQGDQG.N..R..ESG.............S............-........-..........-NGLSKRQHPGK.....R-EE........E.AE..E..----GV.E.D..E..E........E...EGG.........AV.GPHKRQHPGPWENAa.........................aWS.VDV.T.PQKRQHPGRR.S-....-.-....-.--.---..FWL.GY--TFTKRQHP.GR...RLV......----DPK....A.....QRSWEEEE.....................EE.EEE...EGE..LMPEKRQHPGKRA...L-..------...GGPCGLQGD.-.-CGQAS.................
A0A452G1W8_CAPHI/6-207               ............................................FLLAMALTLTLT.SVPGGRAQLDVA.QQ.DVDLse..qqGLEDL..LQQAERlLLLREDLQRLREDQD.D..S..VSE.............S............Qi......fQ..........PDWFSKRQHPGK.....REEE........E.AD..E..----GV.E.G..E..E........E...EGG.........AV.GLRKRQHPGRRDDVa.........................aWA.VDA.G.QQKRQHPGRR.A-....-.-....-.--.---..SWL.GY--AVTKRQHP.GR...RLV......----DPR....P.....QRSWEEAG.....................ED.EDE...GGE..LMSEKRQHPGKRA...L-..------...GSPCGPRGP.-.-CGQAS.................
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T0M605_CAMFR/6-209                   ............................................FLLAMALTLTLT.GVPSGHAQPEMA.QQ.EAAMaa.ehlDLDNL..LRQAERfLFLQEDLQRLREDQD.QgdS..DSE.............S............Qi......fQ..........PDWFSKRQHPGK.....R-EE........E.AE..D..----GV.E.E..E..E........E...EGG.........AA.GPHKRQHPGRREDAa.........................aWL.VDV.T.EQKRQHPGRR.S-....-.-....-.--.---..SWL.GY--TFTKRQHP.GR...RLV......----DPK....A.....QRSWEEEE.....................EE.EEE...AGE..LMPEKRQHPGKRA...P-..------...GGPCGPQGS.-.-CGQTS.................
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A0A087Y6U4_POEFO/6-234               ............................................LLVLASFVICNL.AVCDGQGLPAED.EM.DRST......TIDNL.mLQRAQS.LLLRSILKKLQDGDG.K..N..DGI.............L............S........Q..........PQWVTKRQHPGK.....RYFE........D.LE..K..RQHPGR.R.E..V..V........D...DEQ.........FW.DMQKRQHPGKREDE...........................MH.SFT.E.FQKRQHPGKR.ST....T.G....H.IP.DSP..--V.VVLSELSKRQHP.GK...RYLv....lHSKRQHP....G.....KRLFEDEDge................adwTE.DGE...EDM..TELEKRQHPGKRF...WD..NSSPELs.tSSPCDVLDS.D.SCSKTS.................
A0A091IDK5_CALAN/7-227               ...........................................p-LLLLCLTLCGV.CLSGEQPLPEAS.EN.MKRS......PLDDI..LQRSQS.LFLQSFLKKAEKKED.I..N..KES.............D............A.......pL..........PEWLAKRQHPGR.....KFLS........D.LE..K..RQHPGK.R.D..A..E........E...EKP.........YG.DIHNWQHPGKREIEd.........................dLN.SYL.E.LKKRQHPGRR.SV....L.E....Q.YA.DIS.sAQL.TYLNEISKRQHP.GR...RYL......MYKHQHP....R.....KRGWNV--.....................-E.ADL...ND-..QYGEEHQHAGKRD...WN..SDSPDD...ASPCHFQDS.S.TSSKGS.................
#=GC seq_cons                        .............................................LlhhsLsls.h.slstGps.Pt.s.pp.ttt.......slDDl..LppuEp.LlLpp.Lp+hpp-pt.t..s..pt..............t............t........Q..........s-WloKRQHPGK.....R..p........-.hE..c......Gc.c.-..t..-........E...-tt.........hh.s.pKRQHPG+RE-p...........................ht.s.h.p..pKRQHPG+R.o...................s....l.sh..ploKRQHP.G+...Rhl..........p......u.....pRshc-........................t..p....ps......EKRQHPGKRh...h............suPCs..ts....Csps..................
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