GenomeNet

Database: Pfam
Entry: TetR_C_17
LinkDB: TetR_C_17
Original site: TetR_C_17 
#=GF ID   TetR_C_17
#=GF AC   PF17922.4
#=GF DE   Tetracyclin repressor-like, C-terminal domain
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   ECOD:EUF00742
#=GF GA   26.10 26.10;
#=GF TC   26.10 26.10;
#=GF NC   26.00 26.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0174
#=GF RN   [1]
#=GF RM   15944459
#=GF RT   The TetR family of transcriptional repressors.
#=GF RA   Ramos JL, Martinez-Bueno M, Molina-Henares AJ, Teran W, Watanabe
#=GF RA   K, Zhang X, Gallegos MT, Brennan R, Tobes R;
#=GF RL   Microbiol Mol Biol Rev. 2005;69:326-356. 
#=GF RN   [2]
#=GF RM   16862575
#=GF RT   Crystal structure of YfiR, an unusual TetR/CamR-type putative
#=GF RT   transcriptional regulator from Bacillus subtilis.
#=GF RA   Rajan SS, Yang X, Shuvalova L, Collart F, Anderson WF;
#=GF RL   Proteins. 2006;65:255-257.
#=GF RN   [3]
#=GF RM   7707374
#=GF RT   The complex formed between Tet repressor and tetracycline-Mg2+
#=GF RT   reveals mechanism        of antibiotic resistance.
#=GF RA   Kisker C, Hinrichs W, Tovar K, Hillen W, Saenger W;
#=GF RL   J Mol Biol. 1995;247:260-280.
#=GF DR   INTERPRO; IPR041612;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   TetR family regulators are involved in the transcriptional
#=GF CC   control of multidrug efflux pumps, pathways for the biosynthesis
#=GF CC   of antibiotics, response to osmotic stress and toxic chemicals,
#=GF CC   control of catabolic pathways, differentiation processes, and
#=GF CC   pathogenicity [1]. The TetR proteins identified in overm ultiple
#=GF CC   genera of bacteria and archaea share a common helix-turn-helix
#=GF CC   (HTH) structure in their DNA-binding domain. However, TetR
#=GF CC   proteins can work in different ways: they can bind a target
#=GF CC   operator directly to exert their effect (e.g. TetR binds Tet(A)
#=GF CC   gene to repress it in the absence of tetracycline), or they can
#=GF CC   be involved in complex regulatory cascades in which the TetR
#=GF CC   protein can either be modulated by another regulator or TetR can
#=GF CC   trigger the cellular response [1]. This entry represents the
#=GF CC   C-terminal domain present in Yfir transcription regulator
#=GF CC   proteins found in Bacillus subtilus [2]. TetR regulates the
#=GF CC   expression of the membrane-associated tetracycline resistance
#=GF CC   protein, TetA, which exports the tetracycline antibiotic out of
#=GF CC   the cell before it can attach to the ribosomes and inhibit
#=GF CC   protein synthesis [3]. TetR blocks transcription from the genes
#=GF CC   encoding both TetA and TetR in the absence of antibiotic. The
#=GF CC   C-terminal domain is multi-helical and is interlocked in the
#=GF CC   homodimer with the helix-turn-helix (HTH) DNA-binding domain
#=GF CC   [3].
#=GF SQ   256
#=GS A0A1N6YMW7_9BACT/117-188  AC A0A1N6YMW7.1
#=GS A0A5C8M981_9BACL/104-182  AC A0A5C8M981.1
#=GS A0A1D9P388_9FIRM/84-181   AC A0A1D9P388.1
#=GS A0A6G8FI12_9MICO/85-179   AC A0A6G8FI12.1
#=GS A0A3B0BZ12_9BACL/120-182  AC A0A3B0BZ12.1
#=GS R9K9T8_9FIRM/83-178       AC R9K9T8.1
#=GS A0A0M0X8M0_9BACI/81-178   AC A0A0M0X8M0.1
#=GS D9WB30_9ACTN/108-193      AC D9WB30.1
#=GS A0A0Q7J3R7_9BACL/104-182  AC A0A0Q7J3R7.1
#=GS A0A2V3W8R1_9BACI/86-183   AC A0A2V3W8R1.1
#=GS G8QX46_SPHPG/83-178       AC G8QX46.1
#=GS A0A3A8WM28_9BACT/109-202  AC A0A3A8WM28.1
#=GS A0A5C8IB74_9MICO/223-297  AC A0A5C8IB74.1
#=GS R5C0H4_9FIRM/83-177       AC R5C0H4.1
#=GS A0A0A2TFN5_9BACI/97-188   AC A0A0A2TFN5.1
#=GS E0S1A0_BUTPB/89-187       AC E0S1A0.1
#=GS A0A0U1NRS8_9BACI/89-187   AC A0A0U1NRS8.1
#=GS D3E5L5_GEOS4/86-186       AC D3E5L5.1
#=GS A0A3S1DKG4_9BACL/83-180   AC A0A3S1DKG4.1
#=GS A0A1H7XTU8_9BACT/110-183  AC A0A1H7XTU8.1
#=GS A0A0Q5M9D7_9MICO/85-175   AC A0A0Q5M9D7.1
#=GS A0A401HWP3_9BACL/84-180   AC A0A401HWP3.1
#=GS A0A0M0WBJ8_9BACI/99-188   AC A0A0M0WBJ8.1
#=GS A0A037Z469_CLOTT/86-187   AC A0A037Z469.1
#=GS A0A416EPN7_9FIRM/83-177   AC A0A416EPN7.1
#=GS U2T8L6_LEIAQ/84-176       AC U2T8L6.1
#=GS C0Z945_BREBN/114-182      AC C0Z945.1
#=GS A0A1I6BSK0_9BACI/88-187   AC A0A1I6BSK0.1
#=GS A0A235F516_9BACI/90-188   AC A0A235F516.1
#=GS V2UKL1_9GAMM/105-202      AC V2UKL1.1
#=GS A0A417PE87_9CLOT/83-173   AC A0A417PE87.1
#=GS R7N4W8_9FIRM/80-177       AC R7N4W8.1
#=GS A0A1I1IWS6_9FIRM/84-181   AC A0A1I1IWS6.1
#=GS U2EHX6_9FIRM/87-184       AC U2EHX6.1
#=GS A0A5C8LW93_9BACL/89-188   AC A0A5C8LW93.1
#=GS R9JR76_9FIRM/83-180       AC R9JR76.1
#=GS F7KGR0_9FIRM/83-178       AC F7KGR0.1
#=GS A0A3A9ESK3_9BACT/83-178   AC A0A3A9ESK3.1
#=GS A0A4Z0GRW4_9BACL/83-183   AC A0A4Z0GRW4.1
#=GS A0A3L7JR40_9BACI/90-183   AC A0A3L7JR40.1
#=GS N2A285_9FIRM/83-177       AC N2A285.1
#=GS A0A3A9CY24_9BACT/83-180   AC A0A3A9CY24.1
#=GS A0A370GIL6_9BACI/88-187   AC A0A370GIL6.1
#=GS A0A4R4EM07_9BACL/85-181   AC A0A4R4EM07.1
#=GS A0A0Q3WY30_9BACI/91-188   AC A0A0Q3WY30.1
#=GS A0A1M4WB52_9CLOT/83-175   AC A0A1M4WB52.1
#=GS A0A0Q5UX48_9FLAO/111-183  AC A0A0Q5UX48.1
#=GS R9MYU5_9FIRM/83-180       AC R9MYU5.1
#=GS R6ZHB8_9FIRM/83-180       AC R6ZHB8.1
#=GS A0A1B1YZJ3_9BACI/88-188   AC A0A1B1YZJ3.1
#=GS A0A6N9Q2S9_9BACL/93-188   AC A0A6N9Q2S9.1
#=GS A0A1I5RRH1_9FIRM/84-195   AC A0A1I5RRH1.1
#=GS A0A2Y9BJW2_9FIRM/83-188   AC A0A2Y9BJW2.1
#=GS V6M697_9BACL/86-185       AC V6M697.1
#=GS A0A1X0WGS4_9GAMM/99-195   AC A0A1X0WGS4.1
#=GS N2A8A6_9FIRM/83-177       AC N2A8A6.1
#=GS I4AG32_BERLS/109-183      AC I4AG32.1
#=GS A0A1G6HLE0_9LACO/88-188   AC A0A1G6HLE0.1
#=GS B1CC44_9FIRM/80-176       AC B1CC44.1
#=GS S2KRI3_9FIRM/83-180       AC S2KRI3.1
#=GS A0A075R0H2_BRELA/86-187   AC A0A075R0H2.1
#=GS A0A4Q9DL75_9BACL/108-183  AC A0A4Q9DL75.1
#=GS A0A369B1R8_9ENTE/86-190   AC A0A369B1R8.1
#=GS A0A2V5KBX3_9BACL/79-179   AC A0A2V5KBX3.1
#=GS A0A1K1R3Z2_9BACT/124-182  AC A0A1K1R3Z2.1
#=GS A0A3G9IXN7_9BACL/106-180  AC A0A3G9IXN7.1
#=GS A0A1H3XUR6_9FIRM/83-177   AC A0A1H3XUR6.1
#=GS A0A0Q3W4J9_9BACI/106-181  AC A0A0Q3W4J9.1
#=GS A0A0F5R0J0_9BACL/91-187   AC A0A0F5R0J0.1
#=GS A0A5C8NVD7_9BACI/81-172   AC A0A5C8NVD7.1
#=GS A0A1C1A5P7_9BACL/106-180  AC A0A1C1A5P7.1
#=GS A0A3N9UI39_9BACI/86-198   AC A0A3N9UI39.1
#=GS A0A0C1R2M3_9CLOT/86-181   AC A0A0C1R2M3.1
#=GS A0A4R4E9U2_9BACL/88-187   AC A0A4R4E9U2.1
#=GS A0A2W1LC98_9BACL/105-182  AC A0A2W1LC98.1
#=GS A0A369BDB1_9BACL/85-184   AC A0A369BDB1.1
#=GS A0A1H7QLR6_9FIRM/84-181   AC A0A1H7QLR6.1
#=GS K0AXQ3_GOTA9/86-177       AC K0AXQ3.1
#=GS A0A1T4N858_9FIRM/83-178   AC A0A1T4N858.1
#=GS A0A1G8RU15_9BACI/108-182  AC A0A1G8RU15.1
#=GS A0A3A9A452_9BACT/83-178   AC A0A3A9A452.1
#=GS A0A4Y3TQN3_9PROT/101-195  AC A0A4Y3TQN3.1
#=GS A0A4Q8R0Y8_9BRAD/86-185   AC A0A4Q8R0Y8.1
#=GS A0A1G7KQG6_9SPHI/113-185  AC A0A1G7KQG6.1
#=GS A0A0K8PAT3_9CHLR/82-177   AC A0A0K8PAT3.1
#=GS A0A1M6K4Z2_9FIRM/83-178   AC A0A1M6K4Z2.1
#=GS A0A401UID7_9CLOT/85-186   AC A0A401UID7.1
#=GS I8UFF6_9BACI/98-187       AC I8UFF6.1
#=GS A0A1G7EKM1_9BACL/83-180   AC A0A1G7EKM1.1
#=GS A0A265Q6B4_9FIRM/86-187   AC A0A265Q6B4.1
#=GS A0A2H5XMQ8_9BACT/93-187   AC A0A2H5XMQ8.1
#=GS A0A417U6X2_9FIRM/83-180   AC A0A417U6X2.1
#=GS G8PA84_PEDCP/88-186       AC G8PA84.1
#=GS W1I2K5_KLEPN/7-72         AC W1I2K5.1
#=GS A0A239IBI3_9FIRM/83-178   AC A0A239IBI3.1
#=GS A0A1I5GZ60_9FIRM/86-183   AC A0A1I5GZ60.1
#=GS A0A6I4VRQ5_9BACL/86-187   AC A0A6I4VRQ5.1
#=GS A0A0Q3WBD0_9BACI/91-188   AC A0A0Q3WBD0.1
#=GS A0A1V4IWE2_9CLOT/96-190   AC A0A1V4IWE2.1
#=GS A0A229URJ0_9BACL/82-181   AC A0A229URJ0.1
#=GS A0A1Z4R9C8_9CYAN/82-182   AC A0A1Z4R9C8.1
#=GS A0A0A8X4Q1_9BACI/92-189   AC A0A0A8X4Q1.1
#=GS A0A1E5LG53_9BACI/100-188  AC A0A1E5LG53.1
#=GS A0A1I7K3W8_9FIRM/84-181   AC A0A1I7K3W8.1
#=GS A0A552U8C3_9SPHN/112-185  AC A0A552U8C3.1
#=GS A0A0R2B718_LACCL/88-186   AC A0A0R2B718.1
#=GS A0A1H0XWG9_9BACI/98-187   AC A0A1H0XWG9.1
#=GS A0A1C7I9K2_9FIRM/83-177   AC A0A1C7I9K2.1
#=GS A0A081P1Y3_9BACL/113-182  AC A0A081P1Y3.1
#=GS A0A1H0EHA2_9RHIZ/123-193  AC A0A1H0EHA2.1
#=GS A0A168Q2Y5_9BACL/108-182  AC A0A168Q2Y5.1
#=GS A0A1X7JNQ4_9BACL/85-186   AC A0A1X7JNQ4.1
#=GS C0D9U7_9FIRM/83-177       AC C0D9U7.1
#=GS A0A0Q3TA52_9BACI/91-187   AC A0A0Q3TA52.1
#=GS W1SG42_9BACI/85-184       AC W1SG42.1
#=GS A0A7D3XPL0_9BACL/86-187   AC A0A7D3XPL0.1
#=GS K6CI36_9BACI/96-190       AC K6CI36.1
#=GS A0A2Y9BE56_9FIRM/83-177   AC A0A2Y9BE56.1
#=GS A0A059NXE5_9BACI/100-187  AC A0A059NXE5.1
#=GS A0A3A1R0V8_9BACI/91-188   AC A0A3A1R0V8.1
#=GS S0K2J5_9ENTE/88-186       AC S0K2J5.1
#=GS A0A2D2MDE2_9PSED/112-181  AC A0A2D2MDE2.1
#=GS R9JBL3_9FIRM/83-180       AC R9JBL3.1
#=GS A0A385NPC9_9BACI/89-187   AC A0A385NPC9.1
#=GS E0IFV7_9BACL/120-183      AC E0IFV7.1
#=GS A0A430B6U6_9ENTE/87-187   AC A0A430B6U6.1
#=GS A5HZG4_CLOBH/86-187       AC A5HZG4.1
#=GS A9B5Y1_HERA2/90-194       AC A9B5Y1.1
#=GS A0A0A1MBX9_9BACI/85-184   AC A0A0A1MBX9.1
#=GS E0IF07_9BACL/106-177      AC E0IF07.1
#=GS A0A2K4ZJB4_9FIRM/83-180   AC A0A2K4ZJB4.1
#=GS A0A2V3VYX6_9BACI/87-185   AC A0A2V3VYX6.1
#=GS A8MG79_ALKOO/86-187       AC A8MG79.1
#=GS I0JTB1_HALH3/101-188      AC I0JTB1.1
#=GS A0A3G3K6I3_9BACL/147-246  AC A0A3G3K6I3.1
#=GS A0A265Q4V1_9FIRM/127-225  AC A0A265Q4V1.1
#=GS A0A0P6WDX2_9BACI/90-188   AC A0A0P6WDX2.1
#=GS I4D6T6_DESAJ/83-178       AC I4D6T6.1
#=GS R6CDX1_9CLOT/83-180       AC R6CDX1.1
#=GS A0A143XVJ9_9FIRM/83-177   AC A0A143XVJ9.1
#=GS A0A0R2FWU6_9LACO/88-187   AC A0A0R2FWU6.1
#=GS A0A3A9GPA3_9FIRM/83-179   AC A0A3A9GPA3.1
#=GS A0A0D1W3Z6_ANEMI/86-187   AC A0A0D1W3Z6.1
#=GS A0A562SHZ5_CHIJA/114-184  AC A0A562SHZ5.1
#=GS A0A2V5K8L1_9BACL/91-190   AC A0A2V5K8L1.1
#=GS F5LH15_9BACL/83-184       AC F5LH15.1
#=GS A0A1H9G1P7_9FIRM/97-194   AC A0A1H9G1P7.1
#=GS A0A2S5TSX2_9RHIZ/119-212  AC A0A2S5TSX2.1
#=GS A0A0A5GE56_9BACI/87-186   AC A0A0A5GE56.1
#=GS R6QP33_9FIRM/108-202      AC R6QP33.1
#=GS A0A371AUN1_9FIRM/101-193  AC A0A371AUN1.1
#=GS M8DBB2_9BACL/86-187       AC M8DBB2.1
#=GS G8LZZ5_HUNCD/87-187       AC G8LZZ5.1
#=GS I8AN16_9BACI/96-187       AC I8AN16.1
#=GS G2TPV5_BACCO/88-184       AC G2TPV5.1
#=GS A0A5S5C7P0_9BACL/108-183  AC A0A5S5C7P0.1
#=GS A6CHJ4_9BACI/90-188       AC A6CHJ4.1
#=GS A0A2V1HE19_9GAMM/105-202  AC A0A2V1HE19.1
#=GS A0A1G5XP32_9FIRM/83-180   AC A0A1G5XP32.1
#=GS A0A1T5M8N6_9CLOT/86-182   AC A0A1T5M8N6.1
#=GS A0A4V3TV16_9ENTE/85-182   AC A0A4V3TV16.1
#=GS A0A4R3L2E2_9BACL/69-185   AC A0A4R3L2E2.1
#=GS A0A4R4EF02_9BACL/93-187   AC A0A4R4EF02.1
#=GS A0A4Q4IIC0_9BACL/83-183   AC A0A4Q4IIC0.1
#=GS A0A6L3UYZ5_9BACI/89-190   AC A0A6L3UYZ5.1
#=GS A0A3A8ZKA3_9BACT/83-180   AC A0A3A8ZKA3.1
#=GS H6NIV2_9BACL/105-182      AC H6NIV2.1
#=GS A0A0M4LAK4_9MICC/87-183   AC A0A0M4LAK4.1
#=GS A0A3M8DN46_9BACL/118-180  AC A0A3M8DN46.1
#=GS A0A398CKI4_9BACL/120-183  AC A0A398CKI4.1
#=GS A0A3A8Y5A8_9BACT/83-179   AC A0A3A8Y5A8.1
#=GS A0A3S9UZS2_9BACL/86-187   AC A0A3S9UZS2.1
#=GS A0A559JIR0_9BACL/88-187   AC A0A559JIR0.1
#=GS A0A516KC06_9BACI/96-188   AC A0A516KC06.1
#=GS A0A4P5PFK0_9ENTE/88-185   AC A0A4P5PFK0.1
#=GS C6CYI0_PAESJ/91-191       AC C6CYI0.1
#=GS A0A1A5YMR8_9BACL/99-198   AC A0A1A5YMR8.1
#=GS A0A1X7HN65_9BACL/87-188   AC A0A1X7HN65.1
#=GS A0A2P8HDA5_9BACT/120-193  AC A0A2P8HDA5.1
#=GS A0A1H8IZS7_9BACI/96-188   AC A0A1H8IZS7.1
#=GS A0A2I0CRX2_9PSED/112-181  AC A0A2I0CRX2.1
#=GS A1BFU6_CHLPD/110-185      AC A1BFU6.1
#=GS A0A0C2QLT3_9BACL/105-182  AC A0A0C2QLT3.1
#=GS A0A0V8IRQ9_9BACI/96-186   AC A0A0V8IRQ9.1
#=GS R9GUW9_9SPHI/110-185      AC R9GUW9.1
#=GS A0A3A9FMK2_9BACT/83-179   AC A0A3A9FMK2.1
#=GS A0A3Q9I766_9BACL/85-184   AC A0A3Q9I766.1
#=GS A0A2Z2KR59_9BACL/83-180   AC A0A2Z2KR59.1
#=GS A0A4Q1SQQ5_9BACL/85-184   AC A0A4Q1SQQ5.1
#=GS A0A3A9B1H1_9BACT/83-180   AC A0A3A9B1H1.1
#=GS A0A2D1SXY9_9BACL/504-604  AC A0A2D1SXY9.1
#=GS K6DT59_9BACI/88-187       AC K6DT59.1
#=GS A0A1X7GXG4_9BACL/83-180   AC A0A1X7GXG4.1
#=GS A0A5S9IMZ3_9BACT/81-180   AC A0A5S9IMZ3.1
#=GS H3SGS0_9BACL/109-182      AC H3SGS0.1
#=GS A0A231R6M3_9BACL/85-184   AC A0A231R6M3.1
#=GS A0A1M7ZPN2_9RHIZ/150-243  AC A0A1M7ZPN2.1
#=GS A0A559JIU0_9BACL/85-184   AC A0A559JIU0.1
#=GS A0A1Y4IR06_9FIRM/83-177   AC A0A1Y4IR06.1
#=GS A0A3L7JZ83_9BACI/112-205  AC A0A3L7JZ83.1
#=GS T0MXM1_9CLOT/86-185       AC T0MXM1.1
#=GS A0A3A9F116_9BACT/82-176   AC A0A3A9F116.1
#=GS C0Z4K7_BREBN/86-187       AC C0Z4K7.1
#=GS A0A1S2R458_9BACI/97-188   AC A0A1S2R458.1
#=GS A0A1Y4F097_9FIRM/83-186   AC A0A1Y4F097.1
#=GS A0A0J1F610_9FIRM/83-178   AC A0A0J1F610.1
#=GS A0A081P5G1_9BACL/86-187   AC A0A081P5G1.1
#=GS A0A1G4VF23_9FIRM/78-176   AC A0A1G4VF23.1
#=GS A0A1I7G8U0_9FIRM/84-181   AC A0A1I7G8U0.1
#=GS A0A1G5HQA8_9FIRM/84-182   AC A0A1G5HQA8.1
#=GS A0A6G1X4U7_9BACI/96-187   AC A0A6G1X4U7.1
#=GS A0A1I0CU66_9BACL/88-187   AC A0A1I0CU66.1
#=GS A0A0J6D1C7_9BACI/94-187   AC A0A0J6D1C7.1
#=GS A0A0R1MAA2_9LACO/88-187   AC A0A0R1MAA2.1
#=GS A0A1I7KVY2_9BACL/88-187   AC A0A1I7KVY2.1
#=GS A0A1I6BTF7_9BACI/95-189   AC A0A1I6BTF7.1
#=GS A0A0Q3SAZ6_9BACI/99-188   AC A0A0Q3SAZ6.1
#=GS A0A024QGS0_9BACI/83-184   AC A0A024QGS0.1
#=GS A0A6M1UEV5_9BACL/74-186   AC A0A6M1UEV5.1
#=GS A0A3S1JQD6_9BACL/129-228  AC A0A3S1JQD6.1
#=GS A0A0C2UGA2_9BACL/91-186   AC A0A0C2UGA2.1
#=GS A0A1S2R8K4_9BACI/95-188   AC A0A1S2R8K4.1
#=GS U5L516_9BACI/102-189      AC U5L516.1
#=GS A0A084GK41_METID/88-186   AC A0A084GK41.1
#=GS A0A370G2B2_9BACI/91-188   AC A0A370G2B2.1
#=GS A0A3A8Y8R5_9BACT/83-179   AC A0A3A8Y8R5.1
#=GS A0A4Y8QAW4_9BACL/88-187   AC A0A4Y8QAW4.1
#=GS A0A1C3RGR6_9PROT/116-183  AC A0A1C3RGR6.1
#=GS A0A235FBX5_9BACI/88-184   AC A0A235FBX5.1
#=GS A0A2N5M8Z4_9BACI/90-201   AC A0A2N5M8Z4.1
#=GS A0A0B0D3F8_9BACI/97-188   AC A0A0B0D3F8.1
#=GS A0A0A8X897_9BACI/98-188   AC A0A0A8X897.1
#=GS R2TCT2_9ENTE/88-186       AC R2TCT2.1
#=GS A0A4R5NBU4_9LACO/88-185   AC A0A4R5NBU4.1
#=GS A0A3A9C7C0_9BACT/83-180   AC A0A3A9C7C0.1
#=GS A0A0M2VWB6_9BACL/1-91     AC A0A0M2VWB6.1
#=GS A0A1C0ZT58_9BACL/109-182  AC A0A1C0ZT58.1
#=GS I3EAW1_BACMM/88-187       AC I3EAW1.1
#=GS R6EE48_9FIRM/83-180       AC R6EE48.1
#=GS A0A0C2UVT8_9BACL/88-187   AC A0A0C2UVT8.1
#=GS A0A1B1Z7A7_9BACI/88-185   AC A0A1B1Z7A7.1
#=GS A0A3A9STN6_9FIRM/84-181   AC A0A3A9STN6.1
#=GS A0A4R1R170_9FIRM/83-175   AC A0A4R1R170.1
#=GS A0A0M2VPG1_9BACL/86-186   AC A0A0M2VPG1.1
#=GS A0A385NJK0_9BACI/106-181  AC A0A385NJK0.1
#=GS V6J017_9BACL/87-183       AC V6J017.1
#=GS A0A178A2Z2_9BACI/86-187   AC A0A178A2Z2.1
#=GS A0A1H0WNY6_9BACI/87-186   AC A0A1H0WNY6.1
#=GS A0A0L0W839_GOTPU/86-185   AC A0A0L0W839.1
#=GS A0A4R1R0X8_9FIRM/83-180   AC A0A4R1R0X8.1
#=GS A0A011A8E9_9BACT/95-184   AC A0A011A8E9.1
#=GS A0A3A9A846_9BACT/83-180   AC A0A3A9A846.1
#=GS A0A1R3TKQ2_9RHIZ/103-196  AC A0A1R3TKQ2.1
#=GS A0A1H8XRT5_9SPHI/112-185  AC A0A1H8XRT5.1
#=GS A0A0L0WC38_GOTPU/86-187   AC A0A0L0WC38.1
#=GS YFIR_BACSU/87-186         AC O31560.1
#=GS YFIR_BACSU/87-186         DR PDB; 1RKT B; 87-186;
#=GS YFIR_BACSU/87-186         DR PDB; 1RKT A; 87-186;
A0A1N6YMW7_9BACT/117-188             ..............................addtnpllrasvvkv-------------.-...-----..---------..---..--...--..-.---.....-...---.-....L.N....R.....L....H....K....A....V....A.NI....VLQGIDRGEFR..P..ETDPQRFSILFVSMVE.GgIML.S.KAYGDN------kylntv...................
A0A5C8M981_9BACL/104-182             ......................pflntavesdhsfpvlrdramda-------------.-...-----..---------..---..--...--..-.---.....-...---.-....Y.L....H.....M....L....S....F....I....Q.GI....LQQGISEKEFR..P..DMDTESVASFIFSSVE.GgIMA.S.RLTRDNK-----hvyy.....................
A0A1D9P388_9FIRM/84-181              ...........................................ml--ALFLKEQKKEI.L...RKKNN..LTVATYEYF..SVN..KV...ST..K.-EN.....P...LKE.K....F.D....T.....A....V....R....I....V....E.KL....IENGIDSGEFY..C..ENPIG-CARNLMYVVE.G.LKI.T.ANTIGITE----etid.....................
A0A6G8FI12_9MICO/85-179              .................................klnaaieaglps-------------.-...GPDDA..LMRLLYEFD..VLA..GK...SP..L.HDQ.....L...VQQ.L....Y.G....E.....Q....L....A....L....F....R.QI....LEEGVESGEFL..L..TGPIEDIAMNFVALED.A.---.-.------------yglhivaggsitv............
A0A3B0BZ12_9BACL/120-182             ......................................rdsalga-------------.-...-----..---------..---..--...--..-.---.....-...---.-....Y.E....Q.....M....S....G....F....M....E.GL....LKQGVASGEFA..P..DMDTESVASFVFSSIE.G.AIM.A.SR----------ltrdnkhvay...............
R9K9T8_9FIRM/83-178                  ...........................................il--DEILNKYENEM.L...DSQSS..LSIAIYEYF..SIL..D-...KT..S.QNN.....T...LYE.Q....Y.L....I.....S....A....N....T....W....K.KL....IQYGMDRHEFN..E..VDRCA-VFDLIVFSYQ.G.VRM.Y.S-----------klmpmdket................
A0A0M0X8M0_9BACI/81-178              ..........................kfvdqlntliykevvdllr-------------.-...--QPS..LVQARAEYF..FSL..--...--..E.DTT.....F...FEQ.R....H.K....R.....V....I....E....G....I....T.NF....LQQGVESGEFA..P..QKDVRSIAHFMLSFVD.G.LML.N.TSQLGET-----snfv.....................
D9WB30_9ACTN/108-193                 ....................................rerptsyql-------------.-...-----..----LTELS..MFA..LR...AP..S.LQA.....A...LQS.H....Y.R....E.....V....T....A....V....T....T.KL....ITEAAERADHE..L..VQPAETIARFFLAGFD.G.LTL.Q.HLSLPDQE----aeqa.....................
A0A0Q7J3R7_9BACL/104-182             ................................pflntavesdhsy-------------.-...-----..---------..---..--...--..-.--P.....I...LRD.RalgaY.E....Q.....M....M....A....F....I....Q.GI....LQKGVDDGEFR..S..DIDTESVASFLFSSIE.GgIMA.S.RLTRDNK-----hvgy.....................
A0A2V3W8R1_9BACI/86-183              .............................................QLNDWISEIVLSI.Q...DKEIN..LVRAKSEFF..LAH..--...NI..E.EVP.....Y...LRE.R....H.E....R.....L....S....H....N....I....Q.QF....INIGIEKGEFQ..K..HIDVSSFCELLISMID.G.VML.H.QYY---------qysssnnls................
G8QX46_SPHPG/83-178                  ............................................l-LNYFLEMIRSDI.Q...CKENR..FSFVIHEFA..F--..-V...EP..T.QSD.....Y...MEK.R....F.E....S.....A....V....Q....I....L....S.RL....LDYGKRTHEFK..-..DFDTRILATHITLFRD.S.IIT.S.SASLKFS-----dtlid....................
A0A3A8WM28_9BACT/109-202             ............................................i-LEDMLEAIKAEI.M...EKELS..LSLAIYEYA..---..--...NL..G.NEE.....F...FTD.I....N.N....K.....A....K....K....R....W....I.SL....LEYGIETKEFQ..P..V-DVEQVSDLILYYYQ.G.LRM.W.SRVISFD-----eqvae....................
A0A5C8IB74_9MICO/223-297             ...............................fsvlvaestavehp-------------.-...-----..---------..---..--...--..-.GHE.....Y...MRR.R....Y.D....K.....L....R....N....R....L....V.GA....LAVGIESGEIR..P..DAPLEELAGALIALMD.G.IQL.Q.WI----------ydrdidm..................
R5C0H4_9FIRM/83-177                  ...........................................il--DEILERYKKEM.L...DSSGS..LSIAILEFY..SEN..QS...DN..-.NDN.....M...LFK.Q....Y.L....Y.....S....K....E....M....W....K.NF....ISYGVERGEFK..K..VDSEEMIDLIIFSYQ-.G.VRM.-.------------fatilpideh...............
A0A0A2TFN5_9BACI/97-188              ....................................kgqqpddem-------------.-...---DP..MAPSNLEFF..ITG..RN...DQ..R.RRE.....Y...GKT.R....Y.Y....T.....G....L....K....I....Y....K.SI....IEKGQENGEFS..K..KFDSDILARSIISFID.G.LAL.D.YSILPPEDVKL-k........................
E0S1A0_BUTPB/89-187                  ...........................................ml--ALFLKEQKKEI.L...RKKNN..LTVATYEYF..SVH..KV...S-..A.KDN.....P...LKN.Q....F.D....T.....A....V....T....I....I....Q.KL....IENGIENDEFY..C..ENPLG-CARNLMYVVE.G.LKI.M.SK----------tcsiteeaidr..............
A0A0U1NRS8_9BACI/89-187              .........................................lcgl-----IDMMEQQL.S...NASDE..LPIVIYEYF..ISG..WK...EQ..E.RRS.....M...LEE.H....Y.K....K.....Q....Q....A....Y....L....V.HY....LQKGVEDGEFN..P..RVDLDVINKMITSYFE.G.VLL.H.TKAAGIGNVRV-k........................
D3E5L5_GEOS4/86-186                  .............................................QLLDWIKKQQEDI.S...LIHHS..LVLARAEFF..LSS.sYD..hAK..Q.EDP.....Y...ITE.R....Y.Q....I.....T....V....E....A....L....C.GV....IRKGQEQGEFR..P..RLEPEAIARYMISFLN.G.LML.D.TFQLGAG-----vtcv.....................
A0A3S1DKG4_9BACL/83-180              ..........................................mmg---HFFKEQKTEL.L...EADNS..MMTATYEFF..LAH..KN...DQ..D.-RS.....F...LQQ.Q....F.E....L.....S....V....S....S....L....T.KA....LEYGVTRNEVH..I..-NNIEQVVRHIILTIE.G.IRI.Y.ALSVGIS-----qhmld....................
A0A1H7XTU8_9BACT/110-183             ................................veaddnvpflkpa-------------.-...-----..---------..---..--...--..-.---.....-...VQK.S....L.K....R.....M....V....A....R....F....H.DI....LVEGQDSGEFN..P..GLPLQELAYTFVALLE.G.GIM.L.AQVTEQKK----yleia....................
A0A0Q5M9D7_9MICO/85-175              .................................qlaaaireglps-------------.-...GPDDA..LMRLLYEFD..VLA..GT...ST..L.HDE.....L...VER.M....Y.R....R.....Q....L....A....T....Y....A.GI....LERGVAAGVFA..P..ALPLETLAMNLVALED.-.---.-.------------ayglhivagn...............
A0A401HWP3_9BACL/84-180              ............................................l-MQRFLAQQKQEL.L...HPSDS..LIIATYEYL..FA-..QR...QQ..L.DPS.....A...LES.R....F.S....A.....A....A....A....Y....L....Q.TI....IQRGIENEEFV..G..N--ASTAAQHIIFCLE.G.LRM.S.STVLALDEAQI-d........................
A0A0M0WBJ8_9BACI/99-188              ......................................mdpyeed-------------.-...--RRK..IIIVHLEFT..LYS..SR...SD..E.INE.....I...LKE.R....G.R....K.....F...fI....Q....L....I....I.EI....IEEGQRLGEFR..R..NVELQVIANMFWTLMD.G.AML.H.TII---------nneypyt..................
A0A037Z469_CLOTT/86-187              .............................................QLTKWIKSQQKSI.E...TINDS..LLLARAQFY..LSSnyTK...DK..N.NFP.....Y...IKE.R....Y.Q....I.....T....V....K....F....I....N.TF....IQKGIDKGEFH..P..SILPESIARYFISSLN.G.LML.D.TFQLGAEVTSV-h........................
A0A416EPN7_9FIRM/83-177              ...........................................il--NEVFQRYESEM.T...DSDRS..LSIAIYEFF..SRP..GM...SQ..G.ENS.....V...LR-.Q....Y.L....L.....S....K....S....M....W....T.EL....IEYGIRTGEFK..R..VDP-EAVYDLIVFSYQ.G.VRM.Y.S-----------rlmkldpa.................
U2T8L6_LEIAQ/84-176                  ......................................lqlaaai---------QEGL.P..sGPDDA..LMRLLYEFD..VLA..GT...SQ..L.HDE.....L...VER.M....Y.L....R.....Q....L....A....T....Y....A.GI....LERGVAAGAFE..P..RLEIATLAMNLVALED.-.---.-.------------ayglhivagns..............
C0Z945_BREBN/114-182                 ......................................hsfpvlr-------------.-...-----..---------..---..--...--..-.--D.....Y...AVA.A....Y.Q....E.....T....I....S....F....M....Q.GL....LEEGISQGEFR..S..EMDAEAVASVIFSSIE.G.AIM.A.SRL---------thdnkhvhf................
A0A1I6BSK0_9BACI/88-187              ........................................sigtl-----FEMLEKQL.Y...EEENT..LYVAIYEYF..IGG..YR...EP..K.RRD.....F...LKA.R....Y.N....R.....Q....N....R....I....L....M.KL....LEKGVNNGEFR..S..DTPILVLEKLLMSFWE.G.LIL.H.STGVGVENL---yvk......................
A0A235F516_9BACI/90-188              ......................................flferfr---------KQVL.T...EQNKQ..ATRVYIEFW..LYS..SR...QE..D.LRN.....V...MEQ.R....Y.E....Q.....F....I....S....Y....I....K.SI....IEEGQKTGEFK..Q..DLDSTQMSQIFWAMRD.G.SGL.H.YSFLGDQK----kyeqt....................
V2UKL1_9GAMM/105-202                 .............eiylynhiqrllqpnkpagcmlivaavncseq-------------.-...-----..---------..---..-T...HD..V.QQK.....V...LEK.R....L.K....E.....K....Q....K....L....L....Q.R-....LQQGIVDGDLA..P..TTPIEEMTDFYTTVIQ.G.LTL.Q.A-----------rdgatqeqlh...............
A0A417PE87_9CLOT/83-173              ..........................................ill---ELLNRYQIEM.L...DSSNC..LTLAIYEFF..STL..QR...-K..G.NES.....L...LYE.Q....Y.L....L.....S....K....K....T....W....E.SL....IAYGIKTKEFN..E..VN-AEAIIDIIIFSYQ.G.VRL.-.------------ysnlml...................
R7N4W8_9FIRM/80-177                  ...........................................vl--ALFLKEQKREL.L...SKKNS..LTVAIYEYY..FEN..K-...TA..P.KQN.....Y...IKK.Q....F.D....I.....A....L....F....I....L....E.KL....IIEGVENGEFY..C..EDPHGAASNMM-YVLE.G.LKA.A.AKT---------rgiteaavd................
A0A1I1IWS6_9FIRM/84-181              ...........................................ml--ALFLKEQKKEI.L...RKKNN..LTVAIYEYY..FVN..K-...VT..D.KDN.....F...LKG.Q....F.D....T.....A....V....R....I....V....E.KL....IENGVETGEFC..C..ENPFG-CARNLMYVVE.G.LKV.M.SKTIGITE----eaid.....................
U2EHX6_9FIRM/87-184                  ................................klikyiewilygq------------L.N...EEARL..NARFTFEFW..SVL..SK...NK..D.TSD.....K...AKE.R....Y.E....L.....F....K....R....D....L....S.DI....LKSGVENGEFK..K..DLDIASMVYIILSSMD.G.MGF.F.------------nsvmdvpin................
A0A5C8LW93_9BACL/89-188              ...........................................tv--AALLDQQKEDL.A...ESSSS..MASVMYEYF..ISG..WR...SE..E.RKA.....Q...LAG.R....Y.A....S.....G....F....G....I....F....T.TL....IEKGIERGEFK..P..TLSVPLIAKIIAAQLD.G.ILT.H.TLAVGHEQAEVE.........................
R9JR76_9FIRM/83-180                  ............................................q-LLLYLDEQKKTI.L...KKKDN..LTAATYEYL..FEN..NF...TA..-.KNN.....P...VKK.Q....F.D....E.....E....A....A....V....L....A.HL....IAEGVAQ-EWM..D..CEDAAEAARNILYTLE.G.LKV.S.ARVMGMTAERV-d........................
F7KGR0_9FIRM/83-178                  ............................................l-LKDYLLSELGEV.Q...DRKPG..LCGAIYEYC..LE-..NR...ET..Q.SPS.....F...MSA.Q....Y.E....R.....G....K....E....L....L....L.KL....LAYGIRTGEFH..L..EEPGEAAS-AVLFMVE.G.VKM.-.------------csevmpiteem..............
A0A3A9ESK3_9BACT/83-178              ............................................i-LEELLSRYANEM.M...DFENS..ISLAIYEFY..SNP..AI...SK..E.E-N.....S...VKK.Q....Y.E....I.....S....K....S....T....W....I.EL....IRYGIDRKEFY..P..VDP-ESIFHVIIFAYQ.G.VRM.Y.SRLMRMDK----di.......................
A0A4Z0GRW4_9BACL/83-183              ........................................kiwda-LQSYLHEVES--.-...EAEDP..FSMAAYEYF..VTG..WR...TE..E.RQN.....Y...MSW.R....Y.G....N.....G....Q....K....I....F....L.RL....FEEGVRRGEFV..P..RQSLEAITRFFINVND.G.IAL.E.ATLLNGKQ----igva.....................
A0A3L7JR40_9BACI/90-183              ............................................a-IDEYLAAIQENF.I...DNELG..FGIVQFEYF..INS..AR...KE..E.RAN.....Y...LLT.R....Y.N....S.....A....V....K....S....F....S.DL....IHHGIQNGEFK..P..IQPVEAIVLFFINVTD.G.LLM.Q.RL----------ltin.....................
N2A285_9FIRM/83-177                  ...........................................il--DEILSKYEKEM.L...DSQSS..LSMAIYEYF..SIG..DI...TN..E.-NH.....M...LYE.Q....Y.L....I.....S....A....N....T....W....K.KL....IQYGIDRHEFN..-..EVDISAVFDLIVFSYQ.G.VRM.-.------------ygklmpvnke...............
A0A3A9CY24_9BACT/83-180              ..........................................ill---LFLQEQKKEL.L...RKNDT..LTQAIYEFY..FQN..QL...-G..K.KDN.....I...LKR.Q....F.D....S.....A....V....K....I....I....E.KL....IETGTDNGEFY..C..EDCKG-TARNIMFVLE.G.LKI.S.AQTIGITAE---avd......................
A0A370GIL6_9BACI/88-187              ..........................kmryllniyshqiernpdw-------------.-...---QN..LIRVHIEFW..LQS..SR...DE..N.LKS.....M...LDD.R....M.K....N.....I....Y....Q....K...lI....I.DI....LELGKKNGEFP..G..NLDSKMISTLFWSIID.G.ISI.Y.YGV---------mkddyp...................
A0A4R4EM07_9BACL/85-181              ...................akeklyklldsieenkkscmlpikml-------------.-...-----..-----IEYY..---..SE...EN..F.IKV.....E...IQK.G....Y.R....E.....Y....V....E....I....L....S.NI....LLEGKNNQEFS..T..IIPEEELSRLLVSTID.G.IVI.H.NSTFEN------nyvi.....................
A0A0Q3WY30_9BACI/91-188              ...................................flfktyrevs------------L.T...EDFKH..LMLVHGEFW..LSS..SR...KK..E.IRS.....I...MLE.R....Y.Q....N.....V....Y....K....S....F....ViAI....LEEGIASGEFR..K..DIDPSVISTIFWTYVD.G.ICL.D.YAVLGTE-----ypyc.....................
A0A1M4WB52_9CLOT/83-175              ...........................................il--DEVLKRYESEM.A...DAGSS..LSVALYEFF..SSP.eYS...GD..D.HSM.....Y...--E.Q....Y.R....Q.....S....A....E....M....W....E.RF....LEYGIKRGEFL..P..VDTEAVIDLILFSYQ-.-.---.-.------------gvrmysklmpvd.............
A0A0Q5UX48_9FLAO/111-183             ...........................eaddthpmlkeaakkall-------------.-...-----..---------..---..--...--..-.---.....-...---.-....-.-....N.....W....K....E....N....L....A.SL....IQKGIDSKEFK..P..ETNPEEAALLMLSIIE.G.TVM.I.SK----------ltgktnylksl..............
R9MYU5_9FIRM/83-180                  ...........................................vl--ALFLKEQKKEL.L...NRKHS..LNKAVYEYF..FEN..P-...VS..S.KDN.....L...LKR.Q....F.D....A.....A....V....Y....I....I....E.KL....IEAGVENGEFY..C..EDSR-GAARNIMYVLE.G.LKI.A.S-----------etrgiseavvd..............
R6ZHB8_9FIRM/83-180                  .........................................ilal----LLKEQKKEL.L...GKEAS..LTKAIYEYY..FAN..QI...-T..G.KDN.....L...LRK.Q....F.D....Q.....A....V....H....V....L....E.KL....IDAGCQSGEFY..C..EDPRGA-ARNIMYVLE.G.LKI.A.ACTRGVSE----amvd.....................
A0A1B1YZJ3_9BACI/88-188              ....................................klanlfkrf--------KKQEL.K...EDDQQ..TMRVYIEFW..LFG..SR...QE..D.LRK.....I...LAE.R....Y.N....R.....F....I....D....Y....I....V.NI....IVEGQQSGEIK..K..EIDPQNISRIFWAIRD.G.NVL.H.YSFLGEEE----qyri.....................
A0A6N9Q2S9_9BACL/93-188              .................................tiygeerqpndd-------------.-...--MNS..LAPSKLEFF..ITG..RN...DK..R.RRE.....F...GKA.R....Y.Y....N.....G....L....K....L....Y....S.AI....IEQGQQKGEFC..T..KFDSDIIARSIIAFID.G.LAF.D.HSILPKEDLK--mk.......................
A0A1I5RRH1_9FIRM/84-195              ...........................................ml--ALFLKEQKKDI.L...RKKNN..LTVATYEYY..SVK..-K...QS..V.KDN.....P...LKV.K....F.D....T.....S....V....R....I....V....E.KL....IENGVDNGEFV..C..ENPLG-CARNLMYVVE.G.LKI.S.SKTIGISE----eaidrelmyvleglvsde.......
A0A2Y9BJW2_9FIRM/83-188              ............................................q-MRHFLNAQKREL.L...NPADS..LIIATYEYL..FAH..SK...VL..D.KAE.....-...MQN.N....F.N....H.....A....G....S....Q....L....R.RI....IQSGVDNGEFS..-..-TDPDAAAQNIVLLLE.G.LRI.S.STVLTLD-----eefleqqmeyilsq...........
V6M697_9BACL/86-185                  .............................................QIISWLDKQRMQI.K...QIDQS..LLVANSEFF..LSV..RE...NK..A.GYP.....Y...ISD.R....Y.Q....R.....L....V....E....V....L....I.AF....IQAGAERGDLA..P..RFPRDSIARYLISFID.G.LML.D.TAHLGQDKTNV-d........................
A0A1X0WGS4_9GAMM/99-195              .........................................vlfs----WIEVHILQF.T...-LMQK..LAKISLDYA..NTH..EH...LT..N.IDK.....A...IKK.F....Y.E....K.....E....S....V....V....L....K.NT....LKEGIAAGEFR..E..VNPA-DMSMFISTFLD.G.VLF.R.TVMF--------pnfkykh..................
N2A8A6_9FIRM/83-177                  ..........................................ild---DILEGYRKEM.L...DSRSS..LSTAIYEYF..SLP..EI...AG..Q.-KN.....A...LYQ.Q....Y.L....I.....S....A....N....T....W....K.KL....IQYGIDRKEFH..-..EVDIEAVFHLIVFSYQ.G.VRM.Y.S-----------klmpvdeg.................
I4AG32_BERLS/109-183                 ..........................itelipnsdnileiatqnk-------------.-...-----..---------..---..--...--..-.---.....-...---.-....-.E....E.....F....E....G....F....F....L.EF....LKKGVENGEVS..P..QKDIESIAAFLFVFYN.G.LKV.-.------------vgkinsskeeleka...........
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A0A417U6X2_9FIRM/83-180              ...........................................il--ALFLKEQKREL.L...TKKGT..LQKACYEFF..FEE..-N...DY..S.REN.....L...LKK.Q....F.D....A.....A....V....M....V....I....Q.RL....IEEGVEIGEFC..C..EEPRRAASN-IMYVLE.G.LKV.A.ANTRGVT-----eaavd....................
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K6DT59_9BACI/88-187                  ............................................v-LISYLQETSQSI.D...HLEDS..VVPAIYEFC..TTG..WR...EE..Q.VRE.....F...FVN.R....Y.I....R.....V....T....A....I....F....I.DV....IGRGVEEGEFK..P..TQSVDEIVKYMISGLD.G.IML.H.SLAFGSQQ----inav.....................
A0A1X7GXG4_9BACL/83-180              ............................................i-LTEFLQQQKEEL.L...NIGST..IRLAIYEFF..LSQ..-K...DN..S.FEG.....I...LEQ.Y....F.N....V.....A....V....A....M....I....S.KT....LSYGIERKEIM..P..-LDTDGMARQIVILLE.G.LTI.M.ALSMS-------vsptlid..................
A0A5S9IMZ3_9BACT/81-180              ................................kmheiidmywafv-------------.-...KNNME..FIRIFMNWF..LQA.eTK...EK..R.KTE.....R...LRK.I....H.R....S.....F....E....E....I....F....V.QC....LQLGIEEGIFD..E..NLNIQNTALSIVSSLE.G.LLV.Q.VIMLGQS-----pedfd....................
H3SGS0_9BACL/109-182                 ............................aiesdhsfpilrdqale-------------.-...-----..---------..---..--...--..-.---.....-...---.A....Y.G....Q.....M....L....S....F....I....Q.GI....LQQGIADGEFQ..P..DMDTEAAASFIFSSIE.GgIMA.S.RLTR--------dnrhvhh..................
A0A231R6M3_9BACL/85-184              ...........................................ll--HGFLQKQKEEL.A...NAKNT..IRAASYEYF..LSR..RR...H-..L.PEE.....V...LGA.Y....F.N....G.....A....V....A....V....F....S.RV....LAYGIERQEMTrlA..HADIEKTARHFVVALE.G.LNV.L.AMSM--------svspeli..................
A0A1M7ZPN2_9RHIZ/150-243             ............................................i-ISAWIEIHIAQF.V...-MLQK..LAKISLDYA..CTS..SR...TL..Q.VDK.....A...IRK.F....Y.D....K.....E....S....V....V....L....S.RA....IRAGVAKGIFR..P..VDPTEA-ATFISTFLD.G.VLF.R.NVM---------fptfd....................
A0A559JIU0_9BACL/85-184              ...........................................af--ERFLGEQEKRA.R...EAVGG..LAPCMFEYL..IVG..RR...DA..N.RRS.....L...IEE.R....H.R....A.....V....Y....G....S....M....F.AL....VQDGLRRGEFQ..P..SKSVETFVHWLVSFLD.G.IFL.E.SIMTGAERIE--la.......................
A0A1Y4IR06_9FIRM/83-177              ............................................i-LNEVLEKYKAEM.L...DGQAS..LSLAIYEYF.sIAD..VS...ET..E.NEL.....Y...--A.Q....Y.L....A.....S....F....K....A....W....K.NL....LDYGIQTGEFN..-..LVDIRPVFDLIIFSYQ.G.V--.-.------------rmysklmpinee.............
A0A3L7JZ83_9BACI/112-205             ............................lnvyslqaeknpewqnn-------------.-...-----..-IRVHIEFW..LQS..SR...DE..K.LKL.....L...LEK.R....M.K....E.....I....Y....Q....Q...lI....F.DI....LEEGKRTGEFS..K..SLDSTLISILFWSIID.G.IST.Y.YG----------vmkddy...................
T0MXM1_9CLOT/86-185                  .........................kltayikwilnwvldeknml-------------.-...-----..QIKFTFEFW..SVT..SR...ND..T.IKA.....F...ALE.R....Y.N....Q.....A....S....T....D....L....C.SL....LKEGVKNGEFR..S..DLDVDSTCYIILSSTD.A.IGF.Y.TGIMEL------katds....................
A0A3A9F116_9BACT/82-176              .........................................ifal----FLKEQKKEI.L...RSKKT..LAAAAYEYA..FAN..PK...--..-.-DT.....T...LKK.Q....F.N....T.....G....V....A....M....L....E.KL....IRMGIENEEFY..D..V-DARIAAKNIMYVLE.G.LKI.A.SLTMGVS-----getvd....................
C0Z4K7_BREBN/86-187                  .............................................QIIKWVNKQQGEI.E...KIDQT..LSKANSEFF..LSL..KD...QQ..K.QQSy...pY...ITT.R....Y.E....K.....L....V....D....V....L....T.AF....FAHGTETGEFK..P..QLPPEVIARYLISVID.G.LML.D.TAHLGPEKTKVS.........................
A0A1S2R458_9BACI/97-188              .....................................edrepddk-------------.-...--MDP..LAPSHLEFF..ITG..RN...DK..R.RRK.....Y...GKE.R....Y.N....Y.....G....I....N....L....Y....T.DI....IRAGQESGEFS..N..THDSDIIARSIVTFID.G.LAI.G.HAILPTEDLK--mk.......................
A0A1Y4F097_9FIRM/83-186              ...........................................il--DEILNRYKCEM.T...DSENS..LSLAIYEYY..SEK..QA...DA..E.NNM.....L...L-K.Q....Y.E....S.....S....V....N....M....W....Q.DF....LSYGIQRGEFR..N..IDCEEVIDIIIFSYQ-.G.VRM.Y.SSV---------llpsekiaeriishi..........
A0A0J1F610_9FIRM/83-178              ...........................................if--EHYLAHERNAI.F...SDNRG..LFLATHEFA..F--..-V...EP..E.QRA.....Y...FDK.R....V.E....L.....S....V....E....L....L....S.TL....LLYGQEAGEFK..-..NFDVSVVAMHIIYFFD.G.LKT.S.SSVLTIT-----eemvd....................
A0A081P5G1_9BACL/86-187              .............................................QLTDWVNRQPHSL.K...TVGQT..LLLAKAEFF..LSSgyRR...NK..E.SFP.....Y...IAQ.R....Y.L....R.....I....K....E....A....I....E.SV....VIKGTERGEFR..P..RLSPEAVALYFVSFMD.G.LML.D.TFQLGAETTLV-e........................
A0A1G4VF23_9FIRM/78-176              ............................................a-LAIFLNELKKEI.L...NKDND..LSVAVYEYL..FLK..YA...DG..E.NAD.....A...LKN.H....Y.A....A.....K....V....D....T....L....T.KI....LEEGSDSGELY..C..EDCALT-ARNIMYTLE.G.LKV.A.AHTFGVTEKEV-e........................
A0A1I7G8U0_9FIRM/84-181              ...........................................ml--ALFLKEQKKEI.L...RKKNN..LTVATYEYF..SVN..KV...SP..K.D-N.....P...LKE.Q....F.D....T.....A....V....R....I....I....E.RL....IENGIESGEFY..C..ENPLG-CARNLMYVVE.G.LKI.T.SKTVGISEE---aid......................
A0A1G5HQA8_9FIRM/84-182              ...........................................ml--ALFLKEQKKSI.L...RKKNN..ITIATYEYF..FNH..KV...SS..K.-DN.....P...LKK.Q....F.N....T.....A....V....T....I....V....E.KL....VENGIENGEFY..C..ENPLG-FARNLMYVVE.G.LKI.M.SK----------tcsiseeaidn..............
A0A6G1X4U7_9BACI/96-187              ....................................ksrnpdakm-------------.-...---DP..LAASKLEFF..ITG..RN...DD..R.RRA.....Y...GQK.R....Y.K....L.....G....V....R....L....Y....A.DV....IKAGQDAGEFS..D..RHDHELLAKSIITFID.G.LAL.D.DAILPEDEVQI-e........................
A0A1I0CU66_9BACL/88-187              ............................................m-IETLFARQQQEL.E...QAEGG..LMSAFYEYF..LVG..WR...YP..D.RRE.....V...LTR.R....Y.E....R.....G....I....E....R....F....A.QI....LQTGVSRGEFV..P..AMPVQDISRLVASFQE.G.IVA.H.THAVGATKAN--ta.......................
A0A0J6D1C7_9BACI/94-187              ...................................fgekmepndr-------------.-...--MDP..LAPSNLEFF..ITG..RN...DE..R.RRA.....Y...GEE.R....Y.Q....I.....G....V....R....V....Y....E.DV....IKAGQESGEFS..R..KYKSSTLARTIVSFVD.G.LAL.D.YAILSKEQIQ--lk.......................
A0A0R1MAA2_9LACO/88-187              ............................................v-LDKYLELQKERL.L...NISKS..LLMSGYEYY..S--..EN...SE..E.ATQ.....F...LGK.N....L.D....E.....M....R....R....T....I....L.GV....LNLGVEQKKIH..-..QEDLPTIGDHFILTIE.G.LSV.-.------------fcylhqasekyideql.........
A0A1I7KVY2_9BACL/88-187              ............................................v-VEEFIEMAEHEL.P...NVTHD..IGPVVYEVL..MGS..WR...DE..E.KRA.....L...AKQ.R....Y.Q....Q.....T....V....D....M....Y....V.SI....LQHGVESGEFR..P..ILPIEDIAKSTLSFID.G.LTL.H.ILHLGRESIN--lr.......................
A0A1I6BTF7_9BACI/95-189              ......................................tyldfep------------F.A...EKNKA..NVLVHYEFK..LHS..SR...SE..E.LLA.....Y...LKK.R....R.Q....Q....yF....I....D....L....V....A.DI....IEDGQSKGDVK..K..ELNARLYAEMFWSILD.G.VTL.Q.TVYD--------dypyhea..................
A0A0Q3SAZ6_9BACI/99-188              ......................................rvpndrm-------------.-...---DP..LAPVTLEFF..ITG..RN...DE..R.RKR.....Y...GQE.R....Y.F....Y.....G....T....K....I....F....S.DV....IKEGQKNKEFS..K..KYDSEVLARMIVSFID.G.LAL.D.YAILSAEE----imme.....................
A0A024QGS0_9BACI/83-184              .............................................QLTTWIKDQKKSI.Q...FNRDS..LILARSEFF..LST.kYK..mDK..E.NAS.....Y...LKK.R....Y.E....L.....M....I....E....V....I....K.ET....IQLGEANGEFN..P..IVSKDAIAQFIISCID.G.LML.N.TFQHGSAVT---nte......................
A0A6M1UEV5_9BACL/74-186              ..............................gyaklldryrnawet-IEHFLRYQEKEI.G...NTHRS..LSPAIFEFF..SSG..WR...DA..D.RQP.....F...LVG.R....Y.K....R.....A....V....G....D....F....A.RF....LRAGVKRGDFR..P..LQEPEAIAQFVISFLD.G.LSV.D.VLLLGSE-----vcdy.....................
A0A3S1JQD6_9BACL/129-228             ............................................a-LDRLLTEQKKAM.N...TLENS..LASAYYEYF..LSG..YR...DK..D.RRI.....R...LIR.H....Y.D....A.....A....L....G....N....I....I.RL....IEAGIAKGEFR..P..TLPTQLIGKIMTSNLE.G.IMS.L.AMAVGTAQAE--aa.......................
A0A0C2UGA2_9BACL/91-186              .............................hlfakfyrqsldelrk-------------.-...-----..WLPFQMEFT..IYA..GR...QP..E.LTN.....L...LSV.Q....M.S....K.....A....L....S....L....I....Q.GI....IEEGKRSGEFK..P..DLDARSAAELFWSVRD.G.LAV.H.FMLGGEET----eyk......................
A0A1S2R8K4_9BACI/95-188              ..................................ykerpqtsewr-------------.-...----N..IISVHMDFW..INS..AK...QD..K.LGE.....I...MKN.R....Y.K....E.....Q....Y....R....L....F...mA.DI....IEEGKKKGEFK..K..EVSSEVAGSLFWAMID.G.ICL.H.YSVVAED-----yayte....................
U5L516_9BACI/102-189                 ........................................dkdmk-------------.-...----D..YIVVHYEFT..LHS..SR...NE..E.ISR.....V...LKQ.R....G.N....Q.....F...fI....D....L....I....L.KI....VEEGKESGEFA..A..ETDSRLIANMFWVVVD.G.TNI.Q.RILFD-------dfpsdkv..................
A0A084GK41_METID/88-186              ...........................klrqffknyleiklspdw-------------.-...---QR..MIGVHLEFW..IHS..GR...DE..E.LKR.....V...MTA.R....Y.E....E.....V....Y....R....T...lL....M.EV....LQEGIDQLEFR..P..DADPAIISSLVWGTID.G.TCL.H.YSVIGND-----yp.......................
A0A370G2B2_9BACI/91-188              ................................latflgdkklpnd-------------.-...-KMDP..LAPSKLEYF..ITG..RN...EK..R.RQD.....H...AKK.R....F.Q....K.....G....Y....M....I....T....Q.RI....IEEGVKAGEFT..P..KFDPGVIAKSIISHID.G.MAI.D.HAILGSETIQL-k........................
A0A3A8Y8R5_9BACT/83-179              ...........................................il--DEILNKYENEM.L...DSQSS..LSIAIYEYF..SIR..DI...AN..-.QSN.....T...LYE.Q....Y.L....I.....S....A....N....T....W....K.KL....LQYGMDRHEFN..-..EVDISAVFDLVVFSYQ.G.VRM.Y.SKLMPMD-----ketp.....................
A0A4Y8QAW4_9BACL/88-187              ............................................m-LEAMLTGQKADL.A...GVDTG..LQPVFHEYF..LTG..WR...DA..G.RRR.....R...LVQ.R....Y.A....Q.....G....V....A....R....F....V.RL....LEAGAERGEFA..P..SLPLELIAQIAASHIE.G.IMT.H.ALALGAQQAA--aa.......................
A0A1C3RGR6_9PROT/116-183             ................................hdavikaqvqdnl-------------.-...-----..---------..---..--...--..-.---.....-...---.-....-.V....E.....I....A....E....T....F....C.GV....IEEGIANGEFK..T..TEPAENIARFLTSTVQ.G.LRV.M.AKSSTTK-----etltt....................
A0A235FBX5_9BACI/88-184              ...................................ikmivldfkn------------A.E...HSDNQ..FAAAQVEFN..ILS..RN...SS..N.AKE.....F...LQR.R....Y.Q....W.....A....S....D....F....L....C.SL....INEGIKRGEFS..P..NAPVHHIARYYITFFD.G.LSI.E.SIFLKSQE----lns......................
A0A2N5M8Z4_9BACI/90-201              .............................................AIENYLAEVEAGL.L...EPGVG..FGIVQFEYF..VFS..TR...KE..E.RSS.....Y...LLK.R....G.E....T.....A....I....R....N....F....S.LL....IENGMKTGEFK..P..IQPTEAIVMFIININD.G.LLL.Q.SLTLNK------yehdrvyvkeqiqglkmy.......
A0A0B0D3F8_9BACI/97-188              ....................................engepddem-------------.-...---DP..MAPSNLEFF..ITG..RN...DH..R.RRE.....Y...GQK.R....Y.K....L.....G....L....K....L....Y....A.NV....IEAGQRSGEFS..Q..KYDSGLIARSIISYID.G.LSL.D.GAILPKEEIQ--lk.......................
A0A0A8X897_9BACI/98-188              .....................................dgepdddm-------------.-...---DP..LSPAKLEFF..IIG..RN...DD..H.RRE.....Y...GKV.R....Y.N....N.....G....L....K....I....Y....A.TI....IEHGQKSGEFS..P..RFDHQIIARSIISFID.G.LAV.E.HAMLSKEDLKI-k........................
R2TCT2_9ENTE/88-186                  ...........................................ll--DTYFNSHKERL.L..nSINDS..ILRAMYEYY..FTH..KS...EE..D.-RE.....F...QQA.Q....M.A....A.....T....K....Q....T....I....Y.EI....LELGVQQGVLT..-..DQPLDTLAENFMFVIE.G.LSV.L.ALIGDITEAQ--id.......................
A0A4R5NBU4_9LACO/88-185              ............................................v-LDQYLTIQKQRL.L...NISKS..LLMSGYEYY..AFE..K-...SA..S.SQE.....F...LTK.S....L.A....D.....T....R....R....T....V....L.GL....LMLGVDQEKMH..D..-QQIEDLADYCILTIE.G.LSL.F.CYLHQA------dekyin...................
A0A3A9C7C0_9BACT/83-180              ...........................................il--RFFLKEQKKEI.L...SQTNT..LTVATYEFF..FAN..KV...S-..K.KEN.....I...IKH.T....F.E....T.....A....V....K....V....L....A.DL....LLAGTESEELY..C..ENPVGTA-RNIMLVLE.G.MKV.A.SHTMGV------sekfvd...................
A0A0M2VWB6_9BACL/1-91                ............................................m---NFFEKQKTEM.V...NMQGS..IRIAVYEYF..LSQ..K-...ND..L.AAD.....L...LKD.Y....F.N....G.....A....V....A....L....V....S.QT....LAYGIDRGEIV..P..L-DTEQTARHIVLVLE.G.LNT.L.A-----------mgtsvp...................
A0A1C0ZT58_9BACL/109-182             ...........................avesdhsfpvlrdhavga-------------.-...-----..---------..---..--...--..-.---.....-...---.-....Y.S....Q.....M....L....G....F....I....Q.SL....LAEGLRTGEFQ..P..EMELESVASFIFSTIE.G.GIM.A.------------grlmrdnrhvay.............
I3EAW1_BACMM/88-187                  ............................................g-VLQFLESQEQEI.M...EVDES..LIPVILEYY..MID..LR...EK..T.KDA.....F...LFN.R....Y.Q....K.....A....V....K....V....V....E.LL....FQKGVVHGEFK..P..VIPISEVARFVVAFLD.G.LIM.E.AIYLGTEEVKIK.........................
R6EE48_9FIRM/83-180                  ..........................................ill---LFLKEQKKEL.L...RKKNT..LTQATYEFY..FEN..-D...LP..K.RDN.....I...LKK.Q....F.D....S.....A....V....K....I....I....E.KL....IEAGVDNGEFL..C..EDC-EGTARNIMFVLE.G.LKI.S.AQTIGVTAE---avd......................
A0A0C2UVT8_9BACL/88-187              ........................................airlm-----FSQVKTDL.A...SSDNN..TDLAFYEFY..ISG..YR...NE..A.RRA.....L...FTR.R....Y.D....Q.....A....I....A....R....I....V.PL....IQLGIDRGELS..P..ILPVELAVKIASSHLD.G.ILI.H.QLAVGPEKTE--sv.......................
A0A1B1Z7A7_9BACI/88-185              ..................................lvkdfedyksa-------------.D...DTEDL..FGAVQIEYF..LIN..RL...LP..E.KKI.....Y...MKE.R....Y.E....F.....A....I....E....H....L....M.NL....FDEGVKKGEFN..P..KYPLDTIARYFITFND.G.INI.A.TIFLNKKD----lnfn.....................
A0A3A9STN6_9FIRM/84-181              ...........................................ml--ALFLKEQKKEI.L...RKKNN..LTVATYEYF..TLH..K-...AA..V.SDN.....P...LKR.Q....F.D....T.....A....V....R....I....V....E.KL....IETGAQSGEFY..C..ENPLG-CARNLMYVVE.G.LKI.T.AGTIGVTE----eaid.....................
A0A4R1R170_9FIRM/83-175              ............................................i-LEEVLSRYKSEM.K...DSGTS..LSVAIYEYY..TAE..KR...EN..N.---.....A...LLM.R....Y.G....A.....S....K....R....M....W....Q.RL....IAYGMERGEFR..-..RVDAEAVYDVIVFSYQ.G.VRM.Y.S-----------kmmpiden.................
A0A0M2VPG1_9BACL/86-186              ............................................r-LTRWVDVQRKSI.E...GINDS..LVRAKAEFF..LTS.kYV...RQ..H.HVP.....F...LEQ.R....Y.N....N.....L....K....D....T....I....K.GF....IEKGVERGEFR..P..RLPADHISLYFISFID.G.LML.N.TFQLKTETTNV-d........................
A0A385NJK0_9BACI/106-181             ........................................lntai-------------.-...-----..---------..---..-E...SD..D.GHP.....L...LKE.R....S.Q....Q.....A....M....KflidR....L....S.MI....IVEGIENKEFR..S..DINPDEVSSYFIAVIE.GgLML.S.KLFDD-------skyir....................
V6J017_9BACL/87-183                  ............................................a-LEDYLQNLES--.-...EASDP..FSIVVYEYF..VTG..WR...TE..E.RRN.....Y...LAR.R....Y.E....N.....G....K....A....I....F....L.RL....FEEGVRRGEFS..P..KQPLEAINSFFINVND.G.ISM.E.ATLLDEKTVRV-a........................
A0A178A2Z2_9BACI/86-187              .............................................QLKNWVEEQRLYI.E...RIDQT..LLYARAEFF..LSSnyAN...DK..D.NFP.....Y...ISE.R....Y.N....R.....I....I....E....A....I....E.EV....LNEGKRKGEFR..P..QQSTRSIARYLISFID.G.LML.D.TFQLGDEQTKVK.........................
A0A1H0WNY6_9BACI/87-186              ............................................g-LDTYLNEVEKAL.I...NSSTS..FASVNLEYF..IIG..RH...AE..G.RRD.....F...ISE.R....Y.K....Q.....A....I....G....H....F....T.KL....LGKGVEQGEFK..P..IQPVDAIANYLINIVD.S.MHI.Q.LLVIDKEQSYI-s........................
A0A0L0W839_GOTPU/86-185              ...........................................kl--INYIHWTLTGLfE...EKIQK..MSRFTFEFW..SVL..AR...NP..N.MSD.....K...AKE.R....Y.K....L.....F....Y....D....D....L....A.EI....LQQGIDCGEFE..K..DIDISSMVYIILSTMD.G.IGY.M.NSV---------mkitithd.................
A0A4R1R0X8_9FIRM/83-180              ...........................................il--ALFLKEQKKEL.L...GKRNN..LTIAVYEFF..FAN..K-...FP..K.KDH.....L...LKQ.Q....F.D....T.....A....V....K....I....I....E.KL....IEAGVDAGEFY..C..EDPLGA-ARNIMYVLE.G.LKV.V.SQ----------trgitedvvd...............
A0A011A8E9_9BACT/95-184              ...............................smsrglekmtdfrf-------------.-...-----..LRMVMIEMH..MKS..AS...KE..E.KKM.....F...VRD.P....A.D....R.....V....R....S....A....M....V.RF....FKRGVDEGAFK..P..-LPPETLEIFFTAAFD.G.LEV.R.------------snfdqnft.................
A0A3A9A846_9BACT/83-180              ............................................i-LTLFLKEQKKEL.L...QNKDN..LTVAVYEYF..FAH..-K...ST..D.KNN.....M...LRK.Q....F.D....A.....G....V....R....V....I....E.KL....IEAGIASGEFY..C..ENPKGAAANI-MYVLE.G.LKI.N.AQTFGITEK---mvd......................
A0A1R3TKQ2_9RHIZ/103-196             ......................................lidvars---------NQDI.P...NVVQA..FAVLNAESL..TT-..--...DH..P.AST.....W...FAL.R....V.S....H.....L....T....E....N....L....V.FS....LQKGIAEGEIK..P..DVDPLSIASELIGMMD.G.LQM.L.------------wlrapgeidmv..............
A0A1H8XRT5_9SPHI/112-185             ........................tavdaddtnpllkdkaaqavl-------------.-...-----..---------..---..--...--..-.---.....-...---.-....-.-....R.....W....K....K....S....I....E.NL....IQAGIDAGEFK..P..DADLSGTALSMIALIE.GgIMI.A.KV----------tntptsld.................
A0A0L0WC38_GOTPU/86-187              .............................................QLTNWVESQQRNI.E...TINES..LLICKTEFF..LTT..YYl.gNR..G.NHS.....Y...VTE.R....Y.Q....K.....L....V....N....S....I....K.KF....IQKGSERGEFQ..P..RLSSESIALYLISFLD.G.LML.D.TFHLGIERTKV-n........................
YFIR_BACSU/87-186                    ............................................s-ISSYLDELTEGL.R...DVADT..LAPVQFEYL..VTA..WR...NE..E.RRQ.....Y...LEK.R....Y.D....L.....F....V....E....R....F....S.RL....LQKGIDQGEFQ..P..VQPLATIAKFFLNMND.G.IIQ.N.ALYFDEEKADVS.........................
#=GR YFIR_BACSU/87-186         SS    ............................................H-HHHHHHCHHHHT.T...TGGGS..SHHHHHHHH..HGG..GG...-H..H.HHH.....H...HHH.H....H.H....H.....H....H....H....H....H....H.HH....HHHHHHTTS--..-..SS-HHHHHHHHHHHHH.H.HHH.H.HHHS-HHHH-HH.........................
#=GC SS_cons                         ............................................H-HHHHHHCHHHHT.T...TGGGS..SHHHHHHHH..HGG..GG...-H..H.HHH.....H...HHH.H....H.H....H.....H....H....H....H....H....H.HH....HHHHHHTTS--..-..SS-HHHHHHHHHHHHH.H.HHH.H.HHHS-HHHH-HH.........................
#=GC seq_cons                        ............................................h............h.....t.tps..lhhshhEaa..h.t...p...pt..p.tpp.....h...lpp.p....a.p....p.....t....h....p....h....l....p.pl....lppGlcpGEFp..s..phshpslAphlhshl-.G.lhl.p.shhht.......t........................
//
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