GenomeNet

Database: Pfam
Entry: TipAS
LinkDB: TipAS
Original site: TipAS 
#=GF ID   TipAS
#=GF AC   PF07739.15
#=GF DE   TipAS antibiotic-recognition domain
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   Pfam-B_8785 (release 14.0)
#=GF GA   23.80 23.80;
#=GF TC   23.80 23.80;
#=GF NC   23.70 23.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   12682015
#=GF RT   Structural basis for antibiotic recognition by the TipA class of
#=GF RT   multidrug-resistance transcriptional regulators. 
#=GF RA   Kahmann JD, Sass HJ, Allan MG, Seto H, Thompson CJ, Grzesiek S; 
#=GF RL   EMBO J 2003;22:1824-1834.
#=GF DR   INTERPRO; IPR012925;
#=GF DR   SCOP; 1ny9; fa;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain is found at the C-terminus of some MerR family
#=GF CC   transcription factors. The domain has an alpha-helical 
#=GF CC   globin-like fold [1]. The family includes Mta a central
#=GF CC   regulator of multidrug resistance in Bacillus subtilis.
#=GF SQ   3034
#=GS A0A4V2JHL3_STRKA/132-251  AC A0A4V2JHL3.1
#=GS A0A177L3Q5_9BACI/128-242  AC A0A177L3Q5.1
#=GS A0A383S4V6_9ACTN/138-252  AC A0A383S4V6.1
#=GS Q186Z8_CLOD6/159-290      AC Q186Z8.1
#=GS A0A1Y3Y042_9FIRM/166-278  AC A0A1Y3Y042.1
#=GS A0A1L8ZG88_9BACI/125-245  AC A0A1L8ZG88.1
#=GS A0A0Q3WRV4_9BACI/135-249  AC A0A0Q3WRV4.1
#=GS R4KGI2_CLOPA/159-289      AC R4KGI2.1
#=GS A0A5C8UPU4_9MICO/127-242  AC A0A5C8UPU4.1
#=GS A0A1H7UCQ2_9FIRM/124-239  AC A0A1H7UCQ2.1
#=GS A0A3A9AP91_9BACT/124-237  AC A0A3A9AP91.1
#=GS A0A239UAS9_9STAP/135-254  AC A0A239UAS9.1
#=GS A0A367Y2I1_9MICO/137-256  AC A0A367Y2I1.1
#=GS A0A2T6E309_9GAMM/129-245  AC A0A2T6E309.1
#=GS A0A367HQB6_9ACTN/132-251  AC A0A367HQB6.1
#=GS A0A285LQI9_9NOCA/134-251  AC A0A285LQI9.1
#=GS A4VTA8_STRSY/124-197      AC A4VTA8.1
#=GS A0A1E7JVP8_9ACTN/131-247  AC A0A1E7JVP8.1
#=GS A0A059W5G1_STRA9/143-259  AC A0A059W5G1.1
#=GS A0A1I0R794_9FIRM/124-239  AC A0A1I0R794.1
#=GS C6XSR3_PEDHD/138-256      AC C6XSR3.1
#=GS U2EFS0_9FIRM/131-249      AC U2EFS0.1
#=GS A0A0Q7DIM0_9RHIZ/132-251  AC A0A0Q7DIM0.1
#=GS A9WPQ7_RENSM/1-91         AC A9WPQ7.1
#=GS A0A1G5C9N3_9ACTN/198-301  AC A0A1G5C9N3.1
#=GS C0BZ04_9FIRM/127-285      AC C0BZ04.1
#=GS F9Q2C0_STROR/129-240      AC F9Q2C0.1
#=GS F4F6F6_VERMA/131-247      AC F4F6F6.1
#=GS A0A399UU40_9ACTN/139-254  AC A0A399UU40.1
#=GS A0A6I6S8R3_9ACTN/135-252  AC A0A6I6S8R3.1
#=GS A0A561Q5V9_9BACL/135-249  AC A0A561Q5V9.1
#=GS A0A095WPX6_9ACTO/135-250  AC A0A095WPX6.1
#=GS K6D8K5_BACAZ/135-249      AC K6D8K5.1
#=GS A0A1E7N4Z4_KITAU/136-247  AC A0A1E7N4Z4.1
#=GS A0A0D6W9D8_9ACTN/131-247  AC A0A0D6W9D8.1
#=GS A0A1G8SZX4_9ACTN/134-249  AC A0A1G8SZX4.1
#=GS A0A1A0TGL9_9MYCO/129-247  AC A0A1A0TGL9.1
#=GS A0A3M2KQZ4_9NOCA/133-247  AC A0A3M2KQZ4.1
#=GS A0A223KN00_9BACI/135-249  AC A0A223KN00.1
#=GS A0A3A4ALT2_9ACTN/168-304  AC A0A3A4ALT2.1
#=GS K6TWB6_9CLOT/135-249      AC K6TWB6.1
#=GS A0A268I9M3_9BACI/135-249  AC A0A268I9M3.1
#=GS A0A4V2F4L3_9ACTN/124-241  AC A0A4V2F4L3.1
#=GS A0A0W0YVM6_9GAMM/127-247  AC A0A0W0YVM6.1
#=GS A0A1S9CEY6_9FIRM/20-136   AC A0A1S9CEY6.1
#=GS A0A2H1K5A7_9MICO/117-237  AC A0A2H1K5A7.1
#=GS W7ZGM7_9BACI/135-249      AC W7ZGM7.1
#=GS A0A1X4IBC1_9ACTN/132-251  AC A0A1X4IBC1.1
#=GS B9E9R5_MACCJ/133-248      AC B9E9R5.1
#=GS A0A0A0JRC1_9MICO/137-253  AC A0A0A0JRC1.1
#=GS R4KGI2_CLOPA/290-380      AC R4KGI2.1
#=GS G2FP82_9FIRM/140-244      AC G2FP82.1
#=GS A0A410DTP0_9CLOT/159-292  AC A0A410DTP0.1
#=GS A0A562VDH7_9ACTN/163-277  AC A0A562VDH7.1
#=GS A0A0U4GRT3_9MICO/130-254  AC A0A0U4GRT3.1
#=GS A0A1I3PU67_9BACL/135-249  AC A0A1I3PU67.1
#=GS A0A1I2PZW5_9CLOT/135-251  AC A0A1I2PZW5.1
#=GS C8NID0_9LACT/129-240      AC C8NID0.1
#=GS A0A1C4V1F7_MICEC/131-247  AC A0A1C4V1F7.1
#=GS A0A1H0D4H3_9BACI/130-243  AC A0A1H0D4H3.1
#=GS A0A1C7GEC4_9FIRM/131-250  AC A0A1C7GEC4.1
#=GS A3DJE0_HUNT2/50-164       AC A3DJE0.1
#=GS A0A543AXW0_9ACTN/128-248  AC A0A543AXW0.1
#=GS A0A1G6NDW9_9ACTN/124-241  AC A0A1G6NDW9.1
#=GS A0A4R4MXA6_9ACTN/27-124   AC A0A4R4MXA6.1
#=GS A0A6G2UJN1_9ACTN/136-247  AC A0A6G2UJN1.1
#=GS A0A1C4SJN2_9ACTN/131-247  AC A0A1C4SJN2.1
#=GS A0A1U7EEF8_9LACT/128-236  AC A0A1U7EEF8.1
#=GS A0A1M6R5K1_9CLOT/159-290  AC A0A1M6R5K1.1
#=GS A0A059WAJ3_STRA9/181-296  AC A0A059WAJ3.1
#=GS A0A1F1JTA0_9MICO/155-271  AC A0A1F1JTA0.1
#=GS C8NHQ8_9LACT/127-238      AC C8NHQ8.1
#=GS A0A4T9T620_9ACTN/135-251  AC A0A4T9T620.1
#=GS D9R5M6_CLOSW/135-249      AC D9R5M6.1
#=GS A0A1I4XSB5_9CLOT/135-249  AC A0A1I4XSB5.1
#=GS A0A0B8N3U4_9NOCA/129-246  AC A0A0B8N3U4.1
#=GS A0A2I0SGM1_9ACTN/132-246  AC A0A2I0SGM1.1
#=GS A0A4R7AYT8_9NEIS/241-340  AC A0A4R7AYT8.1
#=GS A0A3R9UE61_9BACI/135-249  AC A0A3R9UE61.1
#=GS A0A177L4B0_9BACI/135-249  AC A0A177L4B0.1
#=GS A0A5J5G9V9_9BACL/135-249  AC A0A5J5G9V9.1
#=GS A0A0F7N7L0_9ACTN/130-247  AC A0A0F7N7L0.1
#=GS A0A1H0PB33_9PSEU/131-245  AC A0A1H0PB33.1
#=GS R7MMV2_9FIRM/129-245      AC R7MMV2.1
#=GS D9TC79_MICAI/131-247      AC D9TC79.1
#=GS A0A286GXC5_9ACTN/129-245  AC A0A286GXC5.1
#=GS A0A0J6XE80_9ACTN/10-123   AC A0A0J6XE80.1
#=GS A0A1N7ISJ1_9BACL/135-249  AC A0A1N7ISJ1.1
#=GS A0A0F4K6K9_9ACTN/134-247  AC A0A0F4K6K9.1
#=GS A0A329KK72_9BACL/129-241  AC A0A329KK72.1
#=GS A0A4Q7N1P3_9BACT/132-249  AC A0A4Q7N1P3.1
#=GS A1UNC4_MYCSK/133-247      AC A1UNC4.1
#=GS A0A2M8TBG5_9CLOT/159-303  AC A0A2M8TBG5.1
#=GS U2XQ50_9MICO/137-251      AC U2XQ50.1
#=GS A0A1I0Y0L9_9BACI/128-240  AC A0A1I0Y0L9.1
#=GS A0A1Y4TKH3_9FIRM/135-250  AC A0A1Y4TKH3.1
#=GS A0A6B2U307_9ACTN/140-254  AC A0A6B2U307.1
#=GS A0A285M130_9NOCA/135-250  AC A0A285M130.1
#=GS A0A1C5H364_9ACTN/131-247  AC A0A1C5H364.1
#=GS A0A2L0NFE4_9ACTN/133-247  AC A0A2L0NFE4.1
#=GS A0A1S2K8P5_9ACTN/131-247  AC A0A1S2K8P5.1
#=GS D4K3E3_9FIRM/124-239      AC D4K3E3.1
#=GS A0A263D375_9PSEU/131-245  AC A0A263D375.1
#=GS A0A4P7SQ25_9MICC/127-251  AC A0A4P7SQ25.1
#=GS A0A2U1ZUL8_9MICO/145-260  AC A0A2U1ZUL8.1
#=GS A0A2W2D2Z5_9ACTN/131-247  AC A0A2W2D2Z5.1
#=GS A0A150HGW6_9MICO/134-248  AC A0A150HGW6.1
#=GS A0A161I2D3_9MICO/127-247  AC A0A161I2D3.1
#=GS A0A370GTC3_9NOCA/127-242  AC A0A370GTC3.1
#=GS A0A2X0U218_9ACTO/140-254  AC A0A2X0U218.1
#=GS A0A1Y4SMP9_9FIRM/137-248  AC A0A1Y4SMP9.1
#=GS A0A4S2TSZ9_9ACTN/136-248  AC A0A4S2TSZ9.1
#=GS H5XSQ1_9FIRM/124-244      AC H5XSQ1.1
#=GS A0A4V2QCP8_9FIRM/131-285  AC A0A4V2QCP8.1
#=GS A0A4Q7KFP0_9PSEU/123-228  AC A0A4Q7KFP0.1
#=GS A0A328VDP9_9CHLR/131-247  AC A0A328VDP9.1
#=GS A0A3N6FZX1_9ACTN/127-241  AC A0A3N6FZX1.1
#=GS A0A3N1HR16_9ACTN/129-246  AC A0A3N1HR16.1
#=GS A0A366ZDA0_9ACTN/129-245  AC A0A366ZDA0.1
#=GS A0A142X773_9BACT/131-248  AC A0A142X773.1
#=GS A0A0N0I5N4_9BACI/131-245  AC A0A0N0I5N4.1
#=GS C6PMI4_9CLOT/159-303      AC C6PMI4.1
#=GS A0A380KXE5_9STRE/125-243  AC A0A380KXE5.1
#=GS A0A1Z2L2T2_9ACTN/136-248  AC A0A1Z2L2T2.1
#=GS D5E445_BACMQ/134-248      AC D5E445.1
#=GS K0F008_9NOCA/134-248      AC K0F008.1
#=GS A0A398CSJ0_9BACT/135-249  AC A0A398CSJ0.1
#=GS H6NBG0_9BACL/131-248      AC H6NBG0.1
#=GS A0A495IJR3_9MICO/127-244  AC A0A495IJR3.1
#=GS A0A5Q3QM14_9PSEU/127-241  AC A0A5Q3QM14.1
#=GS A0A089LT27_9BACL/138-252  AC A0A089LT27.1
#=GS A0A1H2YF41_9PSEU/129-245  AC A0A1H2YF41.1
#=GS A0A2U1K6B1_9BACI/130-244  AC A0A2U1K6B1.1
#=GS A0A1I1R2D0_9ACTN/135-251  AC A0A1I1R2D0.1
#=GS A0A285EL04_9ACTN/129-245  AC A0A285EL04.1
#=GS A0A1H8SMK8_9PSEU/132-248  AC A0A1H8SMK8.1
#=GS A0A069DHI1_9BACL/135-249  AC A0A069DHI1.1
#=GS H6RL86_BLASD/129-245      AC H6RL86.1
#=GS A0A1H8FKN9_9BURK/130-247  AC A0A1H8FKN9.1
#=GS A0A248YJW6_9ACTN/131-247  AC A0A248YJW6.1
#=GS Q24YF4_DESHY/128-242      AC Q24YF4.1
#=GS A0A0N9I3J4_9PSEU/139-253  AC A0A0N9I3J4.1
#=GS A0A5C4VCT6_9ACTN/138-252  AC A0A5C4VCT6.1
#=GS A0A3N0AY78_9ACTN/133-250  AC A0A3N0AY78.1
#=GS A0A136Q5H8_9FIRM/136-250  AC A0A136Q5H8.1
#=GS A0A3A8WM75_9BACT/159-281  AC A0A3A8WM75.1
#=GS A0A429UET7_9ACTN/135-248  AC A0A429UET7.1
#=GS A0A2R4T468_9ACTN/127-241  AC A0A2R4T468.1
#=GS A0A3D8GNV0_9BACI/135-249  AC A0A3D8GNV0.1
#=GS R6WRY4_9FIRM/14-129       AC R6WRY4.1
#=GS A0A417N2J5_9FIRM/124-235  AC A0A417N2J5.1
#=GS A0A1E8FVT3_9MICC/132-246  AC A0A1E8FVT3.1
#=GS A0A2B8ANK1_9ACTN/127-243  AC A0A2B8ANK1.1
#=GS M2P9S4_9FIRM/143-252      AC M2P9S4.1
#=GS C5R9M2_WEIPA/135-249      AC C5R9M2.1
#=GS A0A1I4JVA0_9BACI/128-237  AC A0A1I4JVA0.1
#=GS A0A2N0Z225_9BACI/135-249  AC A0A2N0Z225.1
#=GS A0A0B0I4M1_9BACL/128-231  AC A0A0B0I4M1.1
#=GS U2EFP2_9FIRM/293-382      AC U2EFP2.1
#=GS A0A0E3W3N6_9FIRM/135-249  AC A0A0E3W3N6.1
#=GS A0A2W2EK63_9ACTN/134-240  AC A0A2W2EK63.1
#=GS A0A3P1VD85_9STRE/125-239  AC A0A3P1VD85.1
#=GS A0A1L8WNN2_9ENTE/1-92     AC A0A1L8WNN2.1
#=GS A0A4S2V3M5_9ACTN/132-251  AC A0A4S2V3M5.1
#=GS A0A037Z2U6_CLOTT/159-290  AC A0A037Z2U6.1
#=GS A0A2N3UMD0_9ACTN/136-252  AC A0A2N3UMD0.1
#=GS A5N5M3_CLOK5/306-396      AC A5N5M3.1
#=GS A0A6I1GD70_9MICO/139-255  AC A0A6I1GD70.1
#=GS A0A0B0HHU2_9BACI/1-73     AC A0A0B0HHU2.1
#=GS A0A4R6BT97_9STAP/128-242  AC A0A4R6BT97.1
#=GS C0ZE86_BREBN/124-242      AC C0ZE86.1
#=GS A0A498D7I3_9BACI/128-240  AC A0A498D7I3.1
#=GS A0A3G3K335_9BACL/135-249  AC A0A3G3K335.1
#=GS A0A3T1D7V5_9BACL/135-249  AC A0A3T1D7V5.1
#=GS D9QEM6_CORP2/131-245      AC D9QEM6.1
#=GS A0A0A8B5B4_9ACTN/129-240  AC A0A0A8B5B4.1
#=GS A0A2P7PY01_9ACTN/132-251  AC A0A2P7PY01.1
#=GS A0A560WEH1_9MICO/133-248  AC A0A560WEH1.1
#=GS A0A3M8EW05_9ACTN/127-242  AC A0A3M8EW05.1
#=GS E8U4S1_DEIML/131-247      AC E8U4S1.1
#=GS A0A075JJN7_9BACI/130-242  AC A0A075JJN7.1
#=GS A0A161WJK8_9CLOT/159-291  AC A0A161WJK8.1
#=GS A0A1H6EUC0_9ACTN/131-247  AC A0A1H6EUC0.1
#=GS V6K0L9_STRNV/1-66         AC V6K0L9.1
#=GS A4FQS4_SACEN/129-245      AC A4FQS4.1
#=GS A0A2V1KAJ1_9ACTO/139-254  AC A0A2V1KAJ1.1
#=GS A0A0N0H2F0_9ACTN/136-249  AC A0A0N0H2F0.1
#=GS A0A1H7TAI5_9ACTN/130-246  AC A0A1H7TAI5.1
#=GS A0A0J8VW15_9ENTR/125-231  AC A0A0J8VW15.1
#=GS A8MEK2_ALKOO/101-242      AC A8MEK2.1
#=GS A0A1E8GQ76_9LACT/128-243  AC A0A1E8GQ76.1
#=GS A0A1H2QP04_9BACL/135-249  AC A0A1H2QP04.1
#=GS A0A2K2UED9_9ACTN/141-257  AC A0A2K2UED9.1
#=GS R7WMU5_9NOCA/130-250      AC R7WMU5.1
#=GS A0A1I4MHW1_9BURK/8-122    AC A0A1I4MHW1.1
#=GS A0A0P6WRW7_9BACI/135-249  AC A0A0P6WRW7.1
#=GS U2TEJ5_9ACTN/129-240      AC U2TEJ5.1
#=GS B7C972_9FIRM/126-241      AC B7C972.1
#=GS A0A516KKZ1_9BACI/135-249  AC A0A516KKZ1.1
#=GS V6IW51_9BACL/135-250      AC V6IW51.1
#=GS W4QNI3_BACA3/128-237      AC W4QNI3.1
#=GS A0A1I0AL66_9BACL/148-245  AC A0A1I0AL66.1
#=GS A0A1M7HTY5_9FIRM/126-240  AC A0A1M7HTY5.1
#=GS A0A396L673_9FIRM/166-278  AC A0A396L673.1
#=GS A0A0V8QAF8_9FIRM/135-250  AC A0A0V8QAF8.1
#=GS A0A1M6B6R0_9FIRM/135-249  AC A0A1M6B6R0.1
#=GS A0A3A9C9A0_9BACT/1-80     AC A0A3A9C9A0.1
#=GS A0A0F0HJD5_9PSEU/134-247  AC A0A0F0HJD5.1
#=GS A0A1Q5LLJ3_9ACTN/131-247  AC A0A1Q5LLJ3.1
#=GS A0A430AJL3_9ENTE/128-248  AC A0A430AJL3.1
#=GS A0A0M8Y3H8_9ACTN/127-241  AC A0A0M8Y3H8.1
#=GS A0A0Q8CTQ0_9MICO/127-247  AC A0A0Q8CTQ0.1
#=GS F6FRP8_ISOV2/127-247      AC F6FRP8.1
#=GS A0A0F0LYZ5_9MICO/126-245  AC A0A0F0LYZ5.1
#=GS A0A4R4WP11_9ACTN/81-198   AC A0A4R4WP11.1
#=GS A0A2S9Z5J2_9CORY/146-251  AC A0A2S9Z5J2.1
#=GS A0A1G6JYW9_9BURK/10-122   AC A0A1G6JYW9.1
#=GS K9R6W7_9CYAN/127-232      AC K9R6W7.1
#=GS A0A1H5L920_9MICO/131-252  AC A0A1H5L920.1
#=GS A0A1K1QUP0_9BACL/126-245  AC A0A1K1QUP0.1
#=GS N9Y3S5_9CLOT/135-250      AC N9Y3S5.1
#=GS G9WIL8_9LACT/134-249      AC G9WIL8.1
#=GS A0A4Z0C7K0_9BURK/140-230  AC A0A4Z0C7K0.1
#=GS A0A5M3W109_9ACTN/3-47     AC A0A5M3W109.1
#=GS L8TTR3_9MICC/117-237      AC L8TTR3.1
#=GS A0A561BY11_9ACTN/137-249  AC A0A561BY11.1
#=GS A0A2L0N4P1_9ACTN/133-249  AC A0A2L0N4P1.1
#=GS SKGA_CAUVC/132-251        AC P0CAV4.1
#=GS A0A4S4BME4_9BACI/135-249  AC A0A4S4BME4.1
#=GS A0A5Q0HDE6_9PSEU/141-255  AC A0A5Q0HDE6.1
#=GS A0A268IBL9_9BACI/139-249  AC A0A268IBL9.1
#=GS A0A2G8SVS4_9BURK/10-122   AC A0A2G8SVS4.1
#=GS A0A1I6WGM9_9BACL/135-249  AC A0A1I6WGM9.1
#=GS A0A2R7JVV2_9SPHN/135-249  AC A0A2R7JVV2.1
#=GS A0A061AA43_9MOLU/136-249  AC A0A061AA43.1
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