#=GF ID   Tnp_IS30_N
#=GF AC   PF30461.1
#=GF DE   IS30 family transposase, N-terminal domain
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   TED:P0CF88_TED01
#=GF GA   27.00 27.00;
#=GF TC   27.20 27.40;
#=GF NC   26.90 26.90;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 90746521 --cpu 8 -E 1000 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0123
#=GF RN   [1]
#=GF RM   6092059
#=GF RT   Nucleotide sequence of the prokaryotic mobile genetic element
#=GF RT   IS30.
#=GF RA   Dalrymple B., Caspers P., Arber W.;
#=GF RL   EMBO J. 1984;3:2145-2149.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This entry represents the N-terminal domain of IS30 family
#=GF CC   transposases. It precedes the HTH DNA-binding domain
#=GF CC   (Pfam:PF13936) and the C-terminal integrase catalytic domain
#=GF CC   (Pfam:PF00665). IS30 is a bacterial insertion sequence element
#=GF CC   first characterised in Escherichia coli [1]. The transposase is
#=GF CC   required for mobilisation of the insertion element. Multiple
#=GF CC   copies of IS30 elements are present in E. coli K12, designated
#=GF CC   IS30A, IS30C and IS30D. The family is found in Pseudomonadota
#=GF CC   and Actinomycetota, including Escherichia and Streptomyces. The
#=GF CC   specific function of this N-terminal domain remains to be
#=GF CC   determined.
#=GF SQ   52
#=GS A0AB38RN35_RHOSG/10-46  AC A0AB38RN35.1
#=GS A0A550H9W7_9ACTN/10-46  AC A0A550H9W7.1
#=GS H8MG73_CORCM/9-45       AC H8MG73.1
#=GS A0A1H8G6W3_STIAU/9-45   AC A0A1H8G6W3.1
#=GS A0A2C6DJQ8_9GAMM/6-42   AC A0A2C6DJQ8.1
#=GS B7LEP8_ECO55/6-42       AC B7LEP8.1
#=GS A0A846Y9W9_9NOCA/10-46  AC A0A846Y9W9.1
#=GS A0A1Y2MHJ0_PSEAH/18-54  AC A0A1Y2MHJ0.1
#=GS A0A2M9LVW1_9ACTN/10-46  AC A0A2M9LVW1.1
#=GS A0A2H5AVC1_9ACTN/10-46  AC A0A2H5AVC1.1
#=GS A0A1C4K6Y3_9ACTN/10-46  AC A0A1C4K6Y3.1
#=GS A0A0M4R878_9PSEU/2-38   AC A0A0M4R878.1
#=GS A0A944JBR8_9ACTN/2-34   AC A0A944JBR8.1
#=GS INSI4_ECOLI/6-42        AC P0CF90.1
#=GS A0A4U1B7D8_9GAMM/6-42   AC A0A4U1B7D8.1
#=GS A0A1M7QZI7_9ACTN/10-46  AC A0A1M7QZI7.1
#=GS A0A3Q8WS53_9ACTO/1-27   AC A0A3Q8WS53.1
#=GS A0A0M4Q3Z1_9PSEU/10-46  AC A0A0M4Q3Z1.1
#=GS A0A5N8VAZ7_9ACTN/10-46  AC A0A5N8VAZ7.1
#=GS A0A6N7L1N3_9ACTN/10-46  AC A0A6N7L1N3.1
#=GS A0A7W7RZM6_9ACTN/2-34   AC A0A7W7RZM6.1
#=GS A0A918YSR4_9ACTN/2-38   AC A0A918YSR4.1
#=GS A0A4Q0Y7J0_9GAMM/9-45   AC A0A4Q0Y7J0.1
#=GS A0A486XSQ5_9BACT/11-47  AC A0A486XSQ5.1
#=GS A0A1M7Q7T4_9ACTN/10-46  AC A0A1M7Q7T4.1
#=GS A0A2T0LJ04_9ACTN/1-34   AC A0A2T0LJ04.1
#=GS A0A6N7KXH0_9ACTN/10-46  AC A0A6N7KXH0.1
#=GS Q8X986_ECO57/6-42       AC Q8X986.1
#=GS B7UTG1_ECO27/6-42       AC B7UTG1.1
#=GS A0A7S9DV79_9ALTE/9-45   AC A0A7S9DV79.1
#=GS A0A0X3V1G6_9ACTN/10-46  AC A0A0X3V1G6.1
#=GS A0AA37WL65_9ALTE/9-45   AC A0AA37WL65.1
#=GS A7ZGM0_ECO24/6-42       AC A7ZGM0.1
#=GS A0A1B1ZJ52_9PSEU/18-54  AC A0A1B1ZJ52.1
#=GS A0A0H2VCF2_ECOL6/6-42   AC A0A0H2VCF2.1
#=GS INSI3_ECOLI/6-42        AC P0CF89.1
#=GS B7MLS4_ECO45/6-42       AC B7MLS4.1
#=GS B7L8Y0_ECO55/6-42       AC B7L8Y0.1
#=GS A0A328TKU8_9GAMM/6-42   AC A0A328TKU8.1
#=GS A0A328TLN7_9GAMM/6-42   AC A0A328TLN7.1
#=GS A4FCT3_SACEN/10-46      AC A4FCT3.1
#=GS A0A486XST7_9BACT/11-47  AC A0A486XST7.1
#=GS M1UHY3_9CORY/10-46      AC M1UHY3.1
#=GS A0A3S8Z7S6_9ACTO/1-27   AC A0A3S8Z7S6.1
#=GS A0A4R3J5T2_9PROT/8-44   AC A0A4R3J5T2.1
#=GS A0AA37WK59_9ALTE/9-45   AC A0AA37WK59.1
#=GS A0A1Q5FXW9_9ACTN/10-46  AC A0A1Q5FXW9.1
#=GS INSI1_ECOLI/6-42        AC P0CF88.1
#=GS A0A250B673_9GAMM/6-42   AC A0A250B673.1
#=GS A0A5J5G1V4_9GAMM/6-42   AC A0A5J5G1V4.1
#=GS W5W9X9_9PSEU/10-46      AC W5W9X9.1
#=GS A0A0W0XTB9_9GAMM/11-47  AC A0A0W0XTB9.1
A0AB38RN35_RHOSG/10-46             ....s-DEKKAELWRRWRAGESISVISRALRKPPGSVFTVLK..
A0A550H9W7_9ACTN/10-46             .sdem----KADLWRRWRAGESISVISRQIGKPPGSVFTVLK..
H8MG73_CORCM/9-45                  .....SAEQRAEIWKRWKAGQSMSDISRAVGRMPGTVHGVL-s.
A0A1H8G6W3_STIAU/9-45              .....SADQRAEIWRRWKAGQSLSEISRALGRVPGTVHNVL-s.
A0A2C6DJQ8_9GAMM/6-42              .....TTKEKAFVFDLWKSGTGFSEIAKILDSKPGTIFTMLR..
B7LEP8_ECO55/6-42                  .....TAEEKASVFELWKNGTGFSEIANILGSKPGTIFTMLR..
A0A846Y9W9_9NOCA/10-46             seamk-----TELWRRWRAGESISVISRALDKPPGSVFTVLK..
A0A1Y2MHJ0_PSEAH/18-54             .....SDEDRQQLWDRWARGESISQIARAILRPPGSVFTVLK..
A0A2M9LVW1_9ACTN/10-46             .sdem----KADLWRRWRAGESISVISRQIGKPPGSVFTVLK..
A0A2H5AVC1_9ACTN/10-46             ....s-DAQKRELWDRWKAGESISEISRALGRPPGSIFTIVK..
A0A1C4K6Y3_9ACTN/10-46             .sdem----KADLWRRWGAGESISVISRQIGKPPGSVFTVL-e.
A0A0M4R878_9PSEU/2-38              ..sda---DRADLWVRWGRGESISDIARAIGRPPGSVFTVLK..
A0A944JBR8_9ACTN/2-34              ..kad-------LWRRWRAGESISVISRQIGKPPGSVFTVLK..
INSI4_ECOLI/6-42                   .....TAEEKASVFELWKNGTGFSEIANILGSKPGTIFTMLR..
A0A4U1B7D8_9GAMM/6-42              .....SEQEREFVFDSWKRGVGFSEIAQQLDTKPGTVFTMLR..
A0A1M7QZI7_9ACTN/10-46             .sdem----KADLWRRWRAGESISVISRQIGKPPGSVFTVLK..
A0A3Q8WS53_9ACTO/1-27              .....----------MWKTGASISEIGRTVGSPPGSIFSILL..
A0A0M4Q3Z1_9PSEU/10-46             ..sda---DRADLWVRWGRGESISDIARAIGRPPGSVFTVLK..
A0A5N8VAZ7_9ACTN/10-46             .sdem----KADLWRRWRAGESISVISRQIGKPPGSVFTVLK..
A0A6N7L1N3_9ACTN/10-46             ....s-DTQKRELWDRWKAGESISEISRALGRPPGSIFTIIK..
A0A7W7RZM6_9ACTN/2-34              .kvdl--------WRQWRAGDSISMISRTLGKPPGSVFTVLK..
A0A918YSR4_9ACTN/2-38              .sdem----KADLWRRWRAGESISVISRQIGKPPGSVFTVLK..
A0A4Q0Y7J0_9GAMM/9-45              .....SQDEKNFIFDLWKQGVGFSDIGKLLAAAPGTVFTVLR..
A0A486XSQ5_9BACT/11-47             .....TEEQQNTMWNLWSKGKSHSEIGRQLNKRAGSVFCFL-q.
A0A1M7Q7T4_9ACTN/10-46             ....s-DTQKRELWDRWKAGESISGISRALGRPPGSIFTIVK..
A0A2T0LJ04_9ACTN/1-34              ....m----KEDLWRRWRAGESISVISRGLGKPPGSVFTVLK..
A0A6N7KXH0_9ACTN/10-46             ....s-DTQKRELWDRWKAGESISEISRALGRPPGSIFTIIK..
Q8X986_ECO57/6-42                  .....TAEEKASVFELWKNGTGFSEIANILGSKPGTIFTMLR..
B7UTG1_ECO27/6-42                  .....TAEEKASVFELWKNGTGFSEIANILGSKPGTIFTMLR..
A0A7S9DV79_9ALTE/9-45              .....TPEERALVFDLWKQGAGFSEIGRVVAAKPGSVFTILR..
A0A0X3V1G6_9ACTN/10-46             .sdam----KEDLWRRWRCGDSISVIGRALGKPPGSVFTVLK..
A0AA37WL65_9ALTE/9-45              .....TQDERELVFDLWKQGAGFSDIGRVIEAKPGSVFTILK..
A7ZGM0_ECO24/6-42                  .....TAEEKASVFELWKNGTGFSEIANILGSKPGTIFTMLR..
A0A1B1ZJ52_9PSEU/18-54             .sdgd----RRELWVRWGRGESISEIGRAIARPPGSVFTVLK..
A0A0H2VCF2_ECOL6/6-42              .....TAEEKASVFELWKNGTGFSEIANILGSKPGTIFTMLR..
INSI3_ECOLI/6-42                   .....TAEEKASVFELWKNGTGFSEIANILGSKPGTIFTMLR..
B7MLS4_ECO45/6-42                  .....TAEEKASVFELWKNGTGFSEIANILGSKPGTIFTMLR..
B7L8Y0_ECO55/6-42                  .....TAEEKASVFELWKNGTGFSEIANILGSKPGTIFTMLR..
A0A328TKU8_9GAMM/6-42              .....TAKEKASVFELWKNGTDFSEIANILGSKPGTIFTMLR..
A0A328TLN7_9GAMM/6-42              .....TAKEKSSVFELWKNGTSFSEIANILGSKLGTIFTMLR..
A4FCT3_SACEN/10-46                 ...sd--EMKEDLWRRWRAGESISVISREIGKPPGSVFTVLK..
A0A486XST7_9BACT/11-47             .....TEEQQNTMWNLWSKGKSHSEIGRQLNKRAGSVFCFL-q.
M1UHY3_9CORY/10-46                 .....PQDQRQKVWDLWKTGSSISDISRDVGSPPGSIFSILL..
A0A3S8Z7S6_9ACTO/1-27              .....----------MWKTGASISEIGRTVGSPPGSIFSILL..
A0A4R3J5T2_9PROT/8-44              ...nd--QKKAVIWDEWKNGIPMIQIARAIEKPPATIFSYLR..
A0AA37WK59_9ALTE/9-45              .....TQDERELVFDLWKQGAGFSDIGRVIEAKPGSVFTILK..
A0A1Q5FXW9_9ACTN/10-46             ....s-DAQKQEVWRRWKEGQSLSEIGRALGKVPGSIHGV--vk
INSI1_ECOLI/6-42                   .....TAEEKASVFELWKNGTGFSEIANILGSKPGTIFTMLR..
A0A250B673_9GAMM/6-42              .....TAKEKASVFELWKNGTGFSEIANILGSKPGTIFTMLR..
A0A5J5G1V4_9GAMM/6-42              .....TAMENEFVSDFWHNGIGYREMAKTPDSKPGTIVTIFR..
W5W9X9_9PSEU/10-46                 .sdem----KDELWRRWRAGESISDISRGIGKPPGSVFTVLK..
A0A0W0XTB9_9GAMM/11-47             .....TEHQQDVIWSLWSQGKSLSEIGRQLNKHAGSIFCFL-q.
#=GC seq_cons                      ......tppKsplachW+sGpShS-IuRtlGp.PGSlFTlL+..
//