GenomeNet

Database: Pfam
Entry: UL97
LinkDB: UL97
Original site: UL97 
#=GF ID   UL97
#=GF AC   PF06734.15
#=GF DE   UL97
#=GF AU   Vella Briffa B;0000-0003-4380-1783
#=GF SE   Pfam-B_1747 (release 10.0)
#=GF GA   25.00 25.00;
#=GF TC   32.30 31.40;
#=GF NC   24.90 22.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0016
#=GF RN   [1]
#=GF RM   9217058
#=GF RT   The murine cytomegalovirus (MCMV) homolog of the HCMV
#=GF RT   phosphotransferase (UL97(pk)) gene. 
#=GF RA   Rawlinson WD, Zeng F, Farrell HE, Cunningham AL, Scalzo AA,
#=GF RA   Booth TW, Scott GM; 
#=GF RL   Virology 1997;233:358-363.
#=GF DR   INTERPRO; IPR010615;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family represents a conserved region within viral UL97
#=GF CC   phosphotransferases. UL97 participates in the phosphorylation of
#=GF CC   the nucleoside analog ganciclovir (GCV) to produce
#=GF CC   GCV-monophosphate [1].
#=GF SQ   29
#=GS O71123_9BETA/363-545      AC O71123.1
#=GS G8XUG2_9BETA/337-518      AC G8XUG2.1
#=GS I3VQ90_9BETA/386-567      AC I3VQ90.1
#=GS GCVK_HHV7J/302-481        AC P52344.1
#=GS Q9DWA3_RCMVM/366-548      AC Q9DWA3.1
#=GS A0A0S1TR52_9BETA/304-462  AC A0A0S1TR52.1
#=GS GCVK_HHV6Z/319-498        AC P52446.2
#=GS Q772M9_RHCM6/363-545      AC Q772M9.1
#=GS A0A0K1GZL7_9BETA/361-543  AC A0A0K1GZL7.1
#=GS Q91TK7_TUHV1/416-597      AC Q91TK7.1
#=GS A0A1P8VIX5_9BETA/435-614  AC A0A1P8VIX5.1
#=GS H2A2C8_MUHV1/396-576      AC H2A2C8.1
#=GS A0A075CYI2_9BETA/282-456  AC A0A075CYI2.1
#=GS K7XR37_RCMVE/320-505      AC K7XR37.1
#=GS A0A191S3T6_9BETA/278-457  AC A0A191S3T6.1
#=GS A0A0F7CSV1_SCMVC/384-566  AC A0A0F7CSV1.1
#=GS GCVK_HHV6U/318-497        AC P24446.1
#=GS M1RVB3_ELHV1/279-407      AC M1RVB3.1
#=GS A0A1L6Z111_9BETA/361-543  AC A0A1L6Z111.1
#=GS Q67670_9BETA/356-537      AC Q67670.2
#=GS UL97_HCMVM/461-642        AC Q6SW46.1
#=GS G8XT01_9BETA/317-498      AC G8XT01.1
#=GS Q8QS03_9BETA/524-705      AC Q8QS03.1
#=GS M9TNH0_9BETA/318-497      AC M9TNH0.1
#=GS UL97_HCMVA/461-642        AC P16788.1
#=GS A0A0G2UGM1_SCMVC/352-534  AC A0A0G2UGM1.1
#=GS B3UX44_MUHV1/396-576      AC B3UX44.1
#=GS G8XTZ3_SCMVC/347-529      AC G8XTZ3.1
#=GS A8E1L5_MUHVK/396-576      AC A8E1L5.1
O71123_9BETA/363-545                 ..........NVLINVNPHYHSEILHVALCDYSLSEPYPV...CNDRCVVVFQETGTARRIPNCTHRL..RECYHPAFRPLPLQKLMIC.NPHARF.....PV.S.NsPRRFCMIELAALGNVLA.FCLVRLLDRRGIEGVHNGPESLLFKHAATACHALENNRLTACSDACLLIMAAQLSYHAGLLGDDGLA.VVSQTVGFVEAKMS......................................................
G8XUG2_9BETA/337-518                 ..........NVLIDVSPQKPGEIVRVALCDYSLCEMHPT...CGRRGAVVFQETQTARPLPACMHRL..RECYHPAFRPVPLQKLVTL.NPHARF.....PV.G.S.PQRFCAAEMVALANVLL.FCLARVLDRRGLEAVRRGPEHMLFQHAAVACRALDAGDVTACSGACLMILAAQLSYLSYLLGDVAAP.TICRLHRFVESR--fd....................................................
I3VQ90_9BETA/386-567                 ..........NIVIMINRGRPYDIDEAVLCDYSLSEPHPM...YNRKCVAVFQETKTARFIPDSVYRV..SECYHPAFRPLPLQRMVIL.NPERRF.....VS.E.S.ARAYCTAELCALGNVAM.FCMARVVNEKGLQHVRNTGENMLFQAASIACKALEQGSLESYATGCVYIMARQMAYAYSVLGYPASL.TAQRVMQDM-----edrca.................................................
GCVK_HHV7J/302-481                   ..........NILIH---HKEGIILEAVLADYSLAEVHPQ...YNGKCGILRQFDHRIQIVPKSYNKL..CDMFNPGFRPMIAHKIILV.EVYAEFdgkgnPV.-.-.--RHCNLDLCALAQVFL.LCVIRMLDERGCREAQKYYENRLFTYSNEACTLNPIKYPLEYKDACCKVLAEHLVLFGILFYREVVD.MFENLYDFLHASG-d.....................................................
Q9DWA3_RCMVM/366-548                 ..........NILVQVDPEDGRRLRRAVLCDYSLAQYNGP...HDDRCVVVFQQTRTVRALQSSTYYL..TDLYHPAFKPLPLQKLSCV.EPRARF.....PH.P.S.ARRFCVTDLCALGSVVA.FCLVRVLDDRGLPKVRATTENALFAVARKTCEALGRHDEDAVANWSSLLLTRQLAYAVSLLGVDEA-.--------------reavadlchffaanad......................................
A0A0S1TR52_9BETA/304-462             ..........NILIN---VDGEYIVSAVIGDYSLTSRHDR...H--RAIIVMN-ESTGKSLGICQQDLqvNCTYQIVYRPISLMFWCVT.MPDLSIw...rLC.R.N.SREFCVMDLCAMGRVVMlFCLNLIHYETGL-------------------------------------------------------.--------------sirkgmfdvnrkyenepsedrtrkteygihallnclwivtclcsdyh.......
GCVK_HHV6Z/319-498                   ..........NIFIN---HKKEIIFDAVLADYSLSEIHPE...YNGTCAIAKEYDRNLQLVPISRNKF..CDMFNPGFRPLVANAMILV.NVCEAFdgennPL.-.-.--RHCNLDLCAFAQVVL.LCVLRMTDKRGCREAQLYYEKRLFALANEACRLNPLRYPFAYRDACCKVLAEHVVLLGLLFYRDVVD.IYEKIYDFLDERGE......................................................
Q772M9_RHCM6/363-545                 ..........NVLINVNPHYHSEILHVALCDYSLSEPYPV...CNDRCVVVFQETGTARRIPNCTHRL..RECYHPAFRPLPLQKLMIC.NPHARF.....PV.S.NsPRRFCMIELAALGNVLA.FCLVRLLDRRGIEGVHNGPESLLFKHAATACHALENNRLTACSDACLLIMAAQLSYHAGLLGDDGLA.VVSQTVGFVEAKMS......................................................
A0A0K1GZL7_9BETA/361-543             ..........NVLINVNPHYHSEILHVVLCDYSLSEPYPV...CNDRCVVVFQETGTARRIPNCTHRL..RECYHPAFRPLPLQKLMIC.NPHARF.....PV.S.NsPRRFCMIELAALGNVLA.FCLVRLLDRRGIEAVHNGPESLLFKHAATACHALENNRLTACSDACLLIMAAQLSYHAGLLGDDGLT.VVSQTVSFVEAKMS......................................................
Q91TK7_TUHV1/416-597                 nilvvpsrtc----------PGVLEHAVLCDYSLSEPHSD...FNRRCVVVFEQTKTARVLEDSRQRI..CECYHPAFRPVPLQRIVVI.NPHATF.....PV.G.A.RNRYSVAELCALGNVAL.FCLARLLDERGEDFVRYSCENALFRVAGSACRAMEADDLRSYSDRCLRILAHQLAYIHAVLGDMASG.IVTRTQRYVQVQ--cd....................................................
A0A1P8VIX5_9BETA/435-614             ..........NIFIN---HDSGYIISGVLGDYSLAEVHPQ...YQSTSCIAIPRFKTLNRLSAQNNKI..CEMYNPTMRPIVIQKDVMV.NVNAEFngmgrPV.-.-.--RHCNLDLCALGNTVV.MMLFRLLCEGGIHAAKVLFDNKLFGVGNDACLYHPIYAPESYRASCCRIVAYQLLFNGIFFPRDLIE.NYEHVLDHLTE---skc...................................................
H2A2C8_MUHV1/396-576                 ..........NVLINYDRADDRQIARAVICDFSLSQCHTE..gTTGHCVVVFQQTKTVRALPKSAYYL..TDIYHPAFKPLMLQKLCAI.EPRKQF.....PK.P.S.ANRFCVSDLCALGHVAA.FCLVRVLDERGQLKVRSTSEDALFGVARKTCDALARHSVDEVANFCSLLITRQLAYTATLLGSDD--.--------------mrepmarlcdyfet........................................
A0A075CYI2_9BETA/282-456             ..........NILIN---TDEEYILHAVLGDYSLCSRH-D...RERAIIIMNENNGKSLGVCQSDLQV..DSTYQIIYRPLHLIFWCITmRTLSIW.....HL.CrA.SRDFCVMDLCALGRVAT.LFALNLISY----ETGMSVKKGLFSV-----------------------------------------.--------------hkkyekektsghkveygihvilnslwilsclcpnfykdagatmmeklidvfpqh
K7XR37_RCMVE/320-505                 ..........NFLINVNPSDDRHIERAVICDFSLSQYHGDggnKDGRCVVVFEETKTVRALTKSTFYL..TDIYHPAFKPLFLQKLCTI.RPRMQF.....PN.P.T.EKRLCVADLCALGNVVA.FCLVRVLDERGQFKVRLTSEDALFSTARKTCDALARHCIDDIANMCSLVIPRQLAYFATVLGSSELEgTVSRLCDFF-----atesd.................................................
A0A191S3T6_9BETA/278-457             ..........NILIQ---HNKGLILEAVLADYSLAEVHPE...YNEKCGILRQFDNRIQIVPKSYNKL..CDMYNPGFRPMVAHKIILA.DIYAEFegknnPV.-.-.--RHCNLDLCALSQVFL.LCVMRMLDERGCREAQKYYENRLFTYSNEACLINPIKDPLDYKDACCKVLAEHVVLFGILFYRDVVD.VFETFYDFLDANS-e.....................................................
A0A0F7CSV1_SCMVC/384-566             ..........NVLVNVNPHYPSEILHAVLCDYSLSEPYPV...CNDRCVVVFQETGTARRIPNCTHRV..RECYHPAFRPLPLQKLMIS.NPHARF.....PD.S.SlLRRFCMAELAALGNVLG.FCLVRLLDRRGIREVQGGPEAMLFKHASTACRALESNRLTACSDACMLIMAAQLAYHAGLLGDEGLP.IVNRTVNFVENKL-s.....................................................
GCVK_HHV6U/318-497                   ..........NIFLN---HKKEIIFDAVLADYSLSEMHPN...YNGTCAIAKEYDKNLQLVPISRNKF..CDMFNPGFRPLVANAMILV.NVCGAFdgennPL.-.-.--RHCNLDLCAFAQVVL.SCVLRMTDKRGCREAQLYYEKRLFALANEACRLNPLKYPFAYRDACCKVLAEHVVLLGLLFYRDVVE.IYEKLYDFLDERGE......................................................
M1RVB3_ELHV1/279-407                 ..........NILIN---TDEEYILHAVLGDYSLCSRH-D...RERAIIIMNENNGKSLGVCQSDLQV..EGTYQIVYRPLHLM--FWC.VTMRTLs..iwQL.CrE.AREFCVMDLCALGRVAT.LFTLHLISHE---------------------------------------------------------.--------------tsvsvrrglfsvhkkyekek..................................
A0A1L6Z111_9BETA/361-543             ..........NVLINVNPHYHSEILHVVLCDYSLSEPYPV...CNDRCVVVFQETGTARRIPNCTHRL..RECYHPAFRPLPLQKLMIC.NPHARF.....PV.S.NsPRRFCMIELAALGNVLA.FCLVRLLDRRGIEAVHNGPESLLFKHAATACHALENNRLTACSDACLLIMAAQLSYHAGLLGDDGLA.VVSQTVSFVEAKMS......................................................
Q67670_9BETA/356-537                 ..........NCLIKVDPSAPYRIARAALCDYSLTEPHPM...YNRRCAVVLQETKSVRMLPDSQYKL..CECYHPAFRPIILQRTVCA.EPDGYF.....PF.E.D.WGQFCVAEICALGMVVC.FCLMRTLDWRGVPTVRRVSESLLFQATPLACDAMEKQDLAGYSSACLAIMARQLAYVGAILGSRVSD.TFERTKRFVKV---qcg...................................................
UL97_HCMVM/461-642                   ..........NVLIDVNPHNPSEIVRAALCDYSLSEPYPD...YNERCVAVFQETGTARRIPNCSHRL..RECYHPAFRPMPLQKLLIC.DPHARF.....PV.A.G.LRRYCMSELSALGNVLG.FCLMRLLDRRGLDEVRMGTEALLFKHAGAACRALENGKLTHCSDACLLILAAQMSYGACLLGEHGAA.LVSHTLRFVEAKMS......................................................
G8XT01_9BETA/317-498                 ..........NVLIDVNPQKPSEIVRVALCDYSLCEPYPA...LNRRCAVIFQETQSARILPSCRHRL..RECYHPAFRPIPLQKLVTL.NAHARF.....PI.G.S.SQRFCAAEMTALTNVLM.FCLARILDRRGFETVRAESEFLLFKHASAACRALDLGDVVECSKACLLILAAQASYLNYILGDVAVP.AVCRLHRFVESR--fd....................................................
Q8QS03_9BETA/524-705                 ..........NVLIDVNPRNPSEIVRAALCDYSLSEPYPD...CNDRCVAVFQETGTARRIPNCSHRL..RECYHPAFRPMPLQKLVVC.NPHARF.....PV.S.G.LRRFCMAELAALGNVLG.FCLMRLLDRRGLDEVRLGSEALLFKHAGAACRALENGKLQQCADACLLIMGAQISYHACLLGEHGDS.LLPHALRFVDNKV-s.....................................................
M9TNH0_9BETA/318-497                 ..........NIFLN---HKKEIIFDAVLADYSLSEMHPN...YNGTCAIAKEYDKNLQLVPISRNKF..CDMFNPGFRPLVANAMILV.NVCGAFdgennPL.-.-.--RHCNLDLCAFAQVVL.SCVLRMTDKRGCREAQLYYEKRLFALANEACRLNPLKYPFAYRDACCKVLAEHVVLLGLLFYRDVVE.IYEKLYDFLDERGE......................................................
UL97_HCMVA/461-642                   ..........NVLIDVNPHNPSEIVRAALCDYSLSEPYPD...YNERCVAVFQETGTARRIPNCSHRL..RECYHPAFRPMPLQKLLIC.DPHARF.....PV.A.G.LRRYCMSELSALGNVLG.FCLMRLLDRRGLDEVRMGTEALLFKHAGAACRALENGKLTHCSDACLLILAAQMSYGACLLGEHGAA.LVSHTLRFVEAKMS......................................................
A0A0G2UGM1_SCMVC/352-534             ..........NVLINVNPHYPSEILHAVLCDYSLSEPYPV...CNDRCVVVFQETGTARRIPNCTHRV..RECYHPAFRPLPLQKLMIS.NPHARF.....PDnS.M.LRRFCMAELAALGNVLG.FCLVRLLDRRGIREVQGGPEMMLFKHASTACRALEHNRLTACSDACMLIMAAQLAYHACLLGNDGLS.IVNRTVNFVESKL-s.....................................................
B3UX44_MUHV1/396-576                 ..........NVLINYDRADDRQIARAVICDFSLSQCHTE..gTTGHCVVVFQQTKTVRALPKSAYYL..TDIYHPAFKPLMLQKLCAI.EPRKQF.....PK.P.S.ANRFCVSDLCALGHVAA.FCLVRVLDERGQLKVRSTSEDALFGVARKTCDALARHSVDEVANFCSLLITRQLAYTATLLGSDD--.--------------mrepmarlcdyfet........................................
G8XTZ3_SCMVC/347-529                 ..........NVLINVNPHYPSEILHAVLCDYSLSEPHPI...CNDRCVVVFQETGTARRIPNCAHRV..RECYHPAFRPLPLQKLMIC.NPHARF.....PD.NhT.QRRFCMIELAALGNVLA.FCLVRLLDRRGIRDVQASIEALLFKHAATACRALENNRLTACSDACMLIMAAQLSYHAGLLGDEGLS.IVNRTVTFVEAKMS......................................................
A8E1L5_MUHVK/396-576                 ..........NVLINYDRADDRQIARAVICDFSLSQCHTE..gTTGHCVVVFQQTKTVRALPKSAYYL..TDIYHPAFKPLMLQKLCAI.EPRKQF.....PK.P.S.ANRFCVSDLCALGHVAA.FCLVRVLDERGQLKVRSTSEDALFGVARKTCDALARHSVDEVANFCSLLITRQLAYTATLLGSDD--.--------------mrepmarlcdyfet........................................
#=GC seq_cons                        ..........NlLINhs.ppsppIl+AVLCDYSLSEsHPs...hNc+CllVFQpTtTsRtlPpssa+L..p-sYHPAFRPLsLQKlhls.sP+upF.....Pl.s.s..pRFCsh-LsALGpVls.FCLlRlLDcRGhccV+hssEshLFphAspACcALttpplpshusAChhlhAtQluYhusLLGccsht.hhpphhpFlctp........................................................
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