#=GF ID WHD_Cdc6
#=GF AC PF09079.18
#=GF DE CDC6, C terminal winged helix domain
#=GF PI Cdc6_C;
#=GF AU Sammut SJ;0000-0003-4472-904X
#=GF SE pdb_1fnn
#=GF GA 25.10 25.10;
#=GF TC 25.10 25.10;
#=GF NC 25.00 25.00;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 -Z 90746521 --cpu 8 HMM pfamseq
#=GF TP Domain
#=GF WK Cdc6
#=GF CL CL0123
#=GF RN [1]
#=GF RM 11030343
#=GF RT Structure and function of Cdc6/Cdc18: implications for origin
#=GF RT recognition and checkpoint control.
#=GF RA Liu J, Smith CL, DeRyckere D, DeAngelis K, Martin GS, Berger JM;
#=GF RL Mol Cell. 2000;6:637-648.
#=GF DR INTERPRO; IPR015163;
#=GF DR SCOP; 1fnn; fa;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC The C terminal domain of CDC6 assumes a winged helix fold, with
#=GF CC a five alpha-helical bundle (alpha15-alpha19) structure, backed
#=GF CC on one side by three beta strands (beta6-beta8). It has been
#=GF CC shown that this domain acts as a DNA-localisation factor,
#=GF CC however its exact function is, as yet, unknown. Putative
#=GF CC functions include: (1) mediation of protein-protein interactions
#=GF CC and (2) regulation of nucleotide binding and hydrolysis.
#=GF CC Mutagenesis studies have shown that this domain is essential for
#=GF CC appropriate Cdc6 activity [1].
#=GF SQ 4376
#=GS A0A3P6UBN8_LITSI/648-740 AC A0A3P6UBN8.1
#=GS A0A0H1BCZ0_9EURO/581-645 AC A0A0H1BCZ0.1
#=GS A0A0R3QSJ7_9BILA/586-678 AC A0A0R3QSJ7.1
#=GS A0A151IEJ0_9HYME/450-542 AC A0A151IEJ0.1
#=GS A0A6P5S581_PRUAV/681-773 AC A0A6P5S581.1
#=GS A0A8X6PB71_NEPPI/773-865 AC A0A8X6PB71.1
#=GS A0A6J0ULE2_9SAUR/510-601 AC A0A6J0ULE2.1
#=GS A0A8S3T134_MYTED/345-437 AC A0A8S3T134.1
#=GS A0A7L1FLX4_SYLBO/758-850 AC A0A7L1FLX4.1
#=GS A0A498G0Y6_9EURY/289-384 AC A0A498G0Y6.1
#=GS A0A7J7HPE3_CAMSI/170-221 AC A0A7J7HPE3.1
#=GS A0A166E7G6_9EURY/290-382 AC A0A166E7G6.1
#=GS L0I8T1_HALRX/467-561 AC L0I8T1.1
#=GS A0AAD9J3D5_9ANNE/810-902 AC A0AAD9J3D5.1
#=GS A0A8C8VE66_9SAUR/541-633 AC A0A8C8VE66.1
#=GS A0A540MQ99_MALBA/420-513 AC A0A540MQ99.1
#=GS A0A3Q0J6Z7_DIACI/430-522 AC A0A3Q0J6Z7.1
#=GS L0K0E5_9EURY/292-390 AC L0K0E5.1
#=GS A0A7D5E4E6_9EURY/290-386 AC A0A7D5E4E6.1
#=GS A0A3L6PGQ3_PANMI/706-798 AC A0A3L6PGQ3.1
#=GS A0A6P5RYB5_PRUAV/681-768 AC A0A6P5RYB5.1
#=GS G0MKX5_CAEBE/543-638 AC G0MKX5.1
#=GS H0VGK9_CAVPO/471-563 AC H0VGK9.2
#=GS A0A8C5GQW1_GOUWI/463-554 AC A0A8C5GQW1.1
#=GS A7EGS4_SCLS1/484-578 AC A7EGS4.1
#=GS A0A2V1CR70_9HELO/446-540 AC A0A2V1CR70.1
#=GS A0A672YQD4_9TELE/683-775 AC A0A672YQD4.1
#=GS M7B8T8_CHEMY/743-835 AC M7B8T8.1
#=GS A0A674I0P0_9SAUR/602-694 AC A0A674I0P0.1
#=GS A0AA47P2P4_MERPO/865-957 AC A0AA47P2P4.1
#=GS F4WN23_ACREC/298-390 AC F4WN23.1
#=GS A0A8C0VKE2_CYACU/455-547 AC A0A8C0VKE2.1
#=GS G0VKE5_NAUCA/425-523 AC G0VKE5.1
#=GS A0A0D9V7Y3_9ORYZ/406-498 AC A0A0D9V7Y3.1
#=GS A0A9P6MBP4_9FUNG/691-784 AC A0A9P6MBP4.1
#=GS A0A8B8JVC9_ABRPR/359-450 AC A0A8B8JVC9.1
#=GS A0A1I7VMF9_LOALO/285-371 AC A0A1I7VMF9.1
#=GS A0A4Q4VQJ4_9PEZI/471-568 AC A0A4Q4VQJ4.1
#=GS A0A8U1C075_SALNM/836-928 AC A0A8U1C075.1
#=GS A0AAE1QTS4_9SOLA/714-806 AC A0AAE1QTS4.1
#=GS A0AAE0TXC1_9PEZI/478-577 AC A0AAE0TXC1.1
#=GS A0AAJ0C4F0_9PEZI/489-586 AC A0AAJ0C4F0.1
#=GS A0A256H942_9EURY/301-397 AC A0A256H942.1
#=GS V4BTT9_LOTGI/296-388 AC V4BTT9.1
#=GS R1EP16_BOTPV/525-589 AC R1EP16.1
#=GS A0A6B9FC70_9EURY/290-385 AC A0A6B9FC70.1
#=GS A0A518S7V3_9EURY/301-397 AC A0A518S7V3.1
#=GS A0A0R3P9T4_ANGCS/501-582 AC A0A0R3P9T4.1
#=GS A0A1H6IB83_9EURY/293-389 AC A0A1H6IB83.1
#=GS A0A2Z6MVI9_TRISU/305-396 AC A0A2Z6MVI9.1
#=GS A0A7F8QCU5_LEPWE/232-305 AC A0A7F8QCU5.1
#=GS A0A2K5VLB1_MACFA/491-583 AC A0A2K5VLB1.1
#=GS A0A151A9Z1_9EURY/118-213 AC A0A151A9Z1.1
#=GS A0A2R6X2E4_MARPO/1189-1281 AC A0A2R6X2E4.1
#=GS A0A200QTQ6_MACCD/414-505 AC A0A200QTQ6.1
#=GS A0A9R1UDJ4_LACSA/394-485 AC A0A9R1UDJ4.1
#=GS A3DMN8_STAMF/296-389 AC A3DMN8.1
#=GS A0A8B6H2K4_MYTGA/637-729 AC A0A8B6H2K4.1
#=GS A0AA39CBV6_9EURO/463-556 AC A0AA39CBV6.1
#=GS A0A5A7Q4Q3_STRAF/427-518 AC A0A5A7Q4Q3.1
#=GS A0A0V0RQ71_9BILA/1327-1419 AC A0A0V0RQ71.1
#=GS A0A7K4KXM4_9AVES/139-231 AC A0A7K4KXM4.1
#=GS A0A9Q3DFK2_9BASI/780-871 AC A0A9Q3DFK2.1
#=GS A0A7L9FGY3_9CREN/288-383 AC A0A7L9FGY3.1
#=GS CDC6N_HALMA/300-400 AC Q5V7E8.2
#=GS A0A1D6N6X5_MAIZE/378-470 AC A0A1D6N6X5.1
#=GS A0A2K5NRX5_CERAT/762-854 AC A0A2K5NRX5.1
#=GS CDC6I_HALMA/307-405 AC Q5V385.2
#=GS A0A8V1A4S7_CHICK/771-862 AC A0A8V1A4S7.1
#=GS A0A9Y1ZAG3_9EURY/317-414 AC A0A9Y1ZAG3.1
#=GS A0A150VCU5_9PEZI/441-538 AC A0A150VCU5.1
#=GS A0A4W6D012_LATCA/523-615 AC A0A4W6D012.1
#=GS A0A1H5X419_9EURY/490-584 AC A0A1H5X419.1
#=GS A0A9Q8SMI2_9PEZI/536-600 AC A0A9Q8SMI2.1
#=GS A0A0W7THU2_9ARCH/296-392 AC A0A0W7THU2.1
#=GS A0A9P4VUN3_9PEZI/541-602 AC A0A9P4VUN3.1
#=GS A0A554MUU5_9EURY/318-416 AC A0A554MUU5.1
#=GS A0A6J1DLH3_MOMCH/689-781 AC A0A6J1DLH3.1
#=GS A0A804NAR5_MAIZE/378-470 AC A0A804NAR5.1
#=GS A0A078FDV2_BRANA/400-496 AC A0A078FDV2.1
#=GS A0A1C1CDH4_9EURO/459-552 AC A0A1C1CDH4.1
#=GS G8BU65_TETPH/467-566 AC G8BU65.1
#=GS A0A1V4JY62_PATFA/760-852 AC A0A1V4JY62.1
#=GS A0A6I9YYX8_9SAUR/467-558 AC A0A6I9YYX8.1
#=GS A0AAD9QHV5_ACRCE/49-140 AC A0AAD9QHV5.1
#=GS A0A9N9WTK9_9DIPT/458-550 AC A0A9N9WTK9.1
#=GS A0A672K2L0_SINGR/791-883 AC A0A672K2L0.1
#=GS A0A834M3B0_RHYFE/626-718 AC A0A834M3B0.1
#=GS A0A1N7FLI0_9EURY/297-394 AC A0A1N7FLI0.1
#=GS A0A6J1ZF84_ACIJB/734-826 AC A0A6J1ZF84.1
#=GS A0A0A7LC11_9ARCH/283-377 AC A0A0A7LC11.1
#=GS A0A669PT72_PHACC/445-535 AC A0A669PT72.1
#=GS A0A8J8PZR6_9EURY/296-394 AC A0A8J8PZR6.1
#=GS A0A364LDU9_TALAM/486-579 AC A0A364LDU9.1
#=GS A0A2T6ZIH5_TUBBO/495-595 AC A0A2T6ZIH5.1
#=GS A0A1A6GN68_NEOLE/388-473 AC A0A1A6GN68.1
#=GS A0A6J3B825_VICPA/358-450 AC A0A6J3B825.1
#=GS A0A4D7HAY2_9EURY/336-433 AC A0A4D7HAY2.1
#=GS A0A8X7WPQ2_BRACI/408-499 AC A0A8X7WPQ2.1
#=GS S8DP81_9LAMI/403-495 AC S8DP81.1
#=GS D2HR21_AILME/451-543 AC D2HR21.1
#=GS D3SVN2_NATMM/299-395 AC D3SVN2.1
#=GS A0A9B0LPY2_ODORO/768-860 AC A0A9B0LPY2.1
#=GS A0A9P5QN54_9FUNG/575-668 AC A0A9P5QN54.1
#=GS A0A1H6J5R1_9EURY/278-370 AC A0A1H6J5R1.1
#=GS A0A6A7LGQ9_9ARCH/307-396 AC A0A6A7LGQ9.1
#=GS A0A914FK77_9BILA/274-353 AC A0A914FK77.1
#=GS A9V9J0_MONBE/677-769 AC A9V9J0.1
#=GS A0A8X7C9A0_9ARAC/766-858 AC A0A8X7C9A0.1
#=GS A0A554MVM7_9EURY/324-419 AC A0A554MVM7.1
#=GS A0A1G4MGW5_LACFM/378-477 AC A0A1G4MGW5.1
#=GS A0A6G0Y2Y5_APHCR/362-454 AC A0A6G0Y2Y5.1
#=GS A0A0A2J5G5_PENEN/488-581 AC A0A0A2J5G5.1
#=GS A0A7J5XFH6_DISMA/210-302 AC A0A7J5XFH6.1
#=GS A0A0E9NPN5_SAICN/369-444 AC A0A0E9NPN5.1
#=GS Q74MI0_NANEQ/257-343 AC Q74MI0.1
#=GS A0A1H3JZ49_9EURY/369-467 AC A0A1H3JZ49.1
#=GS B4HK08_DROSE/481-573 AC B4HK08.1
#=GS A0A7N6BRQ7_ANATE/450-541 AC A0A7N6BRQ7.1
#=GS A0A2P4STD0_BAMTH/302-394 AC A0A2P4STD0.1
#=GS CDC63_SULAC/286-373 AC Q4JCP8.1
#=GS A0A091F6K7_CORBR/762-854 AC A0A091F6K7.1
#=GS A0A2B4RSJ8_STYPI/433-524 AC A0A2B4RSJ8.1
#=GS M0ANZ5_NATA1/323-419 AC M0ANZ5.1
#=GS A0A8C5EY65_9SAUR/761-853 AC A0A8C5EY65.1
#=GS A0AAF0MP39_9ARCH/298-390 AC A0AAF0MP39.1
#=GS A0A0F8D777_9EURY/318-416 AC A0A0F8D777.1
#=GS A0A074ZP46_9TREM/371-463 AC A0A074ZP46.1
#=GS A0A1G4K9Q4_9SACH/412-511 AC A0A1G4K9Q4.1
#=GS A0A4Y2SDD1_ARAVE/685-777 AC A0A4Y2SDD1.1
#=GS A0A8J7YQH6_9EURY/304-400 AC A0A8J7YQH6.1
#=GS A0A4U5JC61_9EURY/301-397 AC A0A4U5JC61.1
#=GS A0A8D2MCF7_ZONAL/407-499 AC A0A8D2MCF7.1
#=GS A0A8T9ZYS5_9EURY/380-474 AC A0A8T9ZYS5.1
#=GS A0A7K9UAN5_9AVES/141-233 AC A0A7K9UAN5.1
#=GS W9Y9P9_9EURO/472-565 AC W9Y9P9.1
#=GS A0AAD4ILC4_9PLEO/516-611 AC A0AAD4ILC4.1
#=GS A0A667YKU8_9TELE/848-940 AC A0A667YKU8.1
#=GS A0A8B6ZX39_ORYAF/451-543 AC A0A8B6ZX39.1
#=GS A0A835EMX6_9POAL/750-842 AC A0A835EMX6.1
#=GS L9ZDJ8_NATA2/477-571 AC L9ZDJ8.1
#=GS A0A6Q2XX10_ESOLU/442-533 AC A0A6Q2XX10.2
#=GS A0A8K0IXX8_COCNU/374-466 AC A0A8K0IXX8.1
#=GS A0A067QJI7_ZOONE/319-411 AC A0A067QJI7.1
#=GS M0D1F2_9EURY/471-565 AC M0D1F2.1
#=GS A0A9W2Z5G6_BIOGL/536-627 AC A0A9W2Z5G6.1
#=GS A0A2Y9FRQ7_PHYMC/766-858 AC A0A2Y9FRQ7.1
#=GS A1CDB8_ASPCL/487-580 AC A1CDB8.1
#=GS A0A2K2C3A5_POPTR/408-499 AC A0A2K2C3A5.1
#=GS A0A2K5ANI4_9ARCH/296-385 AC A0A2K5ANI4.1
#=GS A0A850ZJM0_9PASS/146-238 AC A0A850ZJM0.1
#=GS U2YET7_9EURY/318-414 AC U2YET7.1
#=GS A0A2J6RMN8_HYAVF/484-577 AC A0A2J6RMN8.1
#=GS A0A1U8Q9D8_NELNU/111-201 AC A0A1U8Q9D8.1
#=GS A0A6B0VJ53_9EURY/198-293 AC A0A6B0VJ53.1
#=GS A0A6F9C883_9TELE/461-552 AC A0A6F9C883.1
#=GS A0A8C3TQH2_CATUS/755-847 AC A0A8C3TQH2.1
#=GS A0A9N8YRN6_9GLOM/398-487 AC A0A9N8YRN6.1
#=GS A0AAF0R906_SOLVR/427-518 AC A0AAF0R906.1
#=GS A0A9W9Z3A5_9CNID/747-839 AC A0A9W9Z3A5.1
#=GS A0A0F7PHN5_9EURY/319-414 AC A0A0F7PHN5.1
#=GS L0A965_CALLD/300-391 AC L0A965.1
#=GS A0A6G0UK82_9BILA/5524-5613 AC A0A6G0UK82.1
#=GS M0LV48_HALLS/296-394 AC M0LV48.1
#=GS A0A9Q1DZB9_CONCO/516-608 AC A0A9Q1DZB9.1
#=GS A0A9P5S343_9FUNG/447-540 AC A0A9P5S343.1
#=GS A0A139HV39_9PEZI/497-593 AC A0A139HV39.1
#=GS A0A232FCK5_9HYME/427-519 AC A0A232FCK5.1
#=GS A0A0T6BEU4_9SCAR/447-538 AC A0A0T6BEU4.1
#=GS A0A671VSL5_SPAAU/850-942 AC A0A671VSL5.1
#=GS I0YJN0_COCSC/468-540 AC I0YJN0.1
#=GS A0A0Q4BF82_9ARCH/286-379 AC A0A0Q4BF82.1
#=GS D3BN28_HETP5/288-384 AC D3BN28.1
#=GS K7F2Y2_PELSI/440-532 AC K7F2Y2.1
#=GS M4AF06_XIPMA/770-862 AC M4AF06.2
#=GS M0L7J1_HALLS/329-424 AC M0L7J1.1
#=GS CDC6_HUMAN/452-544 AC Q99741.1
#=GS A0A9W9KUT9_9EURO/514-607 AC A0A9W9KUT9.1
#=GS A0A428UGI0_9HYPO/455-551 AC A0A428UGI0.1
#=GS A6R7V0_AJECN/504-568 AC A6R7V0.1
#=GS A0A8K0P4C2_LADFU/342-435 AC A0A8K0P4C2.1
#=GS A0A7K5XF99_9CHAR/766-858 AC A0A7K5XF99.1
#=GS I0A1I4_FERFK/298-392 AC I0A1I4.1
#=GS CDC6A_HALSA/293-389 AC Q9HSW6.2
#=GS B4LEL7_DROVI/502-594 AC B4LEL7.1
#=GS A0A9Q1HC49_HOLLE/820-912 AC A0A9Q1HC49.1
#=GS M0DXE5_9EURY/301-396 AC M0DXE5.1
#=GS A0A6G0Y839_APHCR/473-565 AC A0A6G0Y839.1
#=GS A0A310SAG7_9HYME/742-834 AC A0A310SAG7.1
#=GS A0A851YAJ2_9AVES/759-851 AC A0A851YAJ2.1
#=GS A0A7D5GCJ4_9EURY/455-549 AC A0A7D5GCJ4.1
#=GS A0A7K9QZG7_IRECY/774-866 AC A0A7K9QZG7.1
#=GS A0AAF0DMC2_9EURO/484-580 AC A0AAF0DMC2.1
#=GS A0A814AXM1_9BILA/378-470 AC A0A814AXM1.1
#=GS A0A8C1NYG7_CYPCA/566-658 AC A0A8C1NYG7.1
#=GS A0A343TNB1_9EURY/323-418 AC A0A343TNB1.1
#=GS A0A498M391_LABRO/12-73 AC A0A498M391.1
#=GS A0A1V6U2G0_9EURO/493-586 AC A0A1V6U2G0.1
#=GS A0AA90U502_9ARCH/268-361 AC A0AA90U502.1
#=GS A0A6P6KBL2_CARAU/813-905 AC A0A6P6KBL2.1
#=GS W1Q8Q7_OGAPD/19-116 AC W1Q8Q7.1
#=GS A0A8T2PFQ1_9TELE/779-871 AC A0A8T2PFQ1.1
#=GS A0A232LUN1_9EURO/497-598 AC A0A232LUN1.1
#=GS A0A6P3I1D7_BISBB/767-859 AC A0A6P3I1D7.1
#=GS A0A2T7DDN2_9POAL/332-424 AC A0A2T7DDN2.1
#=GS A0A9Q1J3R7_SYNKA/453-544 AC A0A9Q1J3R7.1
#=GS A0A7H9AZB0_ZYGMR/430-529 AC A0A7H9AZB0.1
#=GS A0A1D2R6J3_9ARCH/312-416 AC A0A1D2R6J3.1
#=GS A0A0V1MZ76_9BILA/384-469 AC A0A0V1MZ76.1
#=GS A0A0L0DJ14_THETB/619-711 AC A0A0L0DJ14.1
#=GS A0A8C8XG44_PANLE/451-543 AC A0A8C8XG44.1
#=GS A0A384BYH4_URSMA/451-543 AC A0A384BYH4.1
#=GS A0A151ABF3_9EURY/337-431 AC A0A151ABF3.1
#=GS B4HR31_DROSE/824-916 AC B4HR31.1
#=GS A0A6A6HMU3_VIRVR/537-600 AC A0A6A6HMU3.1
#=GS A0A9R0Z7N5_TRITD/691-783 AC A0A9R0Z7N5.1
#=GS S3DEH7_GLAL2/472-572 AC S3DEH7.1
#=GS A0A1H0AC87_9EURY/296-392 AC A0A1H0AC87.1
#=GS A0A8C6G0V3_MOSMO/453-544 AC A0A8C6G0V3.1
#=GS A0AA97KY16_EUBMA/755-847 AC A0AA97KY16.1
#=GS A0A8J2S0Y3_9CRUS/419-511 AC A0A8J2S0Y3.1
#=GS A0AAF0J0D8_9BASI/404-508 AC A0AAF0J0D8.1
#=GS A0A1X7V3Y9_AMPQE/861-953 AC A0A1X7V3Y9.1
#=GS A0A5J5N310_MUNRE/767-859 AC A0A5J5N310.1
#=GS A0A9P5WJ48_9FUNG/681-773 AC A0A9P5WJ48.1
#=GS F8DCU8_HALXS/298-394 AC F8DCU8.1
#=GS A0A9P7UBP5_9PEZI/491-555 AC A0A9P7UBP5.1
#=GS A0A4U7F398_9EURY/293-389 AC A0A4U7F398.1
#=GS CDC6M_HALMA/312-407 AC Q5V7B0.1
#=GS A0A9P9E7K8_9PLEO/509-604 AC A0A9P9E7K8.1
#=GS A0A158NM71_ATTCE/452-544 AC A0A158NM71.1
#=GS A0A1H6IVH3_9EURY/571-665 AC A0A1H6IVH3.1
#=GS A0A1S3VIF8_VIGRR/370-461 AC A0A1S3VIF8.1
#=GS A0A3M7SJX3_BRAPC/300-390 AC A0A3M7SJX3.1
#=GS A0A7L3DFA9_PLUSO/762-854 AC A0A7L3DFA9.1
#=GS A0A830G3M3_9EURY/292-389 AC A0A830G3M3.1
#=GS A0A4Y2SDB8_ARAVE/671-763 AC A0A4Y2SDB8.1
#=GS A0A834Z203_TETSI/730-822 AC A0A834Z203.1
#=GS A0A8T4GFW9_9EURY/296-393 AC A0A8T4GFW9.1
#=GS A0A8H7YKP4_AJECA/582-652 AC A0A8H7YKP4.1
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A0A9P6J5U7_MORAP/658-750 ................................r-LIQTASLHQ......KLFLV....A..LTA..K...L..........R...R....L.G.................LAE................AE...............F...........S...............E..........V......AHAHLQ....MC..RL...HN.........I......EP.....P.......M.....L......SDLSAI.....C.A.SL....G...SS.....RCL...--.-.........L.VESG....K...QDI.HQ.RV....RL..S.V.SEEDVI--ma....................................................
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A0A8C5RPX2_LATLA/469-556 ...............................da---SSFPLQQ......KILVC....S..LLL..L...T..........K...Q....K.N.................TKE................VN...............L...........G...............K..........L......HEAYSR....IC..QK...QK.........V......GP.....V.......D.....Q......SECLSL.....S.A.LL....E...SR.....GIV...--.-.........G.LKKA....K...EAR.LS.KV....FL..H.-.--------igwen.................................................
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