#=GF ID   X92_N
#=GF AC   PF30215.1
#=GF DE   X92 N-terminal domain
#=GF AU   Morveli N;0000-0003-2496-881X
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   TED:P12304_TED01
#=GF GA   27.00 27.00;
#=GF TC   28.30 35.80;
#=GF NC   20.40 26.40;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 90746521 --cpu 8 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   2474796
#=GF RT   A silent open reading frame of Trypanosoma brucei coding for a
#=GF RT   protein which shares epitopes with the major structural protein
#=GF RT   of the paraflagellar rod.
#=GF RA   Schlaeppi K, Seebeck T;
#=GF RL   Nucleic Acids Res. 1989;17:5399.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This entry represents the N-terminal domain found in X92 and
#=GF CC   related proteins from trypanosomatids. X92 is a protein that
#=GF CC   shares epitopes with the major structural protein of the
#=GF CC   paraflagellar rod and most likely represents a silent open
#=GF CC   reading frame in the Trypanosoma brucei genome [1].
#=GF SQ   17
#=GS A0A3R7K6H7_TRYRA/14-273  AC A0A3R7K6H7.1
#=GS W6KUV9_9TRYP/24-232      AC W6KUV9.1
#=GS K2LW43_TRYCR/2-269       AC K2LW43.1
#=GS A0A0M9G7M0_LEPPY/26-161  AC A0A0M9G7M0.1
#=GS A0A1X0NYF3_9TRYP/2-289   AC A0A1X0NYF3.1
#=GS A4I099_LEIIN/24-176      AC A4I099.1
#=GS A0A7G2CIH5_9TRYP/16-290  AC A0A7G2CIH5.1
#=GS Q4D3V6_TRYCC/2-269       AC Q4D3V6.1
#=GS V5D8G7_TRYCR/2-269       AC V5D8G7.1
#=GS Q4QBB4_LEIMA/2-174       AC Q4QBB4.1
#=GS Q57W88_TRYB2/2-233       AC Q57W88.1
#=GS A4HCS5_LEIBR/3-162       AC A4HCS5.2
#=GS A0A3R7PMG8_9TRYP/2-265   AC A0A3R7PMG8.1
#=GS Q4DYM5_TRYCC/2-269       AC Q4DYM5.1
#=GS A0A061JAU9_TRYRA/40-299  AC A0A061JAU9.1
#=GS F9W852_TRYCI/9-243       AC F9W852.1
#=GS W6L5B1_9TRYP/23-238      AC W6L5B1.1
A0A3R7K6H7_TRYRA/14-273             ......................................................DILRRVLTVQFSRLYELLDEEGMPLLLSWQPLRFQLTLTFSNE.........NGERDRD..GAA......LMAALGESDFCQLWWKLLYTVRILPVVVRAEASPSS.SKTQG--.........QTVPATYGLQQGV..........GCCFRYGVPPF.WEDW..TRVETPP-APGAVLN................VMAAAGRILTVVAEQRD..EAVMPPAVVVNPDT.PEGKLAGA...VPRHLRYTYTFSYVLPELE.......ELHGPL..TLGFVLLLPFPSG....GVDKRGAGDEDDDIMLRALLSAEERKVG.WYRPSFVVLGTCYYQAHVG...........................
W6KUV9_9TRYP/24-232                 .................................................saste--------------------KQLDNLVPRQLLSVRLRISFKNMcdtgdpearCGGGDSE..GVApstllnFLSHVGENNFVEVWKKLFEWVVVVPFLIPRMEANEG.IHAGLIT.........------SG----D..........AGAFHFGTPPF.WEER..HFAQSAREGQRSSYW................LASSAM------EVQCS..AFSAIEASVPINSQ.TS-DAAIS...IPQSIVSEYIFNFTVPEIE.......RALLDIpgIFAFVLILPFG--....----------------------------.-------------------irnaaalslt.................
K2LW43_TRYCR/2-269                  ......................................................NILHRVLAVEFSRISEPLDEKGTPLLLSWQSLRFRLTIGFSNV.........NGELDRE..GAA......LMAALGESDFHLMWRKLFHTVHIVPVILGSAASPPA.DKTHILPe......ldSRATTAGGLQHGV..........GSSFSFGAPQF.WEH-..-RAPAEKNVHVSASN................VMATAGRTLTVVAEQCD..EAVVAPAPVLKTEA.PKKYLKGA...VPGHLHCTYTFSYALPELE.......DFHGPL..TLGFVLLLSFSNGsgkvGTDREGDDDFNDDVLLRALVPMEDRRMA.WYRPSCVVLGTCYYWAHVS...........................
A0A0M9G7M0_LEPPY/26-161             ...........................................pspkgkasklk-------------------------VVSRQLLRFRLTITYDKE.........DGDTGKEqaTQA......FLAMVGIHSLEAAWTFLFSTVQLVPFFASKPKGQSD.QNGQRVPalq..kvgsP----PL-----Spaph.vlsnlGNSFVFGVPVF.WSNH..TYTCANRV-------................-----------------..--------------.--------...-------------------.......------..-------------....----------------------------.-------------------vesrehvyg..................
A0A1X0NYF3_9TRYP/2-289              ......................................................DILRKILVVQLSRVATTVNDDATELVHSWQPLQFRLSITFSNE.........NGEHSRD..GGA......LMARMGESDFASLWRKLFHTVRIVPVVVQSQSSELS.NEDKGASiqwp.qeqeREEKEEKGEEKKIkehekeesrgDKFFSFGTPPF.WST-..TSSPMERNSAFSSSSts............sgLTVVAGKILTVVEGPDS..NIAIQESLSSISSE.HSTDLKKT...IPSCITSVYNFNHTLPDLE.......NYNETV..TIGYVLLLPLLSEkespNEKEKEKKNKKDNIILRALIASEEQSMI.WYRPSSIVLGTCYYRMPVG...........................
A4I099_LEIIN/24-176                 ...........................................rspfapsekmk-------------------------VVSRQLLTFRLTVTYDNM.........AKDASKE..QATk....rFLSMVGIHSLEAAWSHLFGAVQVVPFLLYKTDSSTR.LESEKASspeqassppMPSSASEEWTRCT..........GSVFVCGTPRF.WSSH.rYRWSS-SDAA-----................-----------------..--------------.--------...-------------------.......------..-------------....----------------------------.-------------------akksgstplhgstmtelsmpas.....
A0A7G2CIH5_9TRYP/16-290             ...........................................kslysvttclv-------------------------LEPREVLHLDLEITFENE.........KNKKDSQ..VYA......FLNTVGGADWLSVWKVLFGSLLCTPFLLSSPDTTDS.SSLVGTT.........EVSSSSATPVKAL..........QSTIP-GVPALpLSSI..TRSRTPKEADTSVVHfvfgkttlgvphtgcnINKRDSRFRFSDAFDAS.vGSQVASNLVLSESTlDVRYAEGAaqgIPTFIRSKFEMRFTVPEWEcdpslgpDGFSSR..NLAFLLVMPLSNG....TTSGENT---VRQILLREFITNGPSDMPpWLNHPSIQLGTASM-----cariq......................
Q4D3V6_TRYCC/2-269                  ......................................................NILHRVLVVEFSRLSEPLDEKGTPLLLSWQSLRFRLTIAFSNV.........NGELDRE..GAA......LMAAMGESDFHLMWRKLFHTVRIVPVILGSAASSSA.GKTQNLPe......peSRATTASGLQHGV..........GCFFSFGVPQF.WEN-..-RAPAEKNAQFLASS................VMATAGKILTVAAEQCD..EAVVAPAEVLKAEM.PKPYLKGA...VPSHLHCTYTFSYALPELE.......DFHGPL..TLGFVLLLSFPNGsgkgGTDREGDDDFNDDVLLRALVPVEDQRMA.WYRPSYVVLGTCYYRAHVS...........................
V5D8G7_TRYCR/2-269                  ......................................................NILHRVLVVEFSRLSEPLDEKGTPLLLSWQSLRFRLTIAFSNV.........NGELDSE..GAA......LMAAMGESDFHLMWRKLFHTVRIVPVILGSAASSSA.GKTQSLPe......peSRATTASGLQHGV..........GCFFFFGVPQF.WEN-..-RVPAEKNAQFLASS................VMATAGKILTVAAEPCD..EAVVAPAEVLKAEM.PKQYLKGA...VPSHLHCTYTFSYALPELE.......DFHGPL..TLGFVLLLSFPNGigkgGTDRDGDDDFNDDVLLRALVPVENQRMA.WYRPSYVVLGTCYYRAHVS...........................
Q4QBB4_LEIMA/2-174                  .....................dllhsivkvtfgpvtaaeedpanspfapsekmr-------------------------VVSRQLLTFRLTIAYDNM.........AKDASKE..QAAk....sFLSMVGIHSLEAAWSHLFGAVQVVPFLLCKHDSSTS.LESEKASs......pmQASSPPMPSSASVewi....rctGSAFVCGTPRF.WSSH.rYR-------------................-----------------..--------------.--------...-------------------.......------..-------------....----------------------------.-------------------wsssdatakksgstplhgstmtelpmp
Q57W88_TRYB2/2-233                  ......................................................DILRRTTSVELTRLPVSAADTLSDVVFPWQSLCFRLAMVFNNE.........GGKYDKD..GRA......LMVAVGESNFVLMWRKLFNALCIAPVVVDGSDTQHK.LNAESGS.........-------------..........---LHTSTSSS.WCTYdpTRTGT----------................LGKIAGKLFVVTAKCVS..EGATLETTAPTSGE.VEESGQGKetpIPRRIECVYDFHYTLPDFD.......IWGNDV..TIGFLVMSHYSGN....-----GNVD-----FVRSLDPTASRVKN.LFKSPTVVLGTCHYRAVAS...........................
A4HCS5_LEIBR/3-162                  .......................vlhsflkvtfgpvtaaeedlanspfaptekm------------------------KVVSRQPLTFRLTVTYDNV.........ARDVSKE..QAAk....tFLSMVGVHSLETAWSHLFGAVQVVPFLLYKSDSSAG.SEGEKPSsv.....lqTSSPPMLPFTSEVwi.....nctGSAFVCGTPQF.WSSH..---------------................-----------------..--------------.--------...-------------------.......------..-------------....----------------------------.-------------------rytwslsgatprkdvstp.........
A0A3R7PMG8_9TRYP/2-265              ......................................................DILRRLLAVQFWRLSELVDEEGTPLLLSWQSLRFQLTLTLSNE.........NGERNRD..GAA......LMAALGESDFCLLWRKLFRTLRILPVVVGAAAAPSSpGRTQG--.........QAAPASYGPQHGV..........GCCFRGGVPPF.WEER..TRVEAAPNAQAAASN................VMATAGRILTVAAEPRDevEVEVPRAAVVEAGA.SEGKPQGA...MPRHLSYTYTFSYALPEVE.......ETHRPM..TLGFVLLLPFSSG....GVDKWGAGDAGDDVMLRALLSVQEQKMG.WYRPSFVVLGTCYYQARVG...........................
Q4DYM5_TRYCC/2-269                  ......................................................NILHRVLAVEFLRLSEPLDEKGTPLLLSWQSLRFRLTIAFSNV.........NGELDRE..GAA......LMAAMGESDFHLMWRKLFHTVRIVPVILGSAASPSA.GKTQSLPe......peSRATTASGLQHGV..........GCFFSFGVPQF.WEN-..-RAPAEKNAQFLASS................VMATAGRILTVAAEQCD..EAVVAPAGVLKAEM.PKQYLKGA...VPSHLHCTYTFSYALPELE.......DFHGPL..TLGFVLLLSFPNGsgkgGTDREGDDDFNDDVLLRALVPVEDQRMA.WYRPSYVVLGTCYYRAHVS...........................
A0A061JAU9_TRYRA/40-299             ......................................................DILRRVLAVQFSRLYELLDEEGTPLLLSWQSLRFQLTLTFSNE.........NGEHERD..AAA......LMAALGENDFCRLWWKLLYTVRVLPVVVGAETSPSS.SKTHG--.........QRAPSTYGLQQGV..........GCCFRYGVPPF.WEDR..TRVESPP-APGAVLN................AMAAAGRILTVVAEQRD..EVAMPPMVVVNSDT.PEGKLAGA...VPRHLQYTYTFSYVLPELE.......ELHGPL..TLGFVLLLPFPSG....GVDKRGAGDESDDVMLRALLSAEERKVG.WYRPSFVVLGTCYYQAHVG...........................
F9W852_TRYCI/9-243                  ......................................................DTLRKIVSVKLERLSAAGDETQDGFVSSWQPLRFKLTAALVNE.........DGQSDRG..VMA......LMAAAGESDFRLLWHRLFHVLRITPSVTHGCMEQKS.HEQNG-P.........----------HDL..........GCLPHRATRNR.ALPP..DTAGI-TGEPFTVTA................MGMHGGMAVAP------..VTTTLPAAAENAGR.TPDGSTGE...IPTHMESVYEFHYFLPDVG.......GFQDEI..VVSFTIMTQFFDE....-----SAAE-----IGHSLVSAGGRTGL.LLGPASLALGVCHYRAGV-n..........................
W6L5B1_9TRYP/23-238                 ravstekhfctlvprqllsvrlrisfknecntessgrpsgeedpdvvitstlld-------------------------------------------.........-------..---......FLSHVGEDNFVEAWKRLFECVVVVPFLLPHAEEGEA.VHASL--.........----ATSGD----..........AGAFHFGIPPF.WEEH..RFAQS---VPDGRRP................SCCLAGSAMEVK---CS..TFSVIEESVPTSSE.ALG-TAII...IPQSIVSEYIFSFTVPEVE.......RSLLDVpgVFAFVLMLPFGIS....----------------------------.-------------------namtvsstgdseys.............
#=GC seq_cons                       ..........................................................................p...hllShQsLpFRLTlsasN..........sG-hs+-..suA......hhutlGEssFphhW++LFpsVplVPhllsussossu.scspths.........p.ssss.s.ppsl..........GssFphGsP.F.Wpsh..hRs.s...s.h.s..................hhthAGphhhs.t..ts..thsh..s.s.pst..s.t.httt...lPpplp.hYpFpaslP-lE.......phhtsl..sluFlLhhsasst.........tt.......hh+th.s.t.p.h..hht.s.l.LGss.h................................
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