GenomeNet

Database: Pfam
Entry: bCoV_S1_N
LinkDB: bCoV_S1_N
Original site: bCoV_S1_N 
#=GF ID   bCoV_S1_N
#=GF AC   PF16451.8
#=GF DE   Betacoronavirus-like spike glycoprotein S1, N-terminal
#=GF PI   Spike_NTD;
#=GF AU   Eberhardt R;0000-0001-6152-1369
#=GF SE   PDB:3r4d
#=GF GA   26.00 26.00;
#=GF TC   30.30 33.90;
#=GF NC   22.10 24.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0004
#=GF RN   [1]
#=GF RM   28534504
#=GF RT   Crystal structure of the receptor binding domain of the spike
#=GF RT   glycoprotein of human betacoronavirus HKU1.
#=GF RA   Ou X, Guan H, Qin B, Mu Z, Wojdyla JA, Wang M, Dominguez SR,
#=GF RA   Qian Z, Cui S;
#=GF RL   Nat Commun. 2017;8:15216.
#=GF RN   [2]
#=GF RM   32150576
#=GF RT   Structure of mouse coronavirus spike protein complexed with
#=GF RT   receptor reveals mechanism for viral entry.
#=GF RA   Shang J, Wan Y, Liu C, Yount B, Gully K, Yang Y, Auerbach A,
#=GF RA   Peng G, Baric R, Li F;
#=GF RL   PLoS Pathog. 2020;16:e1008392.
#=GF RN   [3]
#=GF RM   26085157
#=GF RT   Identification of the Receptor-Binding Domain of the Spike
#=GF RT   Glycoprotein of Human  Betacoronavirus HKU1.
#=GF RA   Qian Z, Ou X, Goes LG, Osborne C, Castano A, Holmes KV,
#=GF RA   Dominguez SR;
#=GF RL   J Virol. 2015;89:8816-8827.
#=GF DR   INTERPRO; IPR032500;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This entry represents the N-terminal domain of the
#=GF CC   betacoronavirus-like trimeric spike glycoprotein. The distal S1
#=GF CC   subunit of the coronavirus spike protein is responsible for
#=GF CC   receptor binding. S1 contains two domains; an N-terminal
#=GF CC   galectin-like domain (NTD) and a receptor-binding domain (S1
#=GF CC   RBD) also referred to as the S1 CTD or domain B. Either the S1
#=GF CC   NTD or S1 RBD, or occasionally both, are involved in binding to
#=GF CC   host receptors. S1 NTD is located on the side of the spike
#=GF CC   trimer and mainly recognises sugar receptors [2]. For many
#=GF CC   betacoronaviruses (b-CoVs), for example mouse hepatitis virus
#=GF CC   (MHV), the RBD is located in the NTD. The structure of the MHV
#=GF CC   S1 NTD showed the same fold as human galectins
#=GF CC   (galactose-binding lectin), however it does not bind any sugar;
#=GF CC   instead, it binds to the carcinoembryonic antigen cell-adhesion
#=GF CC   molecule CEACAM1) through protein-protein interactions [2]. All
#=GF CC   three CEACAM21a-binding sites in MHV spikes can be fully
#=GF CC   occupied by CEACAM1a. It has been shown that CEACAM1a binding to
#=GF CC   the MHV spike weakens the interactions between S1 and S2 and
#=GF CC   facilitates the proteolysis of the spike protein and
#=GF CC   dissociation of S1 [2]. The homologous bovine CoV (BCov) S1 NTD
#=GF CC   also possesses a galectin fold but binds to sialic
#=GF CC   acid-containing moieties on host cell membranes, as does the NTD
#=GF CC   of three other group A b-Covs, namely human CoV (HCoV) OC43,
#=GF CC   avian b-CoV, and infectious bronchitis virus (IBV) [3]. Despite
#=GF CC   the S1 NTD of human respiratory b-CoV HKU1 being highly
#=GF CC   homologous to the NTDs of MHV and bovine CoV, it does not bind
#=GF CC   to either sugar or human carcinoembryonic antigen-related cell
#=GF CC   adhesion molecules (CEACAMs) and the RBD is found instead in the
#=GF CC   S1 RBD domain [3].
#=GF SQ   41
#=GS A0A0K1Z074_SARS/33-328   AC A0A0K1Z074.1
#=GS A0A140H1H1_CVHK1/41-328  AC A0A140H1H1.1
#=GS SPIKE_BCHK9/38-360       AC A3EXG6.1
#=GS SPIKE_BCHK9/38-360       DR PDB; 5GYQ A; 6-11;
#=GS C0KYU0_9BETC/43-330      AC C0KYU0.1
#=GS R9UQ53_MERS/49-384       AC R9UQ53.1
#=GS A3EXH4_BCHK9/36-357      AC A3EXH4.1
#=GS U5LNM4_9BETC/43-372      AC U5LNM4.1
#=GS A0A1B3Q5W5_9BETC/45-368  AC A0A1B3Q5W5.1
#=GS Q5DIC5_SARS/33-324       AC Q5DIC5.1
#=GS R9QTA0_SARS/31-327       AC R9QTA0.1
#=GS SPIKE_SARS/33-324        AC P59594.1
#=GS SPIKE_SARS/33-324        DR PDB; 6WAQ B; 321-324;
#=GS SPIKE_SARS/33-324        DR PDB; 5XLR C; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6CRX B; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 5X5B C; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6ACJ A; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 2GHV E; 320-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6NB6 A; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6NB6 B; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6CRZ A; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6CRW A; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 2AJF F; 323-324;
#=GS SPIKE_SARS/33-324        DR PDB; 5WRG C; 261-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6CRW C; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 5X58 A; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6ACG C; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6CS0 B; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6ACD A; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6CS2 C; 33-318;
#=GS SPIKE_SARS/33-324        DR PDB; 6CRW B; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6CS2 B; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 5XLR B; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 5XLR A; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6CS1 C; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6CRV C; 33-315;
#=GS SPIKE_SARS/33-324        DR PDB; 6CS1 A; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6CS0 A; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6ACK A; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 5X58 B; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 3SCI F; 323-324;
#=GS SPIKE_SARS/33-324        DR PDB; 5X4S A; 33-289;
#=GS SPIKE_SARS/33-324        DR PDB; 6CRX C; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6ACK B; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 5X58 C; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6CRX A; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6ACG A; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6VW1 E; 334-337;
#=GS SPIKE_SARS/33-324        DR PDB; 2DD8 S; 321-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6ACC A; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6ACD C; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 2GHV C; 320-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6NB7 C; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 5WRG B; 261-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6ACK C; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6ACC B; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6WAQ D; 320-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6CS1 B; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6VW1 F; 331-337;
#=GS SPIKE_SARS/33-324        DR PDB; 6CS2 A; 33-318;
#=GS SPIKE_SARS/33-324        DR PDB; 2GHW A; 319-324;
#=GS SPIKE_SARS/33-324        DR PDB; 5X5B B; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6CRV A; 33-315;
#=GS SPIKE_SARS/33-324        DR PDB; 6ACC C; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 7JN5 F; 323-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6NB6 C; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 5X5B A; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 3SCI E; 323-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6CRZ C; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 2GHW C; 318-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6CRZ B; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6ACJ B; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6NB7 B; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 5WRG A; 261-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6CRV B; 33-315;
#=GS SPIKE_SARS/33-324        DR PDB; 2AJF E; 323-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6ACG B; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 3SCJ F; 323-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6CS0 C; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6ACJ C; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6ACD B; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 6NB7 A; 33-324;
#=GS SPIKE_SARS/33-324        DR PDB; 3SCJ E; 323-324;
#=GS C6GHS2_9BETC/43-330      AC C6GHS2.1
#=GS A0A0U1WHI2_SARS/31-327   AC A0A0U1WHI2.1
#=GS Q6UZF0_SARS/33-324       AC Q6UZF0.1
#=GS A0A2Z4EVK1_9NIDO/30-358  AC A0A2Z4EVK1.1
#=GS Q6UZF4_SARS/33-324       AC Q6UZF4.1
#=GS SPIKE_BC279/33-328       AC Q0Q475.1
#=GS SPIKE_BCHK4/54-389       AC A3EX94.1
#=GS SPIKE_BCHK4/54-389       DR PDB; 4QZV D; 15-18;
#=GS SPIKE_BCHK4/54-389       DR PDB; 4QZV B; 15-18;
#=GS R9QTH3_SARS/34-328       AC R9QTH3.1
#=GS A0A088DJY6_9BETC/51-358  AC A0A088DJY6.1
#=GS B7U2M2_9BETC/42-332      AC B7U2M2.1
#=GS A0A088DJH4_9BETC/47-350  AC A0A088DJH4.1
#=GS A0A023Y9K3_MERS/19-359   AC A0A023Y9K3.1
#=GS Q9J3E7_9BETC/43-330      AC Q9J3E7.1
#=GS Q9J3E7_9BETC/43-330      DR PDB; 3R4D B; 65-268;
#=GS Q9J3E7_9BETC/43-330      DR PDB; 3R4D D; 65-268;
#=GS I7B987_9BETC/43-330      AC I7B987.1
#=GS A0A1X9JJW0_9ALPC/27-278  AC A0A1X9JJW0.1
#=GS A0A1L7HJ82_9ALPC/23-285  AC A0A1L7HJ82.1
#=GS SPIKE_SARS2/29-337       AC P0DTC2.1
#=GS SPIKE_SARS2/29-337       DR PDB; 7KE4 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KGK A; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND5 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7NEH E; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KKK E; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6VSB B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7NDD B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6VXX B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7L3N B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZOW B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND6 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XM5 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZDG A; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7E7B B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DK3 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CWU C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZDG D; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8U C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K90 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DCX C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DK4 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZP5 A; 2-310;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND9 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XEY B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7MJK B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JZN A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZFO E; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KEC B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CWM C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZXN C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BEJ E; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6Z97 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XM4 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KFV E; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZGH B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8Y B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CHF R; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8M E; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8W B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XKL A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K4N E; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XKP B; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A25 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KS9 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZB4 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JWY C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZER D; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7NDA C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KRS B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CWS Q; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KE9 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JV4 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CN9 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LJR B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND3 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DK5 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND4 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JWB A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XCM A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LQV C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7MJN B; 330-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7L57 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6Z97 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JW0 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JJI C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KJ2 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BEI E; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KEA C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6X29 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KDH C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A5R B; 33-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LY3 A; 29-305;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND9 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CN9 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KJ3 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KJ5 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JV4 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND3 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KMZ C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7MJG C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7AD1 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DD2 K; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CN4 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CDJ E; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CH4 R; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KFY A; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7E23 A; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LY2 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KRR A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CWL A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8U A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8Z B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8Y D; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XKL C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LDJ A; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KDJ C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KDG B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KDJ B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A93 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DK4 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DDD B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KNI A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XF5 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8S C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A29 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KFV B; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KEB C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZDH A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6YM0 E; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JVA A; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CDI E; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XR8 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JVB A; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BNN A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LXZ B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LXY B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A96 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DDN C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XLU B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KJ5 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XLU C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8S B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7L56 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DF4 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7MJJ B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND4 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CM4 A; 332-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CHH A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BYR C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KE9 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BWJ E; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8X C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LQV A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LM8 A; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CWN C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DD8 D; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A5S B; 33-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7L7K A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JWY B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZFO A; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8V B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KKK A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KEB B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CAI C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZGE C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XKL B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XF5 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KJ4 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6W41 C; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZB4 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DK7 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7NDC C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8S A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7EAN A; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KLW A; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KL9 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KNI B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KDI C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XM3 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JMO A; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7E7D C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KMZ B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CH5 R; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZGG B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7AD1 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A4N C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7L0N S; 328-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DCC I; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LXW A; 67-251;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XF6 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DDD C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND8 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K43 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6X6P B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND7 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KJ3 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7C01 A; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CHB R; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KMS C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LXY A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KE9 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BNN C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7E7B C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A95 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7L58 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KDL A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XE1 E; 326-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JW0 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KE8 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6X79 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KE8 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DDN A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KKL A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6YOR E; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KDK A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A93 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KFX A; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KNB A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZXN B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KE7 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LDJ C; 331-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KJ2 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7MJH C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZDH C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CAI A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CHH C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LSS B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7M0J C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CWN A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6LZG B; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KS9 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7AD1 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KN5 B; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A98 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7C2L C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KJ4 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6YZ5 E; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7EAM A; 324-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XC4 Z; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A94 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KKK C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7B18 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JZL B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZB4 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CAC B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BYR A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JJI B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZB5 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XM0 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7M0J A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CWU A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LY3 B; 29-303;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND7 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND8 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DF3 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XS6 B; 29-328;
#=GS SPIKE_SARS2/29-337       DR PDB; 7NDB B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZHD C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KEC C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DK7 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BZ5 A; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6VYB B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JV4 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JW0 E; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KMS A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DK6 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8T B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZGE A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KE4 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A98 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CHC R; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DK5 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BNO C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K4N A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BNO A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZGG C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KDI A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CAK B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7NDD A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K45 B; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7MJM B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7C8V B; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KE6 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DD2 D; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND5 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CWS O; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DCC K; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6X79 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JZN C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KFW A; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A29 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K90 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KL9 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KKL C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XR8 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A95 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A97 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KRQ C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7C8J B; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7L3N A; 29-335;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CWL C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KNE B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZGI B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7MJG B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6Z43 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZER E; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7MJJ A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LXY J; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LXZ K; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8Y E; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XM4 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KS9 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZHD B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KEC A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LO4 B; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KDK C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6VXX A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KRS C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8W A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XCM B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6VYB A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7E7D B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7L56 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DCX K; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BEH E; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DK3 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CN9 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6YLA A; 332-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A5S A; 33-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JWB C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CAB C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LQV B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A25 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZCZ E; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CWN B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7L3N C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6X29 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LDJ D; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DF3 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7B18 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DK4 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KE4 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KDH B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XC3 C; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7MJK A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LSS A; 29-328;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XS6 A; 29-328;
#=GS SPIKE_SARS2/29-337       DR PDB; 6VSB C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KEA B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KFW E; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KJ5 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DX4 E; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CT5 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A5R A; 33-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CN4 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZGI C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BEP C; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CWU B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8U B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KRS A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DK3 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XC4 A; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A97 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XM4 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KNH C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KDH A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8T A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND9 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KDG C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K43 E; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XCN A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6X79 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A94 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KRR B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7MJL A; 332-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CAB A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LY2 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XEY A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6X6P A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8V A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZGH A; 29-328;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JZN B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KDL B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XLU A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BEL X; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8Z C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XKP A; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8W G; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BEO R; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZDH B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7C8W B; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JZM B; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XF6 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6Z43 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JVB B; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A96 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DDD A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LJR A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DF4 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6YOR A; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZOW A; 29-335;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XEY C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DD2 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A91 A; 322-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LXZ A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7L57 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KNB C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CWS R; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XCN C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND4 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6VXX C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KRQ A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7MJJ C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JWY A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A4N A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DD8 E; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6YLA E; 330-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XDG E; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZGH C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CAN B; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DD8 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KMZ A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CWM B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7E7B A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BNN B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7B18 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND3 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8Z A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KDI B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KNH A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7C2L A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8X B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7L7K B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7NDA B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8V C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KDG A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7L58 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XCM C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CT5 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BEP E; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A93 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CWL B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KE6 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KJ3 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7NEG E; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XM0 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XM3 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KRQ B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7MJH B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K4N B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZER A; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KE8 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7NDD C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JZU B; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7MJH A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CAC C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7D4G B; 29-290;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A96 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LX5 B; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CHH B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7MJG A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XCN E; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LSS C; 29-328;
#=GS SPIKE_SARS2/29-337       DR PDB; 7MJI B; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZDG E; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KNB B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6M0J E; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7MJM A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CAI B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6Z43 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A92 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7NDA A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LDJ B; 331-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KRR C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A25 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A95 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KJ2 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CT5 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6X6P C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JZL C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZXN A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KJ4 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7L7K C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KDL C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DK6 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LXX A; 63-265;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LY2 J; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZP5 C; 3-311;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LY0 A; 68-267;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KNE C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7M0J B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KE7 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DK7 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7NDB A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DF4 D; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A97 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XM3 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XM0 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KN6 A; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K43 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A4N B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KNE A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND6 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7LJR C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND8 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZB5 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DK5 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XM5 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KN7 A; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KNI C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BNO B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KE6 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JZL A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KFV A; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7MJM C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JWB B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KDK B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CAK C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND5 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KL9 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BEL R; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BEO X; 335-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BYR B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K90 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZGI A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KKL D; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A29 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KFW B; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CWM A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6X29 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6Z97 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XR8 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KNH B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7L56 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CAK A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7L57 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7L58 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8T C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KDJ A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KEA A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7NDC B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DCX D; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KE7 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7K8X A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XC7 A; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JX3 R; 332-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7JJI A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND6 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KEB A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A98 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZP5 B; 3-233;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XS6 C; 29-328;
#=GS SPIKE_SARS2/29-337       DR PDB; 6VSB A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7EAM B; 324-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DCC E; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XF5 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KN5 A; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7C2L B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BEM E; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7NDC A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KGJ A; 333-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7E7D A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZHD A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZGG A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XF6 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZB5 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7NDB C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6XM5 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7A94 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DDN B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7L0N R; 329-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZGE B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CN4 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CAB B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DF3 A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7BEK E; 334-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7MJK C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7CAC A; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7DK6 C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6ZOW C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 6VYB C; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7ND7 B; 29-337;
#=GS SPIKE_SARS2/29-337       DR PDB; 7KMS B; 29-337;
#=GS A0A240FW18_9ALPC/30-275  AC A0A240FW18.1
#=GS SPIKE_BC133/54-389       AC Q0Q4F2.1
#=GS SPIKE_CVMA5/43-330       AC P11224.2
#=GS SPIKE_CVMA5/43-330       DR PDB; 3JCL A; 43-330;
#=GS SPIKE_CVMA5/43-330       DR PDB; 6VSJ C; 43-330;
#=GS SPIKE_CVMA5/43-330       DR PDB; 6VSJ B; 43-330;
#=GS SPIKE_CVMA5/43-330       DR PDB; 3JCL C; 43-330;
#=GS SPIKE_CVMA5/43-330       DR PDB; 3JCL B; 43-330;
#=GS SPIKE_CVMA5/43-330       DR PDB; 6VSJ A; 43-330;
#=GS U5WI05_SARS/35-325       AC U5WI05.1
#=GS A3EXI2_BCHK9/34-351      AC A3EXI2.1
#=GS SPIKE_BCHK5/56-392       AC A3EXD0.1
#=GS SPIKE_BCHK5/56-392       DR PDB; 5XGR B; 1-4;
#=GS SPIKE_BCHK5/56-392       DR PDB; 5XGR C; 1-4;
#=GS SPIKE_BCHK5/56-392       DR PDB; 5XGR E; 1-4;
#=GS SPIKE_BCHK5/56-392       DR PDB; 5XGR H; 1-4;
#=GS SPIKE_BCHK5/56-392       DR PDB; 5XGR A; 1-4;
#=GS SPIKE_BCHK5/56-392       DR PDB; 5XGR D; 1-4;
#=GS SPIKE_BCHK5/56-392       DR PDB; 5XGR F; 1-4;
#=GS SPIKE_BCHK5/56-392       DR PDB; 5XGR G; 1-4;
#=GS A8JNZ2_9ALPC/24-278      AC A8JNZ2.1
#=GS A8JNZ2_9ALPC/24-278      DR PDB; 6M15 A; 24-278;
#=GS A8JNZ2_9ALPC/24-278      DR PDB; 6M15 C; 24-278;
#=GS A8JNZ2_9ALPC/24-278      DR PDB; 6M15 B; 24-278;
#=GS SPIKE_CVP67/42-332       AC Q8BB25.1
#=GS Q77NQ7_CVM2/43-330       AC Q77NQ7.1
#=GS A0A0K2RVL1_9BETC/42-332  AC A0A0K2RVL1.1
#=GS A0A0A7UZR7_9BETC/43-333  AC A0A0A7UZR7.1
#=GS A3EXJ0_BCHK9/39-359      AC A3EXJ0.1
#=GS B7U2N3_9BETC/42-332      AC B7U2N3.1
A0A0K1Z074_SARS/33-328              .............................vs--SSRRGVYY-NDDIFrSDVLHLTQDYFLPFHSNLTQY.FSLSIQ-......SDKIVYFDNPI...LK........FGD.GIYFAATEKSNV.....IRG----...........----WVFGSTFDNTT..........QSAIIV.NNS...........--THIIIRVC.................YFNLCKDPMYTVSA--.GTQI--SSWVYQ-.....NAFNCTYDRVEkSFQLDTApksg...nfiaLREFVFKNRDGFFTVYQDYTPVNLlr....glPAGLSVLKPILKLPFGINITSFRVVMA...MFS.........KT........tSNYVPESAAYYVGNLKQSTFMLSFNQNGTITDAVDCSQNPLAELKCTTKSFNVSKGIYQTSNFRVAPVTEVV-RFPNITNLCP.........
A0A140H1H1_CVHK1/41-328             ..............................d-VSYGLGTYYILDRVY.LNTSILFTGYFPKSGANFRDL.SLKGTT-......YLSTLWYQKPF...LS.......dFNN.GIFSRVKNTKLY.....VNKTLYS...........EFSTIVIGSVFINNS..........YTIVVQ.PHN...........--GVLEITAC.................QYTMCEYPHTICKSK-.GSFR-NESWHFDK.....SEPLCLFKKNF.TYNVSTD...........WLYFHFYQERGTFYAYYA------........DSGMPTTF-LFSLYLGTLLSHYYVLPL...TCN.........AI........sSNTDNETLQYWVTPLSKRQYLLKFDNRGVITNAVDCSSSFFSEIQCKTKSLLPNTGVYDLSGFTVKPVATVHRRIPDLP-DCD.........
SPIKE_BCHK9/38-360                  ..........................ikakv-----SNV-LLPDPYIaYSGQTLRQNLFMADMSNTILYpVTPPANG......ANGGFIYNTSI...IP........VSA.GLFVNTWMYRQP.....ASSRAYC..........qEPFGVAFGDTFENDR.........iAILIMA.PDNlgsws.avaprNQTNIYLLVC................sNATLCINP-GFNRWGPaGSFIAPDALVD--.....HSNSCFVNNTF.SVNISTS...........RISLAFLFKDGDLLIYHSGWLPTSnfehgfsrGSHPMTYF--MSLPVGGNLPRAQFFQS...IVR.........SNaid...kgdGMCTNFDVNLHVAHLINRDLLVSYFNNGSVANAADCADSAAEELYCVTGSFDPPTGVYPLSRYRAQVAGFVRVTQRGSYCTPP.........
#=GR SPIKE_BCHK9/38-360       SS    ..........................XXXXX-----XXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX......XXXXXXXXXXX...XX........XXX.XXXXXXXXXXXX.....XXXXXXX..........XXXXXXXXXXXXXXXX.........XXXXXXX.XXXXXXXX.XXXXXXXXXXXXXXX................XXXXXXXXX-XXXXXXXXXXXXXXXXXXX--.....XXXXXXXXXXX.XXXXXXX...........XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXX...XXX.........XXXXX...XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEE----.........
C0KYU0_9BETC/43-330                 ...............................DVSKGLGTYYVLDRVY.LNATLLLTGYYPVDGSNYRNL.ALTGTN-......TLSLTWFKPPF...LS.......eFND.GIFAKVQNLKTN.....TPTGATS...........YFPTIVIGSLFGNTS..........YTVVLE.PYN...........--NIIMASVC.................TYTICQLPYTPCKPNTnGNRV-IGFWHTDV.....KPPICLLKRNF.TFNVNAP...........WLYFHFYQQGGTFYAYYADK----........--PSATTF-LFSVYIGDILTQYFVLPF...ICT.........P-.........TAGSTLAPLYWVTPLLKRQYLFNFNEKGVITSAVDCASSYISEIKCKTQSLLPSTGVYDLSGYTVQPVGVVYRRVPNLP-DC-k........
R9UQ53_MERS/49-384                  ...............................DVSKADGIIYPQGRTY.SNITITYQGLFPYQGDHGDMY.VYSAGHAt....gTTPQKLFVANYsqdVK.......qFAN.GFVVRIGAAANS.....TGTVIISpsts..atirkIYPAFMLGSSVGNFSdgkm.grffnHTLVLL.PDG...........CGTLLRAFYCileprsgnhcpagnsytSFATYHTPATDCSD--.GNYNRNASLNSFKe..yfNLRNCTFMYTY.NITEDEI...........LEWFGITQTAQGVHLFSSRYV---........DLYGGNMFQFATLPVYDTIKYYSIIPH...SIR.........SI.........QSDRKAWAAFYVYKLQPLTFLLDFSVDGYIRRAIDCGFNDLSQLHCSYESFDVESGVYSVSSFEAKPSGSVV-EQAEGV-ECD.........
A3EXH4_BCHK9/36-357                 ........................smskvsr--------IF-PDPFVaYSGQTLRQSLYIADTSNTTVY.PITPPPV......GGNPGIYNLTT...LP........VNE.GFLVHTFMYRDQ.....PVDMYCQ...........EPFGVAFGTTFQNDL.........iAIVMIV.PGQygswa.evkrqNTTNVHILVC................gNATLCQYP-AFNRWGPaGSIYSSDAFTT--.....YGESCFINNTF.SINLNTS...........RLNLGFRFSDGNLYIYHSSWLPISgl....nlMLDYPLHY-YMSVGVGSNLPNMQFFQS...VSRkgtppaqgaNNn.......dGSCLAFQNNLYLAYVTRRELLVSYDDNGFPTAVADCSYDAGDELYCVTGSFTPQVGVYPLSRYRAQVSGYVQITQQGDTCV--lp.......
U5LNM4_9BETC/43-372                 ...............................NMSKADGVLYPVERTY.SNITITLEGLFPHQADRGDMY.VYSQSH-......--KGRPFISNYslvTN.......dFGN.GIVIRIGSAANK.....TGSPIISniasnfqimkkLYPALLFGSAVGKFPannktgayfnHSLVIL.PEK...........CGTVITALYCvlepkndtnctgssgyvSYVLFEN--FSCDATTdGNLK-NSLQQWF-.....NIKDCLFEKNY.NVTDDER...........EEWFGIIQDQQGVHLYTSRK----........NGYSNNMFLFATLPIYDQILYYTVMPR...SIN.........AS........nYASYHAFSAFYIYKLHKINYMVDFDVNGYITRAVDCGYNDYTQLQCSYGQFDMDSGVYSASYFNARSRGYYY-EAAELT-ECD.........
A0A1B3Q5W5_9BETC/45-368             ......................yvsvplnkl-------SCLLPDPYMaHSGQTVRQKLYMGNTSNTLVY.PVTPPMFnl.tygNVTPGVYNTSF...LP........VFD.GLLVHTYMNRFAh..ldNPNRTCQ...........EPFGVVFGTTFEQDR.........iAMVIIA.PGEfgmwg.qvnrpNTTFVHVVAC................sNATICAYP-MFNRWGPaGSIHAENSFVE--.....HNSSCFLNDTF.EIPMGTS...........RVNLAFRFQDGNLLLYHTAWLPTEny....tlSGDYPLRY-ARSVGVGSNLPFAQFFQS...VAR.........AR........dSACAFLHNNLYIAPVQPKELLVKYNDQGMPVEIADCSADSTQELYCITGTFTPSVGVYQLSRYRAEAKKLVQVTQQEDSCAIP.........
Q5DIC5_SARS/33-324                  ..............................h-TSSMRGVYY-PDEIFrSDTLYLTQDLFLPFYSNVTGF.-------......HTINHTFDNPV...IP........FKD.GIYFAATEKSNV.....VRG----...........----WVFGSTMNNKS..........QSVIII.NNS...........--TNVVIRAC.................NFELCDNPFFAVSKPM.GTQTHTMIFD---.....NAFNCTFEYISdAFSLDVSeksg...nfkhLREFVFKNKDGFLYVYKGYQPIDVvr....dlPSGFNTLKPIFKLPLGINITNFRAILT...AFS.........PA........qDTWGTSAAAYFVGYLKPTTFMLKYDENGTITDAVDCSQNPLAELKCSVKSFEIDKGIYQTSNFRVVPSGDVV-RFPNITNLCP.........
R9QTA0_SARS/31-327                  ..............................y-SSTFRGVYY-NDDIFrSDVLHLTQDYFLPFNTNVTRY.LSLNAA-......QNTIVYFDNHV...IP........FYD.GIYFAATERSNV.....IRG----...........----WIFGSTFDNRS..........QSAIIV.NNS...........--THILVKVC.................NFVLCTEPMFTVSR--.--NQHYKSWVYQ-.....HARNCTYDVAYpSFQLDVSlknn..vnfqhLREFIFKNVDGFLKIYSSYEPINVvs....giPSGFSVLKPVMSLPLGINITGMRVVMT...MFS.........NT........qANFLTENAAYYVGYLKPRTFMLQFNTNGTIVNAVDCSQDPLSELKCTLKNFNITKGIYQTSNFRVSPTQEVV-RFPNITNRCP.........
SPIKE_SARS/33-324                   ..............................h-TSSMRGVYY-PDEIFrSDTLYLTQDLFLPFYSNVTGF.-------......HTINHTFGNPV...IP........FKD.GIYFAATEKSNV.....VRG----...........----WVFGSTMNNKS..........QSVIII.NNS...........--TNVVIRAC.................NFELCDNPFFAVSKPM.GTQTHTMIFD---.....NAFNCTFEYISdAFSLDVSeksg...nfkhLREFVFKNKDGFLYVYKGYQPIDVvr....dlPSGFNTLKPIFKLPLGINITNFRAILT...AFS.........PA........qDIWGTSAAAYFVGYLKPTTFMLKYDENGTITDAVDCSQNPLAELKCSVKSFEIDKGIYQTSNFRVVPSGDVV-RFPNITNLCP.........
#=GR SPIKE_SARS/33-324        SS    ..............................E-EETTEEEEX-SSSEEESSEEEEEEEEEXXTTEEEEEE.-------......EEBTTBEXXSE...EE........XTT.EEEEEEEESSST.....EEE----...........----EEEESSSSTTS..........EEEEEE.ESS...........--SSEEEEEE.................EEEEESEEEEEEETTT.TSEEEEEEES---.....EEEEEEEEEEEEEXSXXXSXXXS...SEEEEEEEEEEEETTEEEEEEEEEEEEESS....SXXSSEEEEEEEEEEEBXSXXSEEEEEEE...EEE.........XX........XXXBBXXSEEEEEEEXEEEEEEEEEETTSEEEEEEESSSSHHHHHHHHHTSSSXXSEEEEEEEEEEXXEEEEE-ESSSSSSB-T.........
C6GHS2_9BETC/43-330                 ...............................DVSKGLGTYYVLDRVY.LNATLLLTGYYPVHGSMYRNM.ALMGTN-......TLSLNWFEPPF...LS.......eFND.GIYAKVKNLKAS.....LPIGSAS...........YFPTIIIGSNFVNTS..........YTVVLE.PYN...........--GIIMASIC.................QYTICQLPHTYCKPNTgGNTL-IGFWHTDL.....RSPVCILTRNF.TFNVNAE...........WLYFHFYQQGGTFYAYYA------........DVSSATTF-LFSSYIGAVLTQYFVLPY...MCN.........P-.........TTSGVFSPQYWVTPLVKRQYLFNFNQKGIITSAVDCASSYTSEIKCKTQSMNPNTGVYDLSGYTVQPVGLVYRRVRNLP-DC-k........
A0A0U1WHI2_SARS/31-327              ..............................y-SSTRRGVYY-NDDIFrSDVLHLTQDYFLPFNTNVTRY.LSLNAA-......QNTIVYFDNHV...IP........FYD.GIYFAATERSNV.....IRG----...........----WIFGSTFDNRS..........QSAIIV.NNS...........--THILVKVC.................NFVLCTEPMFTVSR--.--NQHYKSWVYQ-.....HARNCTYDVAYpSFQLDVSlknn..vnfrhLREFIFKNVDGFLKIYSSYEPINVvs....giPSGFSVLKPIMSLPLGINITGMRVVMT...MFS.........NT........qANFLTENAAYYVGYLKPRTFMLQFNSNGTIVNAVDCSQDPLSELKCTLKNFNVTKGIYQTSNFRVTPTQEVV-RFPNITNRCP.........
Q6UZF0_SARS/33-324                  ..............................h-TSSMRGVYY-PDEIFrSDTLYLTQDLFLPFYSNVTGF.-------......HTINHTFGNPV...IP........FKD.GIYFAATEKSNV.....VRG----...........----WVFGSTMNNKS..........QSVIII.NNS...........--TNVVIRAC.................NFELCDNPFFAVSKPM.GTQTHTMIFD---.....NAFNCTFEYISdAFSLDVSeksg...nfkhLREFVFKNKDGFLYVYKGYQPIDVvr....dlPSGFNTLKPIFKLPLGINITNFRAILT...AFS.........PA........qDIWGTSAAAYFVGYLKPTTFMLKYDENGTITDAVDCSQNPLAELKCSVKSFEIDKGIYQTSNFRVVPSGDVV-RFPNITNLCP.........
A0A2Z4EVK1_9NIDO/30-358             patitntsyfnvnpisivvpefsvartnlvv----------------.------------RQRLQVAAY.DFTKIPI.....tPPHRSIFNNTY...FR........VGD.GILVNTHMYHRTniatnL----GSsfy.....gcqEPFGAAFGNTFVNEP..........ITLVMF.YAGnvgswsslvtqQQANITIVSC................dNATLCANP-FFLRWGP.GVIRSFTISNAFQ....cHGNYTFYDTKLvNFTVSTA...........RYNLAFTFADGDIFMYYAALGDSLn......lPTAYPLQP-YLRIPAGFKPDVVQFFQA...ITR.........PNge....saeVACASSTVSWYVSRLYYKELLVGYDSYSSIVNVSFCSSDAESELQCLLGTFAPANGVYSLSNFRSSPTDNVRITNSASSCSV-p........
Q6UZF4_SARS/33-324                  ..............................h-TSSMRGVYY-PDEIFrSDTLYLTQDLFLPFYSNVTGF.-------......HTINHTFGNPV...IP........FKD.GIYFAATEKSNV.....VRG----...........----WVFGSTMNNKS..........QSVIII.NNS...........--TNVVIRAC.................NFELCDNPFFAVSKPM.GTQTHTMIFD---.....NAFNCTFEYISdAFSLDVSeksg...nfkhLREFVFKNKDGFLYVYKGYQPIDVvr....dlPSGFNTLKPIFKLPLGINITNFRAILT...AFS.........PA........qDIWGTSAAAYFVGYLKPTTFMLKYDENGTITDAVDCSQNPLAELKCSVKSFEIDKGIYQTSNFRVVPSGDVV-RFPNITNLCP.........
SPIKE_BC279/33-328                  .............................vs--SSRRGVYY-NDDIFrSDVLHLTQDYFLPFDSNLTQY.FSLNID-......SNKYTYFDNPI...LD........FGD.GVYFAATEKSNV.....IRG----...........----WIFGSSFDNTT..........QSAIIV.NNS...........--THIIIRVC.................NFNLCKEPMYTVSK--.GTQQ--SSWVYQ-.....SAFNCTYDRVEkSFQLDTApktg...nfkdLREYVFKNRDGFLSVYQTYTAVNLpr....gfPAGFSVLRPILKLPFGINITSYRVVMT...MFS.........QF........nSNFLPESAAYYVGNLKYTTFMLSFNENGTITDAVDCSQNPLAELKCTIKNFNVSKGIYQTSNFRVTPTQEVV-RFPNITNRCP.........
SPIKE_BCHK4/54-389                  .............................dp--SKVDGIIYPLGRTY.SNITLAYTGLFPLQGDLGSQY.LYSVSHAvg..hdGDPTKAYISNYsllVN.......dFDN.GFVVRIGAAANS.....TGTIVISpsvn..tkikkAYPAFILGSSLTNTSagqp..lyanYSLTII.PDG...........CGTVLHAFYCilkprtvnrcpsgtgyvSYFIYETVHNDCQS--.-TINRNASLNSFKs..ffDLVNCTFFNSW.DITADET...........KEWFGITQDTQGVHLYSSRKG---........DLYGGNMFRFATLPVYEGIKYYTVIPR...SFR.........SK.........ANKREAWAAFYVYKLHQLTYLLDFSVDGYIRRAIDCGHDDLSQLHCSYTSFEVDTGVYSVSSYEASATGTFI-EQPNAT-ECD.........
#=GR SPIKE_BCHK4/54-389       SS    .............................XX--XXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXX.XXXXXXXXX..XXXXXXXXXXXXXXXXXX.......XXXX.XXXXXXXXXXXX.....XXXXXXXXXXX..XXXXXXXXXXXXXXXXXXXXXXXX..XXXXXXXXXX.XXX...........XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--.-XXXXXXXXXXXXX..XXXXXXXXXXXXX.XXXXXXX...........XXXXXXXXXXXXXXXXXXXXX---........XXXXXXXXXXXXXXXXXXXXXXXXXXX...XXX.........XX.........XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX--B--.........
R9QTH3_SARS/34-328                  ..............................s--SSKRGVYY-NDDIFrSDVLHLTQDYFLPFHSNLTQY.FSLNVD-......SDRQVYFDNPT...LN........FGD.GVYFAATEKSNV.....IRG----...........----WIFGSTMDNST..........QSAIIV.NNS...........--THIIIRVC.................NFNLCKEPMFTVSR--.--GVHFSSWVYQ-.....SAFNCTYDRVEkSFQLDTApktg...nfkdLREYVFKNRDGFLSVYHSYTPVDIir....giPVGFSVLKPILKLPIGINITSFKVVMT...MYS.........QT........tSNFLSESAAYYVGNLKYVTFMFQFNENGTIADAVDCSQNPLAELKCTLKNFNVSKGIYQTSNFRVSPSTEVI-RFPNITNRCP.........
A0A088DJY6_9BETC/51-358             ............................gky---GFINTYY-PDRIFrSNTTALFTDLFPVIGTTVTPW.KAFNALTt...neRKDKRNFERHP...--........FGE.GVFVTIKHTQVS.....GPS----...........TPPMYLFGTYFNSSS..........YTLAIS.LDG...........--LYRRIEVC.................NFQVCQNPVMYYAK-V.SNPAQGNPLIYSQr..ayTDYNSCVSQTSqSFNITSQgdkngafskdtITTYVFKYQNGIFSVFHGFHNG--........TDHVPYPKPAFEFPLDIPITHFIIPPT...VEE.........PAq.......gQGYTRGNYVVYYAQLKKSTFMFGFDSNGLITRYIDCAAGPKDELMCSQGSFNITPGVYTTTNYRATPKQHVVITSADVSAECP.........
B7U2M2_9BETC/42-332                 ...............................DVTNGLGTYYVLDRVY.LNTTLLLNGYYPTSGSTYRNM.ALKGTL-......LLSTLWFKPPF...LS.......dFTN.GIFAKVKNTKVI.....KDGVMYS...........EFPAITIGSTFVNTS..........YSVVVQ.PHTtnl.....dnkLQGFLEISVC.................QYTMCEYPNTICNPNL.GNQR-VELWHWDT.....GVVSCLYKRNF.TYDVNAD...........YLYFHFYQEGGTFYAYFT------........DTGVVTKF-LFNVYLGTVLSHYYVMPL...TCN.........S-.........----ALTLEYWVTPLTSKQYLLAFNQDGVIFNAVDCKSDFMSEIKCKTLSIAPSTGVYELNGYTVQPIADVYRRIPNLP-DCN.........
A0A088DJH4_9BETC/47-350             ..............................n-LTVNHDTFLIPQPTF.-NATTLSAGYYPKIGDTVVTWeAIVTGDSaenqkfKVDYDNYIPHE...--........FGQ.GIVLKVFNRDKA.....SAS----...........TPPAFLFGSTFDNTT..........HTMLIA.VNT...........--THRTVAVC.................RFEFCSTPVVASMINN.GNFQQYNHSSLFT.....SAEDCIYVN-YqNFTMNNTmgdl...srtgTVYYSFQYLNGYFSIYYAYRALHN........LTEPKFLSPFMHFPLSIAVTNFLVPPVwnrNYQ.........NQn.......aQTQARGQFVIEYAMLRLQSMYFDYQN-GTLINYTSC-----DDLSCLTQTPCSTQAPCPTTSCPTQKSTTSVTT---------ttpttistt
A0A023Y9K3_MERS/19-359              ..............................d-ALKADGIIYPTGRSY.SNISLAYQGLFPKQGDLGQQY.VYSVAHAda..nyNKGVQGLGKLF...VSdyatkaetFGD.GFVVRIGAASNS.....TGSVIISqtqk...tikkIYPAFMLGTAVGNFSngvf.glylnHTLVIL.PDG...........CGTNLWVFYCvleprngtkcpnngdyvTYATWDTPYIDCRS--.GGYNANASLNSFKe..yfNLHQCKFMTSY.NITEDEH...........DEWFGVTQNTQGVHLYSSRKG---........DLYGGNMFLFATLPVYETLKYYTVIPR...SIR.........SR.........FYEREAWAAFYVYKLHSLTYLLDFSVDGYIRRAIDCGHDDLAQLRCSYESFDVDTGVYSVSSFEAQPRGSFI-EQAQGT-ECD.........
Q9J3E7_9BETC/43-330                 ..............................e-VSQGLGTYYVLDRVY.LNATLLLTGYYPVDGSKFRNL.ALTGTN-......SVSLSWFQPPY...LS.......qFND.GIFAKVQNLKTS.....TPSGATA...........YFPTIVIGSLFGYTS..........YTVVIE.PYN...........--GVIMASVC.................QYTICQLPYTDCKPNTnGNKL-IGFWHTDV.....KPPICVLKRNF.TLNVNAD...........AFYFHFYQHGGTFYAYYADK----........--PSATTF-LFSVYIGDILTQYYVLPF...ICN.........P-.........TAGSTFAPRYWVTPLVKRQYLFNFNQKGVITSAVDCASSYTSEIKCKTQSMLPSTGVYELSGYTVQPVGVVYRRVANLP-ACN.........
#=GR Q9J3E7_9BETC/43-330      SS    ..............................X-XXXXXXXXXXXXXXX.XXXXXX-EEEB--TT---EE-.--EESS-......EEEGGGCSTTT...SE.......E-TT.EEEEEEE-GGGG.....S-TT---...........-S--EEEESS-STTS..........EEEEEE.EET...........--TEEEEEEE.................E--BBSS--EESS---TT-TT---SSB--S.....S---EEEEEEE.E--TT-S...........EEEEEEEEETTEEEEEEESS----........--TT--EE-EEEEE-SS---EEEE--E...E--.........--.........SSSS-----EEEEE-BEEE-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX.........
I7B987_9BETC/43-330                 ...............................DVSKGRGTYYVLDRVY.LNATLLLTGYYPVDGSNYRNL.ALTGTN-......TLSLTWFKPPF...LS.......eFND.GIFAKVQNLKTN.....TPTGATS...........YFPTIVIGSLFGNTS..........YTVVLE.PYN...........--NIIMASVC.................TYTICQLPYTPCKPNTnGNRV-IGFWHTDV.....KPPICLLKRNF.TFNVNAP...........WLYFHFYQQGGTFYAYYADK----........--PSATTF-LFSVYIGDILTQYFVLPF...ICT.........P-.........TAGSTLAPLYWVTPLLKRQYLFNFNEKGVITSAVDCASSYISEIKCKTQSLLPSTGVYDLSGYTVQPVGVVYRRVPNLP-DC-k........
A0A1X9JJW0_9ALPC/27-278             .........................dqlrqq-------EVYLPNAV-.SNATYIATAVFPT-----RHW.-------......HCGSSSNSTPG...DN.......kFNGiGVFVHRFNHPNW.....-------...........-WHFAAYPAAPTNKT..........WILFWW.HRA...........TQASTVFQVC.................KYQQPAVDVLTSGFRCeAPTNPPCSAIVN-.....MAIECLINSTFrPTTFSFS...........YVTWYNSEINAVIH----------........--GQRFSF-VYEGFLWSNASAF-----...CYD.........--.........-----ANGCIFNIPNTTSDWLVSTDSSGAINNFVDCGFDYESQLKCKNLVFELEPAVYHGAALPIE--SSVYYVANDLA-DC-a........
A0A1L7HJ82_9ALPC/23-285             ..................gnvnldisklyyg----------------.------------TQASINATF.QVVQVLPq...vpWKCNSYSNGPS...NK........FNGiGVFVDLASAQHS.....-------...........-WHLFVYPSMPTNKT..........WILSWA.DTHts......fehGSVISYVQICky.............psNVVTDITNGNGCHTNMaGPGATTCDVILS-.....SPLECVLNRTYsQQYAGVS...........YITWYND------HIIASIQ----........--GEVF-----TFDIGEVLQWS-----...NFS.........A-.........-FCGTGNKCGFSYATTLSEWLVRTDNDGTVIDYVICDTDFESQLKCKNMVFELTPAVYSGSAVELQ--SAIYYVSNELP-DCD.........
SPIKE_SARS2/29-337                  ...........................tnsf----TRGVYY-PDKVFrSSVLHSTQDLFLPFFSNVTWF.HAIHVSG......TNGTKRFDNPV...LP........FND.GVYFASTEKSNI.....IRG----...........----WIFGTTLDSKT..........QSLLIV.NNA...........--TNVVIKVC.................EFQFCNDPFLGVYY--.--HKNNKSWMESEfrvysSANNCTFEYVSqPFLMDLEgkqg...nfknLREFVFKNIDGYFKIYSKHTPINLvr....dlPQGFSALEPLVDLPIGINITRFQTLLA...LHR.........SYltp..gdssSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIV-RFPNITNLCP.........
#=GR SPIKE_SARS2/29-337       SS    ...........................EEES----STTEB--SSSEEESSEEEEEEEEE--TTEEEEEE.EEEEETS......SSSBEEET--E...EE........SSS.EEEEEEEESSSS.....EEE----...........----EEEESSSSSSS..........EEEEEE.EES...........--SEEEEEEE.................EEEEESSEEEEEEE--.--SSSSTTEEEEEEEEEEEEEEEEEEEEESCSSCT-SSSSS...SEEEEEEEEEEEETTEEEEEEEEEEESESS....SS-SSEEEBEEEEEEES-S--SEEEEEEE...EEE.........STSSS..SSTTTSSBESSEEEEEEEEEEEEEEEEECTTSSEEEEEETTSSHHHHHHHHHTSSS-ESEEEEEEEEEB--SEEEE-ESSSSSSBSS.........
A0A240FW18_9ALPC/30-275             ..............................d-LEKITYSLFDLGDVG.VNSTTLINGYFP--SKDINNW.-------......LCEKMGVSELY...--........YGQ.AFYTILNNVGSA.....-------...........SLKFLIQPIVYSNSS..........YVIYMA.YKS...........--GVLNFSIC.................----------------.--YRNYFSFSWDTd..ppSPISCAFNR--.RIYFGHR...........YIYLGVIWRHGYVKIITPNFVQQFe......lDNMYLEVIRVATGRFGSTVNYVIVMPF...QIV.........D-.........---------------KRSTFLVNYNQSGYVSNLLNCSESIEAQLKCKSRSFELQSGVYEIA--LEERVGGYYSVVTNVTGDCN.........
SPIKE_BC133/54-389                  ............................dpa---KVDGIIYPLGRTY.SNITLEYTGLFPLQGDLGMQY.LYSVSHAvg..ndGDPTKAYISNYsllVN.......dFDN.GFVVRIGAAANS.....TGTIVISpsvn..tkikkAYPAFILGSSLTNTSagkp..lyanYSLTII.PDG...........CGTVLHAFYCilkprtgnrcpsgsdynAYFIYETIHSDCQS--.-TINRNASLNSFKs..ffDLVNCTFFNSW.DITADET...........KEWFGITQDTQGVHLHSSRKG---........DLYGGNMFRFATLPVYEGIKYYTVIPR...SFR.........SK.........ANKREAWAAFYVYKLHQLTYLLDFSVDGYIRRAIDCGHDDLSQLHCSYTSFEVDTGVYSVSSYEASATGTFI-EQPNVT-ECD.........
SPIKE_CVMA5/43-330                  ..............................e-VSQGLGTYYVLDRVY.LNATLLLTGYYPVDGSKFRNL.ALRGTN-......SVSLSWFQPPY...LN.......qFND.GIFAKVQNLKTS.....TPSGATA...........YFPTIVIGSLFGYTS..........YTVVIE.PYN...........--GVIMASVC.................QYTICQLPYTDCKPNTnGNKL-IGFWHTDV.....KPPICVLKRNF.TLNVNAD...........AFYFHFYQHGGTFYAYYADK----........--PSATTF-LFSVYIGDILTQYYVLPF...ICN.........P-.........TAGSTFAPRYWVTPLVKRQYLFNFNQKGVITSAVDCASSYTSEIKCKTQSMLPSTGVYELSGYTVQPVGVVYRRVANLP-ACN.........
#=GR SPIKE_CVMA5/43-330       SS    ..............................--GCCSTT-B--TTBB-.-SEEEEEEEEEE-TT-EEEE-.--EESS-......EEEGGGSSTTT...SE.......E-TT.EEEEEEE-GGGC.....S-TT---...........SS-EEEEESS-STTS..........-EEEEE.EET...........--TEEEEEEE.................E--BBSS--EESS---TT-TT-S-SSB--S.....S--EEEEEEEE.E--TT-S...........EEEEEEEEETTEEEEEEESS----........--SS-BEE-EEEEE-SS---EEEEE-E...E--.........--.........TTGCG---EEEEEEEEEEEEEEEE-TTS-EEEEEETTS-HHHHHHHHHTSSS-SSCEEE----------EEEE-------B--.........
U5WI05_SARS/35-325                  ..............................l--SSHRGVYY-PDDIFrSNVLHLVQDHFLPFDSNVTRF.I------......-TFGLNFDNPI...IP........FKD.GIYFAATEKSNV.....IRG----...........----WVFGSTMNNKS..........QSVIIM.NNS...........--TNLVIRAC.................NFELCDNPFFVVLK--.SNNTQIPSYIFN-.....NAFNCTFEYVSkDFNLDLGekpg...nfkdLREFVFRNKDGFLHVYSGYQPISAas....glPTGFNALKPIFKLPLGINITNFRTLLT...AFP.........PR........pDYWGTSAAAYFVGYLKPTTFMLKYDENGTITDAVDCSQNPLAELKCSVKSFEIDKGIYQTSNFRVAPSKEVV-RFPNITNLCP.........
A3EXI2_BCHK9/34-351                 ...........................slsv----SKVTRLVPDPYVaYSGQTIRQSLYYADTSNVTVY.PVTPYAA......PDKTSIYNTSF...VM........VND.GLFVHTYMYLNQ.....PSNMYCQ...........DPFGVAFGTTFEQDH.........iAIVVIA.PDNrgswt.aaskrNVTTVHILVC................sNATLCAYP-AFNRWGPaSSIYASDAFVD--.....HGNSCFVNNSF.DIPINTS...........RINLAFRFLDGNLLLYHSRWLPGSgl....nlATDYPLHF-FMSVGVGANLPNAQFFQS...VVR.........YNrg....vdeARCHTFQNNLYIAPLSLREVLVSYSDSGLPLKVADCAADAGDELFCVTGSFEPAIGVYPLSRYRAQVSDYVHITQQSQACKL-p........
SPIKE_BCHK5/56-392                  ...............................DTSKAEGVIYPNGKSY.SNITLTYTGLYPKANDLGKQY.LFSDGHSa....pGRLNNLFVSNYssqVE.......sFDD.GFVVRIGAAANK.....TGTTVISqstf..kpikkIYPAFLLGHSVGNYTpsnrtgrylnHTLVIL.PDG...........CGTILHAFYCvlhprtqqncagetnfkSLSLWDTPASDCVS--.GSYNQEATLGAFKv..yfDLINCTFRYNY.TITEDEN...........AEWFGITQDTQGVHLYSSRKE---........NVFRNNMFHFATLPVYQKILYYTVIPR...SIR.........SP.........FNDRKAWAAFYIYKLHPLTYLLNFDVEGYITKAVDCGYDDLAQLQCSYESFEVETGVYSVSSFEASPRGEFI-EQATTQ-ECD.........
#=GR SPIKE_BCHK5/56-392       SS    ...............................XXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXX.XXXXXXXX....XXXXXXXXXXXXXXXXX.......XXXX.XXXXXXXXXXXX.....XXXXXXXXXXX..XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXX...........XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--.XXXXXXXXXXXXXX..XXXXXXXXXXXXX.XXXXXXX...........XXXXXXXXXXXXXXXXXXXXX---........XXXXXXXXXXXXXXXXXXXXXXXXXXX...XXX.........XX.........XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXX--B--.........
A8JNZ2_9ALPC/24-278                 ........................lfngifs-----------TSRGL.SNTTTVITGAYP--STNKAKW.-------......FCPTNVGRPVG...TG........VGI.GVYAQTAQASYE.....TGGSGAG...........GYTFSVSPKHVTNLT..........WSLWVHrPWG...........ANANVTVRLC.................--RWWQK-FSFNET--.AHFQPAGPS----.....SAFECLVNGSF.PSS-QHK...........GYMFGVTWYNDFVRIIFP------........----PTVF---ELQLDGLQWEYVQFTG...PVN.........A-.........GRMTK-----FNVVTEISSVLVLTDQSGAVTRYSYCADGFVNGLQCKLRLFDIPPGVYSNSE-VEYPVALYT-VVHNM-----svcp.....
#=GR A8JNZ2_9ALPC/24-278      SS    ........................GGGGG--------------SSEE.SS-EEEEEE------S-GGGE.-------......E----SS--EE...EE........ESS.EEEEEE---TTS.....S-TT---...........---EEEE-SS--TT-..........-EEEEE--SS...........SS-EEEEEEE.................--E-------------.--------S----.....--SEEEEEEEE.E----SS...........-EEEEEE-GGGEEEEEET------........----TEEE---EEE-TT----EEEEE-...---.........--.........----E-----EEEE-S-EEEEEEE-TTS-EEEEEETTSSHHHHHHHHHT-SS--SEEEEEEE-----EEEES---S-------EE--.....
SPIKE_CVP67/42-332                  ...............................DVTNGLGTFYVLDRVY.LNTTLLLNGYYPISGATFRNM.ALKGTR-......LLSTLWFKPPF...LS.......pFND.GIFAKVKNSRFS.....KDGVIYS...........EFPAITIGSTFVNTS..........YSIVVE.PHTsli.....ngnLQGLLQISVC.................QYTMCEYPHTICHPNL.GNQR-IELWHYDT.....DVVSCLYRRNF.TYDVNAD...........YLYFHFYQEGGTFYAYFT------........DTGFVTKF-LFKLYLGTVLSHYYVMPL...TCN.........S-.........----ALSLEYWVTPLTTRQFLLAFDQDGVLYHAVDCASDFMSEIMCKTSSITPPTGVYELNGYTVQPVATVYRRIPDLP-NCD.........
Q77NQ7_CVM2/43-330                  ...............................DVSKGIGTYYVLDRVY.LNATLLLTGYYPVDGSMYRNM.ALTGIN-......TISLNWYKPPF...LS.......eFND.GIFAKVKNLKAS.....LPKDSIS...........YFPTIIIGSNFVTTS..........YTVVLE.PYN...........--GIIMASIC.................QYTICQLPYTDCKPNT.GGNKLIGFWHTEL.....KSPVCILKRNF.TFNVNAE...........WLYFHFYQQGGTFYAYYA------........DVSSATTF-LFSMYIGDVLTQYFVLPY...MCT.........L-.........TTTGVFSPQYWVTPLVKRQYLFNFNQKGIITSAVDCASSYTSEIKCKTQSMNPNTGVYDLSGYTVQPVGLVYRRVRNLP-DC-k........
A0A0K2RVL1_9BETC/42-332             ...............................DVTNGLGTYYVLDRVY.LNTTLLLNGYYPTSGANYRNL.ALKASA-......LLSTLWYKPPF...LS.......eFND.GVFAKVKNTKVT.....KNGIVYS...........EFPTMVIGTTFVNTS..........YTVVVQ.PRTtvv.....nskLQGLLEITIC.................QYSMCEYPNTVCNSGI.GSPR-KELWHYEK.....AVASCLYRRNF.TYDVNSD...........WLYFHFYQQGGTFYAYYT------........DSGFITTF-LFNIYLGTSLSHYYVVPL...SCS.........G-.........----KLDLQYWVTPLTNRQFLLVFNQDGIIYNAVDCASDYMSEIKCNTQNVKPSTGVYDLTGYTVQPIADVYRRIPNLP-DCN.........
A0A0A7UZR7_9BETC/43-333             ...............................DVSNGVGTYYVLNRVY.LNTSLLLTGYYPVSGSIYRNL.LLKGTQ-......WLSTNWFLPPF...LS.......eFNS.GIFVKARNSKPV.....LNGITHS...........EFGTIVFGTSFVNTT..........YTIVIE.PSTqiv.....ngkLIGTLSASVC.................QYTMCEYPNTACNPVL.GNGR-PSLWHASI.....GIVPCLYQRNF.TYNVAAD...........NIYFHFYQDGGTFYAYVG------........DKSPITTL-LFQVYLGTVVTHYYVLPL...VCN.........A-.........----RQTYEYWVTPLIKREYLLVFDGNGVITNAVDCASDHMSEIQCMTQNIKPVTGVYELTGYTVQPIADVYRRIPNLP-DCE.........
A3EXJ0_BCHK9/39-359                 .........................fvvnkl-------STLLPDPYIaYSGQTVRQTLFVANATDTTIY.PITPYKE......GDRAYYYNTSL...YL........VSQ.GFFVHSYMFKNQ.....IEGLYCQ...........QPFGVVFGNTFEQDR.........iAIVIIA.PDVygrwi.tatprSYTNVTILVC................sNATICANP-AFNRWGPaGDYLANNAFTE--.....HDDSCFINNTM.RIPYNTS...........RINLAFRFQDGNLLIYYSDWLPHGsl....dlSAPWPLNF-YTSVAVGGNLKYAQFFQS...VVR.........NYntptqsltdGNCVGDLVNLYVAPLVKRELLVQYSLAGRPINVADCALDSGEELYCVTGTFTPDAGVYSLSRYRAQTVGHVSITQQFETCDIP.........
B7U2N3_9BETC/42-332                 ...............................DVTNGLGTYYVLDRVY.LNTTLLLNGYYPTSGSTYRNM.ALKGTL-......LLSTLWFKPPF...LS.......dFTN.GIFAKVKNTKVI.....KDGVMYS...........EFPAITIGSTFVNTS..........YSVVVQ.PHTtnl.....dnkLQGFLEISVC.................QYTMCEYPNTICNPNL.GNQR-VELWHWDT.....GVVSCLYKRNF.TYDVNAD...........YLYFHFYQEGGTFYAYFT------........DTGVVTKF-LFNVYLGTVLSHYYVMPL...TCN.........S-.........----ALTLEYWVTPLTSKQYLLAFNQDGVIFNAVDCKSDFMSEIKCKTLSIAPSTGVYELNGYTVQPIADVYRRIPNLP-DCN.........
#=GC SS_cons                        ........................GGGCCEC-CCCSTTEB--SSSEEESSEEEEEEEEEE-TTEEEEEE.EEEESSS......EEEGGGCSTTE...EE.......ECTT.EEEEEEEECCCS.....SETT---...........SS-EEEEESSSSTTS..........EEEEEE-EES...........SSTEEEEEEE.................EEEEESSEEEECCCTTTTSTTCSCSSBEESEEEEECEEEEEEEEEECESSTTSSSSSS...SEEEEEEEEEEEETTEEEEEEECCEECESS....SS-SSEEEEEEEEEEECSS--SEEEEEEE...EEE.........STSSS..SSTTTSSBESSEEEEEEEEEEEEEEEEECTTSCEEEEEETTSSHHHHHHHHHTSSS-CSEEEEEEEEEE--EEEEEEESSSSSSBSTEE--.....
#=GC seq_cons                       .................................ophhGsaY..Dcla..ssphLhpsha.stsoshppa.hhhsst.......tsssphFpssh...ls........Fs-.Glascspptpss.....hsu..ht..............shlhGSoasNso..........hollIh.sss.............shlhlplC.................saslCp.Phhssp....Gshp..s.aph.......sshsChappsa.shslsss...........hh.FsFpppsGshalYhu..............ssshsshh.lhslslGtslopahll.t...shs.........s..........sshtstsssaaVs.Lp.ppaLlsaspsGsIssAVDCups.huEL+CpspSFpsssGVYphSsaplpPsupVh.chsNls.cCs.........
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