GenomeNet

Database: Pfam
Entry: bcl-2I13
LinkDB: bcl-2I13
Original site: bcl-2I13 
#=GF ID   bcl-2I13
#=GF AC   PF12201.11
#=GF DE   Bcl2-interacting killer, BH3-domain containing
#=GF AU   Mistry J;0000-0003-2479-5322
#=GF AU   Gavin OL;
#=GF SE   pdb_2ipe
#=GF GA   25.00 25.00;
#=GF TC   25.10 25.20;
#=GF NC   24.20 24.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   9704409
#=GF RT   Bcl-2-family proteins: the role of the BH3 domain in apoptosis.
#=GF RA   Kelekar A, Thompson CB;
#=GF RL   Trends Cell Biol. 1998;8:324-330.
#=GF RN   [2]
#=GF RM   10816098
#=GF RT   Role of the BH3 (Bcl-2 homology 3) domain in the regulation of
#=GF RT   apoptosis and Bcl-2-related proteins.
#=GF RA   Lutz RJ;
#=GF RL   Biochem Soc Trans. 2000;28:51-56.
#=GF RN   [3]
#=GF RM   7478623
#=GF RT   Bik, a novel death-inducing protein shares a distinct sequence
#=GF RT   motif with Bcl-2 family proteins and interacts with viral and
#=GF RT   cellular survival-promoting proteins.
#=GF RA   Boyd JM, Gallo GJ, Elangovan B, Houghton AB, Malstrom S, Avery
#=GF RA   BJ, Ebb RG, Subramanian T, Chittenden T, Lutz RJ, et al.;
#=GF RL   Oncogene. 1995;11:1921-1928.
#=GF RN   [4]
#=GF RM   8816500
#=GF RT   Induction of apoptosis by human Nbk/Bik, a BH3-containing
#=GF RT   protein that interacts  with E1B 19K.
#=GF RA   Han J, Sabbatini P, White E;
#=GF RL   Mol Cell Biol. 1996;16:5857-5864.
#=GF DR   INTERPRO; IPR024579;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is a family of pro-apoptotic Bcl-x proteins, B cell
#=GF CC   leukaemia/lymphoma 2, or BIKs.  BIK proteins rely for their
#=GF CC   activity upon an intact BH3 domain lying between residues 48 and
#=GF CC   80, as in UniProt:Q13323.
#=GF SQ   121
#=GS A0A7N4PH08_SARHA/1-159    AC A0A7N4PH08.1
#=GS A0A096NKG5_PAPAN/1-159    AC A0A096NKG5.2
#=GS Q925D2_RAT/1-157          AC Q925D2.1
#=GS A0A3Q7V097_VULVU/1-149    AC A0A3Q7V097.1
#=GS A0A6J3S4G1_TURTR/18-160   AC A0A6J3S4G1.1
#=GS A0A212CCZ2_CEREH/1-149    AC A0A212CCZ2.1
#=GS A0A6J3S4L0_TURTR/18-147   AC A0A6J3S4L0.1
#=GS A0A0Q3X0L5_AMAAE/1-146    AC A0A0Q3X0L5.1
#=GS A0A6I9LKH4_PERMB/1-158    AC A0A6I9LKH4.1
#=GS A0A1U7Q9K0_MESAU/1-157    AC A0A1U7Q9K0.1
#=GS A0A2Y9Q3A7_DELLE/213-286  AC A0A2Y9Q3A7.1
#=GS A0A2Y9KUM1_ENHLU/19-167   AC A0A2Y9KUM1.1
#=GS G3HXT6_CRIGR/1-125        AC G3HXT6.1
#=GS A0A2Y9L0K6_ENHLU/19-166   AC A0A2Y9L0K6.1
#=GS A0A1S2ZRT7_ERIEU/1-145    AC A0A1S2ZRT7.1
#=GS A0A0D9QZY8_CHLSB/1-158    AC A0A0D9QZY8.1
#=GS A0A384D2B1_URSMA/1-120    AC A0A384D2B1.1
#=GS A0A2Y9Q9M3_DELLE/123-184  AC A0A2Y9Q9M3.1
#=GS W5QCU2_SHEEP/1-147        AC W5QCU2.1
#=GS A0A1S3FUQ7_DIPOR/1-149    AC A0A1S3FUQ7.1
#=GS A0A2R8W6U8_MOUSE/1-143    AC A0A2R8W6U8.1
#=GS A0A093PGF1_PYGAD/1-146    AC A0A093PGF1.1
#=GS A0A093JNT4_FULGA/1-146    AC A0A093JNT4.1
#=GS A0A2K6DBJ4_MACNE/1-159    AC A0A2K6DBJ4.1
#=GS F6SUD3_MACMU/1-159        AC F6SUD3.1
#=GS A0A091QDS8_LEPDC/2-146    AC A0A091QDS8.1
#=GS A0A2Y9PZC3_DELLE/130-219  AC A0A2Y9PZC3.1
#=GS A0A094KEH4_PODCR/1-147    AC A0A094KEH4.1
#=GS BIK_HUMAN/1-159           AC Q13323.2
#=GS A0A7F8QP19_LEPWE/1-148    AC A0A7F8QP19.1
#=GS A0A3Q7PUI4_CALUR/1-148    AC A0A3Q7PUI4.1
#=GS A0A2K5QXZ1_CEBIM/1-155    AC A0A2K5QXZ1.1
#=GS A0A091MKG0_9PASS/1-144    AC A0A091MKG0.1
#=GS A0A5E4BLC3_MARMO/1-134    AC A0A5E4BLC3.1
#=GS A0A1U7TNR6_CARSF/1-164    AC A0A1U7TNR6.1
#=GS A0A3Q2LHE3_HORSE/1-123    AC A0A3Q2LHE3.1
#=GS F7FUT7_CALJA/70-223       AC F7FUT7.2
#=GS A0A4U1EYE0_MONMO/123-170  AC A0A4U1EYE0.1
#=GS A0A669PNF3_PHACC/19-147   AC A0A669PNF3.1
#=GS A0A6J0AKV0_VICPA/1-154    AC A0A6J0AKV0.1
#=GS A0A672UJG6_STRHB/13-147   AC A0A672UJG6.1
#=GS A0A3Q7U4R5_URSAR/1-120    AC A0A3Q7U4R5.1
#=GS A0A091PIC5_HALAL/18-147   AC A0A091PIC5.1
#=GS A0A6P6DDP5_OCTDE/1-154    AC A0A6P6DDP5.1
#=GS E1C005_CHICK/1-147        AC E1C005.1
#=GS E1C005_CHICK/1-147        DR PDB; 5TZP B; 43-64;
#=GS G3QCT2_GORGO/1-159        AC G3QCT2.2
#=GS A0A4D9ECE0_9SAUR/10-152   AC A0A4D9ECE0.1
#=GS A0A5F5XUY6_FELCA/98-245   AC A0A5F5XUY6.1
#=GS A0A2Y9GVZ7_NEOSC/1-125    AC A0A2Y9GVZ7.1
#=GS A0A093C464_TAUER/10-146   AC A0A093C464.1
#=GS A0A6G1B5W9_CROCR/1-122    AC A0A6G1B5W9.1
#=GS A0A091VVC3_OPIHO/1-146    AC A0A091VVC3.1
#=GS A0A7F8K2T9_DELLE/75-136   AC A0A7F8K2T9.1
#=GS A0A2K5VW94_MACFA/10-168   AC A0A2K5VW94.2
#=GS A0A2R8ZXD2_PANPA/1-159    AC A0A2R8ZXD2.1
#=GS A0A2K6TBD7_SAIBB/1-154    AC A0A2K6TBD7.1
#=GS A0A091KZK0_9GRUI/18-146   AC A0A091KZK0.1
#=GS A0A2K5XSA1_MANLE/1-155    AC A0A2K5XSA1.1
#=GS A0A5N4DHE4_CAMDR/1-153    AC A0A5N4DHE4.1
#=GS A0A091W5E1_NIPNI/1-147    AC A0A091W5E1.1
#=GS A0A2K6QK74_RHIRO/1-156    AC A0A2K6QK74.1
#=GS A0A091IU30_EGRGA/1-146    AC A0A091IU30.1
#=GS A0A2K5CLG5_AOTNA/1-154    AC A0A2K5CLG5.1
#=GS A0A2Y9Q9J0_DELLE/213-273  AC A0A2Y9Q9J0.1
#=GS A0A093HL55_STRCA/13-146   AC A0A093HL55.1
#=GS A0A6J0WRF9_ODOVR/93-241   AC A0A6J0WRF9.1
#=GS A0A7N5KDU2_AILME/133-281  AC A0A7N5KDU2.1
#=GS L8HQS1_9CETA/93-216       AC L8HQS1.1
#=GS A0A2K5J4Q7_COLAP/1-159    AC A0A2K5J4Q7.1
#=GS A0A2K6FM79_PROCO/1-151    AC A0A2K6FM79.1
#=GS H0XAE7_OTOGA/1-146        AC H0XAE7.1
#=GS A0A2U4C3H7_TURTR/1-130    AC A0A2U4C3H7.1
#=GS A0A341AS40_NEOAA/1-143    AC A0A341AS40.1
#=GS H0W025_CAVPO/1-158        AC H0W025.2
#=GS A0A6J3GH50_SAPAP/1-139    AC A0A6J3GH50.1
#=GS A0A2I0U3R3_LIMLA/64-207   AC A0A2I0U3R3.1
#=GS A0A2I0MK53_COLLI/19-146   AC A0A2I0MK53.1
#=GS A0A087R1N5_APTFO/1-146    AC A0A087R1N5.1
#=GS A0A5F4W4K0_CALJA/122-275  AC A0A5F4W4K0.1
#=GS A0A5E4BLD2_MARMO/1-150    AC A0A5E4BLD2.1
#=GS A0A455BBN3_PHYMC/1-143    AC A0A455BBN3.1
#=GS A0A2K5LDM6_CERAT/1-155    AC A0A2K5LDM6.1
#=GS G1TZR9_RABIT/1-128        AC G1TZR9.2
#=GS G1PFC4_MYOLU/1-80         AC G1PFC4.1
#=GS BIK_MOUSE/1-149           AC O70337.1
#=GS A0A2R8VI69_MOUSE/1-105    AC A0A2R8VI69.1
#=GS A0A091PDK0_APAVI/1-146    AC A0A091PDK0.1
#=GS A0A663MAW9_ATHCN/1-148    AC A0A663MAW9.1
#=GS A0A091T481_PHALP/1-147    AC A0A091T481.1
#=GS A0A6P3HRX1_BISBI/1-147    AC A0A6P3HRX1.1
#=GS A0A091TTF0_PHORB/1-147    AC A0A091TTF0.1
#=GS A0A6J3GH52_SAPAP/1-155    AC A0A6J3GH52.1
#=GS A0A091FNN6_9AVES/13-146   AC A0A091FNN6.1
#=GS A0A2U3ZCW7_ODORO/1-147    AC A0A2U3ZCW7.1
#=GS A0A6J2N6B9_9CHIR/1-144    AC A0A6J2N6B9.1
#=GS L9KP51_TUPCH/1-151        AC L9KP51.1
#=GS F6RS78_HORSE/46-168       AC F6RS78.2
#=GS I3LVX0_ICTTR/1-106        AC I3LVX0.2
#=GS A0A674KC62_TERCA/10-151   AC A0A674KC62.1
#=GS H2QLU7_PANTR/1-159        AC H2QLU7.1
#=GS A0A2Y9Q3W1_DELLE/212-265  AC A0A2Y9Q3W1.1
#=GS A0A6J2ACU8_ACIJB/1-148    AC A0A6J2ACU8.1
#=GS A0A6P6CWH7_PTEVA/1-140    AC A0A6P6CWH7.1
#=GS A0A663EYV3_AQUCH/18-147   AC A0A663EYV3.1
#=GS A0A099Z8J2_TINGU/1-146    AC A0A099Z8J2.1
#=GS G1S1X2_NOMLE/1-159        AC G1S1X2.2
#=GS A0A673V4V4_SURSU/9-156    AC A0A673V4V4.1
#=GS H2P4N6_PONAB/1-125        AC H2P4N6.2
#=GS A0A3Q7TH07_URSAR/1-149    AC A0A3Q7TH07.1
#=GS A0A2U4C3L6_TURTR/18-138   AC A0A2U4C3L6.2
#=GS A0A2K6MCW0_RHIBE/1-156    AC A0A2K6MCW0.1
#=GS G5BM80_HETGA/1-158        AC G5BM80.1
#=GS A0A1V4K4Z8_PATFA/38-167   AC A0A1V4K4Z8.1
#=GS A0A2Y9KMR9_ENHLU/1-149    AC A0A2Y9KMR9.1
#=GS A0A452H552_9SAUR/10-151   AC A0A452H552.1
#=GS A0A452QUG1_URSAM/38-146   AC A0A452QUG1.1
#=GS A0A093DNA9_9AVES/1-146    AC A0A093DNA9.1
#=GS A0A093R0X3_PHACA/1-146    AC A0A093R0X3.1
#=GS A0A091HF67_BUCRH/6-147    AC A0A091HF67.1
#=GS A0A341AUS9_NEOAA/1-130    AC A0A341AUS9.1
#=GS A0A6P5BEU3_BOSIN/1-147    AC A0A6P5BEU3.1
A0A7N4PH08_SARHA/1-159               msqaralsrrwvplhygqgvvmatapeahygllssslpgateqtefnssaai------------.--------------..------.----......---------.------..----.-QVGHQLAVIGDEINRMYCGKAQDTAPHVApalapVWS..PTFSFIQT.GALSIFRSFVKCFTEPVDS.SWMRRLAAYGNWVP...AppaSTVCRKVIPVALLLILLgL--------vvnygl.....
A0A096NKG5_PAPAN/1-159               ....................................................MSGVRPISRDIL.METLLYEQLLEPL-..TMEVLG.VTDP......EEDLDPMED.FDPLEC..MEDS.DMLALRLACIGDEMDVSLRAPRLAQLSEVA.....MHSlgLAFIYDQTdDIRDVLRSFMDGFTTLRENiMRFWRSPNPRSWVS...R...EQVLLALLLLLALLLAL.LSGGLHLLL...........
Q925D2_RAT/1-157                     ....................................................MSEARLMARDII.-KTLLHDQVPQPAV..VSGAPS.MKEPv....gVEDVSPVRD.LDFMRC..LESR.NQVALRLACIGDEMDRCLRSPRLVQLPGIA.....MHR..LAATYSQT.GVRGIFRSLIGSLTNLREN.IWSWRVFTPGAWVS...P...DQDPGQLFPMVLLVFLL.LGGAWHLQL...........
A0A3Q7V097_VULVU/1-149               ....................................................MSHSGPLSRNLF.LSTFLQEHGPEVL-..--EVPG.MTDL......MEYYDPGPS.PN----..SNNP.DDVAMRLAFIGDEMEVRWMLPRVGELPGMA.....MYS..LAFTYNQT.GLRGVLRSFLDGLANLREN.IRIWSFLTFRNRVS...P...NPGRGLVLSLLLLLVLL.LGWGLRLL-q..........
A0A6J3S4G1_TURTR/18-160              ....................................................MYQARPLSRNLF.LYTFLQNHGPGFLDdqGEGLPG.MTNI......-LEFHPVS-.-----P.ySDGP.HYLAMQLASIADEMELRLLLPQFVEPIRMT.....V--..----YSHI.GLRDILRSFMVAFTNLREN.RSLWSFLTLRDRVS...P...SPWPELALSLLLVVTLS.WGRRL----h..........
A0A212CCZ2_CEREH/1-149               ....................................................MYQARPLSRNLF.LYTFLQNHGPGFLDdqDSGLPG.VT--......-----SILE.FHPVSH..YSDSpHYLAMQLASIADEMELRLLLPQLDEPFWMT.....TYS..LFFPYSHV.GLRDVLRSFMAAFTNLREN.RRLWSFLTLRDRVS...P...SLWP--ELALSLLVVAM.LSWG-----crlh.......
A0A6J3S4L0_TURTR/18-147              ....................................................MYQARPLSRNLF.LYTFLQNHGPGFLDdqGEGLPG.MTNI......-LEFHPVS-.-----P.ySDGP.HYLAMQLASIADEMELRLLLPQFVEPIRMT.....V--..----YSHI.GLRDILRSFMVAFTNLREN.RSLWSFLTLRDRVS...L...DSMT-------------.---------ltyipa.....
A0A0Q3X0L5_AMAAE/1-146               .................msetrrvpghfvlssylngapeeeaysnrqtipdt------------.--------------..------.----......---------.TEQMEF.nISSA.TEVGRQLALIGDEFNRRYHSKFEDTLLHLA.....-HG..VAISVFQ-.-TWNIIRSVIRSSGTILNN.NWTKRIIGYGSWIC...RlpfRCVCQKLVPAALLVVAF.---------wwavnygl...
A0A6I9LKH4_PERMB/1-158               ....................................................MSEARLMARDLI.-KTVLHDQVPRPPV..APGAPS.MKEPv....eEENISPVRD.LDLAEC..LEDR.NQVALRLAYIGDEMDLCLRSPRLAQLPGIA.....MHR..LAVTYSQT.GVRGVFRSLIRGLTNLREN.IWSWRVPTPGTWVL...P...DQARGQLFPMVLLVLLL.LGGEA----lrlql......
A0A1U7Q9K0_MESAU/1-157               ....................................................MSEARLMARDLI.-KTVLHDQVPQPPV..APGAPS.VKEPv....eEENISSMRD.LDLVEC..LEDR.DQVALRLAYIGDEMDLCLRGPRLAQLPGIA.....MHR..LAVTYSQM.GVRGIFRSLIQGLTNLRES.IWSWRVLTPGTWVS...P...NQAGGQLFPTVLLVLLL.LGEALHLQL...........
A0A2Y9Q3A7_DELLE/213-286             .............................................fsephri------------.--------------..------.----......---------.------..----.------------------------------.....-AQ..LVFPYSHI.GLRDVLRSFMVAFTNLREN.RSLWSFLTLRDRVS...P...SPWPELALSLLLVVTLS.WGRRL----h..........
A0A2Y9KUM1_ENHLU/19-167              ....................................................MSHTGPLPRNLF.LSTFLQEHGPEVL-..--EVPG.MTDL......VEYYDPGPS.PNS---..-SNP.DDVAMRLAFIGDEMEVRWTLPRIGELPGMA.....VHS..LAFTYNQM.GLRGVLRSFVDGLTNLREH.IRIWSFLTFRNRVS...P...NPGRGLVLSLLLLVVLL.LGWGLQ---vlq........
G3HXT6_CRIGR/1-125                   ....................................................------------.--------------..------.MKEP.....vEEENSSMRD.LDLVEC..LENR.NQVALRLAYIGDEMDLCLRGARLAQLPGIA.....MHR..LAVNYSQT.GARGIFRSLIRGLTNLREK.IWSWRVLTPGTWVS...P...DQARGQLFPMVLLVLLL.LGEALHLQL...........
A0A2Y9L0K6_ENHLU/19-166              ....................................................MSHTGPLPRNLF.LSTFLQEHGPEVL-..--EVPG.MTDL......VEYYDPGPS.P-----..NSNP.DDVAMRLAFIGDEMEVRWTLPRIGELPGMA.....VHS..LAFTYNQM.GLRGVLRSFVDGLTNLREH.IRIWSFLTFRNRVS...P...NPGRGLVLSLLLLVVLL.LGWGLQ---vlq........
A0A1S2ZRT7_ERIEU/1-145               ....................................................MPQARPVSRGLF.LDTFLYEHIPEAVDipGMTVMA.YSEP......--ESSP---.-D---S..HNRF.NDVAMRLAFIGDEMELRWTMLHLGQLPGMT.....VHS..LAFTYSQT.GVRGVLRSFVESLANLREN.IRFWSFLVFRNRMA...P...SLERDMILSLVLLLVL-.---------wglhll.....
A0A0D9QZY8_CHLSB/1-158               ....................................................MSGVRPISRHIL.MESLLYEQLLEPL-..TMEVLG.VTDP......EEDLDPMED.FDPLEC..MEDS.DMLALRLACIGDEMDVSLRAPRLAQLSEVA.....MHSlgLAFIYDQTdDIRDVLRSFIDGFTTLRENiMRFWRSLNPGSWVS...R...EQVLL-ALLLLALLLAL.LSGGLHLLL...........
A0A384D2B1_URSMA/1-120               ....................................................MSHTGPLSRNLF.LSTFLQEHGPEVL-..--EVPG.MTDL......VEYYDPGPS.PN----..SNNP.DDVAMRLAFIGDEMEVRWMLPRVGELPGMA.....MYS..LAFTYNQT.GLRGVLRSLMDGLTNLREN.IRIWSFLTF-----...-...-----------------.---------rnr........
A0A2Y9Q9M3_DELLE/123-184             .............................................rfsephr------------.--------------..------.----......---------.------..----.------------------------------.....IAQ..LVFPYSHI.GLRDVLRSFMVAFTNLREN.RSLWSFLTLRDRVS...L...DSMT-------------.---------ltyipa.....
W5QCU2_SHEEP/1-147                   ....................................................MYQARPLSRNLF.LYTFLQNHGPGFL-..--DDQG.SGLP......--GVTSILE.FHPISP..YSDSpHYLAMQLASIADEMELRLLLPQFVEPFWMP.....MYS..LCFPYSHV.GLRDVLRSFMVAFTNLREN.RRLWSFLTLRDRVS...P...SLWP--ELALSLLVVAM.LS-------wgcr.......
A0A1S3FUQ7_DIPOR/1-149               ....................................................MSEAGSVTRDLF.IKTLLYQQMPGPRP..AAGLFP.ITEP......----MGEEV.WDPMDC..LEGS.NQVALWLVCIGDEMDQRLRSPRLAQLPGMA.....IHS..LALTYSQM.GVWGVLRRLIRGVAHLRAH.IRAWRPPIPRLQVS...P...GQVRRQMLPAVLLLCGA.---------lqlllq.....
A0A2R8W6U8_MOUSE/1-143               ....................................................MSEARLMARDVI.-KTVPHDQVPQPPV..ASETPS.MKEP......------VRD.VDLMEC..VEGR.NQVALRLACIGDEMDLCLRSPRLVQLPGIA.....IHR..LAVTYSRT.GVRGIFRSLIRSLTNLREN.IWSWRVLTPGAWVS...P...DQDPGQLFPMVLLVFLL.LGG------...........
A0A093PGF1_PYGAD/1-146               .................msqtrriprhfvlssypngapeeetysnlrtiadt------------.--------------..------.----......---------.TEQMEF.nISSA.AQVGHQLALIGDEFNRVYHRKFEDTLLHLA.....-HG..VAISVF--.QTWNIIKSVIRSFGNILNN.NWTKRIIGYGSWIC...RlpfRCVCQKLVPAALLVAA-.---------fwwamnygl..
A0A093JNT4_FULGA/1-146               .................msqtrriprhfvlssypngapeeetysnlqtipdt------------.--------------..------.----......---------.TEQMEF.nISSA.AQVGHQLALIGDEFNRTYHRK----FEDTL.....LHL.aHGVVISVF.QTWNIIKSVVRSFGNILNN.NWTKRIIGYGSWIC...RlpfRCVCQKLVPAALLVAA-.---------fwwamnygl..
A0A2K6DBJ4_MACNE/1-159               ....................................................MSGVRPISRDTL.METLLYEQLLEPL-..TMEVLG.VTDP......EEDLDPMED.FDPLEC..IEDS.DMLALRLACIGDEMDVSLRAPRLAQLSEVA.....MHSlgLAFIYDQMdDIRDVLRSFMDGFTTLRENiMRFWRSPNPRSWVS...R...EQVLLVLLLLLALLLAL.LSGGLHLLL...........
F6SUD3_MACMU/1-159                   ....................................................MSGVRPISRDTL.METLLYEQLLEPL-..TMEVLG.VTDP......EEDLDPMED.FNPLEC..MEDS.DMLALRLACIGDEMDVSLRAPRLAQLSEVA.....MHSlgLAFIYDQMdDIRDVLRSFMDGFTTLRENiMRFWRSPNPRSWVS...R...EQVLLVLLLLLALLLAL.LSGGLHLLL...........
A0A091QDS8_LEPDC/2-146               ..................sqtrriprpfvlssypngapeeetysnlrtipdt------------.--------------..------.----......---------.TEQMEF.nISSA.AQIGHQLALIGDEFNRTYHRKFEDTLLHLA.....-HR..VAVSVFQT.--WNIIKSVIRSFGNILNN.NWTKRIIGCGSWVC...KlpfRCLCQKLVPAALLVVAF.---------wwamnygl...
A0A2Y9PZC3_DELLE/130-219             ....................................fctpscktmalaswmt------------.--------------..------.----......---------.------..----.-----KLASIADEMELRLLLPQFVEPIRMT.....V--..----YSHI.GLRDVLRSFMVAFTNLREN.RSLWSFLTLRDRVS...L...DSMT-------------.---------ltyipa.....
A0A094KEH4_PODCR/1-147               .................msqtrriprhfvlssypngapeeetysnlrtipdt------------.--------------..------.----......---------.TEQMEF.nISSA.TQVGHQLALIGDEFNRSYQRKFEDTLLHLA.....-HG..VAISV--F.QTWNIIKSVLRSFGNILNN.NWTKRIIGYGSWIC...RlpfRCVCQKLVPAAMLLVAF.---------wwamnyglq..
BIK_HUMAN/1-159                      ....................................................MSEVRPLSRDIL.METLLYEQLLEPP-..TMEVLG.MTDS......EEDLDPMED.FDSLEC..MEGS.DALALRLACIGDEMDVSLRAPRLAQLSEVA.....MHSlgLAFIYDQTeDIRDVLRSFMDGFTTLKENiMRFWRSPNPGSWVS...C...EQVLLALLLLLALLLPL.LSGGLHLLL...........
A0A7F8QP19_LEPWE/1-148               ....................................................MSHPGPLSRNLS.WSTFLREHGPEVL-..--EVPG.MTDL......MEYYDPGPS.PNS---..-TNP.DDVAMRLAFIGDEMEVRWMLPRIGELPGMA.....MYS..LAFTYNQT.GLRGVLRSFMDSLSNLRES.IRIWSFLTFRNRVP...P...NPGRGLVLSLLLLLVLL.LG-------wgpqlq.....
A0A3Q7PUI4_CALUR/1-148               ....................................................MSHTGPLSRNLS.WSTFLRERGPEVL-..--EVPG.MTDL......MEYYDPGPS.PNS---..-TSS.DEVAMRLAFIGDEMEVRWMLPRVGEMPGMA.....MYS..LAFTYNQT.GLRGVLRSFTDGLGNLRES.MRIWSFLTFRNRVP...P...NPGRGLVLSLLLLLVLL.LG-------wgpqlq.....
A0A2K5QXZ1_CEBIM/1-155               ....................................................MSEERPLSIDIL.METLLCEQFMDPL-..TMEVVGgGSDP......EEDLDPVE-.-DPLEC..MENS.DALALQLACIADQMDVSLRARKLAQLYEVA.....MYSpgLAVTLDQT.DIRDVLGGIVDIFANFQEDvVRLWRSLSSGSWVS...R...KQAV--LLAFLALLLAT.FSGGLHLLL...........
A0A091MKG0_9PASS/1-144               .................msqtrriprhfvlssypngapeeetysnlqtlpdt------------.--------------..------.----......---------.TEQMEF.dISSA.TQVGHQLALIGDEFNR--RYHR--TLEETL.....LHL.aRLVAVSVF.QTWNIIKSVIRSFGNNLNN.NWTKRIIGYGSWIC...RlpfRCVCQKLVPAALLVAA-.---------fwwamny....
A0A5E4BLC3_MARMO/1-134               ....................................................MSEARPVSRSLL.------RYRPGPLL..AAGASC.MTPPm....gEEVLRLGGN.LHLM--..VQGS.NQVALRLACIGDEMDLCFRGLQLAQLPGMA.....MHS..LALSYSQA.RVTGVLRSLTQGLASLREN.MWFWRPAAPSTRVR...A...KRLQAQL----------.---------apc........
A0A1U7TNR6_CARSF/1-164               ....................................................MSEARPISRDPF.SETLLYEQLREPL-..TVEVLG.LTHSgedpdpEEDPDPVED.FGLMEC..IEGS.DEVALRLACIGDEMDLCLRSSRLAQLPEMA.....MHSlgLALTYDQT.DIRGVLRSFADGFTHLRENvVRFWRSLVPGPWVS...P...GQACEQVLLLVLLLGLL.LGGGLHLML...........
A0A3Q2LHE3_HORSE/1-123               ....................................................MSQVGPVSRDLF.LDAFLHERSPEAL-..--EVPG.MTEL......TES-SPDS-.------..-DNR.DSVAMRLAFIGDEMEVRWMLPHIAELPGVA.....VYS..LAFTYNQT.GLRGVFRSFMDGLTNLREN.IRFWSFLTRRDRVS...L...-----------------.---------rfhdl......
F7FUT7_CALJA/70-223                  ....................................................MSEVRPLSSDIF.METLLCEQFVDPL-..TMEVVG.GSDP......EEDLDPVE-.-DPLEC..MENS.DALALQLACIADQMDVSLRARRLAQLYEVA.....MYSpgLAFVLDRT.DIGDVLSGVVDVFANFQEDiVRLWRSLSSGSWVS...R...KQAV--LLALLALLLAM.FSGGLHLLL...........
A0A4U1EYE0_MONMO/123-170             .............................................rfsephr------------.--------------..------.----......---------.------..----.------------------------------.....IAQ..LVFPYSHI.GLRDVLRSFMVAFTNLREN.RSLWSFLT------...-...-----------------.---------lrd........
A0A669PNF3_PHACC/19-147              ..................................gapeeqtygsllaapdta------------.--------------..------.----......---------.-EQMEL.nISSA.IQVGHQLALIGDEFNRA-YSRKIEDALLHL.....AHR..VAISVFQT.--WNIIRSVTRSFGNFLNN.NWTKRIADYGSWVC...RlpfRCVCQKLVPAALLAVAF.---------wwaisyglq..
A0A6J0AKV0_VICPA/1-154               ....................................................MSQARPVSRNLFfLYTFLQNHGPGSL-..HEQVVG.VPGV......--TVTDVLE.FDPEISpdRDSL.HELAAQLASTADDMELRFVLCQFAELPWMV.....IYS..LFFTYNQT.GLRDVYRSFMYALTNLREN.RRFRNFLAGRGRVF...P...GPWREMVLSLLLGVLL-.---------scgcrlvh...
A0A672UJG6_STRHB/13-147              .............................lssytngapeeetysnrrtipdt------------.--------------..------.----......---------.TEQMEF.nISSA.TQVGRQLALIGDEFNRRYHWKFEDTLLHLA.....-HG..VAIS--VF.QTWNIIRSVIRSFGTILNN.NWTKRIVGYGSWIC...RlpfRCVCQKLVPAALLVVAF.---------wwamnyglq..
A0A3Q7U4R5_URSAR/1-120               ....................................................MSHTGPLSRNLF.LSTFLQEHGPEVL-..--EVPG.MTDL......VEYYDPGPS.PN----..SNNP.DDVAMRLAFIGDEMEVRWMLPRVGELPGMA.....MYS..LAFTYNQT.GLRGVLRSLMDGLTNLREN.IRIWSFLTF-----...-...-----------------.---------rnr........
A0A091PIC5_HALAL/18-147              ..................................ngapeeeiysnlrtipdt------------.--------------..------.----......---------.TEQMEF.nISSA.TQVGHQLALIGDEFNRTYH-RKLEDTLLHL.....AHG..VAI--SVF.QTWNIIKSVIRSFGNILNN.NWTKRIIGYGSWIC...RlpfRCVCQKLVPAALLVVAF.---------wwamnyglq..
A0A6P6DDP5_OCTDE/1-154               ....................................................MSEARPITRDLL.METQLPELLPRPLL..AQGAMR.MTQPl....qGEDLGSSGV.TGLVEC..LEGS.NLVALRLACIGDEMDLRFRSPRLAHLPGRA.....MHS..LAVTYSQT.GLWGVLRKLTHAVTSLGDN.LRAWGRPAPRTWVS...P...TRL----LPAVLLLLLL.LGTL-----rlllq......
E1C005_CHICK/1-147                   .................msqarrsprrvllsrypngapeeqtygsllaapda------------.--------------..------.----......---------.AEQMEL.nISSA.IQVGHQLALIGDEFNRA-YSRKIEDTLLHL.....ARR..VAISVF--.QTWNIIKSVTRSFGNFLNN.NWTKRIAGYGSWVC...RlpfRCVCQKLVPAALLAVAF.---------wwaisyglq..
#=GR E1C005_CHICK/1-147        SS    .................XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------.--------------..------.----......---------.XXXXXX.X--TT.S-HHHHHHHHHHHHHHH--XXXXXXXXXXX.....XXX..XXXXXX--.XXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXX...XXXXXXXXXXXXXXXXXXXXX.---------XXXXXXXXX..
G3QCT2_GORGO/1-159                   ....................................................MSEVRPLSRDIL.METLLYEQLLEPP-..TMEVLG.VTDS......EEDLDPMED.FDSLEC..MEGS.DALALRLACIGDEMDVSLRAPRLAQLSEVA.....MHSlgLAFIYDQTeDIRDVLRSFMDGFTTLKENiMRFWRSPNPGSWVS...R...EQVLLALLLLLALLLPL.LSGGLHLLL...........
A0A4D9ECE0_9SAUR/10-152              ...........................hfvlshdqngvavpneesqnrlltv------------.--------------..------.----......------PDN.TEQMAF.nISSA.TQVGHQLAVIGDEFNSTYTRKLEDMLFHLA.....QGR..MAVNVLKI.LHMHVWKSIIKSFRSLLNN.GWTKRVVAYGSWIS...RlplKSMCQRLMPAALFVILF.---------wwtvsyglq..
A0A5F5XUY6_FELCA/98-245              ....................................................MSHAGPLSRNVF.LSTFLQEHGPEVL-..--DVPG.MTDL......VEYYDPGPS.PNS---..-NSP.DDVAMRLAFIGDEMEVRWMMPRVGELPGMA.....VYS..LAFTYNQT.GLRGVLRSLMDGLANLREN.IWIWGFLTLRNRVS...P...NSGRGLALSLLLLV-LL.LGWGLHLL-q..........
A0A2Y9GVZ7_NEOSC/1-125               ....................................................MSHPGPLSRNLS.WSTFLREHGPEVL-..--EVPG.MTDL......MEYYDPGPS.PNS---..-TNP.DDVAMRLAFIGDEMEVRWMLPRIGELPGMA.....MYS..LAFTYNQT.GLRGVLRSFMDGLSNLRES.IRIWSFLTF-----...-...-----------------.---------rnreclpl...
A0A093C464_TAUER/10-146              .................................hfvlssysnaaleeetysn------------.--------------..------.----......---LQTIPDtTEQMEF.nISSA.TQVGHQLALIGDEFNRRYHRKFEDTLLQLA.....-HG..VAISVFQ-.-TWNIIKSVIRSFGNILNN.NWTKRIIGYGSWIC...KlpfRFVCQKLVPAALLVVAF.---------wwamnygl...
A0A6G1B5W9_CROCR/1-122               ....................................................MSHAGPLSRDVF.LSTFLQEHGPEVL-..--DVPG.MTDL......AEYYDPGPS.PN----..GNSP.DDVAMRLAFIGDEMEVRWMVPRVGELPGMA.....VYS..LAFTYGQT.GLRGVLRSLMEGLANLREN.IRIWSFLTLRN---...-...-----------------.---------rvn........
A0A091VVC3_OPIHO/1-146               .................msqtrriprhfvlssypsgapeeetysnlqtipdt------------.--------------..------.----......---------.TEQMEF.nISSA.AQVGHQLALIGDEFNRTYHRKF----GDTL.....LHL.aQGFSISVF.QTWNIIKSVIRSFGNMLNN.NWTKRIIGCGSWIC...RlpfRCVCQKLVPAALLVVA-.---------cwwamnygl..
A0A7F8K2T9_DELLE/75-136              .............................................rfsephr------------.--------------..------.----......---------.------..----.------------------------------.....IAQ..LVFPYSHI.GLRDVLRSFMVAFTNLREN.RSLWSFLTLRDRVS...L...DSMT-------------.---------ltyipa.....
A0A2K5VW94_MACFA/10-168              ....................................................MSGVRPISRDTL.METLLYEQLLEPL-..TMEVLG.VTDP......EEDLDPMED.FDPLEC..MEDS.DMLALRLACIGDEMDVSLRAPRLAQLSEVA.....MHSlgLAFIYDQMdDIRDVLRSFMDGFTTLRENiMRFWRSPNPRSWVS...R...EQVLLVLLLLLALLLAL.LSGGLHLLL...........
A0A2R8ZXD2_PANPA/1-159               ....................................................MSEVRPLSRDIL.METLLYEQLLEPP-..TMEVLG.VTES......EEDLDPMED.FDSLEC..MEGS.DALALRLACIGDEMDVSLRAPRLAQLSDVA.....MHSlgLAFIYDQTeDIRDVLRSFMDGFTTLKENiMRFWRSPNPRSWVS...R...EQVLLALLLLLALLLPL.LSGGLHLLL...........
A0A2K6TBD7_SAIBB/1-154               ....................................................MSEDRPLSSDIL.METLLCEQFVDPL-..TMEVVG.GSDP......EEDPDSVE-.-DPLEC..MENS.DALALQLACIADQMDVSLRARRLAQLYEVA.....TYSpgLAFILDRT.DIRDVLSGVVDVFADFQEDiVRLWRSLSSGSWVS...G...KQAV--LLALLALLLAM.FSGGLRLLL...........
A0A091KZK0_9GRUI/18-146              .................................ngapeeetysnlqtipdtr------------.--------------..------.----......---------.-EQMEF.nISSA.TQVGHQLALIGDEFNRTYDR----KFEDTL.....LHL.gQGVAISVF.QTWNIIKSVIRSFGNILNN.NWTKRIIGYGSWIC...KlpfRWVCQKLVPAALLVVVF.---------wwamnygl...
A0A2K5XSA1_MANLE/1-155               ....................................................MSGVRPISRDTL.METLLYEQLLEPL-..TMEVLG.VTDP......EEDLDPMED.FDPLEC..MEDS.DMLALRLACIGDEMDVSLRAPRLAQLSEVA.....MHSlgLAFIYDQTdDIRDVLRSFLDGFTTLRENiMRFWRSPNPRSWVS...R...EQV----LLLLALLLAL.LSGGLHLLL...........
A0A5N4DHE4_CAMDR/1-153               ....................................................MSQARPVSRNLFfLYTFLQNHGPGSL-..HEQVVG.VPGV......--TVTDVLE.FDPEISpdRDSL.HELAAQLASTADDMELRFVLCQFAELPWMV.....IYS..LFFTYNQT.GLRDVYRSFMYAVTNLREN.RRFRNFLAGRGRVF...P...GPWREMVLSLLLGVLL-.---------scgcrla....
A0A091W5E1_NIPNI/1-147               .................msqtrriprhfvlssypngapeeetysnlrtipdt------------.--------------..------.----......---------.TEQMEF.nISSA.TQVGRQLALIGDEFNRTYHRKFEDTLLHLA.....-HG..VAISVF--.QTWNIVKSVMRSFGNILNN.NWTKRIIGYGSWIC...RlpfRCVCQQLVPAALLVAAF.---------wwamsyrlq..
A0A2K6QK74_RHIRO/1-156               ....................................................MSGVRPVSRDIL.METLLYEQLLEPL-..TMEVLG.VTDP......EEDLDPMED.FDPLEC..MEDS.DMLALRLACIGDEMDVSLRAPRLAQLSEVA.....MHSlgLAFIYDQTdDIRDVLTSFMDGFTTLKENiMRFWRSLNPGSQVS...R...EQVL---LALLLLLAAL.LSGGLHLLL...........
A0A091IU30_EGRGA/1-146               ...............msqtrriprhfvlssypngapeeetysnlrtipdtte------------.--------------..------.----......---------.--QMEF.nISLA.TQVGHQLALIGDEFNRTYHRKFEDTLLHLA.....-HG..VAISV--F.QTWNIIKSVIRSFGNILNN.NWTKRIIGYGSWIC...RlpfRCVCQKLVPAALLVAA-.---------fwwavnygl..
A0A2K5CLG5_AOTNA/1-154               ....................................................MSEVRPLSSDIL.METLLCEQFVHPL-..TMEVVG.GSDP......EEDLDPVE-.-DPLEC..MENS.DALVLQLACIADQMDVSLRARRLAQLYEVA.....MYSpgLAFILDRT.DIGDVLSGIVEVFANFQEDiVRLWRSLSSGSWVS...R...KQAV--LLALLALLLAM.FSGGLHLLL...........
A0A2Y9Q9J0_DELLE/213-273             .............................................fsephri------------.--------------..------.----......---------.------..----.------------------------------.....-AQ..LVFPYSHI.GLRDVLRSFMVAFTNLREN.RSLWSFLTLRDRVS...L...DSMT-------------.---------ltyipa.....
A0A093HL55_STRCA/13-146              ............................lssypsgapgeesysslltipdtt------------.--------------..------.----......---------.-QQMEF.nISTA.IQVGHQLAVIGDEFNRTYNRK----FEDTL.....LHL.aRGVAISVF.QTWNIIKSVIRSLGNLLSN.NWTKKIIGYGSWIC...RlpfRCVCQKLVPAALLVVAF.---------wwtinygl...
A0A6J0WRF9_ODOVR/93-241              ....................................................MYQARPLSRNLF.LYTFLQNHGPGFLDdqDSGLPG.V---......----TSILE.FHPVSP..YSDSpHYLAMQLASIADEMELRLLLPQFDEPFWMT.....TYS..LFFPYSHV.GLRDVLRSLMAAFTNLREN.RRLWSFLTLRDRVS...P...SLWP--ELALSLLVVAM.LSWG-----crlh.......
A0A7N5KDU2_AILME/133-281             ....................................................MSHTGPLSRNLF.LSTFLQEHGPEVL-..--EVPG.MTDL......VEYYDPGPS.PN----..SNNP.DDVAMRLAFIGDEMEVRWMLPRVGELPGMA.....MYS..LAFTYNQT.GLRGVLRSLVDGLTNLREN.VRIWSFLTFRNRVS...P...HPGRGLVLSLLLLLGLL.LGWGFRL--lq.........
L8HQS1_9CETA/93-216                  ....................................................MYQARPLSRNLF.LYTFLQNHGPGFLDdqDSGLPG.----......---VTSILE.FHPISP..YSDSpHYLAMQLASIADEMELRLLLPQFVEPFWMT.....MYS..LFFPYSHV.GLRDVLRSFMAAFTNLREN.RRLWSFLTL-----...-...-----------------.---------rdrg.......
A0A2K5J4Q7_COLAP/1-159               ....................................................MSGVRPISRDIL.METLLYEQLLEPL-..TMEVLG.VTDP......EEDLDPMED.FDPLEC..MEDS.DMLALRLACIGDEMDVSLRAPRLAQLSEVA.....MHSlgLAFIYDQTdDIRDVLRSFMDGFTTLKENiMRFWRSPNPGSRVS...R...EQVLLALLLLLALLLAL.LSGGLHLLL...........
A0A2K6FM79_PROCO/1-151               ....................................................MSEVRPVSTDLL.METFPFEHLLDPL-..ILEVLS.IMDN......EENPDPS--.----GC..LEDS.DEVALRLACIGDEMDLCLRSPRLAWLPGMT.....MHSlgLALSCDQP.VRWGVLGSLSDGFANLREYvARLWRSLSPRPWVC...P...APAWEQVLL-LLLVLLL.LGGGLHLLL...........
H0XAE7_OTOGA/1-146                   ....................................................MSAGRPVSMDHF.METFPFEQLLEPL-..TMEVLG.MTEP......---------.-NPMEC..LEDS.DQVALRLACIGDEMDLHLRSPRLAQLSRMT.....MHS..LGLSYNQT.DGQGVLRSVISGFTNLRENiAGFWRSLSRGPWVC...P...APAWEQVLLLLLLLVLL.LAGGLHLLL...........
A0A2U4C3H7_TURTR/1-130               ....................................................MYQARPLSRNLF.LYTFLQNHGPGFLDdqGEGLPG.MTNI......-LEFHPVS-.-----P.ySDGP.HYLAMQLASIADEMELRLLLPQFVEPIRMT.....V--..----YSHI.GLRDILRSFMVAFTNLREN.RSLWSFLTLRDRVS...L...DSMT-------------.---------ltyipa.....
A0A341AS40_NEOAA/1-143               ....................................................MYQARPLSRNLF.LYTFLQNHGPGFLDdqGEGLPG.VTNI......-------LE.FHPVSP.ySDGP.HYLAMQLASIADEMELRLLLPQFVEPIRMT.....V--..----YSHI.GLRDVLRSFMVAFTNLREN.RSLWSFLTLRDRVS...P...SPWPELALSLLLVVTLS.WGRRL----h..........
H0W025_CAVPO/1-158                   ....................................................MSEAKPVARDPL.METPLFEPPPGPLL..AEGALG.VTQPl....wAEDLSPPGD.TNLMEC..VEGS.SLVALRLACIGDEMDLRLRSPRLAQLPGRA.....VHS..LAITYSQM.GLWGVLGRLTLSLASLRDN.VWACGRPASRAWVS...P...RWTCRWLLPVLLLLLLL.LGTL-RL--llq........
A0A6J3GH50_SAPAP/1-139               ....................................................MSEVRPLSSDIL.METLLCEQFMDPL-..TMEVVGgGSDP......EEDLDPVE-.-DPLEC..MENS.DALALQLACIADQMDVSLRARRLAQLYEVA.....MYSpgLAVTLDQT.DIRDVLGGIVDVFANFQEDvVRLWRSLSSGSWVR...-...-----------------.---------alrflyvtc..
A0A2I0U3R3_LIMLA/64-207              ....................msrvprhfvlssypneapeeetysnlrtipdt------------.--------------..------.----......---------.TEQMEF.nISSA.TQVGHQLALIGDEFDRMYHRK----FEDTL.....LHL.aRGVAISVF.QTWNIIKSVIRSFGNTLNN.NWTKRIIGYGSWIC...KlpfRCVCQKLVPAALLVVAF.---------wwamnygll..
A0A2I0MK53_COLLI/19-146              ...................................gapeegtysnlqtipdt------------.--------------..------.----......---------.TEQMEF.nISSA.TQVGHQLALIGDEFNR-MYHRKLEDTLLHL.....AHG..VAISVF--.QTWNIIKSVIRSFGNILNN.NWTKRIFGYGSWIC...RlpfRCVCQKLVPAALLVVAF.---------wwavnygl...
A0A087R1N5_APTFO/1-146               .................msqtrriprhfvlssypngapeeetysnfrtiadt------------.--------------..------.----......---------.TEQMEF.nISSA.AQVGHQLALIGDEFNRMYHRK----FEDTL.....LHL.aRGVAISVF.QTWNIIKSVIRSFGNILNN.NWTKRIIGYGSWIC...RlpfRCVCQKLVPAALLVAA-.---------fwwavnygl..
A0A5F4W4K0_CALJA/122-275             ....................................................MSEVRPLSSDIF.METLLCEQFVDPL-..TMEVVG.GSDP......EEDLDPVE-.-DPLEC..MENS.DALALQLACIADQMDVSLRARRLAQLYEVA.....MYSpgLAFVLDRT.DIGDVLSGVVDVFANFQEDiVRLWRSLSSGSWVS...R...KQAV--LLALLALLLAM.FSGGLHLLL...........
A0A5E4BLD2_MARMO/1-150               ....................................................MSEARPVSRSLL.------RYRPGPLL..AAGASC.MTPPm....gEEVLRLGGN.LHLM--..VQGS.NQVALRLACIGDEMDLCFRGLQLAQLPGMA.....MHS..LALSYSQA.RVTGVLRSLTQGLASLREN.MWFWRPAAPSTRVP...P...ARACRELLPVLLLLGLL.LSRALYLRL...........
A0A455BBN3_PHYMC/1-143               ....................................................MYQARPLSRNLF.LYTFLQNHGPGFL-..--DDQG.EGLP......--GVTSILE.FHPVSP.ySDGP.HYLAMQLASIADEMELRPLLPQFVEPIRMT.....V--..----YSHI.GLRDVLRSFMVAFTNLREN.RSLWSFLTLRDRVS...P...SPWPELALSLLLAVTLS.WGRRL----h..........
A0A2K5LDM6_CERAT/1-155               ....................................................MSGVRPISRDTW.METLLYEQLLEPL-..TMEVLG.VTDP......EEDLDPMED.FDPLEC..MEDS.DMLALRLACIGDEMDVSLRAPRLAQLSEVA.....MHSlgLAFICDQTdDIRDVLRSFMDGFTTLRENiMRFWRSPNPRSWVS...H...EQ----VLLLLALLLAL.LSGGLHLLL...........
G1TZR9_RABIT/1-128                   ....................................................MSEVRPGSRDLF.QEALLDEQVPEPLL..TAEVPG.LTRP......VE----EGD.LDLMEC..LEGS.NQVALRLAYIGDEMDLHPRRYTSARLL-VP.....SYS..LAFTYSQT.GFTGVLGSVGLHLASLVEL.WSPWVRAWG-----...-...-----------------.---------apwsrfcls..
G1PFC4_MYOLU/1-80                    ....................................................MSQAGHLSRSLI.LCTFLQEHGLQAVE..DPGVTS.LLQY.....sPEPLGPRR-.-----A..L--P.HEVAMRLAFIGDELEVRWTLPRFAHVPWMA.....MY-..--------.-------------------.--------------...-...-----------------.---------...........
BIK_MOUSE/1-149                      ....................................................MSEARLMARDVI.-KTVPHDQVPQPPV..ASETPS.MKEP......------VRD.VDLMEC..VEGR.NQVALRLACIGDEMDLCLRSPRLVQLPGIA.....IHR..LAVTYSRT.GVRGIFRSLIRSLTNLREN.IWSWRVLTPGAWVS...P...DQDPGQLFPMVLLVFLL.LGGAWYLQL...........
A0A2R8VI69_MOUSE/1-105               ..................................................mf------------.--------------..------.----......---------.------..--TR.NQVALRLACIGDEMDLCLRSPRLVQLPGIA.....IHR..LAVTYSRT.GVRGIFRSLIRSLTNLREN.IWSWRVLTPGAWVS...P...DQDPGQLFPMVLLVFLL.LGGAWYLQL...........
A0A091PDK0_APAVI/1-146               .................msqtrriprhfvlssypngapeeethsnlrtipdt------------.--------------..------.----......---------.TEQMEF.nISSA.TQVGHQLALIGDEFNRMYHRKFEDTLLHL-.....AHR..VAISVFQT.--WNIIRSVIRSFGNTLNN.NWTKRIIGYGSWIC...RlpfRCVCQKLVPAALFV---.---------aafwwamnygl
A0A663MAW9_ATHCN/1-148               .................msqtrriprhfvvssypngapeeetysnlqtipdt------------.--------------..------.----......---------.TEQMEF.nISSA.TQVGHQLALIGDDFDRMYHRKMEDTLLHLA.....-RG..VAISVFQT.-WNNIIKSVLRSFGTIWNN.NWTKRIVGYGSWVWrlpC...SCLCQKLVPAALLLVAL.WW-------avtyglr....
A0A091T481_PHALP/1-147               .................msqtrriprhfvlssypsgapeeetysnlrtipdt------------.--------------..------.----......---------.TEQMEF.nISSA.TQVGHQLALIGDEFNRTYHRKFEDTLLHLA.....-HG..VAISV--F.QTWNVIKSVTKSFGNILNN.NWAKRIIGYGSWIC...RlpfRCVCQKLVPAALLVVAF.---------wwamnyglq..
A0A6P3HRX1_BISBI/1-147               ....................................................MYQARPLSRNLF.LYTFLQNHGPGFLDdqDSGLPG.----......---VTSILE.FHPISP..YSDSpHYLAMQLASIADEMELRLLLPQFVEPFWMT.....MYS..LFFPYSHV.GLRDVLRSFMAAFTNLREN.RRLWSFLTLRDRVS...P...SLWP--ELALSLLVVAM.LS-------wgcr.......
A0A091TTF0_PHORB/1-147               .................msqtrriprhfvlssypngapeeetysnlrtipdt------------.--------------..------.----......---------.TEQMEF.nISSA.AQVGRQLALIGDEFNRTYHRKFEDTLLHLA.....-HG..VAISVF--.QTWNIIKSVIRSFGNILNN.NWTKRIIGYGSWIG...RlpfSCVCQKLVPAALLLVAF.---------wwamnyglq..
A0A6J3GH52_SAPAP/1-155               ....................................................MSEVRPLSSDIL.METLLCEQFMDPL-..TMEVVGgGSDP......EEDLDPVE-.-DPLEC..MENS.DALALQLACIADQMDVSLRARRLAQLYEVA.....MYSpgLAVTLDQT.DIRDVLGGIVDVFANFQEDvVRLWRSLSSGSWVS...R...KQAV--LLALLALLLAT.FSGGLHLLL...........
A0A091FNN6_9AVES/13-146              .............................lssypngapeeetysnlqtipdt------------.--------------..------.----......---------.TEQMEF.nISSA.TQVGHQLALIGDEFNRMY-HRK---LEDTL.....LHL.aRGAAISVF.QTWNIFKSVIRSFGKILNN.NWTKRIIGCGSWIC...KlpfRCVCQKLVPAALLAVA-.---------fwwamnygl..
A0A2U3ZCW7_ODORO/1-147               ....................................................MSHTGPLSRNPS.WSTFLRERGPEVL-..--EVPG.MTDL......MEYYDPGPS.PNS---..--TN.SDVAMRLAFIGDEMEVRWMLPRVGEMPGMA.....MYS..LALTYNQT.GLRGVLRSFMDGLSNLRES.IRIWSFLTFRNRVP...P...NPGRGLVLSLLLLLVLL.LG-------wgpqlq.....
A0A6J2N6B9_9CHIR/1-144               ....................................................MSQGGPLSRNLI.LCTFLQEHSLQPVE..VADTAS.LLHF......--SPEPHGD.I-----..---Q.HEMAMRLASIGDELELRWMLPRVAQMPWMA.....VYS..LAFTYNQT.GLRGVLRSFMGGLTNLRGN.RRFWSFLTLRDRVS...P...GLGR--RLSLLLLLALL.LDWGLHV--lq.........
L9KP51_TUPCH/1-151                   ....................................................MSAARPLPADLL.LEPHLFEQLVEILS..TMEVPG.MTEP......TEGLAPAED.LDLLGC.lMEDR.DQVALRLACIGDEMDLRLRSPRLAQLPGMA.....MHSlgLAVTYNQT.GVRGVFRSLANSLGSLRQ-.--------IRTWVT...P...GQVCRQALPAMLLLLLLvLSGVLHLLL...........
F6RS78_HORSE/46-168                  ....................................................MSQVGPVSRDLF.LDAFLHERSPEAL-..--EVPG.MTEL......TES-SPDS-.------..-DNR.DSVAMRLAFIGDEMEVRWMLPHIAELPGVA.....VYS..LAFTYNQT.GLRGVFRSFMDGLTNLREN.IRFWSFLTRRDRVS...L...-----------------.---------rfhdl......
I3LVX0_ICTTR/1-106                   ...................................................m------------.--------------..------.----......---------.------..VQGS.HQVALRLACIGDEMDLCFQDLQLAQLPGMA.....MHS..LALSYSQA.RVTGVLRSLAQGLASLREN.MWFWRPAAPSTRVP...P...ARACRELLPVLLLLGLL.LSRALYLRL...........
A0A674KC62_TERCA/10-151              ....................................hfvlshdqngvavpne------------.--------------..------.--ES......QNRLSTVPDnTEQMAF.nISSA.TQVGHQLAVIGDEFNSTY-TRKLEDMLFHL.....AQG..MAVNVLKI.LHMHVWKSILKSFRSLLNN.GWTKRVVAYGSWIS...RlplKSMCQRLMPAALFVILF.---------wwtvsyglq..
H2QLU7_PANTR/1-159                   ....................................................MSEVRPLSRDIL.METLLYEQLLEPP-..TMEVLG.VTDS......EEDLDPMED.FDSLEC..MEGS.DALALRLACIGDEMDVSLRAPRLAQLSDVA.....MHSlgLAFIYDQTeDIRDVLRSFMDGFTTLKENiMRFWRSPNPGSWVS...R...EQVLLALLLLLALLLPL.LSGGLHLLL...........
A0A2Y9Q3W1_DELLE/212-265             .............................................rfsephr------------.--------------..------.----......---------.------..----.------------------------------.....IAQ..LVFPYSHI.GLRDVLRSFMVAFTNLREN.RSLWSFLTLR----...-...-----------------.---------dresppc....
A0A6J2ACU8_ACIJB/1-148               ....................................................MSHAGPLSRNVF.LSTFLQEHGPEVL-..--DVPG.MTDL......VEYYDPGPS.PNS---..-NSP.DDVAMRLAFIGDEMEVRWMMPRVGELPGMA.....VYS..LAFTYNQT.GLRGVLRSLMDGLANLREN.IRIWGFLTLRNRVS...P...NSGRGLALSLLLLV-LL.LGWGLHLL-q..........
A0A6P6CWH7_PTEVA/1-140               ..........mplsrnlilctflqehglqaqsppgmtnllqhynphpygdip------------.--------------..------.----......---------.------..----.HEMAMRLAFIGDEMEVRWTLPRIAELPWMA.....VYS..LAFTY-QT.GLRGVLRSFIDGLTNLRGN.RRFWSFLTLRDRVS...P...TRGR--KLSLLLLLVLL.LDWGLHLL-q..........
A0A663EYV3_AQUCH/18-147              ..................................ngapeeeiysnlrtipdt------------.--------------..------.----......---------.TEQMEF.nISSA.TQVGHQLALIGDEFNRTYH-RKLEDTLLHL.....AHG..VAI--SVF.QTWNIIKSVIRSFGNILNN.NWTKRIIGYGSWIC...RlpfRCVCQKLVPAALLVIAF.---------wwamnyglq..
A0A099Z8J2_TINGU/1-146               .................msqtrriprhfvvssyprqapgeesysslltipdt------------.--------------..------.----......---------.TQQMEF.nISSA.VQVGHQLALIGDDFN-RLYNRKFEDALLHL.....AHR..VAISVFQT.--WNIIKSVIRSFGNLWNN.NWTKRIIGYASWVC...RlpfRCLCQKLVPAAVLVVAF.---------wwtinygl...
G1S1X2_NOMLE/1-159                   ....................................................MSEVRPISRDIL.MESLLYEQLLEPP-..TMEVLG.VTDP......EEDLDPMED.FDPLQC..MEGS.DALAPRLACIGDEMDVSLRAPRLAQLSEVA.....MHSlgLAFIYDQTeDIRDVLRSFMDGFTTFKENiIRLWRSPNPGSRVS...R...EQMLLVLLVLLLLLLPL.LSGGLYLL-n..........
A0A673V4V4_SURSU/9-156               ....................................................MSHAGPLSRDVF.LSTFLQEHGPEVL-..--DVPG.VTDL......VEYYDPGPS.PN----..SNSP.DDVAMRLAFIGDEMEVRWMVPRVGELPGMA.....LYS..LAFTYNQT.GLRGVLRSLMDGLASLREN.IRVWSFLTLRNRVS...P...NAGRGLALSLLLLVLLL.SWGLHHL--q..........
H2P4N6_PONAB/1-125                   ....................................................MSEVRPISRDIL.METLLYEQLLEPP-..TMEVLG.VTDS......EEDLDPMED.FSPLEC..MEGS.DALALRLACIGDEMDVSLRAPRRAQLPEVA.....MHSlgLAFIYDQTeDIRDVLRSFTDGFTTLKENiMRFWSSL-------...-...-----------------.---------...........
A0A3Q7TH07_URSAR/1-149               ....................................................MSHTGPLSRNLF.LSTFLQEHGPEVL-..--EVPG.MTDL......VEYYDPGPS.PN----..SNNP.DDVAMRLAFIGDEMEVRWMLPRVGELPGMA.....MYS..LAFTYNQT.GLRGVLRSLMDGLTNLREN.IRIWSFLTFRNRVS...P...HPGRRLVLSLLLLLGLL.LGWGFRL--lq.........
A0A2U4C3L6_TURTR/18-138              ....................................................MYQARPLSRNLF.LYTFLQNHGPGFLDdqGEGLPG.MTNI......-LEFHPVS-.-----P.ySDGP.HYLAMQLASIADEMELRLLLPQFVEPIRMT.....V--..----YSHI.GLRDILRSFMVAFTNLREN.RSLWSFLTLR----...-...-----------------.---------drespp.....
A0A2K6MCW0_RHIBE/1-156               ....................................................MSGVRPVSRDIL.METLLYEQLLEPL-..TMEVLG.VTDP......EEDLDPMED.FDPLEC..MEDS.DMLALRLACIGDEMDVSLRAPRLAQLSEVA.....MHSlgLAFIYDQTdDIRDVLTSFMDGFTTLKENiMRFWRSLNPGSQVS...R...EQVL---LALLLLLAAL.LSGGLHLLL...........
G5BM80_HETGA/1-158                   ....................................................MSEARPVTRDLL.METLLYEPLPGPLL..ATGALA.VMHPf....rGEDLSPPGD.TDLVGC..LEGS.SLMALRLACIGDEMDLRLRAPRLAQLPGRA.....VHS..LAITYSQM.GLWGVLRSLTPGLTSLRD-.MWPWGHLAPHAWVS...P...GWACRQLLPVVLLVLLLgILRLLLQ--gg.........
A0A1V4K4Z8_PATFA/38-167              ..................................ngapeeetysnlqtipdt------------.--------------..------.----......---------.TEQMEF.nISSA.TQVGHQLALIGDEFNR-MYHRKLEDTLLHL.....AHG..VAISVF--.QTWNIIKSVIRSFGNILNN.NWTKRIFGYGSWIC...RlpfRCVCQKLVPAALLVVAF.---------wwamnyglq..
A0A2Y9KMR9_ENHLU/1-149               ....................................................MSHTGPLPRNLF.LSTFLQEHGPEVL-..--EVPG.MTDL......VEYYDPGPS.PNS---..-SNP.DDVAMRLAFIGDEMEVRWTLPRIGELPGMA.....VHS..LAFTYNQM.GLRGVLRSFVDGLTNLREH.IRIWSFLTFRNRVS...P...NPGRGLVLSLLLLVVLL.LGWGLQ---vlq........
A0A452H552_9SAUR/10-151              ...............................hfvlshdqngvavpneesqnr------------.--------------..------.----......---LLTVADtTEQMAF.nISSA.TQVGHQLAVIGDEFNST-YSRKLEDMLFHL.....AQG..MAVNVLKI.LHMHVWKSIIKSFRSLLNN.GWTKRVVAYGSWIS...RlplKSMCQRLMPAALFVILF.---------wwtvsyglq..
A0A452QUG1_URSAM/38-146              ..............................................tgplcn------------.--------------..------.----......---------.------..--NP.DDVAMRLAFIGDEMEVRWMLPRVGELPGMA.....MYS..LAFTYNQT.GLRGVLRSLMDGLTNLREN.IRIWSFLTFRNRVS...P...HPGRRLVLSLLLLLGLL.LGWGFRL--lq.........
A0A093DNA9_9AVES/1-146               .................msqtrriprhfvlssypngapeeetysnlqtipdt------------.--------------..------.----......---------.TEQMEF.nISSA.TQVGHQLALIGDEFNRTYHRKFEDTLLHLA.....-HG..VAISVF--.QTWNTIKSVIRSFGNILNN.NWTKRIIGYGSWIC...RlpfRCVCQKLVPAALLVVAF.---------wwamnygl...
A0A093R0X3_PHACA/1-146               .................msqtrriprhfvlssypngapeeetysnlqtipdt------------.--------------..------.----......---------.TEQMEF.nISSA.TQVGHQLALIGDEFNRTYHRKFEDTLLHLA.....-HG..VAISVF--.QTWNIIKSVLRSFGNILNN.NWTKRIVGYGSWIC...RlpfRCVCQKLVPAALLVAA-.---------fwwamnygl..
A0A091HF67_BUCRH/6-147               ......................ripgpsvlssytngapeeeiysnrqtipdt------------.--------------..------.----......---------.TEQMEF.nISSA.TQVGHQLALIGDEFNRTYYRK----FEDTL.....LHL.tHVVALSVF.QTWDIIKSVIRSFGNVLNN.NWTKRIIGYGSWIC...RlpfQCVCQNLVPAALLVVAF.---------wwamnyglq..
A0A341AUS9_NEOAA/1-130               ....................................................MYQARPLSRNLF.LYTFLQNHGPGFLDdqGEGLPG.VTNI......-------LE.FHPVSP.ySDGP.HYLAMQLASIADEMELRLLLPQFVEPIRMT.....V--..----YSHI.GLRDVLRSFMVAFTNLREN.RSLWSFLTLRDRVS...L...DSMT-------------.---------ltyipa.....
A0A6P5BEU3_BOSIN/1-147               ....................................................MYQARPLSRNLF.LYTFLQNHGPGFLDdqDSGLPG.----......---VTSILE.FHPISP..YSDSpHYLAMQLASIADEMELRLLLPQFVEPFWMT.....MYS..LFFPYSHV.GLRDVLRSFMAAFTNLREN.RRLWSFLTLRDRVS...P...SLWP--ELALSLLVVAM.LS-------wgcr.......
#=GC SS_cons                         .................XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------.--------------..------.----......---------.XXXXXX.X--TT.S-HHHHHHHHHHHHHHH--XXXXXXXXXXX.....XXX..XXXXXX--.XXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXX...XXXXXXXXXXXXXXXXXXXXX.---------XXXXXXXXX..
#=GC seq_cons                        ....................................................M.tst.hsts.....s...p...t.......th.s......................c.hph..hpsu.splAhpLAhIGDEM-lphph.phspL.thA.....hau..LAhsYsph.slRsVLRShhcuFsNL+EN.hhhWphlshtshVs.......ppsh..llshhLLlhhh..........h..........
//
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