#=GF ID dATP-dGTP_PPHyd
#=GF AC PF04447.18
#=GF DE dATP/dGTP pyrophosphohydrolase
#=GF PI DUF550;
#=GF AU Kerrison ND;0000-0002-1471-953X
#=GF SE DOMO:DM04177;
#=GF GA 23.00 23.00;
#=GF TC 23.10 23.00;
#=GF NC 22.80 22.90;
#=GF BM hmmbuild --amino HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 --cpu 8 -Z 90746521 HMM pfamseq
#=GF TP Domain
#=GF CL CL0231
#=GF RN [1]
#=GF RM 33926954
#=GF RT A widespread pathway for substitution of adenine by
#=GF RT diaminopurine in phage genomes.
#=GF RA Zhou Y, Xu X, Wei Y, Cheng Y, Guo Y, Khudyakov I, Liu F, He P,
#=GF RA Song Z, Li Z, Gao Y, Ang EL, Zhao H, Zhang Y, Zhao S;
#=GF RL Science. 2021;372:512-516.
#=GF DR INTERPRO; IPR007538;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This domain is found in phage proteins, such as A0A2H5BHG5 from
#=GF CC Acinetobacter phage SH-Ab 15497, which are associated with PurZ,
#=GF CC an enzyme that catalyses the synthesis of diaminopurine (Z), a
#=GF CC DNA modification that gives phages an advantage for evading host
#=GF CC restriction enzymes activity [1]. This domain has dATP and dGTP
#=GF CC pyrophosphohydrolase activity; it catalyses the hydrolysis of
#=GF CC dATP/dGTP to pyrophosphate and dAMP/dGMP, respectively, with
#=GF CC little or no activities for NTPs and pyrimidine dNTPs. It is
#=GF CC suggested that enzymes containing this domain supply dGMP as the
#=GF CC substrate for PurZ, elevating dZTP level to promote Z
#=GF CC incorporation [1].
#=GF SQ 130
#=GS K7PKG8_9CAUD/100-147 AC K7PKG8.1
#=GS B7LBR2_ECO55/42-138 AC B7LBR2.1
#=GS A0AAF0CHZ1_9CAUD/181-276 AC A0AAF0CHZ1.1
#=GS A0A6C2YMJ7_9BACT/43-144 AC A0A6C2YMJ7.1
#=GS A0A482MGA0_9CAUD/100-196 AC A0A482MGA0.1
#=GS A0A7G8LGB8_9CAUD/10-106 AC A0A7G8LGB8.1
#=GS A0AAE3J1G8_9RHOB/7-107 AC A0AAE3J1G8.1
#=GS A0AAE7VL67_9CAUD/215-312 AC A0AAE7VL67.1
#=GS A0A0J9EDS5_9RHOB/8-117 AC A0A0J9EDS5.1
#=GS A0A7D5FU59_9CAUD/47-139 AC A0A7D5FU59.1
#=GS A0A1V1PPM7_9PROT/12-104 AC A0A1V1PPM7.1
#=GS A0A3M6R0X6_9BURK/34-132 AC A0A3M6R0X6.1
#=GS A0A071M269_9ENTR/63-159 AC A0A071M269.1
#=GS A0AA51N680_9CAUD/63-159 AC A0AA51N680.1
#=GS A0A0H3CG24_ENTCC/16-108 AC A0A0H3CG24.1
#=GS A0A3Q9R907_9CAUD/148-245 AC A0A3Q9R907.1
#=GS A0A385DX16_9CAUD/10-107 AC A0A385DX16.1
#=GS A0A1R3Y5Q8_9CAUD/104-200 AC A0A1R3Y5Q8.1
#=GS A0A076G6W7_9CAUD/137-235 AC A0A076G6W7.1
#=GS A0A0Q4MFJ2_9GAMM/18-113 AC A0A0Q4MFJ2.1
#=GS A0A1B0YZX5_9CAUD/67-165 AC A0A1B0YZX5.1
#=GS A0A1E3H797_9HYPH/9-106 AC A0A1E3H797.1
#=GS D5RTI5_9PROT/59-160 AC D5RTI5.1
#=GS A0A6I6MMZ5_9CAUL/5-97 AC A0A6I6MMZ5.1
#=GS A0A944DAZ8_DENI1/46-141 AC A0A944DAZ8.1
#=GS A0AAE3KB49_9GAMM/18-86 AC A0AAE3KB49.1
#=GS A0A977J4B2_9CAUD/91-187 AC A0A977J4B2.1
#=GS A0A916SH59_9HYPH/193-290 AC A0A916SH59.1
#=GS A0A916XGL7_9HYPH/70-167 AC A0A916XGL7.1
#=GS A0A7L8ZHG6_9CAUD/42-138 AC A0A7L8ZHG6.1
#=GS A0A9E7E3D6_9CAUD/63-159 AC A0A9E7E3D6.1
#=GS A0A6N4T6B0_9BURK/196-292 AC A0A6N4T6B0.1
#=GS A0A4S4B6W9_9RHOO/21-117 AC A0A4S4B6W9.1
#=GS C6XNE6_HIRBI/5-96 AC C6XNE6.1
#=GS A0AAJ2E3T4_9BURK/150-239 AC A0AAJ2E3T4.1
#=GS A0AAJ1ZZC2_9BURK/182-271 AC A0AAJ1ZZC2.1
#=GS A0A1G8XG83_9GAMM/130-227 AC A0A1G8XG83.1
#=GS A0A6S7EIQ0_9BURK/200-297 AC A0A6S7EIQ0.1
#=GS A0A1E3H5Q2_9HYPH/1-51 AC A0A1E3H5Q2.1
#=GS A0A2T5HFN3_9PSED/124-222 AC A0A2T5HFN3.1
#=GS A6WZ32_BRUA4/75-173 AC A6WZ32.1
#=GS A0A515MKH4_9CAUD/10-108 AC A0A515MKH4.1
#=GS R4JG80_9CAUD/183-280 AC R4JG80.1
#=GS A0A2K8HR09_9CAUD/58-156 AC A0A2K8HR09.1
#=GS A0A1V0DZ25_9CAUD/47-142 AC A0A1V0DZ25.1
#=GS DGTPH_BPS2L/8-100 AC A0A7U3TBV3.1
#=GS A0AA43HV32_9BACT/9-124 AC A0AA43HV32.1
#=GS A0A7L7SSX8_9CAUD/48-144 AC A0A7L7SSX8.1
#=GS A0A285PHQ7_9HYPH/61-157 AC A0A285PHQ7.1
#=GS A0A977TFK3_9CAUD/149-245 AC A0A977TFK3.1
#=GS A0A193GZ33_9CAUD/89-185 AC A0A193GZ33.1
#=GS A0A482J4Z5_9CAUD/51-147 AC A0A482J4Z5.1
#=GS A0A5J6T7U2_9CAUD/98-194 AC A0A5J6T7U2.1
#=GS A0A1B0WMR2_9CAUD/6-107 AC A0A1B0WMR2.1
#=GS A0A0Q5TVG7_9BACT/101-196 AC A0A0Q5TVG7.1
#=GS A0A3D9HYV3_9PROT/7-102 AC A0A3D9HYV3.1
#=GS A0A495JW60_9ACTN/189-286 AC A0A495JW60.1
#=GS A0A2H4PF37_9CAUD/10-107 AC A0A2H4PF37.1
#=GS A0A8J7MTL9_9RHOB/7-119 AC A0A8J7MTL9.1
#=GS A0A0H3GP91_KLEPH/103-199 AC A0A0H3GP91.1
#=GS A0AAE8BYW8_9CAUD/98-190 AC A0AAE8BYW8.1
#=GS M4R1A4_9CAUD/77-189 AC M4R1A4.1
#=GS A0A6M0H4G1_9CLOT/33-121 AC A0A6M0H4G1.1
#=GS A1B0N4_PARDP/14-110 AC A1B0N4.1
#=GS A0A6C2YVV4_9BACT/57-158 AC A0A6C2YVV4.1
#=GS A0A0N7CFQ2_BPP22/83-179 AC A0A0N7CFQ2.1
#=GS A0A0M4RTV1_9CAUD/90-186 AC A0A0M4RTV1.1
#=GS A0AAE3KB49_9GAMM/108-192 AC A0AAE3KB49.1
#=GS A0A8T8IUZ5_9CAUD/16-108 AC A0A8T8IUZ5.1
#=GS A0A643FG54_IDEDE/21-117 AC A0A643FG54.1
#=GS A0A9E7U3J9_9CAUD/94-186 AC A0A9E7U3J9.1
#=GS H8YJ28_9CAUD/11-88 AC H8YJ28.1
#=GS K7PGV7_9CAUD/165-261 AC K7PGV7.1
#=GS A0A143WUV3_9FIRM/42-125 AC A0A143WUV3.1
#=GS A0A348FZC1_9HYPH/127-222 AC A0A348FZC1.1
#=GS A0A5Q2F6E7_9CAUD/42-138 AC A0A5Q2F6E7.1
#=GS H2BD43_9CAUD/7-105 AC H2BD43.1
#=GS A0A7S6R922_9CAUD/99-191 AC A0A7S6R922.1
#=GS A0A142XS31_9BACT/21-129 AC A0A142XS31.1
#=GS A0AA43RQR6_9BACT/4-102 AC A0AA43RQR6.1
#=GS A0A3B8DJD0_9CAUD/149-244 AC A0A3B8DJD0.1
#=GS A0A261UTP6_9BORD/54-152 AC A0A261UTP6.1
#=GS A0A2I7QIB2_9CAUD/11-88 AC A0A2I7QIB2.1
#=GS I0KCT3_9BACT/51-149 AC I0KCT3.1
#=GS A0A482MEY7_9CAUD/63-159 AC A0A482MEY7.1
#=GS A0A0N7CFK1_BPP22/83-179 AC A0A0N7CFK1.1
#=GS A0A345YFA3_9SPHN/142-236 AC A0A345YFA3.1
#=GS A0A4R7BD99_9NEIS/76-172 AC A0A4R7BD99.1
#=GS A0A1Y0T0I0_9CAUD/51-152 AC A0A1Y0T0I0.1
#=GS A0A7J5WS58_9ACTN/99-191 AC A0A7J5WS58.1
#=GS A0A9X9JTS0_9CAUD/98-190 AC A0A9X9JTS0.1
#=GS A0A1M4VVR9_9BACT/5-105 AC A0A1M4VVR9.1
#=GS A0AAE9Y9V8_9CAUD/99-191 AC A0AAE9Y9V8.1
#=GS A0A9E7M7E6_9CAUD/149-245 AC A0A9E7M7E6.1
#=GS A0A976N0M3_9CAUD/99-167 AC A0A976N0M3.1
#=GS A0A6C2YPZ7_9BACT/54-155 AC A0A6C2YPZ7.1
#=GS A0A6V8KBI2_9ACTN/106-202 AC A0A6V8KBI2.1
#=GS A0AA49B4B0_9CAUD/11-88 AC A0AA49B4B0.1
#=GS A0A514DFW6_9CAUD/75-172 AC A0A514DFW6.1
#=GS A0AAE7SPB7_9CAUD/165-260 AC A0AAE7SPB7.1
#=GS Q8HAI3_BPST6/139-235 AC Q8HAI3.1
#=GS A0A1V0DYC4_9CAUD/9-86 AC A0A1V0DYC4.1
#=GS K9L979_BPK36/98-190 AC K9L979.1
#=GS A0A482IL99_9CAUD/63-159 AC A0A482IL99.1
#=GS I6S1L7_9CAUD/139-235 AC I6S1L7.1
#=GS A0A938YGA7_9ACTN/101-202 AC A0A938YGA7.1
#=GS A0A916NC18_9BACT/69-167 AC A0A916NC18.1
#=GS A0A5Q2F7D3_9CAUD/58-156 AC A0A5Q2F7D3.1
#=GS A0A873WJ38_9CAUD/147-247 AC A0A873WJ38.1
#=GS A0A916YIZ0_9SPHN/155-227 AC A0A916YIZ0.1
#=GS A0A1H0Q0B4_9ACTN/25-121 AC A0A1H0Q0B4.1
#=GS A0A3G3M710_9CAUD/42-138 AC A0A3G3M710.1
#=GS VEAA_BPP22/83-179 AC Q03544.1
#=GS DGTPH_BPSHA/166-259 AC A0A2H5BHG5.1
#=GS A0A127EUZ2_9HYPH/7-114 AC A0A127EUZ2.1
#=GS DGTPH_BPPMB/149-243 AC A0A2L0V161.1
#=GS A0A977TG73_9CAUD/91-187 AC A0A977TG73.1
#=GS A0A976XLA7_9CAUD/145-241 AC A0A976XLA7.1
#=GS A0A1G7ND77_9GAMM/124-222 AC A0A1G7ND77.1
#=GS A0A0H2V7N6_ECOL6/42-138 AC A0A0H2V7N6.1
#=GS A0A1H0WNU9_9HYPH/8-107 AC A0A1H0WNU9.1
#=GS A0A9Y1YYY6_9CAUD/99-191 AC A0A9Y1YYY6.1
#=GS A0A976N0M3_9CAUD/6-88 AC A0A976N0M3.1
#=GS A0A7C9BV39_9BACT/55-151 AC A0A7C9BV39.1
#=GS A0A1G6UL80_9ACTN/97-195 AC A0A1G6UL80.1
#=GS A0AA36QK29_9CAUD/46-144 AC A0AA36QK29.1
#=GS A0A2Z2FBB9_9CAUD/168-264 AC A0A2Z2FBB9.1
#=GS A0A7G8LPG0_9CAUD/6-82 AC A0A7G8LPG0.1
#=GS A0A653FV81_9CAUD/42-138 AC A0A653FV81.1
#=GS A0A9X1JZS4_9RHOB/97-194 AC A0A9X1JZS4.1
K7PKG8_9CAUD/100-147 .........................................dqenedialtvgkl--------------...--....-.-.--.--...-.--...R...V...E-....L.E....A........A.A.....E.......P.D.....D....L......S....EWADMQFLLWDAQRR.L....--.........-----....-.--...--------------------.--------.---rslp........................
B7LBR2_ECO55/42-138 .......................................................IRHEHAKWSDSTFG...CV....G.P.IG.PL...K.HL...S...K...EA....L.E....A........A.A.....E.......P.D.....D....L......S....EWADMQFLLWDAQRR.A....GI.........SDAEI....T.AA...MENKLKINMERQWPEPKDGE.PRLHIKEP.GN-s...........................
A0AAF0CHZ1_9CAUD/181-276 ......................................................v-RIEHANWSQETFG...AA....G.P.IG.PL...K.HL...A...K...EA....I.E....A........A.E.....N.......P.G.....D....L......F....EWADMQFLLWDAQRR.A....GI.........TDEQI....T.KA...MIEKLAVNKSRKWPEPKYGE.PRHHIKDS.AE-............................
A0A6C2YMJ7_9BACT/43-144 ..................................................msetc-----WEWSQETFGtaeQR....G.P.KG.AL...L.HL...E...K...EA....R.E...aV........E.A.....I.......G.T.....D....Nl....tE....ELADCQILIWDAARR.A....GL.........GPVEL....L.HA...VRQKLEKNMARQWPMPTTDL.PVEHIRE-.---gsk.........................
A0A482MGA0_9CAUD/100-196 ......................................................v-RREHAEWSQATFG...NV....G.P.VG.PL...K.HL...S...K...EA....L.E....A........A.S.....E.......P.G.....D....L......S....EWADMQFLLWDAQRR.A....GI.........TDEQI....T.QA...MIEKLAVNKQRSWPEPKDGE.PRLHINEQ.P--al..........................
A0A7G8LGB8_9CAUD/10-106 ..................................................larqr------AFSLRTFG..pGA....R.T.NG.VI...D.HI...T...K...EL....D.E....V........R.K.....A.......P.T.....D....L......S....EWADVIILAFDGAWR.S....GA.........EPQQI....I.DA...IVAKQTRNEARVWPDWRTQD.PDKAIEHD.---rgp.........................
A0AAE3J1G8_9RHOB/7-107 .....................................................la--ARHAEWSQATFGadnER....D.Y.TG.PL...N.HL...E...K...EI....G.E....I........R.L.....A.......P.A.....D....G......S....EWADAFLLLLDAARR.A....GF.........SATDL....L.QE...AEDKLVINIKRKWQEPNEDG.SVEHVRNE.---eksd........................
A0AAE7VL67_9CAUD/215-312 .....................................................yl--RRQWEWSLRTFG..pGF....R.T.AG.IL...Q.HI...R...K...EL....G.E....V........E.K.....E.......P.H.....D....L......M....EWLDIIILAFDGYWR.H....GG.........SPERA....I.AL...LQKKQDKNFARNWPDWRTLG.EDKAIEHD.---rsg.........................
A0A0J9EDS5_9RHOB/8-117 ..................................................ltrqm------AFSRATYG..pGE....R.R.KG.VC...D.HI...R...K...EI...eK.E....I........L.K.....D.......G.V.....DaaeaA......T....EFVDLVLLSLDGLWR.AleasGV.........EWERIpyvaT.QM...ITAKQGRNEQRVWPDWRTMS.ADKAIEHD.---rtv.........................
A0A7D5FU59_9CAUD/47-139 ......................................................v-RAQHAEWSDQTFGavdKV....G.G.VG.CL...K.HL...A...K...EA....I.E....A........A.E.....N.......P.C.....D....L......S....EWADIQLLLWDAMRR.E....E-.........-SQTI....S.RR...LRKSLKSTKAI-PPEPKDGE.PRHHIK--.---i...........................
A0A1V1PPM7_9PROT/12-104 ...................................................tsas----IAQWGAETFG...EV....A.D.LT.VLtqrA.RI...E...F...EE....L.E....H........A.V.....R.......A.G.....Dv..dE......Ig..rEAADVMILLH---RL.V....GL.........VGKDL....A.SE...VDAKMQINRARRWR------.--------.---lsgdgvgqh...................
A0A3M6R0X6_9BURK/34-132 ....................................................hla---RQAEFSARTFG..pGQ....R.T.QG.VC...D.HI...R...K...EL....R.E....I........E.A.....A.......P.D.....D....L......S....EWIDVAILALDGAWR.I....GA.........TPTEI....I.AA...MVAKQTKNEGRRWPDWHTAD.PSKAIEHD.---rgde........................
A0A071M269_9ENTR/63-159 ......................................................v-RLEHAQWSQATFG...NV....G.P.VG.PL...K.HL...S...K...EA....M.E....A........A.A.....K.......P.N.....D....L......S....EWADMQFLLWDAQRR.A....GI.........TDEQI....T.QA...MIEKLEVNKARQWPEPKDGE.PRLHIKEQ.S--qp..........................
A0AA51N680_9CAUD/63-159 ......................................................v-RREHAEWSKATFG...NV....G.P.VG.PL...N.HL...S...K...EA....L.E....A........A.A.....E.......P.G.....D....L......S....EWADMQFLLWDAQHR.A....GI.........TDEQI....T.QA...MIDKLAVNKQRSWPEPKDGE.PRLHIKEQ.P--ap..........................
A0A0H3CG24_ENTCC/16-108 .......................................................IRRRHAEWSEQTFG...NV....G.P.IG.PL...K.HL...S...K...EA....L.E....A........A.A.....D.......P.G.....D....L......S....EWADLQFLLWDAQRR.A....GI.........TDEQI....T.AA...LEEKLKVNMARQWPEPKDGE.PRLHIK--.---a...........................
A0A3Q9R907_9CAUD/148-245 .......................................................LRAQHAAWSQAQFG...DV....S.A.VG.PA...K.HL...A...K...EA....T.E....V........A.A.....D.......P.L.....D....P......I....EHADCWMLLWDMQRR.A....GI.........SDAQL....A.DA...IREKLAINQARRWPAPREGE.AREHDRA-.---dqped.......................
A0A385DX16_9CAUD/10-107 ....................................................hia---RQREFSLRTFG..pGL....R.T.EG.VI...D.HI...A...K...EL....D.E....I........R.G.....A.......P.T.....D....L......S....EWADVIILAFDGAQR.T....GA.........DPQAI....L.DA...IVAKQTKNEDRQWPDWRTQE.PGKAIEHV.---rdh.........................
A0A1R3Y5Q8_9CAUD/104-200 .......................................................IRRKHAEWSDKTFG...DV....G.P.VG.PL...K.HL...S...K...EA....L.E....A........A.A.....D.......P.S.....D....P......L....EWADMQFLLWDAQRR.M....GI.........SDEFI....T.RA...MIEKLEINKSLQWPEPKDGE.PRLHIKEQ.PES............................
A0A076G6W7_9CAUD/137-235 ....................................................yye---RQIGWSRETFG..pAL....R.T.GG.II...D.HI...R...K...EL....R.E....I........E.Q.....E.......P.H.....D....L......S....EWVDVVILAMDGFWR.H....GG.........KAPDL....F.PA...LLAKQQKNMARVWPDWRTMS.EDSAIEHD.---rshd........................
A0A0Q4MFJ2_9GAMM/18-113 .......................................................IRARHAEWSQKTFG...DV....G.P.IG.PL...K.HL...S...A...EA....L.E....A........A.E.....K.......V.D.....D....L......S....EWADMQFLLWDAQRR.A....GI.........SDGEI....I.SA...MEEKLKVNMARNWPEPKDGE.PRMHIKDE.AE-............................
A0A1B0YZX5_9CAUD/67-165 ..................................................hlerq-----RRFSERTFG..pGS....R.A.AG.VI...D.HI...R...K...EL....R.E....I........E.E.....A.......P.G.....D....L......A....EWIDVVILALDGAWR.T....GA.........TPAQI....I.DA...LVAKQTKNEARTWPDWRSAP.SDKAIEHDrAD-d...........................
A0A1E3H797_9HYPH/9-106 .................................................hlhrqr------AFSERTFG..pGP....R.T.AG.VC...D.HI...R...K...EL....A.E....I........E.A.....D.......P.A.....D....A......K....EWIDVILLALDGAWR.A....GL.........TPEGI....A.GG...ILAKQTINEGRTWPDWRTAP.ADKAIEH-.---vrgg........................
D5RTI5_9PROT/59-160 .......................................................IRAEHAAWSDATFGrppAI....G.P.LG.PL...K.HL...A...K...EA....L.E....A........A.A.....A.......P.H.....A....L......E....EWADLQFLLWDAQRR.A....GI.........TDDQV....V.AA...MRQKLAVNKARHWPAPQDGE.PREHVKP-.---aggadd......................
A0A6I6MMZ5_9CAUL/5-97 ..................................................tsasi-----VQWGAETFG...EV....S.D.FA.VL...TqRA...R...A...EF....E.E....L........D.A.....Av.....rA.G.....D....Cd....eIg..rEAADVVILLH---RL.V....GL.........IGKDL....A.DE...VDAKMNVNRNRQWR------.--------.---lsgdgvgqh...................
A0A944DAZ8_DENI1/46-141 ..................................................lhrqk------AFSLEAFG..pGI....R.T.QG.VC...D.HI...R...K...EL....L.E....I........E.A.....N.......P.E.....D....I......M....EWIDVVLLALDGAWR.C....GI.........RPEWI....A.YC...LDDKQTINESRTWPDWRTAD.PGKAIEH-.---vrg.........................
A0AAE3KB49_9GAMM/18-86 ..................................................hlerq-----RAFSEETFG..pGA....R.T.RG.LV...D.HI...R...K...EI....I.E....V........A.D.....A.......P.D.....D....L......V....EWIDLALLFLDGAWR.A....GL.........SAAEV....-.--...--------------------.--------.---llllg.......................
A0A977J4B2_9CAUD/91-187 ......................................................v-RREHAEWSDKTFG...DV....G.P.VG.PL...K.HL...S...K...EA....L.E....T........A.A.....E.......P.D.....D....L......S....EWADMQFLLWDAQRR.A....GI.........SDEQI....T.LA...MVEKLAVNKKREWPEPKDGE.PRLHIKEQ.P--ap..........................
A0A916SH59_9HYPH/193-290 ....................................................yya---RQIEWSRNTFG..pGT....R.T.AG.VI...D.HI...R...K...EL....I.E....I........E.T.....E.......P.T.....D....L......S....EWIDVVILAMDGFWR.H....GG.........SAKDL....M.PR...LLAKQRKNFARKWPDWRTMS.EDEAIEHD.---rsg.........................
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I0KCT3_9BACT/51-149 ...................................................veak----RSAWARATFP...GT....T.P.LS.SL...R.HL...E...R...EI....E.E....I........E.A.....Di....vaG.K.....D....P.....tV....EYADALSMLLDSAGQ.A....GI.........GPRAL....I.DA...MHAKLLINQTRDWTQNPDGS.--------.---yahiepqps...................
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A0A1M4VVR9_9BACT/5-105 ...................................................qfet----ITKWQDRVFT...KA....T.P.LS.CI...N.HL...E...E...EV....K.E....L........K.T.....D.......V.E.....Q....G......KysydEIADCFLLLFAVCNK.C....GL.........EYEDV....V.AA...IDAKMQVNYKRQWGQANEKG.YVKHVVR-.---peeg........................
A0AAE9Y9V8_9CAUD/99-191 .......................................................IRAQHAEWSDRQFG...NV....G.P.VG.PL...K.HL...A...K...EA....I.E....A........A.E.....A.......P.D.....D....I......S....EFADILMLVWDATRR.A....GF.........SDEQL....A.EA...VAEKLERNKRRAWGEVKDGE.PCHHVK--.---n...........................
A0A9E7M7E6_9CAUD/149-245 ......................................................v-RSAHAEWSQATFG...NV....G.P.VG.PL...K.HL...S...K...EA....L.E....A........A.S.....E.......P.G.....D....L......S....EWADMQFLLWDAQRR.A....GI.........TDEQI....T.QA...MIEKLAVNKQRKWPEPKDGE.PRLHIKEQ.P--ap..........................
A0A976N0M3_9CAUD/99-167 .............................................lndfptndld--------------...--....-.-.--.--...-.--...-...-...--....-.-....-........-.-.....-.......-.-.....S....P......H....AWTYLTAIVVNLAGH.Y....GI.........SPQSL....Y.NA...VERKIEINKSRKWGKVDPNN.PDQPIHH-.---ied.........................
A0A6C2YPZ7_9BACT/54-155 ....................................................lld---ASWEWSQKTFG...SVe.yrG.P.KG.PL...L.HL...E...K...EV....R.E....Av.....qaI.G.....T.......P.E.....L....A......E....ELADCQLLIWDAARR.A....GL.........GPVEL....L.ME...VWKKLQKNQKRHWPKPTTDQ.PVEHLRED.---sk..........................
A0A6V8KBI2_9ACTN/106-202 ...................................................fvar----KREFSARTFG...PQ....A.L.AG.VI...D.HI...R...K...EL....V.E....V........E.A.....D.......P.T.....D....L......G....EWVDVIMLGLDGAWR.A....GH.........EPQEI....L.DA...IVAKQARCEARTWPDWRTTD.PGQAIEHD.---rgv.........................
A0AA49B4B0_9CAUD/11-88 .................................................lleaqr------AFSVRAFG..yHS....I.T.TG.VH...A.HL...L...E...EI....K.E....V........R.H.....D.......P.E.....D....L......T....EWADCLILALDGAHR.T....DA.........PLDYI....A.IR...INEI----------------.--------.---lkqpgat.....................
A0A514DFW6_9CAUD/75-172 ...................................................larq-----REFSLKTFG..pGA....R.T.NG.VI...D.HI...T...K...EL....V.E....V........R.E.....A.......P.D.....D....L......S....EWVDVIILAFDGAWR.S....GA.........EPQEI....I.DA...IIAKQAKNETREWPDWRSQD.PNKAIEHD.---rstd........................
A0AAE7SPB7_9CAUD/165-260 ..................................................lqqvi-----SEWADEVYP...DR....T.V.EN.AL..tK.MM...L...H...EI....P.E....L.......lH.G.....K.......A.M.....D....P......M....EFADVAILLFDVAHL.Q....GI.........---DI....A.QA...MRFKMKVNRNRKWEID----.--------.---patglmshvkppete.............
Q8HAI3_BPST6/139-235 .......................................................IRREHAEWSDKTFG...DV....G.P.VG.PL...K.HL...S...K...EA....L.E....A........A.A.....D.......P.S.....D....P......L....EWADMQFLLWDAQRR.A....GV.........TDEQI....T.MA...MVEKLAINKARQWPEPKDGE.PRLHIKEQ.P--ap..........................
A0A1V0DYC4_9CAUD/9-86 ...............................................lsrqcavg---------REKFG..pGE....R.T.KG.VM...D.HI...R...K...EF....D.E....I........E.A.....E.......E.T....pDg..rA......E....EWTDVAILGLDGLLR.A....--.........-----....-.--...--------------------.--------.---vremlrkqlskqevphgin.........
K9L979_BPK36/98-190 ......................................................v-RQAHAEWSDHQFG...NV....G.P.VG.PL...K.HL...A...K...EA....I.E....A........A.E.....A.......P.D.....D....I......S....EFADILMLVWDATRR.A....GF.........SDEQL....A.EA...VAEKLERNKRRVWGEVKDGE.PCHHVK--.---n...........................
A0A482IL99_9CAUD/63-159 ......................................................v-RREHAEWSQSTFG...NV....G.P.IG.PL...K.HL...R...R...EV....L.E....T........I.A.....K.......P.H.....D....L......I....EWADMQFLLWDAQRR.A....GI.........TDEQI....T.QA...MIDKLAVNKARQWPEPKDGE.PRMHLRSE.DE-s...........................
I6S1L7_9CAUD/139-235 .......................................................IRREHAEWSDKTFG...DV....G.P.VG.PL...K.HL...S...K...EA....L.E....A........A.A.....D.......P.S.....D....P......L....EWADMQFLLWDAQRR.A....GV.........TDEQI....T.MA...MVEKLAINKARQWPEPKDGE.PRLHIKEQ.P--ap..........................
A0A938YGA7_9ACTN/101-202 .....................................................hl--QRQSDFSQRTFG..pGL....R.T.AG.LI...D.HI...T...K...EL....A.E....L........A.A.....E.......P.E.....D....M......S....ERIDLVILALDGALR.LahyrGD.........PVTAV....I.DA...LVAKQERNEARTWPDWRTAP.EGKAIEHD.---rsv.........................
A0A916NC18_9BACT/69-167 ....................................................lek---ERFQWSQRTFR...AA....S.P.SG.CL...F.HL...R...R...EI....K.E....I........D.A.....Sln...agN.P.....D....P......V....EFADAQMMLWDTMQR.C....GI.........SLDEM....F.QA...FRDKFEKNKRRKWNQQPEGH.--------.---yehergihd...................
A0A5Q2F7D3_9CAUD/58-156 ..................................................hlerq-----RRFSERTFG..pGS....R.A.AG.VV...D.HI...R...K...EL....R.E....I........E.E.....A.......P.G.....D....L......A....EWVDVVILALDGAWR.T....GA.........TPAQI....I.DA...LLAKQAKNESRSWPDWRTAP.ADKAIEHDrAD-e...........................
A0A873WJ38_9CAUD/147-247 ...................................................cqrl----IADWANDIFP...DR....T.V.DE.AI...L.KM...N...K...EV....G.E....L........DdS.....K.......F.L.....D....A......G....EFADVAILLFDIAYL.A....GI.........---DI....E.RA...IENKMAINMKREWIKLEDGT.RQ-HI---.---saetvvaappmpp...............
A0A916YIZ0_9SPHN/155-227 ..............................................arvgfdwpd--------------...--....-.Q.RG.AA...D.KL...R...E...EI....G.E....F........E.A.....A.......T.N.....D....Ad...rlE....EAGDMLFAMVNWLRK.N....GI.........SAEDA....L.RA...ANAKFERR------------.--------.---fsgm........................
A0A1H0Q0B4_9ACTN/25-121 .....................................................hl--ERQAAWSRETFG..pAP....R.T.TG.IL...A.HI...G...S...EI....A.E....I........A.A.....A.......P.E.....D....L......S....EWMDVVILAFDGALR.V....AT.........P-AAV....V.AA...LVAKQDKNEGRTWPDWRQFG.DDEAIEHD.---rtg.........................
A0A3G3M710_9CAUD/42-138 .......................................................IRHEHAKWSDSTFG...CV....G.P.IG.PL...K.HL...S...K...EA....L.E....A........A.A.....E.......P.D.....D....L......S....EWADMQFLLWDAQRR.A....GI.........SDAEI....T.AA...MEDKLKINMERQWPEPKDGE.PRLHIKEP.GN-s...........................
VEAA_BPP22/83-179 .......................................................IRREHAEWSDKTFG...DV....G.P.VG.PL...K.HL...S...K...EA....L.E....A........A.A.....D.......P.S.....D....P......L....EWADMQFLLWDAQRR.M....GI.........SDEFI....T.RA...MIEKLEINKTRQWPEPKDGE.PRLHIKEQ.PES............................
DGTPH_BPSHA/166-259 ...................................................lqqm----ISEWADQVYP...DR....T.V.EN.AL..tK.MM...L...H...EI....P.E....L.......lH.G.....K.......A.M.....D....P......A....EFADVAILLFDVAHL.Q....GI.........---DI....A.QA...MREKMEINQARDWK------.--------.---idpatglmshvkpkg.............
A0A127EUZ2_9HYPH/7-114 ..................................................lirqm------AFSHATFG..pGE....R.T.DG.VI...N.HI...K...K...EL....I.E....V........H.D.....A.......H.G.....D....A......A....EWVDVVILALDGLTRrL....AFcngerndpqSVAEI....AcNM...IIGKQTRNEGRQWPDWRTAD.PTKAIEH-.---vrsk........................
DGTPH_BPPMB/149-243 ..................................................vqkli-----SGWADRTFP...DR....T.I.GE.AI...L.KL...K...K...EL....A.E....L........D.T.....A.......SyL.....D....A......G....EFADVAILLLDIAQL.A....GI.........---DI....A.TA...VANKMAINERRVWQRLEDGT.HQHVI---.---dggrtd......................
A0A977TG73_9CAUD/91-187 ......................................................v-RREHAEWSDKTFG...DV....G.P.VG.PL...K.HL...S...K...EA....L.E....T........A.A.....E.......P.D.....D....L......S....EWADMQFLLWDAQRR.A....GI.........SDEQI....T.LA...MVEKLAVNKKREWPEPKDGE.PRLHIKEQ.P--ap..........................
A0A976XLA7_9CAUD/145-241 .......................................................IRNDHAEWSQSTFG...NV....G.P.IG.PL...K.HL...S...K...EA....L.E....A........A.A.....E.......P.G.....D....L......S....EWADMQFLLWDAQRR.A....GI.........TDEQI....T.QA...MIEKLAVNKQRKWPEPKDGE.PRLHIKEQ.P--ap..........................
A0A1G7ND77_9GAMM/124-222 ..................................................hmhrq-----IAFSTRTFG..pGE....R.Q.QG.VI...D.HI...R...K...EL....R.E....I........E.D.....A.......P.N.....D....L......E....EWIDVVLLALDGAWR.S....GH.........TAAEV....V.AG...LDAKLSKNEQREWPDWRTSD.RTKAIEHD.---rtkd........................
A0A0H2V7N6_ECOL6/42-138 .......................................................IRHEHAKWSDSTFG...CV....G.P.IG.PL...K.HL...S...K...EA....L.E....A........A.A.....E.......P.D.....D....L......S....EWADMQFLLWDAQRR.A....GI.........SDAEI....T.VA...MEDKLKINMERQWPEPKDGE.PRLHIKEP.GN-s...........................
A0A1H0WNU9_9HYPH/8-107 .....................................................hl--RRQSTFSQATFG..pGE....R.T.LG.NL...D.HI...R...K...EL....I.E....I........E.K.....D.......P.H.....D....L......K....EWVDVMLLAFDGAMR.H....GY.........SPEAI....S.AT...IMAVQTRNENRIWPDWRTMS.HDHAIEHD.---rtadd.......................
A0A9Y1YYY6_9CAUD/99-191 ......................................................v-RQAHAEWSDRQFG...NV....G.P.VG.PL...K.HL...A...K...EA....N.E....A........A.E.....A.......P.D.....D....I......S....EFADILMLVWDATRR.A....GF.........SDEQL....A.EA...VAEKLERNKRRAWGEVKDGE.PCHHVK--.---n...........................
A0A976N0M3_9CAUD/6-88 .................................................lfnsqr------AFSAKAFS...GQ....T.P.LG.VF...K.HL...E...K...EA....V.E....L........E.A.....D.......P.N.....D....L......L....EWADCFILTIDGAMR.-....--.........-----....-.--...--------------------.--------.---srptvaspewcalrtteamreksklvtr
A0A7C9BV39_9BACT/55-151 ..................................................lekar-----MKWAAETFP...EA....T.A.LS.SI...Y.KL...R...E...EA....D.A....I........E.Q.....Nll...dgK.P.....D....P......M....EYADALMCLLDSAGR.A....GI.........TPLQI....L.EA...FQEKILINKSRKWVKNPD--.--------.---ntyshvkqd...................
A0A1G6UL80_9ACTN/97-195 ..................................................hlsrq-----RAWSETTFG..pGA....R.T.RG.VV...D.HI...R...K...EL....R.E....I........E.A.....A.......P.D.....D....L......G....EWVDVVILALDGAWR.S....GA.........SPKQI....I.AA...IRAKQARNESRTWPDWRTMS.PDQAIEH-.---vrtae.......................
A0AA36QK29_9CAUD/46-144 ..................................................hlerq-----RRFSERTFG..pGS....R.A.AG.VI...D.HI...R...K...EL....R.E....I........D.E.....A.......P.G.....D....L......A....EWIDVVILALDGAWR.T....GA.........TPAQI....I.DA...LVAKQTKNEARTWPDWRTAP.ADKAIEHVrA--de..........................
A0A2Z2FBB9_9CAUD/168-264 ......................................................v-RREHAEWSHATFG...NV....G.P.AG.PL...K.HL...S...I...EA....L.E....A........A.A.....E.......P.N.....D....H......S....EWADMQFLMWDAQRR.A....GI.........TDEQI....T.QA...MIDKLAVNKARQWPEPKDGE.PRMHLRSE.DE-s...........................
A0A7G8LPG0_9CAUD/6-82 ..................................................llkaq-----REFSVKAFG...DH....SfT.SG.VY...K.HL...L...K...EI....D.E....V........R.A.....A.......P.K.....D....I......E....EWADCLILALDGAHR.A....RY.........N----....-.--...--------------------.--------.---llyidarineflthkhk...........
A0A653FV81_9CAUD/42-138 .......................................................IRHEHAKWSDSTFG...CV....G.P.IG.PL...K.HL...S...K...EA....L.E....A........A.A.....E.......P.D.....D....L......S....EWADMQFLLWDAQRR.A....GI.........SDAEI....T.VA...MEDKLKINMERQWPEPKDGE.PRLHIKEP.GN-s...........................
A0A9X1JZS4_9RHOB/97-194 ......................................................v-IDHHIGFSFKTFG..pGE....R.L.AG.TL...D.HI...E...D...EL....V.E....I........K.A.....D.......P.H.....D....C......E....EWVDLILLAIQGAAR.H....GH.........NAEAI....A.GT...WLAKMSKNDARDWPDWRTAD.PTKRIEH-.---irtp........................
#=GC seq_cons ......................................................h.....tcWSppTFG...ss....t.s.hG.sl...c.Hl...p...K...Eh....h.E....h........t.u.....s.......P.s.....D....l......p....EWADhhhLhhDutpR.s....Gh.........osppI....s.pA...hhtKhthNctRpWP-.+suc.sphtIcc.....t...........................
//
