#=GF ID eIF2A
#=GF AC PF08662.15
#=GF DE Eukaryotic translation initiation factor eIF2A
#=GF AU Mistry J;0000-0003-2479-5322
#=GF AU Wood V;0000-0001-6330-7526
#=GF SE Pfam-B_7957 (release 19.0)
#=GF GA 20.50 20.50;
#=GF TC 20.50 20.50;
#=GF NC 20.40 20.40;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP Repeat
#=GF CL CL0186
#=GF RN [1]
#=GF RM 12133843
#=GF RT Characterization of mammalian eIF2A and identification of the
#=GF RT yeast homolog.
#=GF RA Zoll WL, Horton LE, Komar AA, Hensold JO, Merrick WC;
#=GF RL J Biol Chem. 2002;277:37079-37087.
#=GF DR INTERPRO; IPR013979;
#=GF DR SO; 0001068; polypeptide_repeat;
#=GF CC This is a family of eukaryotic translation initiation factors.
#=GF SQ 6494
#=GS A0A8B9CRD9_9AVES/210-405 AC A0A8B9CRD9.1
#=GS A0A7J9E0N3_9ROSI/110-310 AC A0A7J9E0N3.1
#=GS A0A165IZH7_EXIGL/397-573 AC A0A165IZH7.1
#=GS A0A6A5FNM7_PERFL/153-295 AC A0A6A5FNM7.1
#=GS A0A402B515_9CHLR/192-326 AC A0A402B515.1
#=GS A0A8C8AMM5_9STRI/413-608 AC A0A8C8AMM5.1
#=GS L5KA91_PTEAL/189-322 AC L5KA91.1
#=GS Q21IE6_SACD2/121-288 AC Q21IE6.1
#=GS A0A8C1CII0_CYPCA/375-570 AC A0A8C1CII0.1
#=GS A0A094HDX5_9PEZI/218-412 AC A0A094HDX5.1
#=GS C6HQK5_AJECH/220-414 AC C6HQK5.1
#=GS A0A8C7HMW8_ONCKI/167-285 AC A0A8C7HMW8.1
#=GS A0A7L2T4K3_POMRU/212-407 AC A0A7L2T4K3.1
#=GS A0A5N6R5E9_9ROSI/404-604 AC A0A5N6R5E9.1
#=GS A0A8C9KR28_PANTA/191-386 AC A0A8C9KR28.1
#=GS A0A427XFN7_9TREE/248-441 AC A0A427XFN7.1
#=GS W3XQP0_PESFW/406-630 AC W3XQP0.1
#=GS H2YIG8_CIOSA/155-348 AC H2YIG8.1
#=GS A0A158QBP2_HYMDI/255-391 AC A0A158QBP2.1
#=GS A0A5D2W1C6_GOSMU/406-606 AC A0A5D2W1C6.1
#=GS A0A673UTL4_SURSU/224-419 AC A0A673UTL4.1
#=GS A0A2S4KXQ2_9HYPO/404-628 AC A0A2S4KXQ2.1
#=GS A0A5N6JVY6_MONLA/234-393 AC A0A5N6JVY6.1
#=GS EIF3B_CULQU/377-579 AC B0W562.1
#=GS A0A672H8U5_SALFA/215-274 AC A0A672H8U5.1
#=GS A0A8D2NKK9_ZOSLA/236-376 AC A0A8D2NKK9.1
#=GS A0A7L1XVU7_9AVES/212-407 AC A0A7L1XVU7.1
#=GS A0A1L7WEP3_9HELO/407-631 AC A0A1L7WEP3.1
#=GS A0A7M7R612_APIME/389-591 AC A0A7M7R612.1
#=GS A0A8C2WQY4_CYCLU/155-294 AC A0A8C2WQY4.1
#=GS A0A814WQ71_9BILA/169-224 AC A0A814WQ71.1
#=GS A0A7K5HT96_CROSL/215-410 AC A0A7K5HT96.1
#=GS A0A371CUU9_9APHY/408-530 AC A0A371CUU9.1
#=GS A0A8D2B436_SCIVU/191-386 AC A0A8D2B436.1
#=GS A0A8J4ZIX2_9CHEL/476-647 AC A0A8J4ZIX2.1
#=GS A0A3P7L5G2_DIBLA/4-195 AC A0A3P7L5G2.1
#=GS A0A0Q3IHT9_BRADI/90-283 AC A0A0Q3IHT9.2
#=GS A0A672GTQ2_SALFA/158-272 AC A0A672GTQ2.1
#=GS A0A3N2PRF6_9PEZI/412-636 AC A0A3N2PRF6.1
#=GS A0A8R1HUK1_CAEJA/192-234 AC A0A8R1HUK1.1
#=GS A0A8J4FTY7_9CHLO/418-618 AC A0A8J4FTY7.1
#=GS A0A484DJU4_PERFV/215-410 AC A0A484DJU4.1
#=GS A0A3L6PTJ7_PANMI/142-307 AC A0A3L6PTJ7.1
#=GS A0A7K5FMY0_PROAR/211-406 AC A0A7K5FMY0.1
#=GS A0A8J8W1K0_9EURO/213-407 AC A0A8J8W1K0.1
#=GS C5XX81_SORBI/217-410 AC C5XX81.1
#=GS A0A3Q1AKN4_AMPOC/219-380 AC A0A3Q1AKN4.1
#=GS A0A672KEX0_SINGR/283-478 AC A0A672KEX0.1
#=GS A0A1V6UFE1_9EURO/213-407 AC A0A1V6UFE1.1
#=GS A0A498SBD2_ACAVI/804-1000 AC A0A498SBD2.1
#=GS A0A0U5G6J2_ASPCI/215-409 AC A0A0U5G6J2.1
#=GS A0A0V0VZ95_9BILA/381-591 AC A0A0V0VZ95.1
#=GS A0A8H4P2D3_9HYPO/217-411 AC A0A8H4P2D3.1
#=GS A0A3P8RI91_AMPPE/158-296 AC A0A3P8RI91.1
#=GS A0A671QMY2_9TELE/161-294 AC A0A671QMY2.1
#=GS A0A087XSS9_POEFO/215-409 AC A0A087XSS9.2
#=GS A0A7J7DBD8_TRIWF/405-605 AC A0A7J7DBD8.1
#=GS A0A1R1PHX5_ZANCU/125-318 AC A0A1R1PHX5.1
#=GS A0A1V4KLZ3_PATFA/1-117 AC A0A1V4KLZ3.1
#=GS A0A8H4USA2_9HYPO/404-628 AC A0A8H4USA2.1
#=GS A0A7K8KDZ8_9GRUI/212-407 AC A0A7K8KDZ8.1
#=GS A0A1U8JLR4_GOSHI/406-606 AC A0A1U8JLR4.1
#=GS B8PMT7_POSPM/213-407 AC B8PMT7.1
#=GS A0A3M7NTG6_9EURO/1331-1525 AC A0A3M7NTG6.1
#=GS A0A6P7YYN7_9AMPH/197-392 AC A0A6P7YYN7.1
#=GS A0A452QBU5_URSAM/392-587 AC A0A452QBU5.1
#=GS A0A1Z5KKU3_FISSO/384-611 AC A0A1Z5KKU3.1
#=GS A0A448YF95_BRENA/398-626 AC A0A448YF95.1
#=GS A0A7L3EYT2_9GRUI/215-410 AC A0A7L3EYT2.1
#=GS A0A8C4Z5D4_GADMO/363-558 AC A0A8C4Z5D4.1
#=GS A0A8H7V0Q0_9FUNG/213-406 AC A0A8H7V0Q0.1
#=GS A0A8J2N4P8_9PLEO/404-631 AC A0A8J2N4P8.1
#=GS A0A6I9MG30_PERMB/216-411 AC A0A6I9MG30.1
#=GS A0A5N6E5G2_ASPPA/402-625 AC A0A5N6E5G2.1
#=GS A0A7J7X9V0_PIPKU/504-699 AC A0A7J7X9V0.1
#=GS A0A8I3PP99_CANLF/191-386 AC A0A8I3PP99.1
#=GS A0A5N6RM52_9ROSI/404-604 AC A0A5N6RM52.1
#=GS A0A673A3D0_9TELE/177-293 AC A0A673A3D0.1
#=GS A0A8D0D6N3_SANLU/186-300 AC A0A8D0D6N3.1
#=GS A0A8C7MK71_ONCKI/368-566 AC A0A8C7MK71.1
#=GS A0A6P6LS40_CARAU/215-410 AC A0A6P6LS40.1
#=GS A0A2J6LSC7_LACSA/406-602 AC A0A2J6LSC7.1
#=GS A0A2G8RND4_9APHY/70-215 AC A0A2G8RND4.1
#=GS A0A1Y1VB39_9FUNG/111-226 AC A0A1Y1VB39.1
#=GS A0A5J4YU43_PORPP/243-434 AC A0A5J4YU43.1
#=GS L8FSU1_PSED2/407-632 AC L8FSU1.1
#=GS A0A7J6DIP7_9TELE/375-570 AC A0A7J6DIP7.1
#=GS A0A1U8MK46_GOSHI/406-606 AC A0A1U8MK46.1
#=GS A0A7K5D2U4_9TYRA/341-536 AC A0A7K5D2U4.1
#=GS A0A4D9D4W4_9STRA/254-451 AC A0A4D9D4W4.1
#=GS A0A8C0YDV1_CYPCA/149-291 AC A0A8C0YDV1.1
#=GS A0A250Y325_CASCN/216-411 AC A0A250Y325.1
#=GS A0A101MIS4_9EURO/403-626 AC A0A101MIS4.1
#=GS A0A5C6MVQ9_9TELE/166-280 AC A0A5C6MVQ9.1
#=GS A0A2R9AAG8_PANPA/322-465 AC A0A2R9AAG8.1
#=GS A0A4U5QM02_POPAL/405-606 AC A0A4U5QM02.1
#=GS EIF3B_DROPE/379-583 AC B4GAY7.1
#=GS A0A166WJ65_9PEZI/217-411 AC A0A166WJ65.1
#=GS A0A4Q4ZRB3_9PEZI/216-410 AC A0A4Q4ZRB3.1
#=GS A0A6A3AWN8_HIBSY/350-550 AC A0A6A3AWN8.1
#=GS A0A444EBE8_ENSVE/217-410 AC A0A444EBE8.1
#=GS A0A0N4T520_BRUPA/386-586 AC A0A0N4T520.1
#=GS A0A656KI08_BLUGR/216-410 AC A0A656KI08.1
#=GS A0A8C2T442_COTJA/176-294 AC A0A8C2T442.1
#=GS A0A8X7T3I7_9BASI/431-656 AC A0A8X7T3I7.1
#=GS A0A7L4K3W6_9AVES/341-536 AC A0A7L4K3W6.1
#=GS A0A8H6RPX7_9PEZI/401-625 AC A0A8H6RPX7.1
#=GS A0A673J4X7_9TELE/346-541 AC A0A673J4X7.1
#=GS A0A5N6J4I9_9EURO/402-625 AC A0A5N6J4I9.1
#=GS A0A7L2Q026_9PASS/341-536 AC A0A7L2Q026.1
#=GS A0A8I5R6A7_PAPAN/507-702 AC A0A8I5R6A7.1
#=GS A0A813PMR4_9BILA/174-316 AC A0A813PMR4.1
#=GS A0A2U9BMJ1_SCOMX/374-569 AC A0A2U9BMJ1.1
#=GS G1X7S8_ARTOA/395-620 AC G1X7S8.1
#=GS F4X5V9_ACREC/390-593 AC F4X5V9.1
#=GS A0A4U0EYU6_9FLAO/406-513 AC A0A4U0EYU6.1
#=GS A0A3B6PMD2_WHEAT/295-375 AC A0A3B6PMD2.1
#=GS A0A803VXE4_FICAL/395-598 AC A0A803VXE4.1
#=GS A0A835BDE5_9POAL/217-410 AC A0A835BDE5.1
#=GS A0A8D2ENL4_THEGE/155-350 AC A0A8D2ENL4.1
#=GS Q6CY67_KLULA/222-422 AC Q6CY67.1
#=GS A0A0C2ZNZ1_9AGAM/213-406 AC A0A0C2ZNZ1.1
#=GS A0A8H7GRG9_9ASCO/217-410 AC A0A8H7GRG9.1
#=GS A0A286UVC3_9AGAM/209-402 AC A0A286UVC3.1
#=GS B7FXH3_PHATC/384-595 AC B7FXH3.1
#=GS A0A8C7KA45_ONCKI/223-365 AC A0A8C7KA45.1
#=GS A0A1Y3NR17_PIRSE/383-583 AC A0A1Y3NR17.1
#=GS A0A7L1XW43_9AVES/445-640 AC A0A7L1XW43.1
#=GS A0A0N5CJD2_THECL/440-595 AC A0A0N5CJD2.1
#=GS A0A1J6K622_NICAT/588-788 AC A0A1J6K622.1
#=GS A0A7L0D3N6_9CHAR/448-643 AC A0A7L0D3N6.1
#=GS A0A5J4NN93_9TREM/125-258 AC A0A5J4NN93.1
#=GS A0D0J9_PARTE/1099-1235 AC A0D0J9.1
#=GS A0A8K0N530_COCNU/303-396 AC A0A8K0N530.1
#=GS A0A8H4S064_9HELO/216-410 AC A0A8H4S064.1
#=GS A0A3M7PXM9_BRAPC/277-392 AC A0A3M7PXM9.1
#=GS W9IX06_FUSOX/404-629 AC W9IX06.1
#=GS T0QIX6_SAPDV/227-421 AC T0QIX6.1
#=GS A0A7J7ZVJ6_MYOMY/232-372 AC A0A7J7ZVJ6.1
#=GS A0A0D1VQY1_9EURO/236-460 AC A0A0D1VQY1.1
#=GS A0A8H5QCB0_GIBSU/404-629 AC A0A8H5QCB0.1
#=GS S7ZH11_PENO1/403-626 AC S7ZH11.1
#=GS A0A7J8HNT6_ROUAE/181-376 AC A0A7J8HNT6.1
#=GS A0A063BZR8_USTVR/217-411 AC A0A063BZR8.1
#=GS A0A5N5XBL2_9EURO/402-625 AC A0A5N5XBL2.1
#=GS A0A6L8NX43_BACAN/14-186 AC A0A6L8NX43.1
#=GS A0A372QC16_9GLOM/399-632 AC A0A372QC16.1
#=GS A0A371DMG8_9APHY/408-631 AC A0A371DMG8.1
#=GS A0A0V0SH82_9BILA/381-591 AC A0A0V0SH82.1
#=GS A0A8I2YRX8_9AGAM/254-447 AC A0A8I2YRX8.1
#=GS F7W6R1_SORMK/217-411 AC F7W6R1.1
#=GS A0A674AAA4_SALTR/377-567 AC A0A674AAA4.1
#=GS B3RPX9_TRIAD/391-587 AC B3RPX9.1
#=GS A7S0D5_NEMVE/190-310 AC A7S0D5.1
#=GS A0A8X8WFB8_SALSN/406-606 AC A0A8X8WFB8.1
#=GS A0A8J2R506_9NEOP/384-617 AC A0A8J2R506.1
#=GS A0A8C4MZT0_EQUAS/216-411 AC A0A8C4MZT0.1
#=GS A0A3Q3AE61_KRYMA/215-410 AC A0A3Q3AE61.1
#=GS A0A8C9PXW7_SPEDA/216-411 AC A0A8C9PXW7.1
#=GS A0A1V8TCJ3_9PEZI/404-628 AC A0A1V8TCJ3.1
#=GS A2D7P9_TRIV3/149-304 AC A2D7P9.1
#=GS A0A8C4C821_9TELE/126-290 AC A0A8C4C821.1
#=GS A0A409X6T9_9AGAR/202-395 AC A0A409X6T9.1
#=GS A0A6A5FS49_PERFL/374-569 AC A0A6A5FS49.1
#=GS A0A251W819_9CYAN/74-204 AC A0A251W819.1
#=GS A0A8B9QG11_APTOW/383-578 AC A0A8B9QG11.1
#=GS A0A672MVY6_SINGR/300-385 AC A0A672MVY6.1
#=GS A0A7L1JHU3_RYNNI/177-294 AC A0A7L1JHU3.1
#=GS A0A2K3QPL3_9HYPO/217-411 AC A0A2K3QPL3.1
#=GS A0A2P5W8G8_GOSBA/320-442 AC A0A2P5W8G8.1
#=GS A0A8H7DVN8_PLEOS/569-630 AC A0A8H7DVN8.1
#=GS A0A4Z2CB37_9TELE/343-422 AC A0A4Z2CB37.1
#=GS A0A545AA29_9PEZI/216-410 AC A0A545AA29.1
#=GS A0A399GBS8_9PLEO/217-411 AC A0A399GBS8.1
#=GS G8C047_TETPH/199-358 AC G8C047.1
#=GS A0A1X1BLM9_9APIC/237-376 AC A0A1X1BLM9.1
#=GS A0A7K6LYU7_9CORV/341-536 AC A0A7K6LYU7.1
#=GS A0A8C0VRM4_CYACU/368-563 AC A0A8C0VRM4.1
#=GS A0A6P8ZIB8_THRPL/173-367 AC A0A6P8ZIB8.1
#=GS A0A4W5MJB6_9TELE/1-98 AC A0A4W5MJB6.1
#=GS A0A1S3CXM8_DIACI/1-57 AC A0A1S3CXM8.1
#=GS H3AQ44_LATCH/377-572 AC H3AQ44.1
#=GS A0A8C5IDJ1_JUNHY/216-411 AC A0A8C5IDJ1.1
#=GS A0A2K5QKX5_CEBIM/207-402 AC A0A2K5QKX5.1
#=GS A0A8I6Z1T8_HORVV/295-375 AC A0A8I6Z1T8.1
#=GS A0A4U0XTE5_9PEZI/1745-1939 AC A0A4U0XTE5.1
#=GS A0A8C7MXQ5_ONCKI/164-278 AC A0A8C7MXQ5.1
#=GS DCA13_PONAB/176-311 AC Q5R4T8.1
#=GS A0A7J6ZTJ1_9COLE/388-592 AC A0A7J6ZTJ1.1
#=GS A0A4V1XEY2_9PEZI/407-631 AC A0A4V1XEY2.1
#=GS A0A8C4V8T5_FALTI/223-418 AC A0A8C4V8T5.1
#=GS A0A384CYR6_URSMA/26-169 AC A0A384CYR6.1
#=GS A0A1S4BA51_TOBAC/404-523 AC A0A1S4BA51.1
#=GS A0A835K5U0_9ROSI/452-653 AC A0A835K5U0.1
#=GS G2YES7_BOTF4/216-410 AC G2YES7.1
#=GS A0A5A7TMY6_CUCME/216-409 AC A0A5A7TMY6.1
#=GS A0A7K5ASJ3_9FURN/432-627 AC A0A7K5ASJ3.1
#=GS A0A8H7AKD1_9EURO/219-413 AC A0A8H7AKD1.1
#=GS A0A165ETT5_9BASI/409-632 AC A0A165ETT5.1
#=GS A0A059LRS3_9CHLO/408-612 AC A0A059LRS3.1
#=GS A0A8C4A463_9TELE/375-570 AC A0A8C4A463.1
#=GS A0A1Y2V8A5_9PEZI/1149-1256 AC A0A1Y2V8A5.1
#=GS A0A0P7UZY8_SCLFO/178-306 AC A0A0P7UZY8.1
#=GS D8M4P8_BLAHO/277-486 AC D8M4P8.1
#=GS G0VBH5_NAUCC/191-353 AC G0VBH5.1
#=GS A0A2T9YWI1_9FUNG/401-635 AC A0A2T9YWI1.1
#=GS A0A397ZTU7_BRACM/402-602 AC A0A397ZTU7.1
#=GS W9WZ08_9EURO/217-411 AC W9WZ08.1
#=GS A0A8C7Z706_9TELE/368-546 AC A0A8C7Z706.1
#=GS A0A2A3EMN5_APICC/389-591 AC A0A2A3EMN5.1
#=GS EIF3B_ASPFU/401-624 AC Q4WKL7.1
#=GS A0A0D9VFI3_9ORYZ/121-282 AC A0A0D9VFI3.1
#=GS A0A7M7JSE1_VARDE/212-410 AC A0A7M7JSE1.1
#=GS A0A8C8FN81_ONCTS/277-472 AC A0A8C8FN81.1
#=GS B3SD89_TRIAD/43-175 AC B3SD89.1
#=GS A0A5N5DEH7_9PEZI/217-411 AC A0A5N5DEH7.1
#=GS A0A663NBE5_ATHCN/358-553 AC A0A663NBE5.1
#=GS A0A8H4XTQ0_9HYPO/35-195 AC A0A8H4XTQ0.1
#=GS A0A6J2XM37_SITOR/384-587 AC A0A6J2XM37.1
#=GS A0A087GYK1_ARAAL/360-446 AC A0A087GYK1.1
#=GS A0A7M7QED2_NASVI/21-169 AC A0A7M7QED2.1
#=GS A0A317XDG4_9EURO/403-626 AC A0A317XDG4.1
#=GS H9GEM3_ANOCA/583-778 AC H9GEM3.2
#=GS A0A7J9H6I9_9ROSI/365-565 AC A0A7J9H6I9.1
#=GS A0A2P8XJX2_BLAGE/387-493 AC A0A2P8XJX2.1
#=GS A0A673A3D0_9TELE/385-580 AC A0A673A3D0.1
#=GS A0A1Y2GLX6_9FUNG/394-560 AC A0A1Y2GLX6.1
#=GS A0A251VRX7_HELAN/106-266 AC A0A251VRX7.1
#=GS A0A4V6AB86_POPAL/405-606 AC A0A4V6AB86.1
#=GS J4G9K1_9APHY/413-573 AC J4G9K1.1
#=GS A0A833VNG3_9HYME/73-164 AC A0A833VNG3.1
#=GS A0A672GSX3_SALFA/408-603 AC A0A672GSX3.1
#=GS A0A665U5X3_ECHNA/226-326 AC A0A665U5X3.1
#=GS A0A0D2LHF2_9CHLO/1-116 AC A0A0D2LHF2.1
#=GS A0A671RVE3_9TELE/375-570 AC A0A671RVE3.1
#=GS A0A8J5VD18_9HYME/156-351 AC A0A8J5VD18.1
#=GS A0A453HFN4_AEGTS/96-297 AC A0A453HFN4.1
#=GS A0A7J8XLV5_GOSAI/365-565 AC A0A7J8XLV5.1
#=GS A0A452QB52_URSAM/400-595 AC A0A452QB52.1
#=GS M7CBC7_CHEMY/186-381 AC M7CBC7.1
#=GS A0A0V1H5X9_9BILA/222-416 AC A0A0V1H5X9.1
#=GS L8X405_THACA/1068-1246 AC L8X405.1
#=GS R0MP38_NOSB1/171-333 AC R0MP38.1
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