GenomeNet

Database: Pfam
Entry: fn3
LinkDB: fn3
Original site: fn3 
#=GF ID   fn3
#=GF AC   PF00041.24
#=GF DE   Fibronectin type III domain
#=GF AU   Sonnhammer ELL;0000-0002-9015-5588
#=GF SE   Swissprot_feature_table
#=GF GA   25.00 25.00;
#=GF TC   25.00 25.00;
#=GF NC   24.90 24.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Fibronectin_type_III_domain
#=GF CL   CL0159
#=GF RN   [1]
#=GF RM   2169613
#=GF RT   Structural design and molecular evolution of a cytokine receptor
#=GF RT   superfamily. 
#=GF RA   Bazan JF; 
#=GF RL   PNAS USA 1990;87:6934-6938.
#=GF RN   [2]
#=GF RM   7528812
#=GF RT   Tracing the spread of fibronectin type III domains in bacterial
#=GF RT   glycohydrolases. 
#=GF RA   Little E, Bork P, Doolittle R; 
#=GF RL   J Mol Evol 1994;39:631-643.
#=GF RC   Definition of fibronectin domains
#=GF RN   [3]
#=GF RM   2992939
#=GF RT   Primary structure of human fibronectin: differential splicing
#=GF RT   may generate at least 10 polypeptides from a single gene. 
#=GF RA   Kornblihtt AR, Umezawa K, Vibe-Pedersen K, Baralle FE; 
#=GF RL   EMBO J 1985;4:1755-1759.
#=GF DR   INTERPRO; IPR003961;
#=GF DR   PROSITE; PDOC00214;
#=GF DR   PRINTS; PR00014;
#=GF DR   SCOP; 1ttf; sf;
#=GF DR   SMART; FN3;
#=GF DR   HOMSTRAD; fn3;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF SQ   422883
#=GS A0A6P3HJ08_BISBI/370-459      AC A0A6P3HJ08.1
#=GS A0A2I4CJB5_9TELE/525-603      AC A0A2I4CJB5.1
#=GS A0A4W5PR46_9TELE/710-800      AC A0A4W5PR46.1
#=GS A0A2Y9GYC1_NEOSC/814-900      AC A0A2Y9GYC1.1
#=GS A0A2I2UVH4_FELCA/3916-4006    AC A0A2I2UVH4.2
#=GS A0A3P8SWB6_AMPPE/261-356      AC A0A3P8SWB6.1
#=GS A0A6P6JQC0_CARAU/416-501      AC A0A6P6JQC0.1
#=GS A0A096MTQ4_PAPAN/26147-26230  AC A0A096MTQ4.2
#=GS A0A4W3IEJ3_CALMI/398-494      AC A0A4W3IEJ3.1
#=GS A0A2Y9M124_DELLE/598-684      AC A0A2Y9M124.1
#=GS A0A665UP74_ECHNA/915-993      AC A0A665UP74.1
#=GS A0A6A4VX20_AMPAM/2762-2848    AC A0A6A4VX20.1
#=GS A0A6J0UIT3_9SAUR/348-436      AC A0A6J0UIT3.1
#=GS A0A2Y9HM55_NEOSC/598-686      AC A0A2Y9HM55.1
#=GS A0A663F9Y8_AQUCH/2139-2226    AC A0A663F9Y8.1
#=GS A0A2R9B6P5_PANPA/17909-17992  AC A0A2R9B6P5.1
#=GS A0A1U8CSS1_MESAU/415-500      AC A0A1U8CSS1.1
#=GS A0A6P7KMH4_9TELE/20399-20484  AC A0A6P7KMH4.1
#=GS A0A6I9I9U2_VICPA/330-425      AC A0A6I9I9U2.1
#=GS A0A6J3EAU3_AYTFU/824-909      AC A0A6J3EAU3.1
#=GS A0A087X7Y5_POEFO/15253-15338  AC A0A087X7Y5.2
#=GS A0A4S2L5U5_9HYME/624-709      AC A0A4S2L5U5.1
#=GS A0A7N6FCT9_ANATE/921-1021     AC A0A7N6FCT9.1
#=GS A0A6P8H421_CLUHA/11960-12045  AC A0A6P8H421.1
#=GS A0A6J2WL63_CHACN/522-611      AC A0A6J2WL63.1
#=GS A0A6I8WD83_DROPS/22192-22277  AC A0A6I8WD83.1
#=GS A0A6P7MMS3_BETSP/611-699      AC A0A6P7MMS3.1
#=GS A0A5J5D702_9PERO/492-573      AC A0A5J5D702.1
#=GS A0A2K5NPW2_CERAT/12193-12284  AC A0A2K5NPW2.1
#=GS A0A341AYE3_NEOAA/2732-2811    AC A0A341AYE3.1
#=GS A0A4Z2HX29_9TELE/2930-3014    AC A0A4Z2HX29.1
#=GS A0A803K4K4_XENTR/221-302      AC A0A803K4K4.1
#=GS D6WDG5_TRICA/388-469          AC D6WDG5.1
#=GS A0A6P8TC61_GYMAC/16707-16790  AC A0A6P8TC61.1
#=GS A0A6P6KTW9_CARAU/12188-12275  AC A0A6P6KTW9.1
#=GS A0A6A5EU09_PERFL/3271-3345    AC A0A6A5EU09.1
#=GS A0A6P6ER90_OCTDE/23649-23734  AC A0A6P6ER90.1
#=GS G1M3Q0_AILME/1057-1137        AC G1M3Q0.2
#=GS A0A3Q1AJS0_AMPOC/608-693      AC A0A3Q1AJS0.1
#=GS A0A3Q2HUA6_HORSE/894-977      AC A0A3Q2HUA6.1
#=GS A0A6I9IDC7_VICPA/1450-1530    AC A0A6I9IDC7.1
#=GS A0A2K5JR95_COLAP/20090-20175  AC A0A2K5JR95.1
#=GS A0A3Q0FN06_ALLSI/747-818      AC A0A3Q0FN06.1
#=GS A0A3B5Q4Q8_XIPMA/1196-1283    AC A0A3B5Q4Q8.1
#=GS A0A3Q2UZW1_HAPBU/566-651      AC A0A3Q2UZW1.1
#=GS A0A6J2PAQ0_COTGO/14705-14788  AC A0A6J2PAQ0.1
#=GS A0A1S3P2I2_SALSA/748-832      AC A0A1S3P2I2.1
#=GS A0A6I8QW11_XENTR/2515-2591    AC A0A6I8QW11.2
#=GS A0A6J3GAZ9_SAPAP/306-388      AC A0A6J3GAZ9.1
#=GS A0A340Y4X3_LIPVE/549-633      AC A0A340Y4X3.1
#=GS A0A4W6G9U6_LATCA/681-779      AC A0A4W6G9U6.1
#=GS A0A6P7LUP6_BETSP/632-713      AC A0A6P7LUP6.1
#=GS A0A672JPV5_SALFA/347-428      AC A0A672JPV5.1
#=GS B7ZNJ1_MOUSE/1092-1162        AC B7ZNJ1.1
#=GS A0A674NGA1_TAKRU/334-419      AC A0A674NGA1.1
#=GS A0A2K5Z3G5_MANLE/8007-8091    AC A0A2K5Z3G5.1
#=GS A0A3Q2HD92_HORSE/1348-1420    AC A0A3Q2HD92.1
#=GS A0A673HXA2_9TELE/110-199      AC A0A673HXA2.1
#=GS A0A2Y9TH07_PHYMC/2198-2276    AC A0A2Y9TH07.1
#=GS A0A6P6KTY7_CARAU/22046-22132  AC A0A6P6KTY7.1
#=GS A0A1D5PDF4_CHICK/948-1028     AC A0A1D5PDF4.2
#=GS F1R7N8_DANRE/14858-14944      AC F1R7N8.3
#=GS A0A6J0XPY9_ODOVR/38-120       AC A0A6J0XPY9.1
#=GS A0A6P5IVN3_PHACI/885-963      AC A0A6P5IVN3.1
#=GS A0A671U3C0_SPAAU/829-919      AC A0A671U3C0.1
#=GS A0A0N4V7F1_ENTVE/76-170       AC A0A0N4V7F1.1
#=GS A0A668V419_OREAU/1827-1909    AC A0A668V419.1
#=GS A0A5N4E759_CAMDR/17293-17379  AC A0A5N4E759.1
#=GS A0A0Q9X6K5_DROMO/888-972      AC A0A0Q9X6K5.1
#=GS A0A2K5LBU3_CERAT/1262-1349    AC A0A2K5LBU3.1
#=GS A0A287D0Y7_ICTTR/884-962      AC A0A287D0Y7.1
#=GS A0A6P6KQY7_CARAU/14714-14810  AC A0A6P6KQY7.1
#=GS A0A7F5RC14_AGRPL/1525-1612    AC A0A7F5RC14.1
#=GS A0A1A6H111_NEOLE/688-766      AC A0A1A6H111.1
#=GS A0A671YC72_SPAAU/718-799      AC A0A671YC72.1
#=GS A0A4W6F022_LATCA/882-965      AC A0A4W6F022.1
#=GS A0A6J2PAP4_COTGO/12440-12525  AC A0A6J2PAP4.1
#=GS E9Q8K5_MOUSE/23467-23552      AC E9Q8K5.1
#=GS H2QTA4_PANTR/2205-2283        AC H2QTA4.1
#=GS A0A6I9HEX5_GEOFO/1649-1740    AC A0A6I9HEX5.1
#=GS A0A673BC44_9TELE/392-477      AC A0A673BC44.1
#=GS A0A4W6E2F3_LATCA/871-955      AC A0A4W6E2F3.1
#=GS A0A7N8WL81_9TELE/914-1002     AC A0A7N8WL81.1
#=GS A0A6J1TZD8_9SAUR/24762-24846  AC A0A6J1TZD8.1
#=GS A0A6P6ERE1_OCTDE/17341-17430  AC A0A6P6ERE1.1
#=GS A0A2R9A484_PANPA/625-710      AC A0A2R9A484.1
#=GS A0A6J2A7U7_ACIJB/290-374      AC A0A6J2A7U7.1
#=GS A0A6J2PA66_COTGO/14192-14278  AC A0A6J2PA66.1
#=GS A0A6P8QZN4_GEOSA/28103-28188  AC A0A6P8QZN4.1
#=GS A0A2U3WK61_ODORO/363-447      AC A0A2U3WK61.1
#=GS A0A671F772_RHIFE/1008-1097    AC A0A671F772.1
#=GS A0A672NPX2_SINGR/929-1015     AC A0A672NPX2.1
#=GS A0A6J3D624_AYTFU/21771-21856  AC A0A6J3D624.1
#=GS A0A6P8H308_CLUHA/17961-18046  AC A0A6P8H308.1
#=GS A0A7M7QF46_NASVI/1408-1492    AC A0A7M7QF46.1
#=GS A0A5F4DNE9_CANLF/1619-1699    AC A0A5F4DNE9.1
#=GS A0A3Q3L5T9_9TELE/76-152       AC A0A3Q3L5T9.2
#=GS A0A4X2LD50_VOMUR/811-890      AC A0A4X2LD50.1
#=GS H0VMA2_CAVPO/1360-1439        AC H0VMA2.1
#=GS A0A6P8TC61_GYMAC/14144-14230  AC A0A6P8TC61.1
#=GS A0A6J2YG05_SITOR/3324-3409    AC A0A6J2YG05.1
#=GS A0A2I2YBJ5_GORGO/23662-23747  AC A0A2I2YBJ5.1
#=GS A0A3Q0FSN3_ALLSI/4680-4759    AC A0A3Q0FSN3.1
#=GS A0A384C1F9_URSMA/812-891      AC A0A384C1F9.1
#=GS A0A6P6Q0V0_CARAU/19404-19487  AC A0A6P6Q0V0.1
#=GS A0A6I8PCS9_ORNAN/806-891      AC A0A6I8PCS9.1
#=GS A0A7N8WUD1_9TELE/217-304      AC A0A7N8WUD1.1
#=GS B7QFI5_IXOSC/47-128           AC B7QFI5.1
#=GS W5MLI8_LEPOC/222-305          AC W5MLI8.1
#=GS A0A673TAH8_SURSU/724-802      AC A0A673TAH8.1
#=GS A0A2U9B440_SCOMX/630-718      AC A0A2U9B440.1
#=GS A0A6P8SDQ3_GEOSA/2330-2407    AC A0A6P8SDQ3.1
#=GS A0A182EEA5_ONCOC/446-532      AC A0A182EEA5.1
#=GS A0A1S2ZR08_ERIEU/827-913      AC A0A1S2ZR08.1
#=GS A0A1S3M993_SALSA/1569-1647    AC A0A1S3M993.1
#=GS A0A6J1QDI2_9HYME/3054-3139    AC A0A6J1QDI2.1
#=GS A0A673FJ71_9TELE/1449-1528    AC A0A673FJ71.1
#=GS A0A7M7PWL9_NASVI/6200-6287    AC A0A7M7PWL9.1
#=GS A0A6P7M4F3_BETSP/4686-4762    AC A0A6P7M4F3.1
#=GS A0A1A6GS68_NEOLE/799-857      AC A0A1A6GS68.1
#=GS A0A663FJN4_AQUCH/942-1021     AC A0A663FJN4.1
#=GS A0A2I3HI23_NOMLE/1900-1980    AC A0A2I3HI23.1
#=GS F7FBM0_MACMU/18672-18755      AC F7FBM0.3
#=GS A0A671RGH1_9TELE/242-314      AC A0A671RGH1.1
#=GS A0A2K5ZSF1_MANLE/789-875      AC A0A2K5ZSF1.1
#=GS A0A672MN80_SINGR/926-1010     AC A0A672MN80.1
#=GS A0A6P7LW62_BETSP/432-517      AC A0A6P7LW62.1
#=GS A0A6J0TWY2_9SAUR/631-719      AC A0A6J0TWY2.1
#=GS M7BH22_CHEMY/455-529          AC M7BH22.1
#=GS A0A2R9CEP8_PANPA/339-423      AC A0A2R9CEP8.1
#=GS A0A7N5ZRB3_ANATE/591-671      AC A0A7N5ZRB3.1
#=GS A0A6P6JFG0_CARAU/841-934      AC A0A6P6JFG0.1
#=GS A0A158QWX3_NIPBR/57-149       AC A0A158QWX3.1
#=GS A0A6P6Q0X0_CARAU/15666-15751  AC A0A6P6Q0X0.1
#=GS A0A2Y9QGK8_DELLE/523-605      AC A0A2Y9QGK8.1
#=GS F7AS17_HORSE/384-469          AC F7AS17.3
#=GS A0A6P8R4G0_GEOSA/32212-32295  AC A0A6P8R4G0.1
#=GS A0A3Q0G199_ALLSI/1158-1238    AC A0A3Q0G199.1
#=GS G1K2X0_DANRE/14432-14523      AC G1K2X0.2
#=GS A0A7E6DS82_9CHIR/608-696      AC A0A7E6DS82.1
#=GS G1KRT6_ANOCA/1998-2078        AC G1KRT6.2
#=GS A0A384ABK8_BALAS/337-434      AC A0A384ABK8.1
#=GS A0A6P6DAA8_OCTDE/742-827      AC A0A6P6DAA8.1
#=GS A0A2I3T6Q0_PANTR/17515-17600  AC A0A2I3T6Q0.1
#=GS A0A060X4L1_ONCMY/6-56         AC A0A060X4L1.1
#=GS A0A6J3QL96_TURTR/201-288      AC A0A6J3QL96.1
#=GS A0A6I8SYC9_XENTR/433-517      AC A0A6I8SYC9.1
#=GS A0A6I9Q2N7_9TELE/765-852      AC A0A6I9Q2N7.1
#=GS A0A7M7L453_APIME/3655-3740    AC A0A7M7L453.1
#=GS A0A668V1Y8_OREAU/1590-1671    AC A0A668V1Y8.1
#=GS A0A182H7L1_AEDAL/1652-1737    AC A0A182H7L1.1
#=GS A0A2I3TL46_PANTR/810-893      AC A0A2I3TL46.1
#=GS A0A6J0CN16_PERMB/23621-23705  AC A0A6J0CN16.1
#=GS A0A6J0CM66_PERMB/16471-16561  AC A0A6J0CM66.1
#=GS A0A6J2YG05_SITOR/6282-6366    AC A0A6J2YG05.1
#=GS H0YXF1_TAEGU/2517-2593        AC H0YXF1.2
#=GS A0A4W6E6B5_LATCA/333-413      AC A0A4W6E6B5.1
#=GS A0A096M104_POEFO/208-293      AC A0A096M104.1
#=GS H3C438_TETNG/988-1070         AC H3C438.1
#=GS A0A452EJM8_CAPHI/544-627      AC A0A452EJM8.1
#=GS A0A3Q7U9T4_URSAR/809-902      AC A0A3Q7U9T4.1
#=GS J3KQU5_HUMAN/79-179           AC J3KQU5.2
#=GS A0A6I8N1E8_ORNAN/770-857      AC A0A6I8N1E8.1
#=GS A0A6P6Q4P8_CARAU/1088-1164    AC A0A6P6Q4P8.1
#=GS B9EHT6_MOUSE/721-800          AC B9EHT6.1
#=GS A0A6J0CNP2_PERMB/28741-28825  AC A0A6J0CNP2.1
#=GS A0A6J2PAN8_COTGO/11411-11498  AC A0A6J2PAN8.1
#=GS A0A665X4Z0_ECHNA/726-811      AC A0A665X4Z0.1
#=GS A0A6J0CNV1_PERMB/26003-26087  AC A0A6J0CNV1.1
#=GS H2SP23_TAKRU/1225-1305        AC H2SP23.3
#=GS A0A6J1TZF2_9SAUR/20754-20839  AC A0A6J1TZF2.1
#=GS A0A212ET51_DANPL/340-422      AC A0A212ET51.1
#=GS E9Q8K5_MOUSE/14624-14709      AC E9Q8K5.1
#=GS A0A2U3W3P3_ODORO/458-537      AC A0A2U3W3P3.1
#=GS A0A6J2PB73_COTGO/12257-12342  AC A0A6J2PB73.1
#=GS G5B0U1_HETGA/29554-29637      AC G5B0U1.1
#=GS A0A3B0KQR8_DROGU/2794-2879    AC A0A3B0KQR8.1
#=GS A0A6J8DR47_MYTCO/400-483      AC A0A6J8DR47.1
#=GS A0A384D996_URSMA/384-468      AC A0A384D996.1
#=GS A0A3Q1CDL2_AMPOC/1139-1226    AC A0A3Q1CDL2.1
#=GS A0A2K5VSH8_MACFA/600-686      AC A0A2K5VSH8.2
#=GS A0A6F9CFD6_9TELE/2761-2846    AC A0A6F9CFD6.1
#=GS A0A044V1J0_ONCVO/1275-1364    AC A0A044V1J0.1
#=GS A0A671G6Q2_RHIFE/8075-8158    AC A0A671G6Q2.1
#=GS A0A2Y9ND87_DELLE/813-895      AC A0A2Y9ND87.1
#=GS A0A3Q1D2D7_AMPOC/47-127       AC A0A3Q1D2D7.1
#=GS A0A5C6PQX1_9TELE/169-258      AC A0A5C6PQX1.1
#=GS A0A670I9S8_PODMU/1468-1551    AC A0A670I9S8.1
#=GS A0A672RNJ7_SINGR/594-679      AC A0A672RNJ7.1
#=GS I3KWM9_ORENI/568-656          AC I3KWM9.2
#=GS A0A6P8VPN7_GYMAC/1137-1227    AC A0A6P8VPN7.1
#=GS A0A6J3BVT1_GALME/7004-7089    AC A0A6J3BVT1.1
#=GS A0A6I8VDM7_DROPS/1120-1207    AC A0A6I8VDM7.1
#=GS A0A2Y9PW15_DELLE/723-807      AC A0A2Y9PW15.1
#=GS A0A7M7L0Z2_APIME/3616-3699    AC A0A7M7L0Z2.1
#=GS A0A7R5K3I2_9PASS/332-426      AC A0A7R5K3I2.1
#=GS A0A7F8QQ86_LEPWE/3711-3801    AC A0A7F8QQ86.1
#=GS A0A2K6BHT4_MACNE/1889-1961    AC A0A2K6BHT4.1
#=GS F6TD21_CIOIN/6938-7020        AC F6TD21.2
#=GS A0A671KJU4_9TELE/412-478      AC A0A671KJU4.1
#=GS A0A6J0CME0_PERMB/23345-23430  AC A0A6J0CME0.1
#=GS H2R7G3_PANTR/3061-3141        AC H2R7G3.2
#=GS A0A670YH56_PSETE/1609-1690    AC A0A670YH56.1
#=GS A0A091PLY8_LEPDC/604-688      AC A0A091PLY8.1
#=GS A0A673HK81_9TELE/469-550      AC A0A673HK81.1
#=GS A0A6P7KJA4_9TELE/16843-16928  AC A0A6P7KJA4.1
#=GS A0A437D3Z6_ORYJA/1022-1111    AC A0A437D3Z6.1
#=GS B4J1N7_DROGR/1175-1264        AC B4J1N7.1
#=GS A0A672Z6E8_9TELE/1488-1565    AC A0A672Z6E8.1
#=GS A0A0P9BTF5_DROAN/5785-5872    AC A0A0P9BTF5.1
#=GS A0A1V4K6Q0_PATFA/28805-28889  AC A0A1V4K6Q0.1
#=GS A0A4W6BSB8_LATCA/803-889      AC A0A4W6BSB8.1
#=GS A0A6P8H2G5_CLUHA/27261-27345  AC A0A6P8H2G5.1
#=GS A0A6P8YU12_THRPL/1468-1548    AC A0A6P8YU12.1
#=GS A0A674BVN1_SALTR/334-414      AC A0A674BVN1.1
#=GS A0A6P8ERK4_CLUHA/903-985      AC A0A6P8ERK4.1
#=GS A0A3Q2CE86_CYPVA/597-682      AC A0A3Q2CE86.1
#=GS A0A2R9B6M8_PANPA/18894-18978  AC A0A2R9B6M8.1
#=GS A0A6I9NAQ7_9TELE/1008-1092    AC A0A6I9NAQ7.1
#=GS SDK_CAEEL/1157-1244           AC Q9N3X8.2
#=GS A0A2I0MXP6_COLLI/219-302      AC A0A2I0MXP6.1
#=GS A0A341CVM4_NEOAA/713-794      AC A0A341CVM4.1
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