#=GF ID   fvmJAB_N
#=GF AC   PF20011.4
#=GF DE   JAB N-terminal domain
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF SE   Aravind L
#=GF GA   27.00 27.00;
#=GF TC   27.40 30.30;
#=GF NC   26.00 22.00;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 4 -Z 81514348 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0366
#=GF RN   [1]
#=GF RM   32101166
#=GF RT   Highly regulated, diversifying NTP-dependent biological conflict
#=GF RT   systems with implications for the emergence of multicellularity.
#=GF RA   Kaur G, Burroughs AM, Iyer LM, Aravind L;
#=GF RL   Elife. 2020; [Epub ahead of print]
#=GF DR   INTERPRO; IPR045476;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Domain observed N-terminal to JAB deubiquitinase in the Ub
#=GF CC   system component of the FtsH ternary systems, a class of
#=GF CC   NTP-dependent biological conflict systems.
#=GF SQ   28
#=GS A0A7K2FTD0_9ACTN/5-162   AC A0A7K2FTD0.1
#=GS A0A451CH50_9GAMM/50-167  AC A0A451CH50.1
#=GS A0A7W7MSX9_9ACTN/5-162   AC A0A7W7MSX9.1
#=GS A0A1S2Q040_9ACTN/12-170  AC A0A1S2Q040.1
#=GS A0A840P603_9ACTN/18-161  AC A0A840P603.1
#=GS A0A1V1NVW6_9BACT/7-165   AC A0A1V1NVW6.1
#=GS A0A919PWX6_9ACTN/5-162   AC A0A919PWX6.1
#=GS A0A0F5VWX9_9ACTN/12-170  AC A0A0F5VWX9.1
#=GS A0A4R2J5Z7_9PSEU/5-175   AC A0A4R2J5Z7.1
#=GS A0A919D5D9_9ACTN/12-170  AC A0A919D5D9.1
#=GS K9UZM0_9CYAN/9-185       AC K9UZM0.1
#=GS A0A931C715_9ACTN/15-172  AC A0A931C715.1
#=GS A0A918IEF0_9ACTN/12-170  AC A0A918IEF0.1
#=GS A0A545AZJ8_9ACTN/5-164   AC A0A545AZJ8.1
#=GS A0A944L2R0_9ACTN/9-166   AC A0A944L2R0.1
#=GS A0A101P0U1_9ACTN/12-170  AC A0A101P0U1.1
#=GS A0A5N8XGB6_9ACTN/6-163   AC A0A5N8XGB6.1
#=GS A0A1G7X3Y9_9ACTN/5-174   AC A0A1G7X3Y9.1
#=GS A0A5M3XQP3_9ACTN/5-167   AC A0A5M3XQP3.1
#=GS A0A926L2S6_9ACTN/5-162   AC A0A926L2S6.1
#=GS A0A7W7V988_9ACTN/12-170  AC A0A7W7V988.1
#=GS A0A1V1NV25_9BACT/4-142   AC A0A1V1NV25.1
#=GS A0A8T4F1U9_9ACTN/6-175   AC A0A8T4F1U9.1
#=GS A0A8J3VLP2_9ACTN/12-169  AC A0A8J3VLP2.1
#=GS A0A2U3A626_9ACTN/5-174   AC A0A2U3A626.1
#=GS A0A1H2AII6_9ACTN/5-158   AC A0A1H2AII6.1
#=GS A0A252E5P0_9NOSO/9-178   AC A0A252E5P0.1
#=GS A0A917VLG8_9ACTN/1-162   AC A0A917VLG8.1
A0A7K2FTD0_9ACTN/5-162              .......................VELYRGDAHVPERRVGLIALLKAVL............ADELAADRRRAA..FNLRFQ...PIE..........DPE.....DYPGPPLLKNRQSGYGYLNVMAQVEG...RVIYRHPHSVKGLLGPALTALAREI.....DASEEY.......WSFRIDA.PGMDDAPVR.RLPPPV................SGAMDVDISRSA...RLSFGVRPAAEPELPE--fd..............................
A0A451CH50_9GAMM/50-167             ypwednrvrlaqpsehfldyhtd-------------------------............------------..------...---..........---.....-------------AIGFIQIEIVYAN...RFLYRHPHTVAEVLGPGLIAWLQEA.....GIEK-A.......AAYRITG.EGIGRL-VH.RSAPIP................EGVTEVTPYAPG..eGPAFRIRPIPP-------appepkt.........................
A0A7W7MSX9_9ACTN/5-162              .......................IDLYRSDDYVRAGRIDLLALLMPLF............ERVLGESLRDTL..FTLKFH...PIS..........DLR.....ELYGEPSLLNLRSSHGYVTVQITRGG...RVIYQHPHAVREIIGRPLQRILSEQ.....VPDERQ.......WGFGVSG.PGLEAITLE.RPAPRQ................VGAVDVAVRQAG...PRVLHMEEMPDPEPP---lad.............................
A0A1S2Q040_9ACTN/12-170             .......................VLLYKGTSFELVGKMTLSSLLVEAV............RRELAGGDPEEQ..LVLEIRy.lRRP..........DPR.....LADGPRTIHNLRSQIGRLALTVTRGS...EKVVDGEYPVRELLGPVLQHVVQQI.....DPDEEV.......WGFCLDH.PSLSGVALG.RSTPEV................EGTMDLNLRESR...-RSFTVRKVAEPPMP---gld.............................
A0A840P603_9ACTN/18-161             ................edtsdgr----------VFDVAPMMPLVRRAL............ARHLAEDHE-VD..IELRFGgagGRQ..........AAG.....TAHEPAHIPYLDTEPSRVEVQVTHKD...ATLHSGAYLVRELFGKVMTELAARM.....RDPDAR.......WGYRLVN.---------.------................------------...------------------vgrdrplvfrapalrvkdetllqvairpiqag
A0A1V1NVW6_9BACT/7-165              ........iellddnhqtidqpr---------------DFMAVAEPFL............NQLLGDLWKTADppVAILMA..iPGD..........DNN.....LY-GDDPLTYHTPAIGYIQLRIHYQG...RMQYYHPHSIVEVLTPGLRQWLSEL.....SRPPKA.......EGYRIKT.PNIRQLV-R.KSTPIP................KGVTEITPYAPG..eQPSFRIRPIP--------ppspeln.........................
A0A919PWX6_9ACTN/5-162              .......................VDVYRSDDYVKVGRVSLHSLLRGVF............EDVLGQSLDDAR..FTLDLH...AVE..........DLR.....ELTGPPAMINLRRSHGFLNVRISRKG...VLLYQHPHSIQELVGRPLQRMLTLL.....QPEETH.......WGYGIAG.PGMERVSLV.RPAPRP................AGVVEVRTTSGR...PRVFHLEAVQEPDPPTA-t...............................
A0A0F5VWX9_9ACTN/12-170             .......................VLLYKSTSFDLLGHMSLTSLLVEAF............RRELEPGDPEDE..VDIRLRy.vRRP..........DPR.....LIDGPRTIHNLRSQIGRLGVTISRRG...DTVVDREFSVRELLGPVLQHVVQQI.....DPEEEV.......WGFCLDH.PSLAMVALA.RSTPEV................EGTMDLNLRESR...-RNFAIRKVEEPPVPRI-a...............................
A0A4R2J5Z7_9PSEU/5-175              ......................l-EVFRARDKEPYCRYDFASVLRRAA............LRTFGDMARRGK..IELTLE...EAE..........AGG.....THPGPPEVRNLVARDGNCVLRLIQDG...KTAQEVRLPTVDLVGPVLADELRQV.....RPGERH.......WSFRLRQ.RRVTALIVLgDKIAEQltrlsg....rpepviEGSMDVDPRKDR...HQPFEVTQIEDQDE----qlvq............................
A0A919D5D9_9ACTN/12-170             .......................VLLYKGTSFDLVGKLTLSSLMVEAL............RRELPGGEPEEP..LIMHLRy.vRRP..........DPR.....LVDGPRTIHNLRSQIGRLGVIVSQAG...ETIIDREYPVRELLGPVLQHVVQQL.....DPDEQV.......WGFCIDH.PSLSGLALG.RSTPEV................EGTMDLNLRESR...-RSFTVRKVAEPPVPS--vd..............................
K9UZM0_9CYAN/9-185                  .......................IELYRGENRKFFGSIPFLPIVRESL............ERLLGHSLLLES..IQIIIL...QVP..........EEP.....LWMESPIIENLVPEFGYTYIRVYQGN...FLIYQHPHRFYDVVTQTLQTTLSNQ.....YPEETW.......WGFRVDI.PGIPQIAAA.NLQPQAstlysnlysktqlserLQSESLQIRQQPqevKPSFKIRRLEEEEPAIKT................................
A0A931C715_9ACTN/15-172             .......................IDLYRTDDYVFHGRADLYPLLRGVF............REALGRPLDDAL..FALSFH...QVS..........DQR.....DNGGHPEMVSLRPSHSYLTIRILVGD...RLIYRHPHSVREVVAKPLQRLLAAD.....FPDEDH.......WGYALAG.PGLEKIALE.RPAPRL................EGTIDVRPRRGR...TSRLNLEEVAEPEPP---par.............................
A0A918IEF0_9ACTN/12-170             .......................VLLYKGTSFDLIGKMTLSSLMVEGL............RRDLPDGEPDEP..LIMHLRy.vRRP..........DPR.....LVDGPRTIHNLRSQIGRLGVIVSQGG...ETVIDREYPVRELLGPVLQHVVQQL.....DPDEQV.......WGFCIDH.PSLSGLALG.RSTPEV................EGTMDLNLRESR...-RSFTVRKVAEPPVPG--id..............................
A0A545AZJ8_9ACTN/5-164              .......................VEIYRTDDYLSVGRVPLVPLLQHFF............EPMLGRSLAGCR..FHLLFL...PVA..........EDG.....VLPGPPELVNLRGSHGYVQVRIVQAGgddTVLYRHPHPVSEVIAGPLQEQLAKA.....APAETH.......WGFGVVA.PGFD-GRMV.RPTPAV................DGVIGIRTSGTV...TPLFHLEEVAEPDPPLA-t...............................
A0A944L2R0_9ACTN/9-166              .......................VELFRSDDYVRAGRLPLLPLLRSVL............EPMVGQSLEGAT..IELSFL...PLT..........DRA.....PVRGTPSVINLRGSHGYVKVRIVRGD...TVLYQHPHALREIVGRPLQELLGER.....LPEETH.......WGFGIRG.PGLEKVALV.RPKPVA................ANRVEIAVGGPR...RRLFGIEEVPEPEPPVA-t...............................
A0A101P0U1_9ACTN/12-170             .......................VLLYKGTSFDLVGKMTLSSLMVEAL............RRDLPGGDQEEP..LIMHLRy.vRRP..........DPR.....LVDGPRTIHNLRSQIGRLGVIVSQGG...ETLIDREYPVRELLGPVLQHVVQQL.....DADEQV.......WGFCIDH.PSLSGLALG.RSTPEV................EGTMDLNLRESR...-RSFTVRKVAEPPVP---gvd.............................
A0A5N8XGB6_9ACTN/6-163              .......................VELFRSDDYVSAGQVPLLPLLRRVF............EPLIGQSLAGTR..FELLFL...PVA..........DSR.....RLSGPPSLVNLRSSHGYVQVRILHNG...TVVYQHPHSVREIIARPLQQLLVDR.....GPQESH.......WGFGVRG.PGLDRIALV.RPVPDV................VNQVDISRGGRG...ARLFHVEEVRSPEPPHA-d...............................
A0A1G7X3Y9_9ACTN/5-174              .......................IELYKGRRRTYYGRLVLQQVLFEALndahpgllpraeDVEKSERSERPR..FVLHFH...DAE..........DTG.....RIPGEPEVTNVRADFGHLDLRVLVGG...AVVHERHYSVSELLGDVLAKLLSRI.....DPDERV.......WGFAIRH.PALGAMARS.RRAPEV................EGAVDIDLKETR...NLPFTVQRIEERQDAVD-p...............................
A0A5M3XQP3_9ACTN/5-167              .......................VELFRGGDQTPVRRVPLEPVLRRFF............ESQLDQALSGAV..IQLLFL...PEP..........EPGpavslENTGGFSVANLRPRYGHVQVRVLLND...ELLYQHPHPVSELLGRALRDTLREL.....APDERH.......WGFGLHG.PNFDHGPLV.RPVPEM................EHGVHIEVGAHR...GRIFDLEELPPPDPP---lst.............................
A0A926L2S6_9ACTN/5-162              .......................IELFQGESRQLVRTEPLIPLLRPVF............AEETARHQGRPR..FVLMLR...NDP..........GPD.....IYEGDPHLTNLRADFGYIHVAIHMEG...RVVYQKPYSVNSLVGPVLARMARQI.....APEERH.......WAFRIAGlPTHEDGA-E.RLPPVV................DGTDDIDVSRSA...RLSFGIRPAAEPQMPLL-d...............................
A0A7W7V988_9ACTN/12-170             .......................VLLYKSTSFDYVGKISLSSLMVEAL............RRELEEGDPEDQ..LIMHLRy.vRRP..........DPR.....LADGPRTIHNLRSQIGRLGVIVSRAG...ETVVDREYPVRELLGPVLQHVVQQI.....DPDEQV.......WGFCLDH.PSLGGLSLG.RSTPEV................EGTMDLNLRESR...-RSFTVRKVAEPPVP---gvd.............................
A0A1V1NV25_9BACT/4-142              ....aapflnqllgdlwktaepp-------------------------............------------..VAILMS..iPGE..........DNN.....L-YGDHPLTYHTDAIGYIQLRIQYQG...RMQYYHPHSIVEVLSPGLHQWLSEI.....PNPPKA.......VGYRIIT.PNIGQLVR-.QATPIP................KGVTEITPYAPG..eQPAFRIRPIP--------ppspepn.........................
A0A8T4F1U9_9ACTN/6-175              .......................VDVYRIDDFTKQDSVPLTGLLRSAL............EPLLGESLAGAR..FNLVFL...PVP..........DLG.....VLDGHPPLINLRSSHGYLNVRVVLGG...LLVYQHPHSVREVVARPLQRLLAARgadgrTPGSRHqgsgdggWGFGISG.PGLDHISLV.RPKPVL................PGSVEISVGTRR...RALFHVEELPEPEPRV--tt..............................
A0A8J3VLP2_9ACTN/12-169             .......................VELYKGESLTLHSRLPLADLVYVGL............LEEMGLSAKTLN..YRVVAV...NIA..........DEQ.....ELTGEPELINVRHDFGHLIISGSQAN...GIPYKRWFPIRELLAPTVRKIAHEL.....DPVEKL.......WGYCLAS.PVISQFPIA.RPVPVV................QGTMEIHTGDTT...QSRFRVKRSVEPTLPE--fd..............................
A0A2U3A626_9ACTN/5-174              .......................IELFQGESRQLVRTEPLIALLKPAF............AAETAPFKGRPR..FVLMLR...NDPgpdtyepdthDTD.....TYDGDLHLTNLRADFGYIHVAIHMEG...RVVYQKPYSVNSLVGPVLARLAREI.....APEERR.......WAFRIAGlPSPEDGESA.QRLPPV...............vDGTDDIDVSRST...RLPFGIRPAVEPEIPLL-d...............................
A0A1H2AII6_9ACTN/5-158              .......................VELFTAPDYTYGERHALVPLLRDAL............RPVLGAVVDRAG..FRLSLQ...PVD..........DEG.....TLDGTPSLVNLRPGHGYVIVTAVADG...RIVYRHPHTVRELVGRPLQRHLARS.....HPDVAH.......WGYGLAG.PGLEKLAFV.KPVPAV................EGQVEITAGRRR...----GITRLEELPEPEP-d...............................
A0A252E5P0_9NOSO/9-178              .......................IELYRGADRKFFGTMPFLPIVQESL............ESLLGRSLLLKS..ILVILL...QVP..........EEP.....LPIESPVVENLVPDFGYTYIKVYQGN...FLIYQHPHRLYDVLTKNLRTKLSNQ.....YPEEIW.......WGFRVDI.PGMPQISAF.RLNPRVstlh.......ptparEGNAEIIPYPHPhgeKPKFQIRRLAEAEPPLKT................................
A0A917VLG8_9ACTN/1-162              .......................--MFRGADLVPAGRVPLEPVLRRFF............ESQLDQTLSGAR..IQLLFLp.eREPs.......psGSF.....ETTGEFSIANLRPRYGHVQVRVKLDG...EVLYQHPHPVSELLGRALRDTLAEL.....APDERR.......WGFGLHG.PNFERGPLV.RPAPQM................EHGVQIEVGAHP...R--GRVFQLEELPPP---dpplrt..........................
#=GC seq_cons                       .......................l-La+usshshhu+hsLhsLLppsh............cp.Lupshtpsp..htLhht...ths..........Dst.....hhsGsssltNLRssaGalpVplhtsG...cllYp+PasVpELlG.sLpchLppl.....sP-Ept.......WGFslss.Pulsplsls.RssPtl................-Gsh-lsstpst...t.sFplcclsEP.sP...s...............................
//