GenomeNet

Database: Pfam
Entry: hEGF
LinkDB: hEGF
Original site: hEGF 
#=GF ID   hEGF
#=GF AC   PF12661.10
#=GF DE   Human growth factor-like EGF
#=GF AU   Wouters M;0000-0002-2121-912X
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Wouters M
#=GF GA   29.30 13.60;
#=GF TC   29.30 13.60;
#=GF NC   29.20 13.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   EGF-like_domain
#=GF CL   CL0001
#=GF RN   [1]
#=GF RM   15772310
#=GF RT   Evolution of distinct EGF domains with specific functions.
#=GF RA   Wouters MA, Rigoutsos I, Chu CK, Feng LL, Sparrow DB, Dunwoodie
#=GF RA   SL;
#=GF RL   Protein Sci. 2005;14:1091-1103.
#=GF DR   INTERPRO; IPR013032;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   hEGF, or human growth factor-like EGF, domains have six
#=GF CC   conserved residues disulfide-bonded into the characteristic
#=GF CC   'ababcc' pattern. They are involved in growth and proliferation
#=GF CC   of cells, in proteins of the Notch/Delta pathway, neurogulin and
#=GF CC   selectins. hEGFs are also found in mosaic proteins with
#=GF CC   four-disulfide laminin EGFs such as aggrecan and perlecan.  The
#=GF CC   core fold of the EGF domain consists of two small beta-hairpins
#=GF CC   packed against each other. Two major structural variants have
#=GF CC   been identified based on the structural context of the
#=GF CC   C-terminal Cys residue of disulfide 'c' in the C-terminal
#=GF CC   hairpin: hEGFs and cEGFs. In hEGFs the C-terminal thiol resides
#=GF CC   in the beta-turn, resulting in shorter loop-lengths between the
#=GF CC   Cys residues of disulfide 'c', typically C[8-9]XC.  These
#=GF CC   shorter loop-lengths are also typical of the four-disulfide EGF
#=GF CC   domains, laminin ad integrin.  Tandem hEGF domains have six
#=GF CC   linking residues between terminal cysteines of adjacent domains.
#=GF CC   hEGF domains may or may not bind calcium in the linker region.
#=GF CC   hEGF domains with the consensus motif CXD4X[F,Y]XCXC are
#=GF CC   hydroxylated exclusively in the Asp residue.
#=GF SQ   32688
#=GS A0A091GRD6_9AVES/213-232      AC A0A091GRD6.1
#=GS A0A670IX74_PODMU/1716-1737    AC A0A670IX74.1
#=GS A0A671XGG1_SPAAU/1037-1058    AC A0A671XGG1.1
#=GS A0A094ME43_ANTCR/106-125      AC A0A094ME43.1
#=GS A0A6J1Z950_ACIJB/230-252      AC A0A6J1Z950.1
#=GS A0A1U7QN09_MESAU/712-731      AC A0A1U7QN09.1
#=GS I3IXB2_ORENI/1127-1148        AC I3IXB2.2
#=GS A0A1S3RWT6_SALSA/579-598      AC A0A1S3RWT6.1
#=GS A0A482V7B2_9CUCU/1153-1175    AC A0A482V7B2.1
#=GS G1RNU3_NOMLE/587-606          AC G1RNU3.1
#=GS A0A671XA16_SPAAU/982-1003     AC A0A671XA16.1
#=GS A0A3Q2E3S5_CYPVA/1211-1230    AC A0A3Q2E3S5.1
#=GS A0A5C6PKL3_9TELE/518-538      AC A0A5C6PKL3.1
#=GS L5LEN4_MYODS/350-370          AC L5LEN4.1
#=GS G1RP75_NOMLE/438-458          AC G1RP75.2
#=GS A0A5A9PDD6_9TELE/1193-1213    AC A0A5A9PDD6.1
#=GS A0A2I3SKB0_PANTR/550-571      AC A0A2I3SKB0.1
#=GS A0A7N6BC99_ANATE/1353-1374    AC A0A7N6BC99.1
#=GS A0A6I9J9T9_CHRAS/218-236      AC A0A6I9J9T9.1
#=GS A0A6J0V9Z2_9SAUR/45-64        AC A0A6J0V9Z2.1
#=GS A0A2R2MP02_LINUN/225-243      AC A0A2R2MP02.1
#=GS A0A4W5RSI3_9TELE/382-400      AC A0A4W5RSI3.1
#=GS A0A482XAW2_LAOST/84-104       AC A0A482XAW2.1
#=GS A0A091KEJ0_COLST/282-301      AC A0A091KEJ0.1
#=GS A0A673MPJ3_9TELE/337-357      AC A0A673MPJ3.1
#=GS U3JG63_FICAL/498-521          AC U3JG63.1
#=GS A0A1L8F124_XENLA/574-594      AC A0A1L8F124.1
#=GS A0A5F9CWP7_RABIT/191-210      AC A0A5F9CWP7.1
#=GS A0A663FJK3_AQUCH/413-432      AC A0A663FJK3.1
#=GS A0A183IVM6_9BILA/271-290      AC A0A183IVM6.1
#=GS A0A4X2MBG7_VOMUR/1597-1618    AC A0A4X2MBG7.1
#=GS A0A4W3GD48_CALMI/460-480      AC A0A4W3GD48.1
#=GS A0A3Q7VAW9_URSAR/858-878      AC A0A3Q7VAW9.1
#=GS A0A091RHQ5_9GRUI/38-57        AC A0A091RHQ5.1
#=GS G3I363_CRIGR/553-572          AC G3I363.1
#=GS A0A663FI88_AQUCH/146-168      AC A0A663FI88.1
#=GS A0A0B1PKM7_9BILA/421-440      AC A0A0B1PKM7.1
#=GS A0A673Z8Z6_SALTR/252-272      AC A0A673Z8Z6.1
#=GS A0A2K6P7J9_RHIRO/490-511      AC A0A2K6P7J9.1
#=GS A0A3Q1C7D2_AMPOC/1141-1161    AC A0A3Q1C7D2.1
#=GS A0A4W3K1G4_CALMI/414-433      AC A0A4W3K1G4.1
#=GS A0A0V0VR41_9BILA/430-451      AC A0A0V0VR41.1
#=GS A0A2K5EJA2_AOTNA/1153-1174    AC A0A2K5EJA2.1
#=GS A0A1D2NMB5_ORCCI/2165-2185    AC A0A1D2NMB5.1
#=GS A0A2K5JCB4_COLAP/119-140      AC A0A2K5JCB4.1
#=GS G3U507_LOXAF/587-606          AC G3U507.1
#=GS A7T4U6_NEMVE/53-73            AC A7T4U6.1
#=GS A0A3P8RY22_AMPPE/590-610      AC A0A3P8RY22.1
#=GS A0A6Q2XWY1_ESOLU/258-276      AC A0A6Q2XWY1.1
#=GS A0A1S3I663_LINUN/498-519      AC A0A1S3I663.1
#=GS A0A2K5P823_CERAT/240-259      AC A0A2K5P823.1
#=GS A0A6P7YQI8_9AMPH/641-662      AC A0A6P7YQI8.1
#=GS A0A673VI23_SURSU/128-146      AC A0A673VI23.1
#=GS H2ZJD0_CIOSA/2085-2105        AC H2ZJD0.1
#=GS A0A3Q3FA92_9LABR/124-145      AC A0A3Q3FA92.1
#=GS A0A7M7NQV9_STRPU/2444-2465    AC A0A7M7NQV9.1
#=GS A0A6J0Z998_ODOVR/230-250      AC A0A6J0Z998.1
#=GS H3ADH5_LATCH/308-327          AC H3ADH5.1
#=GS A0A6J2Y7L4_SITOR/382-403      AC A0A6J2Y7L4.1
#=GS A0A091LPV2_CATAU/122-140      AC A0A091LPV2.1
#=GS A0A6P7X8C9_9AMPH/498-519      AC A0A6P7X8C9.1
#=GS A0A665WKK8_ECHNA/999-1020     AC A0A665WKK8.1
#=GS A0A5N5M235_PANHP/1355-1373    AC A0A5N5M235.1
#=GS A0A2I3SKP8_PANTR/753-773      AC A0A2I3SKP8.1
#=GS A0A7M7SYB2_STRPU/153-174      AC A0A7M7SYB2.1
#=GS A0A6J3RZN5_TURTR/191-215      AC A0A6J3RZN5.1
#=GS A0A2A3EE67_APICC/187-205      AC A0A2A3EE67.1
#=GS A0A3Q3B989_KRYMA/782-803      AC A0A3Q3B989.1
#=GS A0A3Q3N234_9TELE/916-937      AC A0A3Q3N234.1
#=GS A0A6P6F4B2_OCTDE/443-460      AC A0A6P6F4B2.1
#=GS A0A2R2MKN1_LINUN/249-270      AC A0A2R2MKN1.1
#=GS A0A7R5L4P2_9PASS/159-178      AC A0A7R5L4P2.1
#=GS A0A384D633_URSMA/377-397      AC A0A384D633.1
#=GS A0A3Q1HZA4_9TELE/392-418      AC A0A3Q1HZA4.1
#=GS H3DMI5_TETNG/638-658          AC H3DMI5.1
#=GS A0A5N4DV71_CAMDR/344-364      AC A0A5N4DV71.1
#=GS H0VU21_CAVPO/214-236          AC H0VU21.2
#=GS A0A653DW76_CALMS/717-736      AC A0A653DW76.1
#=GS A0A672RRF1_SINGR/1290-1311    AC A0A672RRF1.1
#=GS A0A7N8WLK5_9TELE/480-500      AC A0A7N8WLK5.1
#=GS A0A6J0THE5_9SAUR/1276-1297    AC A0A6J0THE5.1
#=GS A0A6J3JMK5_SAPAP/108-132      AC A0A6J3JMK5.1
#=GS A0A6J1Y7H0_ACIJB/1358-1379    AC A0A6J1Y7H0.1
#=GS A0A3Q3T0I1_9TELE/579-598      AC A0A3Q3T0I1.2
#=GS G5C0B3_HETGA/1297-1318        AC G5C0B3.1
#=GS A0A437C3B5_ORYJA/1269-1288    AC A0A437C3B5.1
#=GS A0A674MI26_TAKRU/216-235      AC A0A674MI26.1
#=GS A0A6Q2WY11_ESOLU/526-546      AC A0A6Q2WY11.1
#=GS A0A6Q2WX93_ESOLU/884-905      AC A0A6Q2WX93.1
#=GS A0A3Q2FUD3_CYPVA/607-627      AC A0A3Q2FUD3.1
#=GS A0A0V1NJJ2_9BILA/2456-2473    AC A0A0V1NJJ2.1
#=GS A0A6I9NRU0_9TELE/271-291      AC A0A6I9NRU0.1
#=GS A0A2I3LN94_PAPAN/337-357      AC A0A2I3LN94.1
#=GS A0A6P4ZNI1_BRABE/1380-1401    AC A0A6P4ZNI1.1
#=GS A0A093NL74_PYGAD/197-216      AC A0A093NL74.1
#=GS A0A2Y9G049_TRIMA/136-160      AC A0A2Y9G049.1
#=GS A0A4W2ET14_BOBOX/712-731      AC A0A4W2ET14.1
#=GS A0A2I4CBY6_9TELE/1346-1367    AC A0A2I4CBY6.1
#=GS A0A673CKU8_9TELE/111-133      AC A0A673CKU8.1
#=GS A0A5N4E0G7_CAMDR/392-413      AC A0A5N4E0G7.1
#=GS A0A6P4ZI20_BRABE/1170-1187    AC A0A6P4ZI20.1
#=GS A0A1S2ZYB7_ERIEU/1346-1367    AC A0A1S2ZYB7.1
#=GS A0A091LVX2_CARIC/1184-1205    AC A0A091LVX2.1
#=GS A0A665WCP8_ECHNA/870-892      AC A0A665WCP8.1
#=GS A0A672V1W7_STRHB/531-551      AC A0A672V1W7.1
#=GS A0A6P6RDK0_CARAU/587-606      AC A0A6P6RDK0.1
#=GS A0A016TTU3_9BILA/91-112       AC A0A016TTU3.1
#=GS A0A663DQW6_AQUCH/492-511      AC A0A663DQW6.1
#=GS A0A6P3X539_DINQU/1080-1099    AC A0A6P3X539.1
#=GS A0A3B5QGZ8_XIPMA/1349-1370    AC A0A3B5QGZ8.1
#=GS U3I4Q8_ANAPP/111-130          AC U3I4Q8.2
#=GS A0A7E6D7W2_9CHIR/1363-1384    AC A0A7E6D7W2.1
#=GS A0A665X8D2_ECHNA/324-345      AC A0A665X8D2.1
#=GS A0A7N4PUS1_SARHA/239-258      AC A0A7N4PUS1.1
#=GS A0A4Z2GJY4_9TELE/205-229      AC A0A4Z2GJY4.1
#=GS A0A6Q8JR05_HUMAN/3949-3967    AC A0A6Q8JR05.1
#=GS A0A3Q7S4K8_VULVU/501-520      AC A0A3Q7S4K8.1
#=GS E2RQ32_CANLF/587-606          AC E2RQ32.2
#=GS A0A3Q7PKS3_CALUR/718-737      AC A0A3Q7PKS3.1
#=GS A0A673HJG1_9TELE/1653-1674    AC A0A673HJG1.1
#=GS A0A6G0I0C3_LARCR/588-607      AC A0A6G0I0C3.1
#=GS M7AX84_CHEMY/862-883          AC M7AX84.1
#=GS A0A3Q7Y9M4_CICAR/201-224      AC A0A3Q7Y9M4.1
#=GS A0A671RIY6_9TELE/1196-1217    AC A0A671RIY6.1
#=GS A0A6I8QIT8_XENTR/239-258      AC A0A6I8QIT8.1
#=GS A0A4W6CGE9_LATCA/587-606      AC A0A4W6CGE9.1
#=GS A0A5N5LJ66_PANHP/249-267      AC A0A5N5LJ66.1
#=GS A0A016V0J4_9BILA/306-326      AC A0A016V0J4.1
#=GS A0A669CTB3_ORENI/1383-1404    AC A0A669CTB3.1
#=GS A0A5F8GBW2_MONDO/416-436      AC A0A5F8GBW2.1
#=GS A0A672PTS1_SINGR/87-105       AC A0A672PTS1.1
#=GS A0A7M7T0D9_STRPU/2651-2672    AC A0A7M7T0D9.1
#=GS A0A6P4ZI20_BRABE/1298-1315    AC A0A6P4ZI20.1
#=GS A0A498SFX1_ACAVI/1712-1731    AC A0A498SFX1.1
#=GS F7EN18_CALJA/444-465          AC F7EN18.2
#=GS A0A3Q3VII6_MOLML/421-440      AC A0A3Q3VII6.1
#=GS I3IZM4_ORENI/370-390          AC I3IZM4.2
#=GS G1MTP6_MELGA/966-987          AC G1MTP6.2
#=GS A0A4U1F092_MONMO/497-518      AC A0A4U1F092.1
#=GS A0A2Y9GPS0_NEOSC/790-809      AC A0A2Y9GPS0.1
#=GS A0A212CH58_CEREH/15-35        AC A0A212CH58.1
#=GS A0A7M7P2P3_STRPU/2651-2672    AC A0A7M7P2P3.1
#=GS A0A2K5LWR7_CERAT/191-210      AC A0A2K5LWR7.1
#=GS A0A671VD06_SPAAU/244-263      AC A0A671VD06.1
#=GS A0A4W2DAJ5_BOBOX/264-284      AC A0A4W2DAJ5.1
#=GS A0A5E4MQT0_9HEMI/1370-1391    AC A0A5E4MQT0.1
#=GS A0A2K6FG13_PROCO/998-1019     AC A0A2K6FG13.1
#=GS A0A671DRC6_RHIFE/469-489      AC A0A671DRC6.1
#=GS A0A0B1ST76_OESDE/73-96        AC A0A0B1ST76.1
#=GS A0A671PSI6_9TELE/882-901      AC A0A671PSI6.1
#=GS A0A4W5MV84_9TELE/818-839      AC A0A4W5MV84.1
#=GS A0A6P7WWX4_9AMPH/240-259      AC A0A6P7WWX4.1
#=GS A0A7M7NSR9_STRPU/405-426      AC A0A7M7NSR9.1
#=GS A0A2K5C3D5_AOTNA/215-236      AC A0A2K5C3D5.1
#=GS A0A2I4CBF8_9TELE/66-91        AC A0A2I4CBF8.1
#=GS A0A7N5KIS2_AILME/1294-1315    AC A0A7N5KIS2.1
#=GS A0A3Q4GY47_NEOBR/811-832      AC A0A3Q4GY47.1
#=GS W5KTW9_ASTMX/308-330          AC W5KTW9.2
#=GS A0A1U7TJS1_CARSF/874-894      AC A0A1U7TJS1.1
#=GS A0A6P6RDH0_CARAU/240-259      AC A0A6P6RDH0.1
#=GS A0A2K6TGE2_SAIBB/714-735      AC A0A2K6TGE2.1
#=GS A0A286XPG4_CAVPO/128-146      AC A0A286XPG4.1
#=GS A0A4W5MRR9_9TELE/576-597      AC A0A4W5MRR9.1
#=GS A0A2I3T0D0_PANTR/967-988      AC A0A2I3T0D0.1
#=GS A0A498MW06_LABRO/569-588      AC A0A498MW06.1
#=GS A0A2K5R3E6_CEBIM/250-267      AC A0A2K5R3E6.1
#=GS A0A1S3K9X3_LINUN/201-218      AC A0A1S3K9X3.1
#=GS A0A5F8HC26_MONDO/458-477      AC A0A5F8HC26.1
#=GS A0A2K5D309_AOTNA/955-974      AC A0A2K5D309.1
#=GS A0A1S3JYS6_LINUN/865-884      AC A0A1S3JYS6.1
#=GS A0A087SWK1_STEMI/295-322      AC A0A087SWK1.1
#=GS A0A674EYE1_SALTR/420-441      AC A0A674EYE1.1
#=GS A0A5F8GUM3_MONDO/240-259      AC A0A5F8GUM3.1
#=GS A0A182GKJ6_AEDAL/268-287      AC A0A182GKJ6.1
#=GS A0A7M7NU54_STRPU/12190-12211  AC A0A7M7NU54.1
#=GS G1MH13_AILME/230-252          AC G1MH13.1
#=GS A0A670HTQ1_PODMU/765-786      AC A0A670HTQ1.1
#=GS A0A6P3EQZ5_OCTDE/142-166      AC A0A6P3EQZ5.1
#=GS A0A669P0K1_PHACC/1213-1234    AC A0A669P0K1.1
#=GS A0A6J1Z7S4_ACIJB/704-725      AC A0A6J1Z7S4.1
#=GS A0A6P8FLC5_CLUHA/1451-1472    AC A0A6P8FLC5.1
#=GS A0A671XFN2_SPAAU/286-306      AC A0A671XFN2.1
#=GS A0A673CWT3_9TELE/67-86        AC A0A673CWT3.1
#=GS A0A1S3G813_DIPOR/796-817      AC A0A1S3G813.1
#=GS A0A0V0UAN7_9BILA/798-817      AC A0A0V0UAN7.1
#=GS A0A1S3M8T1_SALSA/116-133      AC A0A1S3M8T1.1
#=GS A0A4W3K6L8_CALMI/1010-1029    AC A0A4W3K6L8.1
#=GS A0A2K5QRZ6_CEBIM/358-379      AC A0A2K5QRZ6.1
#=GS A0A669F3F1_ORENI/810-830      AC A0A669F3F1.1
#=GS A0A2K6FD62_PROCO/18-38        AC A0A2K6FD62.1
#=GS A0A452FPD8_CAPHI/230-252      AC A0A452FPD8.1
#=GS A0A6J2W3X9_CHACN/472-491      AC A0A6J2W3X9.1
#=GS G3S172_GORGO/627-647          AC G3S172.2
#=GS A0A2U9C2T0_SCOMX/664-683      AC A0A2U9C2T0.1
#=GS A0A3Q2VQC4_HAPBU/576-596      AC A0A3Q2VQC4.1
#=GS A0A6J8CWL3_MYTCO/719-737      AC A0A6J8CWL3.1
#=GS A0A6P4YHY2_BRABE/554-576      AC A0A6P4YHY2.1
#=GS H2P962_PONAB/541-562          AC H2P962.2
#=GS A0A6P4YS43_BRABE/1505-1525    AC A0A6P4YS43.1
#=GS H2Z4I6_CIOSA/386-405          AC H2Z4I6.1
#=GS A0A091MBK8_CATAU/1480-1501    AC A0A091MBK8.1
#=GS A0A2I3RZT2_PANTR/1183-1202    AC A0A2I3RZT2.1
#=GS A0A6Q2XM40_ESOLU/414-435      AC A0A6Q2XM40.1
#=GS A0A6P8QDL3_GEOSA/197-216      AC A0A6P8QDL3.1
#=GS C3Z444_BRAFL/1-12             AC C3Z444.1
#=GS A0A6P9BD55_PANGU/197-216      AC A0A6P9BD55.1
#=GS B4HGM0_DROSE/916-934          AC B4HGM0.1
#=GS A0A670KA18_PODMU/1223-1244    AC A0A670KA18.1
#=GS A0A4W2ESP0_BOBOX/243-262      AC A0A4W2ESP0.1
#=GS A0A6P8PEG4_GEOSA/202-221      AC A0A6P8PEG4.1
#=GS A0A7N8WQ47_9TELE/1461-1482    AC A0A7N8WQ47.1
#=GS A0A672IYS4_SALFA/460-481      AC A0A672IYS4.1
#=GS M7BQF9_CHEMY/69-87            AC M7BQF9.1
#=GS A0A673ZYL4_SALTR/332-352      AC A0A673ZYL4.1
#=GS A0A1S3JXS2_LINUN/865-884      AC A0A1S3JXS2.1
#=GS A0A3B1J0H0_ASTMX/593-612      AC A0A3B1J0H0.1
#=GS A0A0B1S0J2_OESDE/11-32        AC A0A0B1S0J2.1
#=GS A0A094LSN6_PODCR/420-445      AC A0A094LSN6.1
#=GS A0A6J3H603_SAPAP/474-494      AC A0A6J3H603.1
#=GS A0A452IWB7_9SAUR/343-362      AC A0A452IWB7.1
#=GS A0A6P4YMN9_BRABE/1234-1251    AC A0A6P4YMN9.1
#=GS A0A5N4CLI7_CAMDR/618-638      AC A0A5N4CLI7.1
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#=GS A0A423T4J2_PENVA/992-1010     AC A0A423T4J2.1
#=GS A0A2G8K4Z6_STIJA/478-498      AC A0A2G8K4Z6.1
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#=GS H3AS41_LATCH/191-210          AC H3AS41.1
#=GS A0A6P7SPC1_OCTVU/1279-1300    AC A0A6P7SPC1.1
#=GS A0A1V4KH05_PATFA/2296-2318    AC A0A1V4KH05.1
#=GS A0A2K5CYC7_AOTNA/505-525      AC A0A2K5CYC7.1
#=GS A0A1V9WZR9_9ACAR/74-93        AC A0A1V9WZR9.1
#=GS A0A6J3H2T2_SAPAP/31-53        AC A0A6J3H2T2.1
#=GS A0A669EEF2_ORENI/196-215      AC A0A669EEF2.1
#=GS A0A6J3HH77_SAPAP/1336-1357    AC A0A6J3HH77.1
#=GS A0A663FB27_AQUCH/1222-1243    AC A0A663FB27.1
#=GS A0A6J2UVT1_CHACN/989-1010     AC A0A6J2UVT1.1
#=GS A0A5F4D1F0_CANLF/113-130      AC A0A5F4D1F0.1
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#=GS A0A5F8GGU8_MONDO/240-259      AC A0A5F8GGU8.1
#=GS B3RZ28_TRIAD/709-730          AC B3RZ28.1
#=GS H3DIG5_TETNG/755-773          AC H3DIG5.1
#=GS H2Y6J9_CIOSA/671-691          AC H2Y6J9.1
#=GS A0A3Q7XA17_URSAR/1051-1069    AC A0A3Q7XA17.1
#=GS H2Z914_CIOSA/257-278          AC H2Z914.1
#=GS A0A504Z9I7_FASGI/43-65        AC A0A504Z9I7.1
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#=GS A0A7N9AUT4_9TELE/40-63        AC A0A7N9AUT4.1
#=GS A0A2K6DXX7_MACNE/1027-1048    AC A0A2K6DXX7.1
#=GS A0A670HUW2_PODMU/923-942      AC A0A670HUW2.1
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#=GS A0A663MTJ4_ATHCN/588-607      AC A0A663MTJ4.1
#=GS NOTC2_RAT/729-749             AC Q9QW30.1
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#=GS A0A2P8YLM3_BLAGE/546-566      AC A0A2P8YLM3.1
#=GS A0A091ILZ2_EGRGA/42-63        AC A0A091ILZ2.1
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#=GS A0A0D8XT76_DICVI/324-345      AC A0A0D8XT76.1
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#=GS A0A3P7VBR3_RODNA/236-258      AC A0A3P7VBR3.1
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#=GS A0A369SDH9_9METZ/589-611      AC A0A369SDH9.1
#=GS U3IDR2_ANAPP/1150-1169        AC U3IDR2.2
#=GS A0A1S3WNB3_ERIEU/1341-1362    AC A0A1S3WNB3.1
#=GS NOTC1_RAT/687-708             AC Q07008.3
#=GS A0A672YWY4_9TELE/580-599      AC A0A672YWY4.1
#=GS A0A182GTP7_AEDAL/654-675      AC A0A182GTP7.1
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#=GS A0A3P9AFF5_ESOLU/477-496      AC A0A3P9AFF5.1
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#=GS A0A6P4ZPG3_BRABE/2-22         AC A0A6P4ZPG3.1
#=GS A0A4W4E424_ELEEL/24-44        AC A0A4W4E424.1
#=GS A0A1U8DXR7_ALLSI/128-145      AC A0A1U8DXR7.2
#=GS A0A401RI47_CHIPU/70-88        AC A0A401RI47.1
#=GS A0A287BJI4_PIG/490-511        AC A0A287BJI4.1
#=GS A0A4U5V4W0_COLLU/1555-1573    AC A0A4U5V4W0.1
#=GS A0A7M7NSL6_STRPU/130-150      AC A0A7M7NSL6.1
#=GS A0A6P7N929_BETSP/66-91        AC A0A6P7N929.1
#=GS A0A6P4YS43_BRABE/2073-2094    AC A0A6P4YS43.1
#=GS A0A3Q2VV88_HAPBU/339-364      AC A0A3Q2VV88.1
#=GS A0A672HYS7_SALFA/101-118      AC A0A672HYS7.1
#=GS A0A2I3LYV8_PAPAN/647-667      AC A0A2I3LYV8.1
#=GS H3DIG5_TETNG/568-586          AC H3DIG5.1
#=GS A0A5F9DR43_RABIT/191-210      AC A0A5F9DR43.1
#=GS A0A433U9M4_ELYCH/1002-1022    AC A0A433U9M4.1
#=GS A0A3Q2V1X5_HAPBU/1349-1370    AC A0A3Q2V1X5.1
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#=GS A0A0D8XXR6_DICVI/214-232      AC A0A0D8XXR6.1
#=GS A0A0B4LIS1_DROME/360-381      AC A0A0B4LIS1.1
#=GS SVEP1_HUMAN/1316-1337         AC Q4LDE5.3
#=GS A0A669DUW4_ORENI/22-47        AC A0A669DUW4.1
#=GS A0A6I8MYS3_ORNAN/1343-1364    AC A0A6I8MYS3.1
#=GS A0A6P8PPR9_GEOSA/587-606      AC A0A6P8PPR9.1
#=GS A0A6I9KA06_CHRAS/829-849      AC A0A6I9KA06.1
#=GS A0A6P8SFG4_GEOSA/529-554      AC A0A6P8SFG4.1
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#=GS F7FIC2_MACMU/233-254          AC F7FIC2.3
#=GS A0A7M7T3R9_STRPU/1900-1921    AC A0A7M7T3R9.1
#=GS A0A6G1BA77_CROCR/805-825      AC A0A6G1BA77.1
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#=GS A0A672UV68_STRHB/458-479      AC A0A672UV68.1
#=GS L9KNC3_TUPCH/797-818          AC L9KNC3.1
#=GS A0A6J2A0N3_ACIJB/452-471      AC A0A6J2A0N3.1
#=GS A0A452SNH7_URSAM/1285-1303    AC A0A452SNH7.1
#=GS A0A672RRM4_SINGR/988-1009     AC A0A672RRM4.1
#=GS G1TB95_RABIT/1314-1335        AC G1TB95.2
#=GS A0A663MR27_ATHCN/373-392      AC A0A663MR27.1
#=GS A0A3P9BQ05_9CICH/1222-1242    AC A0A3P9BQ05.1
#=GS A0A091UBK9_PHORB/547-562      AC A0A091UBK9.1
#=GS A0A6J1S5V8_FRAOC/1277-1296    AC A0A6J1S5V8.1
#=GS A0A087R0I2_APTFO/415-434      AC A0A087R0I2.1
#=GS A0A452GYX7_9SAUR/234-254      AC A0A452GYX7.1
#=GS A0A6Q2X448_ESOLU/436-455      AC A0A6Q2X448.1
#=GS A0A3Q0FRV1_ALLSI/333-353      AC A0A3Q0FRV1.1
#=GS A0A6G0UXB8_9BILA/687-708      AC A0A6G0UXB8.1
#=GS A0A6J2VSV2_CHACN/491-512      AC A0A6J2VSV2.1
#=GS A0A3Q1BSD2_AMPOC/565-584      AC A0A3Q1BSD2.1
#=GS G1SSN4_RABIT/401-422          AC G1SSN4.2
#=GS A0A674AE78_SALTR/1091-1112    AC A0A674AE78.1
#=GS A0A3Q1JJY6_ANATE/564-585      AC A0A3Q1JJY6.1
#=GS A0A7M7NNB8_STRPU/380-402      AC A0A7M7NNB8.1
#=GS A0A2A9M671_9APIC/297-318      AC A0A2A9M671.1
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#=GS A0A667Y6K3_9TELE/1053-1074    AC A0A667Y6K3.1
#=GS G5EFX3_CAEEL/1579-1598        AC G5EFX3.1
#=GS A0A099ZLG7_TINGU/280-299      AC A0A099ZLG7.1
#=GS A0A663FH31_AQUCH/489-509      AC A0A663FH31.1
#=GS A0A6P4ZTK0_BRABE/377-398      AC A0A6P4ZTK0.1
#=GS A0A6J8D2A5_MYTCO/286-307      AC A0A6J8D2A5.1
#=GS A0A2Y9DIM7_TRIMA/219-240      AC A0A2Y9DIM7.1
#=GS A0A096MYN1_PAPAN/3949-3967    AC A0A096MYN1.2
#=GS A0A2Y9IR35_ENHLU/250-267      AC A0A2Y9IR35.1
#=GS A0A1S3T051_SALSA/1135-1156    AC A0A1S3T051.1
#=GS A0A669QCE1_PHACC/472-491      AC A0A669QCE1.1
#=GS A0A6J2W792_CHACN/403-424      AC A0A6J2W792.1
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#=GS A0A0N4V6D5_ENTVE/1808-1829    AC A0A0N4V6D5.2
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#=GS A0A402E5S7_9SAUR/1009-1033    AC A0A402E5S7.1
#=GS EYS_PONAB/742-763             AC Q5R6R1.3
#=GS Q6MG89_RAT/735-754            AC Q6MG89.1
#=GS A0A6I8SAQ2_XENTR/580-598      AC A0A6I8SAQ2.2
#=GS A0A553QKM8_9TELE/31-56        AC A0A553QKM8.1
#=GS A0A3Q3N5U2_9TELE/2579-2601    AC A0A3Q3N5U2.2
#=GS A0A6P7XG77_9AMPH/456-477      AC A0A6P7XG77.1
#=GS A0A151M7V9_ALLMI/631-650      AC A0A151M7V9.1
#=GS A0A6P8TNY7_GYMAC/1048-1069    AC A0A6P8TNY7.1
#=GS A0A1S3T051_SALSA/1016-1035    AC A0A1S3T051.1
#=GS A0A6P4ZI31_BRABE/1586-1603    AC A0A6P4ZI31.1
#=GS A0A1U7TCJ8_CARSF/673-694      AC A0A1U7TCJ8.1
#=GS A0A1S3A1I0_ERIEU/197-216      AC A0A1S3A1I0.1
#=GS A0A2R2MRQ5_LINUN/324-343      AC A0A2R2MRQ5.1
#=GS A0A087SX30_STEMI/878-899      AC A0A087SX30.1
#=GS A0A670ZAV2_PSETE/996-1016     AC A0A670ZAV2.1
#=GS F7DBB2_MACMU/128-146          AC F7DBB2.3
#=GS A0A6I8NA78_ORNAN/1321-1342    AC A0A6I8NA78.1
#=GS I3IZM4_ORENI/847-868          AC I3IZM4.2
#=GS A0A0G2KQ62_DANRE/628-647      AC A0A0G2KQ62.2
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#=GS A0A6P4ZMA4_BRABE/1298-1315    AC A0A6P4ZMA4.1
#=GS A0A093EW19_TYTAL/10-28        AC A0A093EW19.1
#=GS A0A669BWK8_ORENI/22-47        AC A0A669BWK8.1
#=GS A0A3Q4HUB9_NEOBR/496-515      AC A0A3Q4HUB9.1
#=GS A0A7N6A3S7_ANATE/1308-1329    AC A0A7N6A3S7.1
#=GS A0A6P4ZFG8_BRABE/342-360      AC A0A6P4ZFG8.1
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#=GS A0A3P9PDI3_POERE/1281-1302    AC A0A3P9PDI3.1
#=GS A0A7E6DA23_9CHIR/1156-1177    AC A0A7E6DA23.1
#=GS A0A3P7R095_DRAME/159-183      AC A0A3P7R095.1
#=GS A0A2K5LFT6_CERAT/998-1017     AC A0A2K5LFT6.1
#=GS A0A1L8F3L0_XENLA/1330-1350    AC A0A1L8F3L0.1
#=GS G5C3I8_HETGA/322-343          AC G5C3I8.1
#=GS A0A671KVF6_9TELE/458-479      AC A0A671KVF6.1
#=GS A0A671UPH1_SPAAU/3480-3498    AC A0A671UPH1.1
#=GS A0A7M7PV58_STRPU/688-708      AC A0A7M7PV58.1
#=GS A0A212CAQ2_CEREH/366-387      AC A0A212CAQ2.1
#=GS A0A6P4Z4L1_BRABE/1997-2017    AC A0A6P4Z4L1.1
#=GS A0A2G9SJ04_LITCT/138-155      AC A0A2G9SJ04.1
#=GS A0A151ND57_ALLMI/843-867      AC A0A151ND57.1
#=GS A0A369SDH9_9METZ/512-534      AC A0A369SDH9.1
#=GS D6WKS5_TRICA/269-288          AC D6WKS5.1
#=GS A0A3P8YS80_ESOLU/238-257      AC A0A3P8YS80.2
#=GS A0A673MPJ3_9TELE/594-614      AC A0A673MPJ3.1
#=GS E1BNM8_BOVIN/218-236          AC E1BNM8.2
#=GS A0A2K6K3L6_RHIBE/438-459      AC A0A2K6K3L6.1
#=GS M3ZJK7_XIPMA/31-50            AC M3ZJK7.1
#=GS A0A663MSU4_ATHCN/501-520      AC A0A663MSU4.1
#=GS A0A6I8QCW2_XENTR/1243-1264    AC A0A6I8QCW2.2
#=GS V4AX71_LOTGI/245-266          AC V4AX71.1
#=GS A0A672QDN8_SINGR/573-595      AC A0A672QDN8.1
#=GS A0A4W5KSJ7_9TELE/47-66        AC A0A4W5KSJ7.1
#=GS H2MIG7_ORYLA/239-258          AC H2MIG7.2
#=GS A0A674IEV8_TERCA/932-953      AC A0A674IEV8.1
#=GS C3XTS3_BRAFL/136-154          AC C3XTS3.1
#=GS A0A340WRL6_LIPVE/829-849      AC A0A340WRL6.1
#=GS A0A6J1ZWN4_ACIJB/936-956      AC A0A6J1ZWN4.1
#=GS A0A0V0ZGY9_9BILA/1165-1184    AC A0A0V0ZGY9.1
#=GS A0A4W5MJA5_9TELE/485-506      AC A0A4W5MJA5.1
#=GS A0A6P4Z2F0_BRABE/1842-1859    AC A0A6P4Z2F0.1
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#=GS A0A401SN56_CHIPU/1015-1036    AC A0A401SN56.1
#=GS A0A2I3SWV9_PANTR/1199-1216    AC A0A2I3SWV9.1
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#=GS A0A6A5FRF0_PERFL/1412-1433    AC A0A6A5FRF0.1
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#=GS A0A151J8H0_9HYME/257-281      AC A0A151J8H0.1
#=GS A0A6J0VRA0_ODOVR/1105-1126    AC A0A6J0VRA0.1
#=GS A0A0D9S5Z9_CHLSB/347-367      AC A0A0D9S5Z9.1
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#=GS A0A485NNF6_LYNPA/581-600      AC A0A485NNF6.1
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#=GS A0A6J1PJ96_9HYME/201-223      AC A0A6J1PJ96.1
#=GS A0A218V1X8_9PASE/718-737      AC A0A218V1X8.1
#=GS A0A672IFL9_SALFA/844-861      AC A0A672IFL9.1
#=GS A0A1S3M6M8_SALSA/1263-1283    AC A0A1S3M6M8.1
#=GS A0A5E4CZ87_MARMO/230-252      AC A0A5E4CZ87.1
#=GS A0A663FGW7_AQUCH/980-1001     AC A0A663FGW7.1
#=GS A0A6J2HT79_9PASS/233-255      AC A0A6J2HT79.1
#=GS A0A3P9N290_POERE/420-441      AC A0A3P9N290.1
#=GS F1PK98_CANLF/712-731          AC F1PK98.2
#=GS A0A3Q2U5D4_CHICK/511-531      AC A0A3Q2U5D4.1
#=GS A0A2B4S2T8_STYPI/2261-2281    AC A0A2B4S2T8.1
#=GS A0A2Y9JI73_ENHLU/1105-1126    AC A0A2Y9JI73.1
#=GS A0A7R5KRX4_9PASS/1274-1296    AC A0A7R5KRX4.1
#=GS A0A6F9B8Y2_9TELE/329-348      AC A0A6F9B8Y2.1
#=GS A0A6J1Y8P0_ACIJB/262-283      AC A0A6J1Y8P0.1
#=GS A0A2Y9H3G2_NEOSC/645-664      AC A0A2Y9H3G2.1
#=GS B3MT39_DROAN/373-394          AC B3MT39.1
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#=GS A0A672H9N7_SALFA/939-960      AC A0A672H9N7.1
#=GS A0A6I9LI21_PERMB/562-583      AC A0A6I9LI21.1
#=GS A0A3Q2HZF7_HORSE/854-874      AC A0A3Q2HZF7.1
#=GS A0A2I3MQ69_PAPAN/226-248      AC A0A2I3MQ69.1
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#=GS B3RZ27_TRIAD/467-489          AC B3RZ27.1
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#=GS F6UL72_HORSE/467-487          AC F6UL72.2
#=GS A0A0Q9X0I4_DROMO/1859-1880    AC A0A0Q9X0I4.1
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#=GS A0A674A2F2_SALTR/527-547      AC A0A674A2F2.1
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#=GS A0A2K5IWX7_COLAP/362-383      AC A0A2K5IWX7.1
#=GS A0A093NSN2_PYGAD/989-1010     AC A0A093NSN2.1
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#=GS A0A1Y1N5H2_PHOPY/1004-1025    AC A0A1Y1N5H2.1
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#=GS A0A6P8P351_GEOSA/935-954      AC A0A6P8P351.1
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