GenomeNet

Database: Pfam
Entry: zf-C3HC4_4
LinkDB: zf-C3HC4_4
Original site: zf-C3HC4_4 
#=GF ID   zf-C3HC4_4
#=GF AC   PF15227.9
#=GF DE   zinc finger of C3HC4-type, RING
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   manual
#=GF GA   30.00 30.00;
#=GF TC   30.00 30.00;
#=GF NC   29.90 29.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0229
#=GF RN   [1]
#=GF RM   18656177
#=GF RT   Evolutionary Forces Shape the Human RFPL1,2,3 Genes toward a
#=GF RT   Role in Neocortex Development. 
#=GF RA   Bonnefont J, Nikolaev SI, Perrier AL, Guo S, Cartier L, Sorce S,
#=GF RA   Laforge T, Aubry L, Khaitovich P, Peschanski M, Antonarakis SE,
#=GF RA   Krause KH; 
#=GF RL   Am J Hum Genet. 2008; [Epub ahead of print]
#=GF RN   [2]
#=GF RM   20725088
#=GF RT   Primate-specific RFPL1 gene controls cell-cycle progression
#=GF RT   through cyclin B1/Cdc2 degradation.
#=GF RA   Bonnefont J, Laforge T, Plastre O, Beck B, Sorce S, Dehay C,
#=GF RA   Krause KH;
#=GF RL   Cell Death Differ. 2011;18:293-303.
#=GF RN   [3]
#=GF RM   19489725
#=GF RT   RING domain E3 ubiquitin ligases.
#=GF RA   Deshaies RJ, Joazeiro CA;
#=GF RL   Annu Rev Biochem. 2009;78:399-434.
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is a family of primate-specific Ret finger protein-like
#=GF CC   (RFPL) zinc-fingers of the C3HC4 type. Ret finger protein-like
#=GF CC   proteins are primate-specific target genes of Pax6, a key
#=GF CC   transcription factor for pancreas, eye and neocortex development
#=GF CC   [1]. This domain is likely to be DNA-binding [2]. This
#=GF CC   zinc-finger domain together with the RDM domain, Pfam:PF11002,
#=GF CC   forms a large zinc-finger structure of the RING/U-Box
#=GF CC   superfamily. RING-containing proteins are known to exert an E3
#=GF CC   ubiquitin protein ligase activity with the zinc-finger structure
#=GF CC   being mandatory for binding to the E2 ubiquitin-conjugating
#=GF CC   enzyme [3].
#=GF SQ   14272
#=GS A0A2K5EYS0_AOTNA/5-46       AC A0A2K5EYS0.1
#=GS A0A2Y9M571_DELLE/20-57      AC A0A2Y9M571.1
#=GS A0A6I9NNZ2_9TELE/17-59      AC A0A6I9NNZ2.1
#=GS W5NKK9_LEPOC/13-55          AC W5NKK9.1
#=GS A0A3Q2VF28_HAPBU/14-53      AC A0A3Q2VF28.1
#=GS A0A087XQF7_POEFO/15-57      AC A0A087XQF7.2
#=GS A0A674B3F1_SALTR/15-57      AC A0A674B3F1.1
#=GS A0A5F9C9S7_RABIT/53-93      AC A0A5F9C9S7.1
#=GS A0A402EC72_9SAUR/16-56      AC A0A402EC72.1
#=GS A0A3Q2XA32_HAPBU/15-58      AC A0A3Q2XA32.1
#=GS A0A1S3KQS1_SALSA/15-57      AC A0A1S3KQS1.1
#=GS A0A3Q3FFR9_9LABR/11-53      AC A0A3Q3FFR9.1
#=GS A0A6P8F012_CLUHA/36-78      AC A0A6P8F012.1
#=GS A0A672GHE4_SALFA/18-59      AC A0A672GHE4.1
#=GS A0A3B1KCA3_ASTMX/16-58      AC A0A3B1KCA3.1
#=GS A0A671WMZ8_SPAAU/39-81      AC A0A671WMZ8.1
#=GS G1M8X7_AILME/41-81          AC G1M8X7.2
#=GS A0A485MY05_LYNPA/16-62      AC A0A485MY05.1
#=GS A0A6I9P9W1_9TELE/11-52      AC A0A6I9P9W1.1
#=GS A0A669D3F7_ORENI/162-204    AC A0A669D3F7.1
#=GS A0A1U7Q8R5_MESAU/16-62      AC A0A1U7Q8R5.1
#=GS A0A3P8XY29_ESOLU/18-60      AC A0A3P8XY29.2
#=GS A0A4W3HAG7_CALMI/16-55      AC A0A4W3HAG7.1
#=GS G3HVW2_CRIGR/29-69          AC G3HVW2.1
#=GS A0A673ZG80_SALTR/14-56      AC A0A673ZG80.1
#=GS A0A0J0XY01_9TREE/227-262    AC A0A0J0XY01.1
#=GS A0A668W1D1_OREAU/25-65      AC A0A668W1D1.1
#=GS A0A2K5LIJ5_CERAT/16-56      AC A0A2K5LIJ5.1
#=GS A0A3B5QSF9_XIPMA/13-55      AC A0A3B5QSF9.1
#=GS A0A4W5QNH8_9TELE/12-55      AC A0A4W5QNH8.1
#=GS A0A3Q1M0C3_BOVIN/20-57      AC A0A3Q1M0C3.1
#=GS F6U3C4_HORSE/16-56          AC F6U3C4.2
#=GS A0A6P6LZB6_CARAU/14-56      AC A0A6P6LZB6.1
#=GS A0A7N8XVX0_9TELE/140-182    AC A0A7N8XVX0.1
#=GS M3YF67_MUSPF/15-59          AC M3YF67.1
#=GS A0A2I4CGZ8_9TELE/15-57      AC A0A2I4CGZ8.1
#=GS A0A3P9DDM9_9CICH/13-55      AC A0A3P9DDM9.1
#=GS A0A096NED6_PAPAN/20-56      AC A0A096NED6.1
#=GS A0A6P6JNY7_CARAU/13-55      AC A0A6P6JNY7.1
#=GS A0A2Y9S6F3_PHYMC/5-45       AC A0A2Y9S6F3.1
#=GS A0A4W5M316_9TELE/15-58      AC A0A4W5M316.1
#=GS A0A3Q7XAI0_URSAR/20-57      AC A0A3Q7XAI0.1
#=GS A0A5N5JGZ1_PANHP/15-57      AC A0A5N5JGZ1.1
#=GS A0A3Q1CPL6_AMPOC/124-164    AC A0A3Q1CPL6.1
#=GS A0A2R8Q9S3_DANRE/15-57      AC A0A2R8Q9S3.1
#=GS A0A340XEH5_LIPVE/15-59      AC A0A340XEH5.1
#=GS A0A3Q1FUY3_9TELE/72-117     AC A0A3Q1FUY3.1
#=GS A0A3Q1FN26_9TELE/10-53      AC A0A3Q1FN26.1
#=GS A0A0G2K6C7_RAT/15-58        AC A0A0G2K6C7.1
#=GS G0MUS8_CAEBE/56-88          AC G0MUS8.1
#=GS A0A3Q7QK00_CALUR/29-69      AC A0A3Q7QK00.1
#=GS H2NEX8_PONAB/15-55          AC H2NEX8.1
#=GS A0A2R8Q4R4_DANRE/16-58      AC A0A2R8Q4R4.1
#=GS A0A0B5H7I8_CHICK/22-62      AC A0A0B5H7I8.1
#=GS A0A2K5YG76_MANLE/16-56      AC A0A2K5YG76.1
#=GS A0A2U3WYP1_ODORO/12-52      AC A0A2U3WYP1.1
#=GS A0A6J1VHP0_9SAUR/14-54      AC A0A6J1VHP0.1
#=GS TRI62_HUMAN/11-53           AC Q9BVG3.1
#=GS A0A3Q4BY14_MOLML/18-59      AC A0A3Q4BY14.1
#=GS A0A673AU52_9TELE/15-57      AC A0A673AU52.1
#=GS A0A2K6UNS0_SAIBB/15-59      AC A0A2K6UNS0.1
#=GS A0A1A6HD13_NEOLE/10-49      AC A0A1A6HD13.1
#=GS A0A4W5Q7X3_9TELE/12-54      AC A0A4W5Q7X3.1
#=GS A0A3N0XSA7_ANAGA/13-55      AC A0A3N0XSA7.1
#=GS A0A4W6FLD3_LATCA/68-110     AC A0A4W6FLD3.1
#=GS D6RG73_MOUSE/34-73          AC D6RG73.1
#=GS A0A667ZDS5_9TELE/15-57      AC A0A667ZDS5.1
#=GS A0A2K6RAF6_RHIRO/34-73      AC A0A2K6RAF6.1
#=GS A0A6J0V0U4_9SAUR/16-56      AC A0A6J0V0U4.1
#=GS A0A3B1KEW7_ASTMX/15-57      AC A0A3B1KEW7.1
#=GS A0A6P6BX62_PTEVA/16-60      AC A0A6P6BX62.1
#=GS A0A6J0SHE9_9SAUR/16-58      AC A0A6J0SHE9.1
#=GS A0A2K5ZN94_MANLE/15-59      AC A0A2K5ZN94.1
#=GS A0A4W4EVM4_ELEEL/15-57      AC A0A4W4EVM4.1
#=GS B0S648_DANRE/14-56          AC B0S648.1
#=GS A0A3Q3E0J8_9LABR/22-64      AC A0A3Q3E0J8.1
#=GS A0A4W2CLF3_BOBOX/15-59      AC A0A4W2CLF3.1
#=GS A0A669EIY0_ORENI/231-273    AC A0A669EIY0.1
#=GS A0A060YME2_ONCMY/10-52      AC A0A060YME2.1
#=GS A0A6P8UBF3_GYMAC/108-150    AC A0A6P8UBF3.1
#=GS A0A6I9MUY9_9TELE/14-56      AC A0A6I9MUY9.1
#=GS A0A6Q2ZIY1_ESOLU/10-52      AC A0A6Q2ZIY1.1
#=GS A0A3Q3F662_9LABR/196-238    AC A0A3Q3F662.1
#=GS A0A6P8FEX1_CLUHA/14-56      AC A0A6P8FEX1.1
#=GS A0A493TF15_ANAPP/21-61      AC A0A493TF15.1
#=GS A0A6J0SEE5_9SAUR/13-54      AC A0A6J0SEE5.1
#=GS A0A3Q3N756_9LABR/12-50      AC A0A3Q3N756.1
#=GS A0A485PP68_LYNPA/16-56      AC A0A485PP68.1
#=GS F1PIC3_CANLF/13-57          AC F1PIC3.2
#=GS W5MHR4_LEPOC/15-54          AC W5MHR4.1
#=GS A0A4W3H818_CALMI/16-55      AC A0A4W3H818.1
#=GS A0A2Y9IHH9_ENHLU/20-57      AC A0A2Y9IHH9.1
#=GS A0A665XG91_ECHNA/14-56      AC A0A665XG91.1
#=GS A0A2K6MTC3_RHIBE/16-62      AC A0A2K6MTC3.1
#=GS A0A6P3QNU5_PTEVA/16-56      AC A0A6P3QNU5.1
#=GS A0A3Q3WCS2_MOLML/14-56      AC A0A3Q3WCS2.1
#=GS H2QCL9_PANTR/25-66          AC H2QCL9.1
#=GS A0A6P3FPP3_OCTDE/16-60      AC A0A6P3FPP3.1
#=GS A0A6Q2X151_ESOLU/10-52      AC A0A6Q2X151.1
#=GS A0A6P7ILE2_9TELE/18-59      AC A0A6P7ILE2.1
#=GS A0A5N5PRU8_PANHP/23-63      AC A0A5N5PRU8.1
#=GS A0A3Q2ZKL9_KRYMA/15-57      AC A0A3Q2ZKL9.1
#=GS A0A2G9S1X7_LITCT/61-103     AC A0A2G9S1X7.1
#=GS A0A6J2UW30_CHACN/372-411    AC A0A6J2UW30.1
#=GS A0A6P7XYE9_9AMPH/16-56      AC A0A6P7XYE9.1
#=GS A0A455CB04_PHYMC/34-73      AC A0A455CB04.1
#=GS A0A6P6DMW1_OCTDE/13-53      AC A0A6P6DMW1.1
#=GS A0A4W6CSZ1_LATCA/15-57      AC A0A4W6CSZ1.1
#=GS A0A6P8T006_GYMAC/15-57      AC A0A6P8T006.1
#=GS A0A6J0SE75_9SAUR/18-62      AC A0A6J0SE75.1
#=GS G1T3X6_RABIT/16-60          AC G1T3X6.3
#=GS A0A2Y9RMJ8_TRIMA/225-265    AC A0A2Y9RMJ8.1
#=GS A0A673Y2M3_SALTR/15-57      AC A0A673Y2M3.1
#=GS A0A2F0BMX3_ESCRO/16-56      AC A0A2F0BMX3.1
#=GS A0A2U3V8M0_TURTR/15-59      AC A0A2U3V8M0.1
#=GS A0A6J2VN09_CHACN/15-57      AC A0A6J2VN09.1
#=GS A0A5J5CQJ5_9PERO/1333-1374  AC A0A5J5CQJ5.1
#=GS A0A669DBY0_ORENI/15-57      AC A0A669DBY0.1
#=GS A0A3Q3F3J2_9LABR/15-57      AC A0A3Q3F3J2.1
#=GS L5LZ31_MYODS/16-60          AC L5LZ31.1
#=GS TRIML_MOUSE/22-62           AC Q8BVP1.1
#=GS L8HQV3_9CETA/16-55          AC L8HQV3.1
#=GS A0A5F9DA22_RABIT/15-55      AC A0A5F9DA22.1
#=GS H2ZRN2_LATCH/15-56          AC H2ZRN2.1
#=GS A0A3P9D487_9CICH/16-60      AC A0A3P9D487.1
#=GS A0A4W4HJE7_ELEEL/12-51      AC A0A4W4HJE7.1
#=GS A0A6I9KRK8_CHRAS/29-69      AC A0A6I9KRK8.1
#=GS A0A5F5PUT7_HORSE/34-73      AC A0A5F5PUT7.1
#=GS A0A2K6P8I4_RHIRO/11-53      AC A0A2K6P8I4.1
#=GS A0A6P6MK26_CARAU/13-55      AC A0A6P6MK26.1
#=GS A0A673MHV8_9TELE/15-57      AC A0A673MHV8.1
#=GS A0A401SMB5_CHIPU/15-57      AC A0A401SMB5.1
#=GS A0A671X416_SPAAU/212-254    AC A0A671X416.1
#=GS A0A674BLS4_SALTR/15-57      AC A0A674BLS4.1
#=GS A0A6P7N5D7_BETSP/46-85      AC A0A6P7N5D7.1
#=GS A0A3P8RXN9_AMPPE/79-121     AC A0A3P8RXN9.1
#=GS A0A672RZY6_SINGR/15-57      AC A0A672RZY6.1
#=GS A0A2K6MF34_RHIBE/29-69      AC A0A2K6MF34.1
#=GS A0A4W5P3K1_9TELE/15-57      AC A0A4W5P3K1.1
#=GS A0A6P8WK16_GYMAC/306-348    AC A0A6P8WK16.1
#=GS A0A7F8K5E0_DELLE/9-57       AC A0A7F8K5E0.1
#=GS A0A3B5PY98_XIPMA/20-62      AC A0A3B5PY98.1
#=GS A0A4W2D971_BOBOX/145-185    AC A0A4W2D971.1
#=GS A0A672LS61_SINGR/12-54      AC A0A672LS61.1
#=GS A0A671DXF0_RHIFE/41-81      AC A0A671DXF0.1
#=GS A0A2K6K2G8_RHIBE/16-56      AC A0A2K6K2G8.1
#=GS A0A7M7P7V0_STRPU/380-422    AC A0A7M7P7V0.1
#=GS A0A0L7M561_PLAF4/202-239    AC A0A0L7M561.1
#=GS A0A667Z244_9TELE/12-54      AC A0A667Z244.1
#=GS A0A498MVP3_LABRO/38-83      AC A0A498MVP3.1
#=GS A0A671ER67_RHIFE/9-57       AC A0A671ER67.1
#=GS A0A1S3AQ74_ERIEU/16-56      AC A0A1S3AQ74.1
#=GS A0A1S2ZCQ1_ERIEU/16-56      AC A0A1S2ZCQ1.1
#=GS A0A6J2V896_CHACN/15-57      AC A0A6J2V896.1
#=GS A0A6P7MPX7_BETSP/10-53      AC A0A6P7MPX7.1
#=GS A0A6F9A5M8_9TELE/255-297    AC A0A6F9A5M8.1
#=GS A0A2K6B8G0_MACNE/16-56      AC A0A2K6B8G0.1
#=GS A0A2K6RBE0_RHIRO/40-81      AC A0A2K6RBE0.1
#=GS A0A444UZR1_ACIRT/14-55      AC A0A444UZR1.1
#=GS A0A6P6R1L6_CARAU/13-55      AC A0A6P6R1L6.1
#=GS A0A093C9X3_9AVES/13-45      AC A0A093C9X3.1
#=GS A0A087XSQ5_POEFO/28-70      AC A0A087XSQ5.2
#=GS A0A6J2W104_CHACN/14-53      AC A0A6J2W104.1
#=GS A0A3P9Q6U3_POERE/13-55      AC A0A3P9Q6U3.1
#=GS A0A3P8XHR5_ESOLU/12-54      AC A0A3P8XHR5.2
#=GS A0A6P8VRC3_GYMAC/15-54      AC A0A6P8VRC3.1
#=GS A0A2Y9MDG9_DELLE/16-56      AC A0A2Y9MDG9.1
#=GS A0A669EVL7_ORENI/14-55      AC A0A669EVL7.1
#=GS A0A3P9BD56_9CICH/14-53      AC A0A3P9BD56.1
#=GS A0A663DM66_AQUCH/15-62      AC A0A663DM66.1
#=GS A0A096M4L6_POEFO/13-55      AC A0A096M4L6.1
#=GS A0A6P8VXM7_GYMAC/15-57      AC A0A6P8VXM7.1
#=GS TRI61_HUMAN/16-56           AC Q5EBN2.1
#=GS A0A669D5F9_ORENI/124-166    AC A0A669D5F9.1
#=GS A0A671NTY4_9TELE/15-57      AC A0A671NTY4.1
#=GS B0S540_DANRE/15-57          AC B0S540.1
#=GS A0A671W2W6_SPAAU/259-301    AC A0A671W2W6.1
#=GS A0A1U7QPF8_MESAU/20-57      AC A0A1U7QPF8.1
#=GS A0A4W5L2Z5_9TELE/15-57      AC A0A4W5L2Z5.1
#=GS A0A2K5Q882_CEBIM/15-58      AC A0A2K5Q882.1
#=GS A0A087XMY6_POEFO/16-57      AC A0A087XMY6.1
#=GS A0A2Y9J2G7_ENHLU/22-62      AC A0A2Y9J2G7.1
#=GS A0A340Y6V0_LIPVE/11-52      AC A0A340Y6V0.1
#=GS A0A3Q7NH17_CALUR/12-52      AC A0A3Q7NH17.1
#=GS A0A6J3HAY4_SAPAP/20-57      AC A0A6J3HAY4.1
#=GS A0A673LH97_9TELE/13-55      AC A0A673LH97.1
#=GS A0A6P8T733_GYMAC/54-96      AC A0A6P8T733.1
#=GS A0A3Q7QB52_CALUR/41-81      AC A0A3Q7QB52.1
#=GS A0A3N0YJ12_ANAGA/15-57      AC A0A3N0YJ12.1
#=GS A0A6P5CZP4_BOSIN/15-59      AC A0A6P5CZP4.1
#=GS A0A3P8W765_CYNSE/15-57      AC A0A3P8W765.1
#=GS A0A437DMA8_ORYJA/15-56      AC A0A437DMA8.1
#=GS A0A4W4HMN3_ELEEL/16-54      AC A0A4W4HMN3.1
#=GS A0A7I4EYX5_PHYPA/474-511    AC A0A7I4EYX5.1
#=GS F2ULM9_SALR5/328-374        AC F2ULM9.1
#=GS A0A2K5VME0_MACFA/15-59      AC A0A2K5VME0.2
#=GS A0A671NJT6_9TELE/9-51       AC A0A671NJT6.1
#=GS A0A672JCM0_SALFA/15-57      AC A0A672JCM0.1
#=GS A0A7N9AS16_9TELE/119-159    AC A0A7N9AS16.1
#=GS A0A4W5LCM0_9TELE/15-56      AC A0A4W5LCM0.1
#=GS A0A1S3N8W9_SALSA/12-51      AC A0A1S3N8W9.1
#=GS A0A667ZAG2_9TELE/16-56      AC A0A667ZAG2.1
#=GS A0A2K5KFU6_COLAP/16-56      AC A0A2K5KFU6.1
#=GS A0A671Z4D1_SPAAU/15-57      AC A0A671Z4D1.1
#=GS A0A6J3E2L7_AYTFU/36-68      AC A0A6J3E2L7.1
#=GS A0A194PDM7_PAPXU/36-69      AC A0A194PDM7.1
#=GS A0A7I4A2E6_PHYPA/474-511    AC A0A7I4A2E6.1
#=GS A0A5F7ZAF8_MACMU/16-62      AC A0A5F7ZAF8.1
#=GS A0A2I2Y3S2_GORGO/16-56      AC A0A2I2Y3S2.1
#=GS A0A3Q2X3P0_HAPBU/52-97      AC A0A3Q2X3P0.1
#=GS A0A803JHB1_XENTR/12-55      AC A0A803JHB1.1
#=GS W5N4N5_LEPOC/14-53          AC W5N4N5.1
#=GS A0A2B4R8B2_STYPI/938-980    AC A0A2B4R8B2.1
#=GS A0A669EC04_ORENI/15-54      AC A0A669EC04.1
#=GS A0A3P9MZ84_POERE/19-61      AC A0A3P9MZ84.1
#=GS A0A1S3KQZ5_SALSA/15-57      AC A0A1S3KQZ5.1
#=GS A0A673TVM2_SURSU/15-59      AC A0A673TVM2.1
#=GS A0A6P6NTF9_CARAU/13-56      AC A0A6P6NTF9.1
#=GS A0A4W6CM43_LATCA/15-56      AC A0A4W6CM43.1
#=GS A0A2P6QQF6_ROSCH/762-797    AC A0A2P6QQF6.1
#=GS A0A2U9BMI5_SCOMX/41-80      AC A0A2U9BMI5.1
#=GS A0A6P6L890_CARAU/13-55      AC A0A6P6L890.1
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#=GS A0A3P8VAP2_CYNSE/16-57      AC A0A3P8VAP2.1
#=GS A0A3P8TZF0_AMPPE/15-57      AC A0A3P8TZF0.1
#=GS A0A674BMY0_SALTR/15-57      AC A0A674BMY0.1
#=GS A0A6P7YM22_9AMPH/15-58      AC A0A6P7YM22.1
#=GS A0A087X872_POEFO/13-55      AC A0A087X872.2
#=GS G1P4Q9_MYOLU/34-73          AC G1P4Q9.1
#=GS A0A674K218_TERCA/16-62      AC A0A674K218.1
#=GS A0A672LRU6_SINGR/15-57      AC A0A672LRU6.1
#=GS A0A3Q0CAS2_MESAU/15-58      AC A0A3Q0CAS2.1
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#=GS A0A1L8I214_XENLA/12-54      AC A0A1L8I214.1
#=GS K7F427_PELSI/16-56          AC K7F427.1
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#=GS A0A402FQZ1_9SAUR/32-76      AC A0A402FQZ1.1
#=GS A0A663LPS1_ATHCN/15-62      AC A0A663LPS1.1
#=GS A0A2P4T277_BAMTH/20-63      AC A0A2P4T277.1
#=GS A0A669BYZ6_ORENI/9-51       AC A0A669BYZ6.1
#=GS A0A4U5UER2_COLLU/15-57      AC A0A4U5UER2.1
#=GS A0A6J1VXN6_9SAUR/20-64      AC A0A6J1VXN6.1
#=GS A0A401REC3_CHIPU/12-54      AC A0A401REC3.1
#=GS A0A6J0V922_9SAUR/11-52      AC A0A6J0V922.1
#=GS A0A444UQA5_ACIRT/15-57      AC A0A444UQA5.1
#=GS A0A2K5N1H5_CERAT/16-56      AC A0A2K5N1H5.1
#=GS A0A6P8FWU6_CLUHA/10-52      AC A0A6P8FWU6.1
#=GS G3NAF7_GASAC/13-52          AC G3NAF7.1
#=GS A0A4W4G2U2_ELEEL/13-47      AC A0A4W4G2U2.1
#=GS A0A0D9R6B9_CHLSB/16-62      AC A0A0D9R6B9.1
#=GS A0A2K5EID0_AOTNA/29-58      AC A0A2K5EID0.1
#=GS A0A6J3GLV7_SAPAP/11-52      AC A0A6J3GLV7.1
#=GS A0A3Q3FMN8_9LABR/19-61      AC A0A3Q3FMN8.1
#=GS A0A4W4G7K4_ELEEL/15-57      AC A0A4W4G7K4.1
#=GS A0A673ZU02_SALTR/15-57      AC A0A673ZU02.1
#=GS A0A3Q3FPU1_9LABR/11-50      AC A0A3Q3FPU1.1
#=GS A0A6I8PYA4_XENTR/16-47      AC A0A6I8PYA4.2
#=GS A0A2Y9DTH2_TRIMA/37-77      AC A0A2Y9DTH2.1
#=GS A0A6P6QPE4_CARAU/13-55      AC A0A6P6QPE4.1
#=GS A0A6P3QUQ2_PTEVA/16-56      AC A0A6P3QUQ2.1
#=GS A0A6J2VAP3_CHACN/10-56      AC A0A6J2VAP3.1
#=GS G3SE48_GORGO/15-59          AC G3SE48.2
#=GS A0A669EXD7_ORENI/15-57      AC A0A669EXD7.1
#=GS A0A669B4T9_ORENI/188-230    AC A0A669B4T9.1
#=GS A0A096M099_POEFO/15-57      AC A0A096M099.1
#=GS A0A1S3AF54_ERIEU/16-56      AC A0A1S3AF54.1
#=GS A0A671U088_SPAAU/10-53      AC A0A671U088.1
#=GS A0A6P8GG40_CLUHA/10-64      AC A0A6P8GG40.1
#=GS A0A3Q7WPB8_URSAR/20-57      AC A0A3Q7WPB8.1
#=GS A0A6P8FF58_CLUHA/12-54      AC A0A6P8FF58.1
#=GS L5JP03_PTEAL/11-52          AC L5JP03.1
#=GS I3KZP9_ORENI/15-57          AC I3KZP9.2
#=GS A0A3P9DTC6_9CICH/15-57      AC A0A3P9DTC6.1
#=GS A0A6P6ICS4_PUMCO/15-55      AC A0A6P6ICS4.1
#=GS A0A668S4A8_OREAU/25-64      AC A0A668S4A8.1
#=GS A0A671DUJ8_RHIFE/16-56      AC A0A671DUJ8.1
#=GS A0A671NLJ4_9TELE/13-55      AC A0A671NLJ4.1
#=GS A0A4W6G216_LATCA/198-240    AC A0A4W6G216.1
#=GS A0A671Y6J0_SPAAU/97-139     AC A0A671Y6J0.1
#=GS A0A5N4DPD5_CAMDR/15-59      AC A0A5N4DPD5.1
#=GS A0A2K5NIB5_CERAT/14-56      AC A0A2K5NIB5.1
#=GS M3VZL4_FELCA/29-80          AC M3VZL4.1
#=GS A0A3P8TCP3_AMPPE/124-164    AC A0A3P8TCP3.1
#=GS A0A3Q1M2K4_BOVIN/16-55      AC A0A3Q1M2K4.1
#=GS M7AVJ6_CHEMY/216-263        AC M7AVJ6.1
#=GS A0A6P5LXC9_PHACI/16-56      AC A0A6P5LXC9.1
#=GS A0A6I9HY79_VICPA/11-53      AC A0A6I9HY79.1
#=GS A0A4W3GZ42_CALMI/12-51      AC A0A4W3GZ42.1
#=GS A0A4W3I1E4_CALMI/16-55      AC A0A4W3I1E4.1
#=GS A0A1L8F3T6_XENLA/16-59      AC A0A1L8F3T6.1
#=GS A0A341BZA9_NEOAA/16-56      AC A0A341BZA9.1
#=GS A0A3Q7N9S3_CALUR/20-57      AC A0A3Q7N9S3.1
#=GS A0A670HWP1_PODMU/15-61      AC A0A670HWP1.1
#=GS A0A6J3A759_VICPA/20-57      AC A0A6J3A759.1
#=GS S4R7E7_PETMA/14-48          AC S4R7E7.1
#=GS A0A0G2K3D6_RAT/16-55        AC A0A0G2K3D6.1
#=GS A0A3Q3MW32_9TELE/95-137     AC A0A3Q3MW32.2
#=GS A0A669DES7_ORENI/138-180    AC A0A669DES7.1
#=GS A0A673MSD7_9TELE/13-57      AC A0A673MSD7.1
#=GS A0A6P8F1W4_CLUHA/191-233    AC A0A6P8F1W4.1
#=GS A0A402FYM2_9SAUR/658-699    AC A0A402FYM2.1
#=GS A0A452GPC4_9SAUR/8-48       AC A0A452GPC4.1
#=GS A0A401RE54_CHIPU/15-57      AC A0A401RE54.1
#=GS A0A2K5DEH6_AOTNA/15-58      AC A0A2K5DEH6.1
#=GS A0A4D9DG51_9SAUR/16-60      AC A0A4D9DG51.1
#=GS A0A6J0CTC6_PERMB/62-105     AC A0A6J0CTC6.1
#=GS A0A672LQX1_SINGR/15-57      AC A0A672LQX1.1
#=GS F7INH3_CALJA/16-60          AC F7INH3.2
#=GS A0A4W6CCR1_LATCA/15-55      AC A0A4W6CCR1.1
#=GS A0A667YSP1_9TELE/15-57      AC A0A667YSP1.1
#=GS A0A3Q3MAS8_9TELE/13-55      AC A0A3Q3MAS8.2
#=GS A0A6G0HNG1_LARCR/15-55      AC A0A6G0HNG1.1
#=GS A0A7E6E4X8_9CHIR/15-59      AC A0A7E6E4X8.1
#=GS A0A7E4V0D8_PANRE/7-40       AC A0A7E4V0D8.1
#=GS H2PUE3_PONAB/20-57          AC H2PUE3.2
#=GS A0A674ISH5_TERCA/16-56      AC A0A674ISH5.1
#=GS F7HDR2_MACMU/34-73          AC F7HDR2.1
#=GS M3ZUR3_XIPMA/12-54          AC M3ZUR3.2
#=GS A0A6I9ZI18_ACIJB/41-81      AC A0A6I9ZI18.1
#=GS A0A3B5PT34_XIPMA/13-55      AC A0A3B5PT34.1
#=GS A0A671KWP2_9TELE/19-61      AC A0A671KWP2.1
#=GS A0A6P8UVS4_GYMAC/19-61      AC A0A6P8UVS4.1
#=GS A0A803KAK8_XENTR/385-428    AC A0A803KAK8.1
#=GS A0A3Q7QX43_CALUR/29-69      AC A0A3Q7QX43.1
#=GS A0A4W3JAZ6_CALMI/14-53      AC A0A4W3JAZ6.1
#=GS A0A4W4G5K3_ELEEL/4-46       AC A0A4W4G5K3.1
#=GS A0A1L8FD79_XENLA/201-245    AC A0A1L8FD79.1
#=GS A9C3N7_DANRE/135-175        AC A9C3N7.1
#=GS A0A672QS87_SINGR/42-84      AC A0A672QS87.1
#=GS A0A671RF38_9TELE/17-60      AC A0A671RF38.1
#=GS A0A2Y9T977_PHYMC/15-55      AC A0A2Y9T977.1
#=GS A0A4W3JN01_CALMI/29-68      AC A0A4W3JN01.1
#=GS A0A6J2Q5M1_COTGO/15-57      AC A0A6J2Q5M1.1
#=GS A0A1S3R596_SALSA/15-57      AC A0A1S3R596.1
#=GS I7FTT9_PIG/29-69            AC I7FTT9.1
#=GS A0A2K6FX92_PROCO/34-73      AC A0A2K6FX92.1
#=GS A0A5A9ND13_9TELE/12-54      AC A0A5A9ND13.1
#=GS A0A674A1T1_SALTR/72-114     AC A0A674A1T1.1
#=GS A0A1S3SEH1_SALSA/41-80      AC A0A1S3SEH1.1
#=GS A0A6J0V2G2_9SAUR/257-298    AC A0A6J0V2G2.1
#=GS A0A6P7XYK0_9AMPH/16-56      AC A0A6P7XYK0.1
#=GS A0A6J8B8Q1_MYTCO/15-62      AC A0A6J8B8Q1.1
#=GS A0A6I9I128_VICPA/57-100     AC A0A6I9I128.1
#=GS A0A3Q2H8Y9_HORSE/15-55      AC A0A3Q2H8Y9.1
#=GS A0A671WP19_SPAAU/15-57      AC A0A671WP19.1
#=GS F6WHL3_HORSE/16-62          AC F6WHL3.1
#=GS A0A6A5FBU0_PERFL/55-94      AC A0A6A5FBU0.1
#=GS A0A340XC10_LIPVE/16-56      AC A0A340XC10.1
#=GS A0A6I9YR91_9SAUR/16-56      AC A0A6I9YR91.1
#=GS A0A4W3IV49_CALMI/13-52      AC A0A4W3IV49.1
#=GS A0A6P7J7E3_9TELE/16-57      AC A0A6P7J7E3.1
#=GS A0A6P7H8Q3_DIAVI/82-121     AC A0A6P7H8Q3.1
#=GS A0A6P7NT71_BETSP/16-57      AC A0A6P7NT71.1
#=GS A0A060WGG9_ONCMY/37-79      AC A0A060WGG9.1
#=GS A0A3B1K546_ASTMX/15-57      AC A0A3B1K546.1
#=GS A0A671GC62_RHIFE/29-80      AC A0A671GC62.1
#=GS A0A6J2VQA8_CHACN/596-638    AC A0A6J2VQA8.1
#=GS A0A4W3JJ46_CALMI/132-171    AC A0A4W3JJ46.1
#=GS A0A6J2US83_CHACN/15-57      AC A0A6J2US83.1
#=GS A0A3Q7XAJ2_URSAR/20-57      AC A0A3Q7XAJ2.1
#=GS G1TTC1_RABIT/11-52          AC G1TTC1.2
#=GS A0A2K5P029_CERAT/29-69      AC A0A2K5P029.1
#=GS A0A671TBL4_9TELE/14-55      AC A0A671TBL4.1
#=GS A0A6J2LFJ2_9CHIR/16-56      AC A0A6J2LFJ2.1
#=GS A0A6P7XTA7_9AMPH/16-56      AC A0A6P7XTA7.1
#=GS A0A6P8UVK5_GYMAC/26-65      AC A0A6P8UVK5.1
#=GS A0A667WZ97_9TELE/11-51      AC A0A667WZ97.1
#=GS A0A091RQ54_9GRUI/8-48       AC A0A091RQ54.1
#=GS A0A3B1KCS2_ASTMX/14-56      AC A0A3B1KCS2.1
#=GS A0A674IRB2_TERCA/17-59      AC A0A674IRB2.1
#=GS A0A3Q3FZD5_9LABR/15-57      AC A0A3Q3FZD5.1
#=GS A0A671WPJ5_SPAAU/15-57      AC A0A671WPJ5.1
#=GS A0A7E6CP41_9CHIR/11-54      AC A0A7E6CP41.1
#=GS A0A3P9DD26_9CICH/14-56      AC A0A3P9DD26.1
#=GS A0A2K5F2K8_AOTNA/16-56      AC A0A2K5F2K8.1
#=GS A0A6P8FES1_CLUHA/14-56      AC A0A6P8FES1.1
#=GS A0A673K7J6_9TELE/15-57      AC A0A673K7J6.1
#=GS G1PZ52_MYOLU/23-63          AC G1PZ52.1
#=GS A0A6P7WQ58_9AMPH/16-56      AC A0A6P7WQ58.1
#=GS A0A3Q7N392_CALUR/14-56      AC A0A3Q7N392.1
#=GS A0A6J2R5K3_COTGO/17-59      AC A0A6J2R5K3.1
#=GS H2LG90_ORYLA/15-54          AC H2LG90.2
#=GS A0A4W5R6V9_9TELE/10-52      AC A0A4W5R6V9.1
#=GS A0A671VKY0_SPAAU/15-57      AC A0A671VKY0.1
#=GS A0A6J0X3I5_ODOVR/55-95      AC A0A6J0X3I5.1
#=GS A0A401RSS6_CHIPU/12-54      AC A0A401RSS6.1
#=GS TRI69_HUMAN/41-81           AC Q86WT6.2
#=GS TRI69_HUMAN/41-81           DR PDB; 6YXE B; 41-81;
#=GS TRI69_HUMAN/41-81           DR PDB; 6YXE A; 41-81;
#=GS A0A6P5LST9_PHACI/34-77      AC A0A6P5LST9.1
#=GS A0A0P7UVX7_SCLFO/15-57      AC A0A0P7UVX7.1
#=GS A0A3P9DDN4_9CICH/15-57      AC A0A3P9DDN4.1
#=GS A0A7F8RP85_LEPWE/16-65      AC A0A7F8RP85.1
#=GS A0A673HCL1_9TELE/53-95      AC A0A673HCL1.1
#=GS A0A3Q3EH46_9LABR/11-51      AC A0A3Q3EH46.1
#=GS A0A087XCT4_POEFO/27-66      AC A0A087XCT4.2
#=GS A0A671VRY4_SPAAU/15-57      AC A0A671VRY4.1
#=GS A0A3P8U497_AMPPE/15-57      AC A0A3P8U497.1
#=GS A0A3Q3LE29_9LABR/15-54      AC A0A3Q3LE29.1
#=GS H2LPE5_ORYLA/9-36           AC H2LPE5.2
#=GS A0A3P9DC02_9CICH/9-51       AC A0A3P9DC02.1
#=GS A0A673HHK2_9TELE/15-57      AC A0A673HHK2.1
#=GS A0A3Q3MNS0_9LABR/48-91      AC A0A3Q3MNS0.1
#=GS A0A671QPR9_9TELE/15-54      AC A0A671QPR9.1
#=GS A0A671VRT0_SPAAU/58-100     AC A0A671VRT0.1
#=GS F7INH2_CALJA/16-60          AC F7INH2.2
#=GS A0A6J8D6E7_MYTCO/20-61      AC A0A6J8D6E7.1
#=GS A0A3Q3MMJ7_9TELE/15-57      AC A0A3Q3MMJ7.2
#=GS A0A3Q4H5V7_NEOBR/22-64      AC A0A3Q4H5V7.1
#=GS A0A452IIX4_9SAUR/15-55      AC A0A452IIX4.1
#=GS A0A6P6DE47_OCTDE/15-58      AC A0A6P6DE47.1
#=GS A0A060Y1N4_ONCMY/16-58      AC A0A060Y1N4.1
#=GS G3S4J1_GORGO/11-53          AC G3S4J1.2
#=GS A0A3Q1HBM1_9TELE/9-51       AC A0A3Q1HBM1.1
#=GS R4GDG9_ANOCA/16-57          AC R4GDG9.1
#=GS A0A6J0DJ94_PERMB/15-58      AC A0A6J0DJ94.1
#=GS A0A091DC76_FUKDA/205-245    AC A0A091DC76.1
#=GS A0A4W4G1I6_ELEEL/16-58      AC A0A4W4G1I6.1
#=GS A0A672I8B1_SALFA/98-140     AC A0A672I8B1.1
#=GS A0A670YWY2_PSETE/18-62      AC A0A670YWY2.1
#=GS A0A670JUH3_PODMU/36-76      AC A0A670JUH3.1
#=GS E1BM69_BOVIN/15-59          AC E1BM69.3
#=GS W2Z3I4_PHYPR/39-93          AC W2Z3I4.1
#=GS A0A3Q3N9E3_9LABR/15-55      AC A0A3Q3N9E3.1
#=GS A0A4W3GVB5_CALMI/16-55      AC A0A4W3GVB5.1
#=GS A0A672NK22_SINGR/13-55      AC A0A672NK22.1
#=GS A0A6J0V0S2_9SAUR/17-57      AC A0A6J0V0S2.1
#=GS A0A6I9JCY5_CHRAS/16-56      AC A0A6I9JCY5.1
#=GS A0A0N4STV9_DANRE/15-57      AC A0A0N4STV9.1
#=GS A0A4W5PT68_9TELE/15-57      AC A0A4W5PT68.1
#=GS A0A2K6QA64_RHIRO/16-56      AC A0A2K6QA64.1
#=GS A0A6Q2Y3W3_ESOLU/10-52      AC A0A6Q2Y3W3.1
#=GS A0A3Q3MH82_9TELE/16-57      AC A0A3Q3MH82.1
#=GS F6ZEA2_CALJA/9-57           AC F6ZEA2.2
#=GS A0A2K5DBC9_AOTNA/15-55      AC A0A2K5DBC9.1
#=GS A0A3B1JNY9_ASTMX/15-57      AC A0A3B1JNY9.1
#=GS A0A6J2PBB8_COTGO/15-57      AC A0A6J2PBB8.1
#=GS A0A672L5G9_SINGR/13-55      AC A0A672L5G9.1
#=GS A0A6G1QW38_9TELE/12-54      AC A0A6G1QW38.1
#=GS A0A3B3I9G8_ORYLA/24-66      AC A0A3B3I9G8.1
#=GS A0A671VL37_SPAAU/15-57      AC A0A671VL37.1
#=GS A0A1L8END8_XENLA/14-55      AC A0A1L8END8.1
#=GS A0A672SBR6_SINGR/14-56      AC A0A672SBR6.1
#=GS A0A401P5S7_SCYTO/13-53      AC A0A401P5S7.1
#=GS A0A0G4EQZ3_VITBC/48-81      AC A0A0G4EQZ3.1
#=GS A0A674EMS2_SALTR/15-56      AC A0A674EMS2.1
#=GS A0A0G2JYE1_RAT/15-58        AC A0A0G2JYE1.1
#=GS A0A4W3K5I0_CALMI/11-50      AC A0A4W3K5I0.1
#=GS A0A671RRE0_9TELE/15-57      AC A0A671RRE0.1
#=GS A0A6P7MQU8_BETSP/45-87      AC A0A6P7MQU8.1
#=GS A0A3Q7WL22_URSAR/16-56      AC A0A3Q7WL22.1
#=GS A0A671LGD1_9TELE/8-48       AC A0A671LGD1.1
#=GS TRI72_RAT/14-56             AC A0JPQ4.1
#=GS A0A673JPZ4_9TELE/13-55      AC A0A673JPZ4.1
#=GS A0A2U3V960_TURTR/16-56      AC A0A2U3V960.1
#=GS A0A6P7ICN0_9TELE/15-57      AC A0A6P7ICN0.1
#=GS A0A151N2K2_ALLMI/13-53      AC A0A151N2K2.1
#=GS A0A671TK14_SPAAU/60-102     AC A0A671TK14.1
#=GS A0A2I3N8M9_PAPAN/34-73      AC A0A2I3N8M9.1
#=GS A0A3Q3L463_9LABR/15-57      AC A0A3Q3L463.1
#=GS A0A6P7P1W5_BETSP/13-55      AC A0A6P7P1W5.1
#=GS A0A6J2PIN2_COTGO/15-57      AC A0A6J2PIN2.1
#=GS A0A6P8UTH8_GYMAC/19-61      AC A0A6P8UTH8.1
#=GS A0A4W3GDR3_CALMI/16-58      AC A0A4W3GDR3.1
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#=GS A0A3Q7RG51_VULVU/43-83      AC A0A3Q7RG51.1
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#=GS A0A7N4NWM6_SARHA/190-230    AC A0A7N4NWM6.1
#=GS A0A452R2D2_URSAM/22-62      AC A0A452R2D2.1
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#=GS H2ZW87_LATCH/12-51          AC H2ZW87.1
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#=GS E9PFM0_HUMAN/15-59          AC E9PFM0.1
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#=GS A0A6I8SK39_XENTR/469-512    AC A0A6I8SK39.2
#=GS A0A0D2Q9B4_HYPSF/4-47       AC A0A0D2Q9B4.1
#=GS A0A5N5JDL4_PANHP/15-57      AC A0A5N5JDL4.1
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#=GS A0A3Q2D2A9_CYPVA/10-52      AC A0A3Q2D2A9.1
#=GS A0A7N6ACS6_ANATE/27-71      AC A0A7N6ACS6.1
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#=GS A0A6P8GME6_CLUHA/510-552    AC A0A6P8GME6.1
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#=GS A0A2U4BM35_TURTR/9-57       AC A0A2U4BM35.1
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