GenomeNet

Database: Pfam
Entry: zf-RAG1
LinkDB: zf-RAG1
Original site: zf-RAG1 
#=GF ID   zf-RAG1
#=GF AC   PF10426.12
#=GF DE   Recombination-activating protein 1 zinc-finger domain
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Gene3D, pdb_1rmd
#=GF GA   22.00 22.00;
#=GF TC   22.00 22.80;
#=GF NC   21.80 20.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0361
#=GF RN   [1]
#=GF RM   9228952
#=GF RT   Crystal structure of the RAG1 dimerization domain reveals
#=GF RT   multiple zinc-binding motifs including a novel zinc binuclear
#=GF RT   cluster. 
#=GF RA   Bellon SF, Rodgers KK, Schatz DG, Coleman JE, Steitz TA; 
#=GF RL   Nat Struct Biol. 1997;4:586-591.
#=GF DR   INTERPRO; IPR019485;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This is a C2-H2 zinc-finger domain closely resembling the
#=GF CC   classical TFIIIA-type zinc-finger, CX3FX5LX2-3H, despite having
#=GF CC   a valine and a tyrosine at the core instead of a phenylalanine
#=GF CC   and a leucine, hence CX3VX1LX2YX2H.  The structure,
#=GF CC   nevertheless, contains the characteristic two-stranded
#=GF CC   beta-sheet and alpha-helix of a classical zinc-finger. The
#=GF CC   domain binds one zinc and, in complex with the zinc-RING-finger
#=GF CC   domain, helps to stabilise the whole of the dimerisation region
#=GF CC   of recombination activating protein 1 (RAG1) [1]. The function
#=GF CC   of the whole is to bind double-stranded DNA.
#=GF SQ   164
#=GS A0A384A1T6_BALAS/354-383  AC A0A384A1T6.1
#=GS A0A6J1TQ04_9SAUR/355-384  AC A0A6J1TQ04.1
#=GS A0A670HMQ9_PODMU/356-385  AC A0A670HMQ9.1
#=GS A0A091QQR1_HALAL/346-375  AC A0A091QQR1.1
#=GS A0A2I0MPH0_COLLI/344-373  AC A0A2I0MPH0.1
#=GS G1NTJ5_MYOLU/354-383      AC G1NTJ5.1
#=GS M3Z8B8_MUSPF/354-383      AC M3Z8B8.1
#=GS A0A5N4DL36_CAMDR/354-383  AC A0A5N4DL36.1
#=GS A0A1L8GIM4_XENLA/355-384  AC A0A1L8GIM4.1
#=GS A0A1S3FEP4_DIPOR/354-383  AC A0A1S3FEP4.1
#=GS A0A2K5UF18_MACFA/354-383  AC A0A2K5UF18.2
#=GS RAG1_RABIT/353-382        AC P34088.1
#=GS E2RDF6_CANLF/382-411      AC E2RDF6.2
#=GS A0A4U1FRI8_MONMO/391-420  AC A0A4U1FRI8.1
#=GS A0A2R9CSL6_PANPA/354-383  AC A0A2R9CSL6.1
#=GS RAG1_CHICK/350-379        AC P24271.1
#=GS A0A2U3V9Q8_TURTR/354-383  AC A0A2U3V9Q8.2
#=GS A0A2K5HAC0_COLAP/354-383  AC A0A2K5HAC0.1
#=GS A0A2R8MLP7_CALJA/354-383  AC A0A2R8MLP7.1
#=GS A0A2K6S7R8_SAIBB/354-383  AC A0A2K6S7R8.1
#=GS A0A2U3XZ32_LEPWE/354-383  AC A0A2U3XZ32.1
#=GS A0A226MQZ7_CALSU/389-418  AC A0A226MQZ7.1
#=GS A0A674IYI5_TERCA/356-385  AC A0A674IYI5.1
#=GS A0A803JEW6_XENTR/356-385  AC A0A803JEW6.1
#=GS L8YCQ6_TUPCH/153-182      AC L8YCQ6.1
#=GS A0A6P5CYY2_BOSIN/354-383  AC A0A6P5CYY2.1
#=GS A0A6J3I8C6_SAPAP/354-383  AC A0A6J3I8C6.1
#=GS A0A1D5PU72_CHICK/350-379  AC A0A1D5PU72.1
#=GS A0A3Q7SXG0_VULVU/354-383  AC A0A3Q7SXG0.1
#=GS A0A452S6I0_URSAM/354-383  AC A0A452S6I0.1
#=GS A0A2Y9P7L1_DELLE/354-383  AC A0A2Y9P7L1.1
#=GS G1MM47_AILME/379-408      AC G1MM47.1
#=GS RAG1_MOUSE/351-380        AC P15919.2
#=GS RAG1_MOUSE/351-380        DR PDB; 1RMD A; 87-116;
#=GS A0A2P4T241_BAMTH/344-373  AC A0A2P4T241.1
#=GS A0A093EE50_TAUER/346-375  AC A0A093EE50.1
#=GS A0A1S2ZN11_ERIEU/353-382  AC A0A1S2ZN11.1
#=GS A0A091FX46_9AVES/346-375  AC A0A091FX46.1
#=GS A0A0A0A5Z8_CHAVO/346-375  AC A0A0A0A5Z8.1
#=GS A0A6P5IEP7_PHACI/357-386  AC A0A6P5IEP7.1
#=GS G1NRN5_MELGA/351-380      AC G1NRN5.1
#=GS H0ZIP6_TAEGU/350-379      AC H0ZIP6.2
#=GS A0A6I9Z653_9SAUR/355-384  AC A0A6I9Z653.1
#=GS K7F194_PELSI/348-377      AC K7F194.1
#=GS A0A3Q7X0C1_URSAR/354-383  AC A0A3Q7X0C1.1
#=GS RAG1_PIG/354-383          AC Q867B5.1
#=GS A0A340Y5B9_LIPVE/354-383  AC A0A340Y5B9.1
#=GS A0A5F8A8N1_MACMU/392-421  AC A0A5F8A8N1.1
#=GS A0A0P7YW53_SCLFO/480-509  AC A0A0P7YW53.1
#=GS F1MG60_BOVIN/354-383      AC F1MG60.2
#=GS I3L7X1_PIG/354-383        AC I3L7X1.1
#=GS A0A6J2HL81_9PASS/346-375  AC A0A6J2HL81.1
#=GS A0A2I0TUN8_LIMLA/485-514  AC A0A2I0TUN8.1
#=GS A0A6I9ZTG4_ACIJB/354-383  AC A0A6I9ZTG4.1
#=GS A0A6I9LSX2_PERMB/356-385  AC A0A6I9LSX2.1
#=GS RAG1_HUMAN/354-383        AC P15918.2
#=GS A0A093QUR9_PHACA/347-376  AC A0A093QUR9.1
#=GS U3KIY3_FICAL/350-379      AC U3KIY3.1
#=GS A0A6P3GUS8_BISBI/354-383  AC A0A6P3GUS8.1
#=GS A0A091GRE2_BUCRH/342-371  AC A0A091GRE2.1
#=GS A0A2Y9GME8_NEOSC/354-383  AC A0A2Y9GME8.1
#=GS A0A226PQ49_COLVI/351-380  AC A0A226PQ49.1
#=GS A0A091F4N0_CORBR/365-394  AC A0A091F4N0.1
#=GS A0A5G2QEE1_PIG/360-389    AC A0A5G2QEE1.1
#=GS A0A093BP54_CHAPE/340-369  AC A0A093BP54.1
#=GS A0A673UJL3_SURSU/354-383  AC A0A673UJL3.1
#=GS A0A087R843_APTFO/346-375  AC A0A087R843.1
#=GS A0A3S2PF27_ORYJA/401-428  AC A0A3S2PF27.1
#=GS A0A6I9HF52_GEOFO/350-379  AC A0A6I9HF52.1
#=GS A0A6P7XIL7_9AMPH/348-377  AC A0A6P7XIL7.1
#=GS A0A2K5LZS8_CERAT/376-405  AC A0A2K5LZS8.1
#=GS A0A094NA83_ANTCR/346-375  AC A0A094NA83.1
#=GS A0A6J3CYE2_AYTFU/350-379  AC A0A6J3CYE2.1
#=GS A0A218UYR9_9PASE/362-391  AC A0A218UYR9.1
#=GS H2M917_ORYLA/323-350      AC H2M917.2
#=GS F6WSB4_HORSE/353-382      AC F6WSB4.1
#=GS A0A402EZ55_9SAUR/366-395  AC A0A402EZ55.1
#=GS A0A093PU14_9PASS/346-375  AC A0A093PU14.1
#=GS A0A6J0V9G2_9SAUR/356-385  AC A0A6J0V9G2.1
#=GS R0LZS8_ANAPL/350-379      AC R0LZS8.1
#=GS L8IV89_9CETA/354-383      AC L8IV89.1
#=GS A0A6J2M5H8_9CHIR/355-384  AC A0A6J2M5H8.1
#=GS H0W9U1_CAVPO/354-383      AC H0W9U1.1
#=GS Q28463_MONDO/358-387      AC Q28463.1
#=GS U3IW73_ANAPP/350-379      AC U3IW73.1
#=GS A0A663MAU8_ATHCN/346-375  AC A0A663MAU8.1
#=GS A0A6I9JTP4_CHRAS/355-384  AC A0A6I9JTP4.1
#=GS A0A401S7R4_CHIPU/360-389  AC A0A401S7R4.1
#=GS A0A452EFW4_CAPHI/354-383  AC A0A452EFW4.1
#=GS A0A6J0YG40_ODOVR/354-383  AC A0A6J0YG40.1
#=GS A0A2I3RIF0_PANTR/354-383  AC A0A2I3RIF0.1
#=GS A0A6P3PWM9_PTEVA/354-383  AC A0A6P3PWM9.1
#=GS A0A099Z620_TINGU/351-380  AC A0A099Z620.1
#=GS A0A2K6NRR9_RHIRO/354-383  AC A0A2K6NRR9.1
#=GS G5B131_HETGA/355-384      AC G5B131.1
#=GS A0A091NYQ5_9PASS/346-375  AC A0A091NYQ5.1
#=GS T0NNM4_CAMFR/354-383      AC T0NNM4.1
#=GS A0A2U3WKH9_ODORO/354-383  AC A0A2U3WKH9.1
#=GS H2M914_ORYLA/394-421      AC H2M914.2
#=GS A0A7N4PGC1_SARHA/358-387  AC A0A7N4PGC1.1
#=GS A0A096N450_PAPAN/354-383  AC A0A096N450.1
#=GS A0A0D9QZL1_CHLSB/354-383  AC A0A0D9QZL1.1
#=GS A0A091I8R8_CALAN/340-369  AC A0A091I8R8.1
#=GS A0A485MYH6_LYNPA/354-383  AC A0A485MYH6.1
#=GS A0A6I9INT1_VICPA/354-383  AC A0A6I9INT1.1
#=GS A0A2K6K332_RHIBE/354-383  AC A0A2K6K332.1
#=GS A0A2Y9EQ27_PHYMC/354-383  AC A0A2Y9EQ27.1
#=GS W5PL78_SHEEP/354-383      AC W5PL78.1
#=GS A0A3M0JHE5_HIRRU/369-398  AC A0A3M0JHE5.1
#=GS H3A5N4_LATCH/353-382      AC H3A5N4.1
#=GS A0A091CM61_FUKDA/126-155  AC A0A091CM61.1
#=GS A0A384BR25_URSMA/354-383  AC A0A384BR25.1
#=GS A0A6P8PPR8_GEOSA/359-388  AC A0A6P8PPR8.1
#=GS A0A5N3XBK2_MUNRE/354-383  AC A0A5N3XBK2.1
#=GS G3V6K9_RAT/351-380        AC G3V6K9.1
#=GS A0A6I8NR56_ORNAN/374-403  AC A0A6I8NR56.1
#=GS A0A663E4Q1_AQUCH/346-375  AC A0A663E4Q1.1
#=GS A0A669PCF2_PHACC/402-431  AC A0A669PCF2.1
#=GS A0A1U7SPR9_CARSF/354-383  AC A0A1U7SPR9.1
#=GS A0A1U7THL9_CARSF/354-383  AC A0A1U7THL9.1
#=GS A0A6G1AHL8_CROCR/354-383  AC A0A6G1AHL8.1
#=GS A0A093P3X5_PYGAD/346-375  AC A0A093P3X5.1
#=GS A0A671DZM3_RHIFE/354-383  AC A0A671DZM3.1
#=GS A0A2K5C5Z1_AOTNA/354-383  AC A0A2K5C5Z1.1
#=GS A0A091W6F9_OPIHO/346-375  AC A0A091W6F9.1
#=GS A0A2K5PMU9_CEBIM/354-383  AC A0A2K5PMU9.1
#=GS A0A643ATJ7_BALPH/354-383  AC A0A643ATJ7.1
#=GS A0A093I8M0_STRCA/351-380  AC A0A093I8M0.1
#=GS G3UKA0_LOXAF/354-383      AC G3UKA0.1
#=GS A0A091JRA9_EGRGA/346-375  AC A0A091JRA9.1
#=GS A0A6P9C402_PANGU/355-384  AC A0A6P9C402.1
#=GS A0A1V4KEB9_PATFA/344-373  AC A0A1V4KEB9.1
#=GS A0A1U8C9P5_MESAU/352-381  AC A0A1U8C9P5.1
#=GS I3MY25_ICTTR/354-383      AC I3MY25.1
#=GS G1S8G7_NOMLE/354-383      AC G1S8G7.1
#=GS A0A091Q6E1_LEPDC/346-375  AC A0A091Q6E1.1
#=GS A0A091RIN4_9GRUI/346-375  AC A0A091RIN4.1
#=GS A0A401P966_SCYTO/352-381  AC A0A401P966.1
#=GS L5KYG5_PTEAL/397-426      AC L5KYG5.1
#=GS G1KDK1_ANOCA/356-384      AC G1KDK1.2
#=GS A0A2Y9JV89_ENHLU/354-383  AC A0A2Y9JV89.1
#=GS A0A212DHZ8_CEREH/161-190  AC A0A212DHZ8.1
#=GS A0A1L8GE69_XENLA/355-384  AC A0A1L8GE69.1
#=GS A0A2I3T8S9_PANTR/354-383  AC A0A2I3T8S9.1
#=GS A0A1A6HQ99_NEOLE/400-429  AC A0A1A6HQ99.1
#=GS G1TU62_RABIT/439-468      AC G1TU62.2
#=GS A0A151MBE1_ALLMI/345-374  AC A0A151MBE1.1
#=GS A0A6P8PIW8_GEOSA/394-423  AC A0A6P8PIW8.1
#=GS A0A3Q7PJN5_CALUR/354-383  AC A0A3Q7PJN5.1
#=GS A0A6P6ICI4_PUMCO/354-383  AC A0A6P6ICI4.1
#=GS W5LZ93_LEPOC/356-385      AC W5LZ93.1
#=GS A0A670YKZ3_PSETE/351-380  AC A0A670YKZ3.1
#=GS A0A6P3EZE1_OCTDE/354-383  AC A0A6P3EZE1.1
#=GS A0A2K6ARB2_MACNE/354-383  AC A0A2K6ARB2.1
#=GS A0A452H4I7_9SAUR/358-387  AC A0A452H4I7.1
#=GS A0A4X2L299_VOMUR/358-387  AC A0A4X2L299.1
#=GS A0A2K5XFH0_MANLE/354-383  AC A0A2K5XFH0.1
#=GS A0A341C1J8_NEOAA/354-383  AC A0A341C1J8.1
#=GS A0A672UXW5_STRHB/342-371  AC A0A672UXW5.1
#=GS A0A093IWW8_DRYPU/346-375  AC A0A093IWW8.1
#=GS A0A4W2E8Q3_BOBOX/354-383  AC A0A4W2E8Q3.1
#=GS A0A2I2ZGP8_GORGO/354-383  AC A0A2I2ZGP8.1
#=GS A0A2Y9D8H7_TRIMA/354-383  AC A0A2Y9D8H7.1
#=GS A0A0Q3LSI9_AMAAE/332-361  AC A0A0Q3LSI9.1
#=GS A0A091UWK0_NIPNI/346-375  AC A0A091UWK0.1
A0A384A1T6_BALAS/354-383             ....LMVKCPAKECNEEVSLEKYNHHVSSHKESK...
A0A6J1TQ04_9SAUR/355-384             ....LVLRCPIKDCHEEVFLEKYCQHRSNHK---gae
A0A670HMQ9_PODMU/356-385             ....LAVRCPVKGCHEEVLLGKYCHHLSIHKEV-e..
A0A091QQR1_HALAL/346-375             ....LGIRCPVKECDEEILHGKYSQHLSSHKEMK...
A0A2I0MPH0_COLLI/344-373             ....LGIRCPVKECDEEILHGKYSQHLSSHKEMK...
G1NTJ5_MYOLU/354-383                 ....LMVKCPAQECNEEVSLEKYNHHVASHKDSK...
M3Z8B8_MUSPF/354-383                 ....LMVKCPAKECNEEISLEKYNHHVSSHKESK...
A0A5N4DL36_CAMDR/354-383             ....LTVKCPAQECNEEVSLEKYNHHVSSHKESK...
A0A1L8GIM4_XENLA/355-384             ....LLLKCTVSGCDEEIPLGKYSHHISKHKETK...
A0A1S3FEP4_DIPOR/354-383             ....LLVKCPAKECNEEVSLEKYNHHVSSHKESK...
A0A2K5UF18_MACFA/354-383             ....LMVKCPAKECNQEVSLEKYNHHISSHKESK...
RAG1_RABIT/353-382                   ....LIVKCSAPECNEEVSLEKYNHHVSSHKE--sr.
E2RDF6_CANLF/382-411                 ....LMVRCPAKGCDEEVSLERYNQHVAGHKD--sd.
A0A4U1FRI8_MONMO/391-420             ....LMVKCPAKECNEEVSLEKYNHHVSSHKESK...
A0A2R9CSL6_PANPA/354-383             ....LMVKCPAKECNEEVSLEKYNHHISSHKESK...
RAG1_CHICK/350-379                   ....LSIRCPVPECDEEILHGKYGQHFSNHKEMK...
A0A2U3V9Q8_TURTR/354-383             ....LMVKCPAKECNEEVSLEKYNHHVSSHKESK...
A0A2K5HAC0_COLAP/354-383             ....LMVKCPAKECNQEISLEKYNHHVSSHKESK...
A0A2R8MLP7_CALJA/354-383             ....LMVKCPAQECNEVVSLEKYNHHISSHKESK...
A0A2K6S7R8_SAIBB/354-383             ....LMVRCPAKECNEVVSLEKYNHHISSHKESK...
A0A2U3XZ32_LEPWE/354-383             ....LMVKCPAKECNEEVSLEKYNHHVSSHKESK...
A0A226MQZ7_CALSU/389-418             ....LSIRCPVPECDEEILHGKYSQHFSNHKEMK...
A0A674IYI5_TERCA/356-385             ....LAVRCPVKECDEEVLLGKYCHHLSSHKEVK...
A0A803JEW6_XENTR/356-385             ....LLLKCTVSGCDEEIPLGKYSHHISKHKETK...
L8YCQ6_TUPCH/153-182                 ....LVVRCPAKECSEEVSLEKYNHHVSSHKESK...
A0A6P5CYY2_BOSIN/354-383             ....LMVKCPAEECDEEVSLEKYNHHVSSHKESK...
A0A6J3I8C6_SAPAP/354-383             ....LMVKCPAKECNEVVSLEKYNHHISSHKESK...
A0A1D5PU72_CHICK/350-379             ....LSIRCPVPECDEEILHGKYGQHFSNHKEMK...
A0A3Q7SXG0_VULVU/354-383             ....LMVKCPAKGCDEEVSLERYNQHVAGHKD--sd.
A0A452S6I0_URSAM/354-383             ....LMVKCPAKECNEEVSLEKYNHHVSSHKESK...
A0A2Y9P7L1_DELLE/354-383             ....LMVKCPAKECNEEVSLEKYNHHVSSHKESK...
G1MM47_AILME/379-408                 ....LMVKCPAKECNEEVSLEKYNRHVSSHKESK...
RAG1_MOUSE/351-380                   ....LMVKCPAQDCNEEVSLEKYNHHVSSHKESK...
#=GR RAG1_MOUSE/351-380        SS    ....-EEE--STT---EEEHHHHHHHHHTS----...
A0A2P4T241_BAMTH/344-373             ....LSIRCPVPECDEEILHGKYGQHFSNHKEMK...
A0A093EE50_TAUER/346-375             ....LSIRCPVKECDEEVLYGKYGQHLSNHKEMK...
A0A1S2ZN11_ERIEU/353-382             ....LLVKCPAKGCNEEVSLEKYNHHVSSHKESK...
A0A091FX46_9AVES/346-375             ....LAVRCPVKECDEEILHGKYGQHLSSHKETK...
A0A0A0A5Z8_CHAVO/346-375             ....LGIRCPVKECDEEILHGKYGQHLSSHKEMK...
A0A6P5IEP7_PHACI/357-386             ....LVVRCPVKDCDKEVSLEKYNQHISSHKEPK...
G1NRN5_MELGA/351-380                 ....LSIRCPVPECDEEILYGKYGQHFSNHKEMK...
H0ZIP6_TAEGU/350-379                 ....LNIRCPVKECDEEISHGKYGQHLSGHKEMK...
A0A6I9Z653_9SAUR/355-384             ....LVLRCPVKGCHEEVFLEKYCQHRSNHK---gae
K7F194_PELSI/348-377                 ....LAVRCPVKECDEEVLLGKYCHHLSSHKELK...
A0A3Q7X0C1_URSAR/354-383             ....LMVKCPAKECNEEVSLEKYNHHVSSHKESK...
RAG1_PIG/354-383                     ....LMVKCPAKECNEEISLEKYNHHISSHKESK...
A0A340Y5B9_LIPVE/354-383             ....LMVKCPAKECNEEVSLEKYNHHVSSHKDSK...
A0A5F8A8N1_MACMU/392-421             ....LMVKCPAKECNQEVSLEKYNHHISSHKESK...
A0A0P7YW53_SCLFO/480-509             ....LLLRCPREDCREAVRLESFGSHCRGHQE--ad.
F1MG60_BOVIN/354-383                 ....LMVKCPAEECDEEVSLEKYNHHVSSHKESK...
I3L7X1_PIG/354-383                   ....LMVKCPAKECNEEISLEKYNHHISSHKESK...
A0A6J2HL81_9PASS/346-375             ....LGIRCPVKECDEEILHGKYGQHLSNHKEMK...
A0A2I0TUN8_LIMLA/485-514             ....LGIRCPVKECDEEILHGKYGQHLSSHKEMK...
A0A6I9ZTG4_ACIJB/354-383             ....LMVRCPAKECNEEVSLEKYNHHVSSHKESK...
A0A6I9LSX2_PERMB/356-385             ....LMVKCPAQECNEEVSLEKYNHHVSSHKESK...
RAG1_HUMAN/354-383                   ....LMVKCPAKECNEEVSLEKYNHHISSHKESK...
A0A093QUR9_PHACA/347-376             ....LGIRCPIKECDEEILHGKYGQHLSSHKEMK...
U3KIY3_FICAL/350-379                 ....LGIRCPVKECDEEIMHGKYGQHLSGHKEMK...
A0A6P3GUS8_BISBI/354-383             ....LMVKCPAEECDEEVSLEKYNHHVSSHKESK...
A0A091GRE2_BUCRH/342-371             ....LGIRCPVKECDEEIFHRKYGQHLSSHKEMK...
A0A2Y9GME8_NEOSC/354-383             ....LMVKCPAKECNEEVSLEKYNHHVSSHKESK...
A0A226PQ49_COLVI/351-380             ....LSIRCPVPECDEEILHGKYSQHFSNHKEMK...
A0A091F4N0_CORBR/365-394             ....LSIRCPVKECDEEILHGKYGQHLSSHKEMK...
A0A5G2QEE1_PIG/360-389               ....LMVKCPAKECNEEISLEKYNHHISSHKESK...
A0A093BP54_CHAPE/340-369             ....LGIRCPIKKCDEEILHGKYGQHLSSHKEMK...
A0A673UJL3_SURSU/354-383             ....LMVRCPAKECNEEISLEKYNRHVSSHKESK...
A0A087R843_APTFO/346-375             ....LGIRCPVKECDEEILHGKYGQHLSSHKEMK...
A0A3S2PF27_ORYJA/401-428             llll----CPSDGCDEEVRLDSIKAHCLSHK---l..
A0A6I9HF52_GEOFO/350-379             ....LNIRCPVKECDEEISHGKYGQHLSGHKEMK...
A0A6P7XIL7_9AMPH/348-377             ....LVLRCTVKQCDEEVSLGKYVNHICAHKETK...
A0A2K5LZS8_CERAT/376-405             ....LMVKCPAKECNQEVSLEKYNHHISSHKESK...
A0A094NA83_ANTCR/346-375             ....LGIRCPVKECDEEILLGKYGQHLSSHKEMK...
A0A6J3CYE2_AYTFU/350-379             ....LSIRCPVKECDEEILHGKYGQHLSSHKEMK...
A0A218UYR9_9PASE/362-391             ....LNIRCPVKECDEEISHGKYGQHLSGHKEMK...
H2M917_ORYLA/323-350                 llll----CPSDGCDEEVRLDSIKAHCLSHK---l..
F6WSB4_HORSE/353-382                 ....LMVKCPAEECNEEVSLEKYNHHVSSHKESK...
A0A402EZ55_9SAUR/366-395             ....LGVKCPVKDCHEEVTLGKYSHHLSSHKEKK...
A0A093PU14_9PASS/346-375             ....LGIRCPVKECDEEILHGKYGQHLSSHKEMK...
A0A6J0V9G2_9SAUR/356-385             ....LILRCPVKDCQEEVVLGKYAHHFSSHKE--ae.
R0LZS8_ANAPL/350-379                 ....LSIRCPVKECDEEILHGKYGQHLSSHKEMK...
L8IV89_9CETA/354-383                 ....LMVKCPAEECDEEVSLEKYNHHVSSHKESK...
A0A6J2M5H8_9CHIR/355-384             ....LMVKCPAKECDEEVSLEKYNHHVSTHKNAK...
H0W9U1_CAVPO/354-383                 ....LMVKCPAKECNEEVSLEKYNQHVLSHKESK...
Q28463_MONDO/358-387                 ....LVVRCPVKDCDKDVSLEKYNQHISSHKEPK...
U3IW73_ANAPP/350-379                 ....LSIRCPVKECDEEILHGKYGQHLSSHKEMK...
A0A663MAU8_ATHCN/346-375             ....LGIRCPVKECDEEILHGKYGQHLSSHKEMK...
A0A6I9JTP4_CHRAS/355-384             ....LMVICPAKECNEEVSLEKYNHHVSSHRESK...
A0A401S7R4_CHIPU/360-389             ....LVLKCPATDCEMEVRLGEYSNHAQNHKET-r..
A0A452EFW4_CAPHI/354-383             ....LMVKCPAEECDEEVTLEKYNHHVSSHKESK...
A0A6J0YG40_ODOVR/354-383             ....LMVKCPAEECDEEVSLEKYNHHVSSHKESK...
A0A2I3RIF0_PANTR/354-383             ....LMVKCPAKECNEEVSLEKYNHHISSHKESK...
A0A6P3PWM9_PTEVA/354-383             ....LMVKCPAQECNEEVSLEKYNHHVSSHKDSK...
A0A099Z620_TINGU/351-380             ....LGIRCPVKECDEEIMLGKYGQHLSSHKLMK...
A0A2K6NRR9_RHIRO/354-383             ....LMVKCPAKECNQEISLEKYNHHVSSHKESK...
G5B131_HETGA/355-384                 ....LMVKCPAKECSEEVSLEKYNQHVSSHKESK...
A0A091NYQ5_9PASS/346-375             ....LSIRCPVKDCDEEIRYGKYSQHLSSHKEMK...
T0NNM4_CAMFR/354-383                 ....LTVKCPAQECNEEVSLEKYNHHVSSHKESK...
A0A2U3WKH9_ODORO/354-383             ....LMVKCPAKECNEEVSLEKYNHHVSSHKESK...
H2M914_ORYLA/394-421                 llll----CPSDGCDEEVRLDSIKAHCLSHK---l..
A0A7N4PGC1_SARHA/358-387             ....LLVKCPVNDCDKEVSFEKYNQHISSHKEPK...
A0A096N450_PAPAN/354-383             ....LKVKCPAKECNQEVSLEKYNHHISSHKESK...
A0A0D9QZL1_CHLSB/354-383             ....LMVKCPAKECNQEVSLEKYNHHVSSHKESK...
A0A091I8R8_CALAN/340-369             ....LRVRCPVKECDEEILHGKYGQHLSNHKEMK...
A0A485MYH6_LYNPA/354-383             ....LMVRCPAKECNEEVSLEKYNHHVSSHKESK...
A0A6I9INT1_VICPA/354-383             ....LTVKCPAQECNEEVSLEKYNHHVSSHKESK...
A0A2K6K332_RHIBE/354-383             ....LMVKCPAKECNQEISLEKYNHHVSSHKESK...
A0A2Y9EQ27_PHYMC/354-383             ....LTVKCPAKECNEEVSLEKYNHHVSSHKESK...
W5PL78_SHEEP/354-383                 ....LMVKCPAEECDEEVTLEKYNHHVSSHKESK...
A0A3M0JHE5_HIRRU/369-398             ....LSIRCPVKECDEEILHGKYGQHLSSHKEMK...
H3A5N4_LATCH/353-382                 ....LMVKCPAKECDEQVRLEEYSSHSQSHKEVK...
A0A091CM61_FUKDA/126-155             ....LMVKCPAKECSEEVSLEKYNQHISSHKE--sr.
A0A384BR25_URSMA/354-383             ....LMVKCPAKECNEEVSLEKYNHHVSSHKESK...
A0A6P8PPR8_GEOSA/359-388             ....LVLRCTVKECGEEVSLGKYANHLSAHTETK...
A0A5N3XBK2_MUNRE/354-383             ....LMVKCPAEECDEEVSLEKYNHHVSSHKESK...
G3V6K9_RAT/351-380                   ....LMVKCPAQECNEEVSLEKYNHHVSSHKESK...
A0A6I8NR56_ORNAN/374-403             ....LVVRCPAEECDEEVSLEKYNHHASSHKETK...
A0A663E4Q1_AQUCH/346-375             ....LGIRCPVKECDEEILHGKYGQHLSSHKEMK...
A0A669PCF2_PHACC/402-431             ....LSIRCPVPECDEEILHGKYGQHFSNHKEMK...
A0A1U7SPR9_CARSF/354-383             ....LIVKCPAKECNEEISLEKYNHHVSSHKDSK...
A0A1U7THL9_CARSF/354-383             ....LIVKCPAKECNEEISLEKYNHHVSSHKDSK...
A0A6G1AHL8_CROCR/354-383             ....LMVRCPAKECNEAISLEKYNHHVSSHKESK...
A0A093P3X5_PYGAD/346-375             ....LGIRCPVKECDEEILHGKYGQHLSSHKEMK...
A0A671DZM3_RHIFE/354-383             ....LMVKCPAQECNEEVSLEKYNHHVSRHKDSK...
A0A2K5C5Z1_AOTNA/354-383             ....LMVKCPAQECNEVVSLEKYNHHISSHKESK...
A0A091W6F9_OPIHO/346-375             ....LGIRCPIKECDEEILYGKYSQHLSSHKEMK...
A0A2K5PMU9_CEBIM/354-383             ....LMVKCPAKECNEVVSLEKYNHHISSHKESK...
A0A643ATJ7_BALPH/354-383             ....LMVKCPAKECNEEVSLEKYNHHVSSHKESK...
A0A093I8M0_STRCA/351-380             ....LGIRCSVKECDEEILLGKYSQHLSSHKEMK...
G3UKA0_LOXAF/354-383                 ....LMVKCPAKECSEEVSLEKYNHHVSSHKESK...
A0A091JRA9_EGRGA/346-375             ....LGIRCPVKECDEEVLHGKYGQHLSSHKEMK...
A0A6P9C402_PANGU/355-384             ....LVLRCPVKGCHEEVFLEKYCQHRSNHK---gae
A0A1V4KEB9_PATFA/344-373             ....LSIRCPVKECDEEILYGKYSQHLSSHKEMK...
A0A1U8C9P5_MESAU/352-381             ....LVVKCPAQECNEEVSLEKYNHHVSSHKESK...
I3MY25_ICTTR/354-383                 ....LVVKCPAEECNEEISLEKYNHHVSSHKESK...
G1S8G7_NOMLE/354-383                 ....LTVKCPAKECNEEVSLEKYNHHISSHKESK...
A0A091Q6E1_LEPDC/346-375             ....LGIRCPVKECNEEVLHRKYGQHLSNHKEMK...
A0A091RIN4_9GRUI/346-375             ....LGIRCPVKECDEEILHGKYGQHLSSHKEIK...
A0A401P966_SCYTO/352-381             ....LVLRCPVTDCEVEVRLGEYSTHALDHKE--rr.
L5KYG5_PTEAL/397-426                 ....LMVKCPAQECNEEVSLEKYNHHVSSHKDSK...
G1KDK1_ANOCA/356-384                 ....PVI-CPVKDCQEEICLGKYCHHLSIHKEIK...
A0A2Y9JV89_ENHLU/354-383             ....LMVKCPAKECNKEISLEKYNHHVSSHKESK...
A0A212DHZ8_CEREH/161-190             ....LMVKCPAEECDEEVSLEKYNHHVSSHKESK...
A0A1L8GE69_XENLA/355-384             ....LLLKCTVSGCDEEISLGKYSHHISKHKETK...
A0A2I3T8S9_PANTR/354-383             ....LMVKCPAKECNEEVSLEKYNHHISSHKESK...
A0A1A6HQ99_NEOLE/400-429             ....LTVKCPAQECNEEVSLEKYNHHVSSHKESK...
G1TU62_RABIT/439-468                 ....LIVKCSAPECNEEVSLEKYNHHVSSHKE--sr.
A0A151MBE1_ALLMI/345-374             ....LTLRCPVKECDEEILLGKYGQHLPSHKELK...
A0A6P8PIW8_GEOSA/394-423             ....LVLRCTVKECGEEVSLGKYANHLSAHTETK...
A0A3Q7PJN5_CALUR/354-383             ....LMVKCPAKECNEEVSLEKYNHHVSSHKESK...
A0A6P6ICI4_PUMCO/354-383             ....LMVRCPAKECNEEVSLEKYNHHVSSHKESK...
W5LZ93_LEPOC/356-385                 ....LVIRCPAQDCDEHVRLEDYGAHTLSHQEGQ...
A0A670YKZ3_PSETE/351-380             ....LVLRCPIKGCHEEVFLEKYCQHRSNHK---gae
A0A6P3EZE1_OCTDE/354-383             ....LMVKCPAKECNEEVSLEKYNQHVSSHKESK...
A0A2K6ARB2_MACNE/354-383             ....LMVKCPAKECNQEVSLEKYNHHILSHKESK...
A0A452H4I7_9SAUR/358-387             ....LAVRCPVKECDEEVLLGKYCHHLSSHKEVK...
A0A4X2L299_VOMUR/358-387             ....LVVRCPVKDCDKEVSLEKYNQHISSHKKPK...
A0A2K5XFH0_MANLE/354-383             ....LMVKCPAKECNQEVSLEKYNHHISSHKESK...
A0A341C1J8_NEOAA/354-383             ....LMVKCPAKECNEEVSLEKYNHHVSSHKESK...
A0A672UXW5_STRHB/342-371             ....LGIRCPVKECDEEILHEKYGQHLSSHKEMK...
A0A093IWW8_DRYPU/346-375             ....LSIRCPVKECDEEISHGKYGQHLSSHKEMK...
A0A4W2E8Q3_BOBOX/354-383             ....LMVKCPAEECDEEVSLEKYNHHVSSHKESK...
A0A2I2ZGP8_GORGO/354-383             ....LMVKCPAKECNEEVSLEKYNHHISSHKESK...
A0A2Y9D8H7_TRIMA/354-383             ....LMVKCPSKECNEEVSLEKYNHHVASHKESK...
A0A0Q3LSI9_AMAAE/332-361             ....LGIRCTVKECDEEILHEKYGQHLSSHKEMK...
A0A091UWK0_NIPNI/346-375             ....LGIRCPVKECDEEILHGKYGQHLSSHKEMK...
#=GC SS_cons                         ....-EEE--STT---EEEHHHHHHHHHTS----...
#=GC seq_cons                        ....LhV+CPsKECsEEVSLEKYspHlSSHKEsK...
//
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