KEGG   Panthera leo (lion): 122199269
Entry
122199269         CDS       T10741                                 
Symbol
AP2A2
Name
(RefSeq) AP-2 complex subunit alpha-2 isoform X1
  KO
K11824  AP-2 complex subunit alpha
Organism
plez  Panthera leo (lion)
Pathway
plez04142  Lysosome biogenesis
plez04144  Endocytosis
plez04721  Synaptic vesicle cycle
plez04961  Endocrine and other factor-regulated calcium reabsorption
plez05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:plez00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    122199269 (AP2A2)
   04142 Lysosome biogenesis
    122199269 (AP2A2)
 09150 Organismal Systems
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    122199269 (AP2A2)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    122199269 (AP2A2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    122199269 (AP2A2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:plez04131]
    122199269 (AP2A2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:plez04147]
    122199269 (AP2A2)
Membrane trafficking [BR:plez04131]
 Endocytosis
  Clathrin-mediated endocytosis
   AP-2 complex
    122199269 (AP2A2)
Exosome [BR:plez04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   122199269 (AP2A2)
SSDB
Motif
Pfam: Adaptin_N Alpha_adaptin_C Alpha_adaptinC2 Cnd1 HEAT_2 HEAT_GCN1 RIX1 HEAT_EF3_N HEAT_MROH2B_1st TOR1L1_N PDS5 SUV2_M
Other DBs
NCBI-GeneID: 122199269
NCBI-ProteinID: XP_042760091
UniProt: A0A8C8YBT6
Position
D1:complement(114601809..114687192)
AA seq 936 aa
MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC
KLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL
ASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSP
DLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSA
STDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDPAVRGRLTECLETILNKAQEPPKSKKV
QHSNAKNAVLFETISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSE
FSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSI
REEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAA
KTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFHLLHSKFHLCSVPTRAL
LLSTYIKFVNLFPEVKTTIQDVLRSDSQLKNADVELQQRAVEYLRLSTVASTDILATVLE
EMPPFPERQSSILAKLKKKKGPDTATGLEEAKRERSAAVNGGPEPAPASAASTPSPSADL
LGLGAAPPAPAGPPPSSGGLLVDVFSDSPSAVAPLAPGSEDNFARFVCKNNGVLFENQLL
QIGLKSEFRQNLGRMFIFYGNKTSTQFLNFTPTLICSDDLQMNLSLQTKPVDPTVDGGAQ
VQQVVNIECVSDFTEAPVLNIQFRYGGTFQNVSVKLPITLNKFFQPTEMASQDFFQRWKQ
LSNPQQEVQNIFKAKHPMDTEITKAKIIGFGSALLEEVDPNPANFVGAGIIHTKTTQIGC
LLRLEPNLQAQMYRLTLRTSKETVSQRLCELLSEQF
NT seq 2811 nt   +upstreamnt  +downstreamnt
atgccggccgtgtcgaagggggacgggatgcggggcttggcggtcttcatctccgacatt
cgcaactgcaaaagtaaagaagcagagataaagagaataaacaaagaactggcaaacatt
agatcaaaatttaaaggtgacaaggctctcgatggctacagtaaaaagaagtacgtctgc
aagttgctgttcatcttcctcctgggtcatgacattgactttgggcacatggaggctgtg
aacctgctgagctccaacagatacacggagaagcagatcggctacctcttcatctctgtg
ctggtgaactccaacagcgagctgatccggctcatcaacaacgccatcaagaacgacctg
gccagtcggaaccccaccttcatgggcctggccctgcactgcatcgccaacgtgggcagc
cgagagatggccgaggcgtttgctggggagattccgaaaatcctcgtcgctggagacacc
atggacagcgtgaagcagagcgccgccctgtgtttgctgcgtttgtaccgaacgtctccc
gacctcgtccccatgggtgactggacgtcccgcgtggtgcacctcctcaacgaccagcac
ttgggtgtggtgaccgcggccaccagcctcattaccaccttggcccagaagaaccccgag
gagttcaagacttctgtctctctggccgtgtccaggttaagcaggattgtgacatctgca
tcaacagaccttcaggattatacctactattttgtcccggctccctggctgtccgtgaaa
cttctgaggttgctacagtgctacccacccccagaagaccctgcagtgcgaggccgcctg
accgagtgcctggagacgattctgaacaaagcccaggaaccaccaaagtcaaaaaaagtg
cagcattccaatgccaagaacgccgtgctcttcgagaccatcagcctgatcatccaccac
gacagcgagccgaacctgctggtgcgcgcctgtaaccagctgggccagttcctgcagcac
cgggagaccaacctccgctacctggccctggagagcatgtgcacgctggccagctccgag
ttctcccacgaagccgtcaagacgcacatcgagacggtcatcaacgcgctgaagacggag
cgggacgtgagtgtgcggcagcgggccgtggacctcctctacgccatgtgtgaccgcagc
aacgcccagcagattgtggccgagatgctgagctacttggagacggccgactattccatc
cgggaagagattgtgctgaaagttgccatcttggcggagaagtacgctgtggactacacg
tggtacgtggacaccatcctgaacctgatccggatcgccggcgactacgtgagcgaagag
gtgtggtaccgcgtcattcagattgtcatcaaccgcgacgacgtgcagggctacgctgcc
aagacggtgttcgaggctcttcaggccccggcgtgccacgagaacctggtcaaagtggga
ggctacatcctgggagagtttggaaacttgatagctggggaccccaggtccagccccctg
atccagttccacctgctgcactccaagttccacctgtgcagcgtccccaccagggcgctg
ctcttgtccacctacatcaagttcgtgaacctgttcccggaggtgaagaccaccattcag
gacgtgctgcgcagtgacagccagctgaagaacgccgacgtcgagctgcagcagcgggcc
gtggagtacctgcggctcagcacggtggccagcaccgacatcctggcgaccgtcctggag
gagatgccgccgtttccggagcgccagtcctccattctggccaagctcaagaagaagaag
ggcccggacacagccacgggtctggaggaggccaagcgggagaggagcgccgctgtcaac
gggggccccgagcctgccccggccagcgccgcgtccacgccttctccatcggcggacctc
ttgggtctgggggccgcgccccctgcgcctgcgggccccccaccgtcctccggcgggctg
ctcgtggatgtattctcagactcaccctctgcggtcgcgccactggctcccggctccgaa
gacaactttgccaggtttgtctgtaaaaataatggtgtgttgtttgaaaaccagttgctt
caaattggattgaagtctgaatttcggcagaatttaggtcggatgtttatattctatgga
aataagacctccacgcagttcttaaatttcactccaacactgatctgttcagacgacctt
cagatgaatctgagcttgcagaccaagcctgtggaccctaccgtggacggtggcgcgcag
gtgcagcaggtcgtcaacatagagtgtgtgtctgacttcacggaggcgcccgtcctcaac
atccagttccggtatggggggacttttcagaatgtgtccgtgaagctgcctatcactctc
aacaaatttttccagcccacagaaatggcttctcaggatttctttcagcgttggaagcag
ctgagcaatccccaacaggaagtgcagaacattttcaaagcaaagcatccgatggacaca
gaaatcaccaaagctaagatcattgggtttggttctgcgctccttgaagaagttgatccg
aatcctgcaaattttgtgggggctggcatcatccacaccaaaaccacccagattggatgc
ttgctgcgtttggagccaaatctgcaagcccagatgtaccgcctcacgctgcgcacaagt
aaagagaccgtctcccagaggttgtgcgaattgctgtcagagcagttttaa

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (12)   
   Pfam (12)   
All databases (19)   

Download RDF
DBGET integrated database retrieval system