KEGG   Perognathus longimembris pacificus (Pacific pocket mouse): 125362680
Entry
125362680         CDS       T08928                                 
Symbol
Plcb3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
plop  Perognathus longimembris pacificus (Pacific pocket mouse)
Pathway
plop00562  Inositol phosphate metabolism
plop01100  Metabolic pathways
plop04015  Rap1 signaling pathway
plop04020  Calcium signaling pathway
plop04022  cGMP-PKG signaling pathway
plop04062  Chemokine signaling pathway
plop04070  Phosphatidylinositol signaling system
plop04071  Sphingolipid signaling pathway
plop04072  Phospholipase D signaling pathway
plop04081  Hormone signaling
plop04082  Neuroactive ligand signaling
plop04261  Adrenergic signaling in cardiomyocytes
plop04270  Vascular smooth muscle contraction
plop04310  Wnt signaling pathway
plop04371  Apelin signaling pathway
plop04540  Gap junction
plop04611  Platelet activation
plop04613  Neutrophil extracellular trap formation
plop04621  NOD-like receptor signaling pathway
plop04713  Circadian entrainment
plop04720  Long-term potentiation
plop04723  Retrograde endocannabinoid signaling
plop04724  Glutamatergic synapse
plop04725  Cholinergic synapse
plop04726  Serotonergic synapse
plop04728  Dopaminergic synapse
plop04730  Long-term depression
plop04742  Taste transduction
plop04750  Inflammatory mediator regulation of TRP channels
plop04911  Insulin secretion
plop04912  GnRH signaling pathway
plop04915  Estrogen signaling pathway
plop04916  Melanogenesis
plop04918  Thyroid hormone synthesis
plop04919  Thyroid hormone signaling pathway
plop04921  Oxytocin signaling pathway
plop04922  Glucagon signaling pathway
plop04924  Renin secretion
plop04925  Aldosterone synthesis and secretion
plop04926  Relaxin signaling pathway
plop04927  Cortisol synthesis and secretion
plop04928  Parathyroid hormone synthesis, secretion and action
plop04929  GnRH secretion
plop04933  AGE-RAGE signaling pathway in diabetic complications
plop04934  Cushing syndrome
plop04935  Growth hormone synthesis, secretion and action
plop04961  Endocrine and other factor-regulated calcium reabsorption
plop04970  Salivary secretion
plop04971  Gastric acid secretion
plop04972  Pancreatic secretion
plop04973  Carbohydrate digestion and absorption
plop05010  Alzheimer disease
plop05016  Huntington disease
plop05017  Spinocerebellar ataxia
plop05022  Pathways of neurodegeneration - multiple diseases
plop05142  Chagas disease
plop05143  African trypanosomiasis
plop05146  Amoebiasis
plop05163  Human cytomegalovirus infection
plop05200  Pathways in cancer
plop05415  Diabetic cardiomyopathy
plop05417  Lipid and atherosclerosis
Module
plop_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:plop00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    125362680 (Plcb3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    125362680 (Plcb3)
   04310 Wnt signaling pathway
    125362680 (Plcb3)
   04371 Apelin signaling pathway
    125362680 (Plcb3)
   04020 Calcium signaling pathway
    125362680 (Plcb3)
   04070 Phosphatidylinositol signaling system
    125362680 (Plcb3)
   04072 Phospholipase D signaling pathway
    125362680 (Plcb3)
   04071 Sphingolipid signaling pathway
    125362680 (Plcb3)
   04022 cGMP-PKG signaling pathway
    125362680 (Plcb3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    125362680 (Plcb3)
   04081 Hormone signaling
    125362680 (Plcb3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    125362680 (Plcb3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    125362680 (Plcb3)
   04613 Neutrophil extracellular trap formation
    125362680 (Plcb3)
   04621 NOD-like receptor signaling pathway
    125362680 (Plcb3)
   04062 Chemokine signaling pathway
    125362680 (Plcb3)
  09152 Endocrine system
   04911 Insulin secretion
    125362680 (Plcb3)
   04922 Glucagon signaling pathway
    125362680 (Plcb3)
   04929 GnRH secretion
    125362680 (Plcb3)
   04912 GnRH signaling pathway
    125362680 (Plcb3)
   04915 Estrogen signaling pathway
    125362680 (Plcb3)
   04921 Oxytocin signaling pathway
    125362680 (Plcb3)
   04926 Relaxin signaling pathway
    125362680 (Plcb3)
   04935 Growth hormone synthesis, secretion and action
    125362680 (Plcb3)
   04918 Thyroid hormone synthesis
    125362680 (Plcb3)
   04919 Thyroid hormone signaling pathway
    125362680 (Plcb3)
   04928 Parathyroid hormone synthesis, secretion and action
    125362680 (Plcb3)
   04916 Melanogenesis
    125362680 (Plcb3)
   04924 Renin secretion
    125362680 (Plcb3)
   04925 Aldosterone synthesis and secretion
    125362680 (Plcb3)
   04927 Cortisol synthesis and secretion
    125362680 (Plcb3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    125362680 (Plcb3)
   04270 Vascular smooth muscle contraction
    125362680 (Plcb3)
  09154 Digestive system
   04970 Salivary secretion
    125362680 (Plcb3)
   04971 Gastric acid secretion
    125362680 (Plcb3)
   04972 Pancreatic secretion
    125362680 (Plcb3)
   04973 Carbohydrate digestion and absorption
    125362680 (Plcb3)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    125362680 (Plcb3)
  09156 Nervous system
   04724 Glutamatergic synapse
    125362680 (Plcb3)
   04725 Cholinergic synapse
    125362680 (Plcb3)
   04728 Dopaminergic synapse
    125362680 (Plcb3)
   04726 Serotonergic synapse
    125362680 (Plcb3)
   04720 Long-term potentiation
    125362680 (Plcb3)
   04730 Long-term depression
    125362680 (Plcb3)
   04723 Retrograde endocannabinoid signaling
    125362680 (Plcb3)
  09157 Sensory system
   04742 Taste transduction
    125362680 (Plcb3)
   04750 Inflammatory mediator regulation of TRP channels
    125362680 (Plcb3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    125362680 (Plcb3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    125362680 (Plcb3)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    125362680 (Plcb3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    125362680 (Plcb3)
   05142 Chagas disease
    125362680 (Plcb3)
   05143 African trypanosomiasis
    125362680 (Plcb3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    125362680 (Plcb3)
   05016 Huntington disease
    125362680 (Plcb3)
   05017 Spinocerebellar ataxia
    125362680 (Plcb3)
   05022 Pathways of neurodegeneration - multiple diseases
    125362680 (Plcb3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    125362680 (Plcb3)
   05415 Diabetic cardiomyopathy
    125362680 (Plcb3)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    125362680 (Plcb3)
   04934 Cushing syndrome
    125362680 (Plcb3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:plop04131]
    125362680 (Plcb3)
Enzymes [BR:plop01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     125362680 (Plcb3)
Membrane trafficking [BR:plop04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    125362680 (Plcb3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    125362680 (Plcb3)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PI-PLC-Y PH_14 PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 125362680
NCBI-ProteinID: XP_048217479
Position
13:57388723..57406905
AA seq 1232 aa
MAGARPGVHALQLEPPTVVETLRRGSKFIKWDEEASSRNLVTLRVDPNGFFLYWTGPNME
VDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDARLEEKLMTVVAGPDPVNTTFLNF
MAVQDDTVKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS
ADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPY
LTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKYEPNQQFLERDQMSMEGFSRYL
GGEENGILPLEALDLSMDMTQPLSSYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRC
VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAK
QQAKMAEYCRSIFGDALLIDPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHRPSTGVPGS
SVRKRPLEQSNSALSEGSAATEPSSPQLGSPSSDSCPGLSNGEEMGLEKPRLEPQKSLGE
ESLNRGPDVLGPADREDDEEEEEEEESADPKKPTTDEGTASSEVNATEEMSTLVNYIEPV
KFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPLEFVEYNKQQLSRIYPKGTRVDSSNYM
PQLFWNVGCQLVALNFQTLDVPMQLNAGAFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIV
DGIVANALRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRRYRTRTSQGNSFNPVWDEEP
FDFPKVVLPTLASLRIAAFEEGGRFVGHRILPVSAVRSGYHYVCLRNEANQPLCLPALLI
YTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQAGPESSQESQSQQP
GSQISSNPTPCPLDSSPRRPPGPATSPTNTSLSSPGQRDDLIASILSEVAPTPLEELRGH
KSLVKLRSRQERDLRELCKKHQRKAVALTRRLLDGLAQARAEGRCRPAPGVPGGAADGED
VKEEDEAKQFREFQNRQVQSLLELREAQADVEAERRLEHLRQAQQRLREIVLDAHTTQFK
RLKELNEREKKELQKILDRKRHNSISEAKTREKHKKEAELTEINRRHITESVNSIRRLEE
AQKQRHDRLVAGQQQVLQQLAEEEPKLLAQLSQECQEQRARLPQEIRRSLLGETPGLGDG
SLVACASNGHAPGSGGHLSGADSESQEENTHL
NT seq 3699 nt   +upstreamnt  +downstreamnt
atggcgggcgccaggcccggcgtccacgcgctgcagctggagccgcccaccgtggtggag
accctgcggcgcgggagtaagttcatcaaatgggacgaggaggcctccagtcgaaacctg
gtgaccctgcgtgtggaccccaatggcttttttttgtactggacaggacccaatatggag
gtggacacactggacatcagttcaatcagggacactcgcacgggccgctatgcccgcctg
cccaaggaccccaagattcgggaagtgctaggctttgggggcccagatgcccggctggag
gagaagctgatgacggtggtggctgggccagacccggtgaacaccacgttcctgaacttc
atggctgtgcaggatgacacggtgaaggtctggtctgaggagctgtttaagctggctatg
aacatcctggctcagaacgcctctcggaataccttcctgcgtaaagcatacacaaaacta
aagctgcaggtgaaccaggacgggcgaattccggtcaagaacatcctgaagatgttctca
gcggacaagaagcgggtggagacggcgttggaatcttgcggcctcaacttcaaccggagt
gagtccatccggccggacgagttttccctggaaatcttcgagcggttcctgaacaagctg
tgtctgcggccggacattgacaagatcctgctggagataggggccaagggcaagccgtac
ctgacgctggagcagctcatggacttcatcaaccagaagcagagggacccgaggctgaat
gaggttctgtacccacccctgcggccctcacaggcccggctgctcatcgagaagtatgag
cccaaccagcagttcctggagcgcgaccagatgtccatggagggcttcagccgctacctg
ggtggggaggagaacggcatcttgccactggaggccttggatctgagcatggacatgacg
cagccgctgagctcctacttcatcaactcctcccacaacacctatctcaccgccgggcag
ctggcggggacctcgtcggtggagatgtaccgccaggcgctgctgtggggctgccgctgc
gtggagctggacgtgtggaaggggcggccccccgaagaggagcccttcatcacccacggc
ttcaccatgaccaccgaggtgcccctgcgcgacgtgctggaggccatcgccgagaccgcc
ttcaagacctcgccctaccccgtcatcctctccttcgagaaccacgtggactcggcgaag
cagcaggccaagatggccgagtactgccgctccatctttggggacgcgttgctcattgac
cccctggacaagtacccgctggccccgggggtccccctgcccagccctcaagacctgatg
ggccgcatcctggtgaagaacaagaagcggcaccggcccagcacgggggtccccggcagc
tccgtgcgcaagcggcccctggagcagagcaactcggcactgagcgaaggctccgccgcc
accgagccctcctcaccccagctcgggtcccccagctctgacagctgcccgggcctgagc
aatggggaggagatgggactggagaaacccagactggagccgcagaagtccctaggggag
gagagcctgaaccggggccctgacgttctcggacctgccgaccgggaggatgacgaggag
gaggaggaggaggaggaatcggcagaccccaaaaagccaaccacagatgagggcaccgcc
agcagtgaggtcaacgccaccgaggagatgtcaactcttgtcaactacatcgagcctgtc
aagttcaagtccttcgaggccgctcgcaagaggaacaagtgcttcgagatgtcgtccttc
gtggagaccaaggccatggagcagctgaccaagagccccttggagtttgtggaatacaac
aagcagcagctgagccgcatctaccccaagggcacgcgcgtggactcctccaactacatg
ccccagctcttctggaacgtgggctgccagctcgttgccctcaacttccaaaccctggac
gtgcccatgcagctcaacgcgggcgcgtttgagtacaacgggcgaagcgggtacctgctg
aagcccgagttcatgaggcggcctgacaagtcctttgaccccttcaccgaggtcatcgtg
gatggcattgtggccaacgccctgcgggtcaaggtgatctcggggcagttcctgtccgac
aggaaggtgggcatctacgtggaggtggatatgttcggtctcccagtggacacgcggcgc
agataccgcacccggacgtcccaggggaactcgttcaaccccgtgtgggacgaggagccc
ttcgacttccccaaggtggtgctgcccacgctggcctcgcttcgcatcgcagcgtttgag
gaaggcggcagattcgtggggcaccggatcttgcccgtctctgccgtccgctcagggtac
cactatgtctgcctgcgaaatgaagccaaccagccgctctgcctgccagccctgctcatc
tacaccgaggcctccgactacatccccgacgaccaccaggactacgcagaggccctgatc
aaccccatcaagcacgtcagcctgatggaccagcgggccaagcagctggccgccctcatc
ggcgagagcgaggctcaggctggcccagagtcaagccaggagtcccagtctcagcaaccc
gggtcccagatctcttcaaaccccaccccgtgcccactggacagcagcccccgccggccc
ccaggtcctgcaacctcgcccaccaacacctccctcagcagcccagggcagcgggacgat
ctcatcgccagcatcctttcagaggtggctcccacccctctggaagagctccggggccac
aagtccctagtgaagctgcggagtcggcaggagcgcgacctgcgggagctctgcaagaag
catcagcggaaggccgtggccctcacccgccgcttgctcgacggcctggcccaggcgcgg
gccgagggcaggtgccggcccgcgcccggcgtcccgggcggggccgctgatggggaggac
gtgaaggaagaagatgaggcgaagcagtttcgagagttccagaacaggcaggtgcagagc
ttgctggagctgagggaggcccaggcagacgtggaggccgagaggaggctggagcacctg
agacaggcccagcagcgactcagggagatcgtcctggatgcacatacaactcagttcaaa
agactgaaggagctgaacgagagggagaagaaagagctgcagaagattctggataggaaa
cgccacaatagtatctctgaggccaagacgagagagaaacataagaaggaggcggagctg
acagaaatcaatcggcggcacatcaccgagtcggtcaactccatccgccggctggaggag
gcccagaagcagcggcatgaccgcctggtggctgggcagcagcaggtcctccagcagctg
gcagaagaggagcccaagctgctagctcagctgagccaggagtgtcaggagcagcgggcc
cggctgccccaggagatccgcaggagcctgctgggcgagacgccaggcctgggggacggg
tccctggtggcctgcgccagcaacggccatgcgccagggagcggcgggcatctgtccggc
gccgactcggagagccaggaggagaacacgcacctctga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (7)   
   Pfam (7)   
All databases (13)   

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