KEGG   Peromyscus maniculatus bairdii (prairie deer mouse): 102920318
Entry
102920318         CDS       T11302                                 
Symbol
Plcb2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
pmav  Peromyscus maniculatus bairdii (prairie deer mouse)
Pathway
pmav00562  Inositol phosphate metabolism
pmav01100  Metabolic pathways
pmav04015  Rap1 signaling pathway
pmav04020  Calcium signaling pathway
pmav04022  cGMP-PKG signaling pathway
pmav04062  Chemokine signaling pathway
pmav04070  Phosphatidylinositol signaling system
pmav04071  Sphingolipid signaling pathway
pmav04072  Phospholipase D signaling pathway
pmav04081  Hormone signaling
pmav04082  Neuroactive ligand signaling
pmav04261  Adrenergic signaling in cardiomyocytes
pmav04270  Vascular smooth muscle contraction
pmav04310  Wnt signaling pathway
pmav04371  Apelin signaling pathway
pmav04540  Gap junction
pmav04611  Platelet activation
pmav04613  Neutrophil extracellular trap formation
pmav04621  NOD-like receptor signaling pathway
pmav04713  Circadian entrainment
pmav04720  Long-term potentiation
pmav04723  Retrograde endocannabinoid signaling
pmav04724  Glutamatergic synapse
pmav04725  Cholinergic synapse
pmav04726  Serotonergic synapse
pmav04728  Dopaminergic synapse
pmav04730  Long-term depression
pmav04742  Taste transduction
pmav04750  Inflammatory mediator regulation of TRP channels
pmav04911  Insulin secretion
pmav04912  GnRH signaling pathway
pmav04915  Estrogen signaling pathway
pmav04916  Melanogenesis
pmav04918  Thyroid hormone synthesis
pmav04919  Thyroid hormone signaling pathway
pmav04921  Oxytocin signaling pathway
pmav04922  Glucagon signaling pathway
pmav04924  Renin secretion
pmav04925  Aldosterone synthesis and secretion
pmav04926  Relaxin signaling pathway
pmav04927  Cortisol synthesis and secretion
pmav04928  Parathyroid hormone synthesis, secretion and action
pmav04929  GnRH secretion
pmav04933  AGE-RAGE signaling pathway in diabetic complications
pmav04934  Cushing syndrome
pmav04935  Growth hormone synthesis, secretion and action
pmav04961  Endocrine and other factor-regulated calcium reabsorption
pmav04970  Salivary secretion
pmav04971  Gastric acid secretion
pmav04972  Pancreatic secretion
pmav04973  Carbohydrate digestion and absorption
pmav05010  Alzheimer disease
pmav05016  Huntington disease
pmav05017  Spinocerebellar ataxia
pmav05022  Pathways of neurodegeneration - multiple diseases
pmav05142  Chagas disease
pmav05143  African trypanosomiasis
pmav05146  Amoebiasis
pmav05163  Human cytomegalovirus infection
pmav05200  Pathways in cancer
pmav05415  Diabetic cardiomyopathy
pmav05417  Lipid and atherosclerosis
Module
pmav_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:pmav00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102920318 (Plcb2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    102920318 (Plcb2)
   04310 Wnt signaling pathway
    102920318 (Plcb2)
   04371 Apelin signaling pathway
    102920318 (Plcb2)
   04020 Calcium signaling pathway
    102920318 (Plcb2)
   04070 Phosphatidylinositol signaling system
    102920318 (Plcb2)
   04072 Phospholipase D signaling pathway
    102920318 (Plcb2)
   04071 Sphingolipid signaling pathway
    102920318 (Plcb2)
   04022 cGMP-PKG signaling pathway
    102920318 (Plcb2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    102920318 (Plcb2)
   04081 Hormone signaling
    102920318 (Plcb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    102920318 (Plcb2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102920318 (Plcb2)
   04613 Neutrophil extracellular trap formation
    102920318 (Plcb2)
   04621 NOD-like receptor signaling pathway
    102920318 (Plcb2)
   04062 Chemokine signaling pathway
    102920318 (Plcb2)
  09152 Endocrine system
   04911 Insulin secretion
    102920318 (Plcb2)
   04922 Glucagon signaling pathway
    102920318 (Plcb2)
   04929 GnRH secretion
    102920318 (Plcb2)
   04912 GnRH signaling pathway
    102920318 (Plcb2)
   04915 Estrogen signaling pathway
    102920318 (Plcb2)
   04921 Oxytocin signaling pathway
    102920318 (Plcb2)
   04926 Relaxin signaling pathway
    102920318 (Plcb2)
   04935 Growth hormone synthesis, secretion and action
    102920318 (Plcb2)
   04918 Thyroid hormone synthesis
    102920318 (Plcb2)
   04919 Thyroid hormone signaling pathway
    102920318 (Plcb2)
   04928 Parathyroid hormone synthesis, secretion and action
    102920318 (Plcb2)
   04916 Melanogenesis
    102920318 (Plcb2)
   04924 Renin secretion
    102920318 (Plcb2)
   04925 Aldosterone synthesis and secretion
    102920318 (Plcb2)
   04927 Cortisol synthesis and secretion
    102920318 (Plcb2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102920318 (Plcb2)
   04270 Vascular smooth muscle contraction
    102920318 (Plcb2)
  09154 Digestive system
   04970 Salivary secretion
    102920318 (Plcb2)
   04971 Gastric acid secretion
    102920318 (Plcb2)
   04972 Pancreatic secretion
    102920318 (Plcb2)
   04973 Carbohydrate digestion and absorption
    102920318 (Plcb2)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    102920318 (Plcb2)
  09156 Nervous system
   04724 Glutamatergic synapse
    102920318 (Plcb2)
   04725 Cholinergic synapse
    102920318 (Plcb2)
   04728 Dopaminergic synapse
    102920318 (Plcb2)
   04726 Serotonergic synapse
    102920318 (Plcb2)
   04720 Long-term potentiation
    102920318 (Plcb2)
   04730 Long-term depression
    102920318 (Plcb2)
   04723 Retrograde endocannabinoid signaling
    102920318 (Plcb2)
  09157 Sensory system
   04742 Taste transduction
    102920318 (Plcb2)
   04750 Inflammatory mediator regulation of TRP channels
    102920318 (Plcb2)
  09159 Environmental adaptation
   04713 Circadian entrainment
    102920318 (Plcb2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102920318 (Plcb2)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    102920318 (Plcb2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    102920318 (Plcb2)
   05142 Chagas disease
    102920318 (Plcb2)
   05143 African trypanosomiasis
    102920318 (Plcb2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102920318 (Plcb2)
   05016 Huntington disease
    102920318 (Plcb2)
   05017 Spinocerebellar ataxia
    102920318 (Plcb2)
   05022 Pathways of neurodegeneration - multiple diseases
    102920318 (Plcb2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102920318 (Plcb2)
   05415 Diabetic cardiomyopathy
    102920318 (Plcb2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    102920318 (Plcb2)
   04934 Cushing syndrome
    102920318 (Plcb2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pmav04131]
    102920318 (Plcb2)
Enzymes [BR:pmav01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     102920318 (Plcb2)
Membrane trafficking [BR:pmav04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    102920318 (Plcb2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    102920318 (Plcb2)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 102920318
NCBI-ProteinID: XP_076426466
Ensembl: ENSPEMG00000002578
Position
4:complement(96332805..96354611)
AA seq 1172 aa
MSLLNPVLLPPNVKAYLSQGERFIKWDDETSIASPVILRVDPKGYYLYWTYQSKEMEFLD
ITSIRDTRFGKFAKTPKSQKLREVFNMDFPDNHFLLKALTVVSGPDMVDLTFHNFVSYKE
NVGKDWAEDILALTKHPMTANAPRSTFLDKILVKLKMQLNPEGKIPVKNFFQMFPADRKR
VEAALSACHLAKGKNDAINPEDFPESVYKSFLMNLCPRPEIDEIFTSYHAKAKPYMTKEH
LTKFINQKQRDSRLNSLLFPPARPEQVQTLIDKYEPSGINVQRGQLSPEGMVWFLCGPEN
SALAHNTLLLHHDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLSGCRCVELDC
WKGKPPDEEPIITHGFTMTTDILFKEAIEAIAESAFKTSPYPVILSFENHVDSPRQQAKM
AEYCRTMFGETLLTDPLEKFPLKPGIPLPSPEDLRGKILIKNKKNQFSGPASPSSPGGQK
PGGEAEGSCPSSVPTEEDTVWTSEDRTEVEEEEEVEEEEEEEESGNLDEEEIKKMQSDEG
TAGLEVTAYEEMSSLVNYIQPTKFISFEFSAQKNRSYVISSFTELKAYELLSKASMQFVD
YNKRQMSRVYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGY
LLKHEFMRRLDKQFNPFSVDRIDVVVATTLSITVISGQFLSERSVRTYVEVELFGLPGDP
KRRYRTKLSPTTNSINPVWKEEPFVFEKILMPELASLRIAVMEEGNKFLGHRIIPINALH
SGYHHLCLRSESNMPLTMPALFVFLEMKDYVPDTWADLTVALANPIKYFNAHDKKSMKLK
EVTGSLPEKPFSSGIPIPSQSNGASVPAGNGSTEPQTTSLEELQELKGVVKLQRRHEKEL
RELERRGARRWEELLQRGTAQLAELGAPAAGCKLRPGKGSRKKRTLPCEETVGVAPSELP
EGADPRVQELKSRLEQELKQQGEEQYLSVLKRKEQHVTEHIAKMMELARERQAAELKTFK
ETSETDTKEMKKRLEAKRLERIQAMTRVTTDKVAQERLKREINNSHIQEVVQAIKQMTET
LERHQEKLEGKQTACLEQIRELEKQFQEKALAEYEARMKGLETEVKESVRACFKACFPSE
TEDRPEGACEASKELCPQEPLMNKADTQESRL
NT seq 3519 nt   +upstreamnt  +downstreamnt
atgtctctgctcaaccctgtcctgttgccccctaacgtgaaggcgtatctgagtcaagga
gagcgcttcatcaagtgggacgacgaaacttcaattgcctctccagttatcctccgtgtg
gaccccaagggctattacttatactggacatatcagagtaaggagatggagtttctggac
atcacgagcatccgagacactcgctttggcaagtttgccaagacgcccaagagccagaaa
ctccgggaggtcttcaacatggactttccagacaaccacttcctgctgaaagcactcacc
gtggtgtccggccctgacatggtggacctcaccttccacaacttcgtctcttacaaggag
aatgtgggcaaggactgggccgaggatatactggctctcaccaaacaccccatgacagcc
aatgctccccgaagcactttcctagacaagatcctggtgaagctgaagatgcaactcaac
cctgaagggaagattcctgtgaagaattttttccagatgtttccggctgatcgcaaacga
gtagaagctgccctcagtgcttgtcaccttgcaaaaggcaagaacgatgccatcaatccc
gaggacttcccagagtctgtgtacaagagcttcctcatgaatctctgtcctcggccagaa
attgacgagatcttcacttcttaccatgctaaagctaagccctacatgaccaaggagcac
ctgaccaaattcatcaaccagaagcagcgagactctcggctcaactccctgctgttcccg
ccagcccggcccgagcaggtgcagacgctcatcgacaagtacgaacccagcggcatcaat
gtgcagaggggccagctgtcaccagagggcatggtctggtttctctgcggaccagagaac
agtgcgctagcccacaataccctgctgctccaccacgacatgacccagccgctgaatcac
tacttcatcaactcctcacacaacacctacctgacagccggccagttttcaggcctttcc
tcggctgagatgtaccgccaggtgctcctgtctggctgccgttgtgtggagttggactgt
tggaaggggaagccccccgacgaggagcccattatcacccatggcttcaccatgaccacc
gatatcttgttcaaggaagcaatcgaagccattgcagaaagtgccttcaagacctccccc
tatcctgtcatcttgtcgtttgaaaaccacgtggactcaccccgccaacaggctaagatg
gccgagtactgcaggactatgtttggagaaaccctgctcacagatcccctggaaaaattc
cctctgaaacctggcatccctctgcccagcccggaggacctccggggcaagatcctcatt
aagaataagaagaaccagttttccggaccagcatcccccagctcccctggtgggcagaaa
cctggtggggaggccgagggcagctgcccgtctagtgtccccactgaggaggacacagtg
tggacctcggaggaccggactgaggtggaggaggaggaggaggtggaggaagaggaggaa
gaggaggagtcaggaaacctggatgaagaagagataaagaagatgcagtcggatgagggt
acagcaggcttggaggtgaccgcttatgaggaaatgtccagccttgtcaattacatccag
cccaccaagttcatctccttcgagttctctgcacagaagaacagaagttacgtcatctcc
tccttcacggagctcaaggcctacgagctgctctcgaaggcctccatgcagtttgtggac
tacaataaacggcagatgagccgagtgtaccccaagggcacacgcatggactcttccaac
tacatgccccagatgttctggaatgctggctgccagatggttgccctcaatttccaaaca
atggacctgccaatgcagcagaacatggcactgttcgagttcaatgggcagagtggatac
ctcctgaagcatgagttcatgcgcaggctggacaagcagttcaaccccttctcggtggac
cgcattgacgtggtggtagccaccaccctctccatcacggtgatctctgggcagttcctg
tcagagcgcagtgttcgcacctatgtggaagtggaactcttcggcctcccaggggacccc
aagaggcgctatcgcaccaagctgtcacctacgaccaactccatcaatcctgtctggaaa
gaggagccctttgtctttgagaagatcttgatgcctgagctggcctccctcaggatcgct
gtgatggaagaaggcaacaaatttctcgggcaccgaatcatccccatcaacgccttacat
tctgggtaccaccacttgtgcctgcgcagtgagagcaacatgccgcttaccatgcccgcc
ctctttgtcttcctggagatgaaggactatgtacccgacacatgggcagatcttacagtg
gcactcgccaaccccatcaagtacttcaatgcccatgacaagaagtctatgaagctcaag
gaggtgacaggaagtttgcctgagaaacccttctcatccgggattcctattcccagccag
tccaatggagcgtcagtcccagcaggcaacgggtcaacagagccccagaccaccagcttg
gaggagctgcaggagctgaagggcgtggtgaagctgcagcggagacacgagaaggagctt
cgcgagttggagcggcgtggagccaggcgctgggaagagctgctgcagcgtggcaccgca
cagctggcagaactcggagctccagcggcgggctgcaagctccgcccgggcaagggctcc
cgcaagaagaggaccctgccctgtgaggagacggtcggggtggcgcctagcgagctgccc
gagggtgcagacccgcgcgtgcaggagctgaagagcaggctggagcaggagctgaagcag
cagggcgaggagcagtacctctctgtcctcaagcgcaaggagcagcacgtgaccgagcac
atcgccaagatgatggagctggccagagagaggcaggctgctgaactcaagaccttcaag
gagacctcagaaacggacaccaaagagatgaagaaaagactggaggccaagaggctggaa
cggatccaagccatgaccagagtcaccacagacaaggtggcccaggagaggctcaagaga
gagatcaacaactcccacatccaggaagtggtgcaggctatcaagcagatgaccgagacc
ctggagcggcaccaggagaagctggaagggaagcagaccgcctgcctggagcagatccgg
gagctggaaaagcagttccaggagaaggcgctggctgagtatgaggccaggatgaagggc
ctggagacggaagtgaaggaatcagtgagggcttgcttcaaggcctgcttcccctctgaa
acagaagacaggcctgagggggcctgcgaggcctccaaagagttgtgtccacaggaacca
ctcatgaacaaagcagacacccaggagagccgcctctga

  All links  
Gene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (12)   

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