KEGG   Pimephales promelas (fathead minnow): 120477635
Entry
120477635         CDS       T08155                                 
Symbol
plcb3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
pprm  Pimephales promelas (fathead minnow)
Pathway
pprm00562  Inositol phosphate metabolism
pprm01100  Metabolic pathways
pprm04020  Calcium signaling pathway
pprm04070  Phosphatidylinositol signaling system
pprm04081  Hormone signaling
pprm04082  Neuroactive ligand signaling
pprm04261  Adrenergic signaling in cardiomyocytes
pprm04270  Vascular smooth muscle contraction
pprm04310  Wnt signaling pathway
pprm04371  Apelin signaling pathway
pprm04540  Gap junction
pprm04621  NOD-like receptor signaling pathway
pprm04912  GnRH signaling pathway
pprm04916  Melanogenesis
Module
pprm_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:pprm00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    120477635 (plcb3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    120477635 (plcb3)
   04371 Apelin signaling pathway
    120477635 (plcb3)
   04020 Calcium signaling pathway
    120477635 (plcb3)
   04070 Phosphatidylinositol signaling system
    120477635 (plcb3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    120477635 (plcb3)
   04081 Hormone signaling
    120477635 (plcb3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    120477635 (plcb3)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    120477635 (plcb3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    120477635 (plcb3)
   04916 Melanogenesis
    120477635 (plcb3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    120477635 (plcb3)
   04270 Vascular smooth muscle contraction
    120477635 (plcb3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pprm04131]
    120477635 (plcb3)
Enzymes [BR:pprm01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     120477635 (plcb3)
Membrane trafficking [BR:pprm04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    120477635 (plcb3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    120477635 (plcb3)
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PI-PLC-Y PH_14 PLCB1-4-like_EFh EF-hand_like TEN_TERT
Other DBs
NCBI-GeneID: 120477635
NCBI-ProteinID: XP_039525236
Position
Unknown
AA seq 1260 aa
MAGAKPGVHALQLKPVSVHEVLKRGSKFIKWDEDSNIPPSLVTLKVDPDGFFLYWSGGTN
MEYEILDICHIRDTRTGRYSKMPKDPRIREMLGLGRGEGNSDSKLLTVVYGNDLVNISFL
NFQAVMDGYCKVWTDELFKLATNTLSQNASRNTFLMKAYTKLKLQVNQDGKIPVKNIMKM
FSDKKRVENALEHCGLVNSRVISRAQGDHGIKLEDFTWEMFQNFLSKLCPRPEVERVFVE
LGSRGKPFLSLDQLMDYINRRQRDSRLNEVLYPPLKREQVRQLMEKYETNVSQLERDQIS
LMAFAKYLGGEENSVVPYERLDIIDDMNQPLSHYFINSSHNTYLTVGQLTGLSSVEMYRQ
VLLTGCRCIELDCWKGRPPDEEPIITHGFTMTTEIPFKEVIEAIAESAFKTSQYPLILSF
ENHVDSAKQQAKMAEYCRSMFGDALLIDPLDKYPLEPGQPLPSPQDLMGKILIKNKKKHH
HRASNGGSIRRKDGTDEQSSPLNDCPLSDGEVGQNMSNGGEKLAERMAKDLDIRKSIDGE
SDEEEEEEPIPDPKKHNNTDEGTAYSEVNATEEMSTLVNYIEPVKFKSFEAACKRNKYFE
MSSFVETKGMDTMKNYPGEFVEYNKKQLSRIYPKGTRVDSSNYMPQLFWNVGCQMVALNF
QTLDLPMQLNMGVFEYNGNCGYLLKPEFMRRTDKHFDPFTMDIVDGIVANTVRVKIISGQ
FLSDKKASVYVEIDMFGLPADTKRKYRTKTSNNNSLDPIWDDEAYVFNKVVLPTLASLRL
AVFEENGKFLGHRILPVSALRPGYHYISLKNELNQPLMLASLLVYTEARDYIPNEHQEYA
EALTNPIKHLSLLAQREKQLLALMEDLPVEVKKEMLRNQDKTEKLDEGDSNSGCVPSADP
FCPLPSSPTLPPVVSEVMNSPPSGPKEDLVNNILKVIEPQSIDELKQQNSYQKLKKKQSK
ELKELSKKHVKKLWALSKEQKTRCTQLNSDLQRKRSQMEKRLRSSLKKNGSEEPAQRELK
ELDLELERQTEQFREEQLQELLALRQAQHQTEKEAKQCHLKEANQKLREIAQDCQASQIK
KLKEVCDKEKKELQKILERKRLNSIIEAKKSEKEIRELTEINRKHINESVSLIRQLEVSQ
GKRQEKLKALHKDILQKIEEEVPLDQARLTLECEAEMTLLPGEVSRFMQEVESKGSRKDT
LIGQANDSLSSGPSSNCSTPPYTSPNHTWGSNMGNAVSMLESSSTSNTPVKSETDTTGVY
NT seq 3783 nt   +upstreamnt  +downstreamnt
atggccggggcgaaaccgggagtacacgcgttacagctcaaaccggtgtctgtccatgag
gtgctcaaacgggggagcaagtttatcaagtgggacgaggactccaacatcccacccagc
cttgtcaccctcaaagttgacccagatggattcttcctctactggtctggagggaccaac
atggaatatgaaatcctggacatctgtcatatcagggataccaggacggggagatattcc
aagatgccaaaggacccacgtatacgtgaaatgttgggtttgggcagaggagaagggaac
tccgactcaaagctgctaactgttgtctacggcaacgacctggtcaacatctccttcctt
aacttccaagctgtgatggatggctattgcaaggtgtggactgacgaactgtttaaactt
gccacaaacacactctcccagaatgcttcccgcaacaccttcttaatgaaagcttacaca
aagctgaagctgcaggtaaatcaggatgggaaaatcccagtgaagaacatcatgaaaatg
ttctcggataagaaacgtgtggagaatgcgctggagcactgcggtctggtcaatagcaga
gtaatcagtcgagcacagggggatcatggtataaagctagaggactttacctgggaaatg
ttccagaacttcctcagcaaactatgtcccagaccagaggtggagcgtgtctttgtggag
cttggctctagagggaagcccttcttgtctctggatcagttgatggactatataaatcgg
agacagagagattctcgactaaatgaggttctttacccaccgctcaagcgagaacaggtc
cgccaactcatggagaaatatgaaaccaacgtcagccagctggaaagagaccagatctcc
ctaatggccttcgcaaagtatcttggtggtgaagagaactctgtggttccttatgagagg
ttggacatcatcgatgatatgaaccaacccctttcccactatttcatcaactcttcacac
aacacgtacctcacagtggggcagttgacgggcctgtcgtcagtagagatgtaccggcag
gtgttgctgacagggtgtcgctgtatagagctagactgctggaagggccgcccacctgac
gaagagccaatcatcacgcacggtttcacaatgacaactgagattccattcaaggaggtg
attgaagctattgctgaaagtgcattcaagacgtcccaatatcctctgatcctgtccttt
gagaatcatgtggactcggcaaagcaacaggctaaaatggcagaatactgtcgctctatg
ttcggggacgcgctactcattgatccactagacaaatatccgctggaacctggtcaacca
ctgccaagcccccaggacctgatggggaaaatcttgatcaagaacaagaagaaacaccac
cacagggcatcaaacggtgggagcattagacgcaaggacggaacagacgaacagtcctcg
cctttgaatgattgtccgttgtctgatggggaggtgggccagaacatgtccaatgggggt
gagaagcttgcagagaggatggccaaagaccttgatatccgcaagtctattgatggagag
agcgatgaagaggaggaagaggaacccattccagatccaaagaaacacaacaacactgat
gagggtactgcgtacagtgaggtgaacgctacagaggagatgtccacattggtcaactac
atagaaccagtcaaattcaaatcctttgaggcggcctgcaagaggaataagtattttgag
atgtcatcttttgtggagaccaaaggcatggatactatgaagaattatcccggcgagttt
gttgaatacaataaaaagcagttaagtcgcatctaccccaaagggacccgtgtggattcc
agtaactatatgccacagctcttctggaacgtgggctgccagatggtggcgctaaacttc
caaactctcgacttgccaatgcagctgaacatgggggtgtttgaatataacggcaactgt
gggtatctactgaagccagagttcatgaggcgcacagacaaacactttgatccctttact
atggacattgtggatggcattgtagccaacacagttagagtcaagatcatctcaggccag
tttctgagtgataagaaggccagtgtttacgtggagatagacatgtttggacttcctgca
gacactaaaagaaaatatcgaacgaaaacttctaacaacaactctctggacccaatctgg
gatgatgaagcctatgtgttcaacaaggtggtattacccaccctggcgtctcttcgatta
gcagtgtttgaggaaaatgggaagtttcttggtcatcgtatcttgccagtatcggctttg
cgcccaggatatcactacatcagtctgaagaatgaactgaaccaaccactcatgctggca
tccctgcttgtgtacactgaagctagggactacatccccaatgagcaccaagaatacgca
gaggctctgacaaacccaatcaaacatctctctctgctggcccagagagaaaagcagcta
ttagcacttatggaggatctccctgtggaagtcaaaaaagagatgctgcgaaaccaggat
aagacggagaaactagacgaaggagactctaactctggctgcgtaccttctgctgaccct
ttctgccctctgccatcatctccaacacttcctcctgtagtcagtgaggtcatgaactct
cctccatcaggcccaaaagaagatctagtcaacaatattcttaaagttatcgaacctcag
tctattgatgagctcaaacagcaaaactcctaccagaagctgaagaagaaacagtccaag
gaactcaaggagttgagcaagaaacatgtgaaaaagttgtgggctctcagtaaggaacaa
aagactcgatgtactcagctgaactctgacctccagaggaaacgaagtcagatggagaag
cgtttgcgcagcagtctgaagaaaaatgggtcagaggaacctgcgcagagggaattgaaa
gagctggatctggagctagagagacagacagagcagttcagagaggagcagctgcaggag
cttcttgcgctcagacaggcacaacatcagacagagaaagaggctaaacaatgccacctc
aaagaggcaaatcagaaactgagggaaatcgcccaagactgccaagcatcccagatcaaa
aaactcaaggaagtgtgtgacaaagagaagaaagagttacagaagattttggaaaggaag
aggctaaacagcatcattgaggccaagaaatctgaaaaggaaatcagggagctgaccgag
atcaatagaaaacatatcaatgaatcggtcagcttaatccgtcagctggaagtgtctcag
gggaaacgtcaagagaagttgaaagcccttcacaaggacatccttcagaaaattgaggag
gaggttccactggaccaggcccgtctgacactcgagtgcgaggcggaaatgacgctcttg
ccaggggaggtgtctcgcttcatgcaggaggtcgagagcaaaggctctcgtaaagacacc
ctgataggtcaggccaatgacagcctcagctctggcccctcctccaactgcagcacgccc
ccttacacctccccaaaccacacctgggggagcaacatgggcaatgctgtctcaatgctg
gaatcctcctcaacctcaaacactcccgtcaagtcagagacggacactacaggagtgtac
tag

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (7)   
   Pfam (7)   
All databases (13)   

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