KEGG   Pan paniscus (bonobo): 100967291
Entry
100967291         CDS       T02283                                 

Gene name
FGF19
Definition
(RefSeq) fibroblast growth factor 19
  KO
K22603  fibroblast growth factor 19
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04810  Regulation of actin cytoskeleton
pps05200  Pathways in cancer
pps05218  Melanoma
pps05224  Breast cancer
pps05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100967291 (FGF19)
   04014 Ras signaling pathway
    100967291 (FGF19)
   04015 Rap1 signaling pathway
    100967291 (FGF19)
   04020 Calcium signaling pathway
    100967291 (FGF19)
   04151 PI3K-Akt signaling pathway
    100967291 (FGF19)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100967291 (FGF19)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100967291 (FGF19)
  09162 Cancer: specific types
   05226 Gastric cancer
    100967291 (FGF19)
   05218 Melanoma
    100967291 (FGF19)
   05224 Breast cancer
    100967291 (FGF19)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100967291 (FGF19)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100967291 (FGF19)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100967291 (FGF19)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100967291 (FGF19)
SSDB
Motif
Pfam: FGF
Other DBs
NCBI-GeneID: 100967291
NCBI-ProteinID: XP_014202332
Position
11
AA seq 114 aa
MGADGKMQGLLQYSEEDCAFEEEIRPDGYNVYRSEKHRLPVSLSSAKQRQLYKNRGFLPL
SHFLPMLPMVPEEPEDLRGHLESDMFSSPLETDSMDPFGLVTGLEAVRSPSFEK
NT seq 345 nt   +upstreamnt  +downstreamnt
atgggcgccgacggcaagatgcaggggctgcttcagtactcggaggaagactgtgctttc
gaggaggagatccgcccagatggctacaatgtgtaccgatccgagaagcaccgcctcccg
gtctccctgagcagtgccaaacagcggcagctgtacaagaacagaggctttcttccactc
tctcatttcctgcccatgctgcccatggtcccagaggagcctgaggacctcaggggccac
ttggaatctgacatgttctcttcgcccctggagaccgacagcatggacccatttgggctt
gtcaccggactggaggccgtgaggagtcccagctttgagaagtaa

KEGG   Pan paniscus (bonobo): 100967638
Entry
100967638         CDS       T02283                                 

Gene name
FGF4
Definition
(RefSeq) fibroblast growth factor 4
  KO
K04358  fibroblast growth factor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04810  Regulation of actin cytoskeleton
pps05200  Pathways in cancer
pps05218  Melanoma
pps05224  Breast cancer
pps05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100967638 (FGF4)
   04014 Ras signaling pathway
    100967638 (FGF4)
   04015 Rap1 signaling pathway
    100967638 (FGF4)
   04020 Calcium signaling pathway
    100967638 (FGF4)
   04151 PI3K-Akt signaling pathway
    100967638 (FGF4)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100967638 (FGF4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100967638 (FGF4)
  09162 Cancer: specific types
   05226 Gastric cancer
    100967638 (FGF4)
   05218 Melanoma
    100967638 (FGF4)
   05224 Breast cancer
    100967638 (FGF4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100967638 (FGF4)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100967638 (FGF4)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100967638 (FGF4)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100967638 (FGF4)
SSDB
Motif
Pfam: FGF bpX1
Other DBs
NCBI-GeneID: 100967638
NCBI-ProteinID: XP_008952491
Position
11
AA seq 199 aa
MAPLQLRTFLAVNRSSAQLSSAAGPQGPSKGTKFPRPATSRERHSAPGAQENANGPPRER
KLGLRAPNSSAFARGHRARGAATGGPRHAPRPGPGWGTAGVGLASEGLLELSPVERGVVS
IFGVASRFFVAMSSKGKLYGSPFFTDECKFKEILLPNNYNAYESYKYPGMFIALSKNGKT
KKGNRVSPTMKVTHFLPRL
NT seq 600 nt   +upstreamnt  +downstreamnt
atggctcccctgcagctgcgaacattcctggcagtcaacaggagcagcgcgcagctgagc
tctgctgccggtcctcaaggccccagcaaaggaaccaagttcccgcggcctgcgaccagc
cgcgaacgccacagcgccccgggcgcccaggagaacgcgaacggccccccgcgggagcgg
aaactcgggctccgagcgcctaattccagcgccttcgcccgtgggcacagggcgcgcggt
gcagccacagggggcccgagacacgcgccccggcctggcccaggctggggaaccgctggg
gtcgggctcgcgtctgaaggcctgctggagctctcgcccgtggagcggggcgtggtgagc
atcttcggcgtggccagccggttcttcgtggccatgagcagcaagggcaagctctatggc
tcgcccttcttcaccgatgagtgcaagttcaaggagattctccttcccaacaactacaac
gcctacgagtcctacaagtaccccggcatgttcatcgccctgagcaagaatgggaagacc
aagaaggggaaccgagtgtcgcccaccatgaaggtcacccacttcctccccaggctgtga

KEGG   Pan paniscus (bonobo): 100967980
Entry
100967980         CDS       T02283                                 

Gene name
FGF3
Definition
(RefSeq) fibroblast growth factor 3
  KO
K04358  fibroblast growth factor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04810  Regulation of actin cytoskeleton
pps05200  Pathways in cancer
pps05218  Melanoma
pps05224  Breast cancer
pps05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100967980 (FGF3)
   04014 Ras signaling pathway
    100967980 (FGF3)
   04015 Rap1 signaling pathway
    100967980 (FGF3)
   04020 Calcium signaling pathway
    100967980 (FGF3)
   04151 PI3K-Akt signaling pathway
    100967980 (FGF3)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100967980 (FGF3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100967980 (FGF3)
  09162 Cancer: specific types
   05226 Gastric cancer
    100967980 (FGF3)
   05218 Melanoma
    100967980 (FGF3)
   05224 Breast cancer
    100967980 (FGF3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100967980 (FGF3)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100967980 (FGF3)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100967980 (FGF3)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100967980 (FGF3)
SSDB
Motif
Pfam: FGF
Other DBs
NCBI-GeneID: 100967980
NCBI-ProteinID: XP_003828865
Position
11
AA seq 141 aa
MNKRGRLYASEHYSAECEFVERIHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVN
GKGRPRRGFKTRRTQKSSLFLPRVLDHRDHEMVRQLQSGLPRPPGKGVQPRRRRQKQSPD
NLEPSHIQASRLGSQLEASAH
NT seq 426 nt   +upstreamnt  +downstreamnt
atgaacaagaggggacgactctatgcttcggagcactacagcgccgagtgcgagtttgtg
gagcggatccacgagctgggctataatacgtatgcctcccggctgtaccggacggtgtct
agtacgcctggggcccggcggcagcccagcgccgagagactgtggtacgtgtctgtgaac
ggcaagggccggccccgcaggggcttcaagacccgccgcacacagaagtcctccctgttc
ctgccccgcgtgctggaccacagggaccacgagatggtgcggcagctacagagtgggctg
cccagaccccctggtaagggggtccagccccgacggcggcggcagaagcagagcccggat
aacctggagccctctcacattcaggcttcgagactgggctcccagctggaggccagtgcg
cactag

KEGG   Pan paniscus (bonobo): 100968351
Entry
100968351         CDS       T02283                                 

Gene name
FGF2
Definition
(RefSeq) fibroblast growth factor 2
  KO
K18497  fibroblast growth factor 2
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01521  EGFR tyrosine kinase inhibitor resistance
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04550  Signaling pathways regulating pluripotency of stem cells
pps04810  Regulation of actin cytoskeleton
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05200  Pathways in cancer
pps05205  Proteoglycans in cancer
pps05218  Melanoma
pps05224  Breast cancer
pps05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100968351 (FGF2)
   04014 Ras signaling pathway
    100968351 (FGF2)
   04015 Rap1 signaling pathway
    100968351 (FGF2)
   04020 Calcium signaling pathway
    100968351 (FGF2)
   04151 PI3K-Akt signaling pathway
    100968351 (FGF2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100968351 (FGF2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100968351 (FGF2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100968351 (FGF2)
   05205 Proteoglycans in cancer
    100968351 (FGF2)
  09162 Cancer: specific types
   05226 Gastric cancer
    100968351 (FGF2)
   05218 Melanoma
    100968351 (FGF2)
   05224 Breast cancer
    100968351 (FGF2)
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    100968351 (FGF2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100968351 (FGF2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100968351 (FGF2)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100968351 (FGF2)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100968351 (FGF2)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100968351 (FGF2)
SSDB
Motif
Pfam: FGF Fascin IL1
Other DBs
NCBI-GeneID: 100968351
NCBI-ProteinID: XP_008967714
Position
4
AA seq 155 aa
MAAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHI
KLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKY
TSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
NT seq 468 nt   +upstreamnt  +downstreamnt
atggcagccgggagcatcaccacgctgcccgccttgcccgaggatggcggcagcggcgcc
ttcccgcccggccacttcaaggaccccaagcggctgtactgcaaaaacgggggcttcttc
ctgcgcatccaccccgacggccgagttgacggggtccgggagaagagcgaccctcacatc
aagctacaacttcaagcagaagagagaggagttgtgtctatcaaaggagtgtgtgctaac
cgttaccttgctatgaaggaagatggaagattactggcttctaaatgtgttacggatgag
tgtttcttttttgaacgattggaatctaataactacaatacttaccggtcaaggaaatac
accagttggtatgtggcactgaaacgaactgggcagtataaacttggatccaaaacagga
cctgggcagaaagctatactttttcttccaatgtctgctaagagctga

KEGG   Pan paniscus (bonobo): 100968963
Entry
100968963         CDS       T02283                                 

Gene name
FGF22
Definition
(RefSeq) fibroblast growth factor 22
  KO
K04358  fibroblast growth factor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04810  Regulation of actin cytoskeleton
pps05200  Pathways in cancer
pps05218  Melanoma
pps05224  Breast cancer
pps05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100968963 (FGF22)
   04014 Ras signaling pathway
    100968963 (FGF22)
   04015 Rap1 signaling pathway
    100968963 (FGF22)
   04020 Calcium signaling pathway
    100968963 (FGF22)
   04151 PI3K-Akt signaling pathway
    100968963 (FGF22)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100968963 (FGF22)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100968963 (FGF22)
  09162 Cancer: specific types
   05226 Gastric cancer
    100968963 (FGF22)
   05218 Melanoma
    100968963 (FGF22)
   05224 Breast cancer
    100968963 (FGF22)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100968963 (FGF22)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100968963 (FGF22)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100968963 (FGF22)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100968963 (FGF22)
SSDB
Motif
Pfam: FGF Fascin
Other DBs
NCBI-GeneID: 100968963
NCBI-ProteinID: XP_008973482
Position
19
AA seq 165 aa
WLGLAWLLLARAPDAAGTPSASRGPRSYPHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTR
WRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTVDCRFRERIEENGHN
TYASQRWRRRGQPMFLALDRRGGPRPGGRTRRYHLSAHFLPVLVS
NT seq 498 nt   +upstreamnt  +downstreamnt
tggctgggcctggcctggctgctgctggcgcgggcgcccgacgccgcgggaaccccgagc
gcgtcgcggggaccgcgcagctacccgcacctggagggcgacgtgcgctggcggcgcctc
ttctcctccactcacttcttcctgcgcgtggatcccggcggccgcgtgcagggcacccgc
tggcgccacggccaggacagcatcctggagatccgctctgtacacgtgggcgtcgtggtc
atcaaagcagtgtcctcaggcttctacgtggccatgaaccgccggggccgcctctacggg
tcgcgactctacaccgtggactgcaggttccgggagcgcatcgaagagaacggccacaac
acctacgcctcacagcgctggcgccgccgcggccagcccatgttcctggcgctggacagg
aggggggggccccggccaggcggccggacgcggcggtaccacctgtccgcccacttcctg
cccgtcctggtctcctga

KEGG   Pan paniscus (bonobo): 100969230
Entry
100969230         CDS       T02283                                 

Gene name
FGF8
Definition
(RefSeq) fibroblast growth factor 8
  KO
K04358  fibroblast growth factor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04810  Regulation of actin cytoskeleton
pps05200  Pathways in cancer
pps05218  Melanoma
pps05224  Breast cancer
pps05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100969230 (FGF8)
   04014 Ras signaling pathway
    100969230 (FGF8)
   04015 Rap1 signaling pathway
    100969230 (FGF8)
   04020 Calcium signaling pathway
    100969230 (FGF8)
   04151 PI3K-Akt signaling pathway
    100969230 (FGF8)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100969230 (FGF8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100969230 (FGF8)
  09162 Cancer: specific types
   05226 Gastric cancer
    100969230 (FGF8)
   05218 Melanoma
    100969230 (FGF8)
   05224 Breast cancer
    100969230 (FGF8)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100969230 (FGF8)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100969230 (FGF8)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100969230 (FGF8)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100969230 (FGF8)
SSDB
Motif
Pfam: FGF FRG1 Fascin
Other DBs
NCBI-GeneID: 100969230
NCBI-ProteinID: XP_014202015
Position
10
AA seq 140 aa
MAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLE
NNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLN
YPPFTRSLRGSQRTWAPEPR
NT seq 423 nt   +upstreamnt  +downstreamnt
atggcagaggacggcgaccccttcgcaaagctcatcgtggagacggacacctttggaagc
agagttcgagtccgaggagccgagacgggcctctacatctgcatgaacaagaaggggaag
ctgatcgccaagagcaacggcaaaggcaaggactgcgtcttcacggaaattgtgctggag
aacaactacacagcgctgcagaatgccaagtacgagggctggtacatggccttcacccgc
aagggccggccccgcaagggctccaagacgcggcagcaccagcgtgaggtccacttcatg
aagcggctgccccggggccaccacaccaccgagcagagcctgcgcttcgagttcctcaac
tacccgcccttcacgcgcagcctgcgcggcagccagaggacttgggcccccgagccccga
tag

KEGG   Pan paniscus (bonobo): 100969352
Entry
100969352         CDS       T02283                                 

Gene name
GDNF
Definition
(RefSeq) glial cell derived neurotrophic factor
  KO
K05452  glial cell derived neurotrophic factor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04020  Calcium signaling pathway
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    100969352 (GDNF)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100969352 (GDNF)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100969352 (GDNF)
SSDB
Motif
Pfam: TGF_beta
Other DBs
NCBI-GeneID: 100969352
NCBI-ProteinID: XP_003811003
UniProt: A0A2R8ZCZ4
Position
5
AA seq 228 aa
MQSLPNSNGAAAGRDFKMKLWDVVAVCLVLLHTASAFPLPAGKRPPEAPAEDRSLGRRRA
PFALSSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENS
RGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNL
SRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
NT seq 687 nt   +upstreamnt  +downstreamnt
atgcagtctttgcctaacagcaatggtgccgccgccggacgggactttaagatgaagtta
tgggatgtcgtggctgtctgcctggtgctgctccacaccgcgtccgccttcccgctgccc
gccggtaagaggcctcccgaggcgcccgccgaagaccgctccctcggccgccgccgcgcg
cccttcgcgctgagcagtgactcaaatatgccagaggattatcctgatcagttcgatgat
gtcatggattttattcaagccaccattaaaagactgaaaaggtcaccagataaacaaatg
gcagtgcttcctagaagagagcggaatcggcaggctgcagctgccaacccagagaattcc
agaggaaaaggtcggagaggccagaggggcaaaaaccggggttgtgtcttaactgcaata
catttaaatgtcactgacttgggtctgggctatgaaaccaaggaggaactgatttttagg
tactgcagcggctcttgcgatgcagctgagacaacgtacgacaaaatattgaaaaactta
tccagaaatagaaggctggtgagtgacaaagtagggcaggcatgttgcagacccatcgcc
tttgatgatgacctgtcgtttttagatgataacctggtttaccatattctaagaaagcat
tccgctaaaaggtgtggatgtatctga

KEGG   Pan paniscus (bonobo): 100969999
Entry
100969999         CDS       T02283                                 

Gene name
VEGFD, FIGF
Definition
(RefSeq) vascular endothelial growth factor D
  KO
K05449  vascular endothelial growth factor C/D
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04510  Focal adhesion
pps04668  TNF signaling pathway
pps04926  Relaxin signaling pathway
pps04933  AGE-RAGE signaling pathway in diabetic complications
pps05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100969999 (VEGFD)
   04014 Ras signaling pathway
    100969999 (VEGFD)
   04015 Rap1 signaling pathway
    100969999 (VEGFD)
   04668 TNF signaling pathway
    100969999 (VEGFD)
   04020 Calcium signaling pathway
    100969999 (VEGFD)
   04151 PI3K-Akt signaling pathway
    100969999 (VEGFD)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100969999 (VEGFD)
 09150 Organismal Systems
  09152 Endocrine system
   04926 Relaxin signaling pathway
    100969999 (VEGFD)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100969999 (VEGFD)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100969999 (VEGFD)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100969999 (VEGFD)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100969999 (VEGFD)
SSDB
Motif
Pfam: PDGF CXCXC
Other DBs
NCBI-GeneID: 100969999
NCBI-ProteinID: XP_003805765
UniProt: A0A2R9C7K7
Position
X
AA seq 354 aa
MYREWVVVNIFMMLYVQLVQGSSNEHGPVKRSSQSTLERSEQQIRAASSLEELLRITHSE
DWKLWRCRLRLKSFTSMDSRSASHRSTRFAATFYDIETLKVIDEEWQRTQCSPRETCVEV
ASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNTSTSYISKQLFEISVPLTSVPELVP
VKVANHTGCKCLPTAPRHPYSIIRRSIQIPEEDRCSHSKKLCPIDMLWDSNKCKCVLQEE
NPLAGTEDHSYLQEPALCGPHMMFDEDRCECVCKTPCPKDLIQHPKNCSCFECKESLETC
CQKHKLFHPDTCSCEDRCPFHTRPCASGKTACAKHCRFPKEKRAAQGPHSRKNP
NT seq 1065 nt   +upstreamnt  +downstreamnt
atgtacagagagtgggtagtggtgaatattttcatgatgttgtacgtccagctggtgcag
ggctccagtaatgaacatggaccagtgaagcgatcatctcagtccacattagaacgatct
gaacagcagatcagggctgcttctagtttggaggaactacttcgaattactcactctgag
gactggaagctgtggagatgcaggctgaggctcaaaagttttaccagtatggactctcgc
tcagcatcccatcggtccactaggtttgcggcaactttctatgacattgaaacactaaaa
gttatagatgaagaatggcaaagaactcagtgcagccctagagaaacgtgcgtggaggtg
gccagtgagctggggaagagtaccaacacattcttcaagcccccttgtgtgaacgtgttc
cgatgtggtggctgttgcaatgaagagagccttatctgtatgaacaccagcacctcgtac
atttccaaacagctctttgagatatcagtgcctttgacatcagtacctgaattagtgcct
gttaaagttgccaatcatacaggttgtaagtgcttgccaacagccccccgccatccatac
tcaattatcagaagatccatccagatccctgaagaagatcgttgttcccattccaagaaa
ctctgtcctattgacatgctatgggatagcaacaaatgtaaatgtgttttacaggaggaa
aatccacttgctggaacagaagaccactcttatctccaggaaccagctctctgtgggcca
cacatgatgtttgacgaagatcgttgcgagtgtgtctgtaaaacaccatgtcccaaagat
ctaatccagcaccccaaaaactgcagttgctttgagtgcaaagaaagtctggagacctgc
tgccagaagcacaagctatttcacccagacacctgcagctgtgaggacagatgccccttt
cataccagaccatgtgcaagtggcaaaacagcatgtgcaaagcattgccgctttccaaag
gagaaaagggctgcccaggggccccacagccgaaagaatccttga

KEGG   Pan paniscus (bonobo): 100970008
Entry
100970008         CDS       T02283                                 

Gene name
FGF20
Definition
(RefSeq) fibroblast growth factor 20
  KO
K04358  fibroblast growth factor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04810  Regulation of actin cytoskeleton
pps05200  Pathways in cancer
pps05218  Melanoma
pps05224  Breast cancer
pps05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100970008 (FGF20)
   04014 Ras signaling pathway
    100970008 (FGF20)
   04015 Rap1 signaling pathway
    100970008 (FGF20)
   04020 Calcium signaling pathway
    100970008 (FGF20)
   04151 PI3K-Akt signaling pathway
    100970008 (FGF20)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100970008 (FGF20)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100970008 (FGF20)
  09162 Cancer: specific types
   05226 Gastric cancer
    100970008 (FGF20)
   05218 Melanoma
    100970008 (FGF20)
   05224 Breast cancer
    100970008 (FGF20)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100970008 (FGF20)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100970008 (FGF20)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100970008 (FGF20)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100970008 (FGF20)
SSDB
Motif
Pfam: FGF
Other DBs
NCBI-GeneID: 100970008
NCBI-ProteinID: XP_003823708
UniProt: A0A2R9AHG1
Position
8
AA seq 212 aa
MAPLAEVGGFLGGLEGLGQQVGSHFLLPPAGERPPLLGERRSAAERSARGGPGAAQLAHL
HGILRRRQLYCRTGFHLQILPDGSVVQGTRQDHSLFGILEFISVAVGLVSIRGVDSGLYL
GMNDKGELYGSEKLTSECIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGA
RSKRHQKFTHFLPRPVDPERVPELYKDLLMYT
NT seq 639 nt   +upstreamnt  +downstreamnt
atggctcccttagccgaagtcgggggctttctgggcggcctggagggcttgggccagcag
gtgggttcgcatttcctgttgcctcctgccggggagcggccgccgctgctgggcgagcgc
aggagcgcggcggagcggagcgcccgcggcgggccgggggctgcgcagctggcgcacctg
cacggcatcctgcgccgccggcagctctattgccgcaccggcttccacctgcagatcctg
cccgacggcagcgtcgtgcagggcacccggcaggaccacagcctcttcggtatcttggaa
ttcatcagtgtggcagtgggactggtcagtattagaggtgtggacagtggtctctatctt
ggaatgaatgacaaaggagaactctatggatcagagaaacttacttccgaatgcatcttt
agggagcagtttgaagagaactggtataacacctattcatctaacatatataaacatgga
gacactggccgcaggtattttgtggcacttaacaaagacggaactccaagagatggcgcc
aggtccaagaggcatcagaaatttacacatttcttacctagaccagtggatccagaaaga
gttccagaattgtacaaggacctactgatgtacacttga

KEGG   Pan paniscus (bonobo): 100970217
Entry
100970217         CDS       T02283                                 

Gene name
VEGFA
Definition
(RefSeq) vascular endothelial growth factor A
  KO
K05448  vascular endothelial growth factor A
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01521  EGFR tyrosine kinase inhibitor resistance
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04066  HIF-1 signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04370  VEGF signaling pathway
pps04510  Focal adhesion
pps04926  Relaxin signaling pathway
pps04933  AGE-RAGE signaling pathway in diabetic complications
pps05163  Human cytomegalovirus infection
pps05165  Human papillomavirus infection
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05200  Pathways in cancer
pps05205  Proteoglycans in cancer
pps05206  MicroRNAs in cancer
pps05211  Renal cell carcinoma
pps05212  Pancreatic cancer
pps05219  Bladder cancer
pps05323  Rheumatoid arthritis
pps05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100970217 (VEGFA)
   04014 Ras signaling pathway
    100970217 (VEGFA)
   04015 Rap1 signaling pathway
    100970217 (VEGFA)
   04370 VEGF signaling pathway
    100970217 (VEGFA)
   04066 HIF-1 signaling pathway
    100970217 (VEGFA)
   04020 Calcium signaling pathway
    100970217 (VEGFA)
   04151 PI3K-Akt signaling pathway
    100970217 (VEGFA)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100970217 (VEGFA)
 09150 Organismal Systems
  09152 Endocrine system
   04926 Relaxin signaling pathway
    100970217 (VEGFA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100970217 (VEGFA)
   05206 MicroRNAs in cancer
    100970217 (VEGFA)
   05205 Proteoglycans in cancer
    100970217 (VEGFA)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    100970217 (VEGFA)
   05211 Renal cell carcinoma
    100970217 (VEGFA)
   05219 Bladder cancer
    100970217 (VEGFA)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    100970217 (VEGFA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100970217 (VEGFA)
   05165 Human papillomavirus infection
    100970217 (VEGFA)
  09163 Immune disease
   05323 Rheumatoid arthritis
    100970217 (VEGFA)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    100970217 (VEGFA)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100970217 (VEGFA)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100970217 (VEGFA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100970217 (VEGFA)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100970217 (VEGFA)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100970217 (VEGFA)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100970217 (VEGFA)
SSDB
Motif
Pfam: PDGF VEGF_C CXCXC
Other DBs
NCBI-GeneID: 100970217
NCBI-ProteinID: XP_008956987
UniProt: A0A2R8ZTA0
Position
6
AA seq 163 aa
MAEGGGQNHHEVVKFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCN
DEGLECVPTEESNITMQIMRIKPHQGQHIGEMSFLQHNKCECRPKKDRARQENPCGPCSE
RRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
NT seq 492 nt   +upstreamnt  +downstreamnt
atggcagaaggaggagggcagaatcatcacgaagtggtgaagttcatggatgtctatcag
cgcagctactgccatccaatcgagaccctggtggacatcttccaggagtaccctgatgag
atagagtacatcttcaagccatcctgtgtgcccctgatgcgatgcgggggctgctgcaat
gacgagggcctggagtgtgtgcccactgaggagtccaacatcaccatgcagattatgcgg
atcaaacctcaccaaggccagcacataggagagatgagcttcctacagcacaacaaatgt
gaatgcagaccaaagaaagatagagcaagacaagaaaatccctgtgggccttgctcagag
cggagaaagcatttgtttgtacaagatccgcagacgtgtaaatgttcctgcaaaaacaca
gactcgcgttgcaaggcgaggcagcttgagttaaacgaacgtacttgcagatgtgacaag
ccgaggcggtga

KEGG   Pan paniscus (bonobo): 100972676
Entry
100972676         CDS       T02283                                 

Gene name
FGF1
Definition
(RefSeq) fibroblast growth factor 1
  KO
K18496  fibroblast growth factor 1
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04390  Hippo signaling pathway
pps04810  Regulation of actin cytoskeleton
pps05200  Pathways in cancer
pps05218  Melanoma
pps05224  Breast cancer
pps05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100972676 (FGF1)
   04014 Ras signaling pathway
    100972676 (FGF1)
   04015 Rap1 signaling pathway
    100972676 (FGF1)
   04390 Hippo signaling pathway
    100972676 (FGF1)
   04020 Calcium signaling pathway
    100972676 (FGF1)
   04151 PI3K-Akt signaling pathway
    100972676 (FGF1)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100972676 (FGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100972676 (FGF1)
  09162 Cancer: specific types
   05226 Gastric cancer
    100972676 (FGF1)
   05218 Melanoma
    100972676 (FGF1)
   05224 Breast cancer
    100972676 (FGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100972676 (FGF1)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100972676 (FGF1)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100972676 (FGF1)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100972676 (FGF1)
SSDB
Motif
Pfam: FGF Fascin Methyltrans_RNA
Other DBs
NCBI-GeneID: 100972676
NCBI-ProteinID: XP_003829149
Position
5
AA seq 214 aa
MHHAATLSPFLQCPPDTGPESGLEGAGISHLLKCWMQPLSFGRSRKLRLESATSSSCXAM
AEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQL
SAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKN
WFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD
NT seq 645 nt   +upstreamnt  +downstreamnt
atgcaccatgccgccacattatctccattcctccagtgcccgcctgacactggccctgaa
tcagggctggagggggcaggcatttctcatttactaaagtgctggatgcagcccttgagt
ttcggcagaagcagaaagctgcgtcttgaaagcgccacaagcagcagctgctgagccatg
gctgaaggggaaatcaccaccttcacagccctgaccgagaagtttaatctgcctccaggg
aattacaagaagcccaaactcctctactgtagcaacgggggccacttcctgaggatcctt
ccggatggcacagtggatgggacaagggacaggagcgaccagcacattcagctgcagctc
agtgcggaaagcgtgggggaggtgtatataaagagtaccgagactggccagtacttggcc
atggacaccgacgggcttttatacggctcacagacaccaaatgaggaatgtttgttcctg
gaacggctggaggagaaccattacaacacctatatatccaagaagcatgcagagaagaat
tggtttgttggcctcaagaagaatggaagctgcaaacgcggtcctcggactcactatggc
cagaaagcaatcttgtttctccccctgccagtctcttccgattaa

KEGG   Pan paniscus (bonobo): 100975521
Entry
100975521         CDS       T02283                                 

Gene name
FGF21
Definition
(RefSeq) fibroblast growth factor 21
  KO
K22429  fibroblast growth factor 21
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04714  Thermogenesis
pps04810  Regulation of actin cytoskeleton
pps05200  Pathways in cancer
pps05218  Melanoma
pps05224  Breast cancer
pps05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100975521 (FGF21)
   04014 Ras signaling pathway
    100975521 (FGF21)
   04015 Rap1 signaling pathway
    100975521 (FGF21)
   04020 Calcium signaling pathway
    100975521 (FGF21)
   04151 PI3K-Akt signaling pathway
    100975521 (FGF21)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100975521 (FGF21)
 09150 Organismal Systems
  09159 Environmental adaptation
   04714 Thermogenesis
    100975521 (FGF21)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100975521 (FGF21)
  09162 Cancer: specific types
   05226 Gastric cancer
    100975521 (FGF21)
   05218 Melanoma
    100975521 (FGF21)
   05224 Breast cancer
    100975521 (FGF21)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100975521 (FGF21)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100975521 (FGF21)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100975521 (FGF21)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100975521 (FGF21)
SSDB
Motif
Pfam: FGF
Other DBs
NCBI-GeneID: 100975521
NCBI-ProteinID: XP_003814163
UniProt: A0A2R9AZE4
Position
19
AA seq 147 aa
MDSDETGFEHSGLWVSVLAGLLLGACQAHPIPDSSPLLQFGGQVRQRYLYTDDAQQTEAH
LEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSVSFQDPP
HHPPCSSYMSPSQPGVPCLAHPPRSQT
NT seq 444 nt   +upstreamnt  +downstreamnt
atggactcggacgagaccgggttcgagcactcaggactgtgggtttctgtgctggctggt
cttctgctgggagcctgccaggcacaccccatccctgactccagtcctctcctgcaattc
gggggccaagtccggcagcggtacctctacacagatgatgcccagcagacagaagcccac
ctggagatcagggaggatgggacggtggggggcgctgctgaccagagccccgaaagtctc
ctgcagctgaaagccttgaagccgggagttattcaaatcttgggagtcaagacatccagg
ttcctgtgccagaggccagatggggccctgtatggatcggtgagtttccaggaccctcct
caccacccaccatgctcctcctatatgtcgccctcacagcctggggtgccgtgtcttgct
catcccccccggagccagacttga

KEGG   Pan paniscus (bonobo): 100975632
Entry
100975632         CDS       T02283                                 

Gene name
EGF
Definition
(RefSeq) epidermal growth factor
  KO
K04357  epidermal growth factor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01521  EGFR tyrosine kinase inhibitor resistance
pps04010  MAPK signaling pathway
pps04012  ErbB signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04066  HIF-1 signaling pathway
pps04068  FoxO signaling pathway
pps04072  Phospholipase D signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04510  Focal adhesion
pps04540  Gap junction
pps04630  JAK-STAT signaling pathway
pps04810  Regulation of actin cytoskeleton
pps05160  Hepatitis C
pps05165  Human papillomavirus infection
pps05200  Pathways in cancer
pps05210  Colorectal cancer
pps05212  Pancreatic cancer
pps05213  Endometrial cancer
pps05214  Glioma
pps05215  Prostate cancer
pps05218  Melanoma
pps05219  Bladder cancer
pps05223  Non-small cell lung cancer
pps05224  Breast cancer
pps05226  Gastric cancer
pps05231  Choline metabolism in cancer
pps05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100975632 (EGF)
   04012 ErbB signaling pathway
    100975632 (EGF)
   04014 Ras signaling pathway
    100975632 (EGF)
   04015 Rap1 signaling pathway
    100975632 (EGF)
   04630 JAK-STAT signaling pathway
    100975632 (EGF)
   04066 HIF-1 signaling pathway
    100975632 (EGF)
   04068 FoxO signaling pathway
    100975632 (EGF)
   04020 Calcium signaling pathway
    100975632 (EGF)
   04072 Phospholipase D signaling pathway
    100975632 (EGF)
   04151 PI3K-Akt signaling pathway
    100975632 (EGF)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100975632 (EGF)
   04540 Gap junction
    100975632 (EGF)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100975632 (EGF)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100975632 (EGF)
   05231 Choline metabolism in cancer
    100975632 (EGF)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100975632 (EGF)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100975632 (EGF)
   05212 Pancreatic cancer
    100975632 (EGF)
   05226 Gastric cancer
    100975632 (EGF)
   05214 Glioma
    100975632 (EGF)
   05218 Melanoma
    100975632 (EGF)
   05219 Bladder cancer
    100975632 (EGF)
   05215 Prostate cancer
    100975632 (EGF)
   05213 Endometrial cancer
    100975632 (EGF)
   05224 Breast cancer
    100975632 (EGF)
   05223 Non-small cell lung cancer
    100975632 (EGF)
  09172 Infectious disease: viral
   05160 Hepatitis C
    100975632 (EGF)
   05165 Human papillomavirus infection
    100975632 (EGF)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100975632 (EGF)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100975632 (EGF)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100975632 (EGF)
SSDB
Motif
Pfam: Ldl_recept_b FXa_inhibition EGF cEGF EGF_CA EGF_3 DUF5050
Other DBs
NCBI-GeneID: 100975632
NCBI-ProteinID: XP_003830069
UniProt: A0A2R8Z6N6
Position
4
AA seq 1207 aa
MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVGPAPFLIFSHGNSIFRID
TEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVCNIEKNVSG
MAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFIFWSSEVAG
SLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCDYDGGSVHI
SKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPLGELKVVHP
LAQPKAEDDTWEPEQKLRKLRKGNCSSTVCGQDLQSHLCTCAEGYALSRDRKYCEDVNEC
AFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPSNVSECSHDCVLTSEGPL
CFCPEGSVLERDGKTCSGCSSPDNGGCSQLCIPLSPVSWECDCFPGYDLQLDKKSCAASG
PQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTALKWIERAN
MDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKIIAKENLSQP
RGIAIHPMAKRLFWTDTGINPRIESSSLQGLGRLIIASSDLIWPSGITIDFLTDKLYWCD
AKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVIRVNKRTGKDRVR
LQGSMLKPSSLVVVHPLVKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTC
LALDGHQLLAGGEVDLKNQVTPLDILSQTRVSEDNITESQHMLVAEIMVSDQDDCAPVGC
STYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCS
EGYQGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAGRLSEPGLICPDSTPPPHL
REDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWW
ELRHAGHGQQQKVIVVAVCVVVLVVLLLLSLWGAHYYRTQKLLSKNPKNPYEESSRDVRS
RRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGSMQPTSWRQEPRLCGM
GTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLWQQRALDPP
HQMELTQ
NT seq 3624 nt   +upstreamnt  +downstreamnt
atgctgctcactcttatcattctgttgccagtagtttcaaaatttagttttgttagtctc
tcagcaccgcagcactggagctgtcctgaaggtactcttgcaggaaatgggaattctact
tgtgtgggtcctgcacccttcttaattttctcccacggaaatagtatctttaggattgac
acagaaggaaccaattatgagcaattggtggtggatgctggtgtctcagtgatcatggat
tttcattataatgagaaaagaatctattgggtggatttagaaagacaacttttgcaaaga
gtttttctgaatgggtcaaggcaagagagagtatgtaatatagagaaaaatgtttctgga
atggcaataaattggataaatgaagaagttatttggtcaaatcaacaggaaggaatcatt
acagtaacagatatgaaaggaaataattcccacattcttttaagtgctttaaaatatcct
gcaaatgtagcagttgatccagtagaaaggtttatattttggtcttcagaggtggctgga
agcctttatagagcagatctcgatggtgtgggagtgaaggctctgttggagacatcagag
aaaataacagctgtgtcattggatgtgcttgataagcggctgttttggattcagtacaac
agagaaggaagcaattctcttatttgctcctgtgattatgatggaggttctgtccacatt
agtaaacatccaacacagcataatttgtttgcaatgtccctttttggtgaccgtatcttc
tattcaacatggaaaatgaagacaatttggatagccaacaaacacactggaaaggacatg
gttagaattaacctccattcatcatttgtaccacttggtgaactgaaagtagtgcatcca
cttgcacaacccaaggcagaagatgacacttgggagcctgagcagaaacttcgcaaattg
aggaaaggaaactgcagcagcactgtgtgtgggcaagacctccagtcacacttgtgcacg
tgtgcagagggatacgccctaagtcgagaccggaagtactgtgaagatgttaatgaatgc
gctttttggaatcatggctgtactcttgggtgtaaaaacacccctggatcctattactgc
acatgccctgtaggatttgttctgcttcctgatgggaaacgatgtcatcaacttgtttcc
tgtccaagcaatgtgtctgaatgcagccatgactgtgttctgacatcagaaggtccctta
tgtttctgtcctgaaggctcggtgcttgagagagatgggaaaacatgtagcggttgttcc
tcacctgataatggtggatgtagccagctctgcattcctcttagcccagtatcctgggaa
tgtgattgctttcctgggtatgacctacaactggataaaaaaagctgtgcagcttcagga
ccacaaccatttttgctgtttgccaattctcaagatattcgacacatgcattttgatgga
acagactatggaactctgctcagccagcagatgggaatggtttatgccctagatcatgac
cctgtggaaaataagatatactttgcccatacagccctgaagtggatagagagagctaat
atggatggttcccagcgagaaaggcttattgaggaaggagtagatgtgccagaaggtctt
gctgtggactggattggccgtagattctattggacagacagagggaaatctctgattgga
aggagtgacttaaatgggaaacgttccaaaataatcgctaaggagaacctctctcaacca
cgaggaattgctattcatccaatggccaagagattattctggactgatacagggattaat
ccacgaattgaaagttcttccctccaaggccttggccgactgattatagccagctctgat
ctaatctggcccagtggaataacgattgacttcttaactgacaagttgtattggtgcgat
gccaagcagtctgtgattgaaatggccaatctggatggttcaaaacgccgaagacttacc
cagaatgatgtaggtcacccatttgctgtagcagtgtttgaggattatgtgtggttctca
gattgggctatgccatcagtaataagagtaaacaagaggactggcaaagatagagtacgt
ctccaaggcagcatgctgaagccctcatcactggttgtggttcatccattggtaaaacca
ggagcagatccctgcttatatcaaaatggaggctgtgaacatatttgcaaaaagaggctt
ggaactgcttggtgttcgtgtcgtgaaggttttatgaaagcctcagatgggaaaacgtgt
ctggctctggatggtcatcagctgttggcaggtggtgaagttgatctaaagaaccaagta
acaccattggacatcttgtcccagactagagtgtcagaagataacattacagaatctcaa
cacatgctagtggctgaaatcatggtgtcagatcaagatgactgtgctcctgtgggatgc
agcacgtatgctcggtgtatttcagagggagaggatgccacatgtcagtgtttgaaagga
tttgctggggatggaaaactatgttctgatatagatgaatgtgagatgggtgtcccagtg
tgcccccctgcctcctccaagtgcatcaacaccgaaggtggttatgtctgccggtgctca
gaaggctaccaaggagatgggattcactgtctcgatattgatgagtgccaactgggggtg
cacagctgtggagagaatgccagctgcacaaatacagagggaggctatacctgcatgtgt
gctggacgcctgtctgaaccaggactgatttgccctgactctactccaccccctcacctc
agggaagatgaccaccactattccgtaagaaatagtgactctgaatgtcccctgtcccac
gatgggtactgcctccatgatggtgtgtgcatgtatattgaagcattggacaagtatgca
tgcaactgtgttgttggctacatcggggagcgatgtcagtaccgagacctgaagtggtgg
gaactgcgccacgctggccacgggcagcagcagaaggtcatcgtggtggctgtctgcgtg
gtggtgcttgtcgtgctgctcctcctgagcctgtggggggcccactactacaggactcag
aagctgctatcgaaaaacccaaagaatccttatgaggagtcgagcagagacgtgaggagt
cgcaggcctgctgacactgaggatgggatgtcctcttgccctcaaccttggtttgtggtt
ataaaagaacaccaagacctcaagaatgggggtcaaccagtggctggtgaggatggccag
gcagcagatgggtcaatgcaaccaacttcatggaggcaggagccccggttatgtggaatg
ggcacagagcaaggctgctggattccagtatccagtgataagggctcctgtccccaggta
atggagcgaagctttcatatgccctcttatgggacacagacccttgaagggggtgtcgag
aagccccattctctcctatcagctaacccattatggcaacaaagggccctggacccacca
catcaaatggagctgactcagtga

KEGG   Pan paniscus (bonobo): 100979704
Entry
100979704         CDS       T02283                                 

Gene name
FGF9
Definition
(RefSeq) fibroblast growth factor 9
  KO
K04358  fibroblast growth factor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04810  Regulation of actin cytoskeleton
pps05200  Pathways in cancer
pps05218  Melanoma
pps05224  Breast cancer
pps05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100979704 (FGF9)
   04014 Ras signaling pathway
    100979704 (FGF9)
   04015 Rap1 signaling pathway
    100979704 (FGF9)
   04020 Calcium signaling pathway
    100979704 (FGF9)
   04151 PI3K-Akt signaling pathway
    100979704 (FGF9)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100979704 (FGF9)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100979704 (FGF9)
  09162 Cancer: specific types
   05226 Gastric cancer
    100979704 (FGF9)
   05218 Melanoma
    100979704 (FGF9)
   05224 Breast cancer
    100979704 (FGF9)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100979704 (FGF9)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100979704 (FGF9)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100979704 (FGF9)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100979704 (FGF9)
SSDB
Motif
Pfam: FGF
Other DBs
NCBI-GeneID: 100979704
NCBI-ProteinID: XP_003833080
UniProt: A0A2R8ZBT9
Position
13
AA seq 208 aa
MAPLGEVGNYFGVQDAVPFGNVPVLPVDSPVLLSDHLGQSEAGGLPRGPAVTDLDHLKGI
LRRRQLYCRTGFHLEIFPNGTIQGTRKDHSRFGILEFISIAVGLVSIRGVDSGLYLGMNE
KGELYGSEKLTQECVFREQFEENWYNTYSSNLYKHVDTGRRYYVALNKDGTPREGTRTKR
HQKFTHFLPRPVDPDKVPELYKDILSQS
NT seq 627 nt   +upstreamnt  +downstreamnt
atggctcccttaggtgaagttgggaactatttcggtgtgcaggatgcggtaccatttggg
aatgtgcccgtgttgccggtggacagcccggttttgttaagtgaccacctgggtcagtcc
gaagcaggggggctccccaggggacccgcagtcacggacttggatcatttaaaggggatt
ctcaggcggaggcagctatactgcaggactggatttcacttagaaatcttccccaatggt
actatccagggaaccaggaaagaccacagccgatttggcattctggaatttatcagtata
gcagtgggcctggtcagcattcgaggcgtggacagtggactctacctcgggatgaatgag
aagggggagctgtatggatcagaaaaactaacccaagagtgtgtattcagagaacagttc
gaagaaaactggtataatacgtactcatcaaacctatataagcacgtggacactggaagg
cgatactatgttgcattaaataaagatgggaccccgagagaagggactaggactaaacgg
caccagaaattcacacattttttacctagaccagtggaccccgacaaagtacctgaactg
tataaggatattctaagccaaagttga

KEGG   Pan paniscus (bonobo): 100980043
Entry
100980043         CDS       T02283                                 

Gene name
FGF5
Definition
(RefSeq) fibroblast growth factor 5
  KO
K04358  fibroblast growth factor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04810  Regulation of actin cytoskeleton
pps05200  Pathways in cancer
pps05218  Melanoma
pps05224  Breast cancer
pps05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100980043 (FGF5)
   04014 Ras signaling pathway
    100980043 (FGF5)
   04015 Rap1 signaling pathway
    100980043 (FGF5)
   04020 Calcium signaling pathway
    100980043 (FGF5)
   04151 PI3K-Akt signaling pathway
    100980043 (FGF5)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100980043 (FGF5)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100980043 (FGF5)
  09162 Cancer: specific types
   05226 Gastric cancer
    100980043 (FGF5)
   05218 Melanoma
    100980043 (FGF5)
   05224 Breast cancer
    100980043 (FGF5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100980043 (FGF5)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100980043 (FGF5)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100980043 (FGF5)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100980043 (FGF5)
SSDB
Motif
Pfam: FGF
Other DBs
NCBI-GeneID: 100980043
NCBI-ProteinID: XP_003832321
UniProt: A0A2R9AH42
Position
4
AA seq 268 aa
MSLSFLLFLFFSHLILSAWAHGEKRLAPKGQPGPAATDRNPRGSSSRQSSSSAMSSSSAS
SSPAASLGSQGSGLEQSSFQWSPSGRRTGSLYCRVGIGFHLQIYPDGKVNGSHEANMLSV
LEIFAVSQGIVGIRGVFSNKFLAMSKKGKLHASAKFTDDCKFRERFQENSYNTYASAIHR
TEKTGREWYVALNKRGKAKRGCSPRVKPQHISTHFLPRFKQSEQPELSFTVTVPEKKKPP
SPIKPKIPLSAPRKNTNSVKYRLKFRFG
NT seq 807 nt   +upstreamnt  +downstreamnt
atgagcttgtccttcctcctcttcctcttcttcagccacctgatcctcagcgcctgggct
cacggggagaagcgtctcgcccccaaagggcaacccggacccgctgccactgataggaac
cctagaggctccagcagcagacagagcagcagtagcgctatgtcttcctcttctgcctcc
tcctcccccgcagcttctctgggcagccaaggaagtggcttggagcagagcagtttccag
tggagcccctcggggcgtcggaccggcagcctctactgcagagtgggcatcggtttccat
ctgcagatctacccggacggcaaagtcaatggatcccacgaagccaatatgttaagtgtt
ttggaaatatttgctgtgtctcaggggattgtaggaatacgaggagttttcagcaacaaa
tttttagcgatgtcaaaaaaaggaaaactccatgcaagtgccaagttcacagatgactgc
aagttcagggagcgttttcaagaaaatagctataatacctatgcctcagcaatacataga
actgaaaaaacagggcgggagtggtatgtggccctgaataaaagaggaaaagccaaacga
gggtgcagcccccgggttaaaccccagcatatctctacccattttctgccaagattcaag
cagtcggagcagccagaactttctttcacggttactgttcctgaaaagaaaaagccacct
agccctatcaagccaaagattcccctttctgcacctcggaaaaataccaactcagtgaaa
tacagactcaagtttcgctttggataa

KEGG   Pan paniscus (bonobo): 100982459
Entry
100982459         CDS       T02283                                 

Gene name
PDGFC
Definition
(RefSeq) platelet derived growth factor C
  KO
K05450  platelet derived growth factor C/D
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01521  EGFR tyrosine kinase inhibitor resistance
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04072  Phospholipase D signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04510  Focal adhesion
pps04540  Gap junction
pps04810  Regulation of actin cytoskeleton
pps05215  Prostate cancer
pps05218  Melanoma
pps05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100982459 (PDGFC)
   04014 Ras signaling pathway
    100982459 (PDGFC)
   04015 Rap1 signaling pathway
    100982459 (PDGFC)
   04020 Calcium signaling pathway
    100982459 (PDGFC)
   04072 Phospholipase D signaling pathway
    100982459 (PDGFC)
   04151 PI3K-Akt signaling pathway
    100982459 (PDGFC)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100982459 (PDGFC)
   04540 Gap junction
    100982459 (PDGFC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100982459 (PDGFC)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    100982459 (PDGFC)
  09162 Cancer: specific types
   05218 Melanoma
    100982459 (PDGFC)
   05215 Prostate cancer
    100982459 (PDGFC)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100982459 (PDGFC)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100982459 (PDGFC)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100982459 (PDGFC)
SSDB
Motif
Pfam: CUB PDGF
Other DBs
NCBI-GeneID: 100982459
NCBI-ProteinID: XP_003822606
UniProt: A0A2R9BRW3
Position
4
AA seq 345 aa
MSLFGLLLLTSALAGQRQGTQAESNLSSKFQFSSNKEQNGVQDPQHERIITVSTNGSIHS
PRFPHTYPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPSDGTIL
GRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVMPQFTEAVSPSVLPPSA
LPLDLLNNAITAFSTLEDLIRYLEPERWQLDLEDLYKPTWQLLGKAFVFGRKSRVVDLNL
LTEEVRLYSCTPRNFSVSIREELKRTDTIFWPGCLLVKRCGGNCACCLHNCNECQCVPSK
VTKKYHEVLQLRPKTGVRGLHKSLTDVALEHHEECDCVCRGSTGG
NT seq 1038 nt   +upstreamnt  +downstreamnt
atgagcctcttcgggcttctcctgctgacatctgccctggccggccagagacaggggact
caggcggaatccaacctgagtagtaaattccagttttccagcaacaaggaacagaacgga
gtacaagatcctcagcatgagagaattattactgtgtctactaatggaagtattcacagc
ccaaggtttcctcatacttatccaagaaatacggtcttggtatggagattagtagcagta
gaggaaaatgtatggatacaacttacgtttgatgaaagatttgggcttgaagacccagaa
gatgacatatgcaagtatgattttgtagaagttgaggaacccagtgatggaactatatta
gggcgctggtgtggttctggtactgtaccaggaaaacagatttctaaaggaaatcaaatt
aggataagatttgtatctgatgaatattttccttctgaaccagggttctgcatccactac
aacattgtcatgccacaattcacagaagctgtgagtccttcagtgctacccccttcagct
ttgccactggacctgcttaataatgctataactgcctttagtaccttggaagaccttatt
cgatatcttgaaccagagagatggcagttggacttagaagatctatataagccaacttgg
caacttcttggcaaggcttttgtttttggaagaaaatccagagtggtggatctgaacctt
ctaacagaggaggtaagattatacagctgcacacctcgtaacttctcagtgtccataagg
gaagaactaaagagaaccgataccattttctggccaggttgtctcctggttaaacgctgt
ggtgggaactgtgcctgttgtctccacaattgcaacgaatgtcaatgtgttccaagcaaa
gttactaaaaaataccacgaggtccttcagttgagaccaaagaccggtgtcaggggattg
cacaaatcactcaccgacgtggccctggagcaccatgaggagtgtgactgtgtgtgcaga
gggagcacaggaggatag

KEGG   Pan paniscus (bonobo): 100982572
Entry
100982572         CDS       T02283                                 

Gene name
FGF17
Definition
(RefSeq) fibroblast growth factor 17
  KO
K04358  fibroblast growth factor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04810  Regulation of actin cytoskeleton
pps05200  Pathways in cancer
pps05218  Melanoma
pps05224  Breast cancer
pps05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100982572 (FGF17)
   04014 Ras signaling pathway
    100982572 (FGF17)
   04015 Rap1 signaling pathway
    100982572 (FGF17)
   04020 Calcium signaling pathway
    100982572 (FGF17)
   04151 PI3K-Akt signaling pathway
    100982572 (FGF17)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100982572 (FGF17)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100982572 (FGF17)
  09162 Cancer: specific types
   05226 Gastric cancer
    100982572 (FGF17)
   05218 Melanoma
    100982572 (FGF17)
   05224 Breast cancer
    100982572 (FGF17)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100982572 (FGF17)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100982572 (FGF17)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100982572 (FGF17)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100982572 (FGF17)
SSDB
Motif
Pfam: FGF Fascin IL1
Other DBs
NCBI-GeneID: 100982572
NCBI-ProteinID: XP_003823663
Position
8
AA seq 216 aa
MGAARLLPNLTLCLQLLILCCQTQGENHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSR
TSGKHVQVTGRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGKLIGKP
SGKSKDCVFTEIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKRLYQ
GQLPFPNHAEKQKQFEFVGSAPTRRTKRTRRPQPLT
NT seq 651 nt   +upstreamnt  +downstreamnt
atgggagccgcccgcctgctgcccaacctcactctgtgcttacagctgctgattctctgc
tgtcaaactcagggggagaatcacccgtctcctaattttaaccagtacgtgagggaccag
ggcgccatgactgaccagctgagcaggcggcagatccgcgagtaccaactctacagcagg
accagtggcaagcacgtgcaggtcaccgggcgtcgcatctccgccaccgccgaggacggc
aacaaatttgccaagctcatagtggagacggacacgtttggcagccgggttcgcatcaaa
ggggctgagagtgagaagtacatctgtatgaacaagaggggcaagctcatcgggaagccc
agcgggaaaagcaaagactgcgtgttcacggagatcgtgctggagaacaactacacggcc
ttccagaacgcccggcacgagggctggttcatggccttcacgcggcaggggcggccccgc
caggcttcccgcagccgccagaaccagcgtgaggcccacttcatcaagcgcctctaccaa
ggccagctgcccttccccaaccacgccgagaagcagaagcagttcgagtttgtgggctcc
gcccccacccgccggaccaagcgcacacggcggccccagcccctcacgtag

KEGG   Pan paniscus (bonobo): 100983117
Entry
100983117         CDS       T02283                                 

Gene name
HGF
Definition
(RefSeq) hepatocyte growth factor
  KO
K05460  hepatocyte growth factor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01521  EGFR tyrosine kinase inhibitor resistance
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04510  Focal adhesion
pps05144  Malaria
pps05200  Pathways in cancer
pps05205  Proteoglycans in cancer
pps05211  Renal cell carcinoma
pps05218  Melanoma
pps05223  Non-small cell lung cancer
pps05225  Hepatocellular carcinoma
pps05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100983117 (HGF)
   04014 Ras signaling pathway
    100983117 (HGF)
   04015 Rap1 signaling pathway
    100983117 (HGF)
   04020 Calcium signaling pathway
    100983117 (HGF)
   04151 PI3K-Akt signaling pathway
    100983117 (HGF)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100983117 (HGF)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100983117 (HGF)
   05205 Proteoglycans in cancer
    100983117 (HGF)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100983117 (HGF)
   05226 Gastric cancer
    100983117 (HGF)
   05218 Melanoma
    100983117 (HGF)
   05211 Renal cell carcinoma
    100983117 (HGF)
   05223 Non-small cell lung cancer
    100983117 (HGF)
  09174 Infectious disease: parasitic
   05144 Malaria
    100983117 (HGF)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100983117 (HGF)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100983117 (HGF)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100983117 (HGF)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100983117 (HGF)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100983117 (HGF)
SSDB
Motif
Pfam: Kringle Trypsin PAN_1 DUF1986 Trypsin_2
Other DBs
NCBI-GeneID: 100983117
NCBI-ProteinID: XP_003822790
Position
7
AA seq 728 aa
MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTP
HRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTDVPL
ETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGS
ESPWCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNME
DLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNL
DHPVISCAKTKQLRVVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRD
LKDYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLP
NYGCTIPEKTSCTVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAG
AEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII
LTYKVPQS
NT seq 2187 nt   +upstreamnt  +downstreamnt
atgtgggtgaccaaactcctgccagccctgctgctgcagcatgtcctcctgcatctcctc
ctgctccccatcgccatcccctatgcagagggacaaaggaaaagaagaaatacaattcat
gaattcaaaaaatcagcaaagactaccctaatcaaaatagatccagcactgaagataaaa
accaaaaaagtgaatactgcagaccaatgtgctaatagatgtactaggaataaaggactt
ccattcacttgcaaggcttttgtttttgataaagcaagaaaacaatgcctctggttcccc
ttcaatagcatgtcaagtggagtgaaaaaagagtttggccatgaatttgacctctatgaa
aacaaagactacattagaaactgcatcattggtaaaggacgcagctacaagggaacagta
tctatcactaagagtggcatcaaatgtcagccctggagttccatgataccacacgaacac
agctttttgccttcgagctatcggggtaaagacctacaggaaaactactgtcgaaatcct
cgaggggaagaagggggaccctggtgtttcacaagcaatccagaggtacgctacgaagtc
tgtgacattcctcagtgttcagaagttgaatgcatgacctgcaatggggagagttatcga
ggtctcatggatcatacagaatcaggcaagatttgtcagcgctgggatcatcagacacca
caccggcacaaattcttgcctgaaagatatcccgacaagggctttgatgataattattgc
cgcaatcccgatggccagccgaggccatggtgctatactcttgaccctcacacccgctgg
gagtactgtgcaattaaaacatgcgctgacaatactatgaatgacactgatgttcctttg
gaaacaactgaatgcatccaaggtcaaggagaaggctacaggggcactgtcaataccatt
tggaatggaattccatgtcagcgttgggattctcagtatcctcacgagcatgacatgact
cctgaaaatttcaagtgcaaggacctacgagaaaattactgccgaaatccagatgggtct
gaatcaccctggtgttttaccactgatccaaacatccgagttggctactgctcccaaatt
ccaaactgtgatatgtcacatggacaagattgttatcgtgggaatggcaaaaattatatg
ggcaacttatcccaaacaagatctggactaacatgttcaatgtgggacaagaacatggaa
gacttacatcgtcatatcttctgggaaccagatgcaagtaagctgaatgagaattactgc
cgaaatccagatgatgatgctcatggaccctggtgctacacgggaaatccactcattcct
tgggattattgccctatttctcgttgtgaaggtgataccacacctacaatagtcaattta
gaccatcccgtaatatcttgtgccaaaacgaaacaattgcgagttgtaaatgggattcca
acacgaacaaacataggatggatggttagtttgagatacagaaataaacatatctgcgga
ggatcattgataaaggagagttgggttcttactgcacgacagtgtttcccttctcgagac
ttgaaagattatgaagcttggcttggaattcatgatgtccacggaagaggagatgagaaa
tgcaaacaggttctcaatgtttcccagctggtatatggccctgaaggatcagatctggtt
ttaatgaagcttgccaggcctgctgtcctggatgattttgttagtacgattgatttacct
aattatggatgcacaattcctgaaaagaccagttgcactgtttatggctggggctacact
ggattgatcaactatgatggcctattacgagtggcacatctctatataatgggaaatgag
aaatgcagccagcatcatcgagggaaggtgactctgaatgagtctgaaatatgtgctggg
gctgaaaagattggatcaggaccatgtgagggggattatggtggcccacttgtttgtgag
caacataaaatgagaatggttcttggtgtcattgttcctggtcgtggatgtgccattcca
aatcgtcctggtatttttgtccgagtagcatattatgcaaaatggatacacaaaattatt
ttaacatataaggtaccacagtcatag

KEGG   Pan paniscus (bonobo): 100984583
Entry
100984583         CDS       T02283                                 

Gene name
PDGFB
Definition
(RefSeq) platelet derived growth factor subunit B
  KO
K17386  platelet-derived growth factor subunit B
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01521  EGFR tyrosine kinase inhibitor resistance
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04072  Phospholipase D signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04510  Focal adhesion
pps04540  Gap junction
pps04630  JAK-STAT signaling pathway
pps04810  Regulation of actin cytoskeleton
pps05167  Kaposi sarcoma-associated herpesvirus infection
pps05200  Pathways in cancer
pps05206  MicroRNAs in cancer
pps05211  Renal cell carcinoma
pps05214  Glioma
pps05215  Prostate cancer
pps05218  Melanoma
pps05231  Choline metabolism in cancer
pps05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100984583 (PDGFB)
   04014 Ras signaling pathway
    100984583 (PDGFB)
   04015 Rap1 signaling pathway
    100984583 (PDGFB)
   04630 JAK-STAT signaling pathway
    100984583 (PDGFB)
   04020 Calcium signaling pathway
    100984583 (PDGFB)
   04072 Phospholipase D signaling pathway
    100984583 (PDGFB)
   04151 PI3K-Akt signaling pathway
    100984583 (PDGFB)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100984583 (PDGFB)
   04540 Gap junction
    100984583 (PDGFB)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100984583 (PDGFB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100984583 (PDGFB)
   05206 MicroRNAs in cancer
    100984583 (PDGFB)
   05231 Choline metabolism in cancer
    100984583 (PDGFB)
  09162 Cancer: specific types
   05214 Glioma
    100984583 (PDGFB)
   05218 Melanoma
    100984583 (PDGFB)
   05211 Renal cell carcinoma
    100984583 (PDGFB)
   05215 Prostate cancer
    100984583 (PDGFB)
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    100984583 (PDGFB)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    100984583 (PDGFB)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100984583 (PDGFB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100984583 (PDGFB)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100984583 (PDGFB)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100984583 (PDGFB)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100984583 (PDGFB)
SSDB
Motif
Pfam: PDGF PDGF_N
Other DBs
NCBI-GeneID: 100984583
NCBI-ProteinID: XP_003821658
UniProt: A0A2R9ACQ2
Position
22
AA seq 241 aa
MNRCWALFLSLCCYLRLVSAEGDPIPEELYEMLSDHSIRSFDDLQRLLHGDPGEEDGAEL
DLNMTRSHSGGELESLARGRRSLGSLTVAEPAMIAECKTRTEVFEISRRLIDRTNANFLV
WPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKC
ETVAAARPVTRSPGGSQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLG
A
NT seq 726 nt   +upstreamnt  +downstreamnt
atgaatcgctgctgggcgctcttcctgtctctctgctgctacctgcgtctggtcagcgcc
gagggggaccccattcccgaggagctttatgagatgctgagtgaccactcgatccgctcc
tttgatgatctccaacgcctgctgcacggagaccccggagaggaagatggggccgagttg
gacctgaacatgacccgctcccactctggaggcgagctggagagcttggctcgtggaaga
aggagcctgggttccctgaccgttgctgagccggccatgatcgccgagtgcaagacgcgc
accgaggtgttcgagatctcccggcgcctcatagaccgcaccaacgccaacttcctggtg
tggccgccctgcgtggaggtgcagcgctgctccggctgctgcaacaaccgcaacgtgcag
tgccgccccacccaggtgcagctgcgacctgtccaggtgagaaagatcgagattgtgcgg
aagaagccaatctttaagaaggccacggtgacgctggaagaccacctggcatgcaagtgt
gagacagtggcagctgcacggcctgtgacccgaagcccggggggttcccaggagcagcga
gccaaaacgccccaaactcgggtgaccattcggacggtgcgagtccgccggccccccaag
ggcaagcaccggaaattcaagcacacgcatgacaagacggcactgaaggagaccctcgga
gcctag

KEGG   Pan paniscus (bonobo): 100985264
Entry
100985264         CDS       T02283                                 

Gene name
FGF16
Definition
(RefSeq) fibroblast growth factor 16
  KO
K04358  fibroblast growth factor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04810  Regulation of actin cytoskeleton
pps05200  Pathways in cancer
pps05218  Melanoma
pps05224  Breast cancer
pps05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100985264 (FGF16)
   04014 Ras signaling pathway
    100985264 (FGF16)
   04015 Rap1 signaling pathway
    100985264 (FGF16)
   04020 Calcium signaling pathway
    100985264 (FGF16)
   04151 PI3K-Akt signaling pathway
    100985264 (FGF16)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100985264 (FGF16)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100985264 (FGF16)
  09162 Cancer: specific types
   05226 Gastric cancer
    100985264 (FGF16)
   05218 Melanoma
    100985264 (FGF16)
   05224 Breast cancer
    100985264 (FGF16)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100985264 (FGF16)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100985264 (FGF16)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100985264 (FGF16)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100985264 (FGF16)
SSDB
Motif
Pfam: FGF
Other DBs
NCBI-GeneID: 100985264
NCBI-ProteinID: XP_003824449
UniProt: A0A2R9AZR1
Position
X
AA seq 207 aa
MAEVGGVFASLDWDLHGFSSSLGNVPLADSPGFLNERLGQIEGKLQRGSPTDFAHLKGIL
RRRQLYCRTGFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGLYLGMNER
GELYGSKKLTRECVFREQFEENWYNTYASTLYKHSDSERQYYVALNKDGSPREGYRTKRH
QKFTHFLPRPVDPSKLPSMSRDLFHYR
NT seq 624 nt   +upstreamnt  +downstreamnt
atggcagaggtggggggcgtcttcgcctccttggactgggatctacacggcttctcctcg
tctctggggaacgtgcccttagctgactccccaggtttcctgaacgagcgcctgggccaa
atcgaggggaagctgcagcgtggctcacccacagacttcgcccacctgaaggggatcctg
cggcgccgccagctctactgccgcaccggcttccacctggagatcttccccaacggcacg
gtgcacggcacccgccacgaccacagccgcttcggaatcctggagtttatcagcctggct
gtggggctgatcagcatccggggagtggactctggcctgtacctaggaatgaatgagcga
ggagaactctatgggtcgaagaaactcacacgtgaatgtgttttccgggaacagtttgaa
gaaaactggtacaacacctatgcctcaaccttgtacaaacattcggactcggagagacag
tattacgtggccctgaacaaagatggctcaccccgggagggatacaggactaaacgacac
cagaaattcactcactttttacccaggcctgtagatccttctaagttgccctccatgtcc
agagacctctttcactataggtaa

KEGG   Pan paniscus (bonobo): 100989491
Entry
100989491         CDS       T02283                                 

Gene name
FGF6
Definition
(RefSeq) fibroblast growth factor 6
  KO
K04358  fibroblast growth factor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04810  Regulation of actin cytoskeleton
pps05200  Pathways in cancer
pps05218  Melanoma
pps05224  Breast cancer
pps05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100989491 (FGF6)
   04014 Ras signaling pathway
    100989491 (FGF6)
   04015 Rap1 signaling pathway
    100989491 (FGF6)
   04020 Calcium signaling pathway
    100989491 (FGF6)
   04151 PI3K-Akt signaling pathway
    100989491 (FGF6)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100989491 (FGF6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100989491 (FGF6)
  09162 Cancer: specific types
   05226 Gastric cancer
    100989491 (FGF6)
   05218 Melanoma
    100989491 (FGF6)
   05224 Breast cancer
    100989491 (FGF6)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100989491 (FGF6)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100989491 (FGF6)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100989491 (FGF6)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100989491 (FGF6)
SSDB
Motif
Pfam: FGF
Other DBs
NCBI-GeneID: 100989491
NCBI-ProteinID: XP_003820386
UniProt: A0A2R9C1N8
Position
12
AA seq 208 aa
MALGQKLFITMSRGAGHLQGTLWALVFLGILVGMVVPSPAGTRANNTLLDSRGWGTLLSR
SRAGLAGEIAGVNWESGYLVGIKRQRRLYCNVGIGFHLQVLPDGRISGTHEENPYSLLEI
STVERGVVSLFGVRSALFVAMNSKGRLYATPSFQEECKFRETLLPNNYNAYESDLYRGTY
IALSKYGRVKRGSKVSPIMTVTHFLPRI
NT seq 627 nt   +upstreamnt  +downstreamnt
atggccctgggacagaaactgttcatcactatgtcccggggagcaggacatctgcagggc
acgctgtgggctctcgtcttcctaggcatcctagtgggcatggtggtgccctcgcctgca
ggcacccgtgccaacaacacgctgctggactcgaggggctggggcaccctgctgtccagg
tctcgcgccgggctagctggagagatcgccggggtgaactgggaaagtggctatttggtg
gggatcaagcggcagcggaggctctactgcaacgtgggcattggctttcacctccaggtg
ctccccgacggccggatcagcgggacccacgaggagaacccctacagcctgctggaaatt
tccaccgtggagcgaggcgtggtgagtctctttggagtgagaagtgccctcttcgttgcc
atgaacagtaaaggaagattgtacgcaacgcccagcttccaagaagaatgcaagttcaga
gaaaccctcctgcccaacaattacaatgcctacgagtcagacttgtaccgagggacctac
atcgccctgagcaaatacggacgggtaaagcggggcagcaaggtgtccccgatcatgact
gtcactcatttccttcccaggatctaa

KEGG   Pan paniscus (bonobo): 100989835
Entry
100989835         CDS       T02283                                 

Gene name
FGF23
Definition
(RefSeq) fibroblast growth factor 23
  KO
K22428  fibroblast growth factor 23
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04810  Regulation of actin cytoskeleton
pps04928  Parathyroid hormone synthesis, secretion and action
pps05200  Pathways in cancer
pps05218  Melanoma
pps05224  Breast cancer
pps05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100989835 (FGF23)
   04014 Ras signaling pathway
    100989835 (FGF23)
   04015 Rap1 signaling pathway
    100989835 (FGF23)
   04020 Calcium signaling pathway
    100989835 (FGF23)
   04151 PI3K-Akt signaling pathway
    100989835 (FGF23)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100989835 (FGF23)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    100989835 (FGF23)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100989835 (FGF23)
  09162 Cancer: specific types
   05226 Gastric cancer
    100989835 (FGF23)
   05218 Melanoma
    100989835 (FGF23)
   05224 Breast cancer
    100989835 (FGF23)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100989835 (FGF23)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100989835 (FGF23)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100989835 (FGF23)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100989835 (FGF23)
SSDB
Motif
Pfam: FGF
Other DBs
NCBI-GeneID: 100989835
NCBI-ProteinID: XP_003820387
UniProt: A0A2R9AWI6
Position
12
AA seq 251 aa
MLGARLRLWVCALCSVCSVSVLRAYPNASPLLGSSWGGLIHLYTATARNSYHLQIHKNGH
VDGAPHQTIYSALMIRSEDAGFVVITGVMSRRYLCMDFRGNIFGSHYFNPENCRFQHQTL
ENGYDVYYSPQYHFLVSLGRAKRAFLPSMNPPPYSQFLSRRNEIPLIHFNTPIPRRHTRS
AEDDSERDPLNVLKPRARMTPAPASCSQELPSAEDNSPMASDPLGVVRGGRVNTHAGGTG
PEGCRPFPKFI
NT seq 756 nt   +upstreamnt  +downstreamnt
atgttgggggcccgcctcaggctctgggtctgtgccttgtgcagtgtctgcagcgtgagc
gtcctcagagcctaccccaatgcctccccactgctcggctccagctggggtggcctgatc
cacctgtacacagccacagccaggaacagctaccacctgcagatccacaagaatggccat
gtggatggcgcaccccatcagaccatctacagtgccctgatgatcagatcagaggatgct
ggctttgtggtgattacaggtgtgatgagcagaagatacctctgcatggatttcagaggc
aacatttttggatcacactatttcaacccggagaactgcaggttccaacaccagacgctg
gaaaacgggtacgacgtctactactctcctcagtatcacttcctggtcagtctgggccgg
gcgaagagagccttcctgccaagcatgaacccacccccgtactcccagttcctgtcccgg
aggaacgagatccccctaattcacttcaacacccccataccacggcggcacacccggagc
gccgaggacgactcggagcgggaccccctgaacgtgctgaagccccgggcccggatgacc
ccggccccggcctcctgttcacaggagctcccgagcgccgaggacaacagcccgatggcc
agtgacccattaggggtggtcaggggcggtcgagtgaacacgcacgctgggggaacgggc
ccggaaggctgccgccccttccccaagttcatctag

KEGG   Pan paniscus (bonobo): 100990660
Entry
100990660         CDS       T02283                                 

Gene name
VEGFC
Definition
(RefSeq) vascular endothelial growth factor C
  KO
K05449  vascular endothelial growth factor C/D
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04510  Focal adhesion
pps04668  TNF signaling pathway
pps04926  Relaxin signaling pathway
pps04933  AGE-RAGE signaling pathway in diabetic complications
pps05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100990660 (VEGFC)
   04014 Ras signaling pathway
    100990660 (VEGFC)
   04015 Rap1 signaling pathway
    100990660 (VEGFC)
   04668 TNF signaling pathway
    100990660 (VEGFC)
   04020 Calcium signaling pathway
    100990660 (VEGFC)
   04151 PI3K-Akt signaling pathway
    100990660 (VEGFC)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100990660 (VEGFC)
 09150 Organismal Systems
  09152 Endocrine system
   04926 Relaxin signaling pathway
    100990660 (VEGFC)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100990660 (VEGFC)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100990660 (VEGFC)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100990660 (VEGFC)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100990660 (VEGFC)
SSDB
Motif
Pfam: PDGF CXCXC
Other DBs
NCBI-GeneID: 100990660
NCBI-ProteinID: XP_003823486
UniProt: A0A2R9CHL8
Position
4
AA seq 418 aa
MHLLGFFSVACSLLAAALLPGPREAPAAAAFESGLDLSDAEPDAGEATAYASKDLEEQLR
SVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLNSRTEETIKFAAAHYNTEILKS
IDNEWRKTQCMPREVCIDVGKEFGVATNTFFKPPCVSIYRCGGCCNSEGLQCMNTSTSYL
SKTLFEITVPLSQGPKPVTISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANK
TCPTNYMWNNHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGLRP
ASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPRNQPLNPGKCACE
CTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEPGFSYSEEVCRCVPSYWKRPQMS
NT seq 1257 nt   +upstreamnt  +downstreamnt
atgcacttgctgggcttcttctctgtggcgtgttctctgctcgccgctgcgctgctcccg
ggtcctcgcgaggcgcccgccgccgccgccttcgagtccggactcgacctctcggacgcg
gagcccgacgcgggcgaggccacggcttatgcaagcaaagatctggaggagcagttacgg
tctgtgtccagtgtagatgaactcatgactgtactctacccagaatattggaaaatgtac
aagtgtcagctaaggaaaggaggctggcaacataacagagaacaggccaacctcaactca
aggacagaagagactataaaatttgctgcagcacattataatacagagatcttgaaaagt
attgataatgagtggagaaagactcaatgcatgccacgggaggtgtgtatagatgtgggg
aaggagtttggagtcgcaacaaacaccttctttaaacctccatgtgtgtccatctacaga
tgtgggggttgctgcaacagtgaggggctgcagtgcatgaacaccagcacgagctacctc
agcaagacgttatttgaaattacagtgcctctctctcaaggccccaaaccagtaacaatc
agttttgccaatcacacttcctgccgatgcatgtctaaactggatgtttacagacaagtt
cattccattattagacgttccctgccagcaacactaccacagtgtcaggcagcgaacaag
acctgccccaccaattacatgtggaataatcacatctgcagatgcctggctcaggaagat
tttatgttttcctcggatgctggagatgactcaacagatggattccatgacatctgtgga
ccaaacaaggagctggatgaagagacctgtcagtgtgtctgcagagcggggcttcggcct
gccagctgtggaccccacaaagaactagacagaaactcatgccagtgtgtctgtaaaaac
aaactcttccccagccaatgtggggccaaccgagaatttgatgaaaacacatgccagtgt
gtatgtaaaagaacctgccccagaaatcaacccctaaatcctggaaaatgtgcctgtgaa
tgtacagaaagtccacagaaatgcttgttaaaaggaaagaagttccaccaccaaacatgc
agctgttacagacggccatgtacgaaccgccagaaggcttgtgagccaggattttcatat
agtgaagaagtgtgtcgttgtgtcccttcatattggaaaagaccacaaatgagctaa

KEGG   Pan paniscus (bonobo): 100991389
Entry
100991389         CDS       T02283                                 

Gene name
PDGFA
Definition
(RefSeq) platelet derived growth factor subunit A
  KO
K04359  platelet-derived growth factor subunit A
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01521  EGFR tyrosine kinase inhibitor resistance
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04072  Phospholipase D signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04510  Focal adhesion
pps04540  Gap junction
pps04630  JAK-STAT signaling pathway
pps04810  Regulation of actin cytoskeleton
pps05200  Pathways in cancer
pps05202  Transcriptional misregulation in cancer
pps05206  MicroRNAs in cancer
pps05214  Glioma
pps05215  Prostate cancer
pps05218  Melanoma
pps05231  Choline metabolism in cancer
pps05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100991389 (PDGFA)
   04014 Ras signaling pathway
    100991389 (PDGFA)
   04015 Rap1 signaling pathway
    100991389 (PDGFA)
   04630 JAK-STAT signaling pathway
    100991389 (PDGFA)
   04020 Calcium signaling pathway
    100991389 (PDGFA)
   04072 Phospholipase D signaling pathway
    100991389 (PDGFA)
   04151 PI3K-Akt signaling pathway
    100991389 (PDGFA)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100991389 (PDGFA)
   04540 Gap junction
    100991389 (PDGFA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100991389 (PDGFA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100991389 (PDGFA)
   05202 Transcriptional misregulation in cancer
    100991389 (PDGFA)
   05206 MicroRNAs in cancer
    100991389 (PDGFA)
   05231 Choline metabolism in cancer
    100991389 (PDGFA)
  09162 Cancer: specific types
   05214 Glioma
    100991389 (PDGFA)
   05218 Melanoma
    100991389 (PDGFA)
   05215 Prostate cancer
    100991389 (PDGFA)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    100991389 (PDGFA)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100991389 (PDGFA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100991389 (PDGFA)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100991389 (PDGFA)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100991389 (PDGFA)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100991389 (PDGFA)
SSDB
Motif
Pfam: PDGF PDGF_N
Other DBs
NCBI-GeneID: 100991389
NCBI-ProteinID: XP_008971359
Position
7
AA seq 192 aa
MAGAVRGCAARCLFPSGSQSWSVGSAAGQAQGTAHGPGAFTVLSFTVPAGSEDSLDTSLR
VHGVHATKHAPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCV
EVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATTSL
NPDYREEDTDVR
NT seq 579 nt   +upstreamnt  +downstreamnt
atggcaggagctgtgaggggctgtgccgccaggtgcctgttccccagtggctcccaaagc
tggtctgtgggaagtgcggctggacaggcccagggcacagcgcacgggcctggagcattc
acggtgctctccttcacggtgcctgcagggagtgaggattctttggacaccagcctgaga
gttcacggggtccacgccactaagcatgcgcccgagaagcggcccctgcccattcgaagg
aagagaagcatcgaggaagctgtccccgctgtctgcaagaccaggacggtcatttacgag
attcctcggagtcaggtcgaccccacatccgccaacttcctgatctggcccccgtgcgtg
gaggtgaaacgctgcaccggctgctgcaacacgagcagtgtcaagtgccagccctcccgt
gtccaccaccgcagcgtcaaggtggccaaggtggaatacgtcaggaagaagccaaaatta
aaagaagtccaggtgaggttagaggagcatttggagtgcgcctgcgcgaccaccagcctg
aatccggattatcgggaagaggacacggatgtgaggtga

KEGG   Pan paniscus (bonobo): 100992612
Entry
100992612         CDS       T02283                                 

Gene name
FGF10
Definition
(RefSeq) fibroblast growth factor 10
  KO
K04358  fibroblast growth factor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04810  Regulation of actin cytoskeleton
pps05200  Pathways in cancer
pps05218  Melanoma
pps05224  Breast cancer
pps05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100992612 (FGF10)
   04014 Ras signaling pathway
    100992612 (FGF10)
   04015 Rap1 signaling pathway
    100992612 (FGF10)
   04020 Calcium signaling pathway
    100992612 (FGF10)
   04151 PI3K-Akt signaling pathway
    100992612 (FGF10)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100992612 (FGF10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100992612 (FGF10)
  09162 Cancer: specific types
   05226 Gastric cancer
    100992612 (FGF10)
   05218 Melanoma
    100992612 (FGF10)
   05224 Breast cancer
    100992612 (FGF10)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100992612 (FGF10)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100992612 (FGF10)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100992612 (FGF10)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100992612 (FGF10)
SSDB
Motif
Pfam: FGF Fascin
Other DBs
NCBI-GeneID: 100992612
NCBI-ProteinID: XP_003811059
UniProt: A0A2R9BWJ8
Position
5
AA seq 208 aa
MWKWILTHCASAFPHLPGCCCCCFLLLFLVSSVPVTCQALGQDMVSPEATNSSSSSFSSP
SSAGRHVRSYNHLQGDVRWRKLFSFTKYFLKIEKNGKVSGTKKENCPYSILEITSVEIGV
VAVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKERIEENGYNTYASFNWQHNGRQMYVAL
NGKGAPRRGQKTRRKNTSAHFLPMVVHS
NT seq 627 nt   +upstreamnt  +downstreamnt
atgtggaaatggatactgacacattgtgcctcagcctttccccacctgcccggctgctgc
tgctgctgctttttgttgctgttcttggtgtcttccgtccctgtcacctgccaagccctt
ggtcaggacatggtgtcaccagaggccaccaactcttcttcctcctccttctcctctcct
tccagcgcgggaaggcatgtgcggagctacaatcaccttcaaggagatgtccgctggaga
aagctattctctttcaccaagtactttctcaagattgagaagaacgggaaggtcagcggt
accaagaaggagaactgcccgtacagcatcctggagataacatcagtagaaatcggagtt
gttgccgtcaaagccattaacagcaactattacttagccatgaacaagaaggggaaactc
tatggctcaaaagaatttaacaatgactgtaagctgaaggagaggatagaggaaaatgga
tacaatacctatgcatcatttaactggcagcataatgggaggcaaatgtatgtggcattg
aatggaaaaggagctccaaggagaggacagaaaacacgaaggaaaaacacctctgctcac
tttcttccaatggtggtacactcatag

KEGG   Pan paniscus (bonobo): 100992738
Entry
100992738         CDS       T02283                                 

Gene name
PDGFD
Definition
(RefSeq) platelet derived growth factor D
  KO
K05450  platelet derived growth factor C/D
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01521  EGFR tyrosine kinase inhibitor resistance
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04072  Phospholipase D signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04510  Focal adhesion
pps04540  Gap junction
pps04810  Regulation of actin cytoskeleton
pps05215  Prostate cancer
pps05218  Melanoma
pps05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100992738 (PDGFD)
   04014 Ras signaling pathway
    100992738 (PDGFD)
   04015 Rap1 signaling pathway
    100992738 (PDGFD)
   04020 Calcium signaling pathway
    100992738 (PDGFD)
   04072 Phospholipase D signaling pathway
    100992738 (PDGFD)
   04151 PI3K-Akt signaling pathway
    100992738 (PDGFD)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100992738 (PDGFD)
   04540 Gap junction
    100992738 (PDGFD)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100992738 (PDGFD)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    100992738 (PDGFD)
  09162 Cancer: specific types
   05218 Melanoma
    100992738 (PDGFD)
   05215 Prostate cancer
    100992738 (PDGFD)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100992738 (PDGFD)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100992738 (PDGFD)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100992738 (PDGFD)
SSDB
Motif
Pfam: CUB PDGF
Other DBs
NCBI-GeneID: 100992738
NCBI-ProteinID: XP_003828415
Position
11
AA seq 370 aa
MHRLIFVYTLICANFCSCRDTSATPQSASIKALRNANLRRDESNHLTDLYRRDETIQVKG
NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS
ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQPAAASE
TNWESVTSSISGVSYNSPSVTDPTLIADALDKKIAEFDTVEDLLKYFNPESWQEDLENMY
LDTPRYRGRSYHDRKSKVDLDRLNDDAKRYSCTPRNYSVNIREELKLANVVFFPRCLLVQ
RCGGNCGCGTVNWRSCTCNSGKTVKKYHEVLQFEPGHIKRRGRAKTMALVDIQLDHHERC
DCICSSRPPR
NT seq 1113 nt   +upstreamnt  +downstreamnt
atgcaccggctcatctttgtctacactctaatctgcgcaaacttttgcagctgtcgggac
acttctgcaactccgcagagcgcatccatcaaagctttgcgcaacgccaacctcaggcga
gatgagagcaatcacctcacagacttgtaccgaagagatgagaccatccaggtgaaagga
aacggctacgtgcagagtcctagattcccgaacagctaccccaggaacctgctcctgaca
tggcggcttcactctcaggagaatacacggatacagctagtgtttgacaatcagtttgga
ttagaggaagcagaaaatgatatctgtaggtatgattttgtggaagttgaagatatatct
gaaaccagtaccattattagaggacgatggtgtggacacaaggaagttcctccaaggata
aaatcaagaacgaaccaaattaaaatcacattcaagtccgatgactactttgtggctaaa
cctggattcaagatttattattctttgctggaagattttcaacccgcagcagcttcagag
accaactgggaatctgtcacaagctctatttcaggggtatcctataactctccatcagta
acggatcccactctgattgcggatgctctggacaaaaaaattgcagaatttgatacagtg
gaagatctgctcaagtacttcaatccagagtcatggcaagaagatcttgagaatatgtat
ctggacacccctcgttatcgaggcaggtcataccatgaccggaagtcaaaagttgacctg
gataggctcaatgatgatgccaagcgttacagttgcactcccaggaattactcggtcaat
ataagagaagagctgaagttggccaatgtggtcttctttccacgttgcctcctcgtgcag
cgctgtggaggaaattgtggctgtggaactgtcaactggaggtcctgcacatgcaattca
gggaaaaccgtgaaaaagtatcatgaggtattacagtttgagcctggccacatcaagagg
aggggtagagctaagaccatggctctagttgacatccagttggatcaccatgaacgatgc
gattgtatctgcagctcaagaccacctcgataa

KEGG   Pan paniscus (bonobo): 100992953
Entry
100992953         CDS       T02283                                 

Gene name
FGF18
Definition
(RefSeq) fibroblast growth factor 18
  KO
K04358  fibroblast growth factor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04810  Regulation of actin cytoskeleton
pps05200  Pathways in cancer
pps05218  Melanoma
pps05224  Breast cancer
pps05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100992953 (FGF18)
   04014 Ras signaling pathway
    100992953 (FGF18)
   04015 Rap1 signaling pathway
    100992953 (FGF18)
   04020 Calcium signaling pathway
    100992953 (FGF18)
   04151 PI3K-Akt signaling pathway
    100992953 (FGF18)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100992953 (FGF18)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100992953 (FGF18)
  09162 Cancer: specific types
   05226 Gastric cancer
    100992953 (FGF18)
   05218 Melanoma
    100992953 (FGF18)
   05224 Breast cancer
    100992953 (FGF18)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100992953 (FGF18)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100992953 (FGF18)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100992953 (FGF18)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100992953 (FGF18)
SSDB
Motif
Pfam: FGF
Other DBs
NCBI-GeneID: 100992953
NCBI-ProteinID: XP_003811000
Position
5
AA seq 408 aa
MPLEGAEAVRTSVLNGALVKGTKLPGMQTEASLSPVLGGGRKRASAWSLTRVLLAAPRRA
AVRAGVAVTSRGRLVVAVCFQSWLAYGRVQLGSREPTPEPRRGRGVGRRDAPEPPSQRQG
REDVPYLTAFLGSIACPIWATFARRSGHCARAQSSDGFQRSPASVSRVLPLRSCRSRLRE
SERLPSNPEPPEGGGGSERPRQAGEQAGPPLMCLHFLLLCFQVQVLVAEENVDFRIHVEN
QTRARDDVSRKQLRLYQLYSRTSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRI
KGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRP
RKGPKTRENQQDVHFMKRYPKGQPELQKPFKYTTVTKRSRRIRPTHPA
NT seq 1227 nt   +upstreamnt  +downstreamnt
atgcctctggaaggggcagaggcggtaagaaccagtgtcctgaatggggccctggttaaa
ggaacgaagctgcctggtatgcaaacggaggcaagtcttagtccggttttgggaggaggc
cggaagagggcctcagcgtggtcgctgaccagagtcctgctggctgctccccggcgtgca
gccgtccgtgctggggttgcagtgacgtctcggggccgcttggtggtagccgtgtgtttc
caaagctggctcgcctacgggagagtccagctgggatcccgtgaaccgaccccagagccc
cggagggggcgaggggtgggaaggagagatgccccggagcccccttcgcagcggcaggga
cgtgaggacgttccgtacctaactgcgttcttggggagcatcgcctgcccaatttgggca
acgtttgcgcggaggagcggtcactgcgctcgggcgcagagctccgacggcttccagcgc
tcaccagcttcagtctcgcgggtcctgccccttcggagctgccggtcccgtctccgagag
tctgagcgcctcccctccaaccccgagccgccagaaggaggaggaggcagcgagaggccg
cggcaggcaggcgagcaggcagggccgcctttgatgtgtttacacttcctgctgctgtgc
ttccaggtacaggtgctggttgccgaggagaacgtggacttccgcatccacgtggagaac
cagacgcgggctcgggacgatgtgagccgtaagcagctgcggctgtaccagctctacagc
cggaccagtgggaaacacatccaggtcctgggccgcaggatcagtgcccgcggcgaggat
ggggacaagtatgcccagctcctagtggagacagacaccttcggtagtcaagtccggatc
aagggcaaggagacggaattctacctgtgcatgaaccgcaaaggcaagctcgtggggaag
cccgatggcaccagcaaggagtgtgtgttcatcgagaaggttctggagaacaactacacg
gccctgatgtcggctaagtactccggctggtacgtgggcttcaccaagaaggggcggccg
cggaagggccccaagacccgggagaaccagcaggacgtgcatttcatgaagcgctacccc
aaggggcagccggagcttcagaagcccttcaagtacacgacggtgaccaagaggtcccgt
cggatccggcccacacaccccgcctag

KEGG   Pan paniscus (bonobo): 100995394
Entry
100995394         CDS       T02283                                 

Gene name
FGF7
Definition
(RefSeq) fibroblast growth factor 7
  KO
K04358  fibroblast growth factor
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04151  PI3K-Akt signaling pathway
pps04810  Regulation of actin cytoskeleton
pps05200  Pathways in cancer
pps05218  Melanoma
pps05224  Breast cancer
pps05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100995394 (FGF7)
   04014 Ras signaling pathway
    100995394 (FGF7)
   04015 Rap1 signaling pathway
    100995394 (FGF7)
   04020 Calcium signaling pathway
    100995394 (FGF7)
   04151 PI3K-Akt signaling pathway
    100995394 (FGF7)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100995394 (FGF7)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100995394 (FGF7)
  09162 Cancer: specific types
   05226 Gastric cancer
    100995394 (FGF7)
   05218 Melanoma
    100995394 (FGF7)
   05224 Breast cancer
    100995394 (FGF7)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100995394 (FGF7)
   00536 Glycosaminoglycan binding proteins [BR:pps00536]
    100995394 (FGF7)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100995394 (FGF7)
Glycosaminoglycan binding proteins [BR:pps00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100995394 (FGF7)
SSDB
Motif
Pfam: FGF Fascin Gb3_synth
Other DBs
NCBI-GeneID: 100995394
NCBI-ProteinID: XP_003831549
UniProt: A0A2R9BET1
Position
15
AA seq 194 aa
MHKWILTWILPTLLYRSCFHIICLVGTISLACNDMTPEQMATNVNCSSPERHTRSYDYME
GGDIRVRRLFCRTQWYLRIDKRGKVKGTQEMKNNYNIMEIRTVAVGIVAIKGVESEFYLA
MNKEGKLYAKKECNEDCNFKELILENHYNTYASAKWTHNGGEMFVALNQKGIPVRGKKTK
KEQKTAHFLPMAIT
NT seq 585 nt   +upstreamnt  +downstreamnt
atgcacaaatggatactgacatggatcctgccaactttgctctacagatcatgctttcac
attatctgtctagtgggtactatatctttagcttgcaatgacatgactccagagcaaatg
gctacaaatgtgaactgttccagccctgagcgacacacaagaagttatgattacatggaa
ggaggggatataagagtgagaagactcttctgtcgaacacagtggtacctgaggatcgat
aaaagaggcaaagtaaaagggacccaagagatgaagaataattacaatatcatggaaatc
aggacagtggcagttggaattgtggcaatcaaaggggtggaaagtgaattctatcttgca
atgaacaaggaaggaaaactctatgcaaagaaagaatgcaatgaagattgtaacttcaaa
gaactaattctggaaaaccattacaacacatatgcatcagctaaatggacacacaacgga
ggggaaatgtttgttgccttaaatcaaaaggggattcctgtaagaggaaaaaaaacgaag
aaagaacaaaaaacagcccactttcttcctatggcaataacttaa

KEGG   Pan paniscus (bonobo): 100995667
Entry
100995667         CDS       T02283                                 

Gene name
NGF
Definition
(RefSeq) nerve growth factor
  KO
K02582  nerve growth factor, beta
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04015  Rap1 signaling pathway
pps04020  Calcium signaling pathway
pps04060  Cytokine-cytokine receptor interaction
pps04151  PI3K-Akt signaling pathway
pps04210  Apoptosis
pps04722  Neurotrophin signaling pathway
pps04750  Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100995667 (NGF)
   04014 Ras signaling pathway
    100995667 (NGF)
   04015 Rap1 signaling pathway
    100995667 (NGF)
   04020 Calcium signaling pathway
    100995667 (NGF)
   04151 PI3K-Akt signaling pathway
    100995667 (NGF)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100995667 (NGF)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    100995667 (NGF)
 09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100995667 (NGF)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100995667 (NGF)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:pps03110]
    100995667 (NGF)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:pps04052]
    100995667 (NGF)
Chaperones and folding catalysts [BR:pps03110]
 Intramolecular chaperones
  Others
   100995667 (NGF)
Cytokines and growth factors [BR:pps04052]
 Growth factors
  Growth factors (RTK binding)
   100995667 (NGF)
SSDB
Motif
Pfam: NGF Spaetzle NTF3_N
Other DBs
NCBI-GeneID: 100995667
NCBI-ProteinID: XP_003805679
Position
1
AA seq 241 aa
MSMLFYTLITAFLIGTQAEPHSESNVPAGHTIPQAHWTKLQHSLDTALRRARSAPAAAIA
ARVAGQTHNITVDPRLFKKRRLRSPRVLFSTQPPPEAADTQDLDFEVGGATPFNRTHRSK
RSSSHPIFHRGEFSVCDSVSVWVGDKTTATDIKGKEVMVLGEVNINNSVFKQYFFETKCR
DPNPVDSGCRGIDSKHWNSYCTTTHTFVKALTMDGKQAAWRFIRIDTACVCVLSRKAVRR
A
NT seq 726 nt   +upstreamnt  +downstreamnt
atgtccatgttgttctacactctgatcacagcttttctgatcggcacacaggcggaacca
cactcagagagcaatgtccctgcaggacacaccatcccccaagcccactggactaaactt
cagcattcccttgacactgcccttcgcagagcccgcagcgccccggcagcagcgatagct
gcacgtgtggcagggcagacccacaacattactgtggaccccaggctgtttaaaaagcgg
cgactccgttcaccccgtgtgctgtttagcacccagcccccacctgaagctgcagacact
caggatctggacttcgaggtcggtggtgctacccccttcaacaggactcacaggagcaag
cggtcatcatcccatcccatcttccacaggggcgaattctcggtgtgtgacagtgtcagc
gtgtgggttggggataagaccaccgccacagacatcaagggcaaggaggtgatggtgttg
ggagaggtgaacattaacaacagtgtattcaaacagtacttttttgagaccaagtgccgg
gacccaaatcccgttgacagcgggtgccggggcattgactcaaagcactggaactcatat
tgtaccacgactcacacctttgtcaaggcgctgaccatggatggcaagcaggctgcctgg
cggtttatccggatagatacggcctgtgtgtgtgtgctcagcaggaaggctgtgagaaga
gcctga

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