KEGG   Pongo pygmaeus (Bornean orangutan): 129036974
Entry
129036974         CDS       T10128                                 
Symbol
APC
Name
(RefSeq) adenomatous polyposis coli protein isoform X1
  KO
K02085  adenomatosis polyposis coli protein
Organism
ppyg  Pongo pygmaeus (Bornean orangutan)
Pathway
ppyg04310  Wnt signaling pathway
ppyg04390  Hippo signaling pathway
ppyg04519  Cadherin signaling
ppyg04550  Signaling pathways regulating pluripotency of stem cells
ppyg04810  Regulation of actin cytoskeleton
ppyg04934  Cushing syndrome
ppyg05010  Alzheimer disease
ppyg05022  Pathways of neurodegeneration - multiple diseases
ppyg05165  Human papillomavirus infection
ppyg05200  Pathways in cancer
ppyg05206  MicroRNAs in cancer
ppyg05210  Colorectal cancer
ppyg05213  Endometrial cancer
ppyg05217  Basal cell carcinoma
ppyg05224  Breast cancer
ppyg05225  Hepatocellular carcinoma
ppyg05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ppyg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    129036974 (APC)
   04390 Hippo signaling pathway
    129036974 (APC)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    129036974 (APC)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    129036974 (APC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    129036974 (APC)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    129036974 (APC)
   05206 MicroRNAs in cancer
    129036974 (APC)
  09162 Cancer: specific types
   05210 Colorectal cancer
    129036974 (APC)
   05225 Hepatocellular carcinoma
    129036974 (APC)
   05226 Gastric cancer
    129036974 (APC)
   05217 Basal cell carcinoma
    129036974 (APC)
   05213 Endometrial cancer
    129036974 (APC)
   05224 Breast cancer
    129036974 (APC)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    129036974 (APC)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    129036974 (APC)
   05022 Pathways of neurodegeneration - multiple diseases
    129036974 (APC)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    129036974 (APC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ppyg01009]
    129036974 (APC)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:ppyg03036]
    129036974 (APC)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:ppyg04812]
    129036974 (APC)
Protein phosphatases and associated proteins [BR:ppyg01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     129036974 (APC)
Chromosome and associated proteins [BR:ppyg03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    129036974 (APC)
Cytoskeleton proteins [BR:ppyg04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     129036974 (APC)
SSDB
Motif
Pfam: Arm_APC_u3 APC_basic EB1_binding APC_r APC_u5 APC_u14 APC_rep APC_u15 APC_u9 SAMP Arm APC_u13 APC_15aa Suppressor_APC ARM_ARMC5 ZER1-like_2nd Sec7-like_HUS
Other DBs
NCBI-GeneID: 129036974
NCBI-ProteinID: XP_054344690
Position
4:116928062..117067505
AA seq 2872 aa
MYASLGSGPVAALPASVPPSTLGSWSTGGSRSCVRQETKSPGGARTSGHWASVWQEVLKQ
LQGSIEDEAMASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGEC
SPVPMGSFPRRGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRID
SLPLTENFSLQTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILR
IRQLLQSQATEAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETAS
VLSSSSTHSAPRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQS
GCLPLLIQLLHGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLL
EQIRAYCETCWEWQEAHEQGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELG
RKATRGISSQELGQGLSGGLQAIAELLQVDCEMYGLTNDHYSITLRRYAGMALTNLTFGD
VANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKAL
MECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAII
ESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNP
KDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDANIMSPGSSLPSL
HVRKQKALEAELDAQHLSETFDNIDNLSPKASHRSKQRHKQSLYGDYVFDTNRHDDNRSD
NFNTGNMTVLSPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLGNYHPATENPGT
SSKRGLQISTTAAQIAKVMEEVSAIHTSQEDRSSGSTTELHCVTDERNALRRSSAAHTHS
NTYSFTKSENSNRTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDES
KFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARP
KHIIEDEIKQSEQRQSRNQSTTYPVYTESTDDKHLKFQPHFGQQECVSPYRSRGANGSET
NRVGSNHGINQNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEEKHH
VDQPIDYSLKYTTDIPSSQKQSFSFSKSSSGQSTKTEHMSSSSENTSTPSSNAKRQNQLH
PSSAQSRSGQTQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCGQT
TQEADSANTLQIAEIKEKIVTRSTEDPVSEVPAVSQHTRTKSSRLQGSNLSSESARHKAV
EFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSG
MVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAAV
NAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQEND
NGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAK
KPAQTASKLPPPVARKPSQLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFS
TATSLSDLTIESPPNELAVGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPE
LDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKKP
TSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFPDNKDSKKQNLKNNSKDFNDKVPNNED
RVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKESEA
KVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDEKLQ
NFAIENTPVCFSHNSSLSSLSDIDQENNNNKENEPVKETEPPDSQGEPSKPQASGYAPKS
FHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGI
LAEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSD
SDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGG
KKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGP
PLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSR
PAQQPLSRPMQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGR
QMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDR
SERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDM
SLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREH
SKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGT
WRKIKENEISPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRS
GRSPTGNTPPVIDSVSEKGNPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAP
DQKGTETKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPR
KSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYLVTSV
NT seq 8619 nt   +upstreamnt  +downstreamnt
atgtacgcctccctgggctcgggtccggtcgccgctttgcccgcttctgtaccaccctca
actctcgggtcctggagcaccggcggcagcaggagctgcgtccggcaggagacgaagagc
ccaggcggcgctcgtacttctggccactgggcgagcgtctggcaggaagtacttaaacaa
ctacaaggaagtattgaagatgaagctatggcttcttctggacagattgatttattagag
cgtcttaaagagcttaacttagatagcagtaatttccctggagtaaaactacggtcaaaa
atgtccctccgttcttatggaagccgggaaggatctgtatcaagccgttctggagagtgc
agtcctgttcctatgggttcatttccaagaagagggtttgtaaatggaagcagagaaagt
actggatatttagaagaacttgagaaagagaggtcattgcttcttgctgatcttgacaaa
gaagaaaaggaaaaagactggtattacgctcaacttcagaatctcactaaaagaatagat
agtcttcctttaactgaaaatttttctttacaaacagatatgaccagaaggcaattggaa
tatgaagcgaggcaaatcagagttgcgatggaagaacaactaggtacctgccaggatatg
gaaaaacgagcacagcgaagaatagccagaattcagcaaatcgaaaaggacatacttcgt
atacgacagcttttacagtcccaagcaacagaagctgagaggtcatctcagaacaagcat
gaaaccggctcacatgatgctgagcggcagaatgaaggtcaaggagtgggagaaatcaac
atggcaacttctggtaatggtcagggttcaactacacgaatggaccacgaaacagccagt
gttttgagttctagtagcacacactctgcacctcgaaggctgacaagtcatctgggaacc
aaggtggaaatggtgtattcattgttgtcaatgcttggtactcatgataaggatgatatg
tcgcgaactttgctagctatgtctagctcccaagacagctgtatatccatgcgacagtct
ggatgtcttcctctcctcatccagcttttacatggcaatgacaaagactctgtattgttg
ggaaattcccggggcagtaaagaggctcgggccagggccagtgcagcactccacaacatc
attcactcacagcctgatgacaagagaggcaggcgtgaaatccgagtccttcatcttttg
gaacagatacgcgcttactgtgaaacctgttgggagtggcaggaagctcatgaacaaggc
atggaccaggacaaaaatccaatgccagctcctgttgaacatcagatctgtcctgctgtg
tgtgttctaatgaaactttcatttgatgaagagcatagacatgcaatgaatgaactaggt
aggaaggctacccggggcatttcatcacaggagctagggcaggggctttcagggggacta
caggccattgcagaattattgcaagtggactgtgaaatgtatgggcttaccaatgaccac
tacagtattacactaagacgatatgctggaatggctttgacaaacttgacttttggagat
gtagccaacaaggctacgctatgctctatgaaaggctgcatgagagcacttgtggcccaa
ctaaaatctgaaagtgaagacttacagcaggttattgcaagtgttttgaggaatttgtct
tggcgagcagatgtaaatagtaaaaagacattgcgggaagttggaagtgtgaaagcattg
atggaatgtgctttagaagttaaaaaggaatcaaccctcaaaagcgtattgagtgcctta
tggaatttgtcagcacattgcactgagaataaagctgatatatgtgctgtagatggtgca
cttgcatttttggttggcactcttacttaccggagccagacaaacactttagccattatt
gaaagtggaggtgggatattacggaatgtgtccagcttgatagctacaaatgaggaccac
aggcaaatcctaagagagaacaactgtctacaaactttattacaacacttaaaatctcat
agtttgacaatagtcagtaatgcatgtggaactttgtggaatctctcagcaagaaaccct
aaagaccaggaagcattatgggacatgggggcagttagcatgctcaagaacctcattcat
tcaaagcacaaaatgattgctatgggaagtgctgcagctttaaggaatctcatggcaaat
aggcctgcgaagtacaaggatgccaatattatgtctcctggctcaagcttgccatctctt
catgttaggaaacaaaaagccctagaagcagaattagatgctcagcatttatcagaaact
tttgacaatatagacaatttaagtcccaaggcatctcatcgtagtaagcaaagacacaag
caaagtctctatggtgattatgtttttgacaccaatcgacatgatgataataggtcagac
aattttaatactggcaacatgactgtcctttcaccatatttgaatactacagtgttaccc
agctcctcttcatcaagaggaagcttagatagttctcgttctgaaaaagatagaagtttg
gagagagaacgaggaattggtctaggcaactaccatccagcaacagaaaatccaggaacc
tcttcaaagcgaggtttgcagatctccaccactgcagcccagattgccaaagtcatggaa
gaagtgtcagctattcatacctctcaggaagacagaagttctgggtccaccactgaatta
cattgtgtgacagatgagagaaatgcacttagaagaagctctgctgcccatacacattca
aacacttacagtttcactaagtcagaaaattcaaataggacatgttctatgccttatgcc
aaattagaatacaagagatcttcaaatgatagtttaaatagtgtcagtagtagtgatggt
tatggtaaaagaggtcaaatgaaaccctcaattgaatcctattctgaagatgatgaaagt
aagttttgcagttatggtcaatacccagccgacctagcccataaaatacatagtgcaaat
catatggatgataatgatggagaactagatacaccaataaattatagtcttaaatattca
gatgagcagttgaactctggaaggcaaagtccttcacagaatgaaagatgggcaagaccc
aaacacataatagaagatgaaataaaacaaagtgagcaaagacaatcaaggaatcaaagt
acaacttatcctgtttatactgagagcactgatgataaacacctcaagttccaaccacat
tttggacagcaggaatgtgtttctccatacaggtcacggggagccaatggttcagaaaca
aatcgagtgggttctaatcatggaattaatcaaaatgtaagccagtctttgtgtcaagaa
gatgactatgaagatgataagcctaccaactatagtgaacgttactctgaagaagaacag
catgaagaagaagagagaccaacaaattatagcataaaatataatgaagagaaacatcat
gtggatcagcctattgattatagtttaaaatataccacagatattccttcttcacagaaa
cagtcattttcattctcaaagagttcgtctggacaaagtactaaaactgaacatatgtct
tcaagcagtgagaatacatccacaccttcatctaatgccaagaggcagaatcagctccat
ccaagttctgcacagagtagaagtggtcagactcaaaaggctgccacttgcaaagtttct
tctattaaccaagaaacaatacagacttattgtgtagaagatactccaatatgtttttca
agatgtagttcattatcatctttgtcatcagctgaagatgaaataggatgtggtcagacg
acacaggaagcagattctgctaataccctgcaaatagcagaaataaaagaaaagattgta
actaggtcaactgaagatcctgtgagcgaagttccagcagtgtcgcagcacactagaacc
aaatccagcagactgcagggttctaatttatcttcagaatcagccaggcacaaagctgtt
gaattttcttcaggagcgaaatctccctccaaaagtggtgctcagacacccaaaagtcca
cctgaacactatgttcaggagactccactcatgtttagcagatgtacttctgtcagttca
cttgatagttttgagagtcgttcgattgccagctccgttcagagtgaaccatgcagtgga
atggtaagtggcattataagccccagtgatcttccagatagccctggacaaaccatgcca
ccaagcagaagtaaaacccctccaccacctcctcaaacagctcaaaccaagcgagaagta
cctaaaaataaagcacccactgctgaaaagagagagagtggacctaagcaagctgcagta
aatgctgcagttcagagggtccaggttcttccagatgctgatactttattacattttgcc
acagaaagtactccagatggattttcttgttcatccagcctgagtgctctgagcctggat
gagccgtttatacagaaagatgtggaattaagaataatgcctccagttcaggaaaatgac
aatgggaatgaaacagaatcagagcagcctaaagaatcaaatgaaaaccaagagaaagag
gcagaaaaaactattgattctgaaaaggacctattagatgattcagatgatgatgatatt
gaaatactagaagaatgtattatttctgccatgccaacaaagtcatcacgtaaagcaaaa
aagccagcccagactgcttcaaaattacctccacctgtggcaaggaaaccaagtcagctg
cctgtgtacaaacttctaccatcacaaaacaggttgcaaccccaaaagcatgttagtttt
acaccgggagatgatatgccacgggtgtattgtgtagaagggacacctataaacttttcc
acagctacatctctaagtgatctaacaatcgaatcccctccaaatgagttagctgttgga
gaaggagttagaggaggggcacagtcaggtgaatttgaaaaacgagataccattcctaca
gaaggcagaagtacagatgaggctcaaggaggaaaaacctcatctgtaaccatacctgaa
ttggatgacaataaagcagaggaaggtgatattcttgcagaatgcattaattccgctatg
cccaaagggaaaagtcacaagcctttccgtgtgaaaaagataatggaccaggtccagcaa
gcatctgcgtcttcatctgcacccaacaaaaatcagttagatggtaagaaaaagaaacca
acttcaccagtaaaacctataccacaaaatactgaatataggacacgtgtaagaaaaaat
gcagactcaaaaaataatttaaatgctgagagagttttcccagacaacaaagattcaaag
aaacagaatttgaaaaataattccaaggacttcaatgataaggtcccaaataatgaagat
agagtcagaggaagttttgcttttgattcacctcatcattacacacctattgaaggaact
ccttactgtttttcacgaaatgattctttgagttctctagattttgatgatgatgatgtt
gacctttccagggaaaaggctgaattaagaaaggcaaaagaaaataaggaatcagaagct
aaagttaccagccacacagaactaacctccaaccaacaatcagctaataagacacaagct
attgcaaagcagccaataaatcgaggtcagcctaaacccatacttcagaaacaatccact
tttccccagtcatccaaagacataccagacagaggggcagcaactgatgaaaagttacag
aattttgctattgaaaatactccagtttgcttttctcataattcctctctgagttctctc
agtgacattgaccaagaaaacaacaacaataaagaaaatgaacctgtcaaagagactgaa
ccccctgactcacagggagaaccaagtaaacctcaagcatcaggctatgctcctaaatcg
tttcatgttgaagataccccagtttgtttctcaagaaacagttctctcagttctcttagt
attgactctgaagatgacctgttgcaggaatgtataagctccgcaatgccaaaaaagaaa
aagccttcaagactcaagggtgataatgaaaaacatagtcccagaaatatgggtggcata
ttagctgaagatctgacacttgatttgaaagatatacagagaccagattcagaacatggt
ctatcccctgattcagaaaattttgattggaaagctattcaggaaggtgcaaattccata
gtaagtagtttacatcaagctgctgctgctgcatgtttatctagacaagcttcatctgat
tcagattccatcctttccctgaaatcaggaatctctctgggatcaccatttcatcttaca
cctgatcaagaagaaaaaccctttacaagtaataaaggcccacgaattctaaaaccaggg
gagaaaagtacattggaaactaaaaagatagaatctgaaagtaaaggaatcaaaggagga
aaaaaagtttataaaagtttgattactggaaaagttcgatctaattcagaaatttcaggc
caaatgaaacagccccttcaagcaaacatgccttcaatctctcgaggcaggacaatgatt
catattccaggagttcgaaatagctcctcaagtacaagtcctgtttctaaaaaaggccca
ccccttaagactccagcctccaaaagccctagtgaaggtcaaacggccaccacttctcct
agaggagccaagccatctgtaaaatcagaattaagccctgttgccagacagacatcccaa
ataggtgggtcaagtaaagcaccttctagatcaggatctagagattcaaccccttcaaga
cctgcccagcaaccattaagtagacctatgcagtctcctggccgaaactcaatttcccct
ggtagaaatggaataagtcctcctaacaaattatctcaacttccaaggacatcatcccct
agtactgcttcaactaagtcctcaggttctggaaaaatgtcatatacatctccaggtaga
cagatgagccaacagaaccttaccaaacaaacaggtttatccaagaatgccagtagtatt
ccaagaagtgagtctgcctccaaaggactaaatcagatgaataatggtaatggagccaat
aaaaaggtagaactttctagaatgtcttcaactaaatcaagtggaagtgaatctgataga
tcagaaagacctgtattagtacgccagtcaactttcatcaaagaagctccaagcccaacc
ttaagaagaaaattggaggaatctgcttcatttgaatctctttctccatcgtctagacca
gcttctcccactaggtcccaggcacaaactccagttttaagtccttcccttcctgatatg
tctctatccacacattcatctgttcaggctggtggatggcgaaaactcccacctaatctc
agtcccactatagagtataatgatggaagaccagcaaagcgccatgatattgcacggtct
cattctgaaagtccttctagacttccaatcaataggtcaggaacctggaaacgtgagcac
agcaaacattcatcatcccttcctcgagtaagcacttggagaagaactggaagttcatct
tcaattctttctgcctcatcagaatccagtgaaaaagcaaaaagtgaggatgaaaaacat
gtgaactctatttcaggaaccaaacaaagtaaagaaaaccaagtatctgcaaaaggaaca
tggagaaaaataaaagaaaatgaaatttctcccacaaatagtacttctcagacggtttcc
tcaggtgctacaaatggtgctgaatcaaagactctaatttatcaaatggcacctgctgtt
tctaaaacagaggatgtttgggtgagaattgaggactgtcccattaacaatcctagatct
ggaagatctcccacaggtaatactcccccggtgattgacagtgtttcagaaaagggaaat
ccaaacattaaagattcaaaagataatcaggcaaaacaaaatgtgggtaatggcagtgtt
cccatgcgtaccgtgggtttggaaaatcgcctgaactcctttattcaggtagatgcccct
gaccaaaaaggaactgagacaaaaccaggacaaaataatcctgtccctgtatcagagact
aatgaaagttctatagtggaacgtaccccattcagttctagcagctcaagcaaacacagt
tcacctagtgggactgttgctgccagagtgactccttttaattacaacccaagccctagg
aaaagcagcgcagatagcacttcagctcggccatctcagatcccaactccagtgaataac
aacacaaagaagcgagattccaaaactgacagcacagaatccagtggaacccaaagtcct
aagcgccattctgggtcttaccttgtgacatccgtttaa

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (16)   
   RefSeq(pep) (16)   
DNA sequence (16)   
   RefSeq(nuc) (16)   
Protein domain (17)   
   Pfam (17)   
All databases (51)   

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