KEGG   Pan troglodytes (chimpanzee): 450161
Entry
450161            CDS       T01005                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr01522  Endocrine resistance
ptr04010  MAPK signaling pathway
ptr04015  Rap1 signaling pathway
ptr04068  FoxO signaling pathway
ptr04071  Sphingolipid signaling pathway
ptr04114  Oocyte meiosis
ptr04148  Efferocytosis
ptr04218  Cellular senescence
ptr04261  Adrenergic signaling in cardiomyocytes
ptr04370  VEGF signaling pathway
ptr04380  Osteoclast differentiation
ptr04517  IgSF CAM signaling
ptr04519  Cadherin signaling
ptr04550  Signaling pathways regulating pluripotency of stem cells
ptr04611  Platelet activation
ptr04613  Neutrophil extracellular trap formation
ptr04620  Toll-like receptor signaling pathway
ptr04621  NOD-like receptor signaling pathway
ptr04622  RIG-I-like receptor signaling pathway
ptr04625  C-type lectin receptor signaling pathway
ptr04657  IL-17 signaling pathway
ptr04658  Th1 and Th2 cell differentiation
ptr04659  Th17 cell differentiation
ptr04660  T cell receptor signaling pathway
ptr04664  Fc epsilon RI signaling pathway
ptr04668  TNF signaling pathway
ptr04670  Leukocyte transendothelial migration
ptr04714  Thermogenesis
ptr04722  Neurotrophin signaling pathway
ptr04723  Retrograde endocannabinoid signaling
ptr04728  Dopaminergic synapse
ptr04750  Inflammatory mediator regulation of TRP channels
ptr04912  GnRH signaling pathway
ptr04914  Progesterone-mediated oocyte maturation
ptr04917  Prolactin signaling pathway
ptr04926  Relaxin signaling pathway
ptr04932  Non-alcoholic fatty liver disease
ptr04933  AGE-RAGE signaling pathway in diabetic complications
ptr04935  Growth hormone synthesis, secretion and action
ptr04936  Alcoholic liver disease
ptr05014  Amyotrophic lateral sclerosis
ptr05020  Prion disease
ptr05022  Pathways of neurodegeneration - multiple diseases
ptr05132  Salmonella infection
ptr05133  Pertussis
ptr05135  Yersinia infection
ptr05140  Leishmaniasis
ptr05142  Chagas disease
ptr05145  Toxoplasmosis
ptr05152  Tuberculosis
ptr05161  Hepatitis B
ptr05163  Human cytomegalovirus infection
ptr05167  Kaposi sarcoma-associated herpesvirus infection
ptr05169  Epstein-Barr virus infection
ptr05170  Human immunodeficiency virus 1 infection
ptr05171  Coronavirus disease
ptr05205  Proteoglycans in cancer
ptr05208  Chemical carcinogenesis - reactive oxygen species
ptr05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ptr05415  Diabetic cardiomyopathy
ptr05417  Lipid and atherosclerosis
ptr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    450161 (MAPK14)
   04015 Rap1 signaling pathway
    450161 (MAPK14)
   04370 VEGF signaling pathway
    450161 (MAPK14)
   04668 TNF signaling pathway
    450161 (MAPK14)
   04068 FoxO signaling pathway
    450161 (MAPK14)
   04071 Sphingolipid signaling pathway
    450161 (MAPK14)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    450161 (MAPK14)
   04519 Cadherin signaling
    450161 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    450161 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    450161 (MAPK14)
   04218 Cellular senescence
    450161 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    450161 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    450161 (MAPK14)
   04613 Neutrophil extracellular trap formation
    450161 (MAPK14)
   04620 Toll-like receptor signaling pathway
    450161 (MAPK14)
   04621 NOD-like receptor signaling pathway
    450161 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    450161 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    450161 (MAPK14)
   04660 T cell receptor signaling pathway
    450161 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    450161 (MAPK14)
   04659 Th17 cell differentiation
    450161 (MAPK14)
   04657 IL-17 signaling pathway
    450161 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    450161 (MAPK14)
   04670 Leukocyte transendothelial migration
    450161 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    450161 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    450161 (MAPK14)
   04917 Prolactin signaling pathway
    450161 (MAPK14)
   04926 Relaxin signaling pathway
    450161 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    450161 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    450161 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    450161 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    450161 (MAPK14)
   04722 Neurotrophin signaling pathway
    450161 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    450161 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    450161 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    450161 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    450161 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    450161 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    450161 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    450161 (MAPK14)
   05161 Hepatitis B
    450161 (MAPK14)
   05171 Coronavirus disease
    450161 (MAPK14)
   05163 Human cytomegalovirus infection
    450161 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    450161 (MAPK14)
   05169 Epstein-Barr virus infection
    450161 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    450161 (MAPK14)
   05135 Yersinia infection
    450161 (MAPK14)
   05133 Pertussis
    450161 (MAPK14)
   05152 Tuberculosis
    450161 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    450161 (MAPK14)
   05140 Leishmaniasis
    450161 (MAPK14)
   05142 Chagas disease
    450161 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    450161 (MAPK14)
   05020 Prion disease
    450161 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    450161 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    450161 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    450161 (MAPK14)
   05415 Diabetic cardiomyopathy
    450161 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    450161 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    450161 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    450161 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    450161 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ptr01001]
    450161 (MAPK14)
Enzymes [BR:ptr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     450161 (MAPK14)
Protein kinases [BR:ptr01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   450161 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 450161
NCBI-ProteinID: NP_001009065
Ensembl: ENSPTRG00000018097
VGNC: 7197
UniProt: Q95NE7 K7BNX5
Position
5:41897573..41980466
AA seq 360 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG
TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctcaggagaggcccacgttctaccggcaggagctgaacaagacaatctgggaggtg
cccgagcgttaccagaacctgtctccagtgggctctggcgcctatggctctgtgtgtgct
gcttttgacacaaaaacggggttacgtgtggcagtgaagaagctctccagaccatttcag
tccatcattcatgcaaaaagaacctacagagaactgcggttacttaaacatatgaaacat
gaaaatgtgattggtctgttggacgtttttacacctgcaaggtctctggaggaattcaat
gatgtgtatctggtgacccatctcatgggggcagatctgaacaacattgtgaaatgtcag
aagcttacagatgaccatgttcagttccttatctaccaaattctccgaggtctaaagtat
atacattcagctgacataattcacagggacctaaaacctagtaatctagctgtgaatgaa
gactgtgagctgaagattctggattttggactggctcggcacacagatgatgaaatgaca
ggctacgtggccactaggtggtacagggctcctgagatcatgctgaactggatgcattac
aaccagacagttgatatttggtcagtgggatgcataatggccgagctgttgactggaaga
acattgtttcctggtacagaccatattaaccagcttcagcagattatgcgtctgacagga
acaccccccgcttatctcattaacaggatgccaagccatgaggcaagaaactatattcag
tctttgactcagatgccaaagatgaactttgcgaatgtatttattggtgccaatccgctg
gctgtcgacttgctggagaagatgcttgtattggactcagataagagaattacagcggcc
caagcccttgcacatgcctactttgctcagtaccacgatcctgatgatgaaccagtggcc
gatccttatgatcagtcctttgaaagcagggacctccttatagatgagtggaaaagcctg
acctatgatgaagtcatcagctttgtgccaccaccccttgaccaagaagagatggagtcc
tga

  All links  
Gene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (25)   
   RefSeq(nuc) (5)   
   GenBank (10)   
   EMBL (10)   
Protein domain (6)   
   Pfam (6)   
All databases (44)   

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