KEGG   Pan troglodytes (chimpanzee): 451056
Entry
451056            CDS       T01005                                 
Symbol
ABCC8
Name
(RefSeq) ATP-binding cassette sub-family C member 8 isoform X2
  KO
K05032  ATP-binding cassette subfamily C (CFTR/MRP) member 8
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr02010  ABC transporters
ptr04911  Insulin secretion
ptr04930  Type II diabetes mellitus
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    451056 (ABCC8)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    451056 (ABCC8)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    451056 (ABCC8)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ptr02000]
    451056 (ABCC8)
Transporters [BR:ptr02000]
 ABC transporters, eukaryotic type
  ABCC (CFTR/MRP) subfamily
   ABCC8, 9 subgroups
    451056 (ABCC8)
SSDB
Motif
Pfam: ABC_membrane ABC_tran SMC_N ABC_ATPase AAA_29 ATPase AAA_25 nSTAND1 RsgA_GTPase AAA_23 TraD_N
Other DBs
NCBI-GeneID: 451056
NCBI-ProteinID: XP_016776002
Ensembl: ENSPTRG00000003403
VGNC: 11253
Position
9:complement(21452506..21536435)
AA seq 1603 aa
MPLAFCGSENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHI
HHSTWLHFPGHNLRWILTFMLLFVLVCEIAEGILSDGVTESHHLHLYMPAGMAFMAAVTS
VVYYHNIETSNFPKLLIALLVYWTLAFITKTIKFVKFLDHAIGFSQLRFCLTGLLVILYG
MLLLVEVNVIRVRRYIFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTA
HKKPIDLRAIGKLPIAMRALTNYQRLCEAFDAQRKDIQGTQGARAIWQALSHAFGRRLVL
SSTFRILADLLGFAGPLCIFGIVDHLGKENDVFQPKTQFLGVYFVSSQEFLANAYVLAVL
LFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNLV
AIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKL
SQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFRTRVETTRRKEMTSLRAFAIYTS
ISIFMNTAIPIAAVLITFVGHVSFFKEADFSPSVAFASLSLFHILVTPLFLLSSVVRSTV
KALVSVQKLSEFLSSAEIREEQCAPHEPTPQGPASKYQAVEEGLPSLHSSQPSGSSPPNH
PQPLRVVNRKRPAREDCRGLTGPLQSLVPSADGDADNCCVQIMGGYFTWTPDGIPTLSNI
TIRIPRGQLTMIVGQVGCGKSSLLLAALGEMQKVSGAVFWSSSLPDSEIGEDPSPERETA
TDLDIRKRGPVAYASQKPWLLNATVEENIIFESPFNKQRYKMVIEACSLQPDIDILPHGD
QTQIGERGINLSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRD
DKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQEL
EKETVTERKATEPPKGLSRAMSSRDGLLQDEEEEEEEAAESEEDDNLSSVLHQRAEIPWR
ACAKYLSSAGILLLSLLVFSQLLKHMVLVAIDYWLAKWTDSALTLTPAARNCSLSQECTL
DQTVYAMVFTVLCSLGIVLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLG
SILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALAVISYVTPVFLVALLPLAIVCYFIQ
KYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASL
FLTAANRWLEVRMEYIGACVVLIAAVTSISNSLHRELSAGLVGLGLTYALMVSNYLNWMV
RNLADMELQLGAVKRIHGLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLK
PVLKHVNALISPGQKIGICGRTGSGKSSFSLAFFRMVDTFEGHIIIDGIDIAKLPLHTLR
SRLSIILQDPVLFSGTIRFNLDPERKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGG
ENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHR
VHTILSADLVIVLKRGAILEFDKPEKLLSRKDSVFASFVRADK
NT seq 4812 nt   +upstreamnt  +downstreamnt
atgcccctggccttctgcggcagcgagaaccactcggccgcctaccgggtggaccagggc
gtcctcaacaacggctgctttgtggacgcgctcaacgtggtgccgcacgtcttcctactc
ttcatcaccttccccatcctcttcattggatggggaagtcagagctccaaggtgcacatc
caccacagcacatggcttcatttccctgggcacaacctgcggtggatcctgaccttcatg
ctgctcttcgtcctggtgtgtgagattgcggagggcatcctgtctgatggggtgaccgaa
tcccaccatctgcacctgtacatgccagccgggatggcgttcatggctgctgtcacctcc
gtggtctactatcacaacatcgagacttccaacttccccaagctgctaattgccctgctg
gtgtattggaccctggccttcatcaccaagaccatcaagtttgtcaagttcttggaccac
gccatcggcttctcgcagctacgcttctgcctcacagggctgctggtgatcctctatggg
atgctgctcctcgtggaggtcaatgtcatcagggtgaggagatacatcttcttcaagaca
ccgagggaggtgaagcctcccgaggacctgcaagacctgggggtacgcttcctgcagccc
ttcgtgaatctgctgtccaaaggcacctactggtggatgaacgccttcatcaagactgcc
cacaagaagcccattgacttgcgagccatcgggaagctgcccatcgccatgagggccctc
accaactaccaacggctctgcgaggcctttgacgcccagcggaaggacattcagggcact
caaggtgcccgggccatctggcaggcactcagccatgccttcgggaggcgcctggtcctc
agcagcactttccgcatcttggccgacctgctgggcttcgccgggccactgtgcatcttt
gggatcgtggaccaccttgggaaggagaacgacgtcttccagcccaagacacaatttctc
ggggtttactttgtctcatcccaagagttccttgccaatgcctacgtcttagccgtgctt
ctgttccttgccctcctactgcaaaggacatttctgcaagcatcctactatgtggccatt
gaaactggaattaacttgagaggagcaatacagaccaagatttacaataaaattatgcac
ctgtccacctccaacctgtccatgggagaaatgactgctggacagatctgtaatctggtt
gccatcgacaccaatcagctcatgtggtttttcttcttgtgcccaaacctctgggctatg
ccagtacagatcattgtgggtgtgattctcctctactacatactcggagtcagtgcctta
attggagcagctgtcatcattctactggctcctgtccagtacttcgtggccaccaagctg
tctcaggcccagcggagcacactggagtattccaatgagcggctgaagcagaccaacgag
atgctccgcggcatcaagctgctgaagctgtacgcctgggagaacatcttccgcacgcgg
gtggagacgacccgcaggaaggagatgaccagcctcagggcctttgccatctatacctcc
atctccattttcatgaacacggccatccccattgcagctgtcctcataactttcgtgggc
catgtcagcttcttcaaagaggccgacttctcgccctccgtggcctttgcctccctctcc
ctcttccatatcttggtcacaccgctgttcctgctgtccagtgtggtccgatctaccgtc
aaagctctagtgagcgtgcaaaagctaagcgagttcctgtccagtgcagagatccgtgag
gagcagtgtgccccccatgagcccacacctcagggcccagccagcaagtaccaggcggtg
gaagaggggctcccttccctacacagctcccagcccagtgggtcctcacctccaaaccac
ccccagcccctcagggttgtgaaccgcaagcgtccagcccgggaggattgtcggggcctc
accggcccactgcagagcctggtccccagtgcagatggcgatgctgacaactgctgtgtc
cagatcatgggaggctacttcacgtggaccccagatggaatccccacactgtccaacatc
accattcgtatcccccgaggccagctgactatgatcgtggggcaggtgggctgcggcaag
tcctcgctccttctagccgcactgggggagatgcagaaggtctcaggggctgtcttctgg
agcagcagccttcctgacagcgagataggagaggaccccagcccagagcgggagacagcg
accgacttggatatcaggaagagaggccctgtggcctatgcttcgcagaaaccatggctg
ctaaatgccactgtggaggagaacatcatctttgagagtcccttcaacaaacaacggtac
aagatggtcattgaagcctgctctctgcagccagacatcgacatcctgccccatggagac
cagacccagattggggaacggggcatcaacctgtctggtggtcaacgccagcgaatcagt
gtggcccgagccctctaccagcacgccaacgtcgtcttcttggatgaccccttctcagct
ctggatatccatctgagtgaccacttaatgcaggccggcatccttgagctgctccgggac
gacaagaggacagtggtcttagtgacccacaagctacagtacctgccccatgcagactgg
atcattgccatgaaggatggcaccatccagagggagggtaccctcaaggacttccagagg
tctgaatgccagctctttgagcactggaagaccctcatgaaccgacaggaccaagagctg
gagaaggagactgtcacagagagaaaagccacagagccacccaagggcctatctcgtgcc
atgtcctcgagggatggccttctgcaggatgaggaagaggaggaagaggaggcagctgag
agcgaggaggatgacaacctgtcgtccgtgctgcaccagcgtgctgagatcccatggcga
gcctgcgccaagtacctatcctctgccggcatcctgctcctgtcgttgctggtcttctca
cagctgctcaagcacatggtcctggtggccatcgactactggctggccaagtggaccgac
agcgccctgaccctgacccctgcagccaggaactgctccctcagccaggagtgcaccctc
gaccagactgtctatgccatggtgttcacggtgctctgcagcctgggcattgtgctgtgc
ctcgtcacgtctgtcactgtggagtggacagggctgaaggtggccaagagactgcaccgc
agcctgctaaaccgtatcatcctagcccccatgaggttttttgagaccacgccccttggg
agcatcctgaacagattttcatccgactgtaacaccatcgaccagcacatcccatccaca
ctggagtgcctgagccgctccaccctgctctgtgtctcagccctggccgtcatctcctat
gtcacacctgtgttcctcgtggccctcttgcccctggccatcgtgtgctacttcatccag
aagtacttccgggtggcgtccagggacctgcagcagctggatgacaccacccagcttcca
cttctctcacactttgccgaaaccgtggaagggctcaccaccatccgggccttcaggtat
gaggcccggttccagcagaagcttctcgaatacacagactccaacaacattgcttccctc
ttcctcacagctgccaacagatggctggaagtccgaatggagtacattggtgcatgtgtg
gtgctcatcgcagcggtgacctccatctccaactccctgcacagggagctctctgctggc
ctggtgggtctgggcctcacctacgccctaatggtctccaactacctcaactggatggtg
aggaacctcgcagacatggagctccagctgggggctgtgaagcgcatccatgggctcctg
aaaaccgaggcagagagctacgaggggctcctggcaccatcgctgatcccaaagaactgg
ccagaccaagggaagatccagatccagaacctgagcgtgcgctacgacagctccctgaag
ccggtgctgaagcacgtcaacgccctcatctcccctggacagaagatcgggatctgcggc
cgcaccggcagtgggaagtcctccttctctcttgccttcttccgcatggtggacacgttc
gaagggcacatcatcattgatggcattgacatcgccaaactgccgctgcacaccctgcgc
tcacgcctctccatcatcctgcaggaccccgtcctcttcagcggcaccatccgatttaac
ctggaccctgagaggaagtgctcagatagcacactgtgggaggccctggaaatcgcccag
ctgaagctggtggtgaaggcactgccaggaggcctcgatgccatcatcacagaaggcggg
gagaatttcagccaggggcagaggcagctgttctgcctggctcgggccttcgtgaggaag
accagcatcttcatcatggacgaggccacggcttccattgacatggccacggaaaacatc
ctccaaaaggtggtgatgacagccttcgcagaccgcactgtggtcaccatcgcgcatcga
gtgcacaccatcctgagtgcagacctggtgatcgtcctgaagcggggtgccatccttgag
ttcgataagccagagaagctgctcagccggaaggacagcgtcttcgcctccttcgtccgt
gcagacaagtga

  All links  
Gene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (10)   
   RefSeq(pep) (10)   
DNA sequence (11)   
   RefSeq(nuc) (11)   
Protein domain (11)   
   Pfam (11)   
All databases (37)   

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