KEGG   Pan troglodytes (chimpanzee): 740202
Entry
740202            CDS       T01005                                 
Symbol
PDGFA
Name
(RefSeq) platelet-derived growth factor subunit A isoform X2
  KO
K04359  platelet-derived growth factor subunit A
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr01521  EGFR tyrosine kinase inhibitor resistance
ptr04010  MAPK signaling pathway
ptr04014  Ras signaling pathway
ptr04015  Rap1 signaling pathway
ptr04020  Calcium signaling pathway
ptr04072  Phospholipase D signaling pathway
ptr04151  PI3K-Akt signaling pathway
ptr04510  Focal adhesion
ptr04518  Integrin signaling
ptr04540  Gap junction
ptr04630  JAK-STAT signaling pathway
ptr04810  Regulation of actin cytoskeleton
ptr05200  Pathways in cancer
ptr05202  Transcriptional misregulation in cancer
ptr05206  MicroRNAs in cancer
ptr05214  Glioma
ptr05215  Prostate cancer
ptr05218  Melanoma
ptr05231  Choline metabolism in cancer
ptr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    740202 (PDGFA)
   04014 Ras signaling pathway
    740202 (PDGFA)
   04015 Rap1 signaling pathway
    740202 (PDGFA)
   04630 JAK-STAT signaling pathway
    740202 (PDGFA)
   04020 Calcium signaling pathway
    740202 (PDGFA)
   04072 Phospholipase D signaling pathway
    740202 (PDGFA)
   04151 PI3K-Akt signaling pathway
    740202 (PDGFA)
  09133 Signaling molecules and interaction
   04518 Integrin signaling
    740202 (PDGFA)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    740202 (PDGFA)
   04540 Gap junction
    740202 (PDGFA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    740202 (PDGFA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    740202 (PDGFA)
   05202 Transcriptional misregulation in cancer
    740202 (PDGFA)
   05206 MicroRNAs in cancer
    740202 (PDGFA)
   05231 Choline metabolism in cancer
    740202 (PDGFA)
  09162 Cancer: specific types
   05214 Glioma
    740202 (PDGFA)
   05218 Melanoma
    740202 (PDGFA)
   05215 Prostate cancer
    740202 (PDGFA)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    740202 (PDGFA)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    740202 (PDGFA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ptr04052]
    740202 (PDGFA)
   00536 Glycosaminoglycan binding proteins [BR:ptr00536]
    740202 (PDGFA)
Cytokines and neuropeptides [BR:ptr04052]
 Cytokines
  Growth factors (RTK binding)
   740202 (PDGFA)
Glycosaminoglycan binding proteins [BR:ptr00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   740202 (PDGFA)
SSDB
Motif
Pfam: PDGF_N PDGF HHH_XRCC3_RpoA KH_PARP14_8
Other DBs
NCBI-GeneID: 740202
NCBI-ProteinID: XP_016801588
Ensembl: ENSPTRG00000043435
Position
6:complement(6415702..6438553)
AA seq 249 aa
MPQASDPGRGRVAAARRPAGAPAPRPRLSAEQPAPRDAMRTLACLLLLGCGYLAHVLAEE
AEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLDTSLRVHGVHATKHAPEKRPLPI
RRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQP
SRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECTCATTSLNPDYREEDTGRPRESGKK
RKRKRLKPT
NT seq 750 nt   +upstreamnt  +downstreamnt
atgccccaggcttcggatcctgggcgggggcgcgtggcagccgccaggagaccggctgga
gcgcccgccccgcggcctcgcctctccgccgagcagccagcgcctcgggacgcgatgagg
accttggcttgcctgctgctcctcggctgcggatacctcgcccatgttctggccgaggaa
gccgagatcccccgcgaggtgatcgagaggctggcccgcagtcagatccacagcatccgg
gacctccagcgactcctggagatagactccgtagggagtgaggattctttggacaccagc
ctgagagttcacggggtccacgccactaagcatgcgcccgagaagcggcccctgcccatt
cgaaggaagagaagcatcgaggaagctgtccccgctgtctgcaagaccaggacggtcatt
tacgagattcctcggagtcaggtcgaccccacatccgccaacttcctgatctggcccccg
tgcgtggaggtgaaacgctgcaccggctgctgcaacacgagcagtgtcaagtgccagccc
tcccgtgtccaccaccgcagcgtcaaggtggccaaggtggaatacgtcaggaagaagcca
aaattaaaagaagtccaggtgaggttagaggagcatttggagtgcacctgcgcgaccacc
agcctgaatccggattatcgggaagaggacacgggaaggcctagggagtcaggtaaaaaa
cggaaaagaaaaaggttaaaacccacctaa

  All links  
Gene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (10)   
   RefSeq(pep) (10)   
DNA sequence (16)   
   RefSeq(nuc) (10)   
   GenBank (3)   
   EMBL (3)   
Protein domain (4)   
   Pfam (4)   
All databases (34)   

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