KEGG   Prionailurus viverrinus (fishing cat): 125167322
Entry
125167322         CDS       T09889                                 
Symbol
PLCB2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
pviv  Prionailurus viverrinus (fishing cat)
Pathway
pviv00562  Inositol phosphate metabolism
pviv01100  Metabolic pathways
pviv04015  Rap1 signaling pathway
pviv04020  Calcium signaling pathway
pviv04022  cGMP-PKG signaling pathway
pviv04062  Chemokine signaling pathway
pviv04070  Phosphatidylinositol signaling system
pviv04071  Sphingolipid signaling pathway
pviv04072  Phospholipase D signaling pathway
pviv04081  Hormone signaling
pviv04082  Neuroactive ligand signaling
pviv04261  Adrenergic signaling in cardiomyocytes
pviv04270  Vascular smooth muscle contraction
pviv04310  Wnt signaling pathway
pviv04371  Apelin signaling pathway
pviv04540  Gap junction
pviv04611  Platelet activation
pviv04613  Neutrophil extracellular trap formation
pviv04621  NOD-like receptor signaling pathway
pviv04713  Circadian entrainment
pviv04720  Long-term potentiation
pviv04723  Retrograde endocannabinoid signaling
pviv04724  Glutamatergic synapse
pviv04725  Cholinergic synapse
pviv04726  Serotonergic synapse
pviv04728  Dopaminergic synapse
pviv04730  Long-term depression
pviv04742  Taste transduction
pviv04750  Inflammatory mediator regulation of TRP channels
pviv04911  Insulin secretion
pviv04912  GnRH signaling pathway
pviv04915  Estrogen signaling pathway
pviv04916  Melanogenesis
pviv04918  Thyroid hormone synthesis
pviv04919  Thyroid hormone signaling pathway
pviv04921  Oxytocin signaling pathway
pviv04922  Glucagon signaling pathway
pviv04924  Renin secretion
pviv04925  Aldosterone synthesis and secretion
pviv04926  Relaxin signaling pathway
pviv04927  Cortisol synthesis and secretion
pviv04928  Parathyroid hormone synthesis, secretion and action
pviv04929  GnRH secretion
pviv04933  AGE-RAGE signaling pathway in diabetic complications
pviv04934  Cushing syndrome
pviv04935  Growth hormone synthesis, secretion and action
pviv04961  Endocrine and other factor-regulated calcium reabsorption
pviv04970  Salivary secretion
pviv04971  Gastric acid secretion
pviv04972  Pancreatic secretion
pviv04973  Carbohydrate digestion and absorption
pviv05010  Alzheimer disease
pviv05016  Huntington disease
pviv05017  Spinocerebellar ataxia
pviv05022  Pathways of neurodegeneration - multiple diseases
pviv05142  Chagas disease
pviv05143  African trypanosomiasis
pviv05146  Amoebiasis
pviv05163  Human cytomegalovirus infection
pviv05200  Pathways in cancer
pviv05415  Diabetic cardiomyopathy
pviv05417  Lipid and atherosclerosis
Module
pviv_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:pviv00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    125167322 (PLCB2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    125167322 (PLCB2)
   04310 Wnt signaling pathway
    125167322 (PLCB2)
   04371 Apelin signaling pathway
    125167322 (PLCB2)
   04020 Calcium signaling pathway
    125167322 (PLCB2)
   04070 Phosphatidylinositol signaling system
    125167322 (PLCB2)
   04072 Phospholipase D signaling pathway
    125167322 (PLCB2)
   04071 Sphingolipid signaling pathway
    125167322 (PLCB2)
   04022 cGMP-PKG signaling pathway
    125167322 (PLCB2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    125167322 (PLCB2)
   04081 Hormone signaling
    125167322 (PLCB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    125167322 (PLCB2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    125167322 (PLCB2)
   04613 Neutrophil extracellular trap formation
    125167322 (PLCB2)
   04621 NOD-like receptor signaling pathway
    125167322 (PLCB2)
   04062 Chemokine signaling pathway
    125167322 (PLCB2)
  09152 Endocrine system
   04911 Insulin secretion
    125167322 (PLCB2)
   04922 Glucagon signaling pathway
    125167322 (PLCB2)
   04929 GnRH secretion
    125167322 (PLCB2)
   04912 GnRH signaling pathway
    125167322 (PLCB2)
   04915 Estrogen signaling pathway
    125167322 (PLCB2)
   04921 Oxytocin signaling pathway
    125167322 (PLCB2)
   04926 Relaxin signaling pathway
    125167322 (PLCB2)
   04935 Growth hormone synthesis, secretion and action
    125167322 (PLCB2)
   04918 Thyroid hormone synthesis
    125167322 (PLCB2)
   04919 Thyroid hormone signaling pathway
    125167322 (PLCB2)
   04928 Parathyroid hormone synthesis, secretion and action
    125167322 (PLCB2)
   04916 Melanogenesis
    125167322 (PLCB2)
   04924 Renin secretion
    125167322 (PLCB2)
   04925 Aldosterone synthesis and secretion
    125167322 (PLCB2)
   04927 Cortisol synthesis and secretion
    125167322 (PLCB2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    125167322 (PLCB2)
   04270 Vascular smooth muscle contraction
    125167322 (PLCB2)
  09154 Digestive system
   04970 Salivary secretion
    125167322 (PLCB2)
   04971 Gastric acid secretion
    125167322 (PLCB2)
   04972 Pancreatic secretion
    125167322 (PLCB2)
   04973 Carbohydrate digestion and absorption
    125167322 (PLCB2)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    125167322 (PLCB2)
  09156 Nervous system
   04724 Glutamatergic synapse
    125167322 (PLCB2)
   04725 Cholinergic synapse
    125167322 (PLCB2)
   04728 Dopaminergic synapse
    125167322 (PLCB2)
   04726 Serotonergic synapse
    125167322 (PLCB2)
   04720 Long-term potentiation
    125167322 (PLCB2)
   04730 Long-term depression
    125167322 (PLCB2)
   04723 Retrograde endocannabinoid signaling
    125167322 (PLCB2)
  09157 Sensory system
   04742 Taste transduction
    125167322 (PLCB2)
   04750 Inflammatory mediator regulation of TRP channels
    125167322 (PLCB2)
  09159 Environmental adaptation
   04713 Circadian entrainment
    125167322 (PLCB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    125167322 (PLCB2)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    125167322 (PLCB2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    125167322 (PLCB2)
   05142 Chagas disease
    125167322 (PLCB2)
   05143 African trypanosomiasis
    125167322 (PLCB2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    125167322 (PLCB2)
   05016 Huntington disease
    125167322 (PLCB2)
   05017 Spinocerebellar ataxia
    125167322 (PLCB2)
   05022 Pathways of neurodegeneration - multiple diseases
    125167322 (PLCB2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    125167322 (PLCB2)
   05415 Diabetic cardiomyopathy
    125167322 (PLCB2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    125167322 (PLCB2)
   04934 Cushing syndrome
    125167322 (PLCB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pviv04131]
    125167322 (PLCB2)
Enzymes [BR:pviv01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     125167322 (PLCB2)
Membrane trafficking [BR:pviv04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    125167322 (PLCB2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    125167322 (PLCB2)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2 COG6_C Sde182_NH-like Peptidase_S46
Other DBs
NCBI-GeneID: 125167322
NCBI-ProteinID: XP_047717248
Position
B3:58192995..58213080
AA seq 1193 aa
MSLLNPVLLPAKVKAYLSQGERFIKWDDETTIASPVILRVDPKGYYLYWTYQSKEIEFLD
ITSIRDTRFGKFAKIPKSQKLRDVFNMDFPENNFLLKTLTVVSGPDMVDLTFHNFVSYKE
NVGQNWAEDVLALVKHPLTANASRSTFLDKILVKLKMQLNPEGKIPVKNFFQMFPADRKR
VEAALSSCHLPKGKNDAINPEDFPESVYKSFLMSLCPRPEIDEIFTSYHAKAKPYMTKEH
LTKFINQKQRDSRLNSLLFPPARPDQVRGLIDKYEPSAINVQRGQLSPEGMVWFLCGPEN
SVLAQDKLLLYQDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLAGCRCVELDC
WKGRPPDEEPIITHGFTMTTDIYFKEAIEAIAESAFKTSPYPVILSFENHVDSPRQQAKM
AEYCRTMFGDMLLTEPLEKFPLKPGIPLPSPEDLRGKILIKNKKNQFSGPASPSKEPGGE
AEGDCPPSASVGEGTAWAGEEGTEPEEEEVEEEEESGSLNEEEIKKMQSDEGTAGLEVTA
YEEMSSLVNYIQPTKFISFEFSAQKNRSYVISSFTELKAYDLLSKASVQFVDYNKRQMSR
IYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGYLLKHEFMR
RPDKQFNPFSVDRIDVVVATTLSITVISGQFLSERSVRTYVEVELFGLPGDPKRRYRTKL
SPSANSINPVWKEEPFVFEKILMPELASLRVAVMEEGNRFLGHRIIPINALNSGYHHLCL
HSESNMPLTMPALFVFLEMKDYVPDTWADLTVALANPIKFFSAHDKKSVKLKEAIGGLPE
KPFPPGSLVAGHVNGALAPLSNGSAAHAVALAAAGARAREEAVKEAAEPRTASLEELREL
KGVVKLQRRHEKELRDLERRGARRWEELLQRGAAQLAELGPPGPGGCGGRRLGASKGSRK
KRTPLCEEAAGAAPSEGREGPEGADARARELKDRLELELLQQGEERYECILKRKEQHVAE
QIAKMMELAREKQAVELKTLKETLETDTKEMKKKLEAKRIERIQAMVKVTSDKMAQERLK
REINNSHIQEVVQAIKQMTENLEKHQEKLEEKQAACLEQIREMEKQFQQEALAEYEAKMK
GLEAEVKESVRTCLRDCFPSEAKDKPERSFGAFKELCEQDPLTAKADAQESRL
NT seq 3582 nt   +upstreamnt  +downstreamnt
atgtctctgctcaaccctgtcctgcttcccgccaaggtgaaggcttatctgagccaaggg
gagcgcttcatcaaatgggacgatgaaaccacaatagcctccccggttatcctccgtgtg
gatcccaaaggctactacttatattggacataccagagtaaggagatagagtttctggat
atcaccagcatcagggatactcgctttgggaagtttgccaagatacccaagagccagaag
ctccgggatgtcttcaacatggactttcctgagaacaacttcctgctaaagacgctcact
gtggtgtctggcccggacatggtggacctcaccttccacaactttgtctcctacaaggag
aacgtgggccagaactgggctgaagatgtactggctctggtcaagcacccgctgacagcc
aatgcctctcgcagcaccttcctggacaaaatcctggtaaagctcaagatgcagctcaat
cccgaagggaagattcctgtgaagaattttttccagatgtttcctgctgaccgcaagcgg
gtggaagctgccctcagctcctgccacctccccaaaggcaagaatgatgccatcaatcct
gaggacttcccagaatccgtctacaagagtttcctcatgagcctctgtcctcggccagaa
atagatgagatcttcacttcctaccatgccaaggccaagccctacatgaccaaggagcac
ctgacgaaattcatcaaccagaaacagagggactcccgcctcaactctttgctgtttccg
cccgcccggcctgaccaagtgcggggcctcatcgacaagtacgagcccagtgcaatcaac
gtgcagaggggccagctgtcacctgagggcatggtgtggtttctctgtgggccggagaac
agtgtgctggcccaggacaagctgctactctaccaagacatgacacagccactcaaccat
tacttcatcaactcctcacacaacacctacctgacagctggccagttctctggcctttcc
tcggcagagatgtaccgccaggtgctgctggctggctgtcgctgcgtggagctggactgc
tggaagggcaggccccctgacgaagagcccatcatcacccacggctttaccatgaccaca
gacatctatttcaaggaagcaattgaagccattgcagaaagtgcttttaagacctccccc
tatcctgtcatcctgtcatttgaaaaccatgtggactcaccccgccaacaggccaagatg
gctgagtattgccggacgatgtttggggacatgctactcacagagcccctggaaaagttc
ccactgaaaccaggcatccccctgcccagccccgaggatctccgaggcaagatcctcatc
aagaacaaaaagaaccagttttctggcccagcatcccccagcaaggagccgggtggggag
gctgagggcgactgcccacccagtgcctctgtgggtgagggcacagcgtgggctggtgaa
gaaggaacagagccggaggaggaagaggtggaagaggaggaggagtcgggaagcctgaat
gaggaagagatcaagaagatgcagtcggacgagggcacagcgggcctggaggtgacagct
tatgaggagatgtccagcctagtgaattacattcaacccaccaagttcatctcctttgag
ttctctgcccagaagaaccgaagttatgtcatctcctccttcacagagctcaaggcttac
gacctgctctccaaggcctcagtgcagtttgtggactacaacaagcgccagatgagccgc
atttaccctaagggcacccgcatggactcctccaactacatgccccagatgttctggaat
gctggttgccagatggttgccctcaacttccagacgatggacctgcccatgcagcagaac
atggcgctgtttgagttcaatgggcagagtggctacctcctcaagcatgagttcatgcgc
cggccagacaagcagttcaaccccttctcagtggaccgcatcgatgtggtggtagccacc
accctctccattacggtgatctctgggcagttcctgtcagaacgcagtgtgcgcacctat
gtcgaagtggagctgtttggccttcctggggaccccaagaggcgctatcgcaccaagctg
tcacccagtgccaactctatcaatcctgtctggaaggaggagccctttgtctttgagaag
atcttgatgcctgagctggcctccctcagggtggctgtaatggaggaaggcaacagattt
cttggacaccgcatcatccccattaatgccctgaattctggctaccaccatctgtgcctg
cacagcgagagcaacatgccccttaccatgcctgcgctttttgtcttcctggagatgaag
gactatgtacctgacacctgggcagatctcaccgtggctcttgccaatcccatcaagttc
ttcagtgcccacgataagaagtctgtgaagctcaaggaagccataggaggtctgcctgag
aaacccttcccaccggggagtctggtcgccggccacgtcaatggggcactggccccactg
agcaacgggtctgcagcccacgctgtggctcttgcagcagccggggccagggccagggag
gaggccgtgaaagaagctgcggagccacggacggccagcctggaggagctgcgggagctg
aagggcgtcgtgaagctgcagcggcggcacgagaaggagctgcgggacctggagcggcgc
ggcgcgcggcgctgggaggagctgctgcagaggggcgcggcgcagctggccgagctgggg
ccgccgggaccggggggctgcgggggccgcaggctcggcgcgagcaagggctcccgcaag
aagaggaccccgctctgcgaggaggccgccggggccgcgccgagcgagggccgcgagggc
cccgagggcgcggacgctcgcgcgagggagctgaaggaccgcctggagctggagctgctg
cagcagggcgaggagcggtacgagtgcatcctgaagcgcaaggagcagcacgtggccgag
caaatcgccaagatgatggagctggccagagagaagcaggctgtggagctgaagaccctc
aaggagaccttggagactgataccaaagagatgaagaaaaagctggaggccaagaggata
gagcggatccaggccatggtcaaagtcacctcggacaagatggctcaagaaaggctgaag
agagagattaacaactctcacattcaggaggtggtgcaagccatcaagcagatgacagag
aacctggagaagcaccaggagaagctggaggagaagcaggcagcttgcctggagcagatc
cgggagatggaaaagcagttccagcaggaggcactggcagagtacgaggccaagatgaag
ggcttggaggccgaggtgaaggagtcagtgaggacctgcctcagggactgcttcccctct
gaggccaaggacaagcctgagaggtcctttggggccttcaaggagctgtgtgagcaggac
ccactcacagcaaaggcagatgcccaggagagtcgcctctga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (8)   
   RefSeq(pep) (8)   
DNA sequence (10)   
   RefSeq(nuc) (10)   
Protein domain (10)   
   Pfam (10)   
All databases (30)   

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