KEGG T07722: 117012829

Rhinolophus ferrumequinum (greater horseshoe bat): 117012829

Entry

117012829         CDS       T07722

Symbol

TOP3A

Name

(RefSeq) DNA topoisomerase 3-alpha isoform X1

K03165

DNA topoisomerase III [EC:5.6.2.1]

Organism

rfq Rhinolophus ferrumequinum (greater horseshoe bat)

Pathway

rfq03440

Homologous recombination

rfq03460

Fanconi anemia pathway

Brite

KEGG Orthology (KO) [BR:rfq00001]
09120 Genetic Information Processing
  09124 Replication and repair
   03440 Homologous recombination
    117012829 (TOP3A)
   03460 Fanconi anemia pathway
    117012829 (TOP3A)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:rfq03032]
    117012829 (TOP3A)
   03400 DNA repair and recombination proteins [BR:rfq03400]
    117012829 (TOP3A)
Enzymes [BR:rfq01000]
5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.1  DNA topoisomerase
     117012829 (TOP3A)
DNA replication proteins [BR:rfq03032]
Eukaryotic type
  DNA Topoisomerases
   117012829 (TOP3A)
DNA repair and recombination proteins [BR:rfq03400]
Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    Bloom's syndrome complex (BTR)
     117012829 (TOP3A)
   FA (Fanconi anemia) pathway
     117012829 (TOP3A)

SSDB

Motif

Pfam:

Topoisom_bac Zn_ribbon_GRF Toprim Zn_ribbon_Top1 Zn_ribbon_GRF_2 zf-C2H2_10 Zn_ribbon_recom Lar_restr_allev

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

UniProt:

Position

21:570816..600175

AA seq 1006 aa
MIFPVARYAVRWLHRPGGQTLPPSAMEVAFRGVRKVLCVAEKNDAAKGIADLLSNGRMRR
REGLSKFNKIYEFDYHLYGQNVTMIMTSVSGHLLADDFQMRFRKWQSCNPLALFEAEIEK
YCPENFVDIKKTLERESRQCQVLVIWTDCDREGENIGFEVIHVCKAVKPTLQVLRARFSE
ITPRAVKTACENLTEPDQRVSDAVDVRRELDLRIGAAFTRFQTLRLQKIFPEVLAEQLIS
YGSCQFPTLGFVVERFKAIQAFVPEIFHKIKVTHDHRDGIVEFNWKRHRLFNHTACLVLY
QLCMEDPRATVVEVSCKAKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYI
SYPRTETNIFPKDLNLTALVEQQTSDPRWGAFARSILERGAPTPRNGHKSDQAHPPIHPT
KYTSSLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLVILARNYLDV
YPYDRWGDKTLPVYERGSRFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAE
HIETIKARMYVGLTPDRRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKK
DKSVVLRQQIQKYKQVFIEAVAKAKKLDDALSQYFGEGAEVAQQEAIYPSVPEPIKKCPQ
CNKDMVLKTKKSGGFYLSCTGFPECRSAVWFPESVLEASRDGSVCPVCQPHPVYRLKLKF
KRGSLPPTMPLEFVGCIGGCDETLREILDLRFSQGPPRACQPATQPSGYLQASQSLNRTD
GQHSHPRPPGTKQARPSTAPAQNLPPPAAAGESNSVTCNCGQDALLLTVRKEGPNQGRQF
YKCHGGSCNFFLWSDSSHPEAGRTPSSTSGPPGGSLGRPLGSGNHPSGFGRPGADRDGGT
SCLCGQPAVRLTVQKDGPNKGRQFHTCTKPRERQCGFFEWVDENMAPGTFGAPPWPGGRG
RIQGPESRSKRAQSSSSDTGSTAKKPRKCSLCHQPGHTRPFCPQYR

NT seq 3021 nt +upstreamnt +downstreamnt
atgatcttcccggtcgcccgctacgcagtccggtggctgcatcggcccggaggccagacc
ctgcccccgtccgccatggaggtggccttccgaggcgtgcggaaagtactctgtgtggcg
gagaaaaacgacgcggccaaggggatcgccgacttgctttccaacggtcgcatgaggcgg
agggaaggactttctaaattcaataagatctatgaatttgattatcatctgtacggccag
aatgttaccatgataatgacttcagtttctggacatttgctggctgatgatttccagatg
cggtttcgcaaatggcagagctgcaatccccttgccctctttgaagcagaaattgaaaag
tactgcccagagaactttgtagacatcaagaaaactctggaacgagagagtcggcagtgc
caggtcctggtgatctggaccgactgtgacagagaaggtgaaaatatcgggtttgaggtt
atccacgtgtgcaaggctgtaaagcccaccctgcaggtgctgagagcccgtttctctgag
atcacaccccgagccgttaagacagcctgtgaaaacctgactgagcctgatcagagagtg
agcgacgctgtggacgtgaggcgggagctggatctgaggatcggagctgccttcactagg
ttccagactctgaggctgcaaaagattttccccgaggtgttggcagagcagctgatcagt
tacggcagctgccagttcccaacactggggtttgtggtggagagatttaaagccattcag
gcttttgtaccagaaatcttccacaaaattaaagtaacccatgaccacagagatggcatt
gtagaatttaactggaaaaggcatcgtctctttaaccacacagcttgtcttgtcctctat
cagctatgcatggaggatcccagggcaaccgtggtggaggtcagctgtaaagcaaagagc
aagtggaggcctcaagctttggacactgtggagcttgagaagctggcttctcgaaagttg
agaataaatgctaaagaaaccatgaggattgctgaaaagctctacactcaagggtacatc
agctatccaagaactgaaacaaacattttccccaaagacttaaacctgacagcactggtg
gaacagcagacctcagatccacgttggggggcctttgcgcggagcatcctagagcggggt
gcccccacgcctcgtaacgggcacaagtctgaccaagctcaccctcccatccaccccacc
aaatacaccagcagcttacagggagatgagcagcgactctacgagtttatcgttcgccat
ttcctggcttgctgctcccaggatgctcaggggcaggagaccaccgtggagattgacatc
gctcaggaacgctttgtggcccatggcctcgtgattctggcccggaattatctggacgtg
tacccatacgaccgctggggtgacaagacccttcctgtgtatgagagaggctcccgcttt
cagcccagcactgtggagatggtggatggggagaccagtcccccccagctgctcaccgaa
gccgacctcattgccctcatggaaaagcatggcattggtactgacgccacccacgcggag
cacatcgagaccatcaaagcccggatgtacgtggggcttacgccagacaggcggtttctc
cctgggcatctgggcatgggactcgtggaaggttatgactccatgggctacgagatgtct
aagcctgacctccgggctgagctggaagccgatctgaagctgatctgtgaggggaagaag
gataaatctgtggttttaaggcagcagatccagaaatacaagcaggttttcattgaagca
gtggctaaagctaagaagttggacgacgccttgtcccagtactttggggaaggggcagag
gtggcccagcaagaagccatctacccgtcggtgccggagcctatcaagaagtgcccccaa
tgcaacaaggacatggtcctcaagacgaagaagagcggcgggttctacctcagctgcacg
ggtttcccggaatgtcgatcggccgtatggttccctgagtcggtgctggaggccagcagg
gatgggagtgtgtgtccagtgtgtcagccacaccctgtctacaggttgaagttgaagttt
aaacgtggtagccttccgccgaccatgcctctggaatttgttggctgcattggtggatgt
gatgagaccctgagggagatcttggacctaaggttttcacagggcccccccagagcttgc
cagccagccacccagccctctggctacctgcaggctagccagtccttgaacagaacagac
ggccagcacagccacccccggcctcctggcaccaagcaggccaggccctcgacagctccg
gcccagaacctaccaccgcccgctgctgctggtgaaagcaactccgtgacctgcaactgt
ggccaggatgccctgctgctcactgtccgcaaggagggtcccaaccagggccggcagttc
tataagtgccatggtggcagctgcaacttcttcctgtggtccgacagcagccatccagaa
gcaggaaggactccttcctccacatcagggcccccaggtggctcactggggcgcccactg
ggctcagggaaccacccaagtgggtttggcagacctggtgctgaccgtgatggtggcaca
tcctgcctgtgcggccagcccgctgtcagactgactgtgcagaaggatgggcccaacaag
gggcgtcagttccacacgtgcaccaagcccagagagcggcagtgtggcttctttgagtgg
gtggacgagaacatggccccagggacttttggagccccgccctggccaggaggcagagga
agaatccagggaccggagtccagaagcaagagagcccagtccagctcctcagacacaggg
tccacggccaagaaaccccggaaatgcagcctttgccaccagcctggacacacccgcccc
ttctgtcctcagtacagatga

All links

Gene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (8)   
   Pfam (8)   
All databases (18)   

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