KEGG   Rhinolophus ferrumequinum (greater horseshoe bat): 117013180
Entry
117013180         CDS       T07722                                 
Symbol
ULK2
Name
(RefSeq) serine/threonine-protein kinase ULK2 isoform X1
  KO
K08269  serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
Organism
rfq  Rhinolophus ferrumequinum (greater horseshoe bat)
Pathway
rfq04136  Autophagy - other
rfq04140  Autophagy - animal
rfq04150  mTOR signaling pathway
rfq05010  Alzheimer disease
rfq05014  Amyotrophic lateral sclerosis
rfq05016  Huntington disease
rfq05017  Spinocerebellar ataxia
rfq05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:rfq00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    117013180 (ULK2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    117013180 (ULK2)
   04136 Autophagy - other
    117013180 (ULK2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    117013180 (ULK2)
   05014 Amyotrophic lateral sclerosis
    117013180 (ULK2)
   05016 Huntington disease
    117013180 (ULK2)
   05017 Spinocerebellar ataxia
    117013180 (ULK2)
   05022 Pathways of neurodegeneration - multiple diseases
    117013180 (ULK2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rfq01001]
    117013180 (ULK2)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rfq04131]
    117013180 (ULK2)
   03029 Mitochondrial biogenesis [BR:rfq03029]
    117013180 (ULK2)
Enzymes [BR:rfq01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     117013180 (ULK2)
Protein kinases [BR:rfq01001]
 Serine/threonine kinases: Other
  ULK family [OT]
   117013180 (ULK2)
Membrane trafficking [BR:rfq04131]
 Autophagy
  Autophagosome formation proteins
   Atg1 complex
    117013180 (ULK2)
Mitochondrial biogenesis [BR:rfq03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-independent mechanism factors
    117013180 (ULK2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ATG1-like_MIT2 ATG1-like_MIT1 Kdo ABC1 RIO1 Pkinase_fungal APH Kinase-like TcdA_TcdB
Other DBs
NCBI-GeneID: 117013180
NCBI-ProteinID: XP_032945987
Ensembl: ENSRFEG00010010099
UniProt: A0A671EP64
Position
21:complement(3306733..3395827)
AA seq 1036 aa
MEVVGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKIL
KELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMR
ILHSKGIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMY
MAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRET
SPYLANLLLGLLQRNQKDRMDFETFFSHPFLEQVPIKKSCPVPVPTYTGSVSGSSCGSSP
PCRFASPPSLPDMQHIQEENLSSPPLGPPNYLQVSKDSASTSSKNSSCDTDDFVLVPHNI
SSDHSYDMPMGTAGRRASNEFLVCGGQCQPTVSPHCETTPIPVPTQIRNYQRIEQNLTST
ASSGTNLHGSPRSTVVRRSNTSPMGFLRLGSCSPAPADTVQTVGRRLSTGSSRPYSPSPL
VGTIPEQLSQCCCGHPQSHESRSRNSSGSPVPQAQSPQSFLLGARLQSTPTLTDIYQNKQ
KLRKQHSDPVCPSHAGAGYSYSPQPNRPGSLGTSPTKHMGSSPRSSDWFFKTPLPTIIGS
PTKTTAPFKIPKTQASSNLLALVPRHGPSEGQAKDGNDPRECSHCLLIQGNERQKSEQQN
KAVFGRSVSTGKLSDQQVKTPFGGHQGSTDSLNTERPMDIAPVGACGVVLAPPMGATASS
RAVLFTVGSPPHSAAAPTCTHMVLRTRTTSVGSSSSGGSLCSTSGRVCVGSPPGPCWGSS
PPGAEAAPSLRYVPYGASPPSLEGLITFEAPELPEETLMEREHTDTLRHLNVMLTFTECV
LDLTAVREASPELCTSAVSLYQIQESVVVDQISQLSKDWGRVEQLVLYMKAAQLLAASLH
LAKAQIKSGKLSPSTAVKQVVKNLNERYKFCITMCKKLTEKLNRFFSDKQRFIDEINSVT
AEKLIYNCAVEMVQSAALDEMFQQTEDIVYRYHKAALLLEGLTKILQDPADIESVHKYKS
SIERRLSALCYSTSAM
NT seq 3111 nt   +upstreamnt  +downstreamnt
atggaagtggtgggcgacttcgagtacagcaagcgggacctcgtgggacacggggccttc
gccgtggtcttccgggggcggcaccgccagaaaactgattgggaggtagccattaaaagt
attaataaaaagaacttgtcaaaatcacaaatactgcttgggaaggaaattaaaatctta
aaggaacttcagcatgaaaacattgtagcactctatgatgttcaggaattacccaactct
gtctttctggtgatggagtattgcaatggtggagacttggcagattatttgcaagctaaa
ggaactctcagtgaagatactatcagagtgtttctgcatcagattgcagctgccatgcga
attctgcacagcaaaggaataatccacagggatctcaagccacagaacatcttgttgtct
tatgccaatcgcagaaagtccagtgtcagtggtattcgcatcaaaatagcggattttggt
tttgctcgttacctacatagtaacatgatggctgcaacactgtgtgggtccccaatgtac
atggctcctgaggttattatgtctcaacattatgatgctaaggcagacttgtggagcata
ggaacagtgatatatcaatgcctagtaggaaaaccaccttttcaggccaatagtcctcaa
gacctaaggatgttttatgaaaaaaacaggagcttaatgcctagcatccccagagaaaca
tcaccttatttggctaatctccttttgggtttgcttcaaagaaaccaaaaagatagaatg
gactttgaaacattttttagccatccctttcttgagcaagttccaataaaaaaatcctgc
ccagtccctgtgcccacgtatactggctctgtgtctggaagctcctgtggcagctctcca
ccttgtcgttttgcctctccaccatcccttccagatatgcagcatattcaggaagaaaac
ttatcctccccaccactgggtcctcccaactacctacaagtgtccaaagactctgccagt
actagtagcaagaactcttcttgtgacacggatgactttgttttggttccacacaacatc
tcgtcagaccactcatatgatatgccaatgggaactgctggcagacgagcttcaaatgag
ttcttggtgtgtggagggcagtgtcagcctactgtgtcacctcattgtgaaacaacacca
attccggttcctactcagataaggaattatcaacgcatagagcagaatcttacatctact
gccagttctggcacaaatctacatggttctccaagatctacagtggtacgaaggtctaac
accagccctatgggcttcctccggttgggatcctgctccccagcgccagcagacacagta
cagacagttggacgaagactctctactggctcttccaggccttattcaccttcccctttg
gttggtaccattcctgagcaattaagtcagtgctgctgtggacatcctcagagccatgaa
tccaggagtagaaactcatcaggttctccagtgccgcaggctcagtcaccacagtctttc
ttattgggtgctagactgcagagcacccccaccctcactgacatctaccagaacaagcag
aagctcagaaagcagcactctgaccctgtgtgcccatcccacgccggggctgggtacagc
tactctcctcagcccaatcggcctggcagcctagggacctctcccaccaagcacatgggg
tcctctccacggagttctgactggttctttaaaacccctttgccaacaatcattggctct
cctactaagaccacagctcctttcaaaatccctaaaacacaagcatcttccaacctacta
gccttggttcctcgtcacgggccttctgaagggcaggctaaagatgggaatgacccacgt
gaatgctctcattgtctcctcatacaaggaaatgagaggcagaagtctgagcagcagaac
aaggcagtgtttggcagatctgtcagtactggaaaattatcagatcaacaagtaaagaca
cctttcggtggacatcagggcagcacagatagtttaaatacagaacgaccgatggatata
gcccctgtaggagcctgtggtgttgtgctggcaccccctatgggagcaacagcgagttcc
agggctgtcctattcactgtaggatctcctccacacagcgctgcggcccccacctgtacc
cacatggtccttcgaacaagaacaacctcagtgggctccagcagctcgggaggctccctg
tgctccactagtggccgcgtgtgtgtgggctccccacctggtccctgctgggggtcttct
cctccaggagcagaggcagctcctagcctgagatacgtgccttatggtgcttcacccccc
agcctagaggggctcatcacctttgaagcccctgaactgccggaggagacactgatggag
cgagaacacacagatacgttacgtcacctgaatgtgatgctgacgttcacggagtgtgtc
ctggacctgacagccgtgagggaggcgagcccagagctctgcacctctgcagtgtccttg
taccagatccaagagagtgtggttgtggaccagatcagccagctgagcaaagactggggg
cgggtggagcagctggtgttgtacatgaaagcggcacagctactggcagcatctctgcat
cttgccaaagcccaaatcaagtcggggaaactgagcccgtccacagcggtgaaacaagtt
gtcaaaaatctgaatgaacgatataaattctgcatcaccatgtgcaagaaacttacagaa
aagctgaatcgcttcttctctgacaaacagagatttattgatgaaatcaacagcgtaact
gcagagaaactcatctataattgtgctgtagaaatggttcagtctgcagccctggatgag
atgtttcagcagactgaagatattgtttatcgctatcataaggcagcccttcttttggaa
ggcctaactaagattctccaggaccctgcagatattgaaagtgtacataaatataaatct
agtattgaaagaagattgtcagcactctgctatagcacctcggccatgtga

  All links  
Gene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (11)   
   Pfam (11)   
All databases (19)   

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