KEGG   PATHWAY: rn00625
Entry
rn00625                     Pathway                                

Name
Chloroalkane and chloroalkene degradation
Class
Metabolism; Xenobiotics biodegradation and metabolism
Pathway map
rn00625  Chloroalkane and chloroalkene degradation
rn00625

Other DBs
UMBBD: tce tce2 tca atl dcm dce cpr caa
Reaction
R00603  dichloromethane chloride-lyase (adding H2O; chloride-hydrolysing; formaldehyde-forming)
R00604  Formaldehyde:NAD+ oxidoreductase
R00614  formaldehyde:formaldehyde oxidoreductase
R05233  trans-3-Chloro-2-propene-1-ol:NAD+ oxidoreductase
R05234  cis-3-chloro-2-propene-1-ol:NAD+ oxidoreductase
R05237   
R05238   
R05284  1,2-Dichloroethane halidohydrolase
R05285  2-chloroethanol:cytochrome c oxidoreductase
R05286  Chloroacetaldehyde:NAD+ oxidoreductase
R05287  Chloroacetic acid halidohydrolase
R05351   
R05367  trans-1,3-Dichloropropene chlorohydrolase
R05368  cis-1,3-Dichloropropene chlorohydrolase
R05371  trans-3-chloroacrylic acid chlorohydrolase
R05372  cis-3-chloroacrylic acid chlorohydrolase
R05380  acetaldehyde hydro-lyase
R05444   
R05496  reduced ferredoxin:acetylene oxidoreductase (ATP-hydrolysing)
R05498   
R05499   
R05500   
R05501   
R05502   
R05503   
R05842  ethylene oxide hydrolase
R06973  3-oxopropanoate carboxy-lyase
R09128  2-chloroethanol:cytochrome c oxidoreductase
R09141   
R09142   
R09143   
R09144   
R09145   
R09146   
R09147   
R09148   
R09149   
R09150   
R09151  trichloroethene,NADH:oxygen oxidoreductase (glyoxylate-forming)
R09152  trichloroethene,NADH:oxygen oxidoreductase (formate-forming)
R09154   
R09155   
R09156  chloroethane,donor:oxygen oxidoreductase (dechlorinating, acetaldehyde-forming)
R09157   
R09158   
R11897  2-hydroxyethyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming)
R11898   
R11899  2-chloro-2-hydroxyethyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming)
R11900   
R11901  chloroethylene,NADH:oxygen oxidoreductase
Compound
C00011  CO2
C00024  Acetyl-CoA
C00048  Glyoxylate
C00058  Formate
C00067  Formaldehyde
C00084  Acetaldehyde
C00160  Glycolate
C00209  Oxalate
C00222  3-Oxopropanoate
C00237  CO
C01380  Ethylene glycol
C01548  Acetylene
C02271  Dichloromethane
C06547  Ethylene
C06548  Ethylene oxide
C06609  trans-1,3-Dichloropropene
C06610  cis-1,3-Dichloropropene
C06611  trans-3-Chloro-2-propene-1-ol
C06612  cis-3-Chloro-2-propene-1-ol
C06613  trans-3-Chloroallyl aldehyde
C06614  trans-3-Chloroacrylic acid
C06615  cis-3-Chloroacrylic acid
C06752  1,2-Dichloroethane
C06753  2-Chloroethanol
C06754  Chloroacetaldehyde
C06755  Chloroacetic acid
C06789  Tetrachloroethene
C06790  Trichloroethene
C06791  trans-1,2-Dichloroethene
C06792  cis-1,2-Dichloroethene
C06793  Vinyl chloride
C07490  Trichloroethanol
C11148  TCE epoxide
C11149  Dichloroacetate
C11150  Trichloroacetate
C14866  Chloral
C16348  cis-3-Chloroallyl aldehyde
C18246  1,1,1-Trichloroethane
C18247  1,1-Dichloroethane
C18248  Chloroethane
C20303  Chloroethylene oxide
C21752  2-Hydroxyethyl-CoM
C21753  2-Chloro-2-hydroxyethyl-CoM
Reference
  Authors
Muller JA, Rosner BM, Von Abendroth G, Meshulam-Simon G, McCarty PL, Spormann AM.
  Title
Molecular identification of the catabolic vinyl chloride reductase from Dehalococcoides sp. strain VS and its environmental distribution.
  Journal
Appl Environ Microbiol 70:4880-8 (2004)
DOI:10.1128/AEM.70.8.4880-4888.2004
Reference
  Authors
Lee PK, Johnson DR, Holmes VF, He J, Alvarez-Cohen L.
  Title
Reductive dehalogenase gene expression as a biomarker for physiological activity of Dehalococcoides spp.
  Journal
Appl Environ Microbiol 72:6161-8 (2006)
DOI:10.1128/AEM.01070-06
Reference
  Authors
Torz M, Beschkov V
  Title
Biodegradation of monochloroacetic acid used as a sole carbon and energy source by Xanthobacter autotrophicus GJ10 strain in batch and continuous culture.
  Journal
Biodegradation 16:423-33 (2005)
DOI:10.1007/s10532-004-3614-8
Reference
  Authors
Hage JC, Hartmans S
  Title
Monooxygenase-mediated 1,2-dichloroethane degradation by Pseudomonas sp. strain DCA1.
  Journal
Appl Environ Microbiol 65:2466-70 (1999)
DOI:10.1128/AEM.65.6.2466-2470.1999
Reference
PMID:9687453
  Authors
Poelarends GJ, Wilkens M, Larkin MJ, van Elsas JD, Janssen DB.
  Title
Degradation of 1,3-dichloropropene by pseudomonas cichorii 170.
  Journal
Appl Environ Microbiol 64:2931-6 (1998)
DOI:10.1128/AEM.64.8.2931-2936.1998
Reference
  Authors
Sun B, Griffin BM, Ayala-del-Rio HL, Hashsham SA, Tiedje JM
  Title
Microbial dehalorespiration with 1,1,1-trichloroethane.
  Journal
Science 298:1023-5 (2002)
DOI:10.1126/science.1074675
Reference
  Authors
Hashimoto A, Iwasaki K, Nakasugi N, Nakajima M, Yagi O
  Title
Degradation pathways of trichloroethylene and 1,1,1-trichloroethane by Mycobacterium sp. TA27.
  Journal
Biosci Biotechnol Biochem 66:385-90 (2002)
DOI:10.1271/bbb.66.385
Reference
PMID:1768109
  Authors
Newman LM, Wackett LP
  Title
Fate of 2,2,2-trichloroacetaldehyde (chloral hydrate) produced during trichloroethylene oxidation by methanotrophs.
  Journal
Appl Environ Microbiol 57:2399-402 (1991)
DOI:10.1128/AEM.57.8.2399-2402.1991
Reference
PMID:8981984
  Authors
Newman LM, Wackett LP
  Title
Trichloroethylene oxidation by purified toluene 2-monooxygenase: products, kinetics, and turnover-dependent inactivation.
  Journal
J Bacteriol 179:90-6 (1997)
DOI:10.1128/JB.179.1.90-96.1997
Related
pathway
rn00620  Pyruvate metabolism
rn00630  Glyoxylate and dicarboxylate metabolism
rn00680  Methane metabolism
KO pathway
ko00625   

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