KEGG   Rattus norvegicus (rat): 288663
Entry
288663            CDS       T01003                                 

Gene name
Atxn2
Definition
(RefSeq) ataxin-2 isoform X1
  KO
K23625  ataxin 2/2L
Organism
rno  Rattus norvegicus (rat)
Pathway
rno05014  Amyotrophic lateral sclerosis
rno05017  Spinocerebellar ataxia
rno05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:rno00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    288663 (Atxn2)
   05017 Spinocerebellar ataxia
    288663 (Atxn2)
   05022 Pathways of neurodegeneration - multiple diseases
    288663 (Atxn2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:rno03019]
    288663 (Atxn2)
Messenger RNA biogenesis [BR:rno03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     288663 (Atxn2)
SSDB
Motif
Pfam: SM-ATX LsmAD PAM2 LSM
Other DBs
NCBI-GeneID: 288663
NCBI-ProteinID: XP_038946069
RGD: 1306637
Ensembl: ENSRNOG00000001256
Position
12
AA seq 1429 aa
MQVSAPKAPAGHPLCCIWWGGNQGPRRGLRTPGQPTVPVREAGPAAEDKHSLLEGQTRLS
EGGSPTALPRPRRANAAQRCARSSRVPDRPPSRLTFDFRLTLPTSGKESPPLCFASPRPP
GRVAPYASASPAPMRPSTDAAQRPAAGPEPRRLSGWAARRSLPRTARRGGRGGAVAYPSA
GPPPRGPGAPPRGPRSPPCASDCFGSNGNGASRPGSRRLFGVCGPPRPFVVVLLPLAPAT
APARACPLGVRASPPRSGVSSARPAPGCPRPACEPVYGPLTMSLKPQPQPPAPASGRKPG
GGLLSSPGAAPASAASTSSSVVPAPAAPVASSSAVAGGGRPGLGRGRNSSKGLPQPTISF
DGIYANVRMVHILTSVVGSKCEVQVKNGGVYEGVFKTYSPKCDLVLDAAHEKSTESSSGP
KREEIMESVLFKCSDFVVVQFKDTDSSYARRDAFTDSALSAKVNGEHKEKDLEPWDAGEL
TASEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREA
RANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNCSDREGHGTNTRENKYIPPGQR
NREVISWGSGRQSSPRMGQPGPGSMPSRATSHTSDFNPNAGSDQRVVNGVFILSFISFVL
SGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAP
VSTMPKRMSAEGPPRMSPKAQRHPRNHRVSAGRGSMSSGLEFVSHNPPSEAAAPPVARTS
PAGGTWSSVVSGVPRLSPKTHRPRSPRQNSAGNSPSGPVLASPQAGITPAEAVSMPVPAA
SPTPASPASNRALTPSIEAKDSRLQDQRQNSPAGNKENIKASETSPSFSKAENKGVSPVI
SEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLSKNREGEKSRDLMKDKTEASAKDSFIDS
GSSSCTSSSSKTNSPSASPSVLSNAEHKRGPEVTSQGVQTSSPACKQEKDDREERKDTTE
QVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPAPVYTQPVCFAPN
MMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAGKVPNMPQQRQEQHHQSTMMHPASAAGP
PIVATPPAAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPAHAQ
PGLVSSSAAQFGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHP
PHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPS
MTPASNTQSPQSSFPAAPQTVFTIHPSHVQPAYTTPPHMAHVPQAHVQSGMVPSHPTAHA
PMMLMTTQPPGGPQAALAQSALQPIPVSTTAHFPYMTHPSVQAHHQQQL
NT seq 4290 nt   +upstreamnt  +downstreamnt
atgcaggtctccgccccgaaggcgcccgcgggccatcctctatgttgcatctggtggggg
ggaaaccaaggtccccgaagggggctgaggacacccgggcagcccacggtgcccgtccgc
gaagcagggccagcggccgaagacaagcattccctcctcgaagggcagacccgcctcagc
gagggcggatcccccacggccctaccccgaccccggagagcgaacgcggcccagcgctgc
gcccgctcctcacgtgtccccgatcggcccccgagccgtctcacgttcgacttccgcctg
acccttccgacttccggtaaagagtcccccccgctctgtttcgcatctccgcgccctcca
ggccgcgtcgccccgtacgcgtccgcgagcccggctcccatgcgtccgtcgacagacgcc
gctcagcggcccgcggcaggccccgagccgcgccgcctgtcgggctgggccgcgcggcgc
tcgctcccgcggacggcgcggcgcggcgggcggggcggcgcggtagcatatccctccgcc
ggccctcccccgcgcggccccggcgcccctccccgcgggccgcgctcgccgccctgcgcc
tcagactgttttggtagcaacggcaacggcgcgtcccggcccggctcccggcggctgttc
ggtgtctgcgggcctccccgccccttcgtcgtcgtcctgctgcctctggcacccgcgacc
gcgccagcccgcgcctgcccgctcggcgtccgcgcgtccccgccgcgctccggcgtctcc
tcagcgcgcccggctcccggctgtccccgcccggcgtgcgagccggtgtatgggccgctc
accatgtcgctgaagccgcagccgcagccgcccgcgcccgccagtggccgcaagcccggc
ggcggcctgctctcgtcgcccggcgccgcgccggcctcggccgcgtcgacctcgtcttcc
gtggtgccggcccctgccgcgccggtggcgtcttcctcggcggtcgcgggcggcgggcgt
cccggcctgggcagaggtcggaacagtagcaaaggactgcctcagcctacgatttctttt
gacggaatctatgcaaacgtgaggatggttcatatacttacatcggttgtgggatcgaaa
tgtgaagtacaagtgaaaaacggaggtgtatatgaaggagtttttaaaacatacagtcct
aagtgtgatttggtacttgatgctgcacatgagaaaagtacagaatccagttcggggcca
aaacgtgaagaaataatggagagtgttttgttcaaatgctcagacttcgttgtggtacaa
tttaaagatacagactcgagttatgcacgaagagatgctttcactgactctgctctcagt
gctaaagtgaatggtgaacacaaggagaaggacctggagccctgggatgcaggggagctc
acagccagcgaggagctggaggctctggagaatgatgtgtctaacggatgggatcccaat
gatatgtttcgatataatgaagagaattacggtgtggtgtccacatacgatagtagttta
tcttcatatacggttcccttagaaagggacaactcagaagaatttctaaaacgggaggca
agggcaaaccagttagcagaagaaatcgagtccagtgctcagtacaaagctcgtgtggcc
cttgagaatgatgaccggagtgaggaagagaagtacacagcagtccagagaaactgcagt
gaccgggaaggtcatggcaccaacactagggaaaataaatatattcctcctggacaaaga
aacagagaagtcatatcctggggaagtgggagacagagctcaccacggatgggccagcct
ggaccaggctccatgccatcaagagctacttctcacacttcagatttcaacccgaatgct
ggctcagaccaaagagtagttaatggagtttttatactttccttcatatcatttgttctg
tcaggtgttccctggccatcgccttgcccatctccttcctctcgcccaccttctcgctac
cagtcaggtcccaactctcttccacctcgggcagccacccctacacggccgccctccagg
cccccctcgaggccctccagacccccgtctcacccctctgctcatggttctccagctcct
gtctctactatgcctaaacgcatgtctgcagaaggcccaccaaggatgtctccaaaggca
cagcggcaccctcggaatcatagagtctccgctgggagaggctccatgtctagtggccta
gaatttgtatcccacaatcccccaagtgaagcagctgctcctccagtggcaaggaccagt
cctgcagggggaacgtggtcctcagtggtcagtggggttccaagactatctcccaaaact
cacagacccaggtctcccaggcagaacagcgctggaaactctcccagcgggcctgtgctc
gcttctccccaagctggcatcacccctgccgaagccgtttccatgccggtccccgccgcg
tcccctactcctgccagccctgcgtccaacagagctctgaccccatctatcgaggcgaaa
gattccaggcttcaagatcagaggcagaactctcctgcagggaataaagaaaatattaaa
gcaagtgaaacatcacctagcttttcaaaagctgaaaacaaaggtgtgtcaccagttatc
tctgaacacagaaaacagatcgatgatttaaagaagtttaagaatgattttaggttacag
ccaagttctacgtctgaatctatggatcaactactaagcaaaaacagagaaggagaaaag
tcacgagatttgatgaaagacaaaacggaagcaagtgctaaggacagcttcattgacagt
ggcagcagcagctgcaccagcagcagcagcaagaccaacagccccagcgcctccccttct
gtgcttagtaatgcagagcacaagagggggcctgaggtcacgtcccagggggtgcagact
tccagtccggcctgcaaacaagagaaggatgaccgagaagagcggaaagacacaaccgag
caagttaggaagtcgactttgaatcccaatgcaaaggagttcaaccctcgttctttctct
cagccaaagccttctactaccccaacgtcgcctcggcctcaagcccagcccagcccgtcc
atggtgggtcatcagcagccagctccagtgtacacgcagcctgtgtgctttgcacccaat
atgatgtaccctgtcccagtgagcccaggcgtgcagcctttatacccaatacctatgacg
cccatgccagtgaaccaagccaagacatatagagcaggtaaagtaccaaatatgccccaa
cagcgacaagagcagcaccatcaaagcaccatgatgcaccctgcctccgcagcagggccg
cctatcgttgccaccccgcccgccgcttactccacgcagtacgttgcctacagccctcag
cagtttcccaaccagcctttggtccagcacgtgccgcattatcagtctcagcatcctcat
gtgtacagtcctgtcatacaaggtaatgccaggatgatggcaccaccagcacatgctcag
cctggtttagtgtcgtcttcagctgctcagttcggggctcacgagcagacgcatgccatg
tatgcatgtcccaaattaccatacaacaaggagacaagcccttctttctactttgccatt
tccaccggctccctcgctcagcagtacgcacatcctaatgccaccctgcatccacaccct
ccacatcctcagccttcggccactcccaccggacagcaacaaagccagcatggtggaagt
catcctgcacccagtcctgttcagcaccatcagcaccaggccgcccaggctcttcacctg
gccagtccacagcagcagtcggccatttatcacgcggggctggcaccaacaccaccttcc
atgacacctgcctctaatacacagtctccacagagcagtttcccagcagcaccacagaca
gtcttcaccatccatccttctcatgttcagccggcatacaccaccccaccccacatggcc
cacgtacctcaggctcatgtacagtcaggaatggttccttctcatccaactgcccatgcg
ccaatgatgcttatgacgacacagccacccggcggtccccaggccgccctcgctcaaagt
gcactacagcccattccagtctcgacaacagcgcatttcccctatatgacgcacccttca
gtacaagcccaccaccaacagcagttgtaa

KEGG   Rattus norvegicus (rat): 361649
Entry
361649            CDS       T01003                                 

Gene name
Atxn2l
Definition
(RefSeq) ataxin-2-like protein
  KO
K23625  ataxin 2/2L
Organism
rno  Rattus norvegicus (rat)
Pathway
rno05014  Amyotrophic lateral sclerosis
rno05017  Spinocerebellar ataxia
rno05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:rno00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    361649 (Atxn2l)
   05017 Spinocerebellar ataxia
    361649 (Atxn2l)
   05022 Pathways of neurodegeneration - multiple diseases
    361649 (Atxn2l)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:rno03019]
    361649 (Atxn2l)
Messenger RNA biogenesis [BR:rno03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     361649 (Atxn2l)
SSDB
Motif
Pfam: SM-ATX LsmAD PAM2 LSM14
Other DBs
NCBI-GeneID: 361649
NCBI-ProteinID: NP_001123569
RGD: 1565868
Ensembl: ENSRNOG00000018686
UniProt: B3DMA1
Position
1
AA seq 1072 aa
MLKPQPPQQTSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLPATAAPPGPPTVVSPCLG
PAAAAGSGLRRGAESILAAPAPQQHQERPGAVAIGSVRGQTTGKGPPQSPVFEGVYNNSR
MLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIVDT
MVFKPSDVLLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYD
LESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLARE
IESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLVSREGKYIPLPQRVREGPRG
GVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGGKTL
SSPNNRPSGEASVPPTSAVGRMYPPRSPKSAAPAPVSASCPEPPIGSAVASSASIPVTSS
VVDPGAGSISPASPKLSLAPTDVKELPTKEPSRSLEAQELARIAGKVPGLQNEQKRFQLE
ELRKFGAQFKLQPSSSSETGLDPFPSRILKEEAKGKEKEVDGLLTSDPMGSPVSSKAESI
LDKEDKVPLAAVAGSEGPEQLQPPCPSQTGSPPVGLIKGDDKEEGPVTEQVKKSTLNPNA
KEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAV
QAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAAGPPLVAAT
PYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQY
PSAEQPTPQALYATVHQSYPHHATQLHGHQPQPATTPTGSQPQSQHAAPSPVQAGQAPHL
GSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHPHQQLPHGFTNMAHV
TQAHVQTGVTAAPPPHPGAPHPPQVMLLHPPQGHGGPPQGAVPPSGVPALSASTPSPYPY
IGHPQGEQPGQAPGFPGGADDRIREFSLAGGIWHGRAEGLQVGQDARVLGGD
NT seq 3219 nt   +upstreamnt  +downstreamnt
atgttgaagcctcagccgccacaacagacctcccagccccagcagccgccccccacgcaa
caggccgtggctcgccggcctcccggcgggactagccctcccaacggcggcctcccggga
ccgctgcccgctaccgcggctcccccggggcctcccacagtggtctctccgtgcctgggg
cctgcagccgctgccggcagcgggctccgccgcggagccgaaagcatcttggcggcgcca
gcgccgcagcagcatcaagaacggccaggggcagtggctatcggcagcgtcaggggacag
accaccggaaagggacccccacagtcaccagtgtttgaaggtgtctataacaattccagg
atgctgcatttcctgacagctgtagtgggttctacctgtgatgtaaaagtgaaaaatggc
accacttatgagggcattttcaagacgctgagctcaaagtttgaactggcagtagatgcg
gtacatcggaaagcctctgagccagcaggtgggcctcgtcgggaagacattgtggacacc
atggtgtttaaaccaagtgatgttctgcttgtccacttccgaaatgttgacttcaattat
gctactaaagacaagttcactgactcagccattgccatgaactctaaggtgaatggagaa
cacaaagagaaggtgcttcagcgttgggagggcggtgacagcaacagtgatgactacgat
ctggaatccgatatgtctaatggatgggatcctaatgagatgttcaaatttaatgaggag
aactatggagtgaagaccacctatgacagcagtctatcttcttacacggttcccttagaa
aaggacaactctgaagagtttcggcagcgggagcttcgcgcggcccagttggctcgggag
attgagtctagtccccagtaccgtctacggattgccatggaaaatgacgacgggcgaacc
gaggaggagaagcacagtgcagttcagcggcaggggtccgggcgggagagccccagcttg
gtgtccagggaagggaaatatatccctctgcctcaacgagttcgggaaggtccccgggga
ggagttcgatgcagcagttctcgaggagggcggcctggccttagctctttgccacctcgt
ggccctcaccatcttgacaacagcagtcctggtcctgggtctgaggcacgtggtatcaat
ggaggtccttcccgcatgtcccccaaggcacagcggcctctgagaggtggcaagacctta
tcttcacccaacaataggccttctggagaagcttctgttcctccaacatctgcagtgggc
cggatgtaccctccacggtctcccaagtctgctgcccctgccccagtctcagcttcctgt
cctgagcctcccattggttcagcagtagcatcctctgcctccatccctgtgacatcatca
gttgtggatcctggagcaggctctatttccccagcatctccaaaactctccctggcccct
acagatgtaaaagaactcccaaccaaggagcccagtaggagtttggaagcccaagagctg
gcccgcatagctgggaaagtccctggccttcagaatgaacaaaaacgctttcagttggaa
gaactgaggaaatttggggcccagtttaagcttcaacctagtagctcctctgagacgggc
ctggatccatttccttcccggatcttgaaagaagaggccaaaggaaaggagaaagaagtg
gatggtctattgacttcagatcctatgggatccccagtctcctccaaggcagaatccata
ttggataaggaagacaaagtgcccctggcagcagtagcggggtctgaggggccagaacag
ctccaaccaccttgccccagccaaactggcagtcctccagtgggcctcatcaagggagat
gacaaagaggagggcccggttactgaacaagtaaagaagtctactttgaaccccaatgcc
aaggagttcaatccaacaaagcctctgctgtctgtgaacaaatctaccagtactccaact
tcaccagggccccgtactcattcaacaccttccataccggtgctgacagcaggccagagt
gggctctacagtccccagtacatctcatatatacctcagatccacatgggaccagctgtg
caggcacctcagatgtatccatatcctgtatccaattcggtgcctgggcagcagggcaag
taccggggtgcaaaaggctcacttcccccccagcgctctgaccaacaccaaccagcctca
gcccctccaatgatgcaggctgctgctgctgctgctggcccacccttggtggctgccaca
ccttattcctcctacatcccttacaacccacagcagttcccaggccagcctgccatgatg
cagcccatggcacactacccttcacagccggtgttcgcccctatgcttcaaagtaatcca
cgaatgttgacatcgggaagccatccccaggccatcgtgtcatcctccactcctcagtac
ccttctgcagagcagcctaccccccaagccctttatgccactgttcaccagtcctatcca
caccatgccacgcagctccatggccaccagcctcagccggccaccactcctactgggagc
caaccacaatcccagcatgcggcccccagtcccgttcaggcggggcaggccccacacctg
ggcagtggacaaccacagcagaatctgtaccatccaggggccctaacaggcacgccacct
tctctaccaccgggaccttctgcccagtcccctcaaagcagcttcccccagccagctgct
gtgtatgccatccatccccaccagcagctgccccacggcttcaccaacatggcccatgtt
acccaggcccatgtccaaactggagtcacagcagccccgcccccacaccctggggctccc
cacccgccccaggtgatgctgctgcaccccccccagggccatgggggccccccccaaggc
gcggtgcccccgagtggggtgcctgcactctcagcttccacaccctcaccctacccctac
atcggacacccccaaggtgagcagcctggccaggcgcctggatttccaggaggagccgat
gacaggattcgtgagttctcgttagctgggggaatttggcatggaagagctgaggggctg
caggtggggcaggatgcacgggttctgggtggggattga

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