KEGG   Rattus norvegicus (rat): 29499
Entry
29499             CDS       T01003                                 

Gene name
Shh
Definition
(RefSeq) sonic hedgehog protein precursor
  KO
K11988  sonic hedgehog
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04340  Hedgehog signaling pathway
rno04360  Axon guidance
rno05200  Pathways in cancer
rno05205  Proteoglycans in cancer
rno05217  Basal cell carcinoma
rno05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    29499 (Shh)
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    29499 (Shh)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    29499 (Shh)
   05205 Proteoglycans in cancer
    29499 (Shh)
  09162 Cancer: specific types
   05226 Gastric cancer
    29499 (Shh)
   05217 Basal cell carcinoma
    29499 (Shh)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:rno01002]
    29499 (Shh)
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:rno00536]
    29499 (Shh)
Peptidases and inhibitors [BR:rno01002]
 Cysteine peptidases
  Family C46: hedgehog family
   29499 (Shh)
Glycosaminoglycan binding proteins [BR:rno00536]
 Heparan sulfate / Heparin
  Morphogens
   29499 (Shh)
SSDB
Motif
Pfam: HH_signal Hint Peptidase_M15_3
Other DBs
NCBI-GeneID: 29499
NCBI-ProteinID: NP_058917
RGD: 3673
Ensembl: ENSRNOG00000006120
UniProt: Q63673
Position
4
AA seq 437 aa
MLLLLARCFLVALASSLLVCPGLACGPGRGFGKRQHPKKLTPLAYKQFIPNVAEKTLGAS
GRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPG
VKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKA
RIHCSVKAENSVAAKSDGCFPGSATVHLEQGGTKLVKDLSPGDRVLAADDQGRLLYSDFL
TFLDRDEGAKKVFYVIETREPRERLLLTAAHLLFVAPHNDSGPTPGPSPLFASRVRPGQR
VYVVAERGGDRRLLPAAVHSVTLREEAAGAYAPLTADGTILINRVLASCYAVIEEHSWAH
RAFAPFRLAHALLAALAPARTDGGGGGSIPAPQSVAEARGAGPPAGIHWYSQLLYHIGTW
LLDSETLHPLGMAVKSS
NT seq 1314 nt   +upstreamnt  +downstreamnt
atgctgctgctgctggccagatgttttctggtggcccttgcttcctcgctgctggtgtgc
cccggactggcctgtgggcccggcagggggtttggaaagaggcagcaccccaaaaagctg
acccctttagcctacaagcagtttatccccaacgtagccgagaagaccctaggggccagc
ggccgatatgaagggaagatcacaagaaactccgaacgatttaaggaactcacccccaat
tacaaccccgacatcatatttaaggatgaggaaaacactggagcagaccggctgatgact
cagaggtgcaaagacaagttaaatgccttggccatctccgtgatgaaccagtggcctgga
gtgaagcttcgagtgactgagggctgggatgaggacggccatcattcagaggagtctcta
cactatgagggtcgagcagtggacatcaccacgtctgacagggaccgcagcaagtatggc
atgctggctcgcctggctgtggaggctggattcgactgggtctactatgaatccaaagct
cgcatccactgctctgtgaaagcagagaactccgtggcggccaaatctgacggctgcttc
ccgggatcagccacagtgcacctggagcagggtggcaccaagttagtgaaggatctaagt
cccggggaccgcgtgctggcggctgacgaccagggccggctgctgtacagcgacttcctc
accttcctggaccgcgacgaaggtgccaagaaggtcttctacgtgatcgagacgcgggag
ccgcgggagcgtctgctgctcactgccgcgcacctgctcttcgtggcgccgcacaacgac
tccgggcccactccgggaccgagcccactcttcgccagccgcgtgcgtccggggcagcgc
gtgtacgtggtggctgaacgcggcggggaccgccggctgctgcccgccgcggtgcacagc
gtaacgctacgagaggaggcggcgggtgcgtacgcgccgctcacggcggacggcaccatt
ctcatcaaccgggtgctcgcctcgtgctacgcagtcatcgaggagcacagctgggcacac
cgggccttcgcgcccttccgcctggcgcacgcgctgctggccgcgctggcacccgcccgc
acggacggcgggggcgggggcagcatccctgccccgcaatctgtagcggaagcgaggggc
gcagggccgcctgcgggcatccactggtactcgcagctgctgtaccacattggcacctgg
ctgttggacagcgagaccctgcatcccttgggaatggcagtcaagtccagctga

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