GenomeNet

Database: RefSeq
Entry: NC_002695
LinkDB: NC_002695
Original site: NC_002695 
LOCUS       NC_002695            5498578 bp    DNA     circular CON 12-FEB-2021
DEFINITION  Escherichia coli O157:H7 str. Sakai DNA, complete genome.
ACCESSION   NC_002695
VERSION     NC_002695.2
DBLINK      BioProject: PRJNA226
            BioSample: SAMN01911278
KEYWORDS    RefSeq.
SOURCE      Escherichia coli O157:H7 str. Sakai
  ORGANISM  Escherichia coli O157:H7 str. Sakai
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Hayashi,T., Makino,K., Ohnishi,M., Kurokawa,K., Ishii,K.,
            Yokoyama,K., Han,C.G., Ohtsubo,E., Nakayama,K., Murata,T.,
            Tanaka,M., Tobe,T., Iida,T., Takami,H., Honda,T., Sasakawa,C.,
            Ogasawara,N., Yasunaga,T., Kuhara,S., Shiba,T., Hattori,M. and
            Shinagawa,H.
  TITLE     Complete genome sequence of enterohemorrhagic Escherichia coli
            O157:H7 and genomic comparison with a laboratory strain K-12
  JOURNAL   DNA Res. 8 (1), 11-22 (2001)
   PUBMED   11258796
  REMARK    Erratum:[DNA Res 2001 Apr 27;8(2):96]
REFERENCE   2
  AUTHORS   Yokoyama,K., Makino,K., Kubota,Y., Watanabe,M., Kimura,S.,
            Yutsudo,C.H., Kurokawa,K., Ishii,K., Hattori,M., Tatsuno,I.,
            Abe,H., Yoh,M., Iida,T., Ohnishi,M., Hayashi,T., Yasunaga,T.,
            Honda,T., Sasakawa,C. and Shinagawa,H.
  TITLE     Complete nucleotide sequence of the prophage VT1-Sakai carrying the
            Shiga toxin 1 genes of the enterohemorrhagic Escherichia coli
            O157:H7 strain derived from the Sakai outbreak
  JOURNAL   Gene 258 (1-2), 127-139 (2000)
   PUBMED   11111050
REFERENCE   3
  AUTHORS   Ohnishi,M., Murata,T., Nakayama,K., Kuhara,S., Hattori,M.,
            Kurokawa,K., Yasunaga,T., Yokoyama,K., Makino,K., Shinagawa,H. and
            Hayashi,T.
  TITLE     Comparative analysis of the whole set of rRNA operons between an
            enterohemorrhagic Escherichia coli O157:H7 Sakai strain and an
            Escherichia coli K-12 strain MG1655
  JOURNAL   Syst. Appl. Microbiol. 23 (3), 315-324 (2000)
   PUBMED   11108008
REFERENCE   4
  AUTHORS   Makino,K., Yokoyama,K., Kubota,Y., Yutsudo,C.H., Kimura,S.,
            Kurokawa,K., Ishii,K., Hattori,M., Tatsuno,I., Abe,H., Iida,T.,
            Yamamoto,K., Onishi,M., Hayashi,T., Yasunaga,T., Honda,T.,
            Sasakawa,C. and Shinagawa,H.
  TITLE     Complete nucleotide sequence of the prophage VT2-Sakai carrying the
            verotoxin 2 genes of the enterohemorrhagic Escherichia coli O157:H7
            derived from the Sakai outbreak
  JOURNAL   Genes Genet. Syst. 74 (5), 227-239 (1999)
   PUBMED   10734605
REFERENCE   5  (bases 1 to 5498578)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-AUG-2018) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   6  (bases 1 to 5498578)
  AUTHORS   Ogura,Y., Kurokawa,K., Hayashi,T. and Hattori,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUN-2000) Contact:Yoshitoshi Ogura Kyushu University;
            31-1 Maidashi Higashi-ku, Fukuoka, Fukuoka 812-8582, Japan
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to BA000007.
            On Aug 15, 2018 this sequence version replaced NC_002695.1.
            On May 10, 2018 this sequence version replased gi: 47118301
            
            This update is obtained as follows: the Sakai genome was
            resequenced by illumina MiSeq and PacBio RS II sequencers and 78
            sites of single base error, 11 sites of insertion (10 one-base
            insertions and a 141-base insertion) and 16 sites of deletion (14
            one-base deletions, a three-base deletion and a six-base deletion)
            were corrected. Annotation was performed using DFAST
            auto-annotation system with manual curation.
            
            This work was done in collaboration with Tetsuya Hayashi, Makoto
            Ohnishi, Keisuke Nakayama (Miyazaki Medical College), Kozo Makino,
            Ken Kurokawa, Katsushi Yokoyama, Masashi Tanaka, Takeshi Honda,
            Teruo Yasunaga, Hideo Shinagawa (Osaka University), Takahiro Murata
            (Shinshu University), Chang-Gyun Han, Eiichi Ohtsubo, Toru Tobe,
            Chihiro Sasakawa (University of Tokyo), Hideto Takami (Japan Marine
            Science and Technology Center), Naotake Ogasawara (Nara Institute
            of Science and Technology), Satoru Kuhara (Kuyshu University), and
            supported by the Research for the Future Program of the Japan
            Society for the Promotion of Science.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..5498578
                     /organism="Escherichia coli O157:H7 str. Sakai"
                     /mol_type="genomic DNA"
                     /strain="Sakai"
                     /sub_strain="RIMD 0509952"
                     /serovar="O157:H7"
                     /db_xref="taxon:386585"
     gene            190..273
                     /gene="thrL"
                     /locus_tag="ECs_0001"
                     /db_xref="GeneID:913387"
     CDS             190..273
                     /gene="thrL"
                     /locus_tag="ECs_0001"
                     /codon_start=1
                     /transl_table=11
                     /product="thr operon leader peptide"
                     /protein_id="NP_308028.1"
                     /db_xref="GeneID:913387"
                     /translation="MKRISTTITTTITTTITITITTGNGAG"
     gene            354..2816
                     /gene="thrA"
                     /locus_tag="ECs_0002"
                     /db_xref="GeneID:913388"
     CDS             354..2816
                     /gene="thrA"
                     /locus_tag="ECs_0002"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartokinase I"
                     /protein_id="NP_308029.1"
                     /db_xref="GeneID:913388"
                     /translation="MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKIT
                     NHLVAMIEKTISGQDALPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIK
                     HVLHGISLLGQCPDSINAALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHY
                     LESTVDIAESTRRIAASRIPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACL
                     RADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQF
                     QIPCLIKNTGNPQAPGTLIGASRDEDELPVKGISNLNNMAMFSVSGPGMKGMVGMAAR
                     VFAAMSRARISVVLITQSSSEYSISFCVPQSDCVRAERAMQEEFYLELKEGLLEPLAV
                     TERLAIISVVGDGMRTLRGISAKFFAALARANINIVAIAQGSSERSISVVVNNDDATT
                     GVRVTHQMLFNTDQVIEVFVIGVGGVGGALLEQLKRQQSWLKNKHIDLRVCGVANSKA
                     LLTNVHGLNLENWQEELAQAKEPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYAD
                     FLREGFHVVTPNKKANTSSMDYYHLLRHAAEKSRRKFLYDTNVGAGLPVIENLQNLLN
                     AGDELMKFSGILSGSLSYIFGKLDEGMSFSEATTLAREMGYTEPDPRDDLSGMDVARK
                     LLILARETGRELELADIEIEPVLPAEFNAEGDVAAFMANLSQLDDLFAARVAKARDEG
                     KVLRYVGNIDEDGVCRVKIAEVDGNDPLFKVKNGENALAFYSHYYQPLPLVLRGYGAG
                     NDVTAAGVFADLLRTLSWKLGV"
     misc_feature    354..2813
                     /gene="thrA"
                     /locus_tag="ECs_0002"
                     /note="bifunctional aspartokinase I/homoserine
                     dehydrogenase I; Provisional; Region: thrA; PRK09436"
                     /db_xref="CDD:181856"
     gene            2818..3750
                     /gene="thrB"
                     /locus_tag="ECs_0003"
                     /db_xref="GeneID:913390"
     CDS             2818..3750
                     /gene="thrB"
                     /locus_tag="ECs_0003"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="NP_308030.1"
                     /db_xref="GeneID:913390"
                     /translation="MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVESAETF
                     SLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACS
                     VVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDI
                     ISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQ
                     PELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTA
                     QRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN"
     gene            3751..5037
                     /gene="thrC"
                     /locus_tag="ECs_0004"
                     /db_xref="GeneID:913393"
     CDS             3751..5037
                     /gene="thrC"
                     /locus_tag="ECs_0004"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine synthase"
                     /protein_id="NP_308031.1"
                     /db_xref="GeneID:913393"
                     /translation="MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEID
                     EMLKLDFVTRSAKILSAFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGP
                     TLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRG
                     KISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISR
                     LLAQICYYFEAVAQLPQEARNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVN
                     DTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDE
                     TTQQTMRELKELGYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVEAILGE
                     TLDLPKELAERADLPLLSHNLPADFAALRKLMMNHQ"
     misc_feature    3754..5019
                     /gene="thrC"
                     /locus_tag="ECs_0004"
                     /note="Threonine synthase catalyzes the final step of
                     threonine biosynthesis. The conversion of
                     O-phosphohomoserine into threonine and inorganic phosphate
                     is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD
                     includes members from higher plants, cyanobacteria;
                     Region: Thr-synth_2; cd01560"
                     /db_xref="CDD:107203"
     misc_feature    order(4069..4071,4492..4497,4876..4878)
                     /gene="thrC"
                     /locus_tag="ECs_0004"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:107203"
     misc_feature    4069..4071
                     /gene="thrC"
                     /locus_tag="ECs_0004"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:107203"
     gene            5251..5547
                     /gene="yaaX"
                     /locus_tag="ECs_0005"
                     /db_xref="GeneID:913394"
     CDS             5251..5547
                     /gene="yaaX"
                     /locus_tag="ECs_0005"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308032.1"
                     /db_xref="GeneID:913394"
                     /translation="MKKMQSIVLALSLVLVAPMATQAAEITLVPSVKLQIGDRDNRGY
                     YWDGGHWRDHGWWKQHYEWRGNRWHPHGPPPPPRHHKKAHHDHHGGHGPGKHHR"
     misc_feature    5323..>5454
                     /gene="yaaX"
                     /locus_tag="ECs_0005"
                     /note="Protein of unknown function (DUF2502); Region:
                     DUF2502; pfam10697"
                     /db_xref="CDD:431443"
     gene            complement(5700..6476)
                     /gene="yaaA"
                     /locus_tag="ECs_0006"
                     /db_xref="GeneID:913395"
     CDS             complement(5700..6476)
                     /gene="yaaA"
                     /locus_tag="ECs_0006"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide resistance protein"
                     /protein_id="NP_308033.1"
                     /db_xref="GeneID:913395"
                     /translation="MLILISPAKTLDYQSPLTTTRYTLPELLDNSQQLIHEARKLTPP
                     QISTLMRISDKLAGINAARFHDWQPDFTPENARQAILAFKGDVYTGLQAETFSEDDFD
                     FAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENARGKDLYQFWGDIITNKLNEALA
                     AQGDNVVINLASDEYFKSVKPKKLNAEIIKPVFLDEKNGKFKIISFYAKKARGLMSRF
                     IIENRLTKPEQLTGFNSEGYFFDEASSSNGELVFKRYEQR"
     misc_feature    complement(5706..6476)
                     /gene="yaaA"
                     /locus_tag="ECs_0006"
                     /note="peroxide stress protein YaaA; Region: PRK02101"
                     /db_xref="CDD:234999"
     gene            complement(6546..7976)
                     /gene="yaaJ"
                     /locus_tag="ECs_0007"
                     /db_xref="GeneID:913398"
     CDS             complement(6546..7976)
                     /gene="yaaJ"
                     /locus_tag="ECs_0007"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid carrier protein"
                     /protein_id="NP_308034.1"
                     /db_xref="GeneID:913398"
                     /translation="MPDFFSFINSVLWGSVMIYLLFGAGCWFTFRTGFVQFRYIRQFG
                     KSLKNSIHPQPGGLTSFQSLCTSLAARVGSGNLAGVALAITAGGPGAVFWMWVAAFIG
                     MATSFAECSLAQLYKERDVNGQFRGGPAWYMARGLGMRWMGVLFAVFLLIAYGIIFSG
                     VQANAVARALSFSFDFPPLVTGIILAVFALLAIIRGLHGVARLMQGFVPLMAIIWVLT
                     SLVICVINIGQLPHVIWSIFESAFGWQEAAGGAAGYTLSQAITNGFQRSMFSNEAGMG
                     STPNAAAAAASWPPHPAAQGIVQMIGIFIDTLVICTASAMLILLAGNGTTYMPLEGIQ
                     LIQKAMRVLMGSWGAEFVTLVVILFAFSSIVANYIYAENNLFFLRLNNPKAIWCLRIC
                     TFATVIGGTLLSLPLMWQLADIIMACMAITNLTAILLLSPVVHTIASDYLRQRKLGVR
                     PVFDPLRYPDIGRQLSRDAWDDVSQE"
     gene            8255..9208
                     /gene="talB"
                     /locus_tag="ECs_0008"
                     /db_xref="GeneID:913400"
     CDS             8255..9208
                     /gene="talB"
                     /locus_tag="ECs_0008"
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase B"
                     /protein_id="NP_308035.1"
                     /db_xref="GeneID:913400"
                     /translation="MTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQ
                     IPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTEVDARLS
                     YDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFS
                     FAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGY
                     ETVVMGASFRNIGEILELAGCDRLTIAPALLKELAESEGAIERKLSYTGEVKARPARI
                     TESEFLWQHNQDPMAVDKLAEGIRKFAIDQEKLEKMIGDLL"
     misc_feature    8255..9205
                     /gene="talB"
                     /locus_tag="ECs_0008"
                     /note="transaldolase B; Provisional; Region: PRK05269"
                     /db_xref="CDD:235381"
     misc_feature    order(8303..8305,8351..8353,8357..8362,8534..8536,
                     8540..8542,8648..8650,8714..8716,8720..8722,8780..8782,
                     8795..8797)
                     /gene="talB"
                     /locus_tag="ECs_0008"
                     /note="active site"
                     /db_xref="CDD:188644"
     misc_feature    order(8564..8566,9089..9091,9098..9100,9110..9115,
                     9131..9133,9140..9142,9152..9154)
                     /gene="talB"
                     /locus_tag="ECs_0008"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:188644"
     misc_feature    8648..8650
                     /gene="talB"
                     /locus_tag="ECs_0008"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:188644"
     gene            9323..9910
                     /gene="mog"
                     /locus_tag="ECs_0009"
                     /db_xref="GeneID:913401"
     CDS             9323..9910
                     /gene="mog"
                     /locus_tag="ECs_0009"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdochelatase incorporating molybdenum into
                     molybdopterin"
                     /protein_id="NP_308036.1"
                     /db_xref="GeneID:913401"
                     /translation="MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELET
                     RLIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQ
                     MRQISLHFVPTAILSRQVGVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFA
                     SVPYCIQLLEGPYVETAPEVVAAFRPKSARRDVSE"
     misc_feature    9323..9901
                     /gene="mog"
                     /locus_tag="ECs_0009"
                     /note="molybdenum cofactor biosynthesis protein MogA;
                     Provisional; Region: mogA; PRK09417"
                     /db_xref="CDD:181837"
     misc_feature    order(9545..9553,9641..9643,9719..9724,9734..9736,
                     9743..9745)
                     /gene="mog"
                     /locus_tag="ECs_0009"
                     /note="MPT binding site [active]"
                     /db_xref="CDD:238451"
     misc_feature    order(9551..9553,9557..9562,9566..9568,9578..9580,
                     9602..9610,9623..9625,9632..9637,9665..9667,9674..9676,
                     9827..9829)
                     /gene="mog"
                     /locus_tag="ECs_0009"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238451"
     gene            complement(9945..10511)
                     /gene="satP"
                     /locus_tag="ECs_0010"
                     /db_xref="GeneID:913402"
     CDS             complement(9945..10511)
                     /gene="satP"
                     /locus_tag="ECs_0010"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate-acetate transporter"
                     /protein_id="NP_308037.1"
                     /db_xref="GeneID:913402"
                     /translation="MGNTKLANPAPLGLMGFGMTTILLNLHNVGYFALDGIILAMGIF
                     YGGIAQIFAGLLEYKKGNTFGLTAFTSYGSFWLTLVAILLMPKLGLTDAPNAQFLGVY
                     LGLWGVFTLFMFFGTLKGARVLQFVFFSLTVLFALLAIGNIAGNAAIIHFAGWIGLIC
                     GASAIYLAMGEVLNEQFGRTVLPIGESH"
     misc_feature    complement(9948..10511)
                     /gene="satP"
                     /locus_tag="ECs_0010"
                     /note="acetate uptake transporter; Region: PRK10659"
                     /db_xref="CDD:182625"
     gene            complement(10660..11373)
                     /gene="yaaW"
                     /locus_tag="ECs_0012"
                     /db_xref="GeneID:913403"
     CDS             complement(10660..11373)
                     /gene="yaaW"
                     /locus_tag="ECs_0012"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308038.1"
                     /db_xref="GeneID:913403"
                     /translation="MNVNYLNDSDLDFLQHCSEEQLANFARLLTHNEKGKTRLSSVLM
                     RNELFKSMEGHPEQHRRNWQLIAGELQHFGGDSIANKLRGHGKLYRAILLDVSKRLKL
                     KADKEMSTFEIEQQLLEQFLRNTWKKMDEEHKQEFLHAVDARVNELEELLPLLMKDKL
                     LAKGVSHLLSSQLTRILRTHAAMSVLGHGLLRGAGLGGPVGAALNGVKAVSGSSYRVT
                     IPAVLQIACLRRMVSATQV"
     misc_feature    complement(10663..11373)
                     /gene="yaaW"
                     /locus_tag="ECs_0012"
                     /note="acidic protein MsyB; Region: PRK10236"
                     /db_xref="CDD:182323"
     gene            complement(11399..11803)
                     /gene="yaaI"
                     /locus_tag="ECs_0013"
                     /db_xref="GeneID:913405"
     CDS             complement(11399..11803)
                     /gene="yaaI"
                     /locus_tag="ECs_0013"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308040.1"
                     /db_xref="GeneID:913405"
                     /translation="MKSVFTISASLAISLMLCCTAQANDHKLLGVIAMPRNETNALAL
                     KLPVCRIVKRIQLSADHGDLQLSGASVYFKAARSASQSLNIPSEIKEGQTTDWININS
                     DNDNKRCVSKITFSGHTVNSSDMATLKIIGDD"
     misc_feature    complement(11402..11803)
                     /gene="yaaI"
                     /locus_tag="ECs_0013"
                     /note="DUF2541 family protein; Region: PRK10154"
                     /db_xref="CDD:182272"
     gene            12180..14096
                     /gene="dnaK"
                     /locus_tag="ECs_0014"
                     /db_xref="GeneID:913406"
     CDS             12180..14096
                     /gene="dnaK"
                     /locus_tag="ECs_0014"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone Hsp70"
                     /protein_id="NP_308041.1"
                     /db_xref="GeneID:913406"
                     /translation="MGKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQ
                     DGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAW
                     VEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRI
                     AGLEVKRIINEPTAAALAYGLDKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEV
                     LATNGDTHLGGEDFDSRLINYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA
                     QQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDI
                     DDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLL
                     DVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAAD
                     NKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLN
                     EDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIE
                     SALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQTAGADASANNAKDD
                     DVVDAEFEEVKDKK"
     misc_feature    12180..14093
                     /gene="dnaK"
                     /locus_tag="ECs_0014"
                     /note="molecular chaperone DnaK; Provisional; Region:
                     dnaK; PRK00290"
                     /db_xref="CDD:234715"
     gene            14185..15315
                     /gene="dnaJ"
                     /locus_tag="ECs_0015"
                     /db_xref="GeneID:913407"
     CDS             14185..15315
                     /gene="dnaJ"
                     /locus_tag="ECs_0015"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone Hsp40"
                     /protein_id="NP_308042.1"
                     /db_xref="GeneID:913407"
                     /translation="MAKQDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAE
                     AKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIF
                     GGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQT
                     CPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPA
                     GVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAAL
                     GGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLN
                     EKQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR"
     misc_feature    14185..15300
                     /gene="dnaJ"
                     /locus_tag="ECs_0015"
                     /note="chaperone protein DnaJ; Provisional; Region:
                     PRK10767"
                     /db_xref="CDD:236757"
     gene            complement(15419..15628)
                     /gene="mokC"
                     /locus_tag="ECs_0016"
                     /db_xref="GeneID:913408"
     CDS             complement(15419..15628)
                     /gene="mokC"
                     /locus_tag="ECs_0016"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein MokC for HokC"
                     /protein_id="NP_308043.1"
                     /db_xref="GeneID:913408"
                     /translation="MLNTCRVPLTDRKVKEKRAMKQHKVMIVALIVICITAVVAALVT
                     RKDLCEVHIRTGQTEVAVFTAYESE"
     misc_feature    complement(15431..15553)
                     /gene="mokC"
                     /locus_tag="ECs_0016"
                     /note="Hok/gef family; Region: HOK_GEF; pfam01848"
                     /db_xref="CDD:426473"
     gene            16157..17323
                     /gene="nhaA"
                     /locus_tag="ECs_0017"
                     /db_xref="GeneID:913409"
     CDS             16157..17323
                     /gene="nhaA"
                     /locus_tag="ECs_0017"
                     /codon_start=1
                     /transl_table=11
                     /product="pH-dependent sodium/proton antiporter"
                     /protein_id="NP_308044.1"
                     /db_xref="GeneID:913409"
                     /translation="MKHLHRFFSSDASGGIILIIAAILAMMMANSGATSGWYHDFLET
                     PVQLRVGSLEINKNMLLWINDALMAVFFLLVGLEVKRELMQGSLASLRQAAFPVIAAI
                     GGMIVPALLYLAFNYADPITREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALA
                     IIDDLGAIIIIALFYTNDLSMASLGVAAVAIAVLAVLNLCGVRRTGVYILVGVVLWTA
                     VLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSL
                     QGVTLDGLTSILPLGIIAGLLIGKPLGISLFCWLALRLKLAHLPEGTTYQQIMAVGIL
                     CGIGFTMSIFIASLAFGSVDPELINWAKLGILVGSISSAVIGYSWLRVRLRPSV"
     misc_feature    16157..17320
                     /gene="nhaA"
                     /locus_tag="ECs_0017"
                     /note="sodium/proton antiporter NhaA; Region: nhaA;
                     PRK09561"
                     /db_xref="CDD:181955"
     gene            17389..18288
                     /gene="nhaR"
                     /locus_tag="ECs_0018"
                     /db_xref="GeneID:913410"
     CDS             17389..18288
                     /gene="nhaR"
                     /locus_tag="ECs_0018"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator"
                     /protein_id="NP_308045.2"
                     /db_xref="GeneID:913410"
                     /translation="MSHINYNHLYYFWHVYKEGSVVGAAEALYLTPQTITGQIRALEE
                     RLQGKLFKRKGRGLEPSELGELVYRYADKMFTLSQEMLDIVNYRKESNLLFDVGVADV
                     LSKRLVSSVLNAAVVEGEPIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQEGL
                     FSVRIGECGVSFWCTNPPPEKPFPACLEERRLLIPGRRSMLGRKLLNWFNSQGLNVEI
                     LGEFDDAALMKAFGAMHNAIFVAPTLYAYDFYADKTVVEIGRVENVMEEYHAIFAERM
                     IQHPAVQRICNTDYSALFSPAVR"
     misc_feature    17389..18276
                     /gene="nhaR"
                     /locus_tag="ECs_0018"
                     /note="transcriptional activator NhaR; Provisional;
                     Region: nhaR; PRK11062"
                     /db_xref="CDD:182938"
     gene            complement(18326..19286)
                     /locus_tag="ECs_0019"
                     /pseudogene="unknown"
                     /db_xref="GeneID:62675950"
     misc_feature    complement(18326..19286)
                     /locus_tag="ECs_0019"
                     /note="hypothetical protein"
                     /pseudogene="unknown"
     gene            complement(19299..21749)
                     /locus_tag="ECs_0022"
                     /db_xref="GeneID:913416"
     CDS             complement(19299..21749)
                     /locus_tag="ECs_0022"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial assembly protein"
                     /protein_id="NP_308049.1"
                     /db_xref="GeneID:913416"
                     /translation="MLRTTRWVAAIIFLYSFPGYAEETFDTHFMIGGMKGEKVSEYHF
                     DNKQPLPGNYELDFYVNNQWRGKQDITIPESPVKPCLPKVLLTKLGVKTGNLNTEDNC
                     ILLDKAVHGGQYQWDISEHRLNLTVPQAYINELERGYVPPESWDRGIDAFYTSYNLSQ
                     YRSYDSNNNSNTASYGRFNSGLNLFSWQLHSDASYSKPDDMKGTWQSNTLYLEHGWSQ
                     ILSTVQIGENYTSSLIFDSLRFSGIRLFRDMQMLPDSMQSFTPLVQGVAQSNALITVS
                     QNGYIIYQKEVPPGPFTIADLQLSGSGSDLDVSIKEADGSVRSFLVPYSSVPNMLQPG
                     ISNFDFIAGRSKIYGVKNQEDFLEANYIYGLNNLLTLYGGTILSDNYNAITLGNGWNT
                     PLGAISFDATRSSSKLNNDITHEGTSYQVAYNKYLVQTATRFSVAAWRYASQDYRTFS
                     DHLYENDKINHQSDYDDFYDIGRKNSLSANIMQPLSNNLGNVSLSALWRNYWGRSGNA
                     KDYQFSYSNSWQRISYTFSASQSYDENDKEEERFNLFISIPFYWGDDIAKTRHQINLS
                     NSTSFSKDGYSSNNTGITGIAGEHDQLNYGIYVNQQQQNNDTSLGTNLSWRTPIATID
                     GSYSHSKNAWQSGGSISSGLVVWPGGINITNQLSDTFAILDAPGLEGAHINGQKYNRT
                     NSKGQVVYDLMIPHRENHLVLDTANSESETELQGNRQIIAPYRGAVSYVQFTTDQRKP
                     WYIQALRPDGSPLTFGYDVLDLQENNIGVVGQGSRLFIRVDEIPTGIKVALNDEQNLF
                     CTITFQHVIDENKTYICQ"
     misc_feature    complement(19302..21749)
                     /locus_tag="ECs_0022"
                     /note="fimbrial outer membrane usher protein; Provisional;
                     Region: PRK15217"
                     /db_xref="CDD:185139"
     gene            complement(21762..22445)
                     /locus_tag="ECs_0023"
                     /db_xref="GeneID:913417"
     CDS             complement(21762..22445)
                     /locus_tag="ECs_0023"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="NP_308050.1"
                     /db_xref="GeneID:913417"
                     /translation="MRIITALLMSFFILPVHAGVVIYGTRIIYPEKNREVLVQLMNQS
                     KNASLIQAWIDDGNTTIAPEKIQVTFILTPPVSRVAGGSGQQLKIRKMPNNLPHNKES
                     LFYLNVLDIPPNNPQNAGKNKIKLALQNRIKLLWRPSGIAPVDKKSLSQLNIKKKNNA
                     ISINNETANWITVTTIKAQNVKVNNESILLPPFSHNDITLKNNHASEYELTVVDDYGN
                     NIHSKIAAR"
     misc_feature    complement(21774..22445)
                     /locus_tag="ECs_0023"
                     /note="putative fimbrial assembly chaperone protein StcB;
                     Provisional; Region: PRK15253"
                     /db_xref="CDD:185165"
     gene            complement(22495..23028)
                     /locus_tag="ECs_0024"
                     /db_xref="GeneID:913418"
     CDS             complement(22495..23028)
                     /locus_tag="ECs_0024"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="NP_308051.1"
                     /db_xref="GeneID:913418"
                     /translation="MKKYIIPFVATTLMFSATTFAKDVDQGTLTIRGEVVDTTCYFVN
                     GDSTTDIVVEDVVTSAMNQLINNEIYTLKTGSTSHDLEIQCDGNTAPSIEVLASEFDA
                     NNFTLNKGTAENIGFAIFLDDGTLTRMRPGLKTPLKDNGSGQYFLNLNAQYARTSGNP
                     VTKGSVESTVTIKISAD"
     misc_feature    complement(22498..23028)
                     /locus_tag="ECs_0024"
                     /note="Fimbrial protein; Region: Fimbrial; cl01416"
                     /db_xref="CDD:445401"
     gene            complement(23330..24751)
                     /gene="espX1"
                     /locus_tag="ECs_0025"
                     /db_xref="GeneID:913419"
     CDS             complement(23330..24751)
                     /gene="espX1"
                     /locus_tag="ECs_0025"
                     /codon_start=1
                     /transl_table=11
                     /product="T3SS effector-like protein EspX"
                     /protein_id="NP_308052.1"
                     /db_xref="GeneID:913419"
                     /translation="MTDGISTSPHCLYKSNIVDDVIINKTRQNELVKVFCEYKTEFLI
                     LFDDFFRSQDLPKPSPVLHHFFQYTHLRDAHFYRCKLIEHTVQFSFFKHKGITLLRLD
                     VFDDRTSECLSEEIKIYQECHEKFIKFLKANFNQEIYPELYTPEIFYEACRNLQSFYD
                     HQETSQNAKYSAIVKKKSYFNKEIRNLIKKNIYPELYNEQCNKIPASSTDDNQKITWQ
                     NFKTSNAAYSQLCEKLSLLKSSPSRLIEKSAYCSNENMITDKFDVVFSYCGDNVKEFI
                     LLLPYNKSLEMHELNEQNIQYLTALNINIHKLLLSNITIEKSNLSYGYYFGCVLSNIS
                     CFESDLSNTIFSNGEINNLFIKKSNIFGTSFTNTMIKNLRCEDIMPGRWTTQLVNKHL
                     GYRYTGVFKTLASIDDKPSRFEILIPLVQTLVRDNVKLNNDVYKELKKFMHDYDKTSP
                     EMRKYLQSINESMFLMKKISHQD"
     misc_feature    complement(23618..>23887)
                     /gene="espX1"
                     /locus_tag="ECs_0025"
                     /note="Uncharacterized protein YjbI, contains pentapeptide
                     repeats [Function unknown]; Region: YjbI; COG1357"
                     /db_xref="CDD:224276"
     gene            complement(25221..25484)
                     /gene="rpsT"
                     /locus_tag="ECs_0026"
                     /db_xref="GeneID:913420"
     CDS             complement(25221..25484)
                     /gene="rpsT"
                     /locus_tag="ECs_0026"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal subunit protein S20"
                     /protein_id="NP_308053.1"
                     /db_xref="GeneID:913420"
                     /translation="MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDK
                     AAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA"
     misc_feature    complement(25224..25484)
                     /gene="rpsT"
                     /locus_tag="ECs_0026"
                     /note="Ribosomal protein S20 [Translation, ribosomal
                     structure and biogenesis]; Region: RpsT; COG0268"
                     /db_xref="CDD:223346"
     gene            25819..26760
                     /gene="ribF"
                     /locus_tag="ECs_0028"
                     /db_xref="GeneID:913423"
     CDS             25819..26760
                     /gene="ribF"
                     /locus_tag="ECs_0028"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="NP_308055.1"
                     /db_xref="GeneID:913423"
                     /translation="MKLIRGIHNLSQAPQEGCVLTIGNFDGVHRGHRALLQGLQEEGR
                     KRNLPVMVMLFEPQPLELFATDKAPARLTRLREKLRYLAECGVDYVLCVRFDRRFAAL
                     TAQNFISDLLVKHLRVKFLAVGDDFRFGAGREGDFLLLQKAGMEYGFDITSTQTFCEG
                     GVRISSTAVRQALADDNLALAESLLGHPFAISGRVVHGDELGRTIGFPTANVPLRRQV
                     SPVKGVYAVEVLGLGEKPLPGVANIGTRPTVAGIRQQLEVHLLDVAMDLYGRHIQVVL
                     RKKIRNEQRFASLDELKAQIARDELTAREFFGLTKPA"
     misc_feature    25822..26745
                     /gene="ribF"
                     /locus_tag="ECs_0028"
                     /note="bifunctional riboflavin kinase/FAD synthetase;
                     Region: PRK05627"
                     /db_xref="CDD:235536"
     gene            26803..29619
                     /gene="ileS"
                     /locus_tag="ECs_0029"
                     /db_xref="GeneID:913425"
     CDS             26803..29619
                     /gene="ileS"
                     /locus_tag="ECs_0029"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucyl-tRNA synthetase"
                     /protein_id="NP_308056.1"
                     /db_xref="GeneID:913425"
                     /translation="MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAA
                     KKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPI
                     ELKVEQEYGKPDEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFK
                     TEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFQAVD
                     QDALKAKFGVSNVNGPISLVIWTTTPWTLPANRAISIAPDFDYALVQIDGQAVILAKD
                     LVESVMQRIGVTDYTILGTVKGAELELLRFAHPFMGFDVPAILGDHVTLDAGTGAVHT
                     APGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVVALLQEKGA
                     LLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQA
                     RIESMVANRPDWCISRQRTWGVPMSLFVHKDTEELHPRTLELMEEVAKRVEVDGIQAW
                     WDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVVDVRPEFAGHAADMYLEGSDQH
                     RGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADI
                     LRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMV
                     VLDRWAVGCAKAAQEDILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKA
                     DSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFTGEWYEGLFGL
                     ADSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYTEPELAAKLTALG
                     DELRFVLLTSGATVADYNDAPADAQQSEVLKGLKVALSKAEGEKCPRCWHYTQDVGKV
                     AEHAEICGRCVSNVAGDGEKRKFA"
     misc_feature    26806..29598
                     /gene="ileS"
                     /locus_tag="ECs_0029"
                     /note="Isoleucyl-tRNA synthetase [Translation, ribosomal
                     structure and biogenesis]; Region: IleS; COG0060"
                     /db_xref="CDD:223138"
     gene            29619..30113
                     /gene="lspA"
                     /locus_tag="ECs_0030"
                     /db_xref="GeneID:913426"
     CDS             29619..30113
                     /gene="lspA"
                     /locus_tag="ECs_0030"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein signal peptidase"
                     /protein_id="NP_308057.1"
                     /db_xref="GeneID:913426"
                     /translation="MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFP
                     SLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVTLVVMMYRSKATQKLNNIAYA
                     LIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSK
                     AKKQ"
     misc_feature    29622..30098
                     /gene="lspA"
                     /locus_tag="ECs_0030"
                     /note="lipoprotein signal peptidase; Region: lspA;
                     PRK00376"
                     /db_xref="CDD:234739"
     gene            30201..30650
                     /gene="fkpB"
                     /locus_tag="ECs_0031"
                     /db_xref="GeneID:913427"
     CDS             30201..30650
                     /gene="fkpB"
                     /locus_tag="ECs_0031"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="NP_308058.1"
                     /db_xref="GeneID:913427"
                     /translation="MSESVQSNSAVLVHFTLKLDDGTTAESTRNNGKPALFRLGDASL
                     SEGLEQHLLGLKVGDKTTFSLEPDAAFGVPSPDLIQYFSRREFMDAGEPEIGAIMLFT
                     AMDGSEMPGVIREINGDSITVDFNHPLAGQTVHFDIEVLEIDPALEA"
     misc_feature    30201..30647
                     /gene="fkpB"
                     /locus_tag="ECs_0031"
                     /note="FKBP-type peptidyl-prolyl cis-trans isomerase;
                     Provisional; Region: PRK15095"
                     /db_xref="CDD:237908"
     gene            30652..31602
                     /gene="ispH"
                     /locus_tag="ECs_0032"
                     /db_xref="GeneID:913428"
     CDS             30652..31602
                     /gene="ispH"
                     /locus_tag="ECs_0032"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="NP_308059.1"
                     /db_xref="GeneID:913428"
                     /translation="MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRY
                     VVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKV
                     HMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEK
                     LSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVL
                     VVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQ
                     NVVARLQQLGGGEAIPLEGREENIVFEVPKELRVDIREVD"
     misc_feature    30652..31554
                     /gene="ispH"
                     /locus_tag="ECs_0032"
                     /note="4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
                     Reviewed; Region: ispH; PRK01045"
                     /db_xref="CDD:234893"
     misc_feature    order(30685..30687,30937..30939,31240..31242)
                     /gene="ispH"
                     /locus_tag="ECs_0032"
                     /note="Fe-S cluster binding site [ion binding]; other
                     site"
                     /db_xref="CDD:260116"
     misc_feature    order(30694..30696,30769..30774,30868..30873,31021..31023,
                     31027..31029,31150..31155,31321..31332,31456..31458)
                     /gene="ispH"
                     /locus_tag="ECs_0032"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:260116"
     misc_feature    order(31021..31023,31027..31029,31324..31326,31330..31332)
                     /gene="ispH"
                     /locus_tag="ECs_0032"
                     /note="catalytic site [active]"
                     /db_xref="CDD:260116"
     gene            31668..32582
                     /gene="rihC"
                     /locus_tag="ECs_0033"
                     /db_xref="GeneID:913429"
     CDS             31668..32582
                     /gene="rihC"
                     /locus_tag="ECs_0033"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside hydrolase 3"
                     /protein_id="NP_308060.1"
                     /db_xref="GeneID:913429"
                     /translation="MRLPIFLDTDPGIDDAVAIAAAIFAPELDLQLMTTVAGNVSVEK
                     TTRNALQLLHFWNAEIPLAQGAAVPLVRAPRDAASVHGESGMAGYDFVEHNRKPLGIP
                     AFLAIRDALMRAPEPVTLVAIGPLTNIALLLSQCPECKPYIRRLVIMGGSAGRGNCTP
                     NAEFNIAADPEAAACVFRSGIEIVMCGLDVTNQAILTPDYLSTLPQLNRTGKMLHALF
                     SHYRSGSMQSGLRMHDLCAIAWLVRPDLFTLKPCFVAVETQGEFTSGTTVVDIDGCLG
                     KPANVQVALDLNVKGFQQWVAEVLALVP"
     misc_feature    31668..32579
                     /gene="rihC"
                     /locus_tag="ECs_0033"
                     /note="ribonucleoside hydrolase RihC; Provisional; Region:
                     PRK10768"
                     /db_xref="CDD:182713"
     misc_feature    order(31695..31697,31707..31712,31782..31784,31905..31907,
                     32034..32036,32136..32138,32154..32156,32160..32162,
                     32367..32369)
                     /gene="rihC"
                     /locus_tag="ECs_0033"
                     /note="active site"
                     /db_xref="CDD:239117"
     misc_feature    order(31875..31877,32067..32069,32190..32192,32436..32438,
                     32442..32447,32454..32456)
                     /gene="rihC"
                     /locus_tag="ECs_0033"
                     /note="tetramer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:239117"
     gene            32749..33570
                     /gene="dapB"
                     /locus_tag="ECs_0034"
                     /db_xref="GeneID:913430"
     CDS             32749..33570
                     /gene="dapB"
                     /locus_tag="ECs_0034"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
                     /protein_id="NP_308061.1"
                     /db_xref="GeneID:913430"
                     /translation="MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSL
                     LGSDAGELAGAGKTGVTVQSSLDAIKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIG
                     TTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHH
                     RHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVG
                     EHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSGKENGLFDMRDVLDLNNL"
     misc_feature    32764..33558
                     /gene="dapB"
                     /locus_tag="ECs_0034"
                     /note="Dihydrodipicolinate reductase [Amino acid transport
                     and metabolism]; Region: DapB; COG0289"
                     /db_xref="CDD:223366"
     gene            34026..35174
                     /gene="carA"
                     /locus_tag="ECs_0035"
                     /db_xref="GeneID:913431"
     CDS             34026..35174
                     /gene="carA"
                     /locus_tag="ECs_0035"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthetase small subunit"
                     /protein_id="NP_308062.1"
                     /db_xref="GeneID:913431"
                     /translation="MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILT
                     DPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYL
                     KRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAK
                     EVTTAEAYSWTQGSWTLTGGLPEAKKEDELPFHVVAYDFGAKRNILRMLVDRGCRLTI
                     VPAQTSAEDVLKMNPDGIFLSNGPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLA
                     LASGAKTVKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEATLPANLRVTHKSLFD
                     GTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIELIEQYRKTAK"
     misc_feature    34026..35147
                     /gene="carA"
                     /locus_tag="ECs_0035"
                     /note="carbamoyl-phosphate synthase small subunit; Region:
                     PRK12564"
                     /db_xref="CDD:237139"
     gene            35192..38413
                     /gene="carB"
                     /locus_tag="ECs_0036"
                     /db_xref="GeneID:913432"
     CDS             35192..38413
                     /gene="carB"
                     /locus_tag="ECs_0036"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="NP_308063.1"
                     /db_xref="GeneID:913432"
                     /translation="MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRV
                     ILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALEL
                     ERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHTMEEALAVAA
                     DVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEM
                     EVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIG
                     VETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDE
                     LMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQ
                     ESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGAERIWYIADAFRAGLSVD
                     GVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLNAEFLRQLKRKGFADARLAKLAGV
                     REAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECEANPSTDREKIMVLG
                     GGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLE
                     DVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAV
                     DRLKLKQPANATVTAIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQT
                     AVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPA
                     YTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKA
                     TGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRST
                     GEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELD
                     ATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIR
                     RSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK"
     misc_feature    35192..38398
                     /gene="carB"
                     /locus_tag="ECs_0036"
                     /note="carbamoyl-phosphate synthase large subunit; Region:
                     carB; PRK05294"
                     /db_xref="CDD:235393"
     gene            complement(38421..38639)
                     /locus_tag="ECs_5362"
                     /db_xref="GeneID:62675951"
     CDS             complement(38421..38639)
                     /locus_tag="ECs_5362"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_009502587.1"
                     /db_xref="GeneID:62675951"
                     /translation="MTRFEAIKQGHIKIVDISIVCNFTVDKCELNPAYVIKNIDSPKD
                     LLNGQKKRSSSENRISYSIKLADEKYPP"
     gene            38674..39069
                     /gene="caiF"
                     /locus_tag="ECs_0037"
                     /db_xref="GeneID:913433"
     CDS             38674..39069
                     /gene="caiF"
                     /locus_tag="ECs_0037"
                     /codon_start=1
                     /transl_table=11
                     /product="cai operon transcriptional activator"
                     /protein_id="NP_308064.2"
                     /db_xref="GeneID:913433"
                     /translation="MCEGYVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNT
                     LTYILSEVTEISCEVKMIPNKLEGRGCQCQRLVKVVDIDEQIYARLRNNSREKLVGVR
                     KTPRIPAVPLTELNREQKWQMMLSKSMRR"
     misc_feature    38728..39066
                     /gene="caiF"
                     /locus_tag="ECs_0037"
                     /note="carnitine metabolism transcriptional regulator
                     CaiF; Region: PRK11476"
                     /db_xref="CDD:183154"
     gene            complement(39188..39778)
                     /gene="caiE"
                     /locus_tag="ECs_0038"
                     /db_xref="GeneID:913434"
     CDS             complement(39188..39778)
                     /gene="caiE"
                     /locus_tag="ECs_0038"
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine operon protein CaiE"
                     /protein_id="NP_308065.2"
                     /db_xref="GeneID:913434"
                     /translation="MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLR
                     GDYGRLIVQAGANIQDGCIMHGYTDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSV
                     IMDGAVIGEESIVAAMSFVKAGFHGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQ
                     DLVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR"
     misc_feature    complement(39191..39778)
                     /gene="caiE"
                     /locus_tag="ECs_0038"
                     /note="carnitine operon protein CaiE; Provisional; Region:
                     PRK13627"
                     /db_xref="CDD:184189"
     gene            complement(39784..40569)
                     /gene="caiD"
                     /locus_tag="ECs_0039"
                     /db_xref="GeneID:913435"
     CDS             complement(39784..40569)
                     /gene="caiD"
                     /locus_tag="ECs_0039"
                     /codon_start=1
                     /transl_table=11
                     /product="carnitinyl-CoA dehydratase"
                     /protein_id="NP_308066.2"
                     /db_xref="GeneID:913435"
                     /translation="MSESLHLTRNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDD
                     PQLRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVN
                     GYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVM
                     TGRRMGAEEALRWGIVNRVVSQAELMDNARELAQQLVNSAPLAIAALKEIYRTTSEMP
                     VEESYSYIRSGVLKHYPSVLHSEDAIEGPLAFAEKRDPVWKGR"
     misc_feature    complement(39787..40569)
                     /gene="caiD"
                     /locus_tag="ECs_0039"
                     /note="crotonobetainyl-CoA hydratase; Region: PRK03580"
                     /db_xref="CDD:179599"
     misc_feature    complement(order(40168..40170,40177..40182,40246..40254,
                     40258..40260,40372..40386,40396..40398,40495..40497,
                     40501..40503))
                     /gene="caiD"
                     /locus_tag="ECs_0039"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:119339"
     misc_feature    complement(order(40246..40248,40378..40380))
                     /gene="caiD"
                     /locus_tag="ECs_0039"
                     /note="oxyanion hole (OAH) forming residues [active]"
                     /db_xref="CDD:119339"
     misc_feature    complement(order(39982..39987,39994..39996,40039..40041,
                     40048..40050,40081..40083,40090..40095,40099..40104,
                     40108..40113,40126..40131,40135..40143,40147..40149,
                     40165..40176,40210..40221,40282..40284,40306..40308))
                     /gene="caiD"
                     /locus_tag="ECs_0039"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119339"
     gene            complement(40678..42231)
                     /gene="caiC"
                     /locus_tag="ECs_0040"
                     /db_xref="GeneID:913437"
     CDS             complement(40678..42231)
                     /gene="caiC"
                     /locus_tag="ECs_0040"
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetaine/carnitine-CoA ligase"
                     /protein_id="NP_308067.2"
                     /db_xref="GeneID:913437"
                     /translation="MDIIGGQHLRQMWDDLADVYGHKTALICESSGGVVNRYSYLELN
                     QEINRTANLFYTLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREESA
                     WILQNSQACLLVTSAQFYPMYQQIQQEDATQLRHICLTDVALPADDGVSSFTQLKNQQ
                     PATLCYAPPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRDDDVYL
                     TVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSARAFWGQVQKYRATITECIPMMIRTL
                     MVQPPSANDRQHRLREVMFYLNLSEQEKDTFCERFGVRLLTSYGMTETIVGIIGDRPG
                     DKRRWPSIGRAGFCYDAEIRDDHNRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAK
                     VLEADGWLHTGDTGYRDEEGFFYFIDRRCNMIKRGGENVSCVELENIIATHPKIQDIV
                     VVGIKDSIRDEAIKAFVVLNEGETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCS
                     GKIIRKNLK"
     misc_feature    complement(40681..42231)
                     /gene="caiC"
                     /locus_tag="ECs_0040"
                     /note="putative crotonobetaine/carnitine-CoA ligase;
                     Validated; Region: caiC; PRK08008"
                     /db_xref="CDD:181195"
     gene            complement(42305..43522)
                     /gene="caiB"
                     /locus_tag="ECs_0041"
                     /db_xref="GeneID:913438"
     CDS             complement(42305..43522)
                     /gene="caiB"
                     /locus_tag="ECs_0041"
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl CoA:carnitine CoA transferase"
                     /protein_id="NP_308068.1"
                     /db_xref="GeneID:913438"
                     /translation="MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIE
                     NVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFA
                     RRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQP
                     MPAFPYTADYFSGLTATTAALAALHKARETGKGESIDIAMYEVMLRMGQYFMMDYFNG
                     GEMCPRMSKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLGTPEIPE
                     GTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACAKVLTVPELESNPQY
                     VARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDI
                     QELVSKGLAKVED"
     misc_feature    complement(42308..43522)
                     /gene="caiB"
                     /locus_tag="ECs_0041"
                     /note="L-carnitine CoA-transferase; Region: PRK03525"
                     /db_xref="CDD:179589"
     gene            complement(43651..44793)
                     /gene="caiA"
                     /locus_tag="ECs_0042"
                     /db_xref="GeneID:913439"
     CDS             complement(43651..44793)
                     /gene="caiA"
                     /locus_tag="ECs_0042"
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetaine reductase subunit II"
                     /protein_id="NP_308069.1"
                     /db_xref="GeneID:913439"
                     /translation="MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVK
                     ALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGT
                     QEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSA
                     YTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELD
                     EKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRF
                     QLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQ
                     VLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR"
     misc_feature    complement(43654..44793)
                     /gene="caiA"
                     /locus_tag="ECs_0042"
                     /note="crotonobetainyl-CoA dehydrogenase; Validated;
                     Region: PRK03354"
                     /db_xref="CDD:179566"
     gene            complement(44824..46338)
                     /gene="caiT"
                     /locus_tag="ECs_0043"
                     /db_xref="GeneID:913440"
     CDS             complement(44824..46338)
                     /gene="caiT"
                     /locus_tag="ECs_0043"
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="NP_308070.1"
                     /db_xref="GeneID:913440"
                     /translation="MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVF
                     SYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSA
                     AVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFLWGPLPWATYSFLSVAFAYF
                     FFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTEC
                     MQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIV
                     SGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIF
                     LARISRGRTVRELCFGMVMGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVAR
                     AIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRI
                     GWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD"
     misc_feature    complement(44827..46338)
                     /gene="caiT"
                     /locus_tag="ECs_0043"
                     /note="L-carnitine/gamma-butyrobetaine antiport BCCT
                     transporter; Region: PRK03356"
                     /db_xref="CDD:179568"
     gene            46817..47587
                     /gene="fixA"
                     /locus_tag="ECs_0044"
                     /db_xref="GeneID:913441"
     CDS             46817..47587
                     /gene="fixA"
                     /locus_tag="ECs_0044"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carnitine reduction electron transfer
                     flavoprotein subunit"
                     /protein_id="NP_308071.2"
                     /db_xref="GeneID:913441"
                     /translation="MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEA
                     ACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTAS
                     ALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVE
                     RELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAA
                     WSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI"
     misc_feature    46817..47584
                     /gene="fixA"
                     /locus_tag="ECs_0044"
                     /note="putative electron transfer flavoprotein FixA;
                     Reviewed; Region: PRK03359"
                     /db_xref="CDD:179569"
     misc_feature    order(46832..46837,46919..46921,46928..46930,47000..47002,
                     47168..47173,47177..47182,47195..47206)
                     /gene="fixA"
                     /locus_tag="ECs_0044"
                     /note="Ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:238847"
     gene            47602..48543
                     /gene="fixB"
                     /locus_tag="ECs_0045"
                     /db_xref="GeneID:913442"
     CDS             47602..48543
                     /gene="fixB"
                     /locus_tag="ECs_0045"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein FixB"
                     /protein_id="NP_308072.1"
                     /db_xref="GeneID:913442"
                     /translation="MNTFSQVWVFSDTPSRLPELMNGAQALANQINAFVLNDADGAQA
                     IQLGANHVWKLNGKPDDRMIEDYASVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYR
                     LKAAVSNDASTVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDAS
                     RTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLC
                     KAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQT
                     IFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR"
     misc_feature    47602..48540
                     /gene="fixB"
                     /locus_tag="ECs_0045"
                     /note="electron transfer flavoprotein subunit alpha/FixB
                     family protein; Region: fixB; PRK03363"
                     /db_xref="CDD:235120"
     gene            48594..49880
                     /gene="ydiS"
                     /locus_tag="ECs_0046"
                     /db_xref="GeneID:913445"
     CDS             48594..49880
                     /gene="ydiS"
                     /locus_tag="ECs_0046"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="NP_308073.1"
                     /db_xref="GeneID:913445"
                     /translation="MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKN
                     VTGGRLYAHSLEHIIPGFAESAPVERLITHEKLAFMTEKSAMTMDYCNGDETSPSQRS
                     YSVLRSKFDAWLMEQAEEAGAQLITGIRVDNLVQRDGKVVGVEADGDVIEAKTVILAD
                     GVNSILAEKLGMAKRVKPTNVAVGVKELIELPKSVIEDRFQLQGNQGAACLFAGSPTD
                     GLMGGGFLYTNENTLSLGLVCGLHHLHDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEY
                     SAHVVPEAGINMLPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAIAAGEAAAKTVLSA
                     MKSDDFSKQKLAEYRQHLESGPLRDMRMYQKLPAFLDNPRMFSGYPELAVGVARDLFT
                     IDGSAPELMRKKILRHGKKVGFINLIKDGMKGVTVL"
     misc_feature    48594..49877
                     /gene="ydiS"
                     /locus_tag="ECs_0046"
                     /note="putative oxidoreductase FixC; Provisional; Region:
                     PRK10157"
                     /db_xref="CDD:182273"
     gene            49877..50164
                     /gene="fixX"
                     /locus_tag="ECs_0047"
                     /db_xref="GeneID:913446"
     CDS             49877..50164
                     /gene="fixX"
                     /locus_tag="ECs_0047"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="NP_308074.1"
                     /db_xref="GeneID:913446"
                     /translation="MTSPVNVDVKLGVNKFNVDEEHPHIVVKADADKQALELLVKACP
                     AGLYKKQDDGSVRFDYAGCLECGTCRILGLGSALEQWEYPRGTFGVEFRYG"
     misc_feature    49877..50161
                     /gene="fixX"
                     /locus_tag="ECs_0047"
                     /note="ferredoxin-like protein FixX; Provisional; Region:
                     PRK15449"
                     /db_xref="CDD:185346"
     gene            50222..51553
                     /gene="yaaU"
                     /locus_tag="ECs_0048"
                     /db_xref="GeneID:913447"
     CDS             50222..51553
                     /gene="yaaU"
                     /locus_tag="ECs_0048"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS sugar transporter"
                     /protein_id="NP_308075.1"
                     /db_xref="GeneID:913447"
                     /translation="MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYILVMIGVALEQL
                     TPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMF
                     VSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
                     VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFG
                     EPVAFDEEQPQQTRFRDLFNRRHFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLG
                     VGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGI
                     WLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPI
                     FINNYGISNTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG"
     misc_feature    50279..51475
                     /gene="yaaU"
                     /locus_tag="ECs_0048"
                     /note="Metazoan Synaptic vesicle glycoprotein 2 (SV2) and
                     related small molecule transporters of the Major
                     Facilitator Superfamily; Region: MFS_SV2_like; cd17316"
                     /db_xref="CDD:340874"
     misc_feature    order(50309..50314,50321..50326,50333..50335,50429..50431,
                     50579..50584,50588..50596,50603..50605,50663..50665,
                     50672..50677,50684..50686,50975..50977,50984..50989,
                     50996..51004,51011..51013,51095..51097,51107..51109,
                     51260..51265,51275..51277,51287..51289,51335..51337,
                     51344..51349,51356..51361,51368..51370)
                     /gene="yaaU"
                     /locus_tag="ECs_0048"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]; other site"
                     /db_xref="CDD:340874"
     gene            51661..52191
                     /gene="kefF"
                     /locus_tag="ECs_0049"
                     /db_xref="GeneID:913448"
     CDS             51661..52191
                     /gene="kefF"
                     /locus_tag="ECs_0049"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter"
                     /protein_id="NP_308076.1"
                     /db_xref="GeneID:913448"
                     /translation="MILIIYAHPYPHHSHANKRMFEQARTLEGVEIRSLYQLYPDFNI
                     DIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLW
                     AVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQA
                     RHYKQRLLEWQEAHHG"
     misc_feature    51661..52188
                     /gene="kefF"
                     /locus_tag="ECs_0049"
                     /note="glutathione-regulated potassium-efflux system
                     oxidoreductase KefF; Region: PRK00871"
                     /db_xref="CDD:234852"
     gene            52184..54046
                     /gene="kefC"
                     /locus_tag="ECs_0050"
                     /db_xref="GeneID:913449"
     CDS             52184..54046
                     /gene="kefC"
                     /locus_tag="ECs_0050"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein"
                     /protein_id="NP_308077.1"
                     /db_xref="GeneID:913449"
                     /translation="MDSHTLVQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPW
                     GLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLG
                     LFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAI
                     PLVAMIPLLAASSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREV
                     FSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLF
                     FIGVGMSIDFGTLIENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQ
                     GSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREA
                     DEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDA
                     TRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYICLRQ
                     AGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTK
                     ARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS"
     misc_feature    52184..54043
                     /gene="kefC"
                     /locus_tag="ECs_0050"
                     /note="glutathione-regulated potassium-efflux system
                     protein KefC; Provisional; Region: PRK03562"
                     /db_xref="CDD:235131"
     gene            54127..54717
                     /gene="folA"
                     /locus_tag="ECs_0051"
                     /db_xref="GeneID:913450"
     CDS             54127..54717
                     /gene="folA"
                     /locus_tag="ECs_0051"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="NP_308078.2"
                     /db_xref="GeneID:913450"
                     /translation="MDSPAEYKIFLNIILAPVDDGLRFTYSGDNFFYREISMISLIAA
                     LAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTRESIGRPLPGRKNIILSSQ
                     PGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDT
                     HFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR"
     misc_feature    54238..54714
                     /gene="folA"
                     /locus_tag="ECs_0051"
                     /note="type 3 dihydrofolate reductase; Region: folA;
                     PRK10769"
                     /db_xref="CDD:182714"
     misc_feature    order(54250..54252,54301..54303,54316..54318,54406..54408,
                     54517..54519,54535..54537,54574..54576)
                     /gene="folA"
                     /locus_tag="ECs_0051"
                     /note="folate binding site [chemical binding]; other site"
                     /db_xref="CDD:238127"
     misc_feature    order(54256..54258,54277..54279,54367..54375,54427..54429,
                     54520..54531)
                     /gene="folA"
                     /locus_tag="ECs_0051"
                     /note="NADP+ binding site [chemical binding]; other site"
                     /db_xref="CDD:238127"
     gene            54803..55036
                     /locus_tag="ECs_0052"
                     /db_xref="GeneID:913451"
     CDS             54803..55036
                     /locus_tag="ECs_0052"
                     /codon_start=1
                     /transl_table=11
                     /product="CcdA-like protein"
                     /protein_id="NP_308079.1"
                     /db_xref="GeneID:913451"
                     /translation="MTAKRTTQSVTVTVDRELVNRARDAGLNMSATLTVALNAELKKH
                     AATRWREENAEAIAALNQLADETGCFSDEYRSF"
     misc_feature    54803..55033
                     /locus_tag="ECs_0052"
                     /note="Post-segregation antitoxin (ccd killing mechanism
                     protein) encoded by the F plasmid [Mobilome: prophages,
                     transposons]; Region: COG5302"
                     /db_xref="CDD:227619"
     gene            55039..55353
                     /locus_tag="ECs_0053"
                     /db_xref="GeneID:913452"
     CDS             55039..55353
                     /locus_tag="ECs_0053"
                     /codon_start=1
                     /transl_table=11
                     /product="CcdB-like protein"
                     /protein_id="NP_308080.1"
                     /db_xref="GeneID:913452"
                     /translation="MQFTVYRSRSRNAAFPFVIDVTSDIIGVINRRIVIPLTPIERFS
                     RIRPPERLNPILLLVDGKEYVLMTHETATVPVNALGTKFCDASAHRTLIKGALDFMLD
                     GI"
     misc_feature    55042..55344
                     /locus_tag="ECs_0053"
                     /note="CcdB protein; Region: CcdB; pfam01845"
                     /db_xref="CDD:426470"
     gene            complement(55350..56198)
                     /gene="apaH"
                     /locus_tag="ECs_0054"
                     /db_xref="GeneID:913453"
     CDS             complement(55350..56198)
                     /gene="apaH"
                     /locus_tag="ECs_0054"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenosine tetraphosphatase"
                     /protein_id="NP_308081.1"
                     /db_xref="GeneID:913453"
                     /translation="MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPG
                     SLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWL
                     RRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMP
                     NNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVA
                     EEYSIAFGHWASLEGKGTPEGIYALDTGCCWGGSLTCLRWEDKQYFVQPSNRHKDLGE
                     GEAVAS"
     misc_feature    complement(55362..56198)
                     /gene="apaH"
                     /locus_tag="ECs_0054"
                     /note="bis(5'-nucleosyl)-tetraphosphatase (symmetrical);
                     Region: apaH; TIGR00668"
                     /db_xref="CDD:273208"
     gene            complement(56205..56582)
                     /gene="apaG"
                     /locus_tag="ECs_0055"
                     /db_xref="GeneID:913454"
     CDS             complement(56205..56582)
                     /gene="apaG"
                     /locus_tag="ECs_0055"
                     /codon_start=1
                     /transl_table=11
                     /product="CO2+/MG2+ efflux protein ApaG"
                     /protein_id="NP_308082.1"
                     /db_xref="GeneID:913454"
                     /translation="MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQ
                     LLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMI
                     DENGVPFSIDIPVFRLAVPTLIH"
     misc_feature    complement(56208..56582)
                     /gene="apaG"
                     /locus_tag="ECs_0055"
                     /note="CO2+/MG2+ efflux protein ApaG; Reviewed; Region:
                     apaG; PRK05461"
                     /db_xref="CDD:180098"
     gene            complement(56585..57406)
                     /gene="rsmA"
                     /locus_tag="ECs_0056"
                     /db_xref="GeneID:913455"
     CDS             complement(56585..57406)
                     /gene="rsmA"
                     /locus_tag="ECs_0056"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal RNA small subunit methyltransferase A"
                     /protein_id="NP_308083.1"
                     /db_xref="GeneID:913455"
                     /translation="MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEI
                     GPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAE
                     KMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRL
                     SVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAF
                     NQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPFQES"
     misc_feature    complement(56600..57376)
                     /gene="rsmA"
                     /locus_tag="ECs_0056"
                     /note="16S rRNA A1518 and A1519 N6-dimethyltransferase
                     RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase
                     activity) [Translation, ribosomal structure and
                     biogenesis]; Region: RsmA; COG0030"
                     /db_xref="CDD:223109"
     gene            complement(57403..58392)
                     /gene="pdxA"
                     /locus_tag="ECs_0057"
                     /db_xref="GeneID:913457"
     CDS             complement(57403..58392)
                     /gene="pdxA"
                     /locus_tag="ECs_0057"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-L-threonine phosphate dehydrogenase"
                     /protein_id="NP_308084.1"
                     /db_xref="GeneID:913457"
                     /translation="MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLT
                     DRAAMLGLPLTLRPYSPNSPAQPQTTGTLTLLPVALRESVTAGQLAIENGHYVVETLA
                     RACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRV
                     ALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHM
                     GTEEIDTIIPVLDELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQ
                     GFGRGVNITLGLPFIRTSVDHGTALELAGRGEADVGSFITALNLAIKMIVNTQ"
     misc_feature    complement(57406..58392)
                     /gene="pdxA"
                     /locus_tag="ECs_0057"
                     /note="4-hydroxythreonine-4-phosphate dehydrogenase;
                     Reviewed; Region: pdxA; PRK00232"
                     /db_xref="CDD:234696"
     gene            complement(58392..59678)
                     /gene="surA"
                     /locus_tag="ECs_0058"
                     /db_xref="GeneID:913458"
     CDS             complement(58392..59678)
                     /gene="surA"
                     /locus_tag="ECs_0058"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="NP_308085.1"
                     /db_xref="GeneID:913458"
                     /translation="MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDG
                     LMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIAN
                     IAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESL
                     AQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIA
                     HSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGE
                     SKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGS
                     ANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAA
                     QKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN"
     misc_feature    complement(58395..59624)
                     /gene="surA"
                     /locus_tag="ECs_0058"
                     /note="peptidyl-prolyl cis-trans isomerase SurA;
                     Provisional; Region: PRK10770"
                     /db_xref="CDD:236758"
     gene            complement(59731..62085)
                     /gene="lptD"
                     /locus_tag="ECs_0059"
                     /db_xref="GeneID:913459"
     CDS             complement(59731..62085)
                     /gene="lptD"
                     /locus_tag="ECs_0059"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly OM complex LptDE beta-barrel
                     component"
                     /protein_id="NP_308086.1"
                     /db_xref="GeneID:913459"
                     /translation="MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQ
                     GDTNDLPVTINANHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVR
                     TVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGEN
                     RYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVSIFYSPYLQL
                     PVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEF
                     RYLSQAGAGLMELDYLPSDKVYEDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKV
                     SDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEP
                     QLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTE
                     AKLLATHYQQTNLDWYNSRNTTKLDESVNRVMPQFKVDGKMVFERDMEMLAPGYTQTL
                     EPRAQYLYVPYRDQSDIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRI
                     YDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISERWGLRG
                     GIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGI
                     SQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWD
                     NDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL"
     misc_feature    complement(59740..62085)
                     /gene="lptD"
                     /locus_tag="ECs_0059"
                     /note="LPS assembly outer membrane complex protein LptD;
                     Provisional; Region: PRK03761"
                     /db_xref="CDD:235158"
     gene            62340..63155
                     /gene="djlA"
                     /locus_tag="ECs_0060"
                     /db_xref="GeneID:913460"
     CDS             62340..63155
                     /gene="djlA"
                     /locus_tag="ECs_0060"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-anchored DnaK co-chaperone"
                     /protein_id="NP_308087.1"
                     /db_xref="GeneID:913460"
                     /translation="MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWF
                     ANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFR
                     VGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEE
                     LGISRAQFDQFLRMMQGGAQFGGGYQQQSGGGNWQQAQRGPTLEDACNVLGVKPTDDA
                     TTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK"
     misc_feature    62340..63152
                     /gene="djlA"
                     /locus_tag="ECs_0060"
                     /note="co-chaperone DjlA; Region: djlA; PRK09430"
                     /db_xref="CDD:236512"
     gene            63450..64202
                     /gene="espY1"
                     /locus_tag="ECs_0061"
                     /db_xref="GeneID:913461"
     CDS             63450..64202
                     /gene="espY1"
                     /locus_tag="ECs_0061"
                     /codon_start=1
                     /transl_table=11
                     /product="T3SS effector-like protein EspY"
                     /protein_id="NP_308088.1"
                     /db_xref="GeneID:913461"
                     /translation="MKVSVPGMPATLLNMSNNDIYKMVSGDKMDMKMNIFQRLWETLR
                     HLFWSDKQTEAYKLLFNFVNKKAGNINASKYFTGAVNENEKEKFIHSLELFNELKTCA
                     KNPDEMVAKGNMSWVAQTFGDIELSVTFFIENKEICTQTLQLHKGPGNLGVDLREAYL
                     PGVDMRDCYLGLKTMKGHNKVLYLEPGWNANLDGATLDGATLDGATVDGATHLYDEVI
                     IINKITPKKIDTEEVATKQSTAEQITDNAIIE"
     gene            complement(64620..65279)
                     /gene="rluA"
                     /locus_tag="ECs_0062"
                     /db_xref="GeneID:913462"
     CDS             complement(64620..65279)
                     /gene="rluA"
                     /locus_tag="ECs_0062"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA/tRNA pseudouridine synthase A"
                     /protein_id="NP_308089.1"
                     /db_xref="GeneID:913462"
                     /translation="MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKD
                     SVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWG
                     HPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGR
                     SHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAD
                     F"
     misc_feature    complement(64623..65279)
                     /gene="rluA"
                     /locus_tag="ECs_0062"
                     /note="bifunctional tRNA pseudouridine(32) synthase/23S
                     rRNA pseudouridine(746) synthase RluA; Region: PRK10158"
                     /db_xref="CDD:236659"
     misc_feature    complement(order(64785..64787,65088..65099))
                     /gene="rluA"
                     /locus_tag="ECs_0062"
                     /note="active site"
                     /db_xref="CDD:211346"
     gene            complement(65291..68197)
                     /gene="rapA"
                     /locus_tag="ECs_0063"
                     /db_xref="GeneID:913463"
     CDS             complement(65291..68197)
                     /gene="rapA"
                     /locus_tag="ECs_0063"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase remodeling/recycling factor
                     ATPase"
                     /protein_id="NP_308090.1"
                     /db_xref="GeneID:913463"
                     /translation="MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYA
                     RSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFL
                     DSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLN
                     IAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVE
                     MLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDL
                     LVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPN
                     RFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSD
                     SEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKV
                     SGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLV
                     ICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIG
                     SEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRW
                     YHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLE
                     QGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVL
                     TPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGS
                     STISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQV
                     EFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKL
                     SAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ"
     misc_feature    complement(65300..68194)
                     /gene="rapA"
                     /locus_tag="ECs_0063"
                     /note="RNA polymerase-associated protein RapA; Region:
                     PRK04914"
                     /db_xref="CDD:235319"
     gene            complement(68361..70712)
                     /gene="polB"
                     /locus_tag="ECs_0064"
                     /db_xref="GeneID:913464"
     CDS             complement(68361..70712)
                     /gene="polB"
                     /locus_tag="ECs_0064"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase II"
                     /protein_id="NP_308091.1"
                     /db_xref="GeneID:913464"
                     /translation="MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAF
                     IPADQVPRAQHILRGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVT
                     VYEADVRPPERYLMERFITSPVWVEGDMHNGAIVNARLKPHPDYRPPLKWVSIDIETT
                     RHGELYCIGLEGCGQRIVYMLGPENGDASALDFELEYVASRPQLLEKLNAWFANYDPD
                     VIIGWNVVQFDLRMLQKHAERYRIPLRLGRDNSELEWREHGFKNGVFFAQAKGRLIID
                     GIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLK
                     DCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLG
                     EVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHS
                     TEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTAC
                     RFFDPRLVSSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTFVWLKGAHSEEEATKIG
                     RALVQHVNVWWAETLQKQQLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEG
                     DKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYFRETIDKLMAGELDARL
                     VYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQYQNRGTIKYVWTTNGPEPL
                     DYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF"
     misc_feature    complement(68364..70712)
                     /gene="polB"
                     /locus_tag="ECs_0064"
                     /note="DNA polymerase II; Reviewed; Region: PRK05762"
                     /db_xref="CDD:235595"
     gene            complement(70787..71482)
                     /gene="araD"
                     /locus_tag="ECs_0065"
                     /db_xref="GeneID:913465"
     CDS             complement(70787..71482)
                     /gene="araD"
                     /locus_tag="ECs_0065"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="NP_308092.1"
                     /db_xref="GeneID:913465"
                     /translation="MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPS
                     GVDYSIMTADDMVVVSIETGEVVEGAKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHAT
                     IWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDA
                     AQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKH
                     YLRKHGAKAYYGQ"
     misc_feature    complement(70790..71482)
                     /gene="araD"
                     /locus_tag="ECs_0065"
                     /note="L-ribulose-5-phosphate 4-epimerase AraD; Region:
                     araD; PRK08193"
                     /db_xref="CDD:236181"
     misc_feature    complement(order(70826..70828,70886..70888,70907..70909,
                     70919..70921,70940..70942,70973..70975,71090..71092,
                     71132..71137,71141..71143,71162..71170,71183..71188,
                     71192..71194,71333..71338,71342..71344,71414..71416,
                     71438..71440,71450..71452))
                     /gene="araD"
                     /locus_tag="ECs_0065"
                     /note="intersubunit interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238232"
     misc_feature    complement(order(70970..70972,71192..71194,71198..71200,
                     71255..71263,71348..71353,71399..71401))
                     /gene="araD"
                     /locus_tag="ECs_0065"
                     /note="active site"
                     /db_xref="CDD:238232"
     misc_feature    complement(order(70970..70972,71192..71194,71198..71200))
                     /gene="araD"
                     /locus_tag="ECs_0065"
                     /note="Zn2+ binding site [ion binding]; other site"
                     /db_xref="CDD:238232"
     gene            complement(71682..73184)
                     /gene="araA"
                     /locus_tag="ECs_0066"
                     /db_xref="GeneID:913468"
     CDS             complement(71682..73184)
                     /gene="araA"
                     /locus_tag="ECs_0066"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="NP_308093.1"
                     /db_xref="GeneID:913468"
                     /translation="MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVKALNTEAKL
                     PCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQ
                     FHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERI
                     GSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVV
                     NSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFT
                     TTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMED
                     YTYHFEKGNDLVLGSHMLEVCPSIAAEEKPILDVQHLGIGGKDDPARLIFNTQTGPAI
                     VASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHH
                     TVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR"
     misc_feature    complement(71685..73184)
                     /gene="araA"
                     /locus_tag="ECs_0066"
                     /note="L-arabinose isomerase; Provisional; Region:
                     PRK02929"
                     /db_xref="CDD:179503"
     misc_feature    complement(order(72342..72347,72372..72374,72537..72539,
                     72549..72569,72588..72590,72597..72599,72633..72635,
                     72654..72656,72762..72767,72921..72923,72981..72983,
                     72990..72992,73002..73004))
                     /gene="araA"
                     /locus_tag="ECs_0066"
                     /note="putative hexamer (dimer of trimers) interface
                     [polypeptide binding]; other site"
                     /db_xref="CDD:239619"
     misc_feature    complement(order(71712..71717,71784..71786,71838..71840,
                     71847..71849,71856..71858,71865..71870,71913..71915,
                     71919..71924,71928..71930,71985..71993,72168..72185,
                     72615..72626,72708..72710,72741..72743,72747..72749,
                     72762..72764,72768..72773,72780..72782,72789..72794,
                     72801..72806,72822..72824,72831..72839,72846..72848,
                     72852..72854,72858..72860,72867..72869,72873..72875,
                     72921..72932,72936..72938))
                     /gene="araA"
                     /locus_tag="ECs_0066"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:239619"
     misc_feature    complement(order(71835..71840,72186..72188,72267..72269,
                     72348..72350,72936..72938))
                     /gene="araA"
                     /locus_tag="ECs_0066"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:239619"
     misc_feature    complement(order(71835..71837,72186..72188,72267..72269))
                     /gene="araA"
                     /locus_tag="ECs_0066"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:239619"
     gene            complement(73195..74895)
                     /gene="araB"
                     /locus_tag="ECs_0067"
                     /db_xref="GeneID:913471"
     CDS             complement(73195..74895)
                     /gene="araB"
                     /locus_tag="ECs_0067"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulokinase"
                     /protein_id="NP_308094.1"
                     /db_xref="GeneID:913471"
                     /translation="MAIAIGLDFGSDSVRALAVDCTTGEEIATSVEWYPRWQKGQFCD
                     APNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDSTGSTPAPIDADGNVL
                     ALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKI
                     LHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLP
                     PASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCH
                     MGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAG
                     QSAFGDIYAWFGRVLGWPLEQLAAQHPELKEQIDASQKQLLPALTEAWAKNPSLDHLP
                     VVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGI
                     AVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIP
                     SAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVPTL
                     "
     misc_feature    complement(73237..74895)
                     /gene="araB"
                     /locus_tag="ECs_0067"
                     /note="ribulokinase; Provisional; Region: PRK04123"
                     /db_xref="CDD:235221"
     gene            75234..76112
                     /gene="araC"
                     /locus_tag="ECs_0068"
                     /db_xref="GeneID:913473"
     CDS             75234..76112
                     /gene="araC"
                     /locus_tag="ECs_0068"
                     /codon_start=1
                     /transl_table=11
                     /product="ara regulon transcriptional activator"
                     /protein_id="NP_308095.1"
                     /db_xref="GeneID:913473"
                     /translation="MAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKG
                     YILNLTIRGQGVVKNQGREFVCRPGDILLFPPGEIHHYGRHPEAREWYHQWVYFRPRA
                     YWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQGEGRYSELLAINLLEQLL
                     LRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQ
                     LGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEF
                     RAGCEEKVNDVAVKLS"
     misc_feature    75234..76088
                     /gene="araC"
                     /locus_tag="ECs_0068"
                     /note="arabinose operon transcriptional regulator AraC;
                     Region: PRK10572"
                     /db_xref="CDD:236717"
     gene            76198..76962
                     /gene="yabI"
                     /locus_tag="ECs_0069"
                     /db_xref="GeneID:913477"
     CDS             76198..76962
                     /gene="yabI"
                     /locus_tag="ECs_0069"
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family inner membrane protein"
                     /protein_id="NP_308096.1"
                     /db_xref="GeneID:913477"
                     /translation="MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAG
                     LGALIGSGELSFWHAWLAGIVGCLLGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTE
                     HALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPPFYFLPGI
                     LAGAAIDIPAGMQSGEFKWLLLATAVFLWVGGWLCWRLWRSGKATDRLSHYLSRGRLL
                     WLTPLISAIGVVALVVLVRHPLMPVYIDILRKVVGV"
     misc_feature    76219..76815
                     /gene="yabI"
                     /locus_tag="ECs_0069"
                     /note="Uncharacterized membrane protein DedA,
                     SNARE-associated domain [Function unknown]; Region: DedA;
                     COG0586"
                     /db_xref="CDD:223659"
     gene            complement(77049..77747)
                     /gene="thiQ"
                     /locus_tag="ECs_0070"
                     /db_xref="GeneID:913478"
     CDS             complement(77049..77747)
                     /gene="thiQ"
                     /locus_tag="ECs_0070"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine/thiamine pyrophosphate ABC transporter
                     ATPase"
                     /protein_id="NP_308097.1"
                     /db_xref="GeneID:913478"
                     /translation="MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNL
                     IAGFLTPASGALTIDGVDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKL
                     NAVQQEKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSAL
                     DPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGMTNELL
                     SGKASASALLGITG"
     misc_feature    complement(77055..77747)
                     /gene="thiQ"
                     /locus_tag="ECs_0070"
                     /note="thiamine ABC transporter ATP-binding protein ThiQ;
                     Region: thiQ; PRK10771"
                     /db_xref="CDD:182716"
     misc_feature    complement(77631..77654)
                     /gene="thiQ"
                     /locus_tag="ECs_0070"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213265"
     misc_feature    complement(order(77184..77186,77283..77288,77514..77516,
                     77628..77636,77640..77645))
                     /gene="thiQ"
                     /locus_tag="ECs_0070"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213265"
     misc_feature    complement(77514..77525)
                     /gene="thiQ"
                     /locus_tag="ECs_0070"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213265"
     misc_feature    complement(77331..77360)
                     /gene="thiQ"
                     /locus_tag="ECs_0070"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213265"
     misc_feature    complement(77283..77300)
                     /gene="thiQ"
                     /locus_tag="ECs_0070"
                     /note="Walker B; other site"
                     /db_xref="CDD:213265"
     misc_feature    complement(77265..77276)
                     /gene="thiQ"
                     /locus_tag="ECs_0070"
                     /note="D-loop; other site"
                     /db_xref="CDD:213265"
     misc_feature    complement(77178..77198)
                     /gene="thiQ"
                     /locus_tag="ECs_0070"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213265"
     gene            complement(77731..79341)
                     /gene="thiP"
                     /locus_tag="ECs_0071"
                     /db_xref="GeneID:913479"
     CDS             complement(77731..79341)
                     /gene="thiP"
                     /locus_tag="ECs_0071"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine transport system permease"
                     /protein_id="NP_308098.1"
                     /db_xref="GeneID:913479"
                     /translation="MATRRQPLIPGWLIPGVSAATLVVAVALAAFLALWWNAPQGDWS
                     AVWQDSYLWHVVRFSFWQAFLSALLSVVPAIFLARALYRRRFPGRLALLRLCAMTLIL
                     PVLVAVFGILSVYGRQGWLASLCQSLGLEWTFSPYGLQGILLAHVFFNLPMASRLLLQ
                     ALENIPGEQRQLAAQLGMRGWHFFRFVEWPWLRRQIPPVTALIFMLCFASFATVLSLG
                     GGPQATTIELAIYQALSYDYDPARAAMLALIQMVCCLGLVLLSQRLSKAIAPGTTLLQ
                     GWRDPDDRLHSRICDTMLIVLALLLLLPPLLAVIVDGVNRQLPEVLAQPVLWQALWTS
                     LRIALAAGVLCVVLTMMLLWSSRELRARQKMLAGQALEMSGMLILAMPGIVLATGFFL
                     LLNNTIGLPQSADGIVIFTNALMAIPYALKVLENPMRDITARYSMLCQSLGIEGWSRL
                     KVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDDFRTLPFYLYQQIGSYRSQDGA
                     VTALILLLLCFLLFSVIEKIPGRNVKTD"
     misc_feature    complement(77737..79311)
                     /gene="thiP"
                     /locus_tag="ECs_0071"
                     /note="thiamine transporter membrane protein; Reviewed;
                     Region: thiP; PRK09433"
                     /db_xref="CDD:181853"
     gene            complement(79317..80300)
                     /gene="thiB"
                     /locus_tag="ECs_0072"
                     /db_xref="GeneID:913490"
     CDS             complement(79317..80300)
                     /gene="thiB"
                     /locus_tag="ECs_0072"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine/thiamine pyrophosphate/thiamine
                     monophosphate ABC transporter periplasmic binding protein"
                     /protein_id="NP_308099.1"
                     /db_xref="GeneID:913490"
                     /translation="MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAF
                     EADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVA
                     ADAVNVPGGWNNDIFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRT
                     STPGLGLLLWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTS
                     PAYHILEEKKDNYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIP
                     TGNWMYPVANVTLPAGFEKLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR"
     misc_feature    complement(79320..80246)
                     /gene="thiB"
                     /locus_tag="ECs_0072"
                     /note="thiamine ABC transporter, periplasmic binding
                     protein; Region: thiB; TIGR01276"
                     /db_xref="CDD:130343"
     misc_feature    complement(order(79647..79652,79656..79658,79707..79715,
                     79812..79817))
                     /gene="thiB"
                     /locus_tag="ECs_0072"
                     /note="chemical substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:270263"
     gene            80672..81241
                     /gene="espY2"
                     /locus_tag="ECs_0073"
                     /db_xref="GeneID:913497"
     CDS             80672..81241
                     /gene="espY2"
                     /locus_tag="ECs_0073"
                     /codon_start=1
                     /transl_table=11
                     /product="T3SS effector-like protein EspY"
                     /protein_id="NP_308100.1"
                     /db_xref="GeneID:913497"
                     /translation="MKVRNPEQISIPASNTTKDPGLTNSQIIRMANLVKKTENMNIFE
                     ELWETLRNLFQSDKHSQTAARQILKDAFYFQNSDDYSKYFTGAVDGKARDKLTHWLIK
                     FNELKEYAKDPENMAAKASLSPEGTLCVSFFIGDEAIFTLELQLKKSTRTGGIDLSNA
                     YFNGVVICGIDCLEVDLSNAETNNSRWYD"
     gene            complement(81470..83128)
                     /gene="sgrR"
                     /locus_tag="ECs_0074"
                     /db_xref="GeneID:913502"
     CDS             complement(81470..83128)
                     /gene="sgrR"
                     /locus_tag="ECs_0074"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator"
                     /protein_id="NP_308101.1"
                     /db_xref="GeneID:913502"
                     /translation="MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLL
                     NTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKAT
                     VRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEE
                     NGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIA
                     DIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRN
                     STNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEG
                     CYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHART
                     ITSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIES
                     DIWLNSANFTLPLDFSLFAHLCEVPLLQHCIPIDWQVDAARWRNGEMNLANWCQQLVA
                     SKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDPE"
     misc_feature    complement(81476..83128)
                     /gene="sgrR"
                     /locus_tag="ECs_0074"
                     /note="HTH-type transcriptional regulator SgrR; Region:
                     PRK13626"
                     /db_xref="CDD:184188"
     gene            complement(83456..84061)
                     /gene="leuD"
                     /locus_tag="ECs_0075"
                     /db_xref="GeneID:913503"
     CDS             complement(83456..84061)
                     /gene="leuD"
                     /locus_tag="ECs_0075"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="NP_308102.1"
                     /db_xref="GeneID:913503"
                     /translation="MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLF
                     NDWRFLDEKGQQPNPDFVLNFSQYQGASILLARENFGCGSSREHAPWALTDYGFKVVI
                     APSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTY
                     RFTIDAFRRHCMMNGLDSIGLTLQHDDAIAAYEAKQPAFMR"
     misc_feature    complement(83459..84055)
                     /gene="leuD"
                     /locus_tag="ECs_0075"
                     /note="3-isopropylmalate dehydratase small subunit;
                     Region: leuD; PRK01641"
                     /db_xref="CDD:179314"
     misc_feature    complement(83804..83812)
                     /gene="leuD"
                     /locus_tag="ECs_0075"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238809"
     gene            complement(84072..85472)
                     /gene="leuC"
                     /locus_tag="ECs_0076"
                     /db_xref="GeneID:913504"
     CDS             complement(84072..85472)
                     /gene="leuC"
                     /locus_tag="ECs_0076"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="NP_308103.1"
                     /db_xref="GeneID:913504"
                     /translation="MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGL
                     RAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNH
                     PYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ
                     GRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMT
                     LCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTV
                     VTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGILL
                     TEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLD
                     KIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMA
                     AAAAVTGHFADIRNIK"
     misc_feature    complement(84075..85472)
                     /gene="leuC"
                     /locus_tag="ECs_0076"
                     /note="3-isopropylmalate dehydratase large subunit;
                     Region: PRK05478"
                     /db_xref="CDD:235490"
     misc_feature    complement(order(84168..84170,84183..84185,84240..84242,
                     85086..85091,85365..85367,85374..85376))
                     /gene="leuC"
                     /locus_tag="ECs_0076"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:153133"
     misc_feature    complement(order(84186..84188,84240..84245,84252..84254,
                     84432..84434,85083..85085))
                     /gene="leuC"
                     /locus_tag="ECs_0076"
                     /note="ligand binding site [chemical binding]; other site"
                     /db_xref="CDD:153133"
     gene            complement(85475..86566)
                     /gene="leuB"
                     /locus_tag="ECs_0077"
                     /db_xref="GeneID:913510"
     CDS             complement(85475..86566)
                     /gene="leuB"
                     /locus_tag="ECs_0077"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="NP_308104.2"
                     /db_xref="GeneID:913510"
                     /translation="MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYD
                     VGGAAIDNHGQPLPPATVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHF
                     KLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEK
                     AFDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPD
                     IELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQG
                     FGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADDAASAIERAINRALEEGI
                     RTGDLARGAAAVSTDEMGDIIARYVAEGV"
     misc_feature    complement(85481..86560)
                     /gene="leuB"
                     /locus_tag="ECs_0077"
                     /note="3-isopropylmalate dehydrogenase; Provisional;
                     Region: PRK00772"
                     /db_xref="CDD:234832"
     gene            complement(86566..88137)
                     /gene="leuA"
                     /locus_tag="ECs_0078"
                     /db_xref="GeneID:913513"
     CDS             complement(86566..88137)
                     /gene="leuA"
                     /locus_tag="ECs_0078"
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="NP_308105.1"
                     /db_xref="GeneID:913513"
                     /translation="MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVME
                     VGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIAT
                     SPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAIN
                     AGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAV
                     HAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQI
                     CNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGR
                     AAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIGKQQEEPEHFR
                     LDYFSVQSGSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITDYNVELVKYS
                     LTAKGHGKDALGQVDIVANYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRATEVEKE
                     LQRKAQHNENNKETV"
     misc_feature    complement(86602..88137)
                     /gene="leuA"
                     /locus_tag="ECs_0078"
                     /note="2-isopropylmalate synthase; Validated; Region:
                     PRK00915"
                     /db_xref="CDD:234864"
     misc_feature    complement(order(87526..87528,87532..87534,87625..87627,
                     87631..87633,87715..87717,87721..87723,87847..87849,
                     87913..87915,88006..88008,88087..88089,88096..88101))
                     /gene="leuA"
                     /locus_tag="ECs_0078"
                     /note="active site"
                     /db_xref="CDD:163678"
     misc_feature    complement(order(88006..88008,88096..88101))
                     /gene="leuA"
                     /locus_tag="ECs_0078"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:163678"
     misc_feature    complement(order(87526..87528,87532..87534))
                     /gene="leuA"
                     /locus_tag="ECs_0078"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:163678"
     gene            complement(88230..88316)
                     /gene="leuL"
                     /locus_tag="ECs_0079"
                     /db_xref="GeneID:913517"
     CDS             complement(88230..88316)
                     /gene="leuL"
                     /locus_tag="ECs_0079"
                     /codon_start=1
                     /transl_table=11
                     /product="leu operon leader peptide"
                     /protein_id="NP_308106.1"
                     /db_xref="GeneID:913517"
                     /translation="MTHIVRFIGLLLLNASSLRGRRVSGIQH"
     misc_feature    complement(88233..88316)
                     /gene="leuL"
                     /locus_tag="ECs_0079"
                     /note="leu operon leader peptide; Provisional; Region:
                     PRK09925"
                     /db_xref="CDD:137592"
     gene            88974..89918
                     /gene="leuO"
                     /locus_tag="ECs_0080"
                     /db_xref="GeneID:913520"
     CDS             88974..89918
                     /gene="leuO"
                     /locus_tag="ECs_0080"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator LeuO"
                     /protein_id="NP_308107.3"
                     /db_xref="GeneID:913520"
                     /translation="MPEVQTDHPETAEFSKPQLRMVDLNLLTVFDAVMQEQNITRAAH
                     VLGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTARAFQLFGSVRQALQLVQNELPG
                     SGFEPASSERVFHLCVCSPLDSILTSQIYNHIEQIAPNIHVMFKSSLNQNTEHQLRYQ
                     ETEFVISYEDFHRPEFTSVPLFKDEMVLVASKNHPTIKGPLLKHDVYNEQHAAVSLDR
                     FASFSQPWYDTVDKQASIAYQGMAMMSVLSVVSQTHLVAIAPRWLAEEFAESLELQVL
                     PLPLKLNSRTCYLSWHEAAGRDKGHQWMEEQLVSICKR"
     misc_feature    88974..89915
                     /gene="leuO"
                     /locus_tag="ECs_0080"
                     /note="leucine transcriptional activator; Reviewed;
                     Region: leuO; PRK09508"
                     /db_xref="CDD:181918"
     gene            90236..91960
                     /gene="ilvI"
                     /locus_tag="ECs_0081"
                     /db_xref="GeneID:913521"
     CDS             90236..91960
                     /gene="ilvI"
                     /locus_tag="ECs_0081"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 3 large subunit"
                     /protein_id="NP_308108.2"
                     /db_xref="GeneID:913521"
                     /translation="MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGIG
                     HVLVRHEQAAVHMADGLARATGEVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQ
                     VATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVD
                     LPKDILNPANKLPYVWPESVSMRSYNPTTTGHKGQIKRALQTLVAAKKPVVYVGGGAI
                     TAGCHQQLKETVEALNLPVVSSLMGLGAFPATHRQALGMLGMHGTYEANMTMHNADVI
                     FAVGVRFDDRTTNNLAKYCPNATVLHIDIDPTSISKTVTADIPIVGDARQVLEQMLEL
                     LSQESAHQPLDEIRDWWQQIEQWRARQCLKYDTHSEKIKPQAVIETLWRLTKGGAYVT
                     SDVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGS
                     IQMNIQELSTALQYELPVLVVNLNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLA
                     EAYGHVGIQISHPQELESKLSEALEQVRNNRLVFVDVTVDGSEHVYPMQIRGGGMDEM
                     WLSKTERT"
     misc_feature    90236..91957
                     /gene="ilvI"
                     /locus_tag="ECs_0081"
                     /note="acetolactate synthase 3 large subunit; Region:
                     PRK07979"
                     /db_xref="CDD:181185"
     gene            91963..92454
                     /gene="ilvH"
                     /locus_tag="ECs_0082"
                     /db_xref="GeneID:913523"
     CDS             91963..92454
                     /gene="ilvH"
                     /locus_tag="ECs_0082"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 3 small subunit"
                     /protein_id="NP_308109.1"
                     /db_xref="GeneID:913523"
                     /translation="MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLS
                     RMTIQTVGDEKVLEQIEKQLYKLVDVLRVSELGQGAHVEREIMLVKIQASGYGRDEVK
                     RNTEIFRGQIIDVTPSLYTVQLAGTSDKLDAFLASIRDVAKIVEVARSGVVGLSRGDK
                     IMR"
     misc_feature    91963..92448
                     /gene="ilvH"
                     /locus_tag="ECs_0082"
                     /note="acetolactate synthase 3 regulatory subunit;
                     Reviewed; Region: ilvH; PRK11895"
                     /db_xref="CDD:183365"
     gene            92466..92552
                     /gene="fruR"
                     /locus_tag="ECs_0083"
                     /db_xref="GeneID:913524"
     CDS             92466..92552
                     /gene="fruR"
                     /locus_tag="ECs_0083"
                     /codon_start=1
                     /transl_table=11
                     /product="fruR leader peptide"
                     /protein_id="NP_308110.1"
                     /db_xref="GeneID:913524"
                     /translation="MRNLQPNMSRWAFFAKSVGTWNKSSCRS"
     gene            92634..93638
                     /gene="fruR"
                     /locus_tag="ECs_0084"
                     /db_xref="GeneID:913527"
     CDS             92634..93638
                     /gene="fruR"
                     /locus_tag="ECs_0084"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional dual regulator FruR"
                     /protein_id="NP_308111.1"
                     /db_xref="GeneID:913527"
                     /translation="MKLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVRE
                     HNYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQ
                     PDNEMRCIEHLLQRQVDAIIVSTSLPPEHPFYQRWANDPFPIVALDRALDREHFTSVV
                     GADQDDAEMLAEELRKFPAETVLYLGALPELSVSFLREQGFRTAWKDDPREVHFLYAN
                     SYEREAAAQLFEKWLETHPMPQALFTTSFALLQGVMDVTLRRDGKLPSDLAIATFGDN
                     ELLDFLQCPVLAVAQRHRDVAERVLEIVLASLDEPRKPKPGLTRIKRNLYRRGVLSRS
                     "
     misc_feature    92634..93617
                     /gene="fruR"
                     /locus_tag="ECs_0084"
                     /note="catabolite repressor/activator; Region: PRK11303"
                     /db_xref="CDD:236897"
     gene            94240..94698
                     /gene="mraZ"
                     /locus_tag="ECs_0085"
                     /db_xref="GeneID:913528"
     CDS             94240..94698
                     /gene="mraZ"
                     /locus_tag="ECs_0085"
                     /codon_start=1
                     /transl_table=11
                     /product="RsmH methyltransferase inhibitor"
                     /protein_id="NP_308112.1"
                     /db_xref="GeneID:913528"
                     /translation="MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIHHPC
                     LLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHA
                     GLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL"
     misc_feature    94240..94692
                     /gene="mraZ"
                     /locus_tag="ECs_0085"
                     /note="division/cell wall cluster transcriptional
                     repressor MraZ; Region: TIGR00242"
                     /db_xref="CDD:129345"
     gene            94700..95641
                     /gene="rsmH"
                     /locus_tag="ECs_0086"
                     /db_xref="GeneID:913531"
     CDS             94700..95641
                     /gene="rsmH"
                     /locus_tag="ECs_0086"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA m(4)C1402 methyltransferase"
                     /protein_id="NP_308113.1"
                     /db_xref="GeneID:913531"
                     /translation="MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQ
                     LGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDL
                     GVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERF
                     AKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEE
                     IEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKL
                     GGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA"
     misc_feature    94700..95638
                     /gene="rsmH"
                     /locus_tag="ECs_0086"
                     /note="16S rRNA C1402 N4-methylase RsmH [Translation,
                     ribosomal structure and biogenesis]; Region: RmsH;
                     COG0275"
                     /db_xref="CDD:223352"
     gene            95638..96003
                     /gene="ftsL"
                     /locus_tag="ECs_0087"
                     /db_xref="GeneID:913534"
     CDS             95638..96003
                     /gene="ftsL"
                     /locus_tag="ECs_0087"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane bound cell division leucine zipper
                     septum protein"
                     /protein_id="NP_308114.1"
                     /db_xref="GeneID:913534"
                     /translation="MISRVTEALSKVKGSMGSHERHALPGVIGDDLLRFGKLPLCLFI
                     CIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIAT
                     EKLQMQHVDPSQENIVVQK"
     misc_feature    95686..96000
                     /gene="ftsL"
                     /locus_tag="ECs_0087"
                     /note="cell division protein FtsL; Provisional; Region:
                     PRK10772"
                     /db_xref="CDD:182717"
     gene            96019..97785
                     /gene="ftsI"
                     /locus_tag="ECs_0088"
                     /db_xref="GeneID:913535"
     CDS             96019..97785
                     /gene="ftsI"
                     /locus_tag="ECs_0088"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsI"
                     /protein_id="NP_308115.1"
                     /db_xref="GeneID:913535"
                     /translation="MKAAAKTQKPKRQEEHANFISWRFALLCGCILLALAFLLGRVAW
                     LQVISPDMLVKEGDMRSLRVQQVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHDAG
                     GISVGDRWKALANALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIH
                     LREESRRYYPSGEVTAHLIGFTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVI
                     EDISSTDSQAAHNLALSIDERLQALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMA
                     NSPSYNPNNLSGTPKEAMRNRTITDVFEPGSTVKPMVVMTALQRGVVRENSVLNTIPY
                     RINGHEIKDVARYSELTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKATNLG
                     LVGERSGLYPQKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSYGIYRPLSITKVD
                     PPVPGERVFPESIVRTVVHMMESVALPGGGGVKAAIKGYRIAIKTGTAKKVGPDGRYI
                     NKYIAYTAGVAPASQPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRTMNIEPD
                     ALTTGDKNEFVINQGEGTGGRS"
     misc_feature    96022..97755
                     /gene="ftsI"
                     /locus_tag="ECs_0088"
                     /note="peptidoglycan synthase FtsI; Provisional; Region:
                     PRK15105"
                     /db_xref="CDD:185060"
     gene            97772..99259
                     /gene="murE"
                     /locus_tag="ECs_0089"
                     /db_xref="GeneID:913536"
     CDS             97772..99259
                     /gene="murE"
                     /locus_tag="ECs_0089"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-
                     diaminopimelate ligase"
                     /protein_id="NP_308116.1"
                     /db_xref="GeneID:913536"
                     /translation="MADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGH
                     QADGRRYIPQAIAQGVAAIIAEAKGEATDGEIREMHGVPVIYLSQLNERLSALAGRFY
                     HEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGETSAVMGTVGNGLLGKVIPTENTTG
                     SAVDVQHELAGLVDQDATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDM
                     EHYEAAKWLLYSEHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKA
                     TEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAA
                     RLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDK
                     GKRPLMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGMLDAGHAKVMEDRAEAVTC
                     AVMQAKENDVVLVAGKGHEDYQIVGNQRLDYSDRVTVARLLGVIA"
     misc_feature    97772..99253
                     /gene="murE"
                     /locus_tag="ECs_0089"
                     /note="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase; Provisional; Region: murE;
                     PRK00139"
                     /db_xref="CDD:234660"
     gene            99256..100614
                     /gene="murF"
                     /locus_tag="ECs_0090"
                     /db_xref="GeneID:913537"
     CDS             99256..100614
                     /gene="murF"
                     /locus_tag="ECs_0090"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-
                     alanine ligase"
                     /protein_id="NP_308117.1"
                     /db_xref="GeneID:913537"
                     /translation="MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALK
                     GERFDAHDFADQAKAGGAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARV
                     VALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELG
                     ANHQGEIVWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMN
                     ADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLP
                     LPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYN
                     ANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHVQVGEAAKAAGIDRVLSVGK
                     QSHAISTASGVGEHFAEKTALITRLKSLIAEQQVITILVKGSRSAAMEEVVRALQENG
                     TC"
     misc_feature    99256..100611
                     /gene="murF"
                     /locus_tag="ECs_0090"
                     /note="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine
                     ligase; Reviewed; Region: murF; PRK10773"
                     /db_xref="CDD:182718"
     gene            100608..101690
                     /gene="mraY"
                     /locus_tag="ECs_0091"
                     /db_xref="GeneID:913542"
     CDS             100608..101690
                     /gene="mraY"
                     /locus_tag="ECs_0091"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="NP_308118.1"
                     /db_xref="GeneID:913542"
                     /translation="MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRM
                     IAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVL
                     VVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLVGKDTPATQL
                     VVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWA
                     TGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGA
                     LGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWP
                     EPRVIVRFWIISLMLVLIGLATLKVR"
     misc_feature    100716..101687
                     /gene="mraY"
                     /locus_tag="ECs_0091"
                     /note="phospho-N-acetylmuramoyl-pentapeptide-transferase;
                     Region: mraY; TIGR00445"
                     /db_xref="CDD:161884"
     misc_feature    100950..100955
                     /gene="mraY"
                     /locus_tag="ECs_0091"
                     /note="Mg++ binding site [ion binding]; other site"
                     /db_xref="CDD:133462"
     misc_feature    101397..101408
                     /gene="mraY"
                     /locus_tag="ECs_0091"
                     /note="putative catalytic motif [active]"
                     /db_xref="CDD:133462"
     misc_feature    order(101556..101558,101574..101588)
                     /gene="mraY"
                     /locus_tag="ECs_0091"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:133462"
     gene            101693..103009
                     /gene="murD"
                     /locus_tag="ECs_0092"
                     /db_xref="GeneID:913546"
     CDS             101693..103009
                     /gene="murD"
                     /locus_tag="ECs_0092"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine:D-glutamate
                     ligase"
                     /protein_id="NP_308119.1"
                     /db_xref="GeneID:913546"
                     /translation="MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGL
                     DKLPEAVERHTGSLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCRE
                     AQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDDECELYVLELS
                     SFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALT
                     MPIRGADERCVSFGVNMGDYHLNHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAA
                     LALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWINDSKATNVGSTEAALNGL
                     HVDGTLHLLLGGDGKSADFSPLARYLNGDNVRLYCFGRDGVQLAALRPEVAEQTETME
                     QAMRLLAPRVQPGDMVLLSPACASLDQFKNFEQRGNEFARLAKELG"
     misc_feature    101693..103006
                     /gene="murD"
                     /locus_tag="ECs_0092"
                     /note="UDP-N-acetylmuramoylalanine-D-glutamate ligase
                     [Cell wall/membrane/envelope biogenesis]; Region: MurD;
                     COG0771"
                     /db_xref="CDD:223842"
     gene            103009..104253
                     /gene="ftsW"
                     /locus_tag="ECs_0093"
                     /db_xref="GeneID:913549"
     CDS             103009..104253
                     /gene="ftsW"
                     /locus_tag="ECs_0093"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II flippase FtsW"
                     /protein_id="NP_308120.1"
                     /db_xref="GeneID:913549"
                     /translation="MRLSLPRLKMPRLPGFSILVWISTALKGWVMGSREKDTDSLIMY
                     DRTLLWLTFGLAAIGFIMVTSASMPIGQRLTNDPFFFAKRDGVYLILAFILAIITLRL
                     PMEFWQRYSATMLLGSIILLMIVLVVGSSVKGASRWIDLGLLRIQPAELTKLSLFCYI
                     ANYLVRKGDEVRNNLRGFLKPMGVILVLAVLLLAQPDLGTVVVLFVTTLAMLFLAGAK
                     LWQFIAIIGMGISAVVLLILAEPYRIRRVTAFWNPWEDPFGSGYQLTQSLMAFGRGEL
                     WGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYVGVVLALLMVFFVAFRAMSIGRKAL
                     EIDHRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIM
                     MLLRIDYETRLEKAQAFVRGSR"
     misc_feature    103039..104250
                     /gene="ftsW"
                     /locus_tag="ECs_0093"
                     /note="cell division protein FtsW; Provisional; Region:
                     PRK10774"
                     /db_xref="CDD:182719"
     gene            104250..105317
                     /gene="murG"
                     /locus_tag="ECs_0094"
                     /db_xref="GeneID:913552"
     CDS             104250..105317
                     /gene="murG"
                     /locus_tag="ECs_0094"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminyl transferase"
                     /protein_id="NP_308121.1"
                     /db_xref="GeneID:913552"
                     /translation="MSAQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADR
                     MEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGM
                     GGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGN
                     PVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQS
                     GKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPA
                     LFVPFQHKDRQQYWNALPLEKAGAAKIIEQPQLSVDAVANTLAGWSRETLLTMAERAR
                     AASIPDATERVANEVSRAARA"
     misc_feature    104265..105314
                     /gene="murG"
                     /locus_tag="ECs_0094"
                     /note="undecaprenyldiphospho-muramoylpentapeptide beta-N-
                     acetylglucosaminyltransferase; Provisional; Region: murG;
                     PRK00726"
                     /db_xref="CDD:234825"
     gene            105371..106846
                     /gene="murC"
                     /locus_tag="ECs_0095"
                     /db_xref="GeneID:913555"
     CDS             105371..106846
                     /gene="murC"
                     /locus_tag="ECs_0095"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate:L-alanine ligase"
                     /protein_id="NP_308122.1"
                     /db_xref="GeneID:913555"
                     /translation="MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGY
                     QISGSDLAPNPVTQQLMNLGATIYFNHRPENVRDASVVVVSSAISADNPEIVAAHEAR
                     IPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAG
                     VHARLGHGRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFL
                     HNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLR
                     QDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALESFQGTGRRFDFLGEF
                     PLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRFTRTRDLYD
                     DFANVLTQVDTLLMLEVYPAGEAPIPGADSRSLCRTIRGRGKIDPILVPDPAQVAEML
                     APVLTGNDLILVQGAGNIGKIARSLAEIKLKPQTPEEEQHD"
     misc_feature    105431..106798
                     /gene="murC"
                     /locus_tag="ECs_0095"
                     /note="UDP-N-acetylmuramate--L-alanine ligase; Region:
                     murC; TIGR01082"
                     /db_xref="CDD:273433"
     gene            106839..107759
                     /gene="ddlB"
                     /locus_tag="ECs_0096"
                     /db_xref="GeneID:913558"
     CDS             106839..107759
                     /gene="ddlB"
                     /locus_tag="ECs_0096"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine:D-alanine ligase"
                     /protein_id="NP_308123.1"
                     /db_xref="GeneID:913558"
                     /translation="MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKE
                     VDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKL
                     LWQGAGLPVAPWVALTRVEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAE
                     NALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSVRIQPSGTFYDYEAKYLS
                     DETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPG
                     MTSHSLVPMAARQAGMSFSQLVVRILELAD"
     misc_feature    106839..107756
                     /gene="ddlB"
                     /locus_tag="ECs_0096"
                     /note="D-alanine--D-alanine ligase; Reviewed; Region: ddl;
                     PRK01372"
                     /db_xref="CDD:234948"
     gene            107761..108591
                     /gene="ftsQ"
                     /locus_tag="ECs_0097"
                     /db_xref="GeneID:913560"
     CDS             107761..108591
                     /gene="ftsQ"
                     /locus_tag="ECs_0097"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ"
                     /protein_id="NP_308124.1"
                     /db_xref="GeneID:913560"
                     /translation="MSQAALNTRNSEEEVSSRRNNGTRLAGILFLLTVLTTVLVSGWV
                     VLGWMEDAQRLPLSKLVLTGERHYTRNDDIRQSILALGEPGTFMTQDVNIIQTQIEQR
                     LPWIKQVSVRKQWPDELKIHLVEYVPIARWNDQHMVDAEGNTFSVPPDRTSKQVLPML
                     YGPEGSANEVLQGYREMGQMLAKDRFTLKEAAMTARRSWQLTLNNDIKLNLGRGDTMK
                     RLARFVELYPVLQQQAQTDGKRISYVDLRYDSGAAVGWAPLPPEESTQQQNQAQAEQQ
                     "
     misc_feature    107761..108552
                     /gene="ftsQ"
                     /locus_tag="ECs_0097"
                     /note="cell division protein FtsQ; Provisional; Region:
                     PRK10775"
                     /db_xref="CDD:182720"
     gene            108588..109850
                     /gene="ftsA"
                     /locus_tag="ECs_0098"
                     /db_xref="GeneID:913567"
     CDS             108588..109850
                     /gene="ftsA"
                     /locus_tag="ECs_0098"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="NP_308125.1"
                     /db_xref="GeneID:913567"
                     /translation="MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSR
                     GMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEE
                     EVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
                     ITCHNDMAKNIVKAVERCGLKVDQLIFAGLASSYSVLTEDERELGVCVVDIGGGTMDI
                     AVYTGGALRHTKVIPYAGNVVTSDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVE
                     VPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEKLRQQGVKHHLAAGIVL
                     TGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLN
                     GEAEVEKRVTASVGSWIKRLNSWLRKEF"
     misc_feature    108588..109847
                     /gene="ftsA"
                     /locus_tag="ECs_0098"
                     /note="cell division protein FtsA; Reviewed; Region: ftsA;
                     PRK09472"
                     /db_xref="CDD:181887"
     gene            109911..111062
                     /gene="ftsZ"
                     /locus_tag="ECs_0099"
                     /db_xref="GeneID:913575"
     CDS             109911..111062
                     /gene="ftsZ"
                     /locus_tag="ECs_0099"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding tubulin-like cell division protein
                     FtsZ"
                     /protein_id="NP_308126.1"
                     /db_xref="GeneID:913575"
                     /translation="MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNT
                     DAQALRKTAVGQTIQIGSGITKGLGAGANPEVGRNAADEDRDALRAALEGADMVFIAA
                     GMGGGTGTGAAPVVAEVAKDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSL
                     ITIPNDKLLKVLGRGISLLDAFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMS
                     EMGYAMMGSGVASGEDRAEEAAEMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFE
                     TVGNTIRAFASDNATVVIGTSLDPDMNDELRVTVVATGIGMDKRPEITLVTNKQVQQP
                     VMDRYQQHGMAPLTQEQKPVAKVVNDNAPQTAKEPDYLDIPAFLRKQAD"
     misc_feature    109980..110852
                     /gene="ftsZ"
                     /locus_tag="ECs_0099"
                     /note="Filamenting temperature sensitive mutant Z, type 1;
                     Region: FtsZ_type1; cd02201"
                     /db_xref="CDD:276961"
     misc_feature    order(109980..109982,110217..110222,110226..110237,
                     110310..110312,110322..110324,110334..110336,
                     110403..110405,110454..110456,110463..110468,
                     110475..110477)
                     /gene="ftsZ"
                     /locus_tag="ECs_0099"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:276961"
     misc_feature    order(110526..110531,110535..110537,110718..110726,
                     110733..110735)
                     /gene="ftsZ"
                     /locus_tag="ECs_0099"
                     /note="SulA interaction site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:276961"
     misc_feature    <110928..111059
                     /gene="ftsZ"
                     /locus_tag="ECs_0099"
                     /note="cell division protein FtsZ, alphaProteobacterial
                     C-terminal extension; Region: FtsZ_alphas_C; TIGR03483"
                     /db_xref="CDD:274601"
     gene            111163..112080
                     /gene="lpxC"
                     /locus_tag="ECs_0100"
                     /db_xref="GeneID:913579"
     CDS             111163..112080
                     /gene="lpxC"
                     /locus_tag="ECs_0100"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-acyl N-acetylglucosamine deacetylase"
                     /protein_id="NP_308127.1"
                     /db_xref="GeneID:913579"
                     /translation="MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDL
                     NPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIP
                     IMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTID
                     FNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVV
                     DDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVL
                     AKQEAWEYVTFQDDAELPLAFKAPSAVLA"
     misc_feature    111166..112065
                     /gene="lpxC"
                     /locus_tag="ECs_0100"
                     /note="UDP-3-0-acyl N-acetylglucosamine deacetylase;
                     Region: lpxC; TIGR00325"
                     /db_xref="CDD:273014"
     gene            112311..112823
                     /gene="secM"
                     /locus_tag="ECs_0101"
                     /db_xref="GeneID:913588"
     CDS             112311..112823
                     /gene="secM"
                     /locus_tag="ECs_0101"
                     /codon_start=1
                     /transl_table=11
                     /product="SecA regulator SecM"
                     /protein_id="NP_308128.2"
                     /db_xref="GeneID:913588"
                     /translation="MSGILTRWRQFGKRYFWPHLLLGMVAASLGLPALSNAAEPNAPA
                     KATTRNHEPSAKVNFGQLALLEANTRRPNSNYSVDYWHQHAIRTVIRHLSFAMAPQTL
                     PVAEESLPLQAQHLALLDTLSALLTQEGTPSEKGYRIDYAHFTPQAKFSTPVWISQAQ
                     GIRAGPQRLS"
     misc_feature    112314..112820
                     /gene="secM"
                     /locus_tag="ECs_0101"
                     /note="secA regulator SecM; Region: PRK02943"
                     /db_xref="CDD:235088"
     gene            112885..115590
                     /gene="secA"
                     /locus_tag="ECs_0102"
                     /db_xref="GeneID:913599"
     CDS             112885..115590
                     /gene="secA"
                     /locus_tag="ECs_0102"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit"
                     /protein_id="NP_308129.1"
                     /db_xref="GeneID:913599"
                     /translation="MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELK
                     GKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEM
                     RTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPG
                     MPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDE
                     ARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTE
                     RGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVI
                     IVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTG
                     TADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQ
                     PVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAG
                     RGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLAAGGLHIIGTERHESRR
                     IDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVT
                     KAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIRED
                     VFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERIL
                     AQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKD
                     PKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQ
                     LSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ"
     misc_feature    112888..115587
                     /gene="secA"
                     /locus_tag="ECs_0102"
                     /note="preprotein translocase subunit SecA; Reviewed;
                     Region: PRK12904"
                     /db_xref="CDD:237259"
     gene            115650..116048
                     /gene="mutT"
                     /locus_tag="ECs_0103"
                     /db_xref="GeneID:913600"
     CDS             115650..116048
                     /gene="mutT"
                     /locus_tag="ECs_0103"
                     /codon_start=1
                     /transl_table=11
                     /product="dGTP-preferring nucleoside triphosphate
                     pyrophosphohydrolase"
                     /protein_id="NP_308130.1"
                     /db_xref="GeneID:913600"
                     /translation="MKKLQIAVGIIRNENNEIFITRRAADAHMANKLEFPGGKIEMGE
                     TPEQAVVRELQEEVGITPQHFSLFEKLEYEFPDRHITLWFWLVESWEGEPWGKEGQPG
                     KWMSLVGLNADDFPPANEPVIAKLKRVYVG"
     misc_feature    115650..116033
                     /gene="mutT"
                     /locus_tag="ECs_0103"
                     /note="8-oxo-dGTP diphosphatase MutT; Region: PRK10776"
                     /db_xref="CDD:182721"
     misc_feature    order(115659..115661,115665..115667,115761..115766,
                     115770..115772,115806..115808,115815..115820,
                     115887..115889,115941..115943,116004..116006)
                     /gene="mutT"
                     /locus_tag="ECs_0103"
                     /note="active site"
                     /db_xref="CDD:239517"
     misc_feature    order(115659..115661,115665..115667,115761..115766,
                     115881..115883,115887..115889,116004..116006)
                     /gene="mutT"
                     /locus_tag="ECs_0103"
                     /note="8-oxo-dGMP binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239517"
     misc_feature    115761..115829
                     /gene="mutT"
                     /locus_tag="ECs_0103"
                     /note="nudix motif; other site"
                     /db_xref="CDD:239517"
     misc_feature    order(115806..115808,115815..115820)
                     /gene="mutT"
                     /locus_tag="ECs_0103"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:239517"
     gene            complement(116139..116336)
                     /gene="yacG"
                     /locus_tag="ECs_0105"
                     /db_xref="GeneID:913611"
     CDS             complement(116139..116336)
                     /gene="yacG"
                     /locus_tag="ECs_0105"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor"
                     /protein_id="NP_308132.1"
                     /db_xref="GeneID:913611"
                     /translation="MSETITVNCPTCGKTVVWGEISPFRPFCSKRCQLIDLGEWAAEE
                     KRIPSSGDLSESDDWSEEPKQ"
     misc_feature    complement(116151..116336)
                     /gene="yacG"
                     /locus_tag="ECs_0105"
                     /note="DNA gyrase inhibitor YacG; Region: PRK00418"
                     /db_xref="CDD:234754"
     gene            complement(116346..117089)
                     /gene="zapD"
                     /locus_tag="ECs_0106"
                     /db_xref="GeneID:913614"
     CDS             complement(116346..117089)
                     /gene="zapD"
                     /locus_tag="ECs_0106"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapD"
                     /protein_id="NP_308133.1"
                     /db_xref="GeneID:913614"
                     /translation="MQTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFF
                     RNVSELLDVFERGEVRTELLKELDRQQRKLQTWIGVPGVDQSRIEALIQQLKAAGSVL
                     ISAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLPQAQRDCQVETWIAS
                     LNPLTQALTMVLDLIRQSAPFRKQTSLNGFYQDNGGDADLLRLNLSLDSQLYPQISGH
                     KSRFAIRFMPLDTENGQVPERLDFELACC"
     misc_feature    complement(116349..117080)
                     /gene="zapD"
                     /locus_tag="ECs_0106"
                     /note="Cell division protein ZapD, interacts with FtsZ
                     [Cell cycle control, cell division, chromosome
                     partitioning]; Region: ZapD; COG4582"
                     /db_xref="CDD:226948"
     gene            complement(117089..117709)
                     /gene="coaE"
                     /locus_tag="ECs_0107"
                     /db_xref="GeneID:913615"
     CDS             complement(117089..117709)
                     /gene="coaE"
                     /locus_tag="ECs_0107"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="NP_308134.1"
                     /db_xref="GeneID:913615"
                     /translation="MRYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGA
                     PALHAIADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQ
                     ATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQA
                     TREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQFVSQEKP"
     misc_feature    complement(117179..117703)
                     /gene="coaE"
                     /locus_tag="ECs_0107"
                     /note="Dephospho-CoA kinase; Region: CoaE; pfam01121"
                     /db_xref="CDD:426062"
     misc_feature    complement(order(117233..117235,117368..117373,
                     117443..117445,117611..117613,117686..117688))
                     /gene="coaE"
                     /locus_tag="ECs_0107"
                     /note="CoA-binding site [chemical binding]; other site"
                     /db_xref="CDD:238980"
     misc_feature    complement(order(117185..117187,117290..117292,
                     117665..117670,117677..117685))
                     /gene="coaE"
                     /locus_tag="ECs_0107"
                     /note="ATP-binding [chemical binding]; other site"
                     /db_xref="CDD:238980"
     gene            117934..118977
                     /gene="guaC"
                     /locus_tag="ECs_0108"
                     /db_xref="GeneID:913617"
     CDS             117934..118977
                     /gene="guaC"
                     /locus_tag="ECs_0108"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="NP_308135.1"
                     /db_xref="GeneID:913617"
                     /translation="MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQSW
                     SGVPIIAANMDTVGTFSMASALASFDILTAVHKHYSVEEWQAFINNSSADVLKHVMVS
                     TGTSDADFEKTKQILDLNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVV
                     TGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIIS
                     DGGCTTPGDVAKAFGGGADFVMLGGMLAGHEESGGRIVEENGEKFMLFYGMSSESAMK
                     RHVGGVAEYRAAEGKTVKLPLRGPVENTARDILGGLRSACTYVGASRLKELTKRTTFI
                     RVQEQENRIFNNL"
     misc_feature    117934..118971
                     /gene="guaC"
                     /locus_tag="ECs_0108"
                     /note="guanosine 5'-monophosphate oxidoreductase;
                     Provisional; Region: PRK05096"
                     /db_xref="CDD:235343"
     gene            complement(119012..120214)
                     /gene="hofC"
                     /locus_tag="ECs_0110"
                     /db_xref="GeneID:913621"
     CDS             complement(119012..120214)
                     /gene="hofC"
                     /locus_tag="ECs_0110"
                     /codon_start=1
                     /transl_table=11
                     /product="assembly protein in type IV pilin biogenesis
                     transmembrane protein"
                     /protein_id="NP_308137.1"
                     /db_xref="GeneID:913621"
                     /translation="MASKQLWRWHGITGDGNAQDGMLWAESRTLLLMALQQQMVTPLS
                     LKRIAINSAQWRGDKSAEVIHQLATLLKAGLTLSEGLALLAEQHPSKQWQALLQSLAH
                     DLEQGIAFSNALLPWSEVFPPLYQAMIRTGELTGKLDECCFELARQQRAQRQLTDKVK
                     SALRYPIIILAMAIMVVVAMLHFVLPEFAAIYKTFNTPLPALTQGIMTLADFSGEWGW
                     LLVLFGIMLTIANKLLMRRPTWLIARQKLLLRIPIMGSLMRGQKLTQIFTILALTQSA
                     GITFLQGVESVRETMRCPYWVQLLTQIQHDISNGHPIWLALKNAGEFSPLCLQLVRTG
                     EASGSLDLMLDNIAHHHRDNTMALADNLAALLEPALLIITGGIIGTLVVAMYLPIFHL
                     GDAMSGMG"
     misc_feature    complement(119024..120214)
                     /gene="hofC"
                     /locus_tag="ECs_0110"
                     /note="protein transport protein HofC; Region: PRK10573"
                     /db_xref="CDD:182559"
     gene            complement(120204..121589)
                     /gene="hofB"
                     /locus_tag="ECs_0111"
                     /db_xref="GeneID:913626"
     CDS             complement(120204..121589)
                     /gene="hofB"
                     /locus_tag="ECs_0111"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein HofB"
                     /protein_id="NP_308138.1"
                     /db_xref="GeneID:913626"
                     /translation="MNIPQLTALCLRYQGVLLDASEEVVHVAVVDAPSHELLDALHFA
                     TTKRIEITCWTRQQMEGHASRTQQTLPVAVQEKHQPKAELLTRTLQSALEQRASDIHI
                     EPADNAYRIRLRIDGVLHPLPDVSPDAGVALTARLKVLGNLDIAEHRLPQDGQFTVEL
                     AGNAVSFRIATLPCRGGEKVVLRLLQQVSQALDVNTLGMQPLQLAGFAHALQQPQGLV
                     LVTGPTGSGKTVTLYSALQKLNTADINICSVEDPVEIPIAGLNQTQIHPRAGLTFQGV
                     LRALLRQDPDVIMIGEIRDGETAEIAIKAAQTGHLVLSTLHTNSTCETLVRLQQMGVA
                     RWMLSSALTLVIAQRLVRKLCPHCRRQQGEPIHIPVNVWPSPLPHWQAPGCVHCYHGF
                     YGRTALFEVLPITPVIRQLISANTDVESLETHARQAGMRTLFENGCLAVEQGLTTFEE
                     LIRVLGMPHGE"
     misc_feature    complement(120213..121589)
                     /gene="hofB"
                     /locus_tag="ECs_0111"
                     /note="hypothetical protein; Provisional; Region:
                     PRK10436"
                     /db_xref="CDD:236694"
     gene            complement(121599..122039)
                     /gene="ppdD"
                     /locus_tag="ECs_0112"
                     /db_xref="GeneID:913629"
     CDS             complement(121599..122039)
                     /gene="ppdD"
                     /locus_tag="ECs_0112"
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent pilin"
                     /protein_id="NP_308139.1"
                     /db_xref="GeneID:913629"
                     /translation="MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQ
                     TFVPYRTAVELCALEHGGLDTCDGGSNGIPSPTTTRYVSAMSVAKGVVSLTGQESLNG
                     LSVVMTPGWDNANGVTGWARNCNIQSDSALQQACEDVFRFDDAN"
     misc_feature    complement(121602..122039)
                     /gene="ppdD"
                     /locus_tag="ECs_0112"
                     /note="putative major pilin subunit; Provisional; Region:
                     PRK10574"
                     /db_xref="CDD:236718"
     gene            complement(122242..123135)
                     /gene="nadC"
                     /locus_tag="ECs_0113"
                     /db_xref="GeneID:913630"
     CDS             complement(122242..123135)
                     /gene="nadC"
                     /locus_tag="ECs_0113"
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate phosphoribosyltransferase"
                     /protein_id="NP_308140.1"
                     /db_xref="GeneID:913630"
                     /translation="MPPRRYNPDTRRDELLERINLDIPGAVAQALREDLGGTVDANND
                     ITAKLLPENSRSHATVITRENGVFCGKRWVEEVFIQLAGDDVTIIWHVDDGDVINANQ
                     PLFELEGPSRVLLTGERTALNFVQTLSGVASKVRHYVELLEGTNTQLLDTRKTLPGLR
                     SALKYAVLCGGGANHRLGLSDAFLIKENHIIASGSVRQAVEKASWLHPDAPVEVEVEN
                     LEELDEALKAGADIIMLDNFETEQMREAVKRTNGKALLEVSGNVTDKTLREFAETGVD
                     FISVGALTKHVQALDLSMRFR"
     misc_feature    complement(122251..123060)
                     /gene="nadC"
                     /locus_tag="ECs_0113"
                     /note="Quinolinate phosphoribosyl transferase (QAPRTase or
                     QPRTase), also called nicotinate-nucleotide
                     pyrophosphorylase, is involved in the de novo synthesis of
                     NAD in both prokaryotes and eukaryotes. It catalyses the
                     reaction of quinolinic acid (QA) with...; Region: QPRTase;
                     cd01572"
                     /db_xref="CDD:238806"
     misc_feature    complement(order(122281..122283,122527..122529,
                     122560..122562,122569..122574,122578..122580,
                     122584..122586,122596..122601,122656..122661,
                     122671..122673,122677..122679,122767..122769,
                     122779..122784,122995..123000))
                     /gene="nadC"
                     /locus_tag="ECs_0113"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238806"
     misc_feature    complement(order(122281..122283,122290..122295,
                     122299..122301,122356..122361,122428..122430,
                     122608..122613,122674..122682))
                     /gene="nadC"
                     /locus_tag="ECs_0113"
                     /note="active site"
                     /db_xref="CDD:238806"
     gene            123223..123774
                     /gene="ampD"
                     /locus_tag="ECs_0114"
                     /db_xref="GeneID:913635"
     CDS             123223..123774
                     /gene="ampD"
                     /locus_tag="ECs_0114"
                     /codon_start=1
                     /transl_table=11
                     /product="1,6-anhydro-N-acetylmuramyl-L-alanine amidase"
                     /protein_id="NP_308141.1"
                     /db_xref="GeneID:913635"
                     /translation="MLLEQGWLVGARRVPSPHYDCRPDDETPTLLVVHNISLPPGEFG
                     GPWIDALFTGTIDPQAHPFFAEIAHLRVSAHCLIRRDGEIVQYVPFDKRAWHAGVSQY
                     QGRERCNDFSIGIELEGTDTLAYTDAQYQQLAAVTRALIDCYPDIANNMTGHCDIAPD
                     RKTDPGPAFDWARFRALVSKETT"
     misc_feature    123223..123771
                     /gene="ampD"
                     /locus_tag="ECs_0114"
                     /note="1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD;
                     Region: PRK11789"
                     /db_xref="CDD:236984"
     misc_feature    order(123322..123324,123442..123444,123682..123684,
                     123706..123708,123712..123714)
                     /gene="ampD"
                     /locus_tag="ECs_0114"
                     /note="amidase catalytic site [active]"
                     /db_xref="CDD:133475"
     misc_feature    order(123322..123324,123682..123684,123712..123714)
                     /gene="ampD"
                     /locus_tag="ECs_0114"
                     /note="Zn binding residues [ion binding]; other site"
                     /db_xref="CDD:133475"
     misc_feature    order(123325..123330,123400..123402,123442..123444,
                     123484..123486,123505..123510,123547..123549,
                     123682..123684,123694..123696,123706..123714)
                     /gene="ampD"
                     /locus_tag="ECs_0114"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:133475"
     gene            123771..124625
                     /gene="ampE"
                     /locus_tag="ECs_0115"
                     /db_xref="GeneID:913637"
     CDS             123771..124625
                     /gene="ampE"
                     /locus_tag="ECs_0115"
                     /codon_start=1
                     /transl_table=11
                     /product="ampicillin resistance inner membrane protein
                     AmpE"
                     /protein_id="NP_308142.1"
                     /db_xref="GeneID:913637"
                     /translation="MTLFTTLLVLIFERLFKLGEHWQLDHRLEAFFRRVKHFSLGRTL
                     GMTIIAMGVTFLLLRALQGVLFNVPTLLVWLLIGLLCIGAGKVRLHYHAYLTAASRND
                     SHARATMAGELTMIHGVPAGCDEREYLRELQNALLWINFRFYLAPLFWLIVGGTWGPV
                     TLMGYAFLRAWQYWLARYQTPHHRLQSGIDAVLHVLDWVPVRLAGVVYALIGHGEKAL
                     PAWFASLGDFRTSQYQVLTRLAQFSLAREPHVDKVETPKAAVSMAKKTSFVVVVVIAL
                     LTIYGALV"
     misc_feature    123771..124622
                     /gene="ampE"
                     /locus_tag="ECs_0115"
                     /note="Regulatory signalling modulator protein AmpE;
                     Region: AmpE; pfam17113"
                     /db_xref="CDD:374997"
     gene            complement(124668..126038)
                     /gene="aroP"
                     /locus_tag="ECs_0116"
                     /db_xref="GeneID:913640"
     CDS             complement(124668..126038)
                     /gene="aroP"
                     /locus_tag="ECs_0116"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine transporter"
                     /protein_id="NP_308143.2"
                     /db_xref="GeneID:913640"
                     /translation="MEGQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSAG
                     PGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGSFAGFASGWNYWVLY
                     VLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVTVFGEMEFWFAIIKV
                     IAVVAMIIFGGWLLFSGNGGPQASVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLEL
                     VGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIFH
                     ELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALASVDKRGVPVN
                     TILVSALVTALCVLINYLAPESAFGLLMALVVSALVINWAMISLAHMKFRRAKQEQGV
                     VTRFPALLYPLGNWICLLFMAVVLVIMLMTPGMAISVYLIPVWLVVLGIGYLFKEKTA
                     KAVKAH"
     misc_feature    complement(124671..126038)
                     /gene="aroP"
                     /locus_tag="ECs_0116"
                     /note="aromatic amino acid transporter AroP; Region:
                     PRK10238"
                     /db_xref="CDD:182324"
     gene            126582..127346
                     /gene="pdhR"
                     /locus_tag="ECs_0117"
                     /db_xref="GeneID:913643"
     CDS             126582..127346
                     /gene="pdhR"
                     /locus_tag="ECs_0117"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex repressor"
                     /protein_id="NP_308144.1"
                     /db_xref="GeneID:913643"
                     /translation="MAYSKIRQPKLSDVIEQQLEFLILEGTLRPGEKLPPERELAKQF
                     DVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSLWQSFSDPLVELLSDHPESQYDLLE
                     TRHALEGIAAYYAALRSTDEDKERIRELHHAIELAQQSGDLDAESNAVLQYQIAVTEA
                     AHNVVLLHLLRCMEPMLAQNVRQNFELLYSRREMLPLVSSHRTRIFEAIMAGKPEEAR
                     EASHRHLAFIEEILLDRSREESRRERSLRRLEQRKN"
     misc_feature    126582..127283
                     /gene="pdhR"
                     /locus_tag="ECs_0117"
                     /note="pyruvate dehydrogenase complex transcriptional
                     repressor PdhR; Region: pdhR; PRK09464"
                     /db_xref="CDD:181879"
     gene            127507..130170
                     /gene="aceE"
                     /locus_tag="ECs_0118"
                     /db_xref="GeneID:913657"
     CDS             127507..130170
                     /gene="aceE"
                     /locus_tag="ECs_0118"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase"
                     /protein_id="NP_308145.1"
                     /db_xref="GeneID:913657"
                     /translation="MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEA
                     RKGGVNVAAGTGISNYINTIPVEEQPEYPGNLELERRIRSAIRWNAIMTVLRASKKDL
                     ELGGHMASFQSSATIYDVCFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTQ
                     EQLDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLK
                     DTSKQTVYAFLGDGEMDEPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKII
                     NELEGIFEGAGWNVIKVMWGSRWDELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYV
                     REHFFGKYPETAALVADWTDEQIWALNRGGHDPKKIYAAFKKAQETKGKATVILAHTI
                     KGYGMGDAAEGKNIAHQVKKMNMDGVRHIRDRFNVPVSDADIEKLPYITFPEGSEEHT
                     YLHAQRQKLHGYLPSRQPNFTEKLELPSLQDFGALLEEQSKEISTTIAFVRALNVMLK
                     NKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQQYTPQDREQVAYYKEDEKGQIL
                     QEGINELGAGCSWLAAATSYSTNNLPMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFL
                     IGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEK
                     QENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETIEGSKGKVQLLGSGSILRHVR
                     EAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPA
                     VASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGE
                     LAKRGEIDKKVVADAIAKFNIDADKVNPRLA"
     misc_feature    127507..130167
                     /gene="aceE"
                     /locus_tag="ECs_0118"
                     /note="pyruvate dehydrogenase subunit E1; Reviewed;
                     Region: aceE; PRK09405"
                     /db_xref="CDD:236500"
     gene            130185..132077
                     /gene="aceF"
                     /locus_tag="ECs_0119"
                     /db_xref="GeneID:913659"
     CDS             130185..132077
                     /gene="aceF"
                     /locus_tag="ECs_0119"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase"
                     /protein_id="NP_308146.1"
                     /db_xref="GeneID:913659"
                     /translation="MAIEIKVPDIGADEVEITEILVKVGDKVEAEQSLITVEGDKASM
                     EVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGAADAAPAQAEEKKEAAPAAVPEA
                     AAAKDVNVPDIGSDEVEVTEILVKVGDKVEAEQSLITVEGDKASMEVPAPFAGTVKEI
                     KVNTGDKVSTGSLIMVFEVAGEAGAAAPAAKQEAAPAAAPAPAAGVKEVNVPDIGGDE
                     VEVTEVMVKVGDKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIM
                     IFEVEGAAPAAAPAKQEAAAPAPAAKAEAPAAAPAAKAEGKSEFAENDAYVHATPLIR
                     RLAREFGVNLAKVKGTGRKGRILREDVQAYVKEAIKRAEAAPAATGGGIPGMLPWPKV
                     DFSKFGEIEEVELGRIQKISGANLSRNWVMIPHVTHFDKTDITELEAFRKQQNEEAAK
                     RKLDVKITPVVFIMKAVAAALEQMPRFNSSLSEDGQRLTLKKYINIGVAVDTPNGLVV
                     PVFKDVNKKGIIELSRELMTISKKARDGKLTAGEMQGGCFTISSIGGLGTTHFAPIVN
                     APEVAILGVSKSAMEPVWNGKEFVPRLMLPISLSFDHRVIDGADGARFITIINNTLSD
                     IRRLVM"
     misc_feature    130185..132074
                     /gene="aceF"
                     /locus_tag="ECs_0119"
                     /note="pyruvate dehydrogenase dihydrolipoyltransacetylase;
                     Validated; Region: aceF; PRK11854"
                     /db_xref="CDD:236999"
     gene            132285..133709
                     /gene="lpd"
                     /locus_tag="ECs_0120"
                     /db_xref="GeneID:913660"
     CDS             132285..133709
                     /gene="lpd"
                     /locus_tag="ECs_0120"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="NP_308147.1"
                     /db_xref="GeneID:913660"
                     /translation="MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGV
                     CLNVGCIPSKALLHVAKVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLA
                     GMAKGRKVKVVNGLGKFTGANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDP
                     RIWDSTDALELKEVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDI
                     VKVFTKRISKKFNLMLETKVTAVEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPN
                     GKNLDAGKAGVEVDDRGFIRVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEV
                     IAGKKHYFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETATFPWAASGRAIASDC
                     ADGMTKLIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHE
                     SVGLAAEVFEGSITDLPNPKAKKK"
     misc_feature    132291..133652
                     /gene="lpd"
                     /locus_tag="ECs_0120"
                     /note="Pyruvate/2-oxoglutarate dehydrogenase complex,
                     dihydrolipoamide dehydrogenase (E3) component or related
                     enzyme [Energy production and conversion]; Region: Lpd;
                     COG1249"
                     /db_xref="CDD:224169"
     gene            complement(133780..135633)
                     /gene="yacH"
                     /locus_tag="ECs_0121"
                     /db_xref="GeneID:913666"
     CDS             complement(133780..135633)
                     /gene="yacH"
                     /locus_tag="ECs_0121"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308148.1"
                     /db_xref="GeneID:913666"
                     /translation="MKMTLPFKPHVLALICSAGLCAASAGLYIKSRTVEAPVETQSTQ
                     LAVSDAAAVTLPATVSAPPVTPAVVKSAFSTAQIDQWVAPVALYPDALLSQVLMASTY
                     PTNVAQAVQWSHDNPLKQGDAAIQAVSDQPWDASVKSLVAFPQLMALMGENPQWVQNL
                     GDAFLAQPQDVMDSVQRLRQLAQQTGSLKSSTEQKVITTTKKTVPVTQTVTAPVIPSN
                     TVSTANPVITEPATTVISIEPGNPDVVYIPNYNPTVVYGNWANTAYPPVYLPPPAGEP
                     FVDSFVRGFGYSMGVATTYALFSSIDWDDDDHDHHHHDDDNYHHHDGGHRDGNGWQHN
                     GDNINIDVNNFNRITGEHLTDKNMAWRHNPNYRNGVPYHDQDMAKRFHQTDVNGGMSA
                     TQLPAPTRDSQRQAAASQFQQRTHAAPVITRDTQRQAAAQRFNEAEHYGSYDDFRDFS
                     RRQPLTQQQKDAARQRYQSASPEQRQAVHEKMQTNPQNQQRREAARERIQPASPEQRQ
                     AVREKMQTNPQIQQRRDAARERIQSASPEQRQVFKEKVQQRPLNQQQRDNARQRVQSA
                     SPEQRQVFREKVQESRPQRLNDSNHTARLNNEQRSAVRERLSERGARRLER"
     misc_feature    complement(134515..135414)
                     /gene="yacH"
                     /locus_tag="ECs_0121"
                     /note="Protein of unknown function (DUF3300); Region:
                     DUF3300; pfam11737"
                     /db_xref="CDD:432035"
     misc_feature    complement(<133783..134448)
                     /gene="yacH"
                     /locus_tag="ECs_0121"
                     /note="transcription termination factor Rho; Provisional;
                     Region: PRK12678"
                     /db_xref="CDD:237171"
     gene            135988..138585
                     /gene="acnB"
                     /locus_tag="ECs_0122"
                     /db_xref="GeneID:913670"
     CDS             135988..138585
                     /gene="acnB"
                     /locus_tag="ECs_0122"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase"
                     /protein_id="NP_308149.1"
                     /db_xref="GeneID:913670"
                     /translation="MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEF
                     LLDLLTNRVPPGVDEAAYVKAGFLAAVAKGEAKSPLLTPEKAIELLGTMQGGYNIHPL
                     IDALDDAKLAPIAAKALSHTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRP
                     ALAEKLTVTVFKVTGETNTDDLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVG
                     PIKQIEALQQKGFPLAYVGDVVGTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGG
                     KIAPIFFNTMEDAGALPIEVDVSNLNMGDVIDVYPYKGEVRNHETGELLATFELKTDV
                     LIDEVRAGGRIPLIIGRGLTTKAREALGLPHSDVFRQAKDVAESDRGFSLAQKMVGRA
                     CGVKGIRPGAYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPK
                     PVDVNTHHTLPDFIMNRGGVSLRPGDGVIHSWLNRMLLPDTVGTGGDSHTRFPIGISF
                     PAGSGLVAFAAATGVMPLDMPESVLVRFKGKMQPGITLRDLVHAIPLYAIKQGLLTVE
                     KKGKKNIFSGRILEIEGLPDLKVEQAFELTDASAERSAAGCTIKLNKEPIIEYLNSNI
                     VLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEADADAEYAAVIDIDLADIKEPIL
                     CAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAAGKLLDAHKGQLPTRLWVAPP
                     TRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVADGATVVSTSTRNFPNRLG
                     TGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDTYRYLNFNQLSQYTEKA
                     DGVIFQTAV"
     misc_feature    135988..138525
                     /gene="acnB"
                     /locus_tag="ECs_0122"
                     /note="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase; Validated; Region:
                     PRK09238"
                     /db_xref="CDD:236424"
     gene            138761..139123
                     /gene="yacL"
                     /locus_tag="ECs_0123"
                     /db_xref="GeneID:913686"
     CDS             138761..139123
                     /gene="yacL"
                     /locus_tag="ECs_0123"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308150.2"
                     /db_xref="GeneID:913686"
                     /translation="MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEQ
                     AAHALKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCG
                     VEDFLQVVAAYRNFVQQK"
     misc_feature    138761..139120
                     /gene="yacL"
                     /locus_tag="ECs_0123"
                     /note="Uncharacterized protein YacL, UPF0231 family
                     [Function unknown]; Region: YacL; COG3112"
                     /db_xref="CDD:225654"
     gene            complement(139161..139955)
                     /gene="speD"
                     /locus_tag="ECs_0124"
                     /db_xref="GeneID:913693"
     CDS             complement(139161..139955)
                     /gene="speD"
                     /locus_tag="ECs_0124"
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine decarboxylase"
                     /protein_id="NP_308151.1"
                     /db_xref="GeneID:913693"
                     /translation="MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYN
                     ANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLP
                     ETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDI
                     VTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSDDMKALYDMVDVNVYQENIFHTKML
                     LKEFDLKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV"
     misc_feature    complement(139164..139955)
                     /gene="speD"
                     /locus_tag="ECs_0124"
                     /note="adenosylmethionine decarboxylase; Region: PRK05462"
                     /db_xref="CDD:235480"
     gene            complement(139971..140837)
                     /gene="speE"
                     /locus_tag="ECs_0125"
                     /db_xref="GeneID:913703"
     CDS             complement(139971..140837)
                     /gene="speE"
                     /locus_tag="ECs_0125"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine synthase"
                     /protein_id="NP_308152.1"
                     /db_xref="GeneID:913703"
                     /translation="MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFG
                     RVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVE
                     SITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCT
                     DPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGF
                     YQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAVHTAAFALP
                     QYLQDALASQPS"
     misc_feature    complement(139986..140819)
                     /gene="speE"
                     /locus_tag="ECs_0125"
                     /note="polyamine aminopropyltransferase; Region: PRK00811"
                     /db_xref="CDD:234843"
     misc_feature    complement(order(140364..140366,140415..140423,
                     140511..140516,140568..140588))
                     /gene="speE"
                     /locus_tag="ECs_0125"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            complement(140943..141251)
                     /gene="yacC"
                     /locus_tag="ECs_0126"
                     /db_xref="GeneID:913704"
     CDS             complement(140943..141251)
                     /gene="yacC"
                     /locus_tag="ECs_0126"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308153.3"
                     /db_xref="GeneID:913704"
                     /translation="MAVCANSYALSESEAEDMADLTAVFVFLKNDCGYQNLPNGQIRR
                     ALVFFAQQNQWDLSNYDTFDMKALGEDSYRDLSGIGIPVAKKCKALARDSLSLLAYVK
                     "
     misc_feature    complement(140946..141251)
                     /gene="yacC"
                     /locus_tag="ECs_0126"
                     /note="YacC family pilotin-like protein; Region:
                     pilot_rel_YacC; NF037975"
                     /db_xref="CDD:411579"
     gene            141456..143006
                     /gene="cueO"
                     /locus_tag="ECs_0127"
                     /db_xref="GeneID:913706"
     CDS             141456..143006
                     /gene="cueO"
                     /locus_tag="ECs_0127"
                     /codon_start=1
                     /transl_table=11
                     /product="multicopper oxidase"
                     /protein_id="NP_308154.1"
                     /db_xref="GeneID:913706"
                     /translation="MQRRDFLKYSVALGVASALPLWSRAVFAAERPTLPIPDLLTTDA
                     RNRIQLTIGAGQSTFGEKTATTWGYNGNLLGPAVKLQRGKAVTVDIYNQLTEETTLHW
                     HGLEVPGEVDGGPQGIIPPGGKRSVTLNVDQPAATCWFHPHQHGKTGRQVAMGLAGLV
                     VIEDDEILKLMLPKQWGIDDVPVIVQDKKFSADGQIDYQLDVMTAAVGWFGDTLLTNG
                     AIYPQHAAPRGWLRLRLLNGCNARSLNFATSDNRPLYVIASDGGLLPEPVKVNELPVL
                     MGERFEVLVEVNDNKPFDLVTLPVSQMGMAIAPFDKPHPVMRIQPIAISASGALPDTL
                     SSLPALPSLEGLTVRKLQLSMDPMLDMMGMQMLMEKYGDQAMVGMDHSQMMGHMGHGN
                     MNHMNHGGKFDFHHANKINGQAFDMNKPMFAAAKGQYERWVISGVGDMMLHPFHIHGT
                     QFRILSENGKPPAAHRAGWKDTVKVEGNVSEVLVKFNHDAPKERAYMAHCHLLEHEDT
                     GMMLGFTV"
     misc_feature    141456..143003
                     /gene="cueO"
                     /locus_tag="ECs_0127"
                     /note="multicopper oxidase; Provisional; Region: PRK10965"
                     /db_xref="CDD:236810"
     gene            complement(143208..145598)
                     /gene="gcd"
                     /locus_tag="ECs_0128"
                     /db_xref="GeneID:913709"
     CDS             complement(143208..145598)
                     /gene="gcd"
                     /locus_tag="ECs_0128"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose dehydrogenase"
                     /protein_id="NP_308155.1"
                     /db_xref="GeneID:913709"
                     /translation="MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYP
                     IAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGI
                     WLILPFVWRRLVIPASGAVAALVVALLISGSILTWAGFNDPQEINGTLSADATPAEAI
                     SPVADQDWPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKQPNDPGEITNEV
                     TPIKVGDTLYLCTAHQRLFALDAASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAE
                     TASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNLQSNMPDTKPGLYE
                     PTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSD
                     EHTFTFNSPNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATT
                     GKLAWSYQTVHHDLWDMDLPAQPTLADITVNGQKVPVIYAPAKTGNIFVLDRRNGELV
                     VPAPEKPVPQGAAKGDYVTPTQPFSELSFRPTKDLSGADMWGATMFDQLVCRVMFHQM
                     RYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGN
                     PMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEV
                     VWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAGNVLFIAATADNYLRAYNMSN
                     GEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK"
     misc_feature    complement(143220..145568)
                     /gene="gcd"
                     /locus_tag="ECs_0128"
                     /note="Glucose dehydrogenase [Carbohydrate transport and
                     metabolism]; Region: Gcd; COG4993"
                     /db_xref="CDD:227326"
     gene            145804..146340
                     /gene="hpt"
                     /locus_tag="ECs_0129"
                     /db_xref="GeneID:913711"
     CDS             145804..146340
                     /gene="hpt"
                     /locus_tag="ECs_0129"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="NP_308156.2"
                     /db_xref="GeneID:913711"
                     /translation="MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRG
                     SFMFMADLCREVQVSHEVDFMTASSYGSGMSTTRDVKILKDLDEDIRGKDVLIVEDII
                     DSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDY
                     AQRYRHLPYIGKVILLDE"
     misc_feature    145804..146337
                     /gene="hpt"
                     /locus_tag="ECs_0129"
                     /note="hypoxanthine phosphoribosyltransferase;
                     Provisional; Region: PRK15423"
                     /db_xref="CDD:185321"
     misc_feature    order(145927..145929,145933..145935,146098..146106,
                     146110..146124,146194..146196)
                     /gene="hpt"
                     /locus_tag="ECs_0129"
                     /note="active site"
                     /db_xref="CDD:206754"
     gene            complement(146381..147043)
                     /gene="can"
                     /locus_tag="ECs_0130"
                     /db_xref="GeneID:913712"
     CDS             complement(146381..147043)
                     /gene="can"
                     /locus_tag="ECs_0130"
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="NP_308157.1"
                     /db_xref="GeneID:913712"
                     /translation="MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSD
                     SRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHYGCG
                     GVQAAVENPELGLINNWLLHIRDIWFKHSSLLDEMPQERRLDTLCELNVMEQVYNLGH
                     STIMQSAWKRGQKVTIHGWAYGIHDGLLRDLDVTATNRETLEQRYRHGISNLKLKHAN
                     HK"
     misc_feature    complement(146384..147043)
                     /gene="can"
                     /locus_tag="ECs_0130"
                     /note="carbonic anhydrase; Provisional; Region: PRK10437"
                     /db_xref="CDD:182460"
     misc_feature    complement(order(146501..146503,146741..146743,
                     146750..146752,146780..146782,146795..146797,
                     146861..146863,146870..146872,146906..146914,
                     146918..146920,146939..146941,146945..146947))
                     /gene="can"
                     /locus_tag="ECs_0130"
                     /note="active site clefts [active]"
                     /db_xref="CDD:238448"
     misc_feature    complement(order(146741..146743,146750..146752,
                     146912..146914,146918..146920))
                     /gene="can"
                     /locus_tag="ECs_0130"
                     /note="zinc binding site [ion binding]; other site"
                     /db_xref="CDD:238448"
     misc_feature    complement(order(146480..146482,146486..146488,
                     146492..146497,146501..146503,146687..146689,
                     146795..146800,146807..146812,146852..146854,
                     146858..146860,146864..146872,146885..146887,
                     146891..146896,146900..146902,146906..146917))
                     /gene="can"
                     /locus_tag="ECs_0130"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238448"
     gene            147152..148078
                     /gene="yadG"
                     /locus_tag="ECs_0131"
                     /db_xref="GeneID:913713"
     CDS             147152..148078
                     /gene="yadG"
                     /locus_tag="ECs_0131"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATPase"
                     /protein_id="NP_308158.1"
                     /db_xref="GeneID:913713"
                     /translation="MTIALELQQLKKNYPGGVQALRGIDLQVEAGDFYALLGPNGAGK
                     STTIGIISSLVNKTSGRVSVFGYDLEKDVVNAKRQLGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVERKEAYIRSEKYLKQLDLWGKRNERARMLSGGMKRRLMIARALMHEPKLLIL
                     DEPTAGVDIELRRSMWGFLKDLNDKGTTIILTTHYLEEAEMLCRNIGIIQHGELVENT
                     SMKALLAKLKSETFILDLAPKSPLPKLDGYQYRLVDTATLEVEVLREQGINSVFTQLS
                     EQGIQVLSMRNKANRLEELFVSLVNEKQGDRA"
     misc_feature    147152..148057
                     /gene="yadG"
                     /locus_tag="ECs_0131"
                     /note="ABC-type multidrug transport system, ATPase
                     component [Defense mechanisms]; Region: CcmA; COG1131"
                     /db_xref="CDD:224054"
     gene            148075..148845
                     /gene="yadH"
                     /locus_tag="ECs_0132"
                     /db_xref="GeneID:913717"
     CDS             148075..148845
                     /gene="yadH"
                     /locus_tag="ECs_0132"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="NP_308159.1"
                     /db_xref="GeneID:913717"
                     /translation="MMHLYWVALKSIWAKEIHRFMRIWVQTLVPPVITMTLYFIIFGN
                     LIGSRIGDMHGFSYMQFIVPGLIMMSVITNAYANVASSFFGAKFQRNIEELLVAPVPT
                     HVIIAGYVGGGVARGLFVGILVTAISLFFVPFQVHSWVFVALTLVLTAVLFSLAGLLN
                     GVFAKTFDDISLVPTFVLTPLTYLGGVFYSLTLLPPFWQGLSHLNPIVYMISGFRYGF
                     LGINDVPLVTTFGVLVVFIVAFYLICWSLIQRGRGLRS"
     misc_feature    148075..148842
                     /gene="yadH"
                     /locus_tag="ECs_0132"
                     /note="inner membrane transport permease; Provisional;
                     Region: PRK15066"
                     /db_xref="CDD:237896"
     gene            148950..149390
                     /gene="yadI"
                     /locus_tag="ECs_0133"
                     /db_xref="GeneID:913720"
     CDS             148950..149390
                     /gene="yadI"
                     /locus_tag="ECs_0133"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS Enzyme IIA"
                     /protein_id="NP_308160.1"
                     /db_xref="GeneID:913720"
                     /translation="MLGWVITCHDDRAQEILDVLEKKHGALLQCRAVNFWRGLSSNML
                     SRMMCDALHEADSGEGVIFLTDIAGAPPYRVASLLSHKHSRCEVISGVTLPLIEQMMA
                     CRETMTSSEFRERIVELGAPEVSSIWHQQQKNPPFVLKHNLYEY"
     misc_feature    148950..149372
                     /gene="yadI"
                     /locus_tag="ECs_0133"
                     /note="Phosphotransferase system,
                     mannose/fructose-specific component IIA [Carbohydrate
                     transport and metabolism]; Region: ManX; COG2893"
                     /db_xref="CDD:225446"
     gene            149454..150683
                     /gene="yadE"
                     /locus_tag="ECs_0134"
                     /db_xref="GeneID:913723"
     CDS             149454..150683
                     /gene="yadE"
                     /locus_tag="ECs_0134"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase lipoprotein"
                     /protein_id="NP_308161.1"
                     /db_xref="GeneID:913723"
                     /translation="MYKQAVILLLMLFTASVSAALPARYMQTIENAAVWAQIGDKMVT
                     VGNIRAGQIIAVEPTAASYYAFNFGFDKGFIDKGHLEPVQGRQKVEDGLGDLNKPLSN
                     QNLVTWKDTPVYNAPSVGSAPFGVLADNLRYPILHKLKDRLNQTWYQIRIGDRLAYIS
                     ALDAQPDNGLPVLTYHHILRDEENTRFRHTSTTTSVRAFNNQMAWLRDRGYATLSMVQ
                     LEGYVKNKINLPARAVVITFDDGLKSVSRYAYPVLKQYGMKATAFIVTSRIKRHPQKW
                     EPKSLQFMSVSELNEIRDVFDFQSHTHFLHRVDGYRRPILLSRSEHNILFDFARSRRA
                     LAQFNPHVWYLSYPFGGFNDKAVKAANDAGFHLAVTTMKGKVKPGDNPLLLKRLYILR
                     TDSLETMSRLVSNQPQG"
     misc_feature    150141..150650
                     /gene="yadE"
                     /locus_tag="ECs_0134"
                     /note="Putative catalytic polysaccharide deacetylase
                     domain of uncharacterized protein yadE and similar
                     proteins; Region: CE4_yadE_5s; cd10966"
                     /db_xref="CDD:213024"
     misc_feature    order(150168..150173,150354..150356,150369..150371,
                     150495..150503)
                     /gene="yadE"
                     /locus_tag="ECs_0134"
                     /note="putative active site [active]"
                     /db_xref="CDD:213024"
     gene            complement(150687..151067)
                     /gene="panD"
                     /locus_tag="ECs_0135"
                     /db_xref="GeneID:913727"
     CDS             complement(150687..151067)
                     /gene="panD"
                     /locus_tag="ECs_0135"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="NP_308162.1"
                     /db_xref="GeneID:913727"
                     /translation="MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAI
                     DIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWR
                     PNVAYFEGDNEMKRTAKAIPVQVA"
     misc_feature    complement(150690..151067)
                     /gene="panD"
                     /locus_tag="ECs_0135"
                     /note="L-aspartate-alpha-decarboxylase; Region: panD;
                     TIGR00223"
                     /db_xref="CDD:129327"
     misc_feature    complement(order(150765..150767,150792..150800,
                     150810..150812,150834..150839,150843..150848,
                     150894..150908,150912..150914,150921..150923,
                     150927..150929,150939..150944,150951..150953,
                     150957..150959,150999..151010,151032..151037,
                     151041..151043,151047..151061))
                     /gene="panD"
                     /locus_tag="ECs_0135"
                     /note="tetramerization interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:132994"
     misc_feature    complement(order(150894..150896,150993..150998,
                     151035..151037,151041..151043))
                     /gene="panD"
                     /locus_tag="ECs_0135"
                     /note="active site"
                     /db_xref="CDD:132994"
     gene            151341..152237
                     /gene="yadD"
                     /locus_tag="ECs_0136"
                     /db_xref="GeneID:913728"
     CDS             151341..152237
                     /gene="yadD"
                     /locus_tag="ECs_0136"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308163.1"
                     /db_xref="GeneID:913728"
                     /translation="MDAPSTTPHDAVFKQFLMHAETARDFLEIHLPVELRELCDLNTL
                     HLESGSFIEESLKGHSTDVLYSVQMQGNPGYLHVVIEHQSKPDKKMAFRMMRYSIAAM
                     HRHLEADHDKLPLVVPILFYQGEATPYPLSMCWFDMFYSPELARRVYNSPFPLVDITI
                     TPDDEIMQHRRIAILELLQKHIRQRDLMLLLEQLVTLIDEGYTSESQLVAMQNYMLQR
                     GHTEQADLFYGVLRDRETGGKSMMTLAQWFEEKGIEKGIQQGRQEERQEFAQRFLSKG
                     MSREDVAEMTNLSLAEIDRLIN"
     misc_feature    151359..152228
                     /gene="yadD"
                     /locus_tag="ECs_0136"
                     /note="Predicted transposase YdaD [Replication,
                     recombination and repair]; Region: YadD; COG5464"
                     /db_xref="CDD:227751"
     gene            complement(152536..153387)
                     /gene="panC"
                     /locus_tag="ECs_0137"
                     /db_xref="GeneID:913734"
     CDS             complement(152536..153387)
                     /gene="panC"
                     /locus_tag="ECs_0137"
                     /codon_start=1
                     /transl_table=11
                     /product="pantothenate synthetase"
                     /protein_id="NP_308164.1"
                     /db_xref="GeneID:913734"
                     /translation="MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEA
                     KARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYPNG
                     TETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIR
                     KMVADMGFDIEIVGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAG
                     ERDLDEIIAIAGQELNEKGFRADDIQIRDADTLLEVSETSKRAVILVAAWLGDARLID
                     NKMVELA"
     misc_feature    complement(152557..153387)
                     /gene="panC"
                     /locus_tag="ECs_0137"
                     /note="Pantoate-beta-alanine ligase; Region: PanC;
                     cd00560"
                     /db_xref="CDD:185673"
     misc_feature    complement(order(152821..152832,152854..152862,
                     152923..152925,152932..152937,152941..152946,
                     152986..152991,152998..153000,153175..153177,
                     153205..153207,153214..153216,153268..153270,
                     153277..153282,153286..153288,153295..153306))
                     /gene="panC"
                     /locus_tag="ECs_0137"
                     /note="active site"
                     /db_xref="CDD:185673"
     misc_feature    complement(order(152830..152835,152854..152859,
                     152923..152925,152932..152937,152941..152946,
                     152986..152991,153205..153207,153268..153270,
                     153277..153279,153286..153288,153298..153306))
                     /gene="panC"
                     /locus_tag="ECs_0137"
                     /note="ATP-binding site [chemical binding]; other site"
                     /db_xref="CDD:185673"
     misc_feature    complement(order(152923..152925,152977..152979,
                     152986..152991,153205..153207,153214..153216,
                     153298..153300,153304..153306))
                     /gene="panC"
                     /locus_tag="ECs_0137"
                     /note="pantoate-binding site [active]"
                     /db_xref="CDD:185673"
     misc_feature    complement(153277..153288)
                     /gene="panC"
                     /locus_tag="ECs_0137"
                     /note="HXXH motif; other site"
                     /db_xref="CDD:185673"
     gene            complement(153399..154193)
                     /gene="panB"
                     /locus_tag="ECs_0138"
                     /db_xref="GeneID:913736"
     CDS             complement(153399..154193)
                     /gene="panB"
                     /locus_tag="ECs_0138"
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="NP_308165.1"
                     /db_xref="GeneID:913736"
                     /translation="MKPTTIASLQKCKQEKKRFATITAYDYSFAKLFAEEGLNVMLVG
                     DSLGMTVQGHESTLPVTVEDIAYHTTAVRRGAPNCLLLADLPFMAYATPEQAFENAAT
                     VMRAGANMVKIEGGEWLVETVKMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAS
                     DRLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDA
                     FGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH"
     misc_feature    complement(153402..154187)
                     /gene="panB"
                     /locus_tag="ECs_0138"
                     /note="3-methyl-2-oxobutanoate hydroxymethyltransferase;
                     Reviewed; Region: panB; PRK00311"
                     /db_xref="CDD:234723"
     gene            complement(154328..155437)
                     /gene="yadC"
                     /locus_tag="ECs_0139"
                     /db_xref="GeneID:913739"
     CDS             complement(154328..155437)
                     /gene="yadC"
                     /locus_tag="ECs_0139"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="NP_308166.1"
                     /db_xref="GeneID:913739"
                     /translation="MQRKGNKLLIQLCSVILLFFTTSWYALANECYIERNAEGDYHMK
                     ISSTQLSLASQMVEVPTEIAEATWDVNIQLRGDAIGCKSLGDSKAVHFLNTADPSLIS
                     TYTTTNGAALLKTTVPGIVYSVELLCLSCGAADELDLWLPAQSGADNFIPSTQTKWAY
                     EYSDQSWYLRFRLFITPEFKPKNGVSSGTTIAGKIASWYIGTNDQPWINFYIDNDSLK
                     FFVDEPTCATVALAQDQGNVSGNQVTLGNSYVSEVKNGLTREIPFSIRAEYCYASKIT
                     VKLKAANKPSDATLVGKTTGSASGVAVKVNSTYDNSKVLLKADGSNTVDYNFAAWSNN
                     LLFLPFTAQLVPDGSGNAVGVGTFSGNATFSFTYE"
     misc_feature    complement(154331..>155152)
                     /gene="yadC"
                     /locus_tag="ECs_0139"
                     /note="Fimbrial protein; Region: Fimbrial; cl01416"
                     /db_xref="CDD:412890"
     gene            complement(155449..156039)
                     /gene="yadK"
                     /locus_tag="ECs_0140"
                     /db_xref="GeneID:913740"
     CDS             complement(155449..156039)
                     /gene="yadK"
                     /locus_tag="ECs_0140"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="NP_308167.1"
                     /db_xref="GeneID:913740"
                     /translation="MLCRHHKIVHFLGLATALITPFAYSGQDVDLTAKIVPSTCQVEV
                     SNNGVVDLGTVTLDYFADNVTPTTDYAGGKTFNVNVVSCDNIQTTQSQMKLDFQPQAG
                     SLAQANNQIFSNEYEQQATGAKNVGIVIFSAQPNQQTFNVRGTDGSSTAIYSVAPGNA
                     VPSTWTFYSRMQRVNNALPPESGMVRSQVIVNVSYE"
     misc_feature    complement(155452..156039)
                     /gene="yadK"
                     /locus_tag="ECs_0140"
                     /note="putative fimbrial protein StaF; Provisional;
                     Region: PRK15262"
                     /db_xref="CDD:237933"
     gene            complement(156060..156665)
                     /gene="yadL"
                     /locus_tag="ECs_0141"
                     /db_xref="GeneID:913742"
     CDS             complement(156060..156665)
                     /gene="yadL"
                     /locus_tag="ECs_0141"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="NP_308168.1"
                     /db_xref="GeneID:913742"
                     /translation="MKLKVIATLIATVAVGVSFNSNFASASTTSASLTVNSNLTMGTC
                     SAQIMDNSNKVINEVVFGNVYISELGAKSKVQQFKIRFSNCSGLPQNSAQIVLAPNGI
                     SCAGSQSSSAGFSNKFTDASAATRTAVEVWTTDTPESNGSTQFHCAQKIPVPVTLPAD
                     TTTQPYDYPLSARMTVAEGRLVTDVRPGNFRSPTTFTITYQ"
     misc_feature    complement(156063..156653)
                     /gene="yadL"
                     /locus_tag="ECs_0141"
                     /note="fimbrial-like protein; Region: PRK15263"
                     /db_xref="CDD:185171"
     gene            complement(156680..157228)
                     /gene="yadM"
                     /locus_tag="ECs_0142"
                     /db_xref="GeneID:913744"
     CDS             complement(156680..157228)
                     /gene="yadM"
                     /locus_tag="ECs_0142"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="NP_308169.2"
                     /db_xref="GeneID:913744"
                     /translation="MKRILLTSALIGLGLPAVGSATDLNVDFTATVLATTCTITIVED
                     GGPAVTGSNDEYSLTIPDVGLDKVATAAPEAQANFKLKASDCSNGYSKIFTTLTGTTV
                     SGKLIVNEATSGAAGVGMGIKRRDTADSTFFTPNNTDKFEWSADEKASGVPLTVALRE
                     TTAGAGRTGAFQAKATFNFTYE"
     misc_feature    complement(156683..157216)
                     /gene="yadM"
                     /locus_tag="ECs_0142"
                     /note="Fimbrial protein; Region: Fimbrial; cl01416"
                     /db_xref="CDD:445401"
     gene            complement(157242..159842)
                     /gene="htrE"
                     /locus_tag="ECs_0143"
                     /db_xref="GeneID:913748"
     CDS             complement(157242..159842)
                     /gene="htrE"
                     /locus_tag="ECs_0143"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane usher protein"
                     /protein_id="NP_308170.1"
                     /db_xref="GeneID:913748"
                     /translation="MYQFTHQKSRIPKKTLLAACCALFYSSNGAAADTVEYDSSFLMG
                     TGASTIDVKRYAQGNPTPPGLYNVRVFVNGQATSSLEIPFVDIGENSAAACLTHKNLA
                     QLHIKQPEQPVTLLAREGEEEDCLDLAKSYEKADVCFDGSDQFLDLTIPQAYVLKSYG
                     GYVDPSLWESGINAATLAYTLNAYHTSSDNDNSDSVYGAFNSGINLGAWHFRARGNYN
                     WTTDNGSDFDFQDRYLQRDIPAIRSQIIMGDAYTTGETFDSVNVRGVRLYSDSRMLPS
                     ALASYAPTIRGVANSNAKVTVTQSGYKIYETTVPPGEFVIDDISPSGFGSELVVTIEE
                     ADGSKRTFTQPFSSVVQMQRPGVGRWDFSAGKVIDDSLRSEPNMGQASYYYGLNNLFT
                     GYTGIQFTDNNYLAGLLGVGINTSIGAFAVDVTHSRAEIPDDKTYQGQSYRVTWNKLF
                     QDTGTSFNLAAYRYSTQDYLGLHDALVLIDDAKHLSADEDKNTMQTYSRMKNQFTVSI
                     NQPLNIAYEDYGSLFISGSWTYYWAANNSRTEYNVGYSKSVSWGSFSVNLQRSWNEDG
                     EKDDAMYVSVSVPIENILGGKRKSSGFRNLNTQLNTDFDGSHQLNVNSSGNTENNLVN
                     YSVNAGYSLDKNAGDLASVGGYLNYESGLGGISASASATSDNSQQYSISTDGGFVLHS
                     GGLTFTNNSFSSNDTLVLINALGAKGARINNSNNEIDRWGYAVTSSVSPYRENRVGLN
                     IETLENDVELKSTSATTVPRSGSVVLTRFETDEGRSAVLNITAANGKSIPFAAEVYQG
                     EVMIGSMGQGGQAFVRGINDSGELIVRWYENNQTIDCKLHYQFPAQPQTQGSTNTLLL
                     NNLTCQVANH"
     misc_feature    complement(157296..159839)
                     /gene="htrE"
                     /locus_tag="ECs_0143"
                     /note="putative fimbrial outer membrane usher protein;
                     Provisional; Region: PRK09828"
                     /db_xref="CDD:182098"
     gene            complement(159884..160609)
                     /gene="yadV"
                     /locus_tag="ECs_0144"
                     /db_xref="GeneID:913756"
     CDS             complement(159884..160609)
                     /gene="yadV"
                     /locus_tag="ECs_0144"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic pilin chaperone"
                     /protein_id="NP_308171.1"
                     /db_xref="GeneID:913756"
                     /translation="MFPLVKKTVSALFVSTLLASAPAFADIIISGTRIIYNADKKDVN
                     VRLENKGNRPLLIQNWLDTGDDNADPSQIKVPFTATPPVSRVEPKRGQTVKVMYTGAT
                     ALPKDRESVYWFNVLEVPPKPKDAEADKNLLQLAFRTRIKLFYRPSGLQGEPAEAPAK
                     ITWKLNNAQLQANNPTPYYVSFNEVKLESGGKTYNVNSSMVTPFSQASFGVTSLPGSV
                     SSGKVVFKAINDFGGNIDGSATF"
     misc_feature    complement(159887..160609)
                     /gene="yadV"
                     /locus_tag="ECs_0144"
                     /note="fimbrial chaperone; Region: PRK09926"
                     /db_xref="CDD:236634"
     gene            complement(160696..161292)
                     /gene="yadN"
                     /locus_tag="ECs_0145"
                     /db_xref="GeneID:913761"
     CDS             complement(160696..161292)
                     /gene="yadN"
                     /locus_tag="ECs_0145"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="NP_308172.1"
                     /db_xref="GeneID:913761"
                     /translation="MKKALLAAALVMASGSALAVDGGHIDFNGMVQSGTCKVGVVDTG
                     MHSVTTDGVVTLDTANVTDTFAEVSATAVGLLPKEFMISVECDPGAPKNAELTMGSAS
                     YANTSGTLNNNMNITVNGIAPAQNVNIAVHNMKNKAGAAEIKQVHMNNSSEVQELTLD
                     AEGKGQYVFNASYVKAPNSPAVTAGHVTTNALYTVAYK"
     misc_feature    complement(160699..161292)
                     /gene="yadN"
                     /locus_tag="ECs_0145"
                     /note="Fimbrial protein; Region: Fimbrial; cl01416"
                     /db_xref="CDD:445401"
     gene            complement(161573..162055)
                     /gene="folK"
                     /locus_tag="ECs_0146"
                     /db_xref="GeneID:913762"
     CDS             complement(161573..162055)
                     /gene="folK"
                     /locus_tag="ECs_0146"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-hydroxymethyldihyropteridine
                     pyrophosphokinase"
                     /protein_id="NP_308173.1"
                     /db_xref="GeneID:913762"
                     /translation="MTVAYIAIGSNLASPLEQVNAALKALGDIPESHILTVSSFYRTP
                     PLGPQDQPDYLNAAVALETTLAPEELLNHTQQIELQQGRVRKAERWGPRTLDLDIMLF
                     GNETINTERLTVPHYDMKNRGFMLWPLFEIAPELVFPDGETLREILTSLAVLQPAIWY
                     "
     misc_feature    complement(161579..162055)
                     /gene="folK"
                     /locus_tag="ECs_0146"
                     /note="2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase; Region: PRK10239"
                     /db_xref="CDD:182325"
     misc_feature    complement(order(161684..161686,161690..161692,
                     161705..161710,161717..161719,161759..161764,
                     161768..161770,161777..161779,161786..161788,
                     161801..161803,161807..161809,161822..161824,
                     161831..161833,161843..161845,161888..161890,
                     161894..161896,161918..161920,161924..161929,
                     162029..162031))
                     /gene="folK"
                     /locus_tag="ECs_0146"
                     /note="catalytic center binding site [active]"
                     /db_xref="CDD:238269"
     misc_feature    complement(order(161690..161692,161705..161710,
                     161717..161719,161759..161764,161777..161779,
                     161801..161803,161807..161809,161822..161824,
                     161831..161833,161843..161845))
                     /gene="folK"
                     /locus_tag="ECs_0146"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238269"
     gene            complement(162052..163449)
                     /gene="pcnB"
                     /locus_tag="ECs_0147"
                     /db_xref="GeneID:913763"
     CDS             complement(162052..163449)
                     /gene="pcnB"
                     /locus_tag="ECs_0147"
                     /note="ATT start"
                     /codon_start=1
                     /transl_table=11
                     /product="poly(A) polymerase"
                     /protein_id="NP_308174.3"
                     /db_xref="GeneID:913763"
                     /translation="MFTRVANFCRKVLSREESEAEQAVARPQVTVIPREQHAISRKDI
                     SENALKVMYRLNKAGYEAWLVGGGVRDLLLGKKPKDFDVTTNATPEQVRKLFRNCRLV
                     GRRFRLAHVMFGPEIIEVATFRGHHEGNVSDRTTSQRGQNGMLLRDNIFGSIEEDAQR
                     RDFTINSLYYSVADFTVRDYVGGMKDLKDGVIRLIGNPETRYREDPVRMLRAVRFAAK
                     LGMRISPETAEPIPRLATLLNDIPPARLFEESLKLLQAGYGYETYKLLCEYHLFQPLF
                     PTITRYFTENGDSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAAMFWYPLLETAQKIA
                     QESGLTYHDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQGKRAWKLL
                     EHPKFRAAYDLLALRAEVERNAELQRLVKWWGEFQVSAPPDQKGMLNELDEEPSPRRR
                     TRRPRKRAPRREGTA"
     misc_feature    complement(162118..163449)
                     /gene="pcnB"
                     /locus_tag="ECs_0147"
                     /note="poly(A) polymerase I; Provisional; Region: pcnB;
                     PRK11623"
                     /db_xref="CDD:236939"
     gene            complement(163509..164435)
                     /gene="gluQ"
                     /locus_tag="ECs_0148"
                     /db_xref="GeneID:913766"
     CDS             complement(163509..164435)
                     /gene="gluQ"
                     /locus_tag="ECs_0148"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-Q tRNA(Asp) synthetase"
                     /protein_id="NP_308175.3"
                     /db_xref="GeneID:913766"
                     /translation="MLPPYFLFKEMTDTQYIGRFAPSPSGELHFGSLIAALGSYLQAR
                     ARHGRWLVRIEDIDPPREVPGAAETILRQLEHYGLHWDGDVLWQSQRHHAYREALAWL
                     HEQGLSYYCTCTRARIQSIGGIYDGHCRVLHHGPDNAAVRIRQQHPVTQFTDQLRGII
                     HADEKLAREDFIIHRRDGLFAYNLAVVVDDHFQGVSEIVRGADLIEPTVRQISLYQLF
                     GWKVPDYIHLPLALNPQGAKLSKQNHAPALPKGDPRPVLIAALQFLGQQAEAHWQDFS
                     VEQILQSAVKNWRLTAVPESAIVNSTFSNASC"
     misc_feature    complement(163527..164405)
                     /gene="gluQ"
                     /locus_tag="ECs_0148"
                     /note="tRNA glutamyl-Q(34) synthetase GluQRS; Region:
                     PRK05710"
                     /db_xref="CDD:235573"
     misc_feature    complement(order(163713..163715,164340..164342,
                     164349..164351))
                     /gene="gluQ"
                     /locus_tag="ECs_0148"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:173912"
     misc_feature    complement(164340..164351)
                     /gene="gluQ"
                     /locus_tag="ECs_0148"
                     /note="HIGH motif; other site"
                     /db_xref="CDD:173912"
     gene            complement(164472..164927)
                     /gene="dksA"
                     /locus_tag="ECs_0149"
                     /db_xref="GeneID:913772"
     CDS             complement(164472..164927)
                     /gene="dksA"
                     /locus_tag="ECs_0149"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_308176.1"
                     /db_xref="GeneID:913772"
                     /translation="MQEGQNRKTSSLSILAIAGVEPYQEKPGEEYMNEAQLAHFRRIL
                     EAWRNQLRDEVDRTVTHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKT
                     LKKVEDEDFGYCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG"
     misc_feature    complement(164475..164927)
                     /gene="dksA"
                     /locus_tag="ECs_0149"
                     /note="RNA polymerase-binding protein DksA; Region: dksA;
                     PRK10778"
                     /db_xref="CDD:182722"
     gene            complement(165105..165809)
                     /gene="sfsA"
                     /locus_tag="ECs_0150"
                     /db_xref="GeneID:913774"
     CDS             complement(165105..165809)
                     /gene="sfsA"
                     /locus_tag="ECs_0150"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar fermentation stimulation protein A"
                     /protein_id="NP_308177.1"
                     /db_xref="GeneID:913774"
                     /translation="MEFSPPLQRATLIQRYKRFLADVITPDGRELTLHCPNTGAMTGC
                     ATPGDTVWYSTSDNTKRKYPHTWELTQSQSGAFICVNTLWANRLTKEAILNESISELS
                     GYSSLKSEVKYGAERSRIDFMLQADSRPDCYIEVKSVTLAENEQGYFPDAVTERGQKH
                     LRELMSVAAEGQRAVIFFAVLHSAITRFSPARHIDEKYAQLLSEAQQRGVEILAYKAE
                     ISAEGMALKKSLPVTL"
     misc_feature    complement(165108..165809)
                     /gene="sfsA"
                     /locus_tag="ECs_0150"
                     /note="sugar fermentation stimulation protein; Region:
                     sfsA; TIGR00230"
                     /db_xref="CDD:272972"
     gene            complement(165824..166354)
                     /gene="ligT"
                     /locus_tag="ECs_0151"
                     /db_xref="GeneID:913775"
     CDS             complement(165824..166354)
                     /gene="ligT"
                     /locus_tag="ECs_0151"
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase"
                     /protein_id="NP_308178.2"
                     /db_xref="GeneID:913775"
                     /translation="MSDPQRLFFAIDLPAEIREQIIHWRATHFPLEAGRPVAADNLHL
                     TLAFLGEVSAEKEKALSLLAGRIRQPGFTLTLDDAGQWLRSRVVWLGMRQPPRGLIQL
                     ANMLRSQAARSGCFQSNRPFHPHITLLRDASEAVTIPPPGFNWSYAVTEFTLYASSFA
                     RGRTRYTPLKRWVLTQ"
     misc_feature    complement(165827..166354)
                     /gene="ligT"
                     /locus_tag="ECs_0151"
                     /note="RNA 2',3'-cyclic phosphodiesterase; Region:
                     PRK15124"
                     /db_xref="CDD:185079"
     gene            166428..168857
                     /gene="hrpB"
                     /locus_tag="ECs_0152"
                     /db_xref="GeneID:913779"
     CDS             166428..168857
                     /gene="hrpB"
                     /locus_tag="ECs_0152"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="NP_308179.2"
                     /db_xref="GeneID:913779"
                     /translation="MSSLPVAAVLPELLTALDYAPQVLLSAPTGAGKSTWLPLQLLAH
                     PGINGKIILLEPRRLAARNVAQRLAELLNEKPGDTVGYRMRAQNCVGPNTRLEVVTEG
                     VLTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVQQGLRDDLKLLIMSATLD
                     NDRLQQMLPEAPVVISEGRSFPVERRYLPLPTHQRFDDAVAVATAEMLRQESGSLLLF
                     LPGVGEIQRVQEQLASRIGSDVLLCPLYGALSLNDQRKAILPAPQGMRKVVLATNIAE
                     TSLTIEGIRLVVDCAQERVARFDPRTGLTRLITQRISQASMTQRAGRAGRLEPGICLH
                     LIAKEQAERATAQSEPEILQSDLSGLLMELLQWGCSDPAQMSWLDQPPTVNLLAAKRL
                     LQMLGALDGERLSAQGQKMAALGNDPRLAAMLVSAKSDDEAATAAKIAAILEEPPRMG
                     NSDLGVAFSRNQPAWQQRSQQLLKRLNVRGGEADSSLIAPLLAGAFADRIARRRGQDG
                     RYQLANGMGAMLDADDALSRHEWLIAPLLLQGSASPDARILLALPVDIDELVQRCPQL
                     VQQSDTVEWDDAQGTLKAWRRLQIGQLTVKVQPLAKPSEDELHQAMLNGIRDKGLSVL
                     NWTAEAEQLRLRLLCAGKWLPEYDWPAVDDESLLATLETWLLPHMAGVHSLRGLKSLD
                     IYQALRGLLDWGMQQRLDSELPAHYTVPTGSRIAIRYHEDNPPALAVRMQEMFGEATN
                     PTIAQGRVPLVLELLSPAQRPLQITRDLGAFWKGAYREVQKEMKGRYPKHVWPDDPAN
                     TAPTRRTKKYS"
     misc_feature    166428..168854
                     /gene="hrpB"
                     /locus_tag="ECs_0152"
                     /note="ATP-dependent RNA helicase HrpB; Provisional;
                     Region: PRK11664"
                     /db_xref="CDD:236950"
     gene            169053..171587
                     /gene="mrcB"
                     /locus_tag="ECs_0153"
                     /db_xref="GeneID:913781"
     CDS             169053..171587
                     /gene="mrcB"
                     /locus_tag="ECs_0153"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1B"
                     /protein_id="NP_308180.1"
                     /db_xref="GeneID:913781"
                     /translation="MAGNDREPIGRKGKPTRPVKQKVSRRRYEDDDDYDDYDDYEDEE
                     PMPRKGKGKGKGRKPRGKRGWLWLLLKLAIVFAVLIAIYGVYLDQKIRSRIDGKVWQL
                     PAAVYGRMVNLEPDMTISKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFD
                     FPDSKEGQVRARLTFDGDHLATIVNMENNRQFGFFRLDPRLITMISSPNGEQRLFVPR
                     SGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGASTLTQQLVKNL
                     FLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRGFPLASLYY
                     FGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQQIIDQELYD
                     MLSARPLGVQPRGGVISPQPAFMQLVRQELQAKLGDKVKDLSGVKIFTTFDSVAQDAA
                     EKAAVEGIPALKKQRKLSDLETAIVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSI
                     GSLAKPATYLTALSQPKIYRLNTWIADAPIALRQPNGQVWSPQNDDRRYSESGRVMLV
                     DALTRSMNVPTVNLGMALGLPAVTDTWIKLGVPKDQLHPVPAMLLGALNLTPIEVAQA
                     FQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLWTMQQVVQRGT
                     GRQLGAKYPNLHLAGKTGTTNNNVDTWFAGIDGSTVTITWVGRDNNQPTKLYGASGAM
                     SIYQRYLANQTPTPLNLVPPEDIADMGVDYDGNFVCSGGMRVLPVWTSDPQSLCQQSE
                     MQQQPSGNPFDQSSQPQQQPQQQPAQQEQKDSDGVAGWIKDMFGSN"
     misc_feature    169053..171581
                     /gene="mrcB"
                     /locus_tag="ECs_0153"
                     /note="bifunctional glycosyl transferase/transpeptidase;
                     Reviewed; Region: mrcB; PRK09506"
                     /db_xref="CDD:236544"
     gene            171807..174050
                     /gene="fhuA"
                     /locus_tag="ECs_0154"
                     /db_xref="GeneID:913783"
     CDS             171807..174050
                     /gene="fhuA"
                     /locus_tag="ECs_0154"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrichrome outer membrane transporter"
                     /protein_id="NP_308181.1"
                     /db_xref="GeneID:913783"
                     /translation="MARSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVELKEDTITV
                     TAAPAPQESAWGPAATIAARQSATGTKTDTPIQKVPQSISVVTAEEMALHQPKSVKEA
                     LSYTPGVSVGTRGASNTYDHLIIRGFAAEGQSQNNYLNGLKLQGNFYNDAVIDPYMLE
                     RAEIMRGPVSVLYGKSSPGGLLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDALD
                     DDGVYSYRLTGLARSANAQQKGSEEQRYAIAPAFTWRPDDKTNFTFLSYFQNEPETGY
                     YGWLPKEGTVEPLPNGKRLPTDFNEGAKNNTYSRNEKMVGYSFDHEFNDTFTVRQNLR
                     FAENKTSQNSVYGYGVCSDPANAYSKQCAALAPADKGHYLARKYVVDDEKLQNFSVDT
                     QLQSKFATGDIDHTLLTGVDFMRMRNDINAWFGYDDSVPLLDLYNPVNTDFDFNAKDP
                     ANSGPYRILNKQKQTGVYVQDQAQWDKVLVTLGGRYDWADQESLNRVAGTTDKRDDKQ
                     FTWRGGVNYLFDNGVTPYFSYSESFEPSSQVGKDGNIFAPSKGKQYEVGVKYVPEDRP
                     IVVTGAVYNLTKTNNLMADPEGSFFSVEGGEIRARGVEIEAKAALSASVNVVGSYTYT
                     DAEYTTDTTYKGNTPAQVPKHMASLWADYTFFDGPLSGLTLGTGGRYTGSSYGDPANS
                     FKVGSYTVVDALVRYDLARVGMAGSNVALHVNNLFDREYVASCFNTYGCFWGAERQVV
                     ATATFRF"
     misc_feature    171807..174047
                     /gene="fhuA"
                     /locus_tag="ECs_0154"
                     /note="ferrichrome outer membrane transporter;
                     Provisional; Region: PRK10044"
                     /db_xref="CDD:236643"
     gene            174101..174898
                     /gene="fhuC"
                     /locus_tag="ECs_0155"
                     /db_xref="GeneID:913784"
     CDS             174101..174898
                     /gene="fhuC"
                     /locus_tag="ECs_0155"
                     /codon_start=1
                     /transl_table=11
                     /product="iron(3+)-hydroxamate import ABC transporter
                     ATPase"
                     /protein_id="NP_308182.1"
                     /db_xref="GeneID:913784"
                     /translation="MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIG
                     HNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPPAEGMTV
                     RELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAM
                     LVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYL
                     VALRGGEMIAQGTPAEIMRGETLEMIYGIPMGILPHPAGAAPVSFVY"
     misc_feature    174101..174895
                     /gene="fhuC"
                     /locus_tag="ECs_0155"
                     /note="Fe3+-hydroxamate ABC transporter ATP-binding
                     protein FhuC; Region: PRK10575"
                     /db_xref="CDD:182561"
     gene            174898..175788
                     /gene="fhuD"
                     /locus_tag="ECs_0156"
                     /db_xref="GeneID:913786"
     CDS             174898..175788
                     /gene="fhuD"
                     /locus_tag="ECs_0156"
                     /codon_start=1
                     /transl_table=11
                     /product="iron(3+)-hydroxamate import ABC transporter
                     periplasmic binding protein"
                     /protein_id="NP_308183.1"
                     /db_xref="GeneID:913786"
                     /translation="MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWL
                     PVELLLALGIVPYGVADTINYRLWVSEPPLPESVIDVGLRTEPNLELLTEMKPSFMVW
                     SAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYED
                     FIRSMNPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWG
                     STAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYG
                     ATLSAMHFVRVLDNAIGGKA"
     misc_feature    174907..175782
                     /gene="fhuD"
                     /locus_tag="ECs_0156"
                     /note="Fe(3+)-hydroxamate ABC transporter
                     substrate-binding protein FhuD; Region: PRK10576"
                     /db_xref="CDD:236719"
     misc_feature    order(175099..175101,175147..175152,175213..175215,
                     175462..175464)
                     /gene="fhuD"
                     /locus_tag="ECs_0156"
                     /note="siderophore binding site [active]"
                     /db_xref="CDD:238566"
     gene            175785..177767
                     /gene="fhuB"
                     /locus_tag="ECs_0157"
                     /db_xref="GeneID:913787"
     CDS             175785..177767
                     /gene="fhuB"
                     /locus_tag="ECs_0157"
                     /codon_start=1
                     /transl_table=11
                     /product="iron(3+)-hydroxamate import ABC transporter
                     permease"
                     /protein_id="NP_308184.1"
                     /db_xref="GeneID:913787"
                     /translation="MSKRIALFPALLLALLVIAATALTWMNFSQALPRSQWAQAAWSP
                     DIDVIEQMIFHYSLLPRLAISLLVGAGLGLVGVLFQQVLRNPLAEPTTLGVATGAQLG
                     ITVTTLWAIPGAMASQFAALAGACVVGLIVFGVAWGKRLSPVTLILAGLVVSLYCGAI
                     NQLLVIFHHDQLQSMFLWSTGTLTQTDWGGVERLWPQLLGGVMLTLLLLRPLTLMGLD
                     DGVARNLGLALSLARLAALSLAIVISALLVNAVGIIGFIGLFAPLLAKMLGARRLLPR
                     LMLASLIGALILWLSDQIILWLTRVWMEVSTGSVTALIGAPLLLWLLPRLRSISAPDM
                     KVNDRVAAERQHVLAFALAGGVLLLMAVVVALSFGRDAHGWTWASGALLEDLMPWRWP
                     RIMAALFAGVMLAVAGCIIQRLTGNPMASPEVLGISSGAAFGVVLMLFLVPGNAFGWL
                     LPAGSIGAAVTLLIIMIAAGRGGFSPHRMLLAGMALSTAFTMLLMMLQASGDPRMAQV
                     LTWISGSTYNATDAQVWRTGIVMVILLAITPLCRRWLTILPLGGDTARAVGVALTPTR
                     IALLLLAACLTATATMTIGPLSFVGLMAPHIARMMGFRRTMPHIVISALVGGLLLVFA
                     DWCGRMVLFPFQIPAGLLSTFIGAPYFIYLLRKQSR"
     misc_feature    175785..177764
                     /gene="fhuB"
                     /locus_tag="ECs_0157"
                     /note="Fe(3+)-hydroxamate ABC transporter permease FhuB;
                     Region: PRK10577"
                     /db_xref="CDD:236720"
     misc_feature    order(177018..177020,177030..177038,177399..177404,
                     177408..177416,177420..177425,177429..177446,
                     177450..177458,177579..177581,177600..177602)
                     /gene="fhuB"
                     /locus_tag="ECs_0157"
                     /note="ABC-ATPase subunit interface [active]"
                     /db_xref="CDD:119348"
     misc_feature    order(177033..177035,177039..177041,177054..177056,
                     177216..177218,177222..177227,177234..177239,
                     177246..177251,177258..177260,177267..177272,
                     177276..177278,177309..177314,177321..177323,
                     177549..177551,177705..177707,177714..177719,
                     177726..177728,177735..177740,177747..177749)
                     /gene="fhuB"
                     /locus_tag="ECs_0157"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119348"
     misc_feature    order(177276..177278,177351..177353,177525..177527,
                     177537..177539,177669..177671,177696..177698)
                     /gene="fhuB"
                     /locus_tag="ECs_0157"
                     /note="putative PBP binding regions [active]"
                     /db_xref="CDD:119348"
     gene            complement(177802..179082)
                     /gene="hemL"
                     /locus_tag="ECs_0158"
                     /db_xref="GeneID:913788"
     CDS             complement(177802..179082)
                     /gene="hemL"
                     /locus_tag="ECs_0158"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="NP_308185.1"
                     /db_xref="GeneID:913788"
                     /translation="MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYL
                     YDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVTEL
                     VPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTL
                     GQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPD
                     FLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVEPDLTCLGKIIGGGMPVGAF
                     GGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGVHETLDELTTRLAEG
                     LLEAAEEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVY
                     LAPSAFEAGFMSVAHSMEDINNTIDAARRVFAKL"
     misc_feature    complement(177805..179082)
                     /gene="hemL"
                     /locus_tag="ECs_0158"
                     /note="glutamate-1-semialdehyde 2,1-aminomutase; Region:
                     PRK00062"
                     /db_xref="CDD:234607"
     misc_feature    complement(order(178288..178290,178363..178368,
                     178372..178374,178471..178473,178648..178650,
                     178654..178659,178735..178743))
                     /gene="hemL"
                     /locus_tag="ECs_0158"
                     /note="inhibitor-cofactor binding pocket [active]"
                     /db_xref="CDD:99735"
     misc_feature    complement(order(178288..178290,178363..178365,
                     178372..178374,178471..178473,178654..178659,
                     178735..178740))
                     /gene="hemL"
                     /locus_tag="ECs_0158"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99735"
     misc_feature    complement(178288..178290)
                     /gene="hemL"
                     /locus_tag="ECs_0158"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99735"
     gene            179307..180728
                     /gene="clcA"
                     /locus_tag="ECs_0159"
                     /db_xref="GeneID:913789"
     CDS             179307..180728
                     /gene="clcA"
                     /locus_tag="ECs_0159"
                     /codon_start=1
                     /transl_table=11
                     /product="H(+)/Cl(-) exchange transporter"
                     /protein_id="NP_308186.1"
                     /db_xref="GeneID:913789"
                     /translation="MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGT
                     LVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAP
                     EAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGR
                     MVLDVFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAV
                     FIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGM
                     QDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLV
                     FIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIA
                     GMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILA
                     RTLAKQEAEQLARSKAASASENT"
     misc_feature    179412..180725
                     /gene="clcA"
                     /locus_tag="ECs_0159"
                     /note="H(+)/Cl(-) exchange transporter ClcA; Region:
                     PRK05277"
                     /db_xref="CDD:235385"
     misc_feature    order(179622..179636,179742..179756,180369..180383,
                     180639..180641)
                     /gene="clcA"
                     /locus_tag="ECs_0159"
                     /note="Cl- selectivity filter [active]"
                     /db_xref="CDD:238504"
     misc_feature    order(179625..179627,179631..179633,179748..179753,
                     180369..180377,180639..180641)
                     /gene="clcA"
                     /locus_tag="ECs_0159"
                     /note="Cl- binding residues [ion binding]; other site"
                     /db_xref="CDD:238504"
     misc_feature    179748..179750
                     /gene="clcA"
                     /locus_tag="ECs_0159"
                     /note="pore gating glutamate residue [active]"
                     /db_xref="CDD:238504"
     misc_feature    order(179886..179888,179913..179915,179952..179954,
                     179973..179975,180513..180515,180522..180524,
                     180546..180548,180582..180584,180603..180608,
                     180615..180617)
                     /gene="clcA"
                     /locus_tag="ECs_0159"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238504"
     misc_feature    179913..179915
                     /gene="clcA"
                     /locus_tag="ECs_0159"
                     /note="H+/Cl- coupling transport residue [active]"
                     /db_xref="CDD:238504"
     gene            180810..181154
                     /gene="erpA"
                     /locus_tag="ECs_0160"
                     /db_xref="GeneID:913801"
     CDS             180810..181154
                     /gene="erpA"
                     /locus_tag="ECs_0160"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster insertion protein"
                     /protein_id="NP_308187.1"
                     /db_xref="GeneID:913801"
                     /translation="MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSG
                     FQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNA
                     KSTCGCGSSFSI"
     misc_feature    180810..181151
                     /gene="erpA"
                     /locus_tag="ECs_0160"
                     /note="iron-sulfur cluster insertion protein ErpA;
                     Provisional; Region: PRK13623"
                     /db_xref="CDD:184186"
     gene            complement(181201..181824)
                     /gene="yadS"
                     /locus_tag="ECs_0161"
                     /db_xref="GeneID:913809"
     CDS             complement(181201..181824)
                     /gene="yadS"
                     /locus_tag="ECs_0161"
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein"
                     /protein_id="NP_308188.1"
                     /db_xref="GeneID:913809"
                     /translation="MLVYWLDIVGTAVFAISGVLLAGKLRMDPFGVLVLGVVTAVGGG
                     TIRDMALDHGPVFWVKDPTDLVVAMVTSMLTIVLVRQPRHLPKWMLPVLDAVGLAVFV
                     GIGVNKAFNAEAGPLIAVCMGVITGVGGGIIRDVLAREIPMILRTEIYATACIIGGIV
                     HATAYYTFSVPLETASMMGMVVTLLIRLAAIRWHLKLPTFALDENGR"
     misc_feature    complement(181204..181824)
                     /gene="yadS"
                     /locus_tag="ECs_0161"
                     /note="hypothetical protein; Provisional; Region:
                     PRK10578"
                     /db_xref="CDD:182564"
     gene            complement(181862..182662)
                     /gene="btuF"
                     /locus_tag="ECs_0162"
                     /db_xref="GeneID:913812"
     CDS             complement(181862..182662)
                     /gene="btuF"
                     /locus_tag="ECs_0162"
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter periplasmic binding
                     protein"
                     /protein_id="NP_308189.1"
                     /db_xref="GeneID:913812"
                     /translation="MAKSLFRALVALSFLAPLWLNAAPRVITLSPANTELAFAAGITP
                     VGVSSYSDYPPQAQKIEQVSTWQGMNLERIVALKPDLVIAWRGGNAERQVDQLASLGI
                     KVMWVDATNIEQIANALRQLAPWSPQPDKAEQAAQSLLDQYAQLKAQYADKPKKRVFL
                     QFGINPPFTSGKESIQNQVLEVCGGENIFKDSRVPWPQVSREQVLARSPQAIVITGGP
                     DQIPKIKQYWGEQLKIPVIPLTSDWFERASPRIILAAQQLCNALSQVD"
     misc_feature    complement(181865..182644)
                     /gene="btuF"
                     /locus_tag="ECs_0162"
                     /note="vitamin B12-transporter protein BtuF; Provisional;
                     Region: PRK03379"
                     /db_xref="CDD:179575"
     misc_feature    complement(order(182075..182077,182159..182161,
                     182402..182404,182408..182410,182513..182515,
                     182567..182572))
                     /gene="btuF"
                     /locus_tag="ECs_0162"
                     /note="cobalamin binding residues [chemical binding];
                     other site"
                     /db_xref="CDD:238564"
     misc_feature    complement(order(182057..182059,182447..182449))
                     /gene="btuF"
                     /locus_tag="ECs_0162"
                     /note="putative BtuC binding residues [active]"
                     /db_xref="CDD:238564"
     misc_feature    complement(order(182300..182305,182312..182314,
                     182321..182326,182330..182332,182339..182341,
                     182351..182353,182369..182371,182378..182380,
                     182405..182407))
                     /gene="btuF"
                     /locus_tag="ECs_0162"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238564"
     gene            complement(182655..183353)
                     /gene="mtn"
                     /locus_tag="ECs_0163"
                     /db_xref="GeneID:913817"
     CDS             complement(182655..183353)
                     /gene="mtn"
                     /locus_tag="ECs_0163"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine nucleosidase"
                     /protein_id="NP_308190.1"
                     /db_xref="GeneID:913817"
                     /translation="MKIGIIGAMEEEVTLLRDKIENRQTISLGGCEIYTGQLNGTEVA
                     LLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADV
                     TAFGYEYGQLPGCPAGFKADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAK
                     IRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQS
                     SLMVESLVQKLAHG"
     misc_feature    complement(182664..183353)
                     /gene="mtn"
                     /locus_tag="ECs_0163"
                     /note="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase; Region: PRK05584"
                     /db_xref="CDD:180148"
     misc_feature    complement(order(182718..182720,182757..182759,
                     182763..182768,182775..182777,182832..182843,
                     182901..182906,183120..183128,183201..183206,
                     183318..183320,183327..183332))
                     /gene="mtn"
                     /locus_tag="ECs_0163"
                     /note="active site"
                     /db_xref="CDD:350159"
     misc_feature    complement(order(182796..182807,182811..182816,
                     182823..182825,182835..182837,182901..182909,
                     183057..183059,183063..183065,183159..183167,
                     183171..183176,183183..183188,183192..183209,
                     183213..183215,183261..183263,183324..183326))
                     /gene="mtn"
                     /locus_tag="ECs_0163"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:350159"
     gene            183437..184954
                     /gene="dgt"
                     /locus_tag="ECs_0164"
                     /db_xref="GeneID:913819"
     CDS             183437..184954
                     /gene="dgt"
                     /locus_tag="ECs_0164"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyguanosine triphosphate triphosphohydrolase"
                     /protein_id="NP_308191.1"
                     /db_xref="GeneID:913819"
                     /translation="MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPA
                     IRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDEL
                     TGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAVL
                     RLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWW
                     RGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVAD
                     LEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFM
                     YLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFS
                     HPDVEQLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRSPIESRLFHKLSTR
                     HRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ"
     misc_feature    183437..184948
                     /gene="dgt"
                     /locus_tag="ECs_0164"
                     /note="deoxyguanosinetriphosphate triphosphohydrolase;
                     Provisional; Region: dgt; PRK04926"
                     /db_xref="CDD:235320"
     gene            185084..186508
                     /gene="degP"
                     /locus_tag="ECs_0165"
                     /db_xref="GeneID:913821"
     CDS             185084..186508
                     /gene="degP"
                     /locus_tag="ECs_0165"
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease"
                     /protein_id="NP_308192.1"
                     /db_xref="GeneID:913821"
                     /translation="MKKTTLALSALALSLGLALSPLSATAAETSSATTAQQMPSLAPM
                     LEKVMPSVVSINVEGSTTVNTPRMPRNFQQFFGDDSPFCQEGSPFQSSPFCQGGQGGN
                     GGGQQQKFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKDPRS
                     DIALIQIQNPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNA
                     ENYENFIQTDAAINRGNSGGALVNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNL
                     TSQMVEYGQVKRGELGIMGTELNSELAKAMKVDAQRGAFVSQVLPNSSAAKAGIKAGD
                     VITSLNGKPISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQSSQNQVDSSS
                     IFNGIEGAEMSNKGKDQGVVVNNVKTGTPAAQIGLKKGDVIIGANQQAVKNIAELRKV
                     LDSKPSVLALNIQRGDSTIYLLMQ"
     misc_feature    185087..186505
                     /gene="degP"
                     /locus_tag="ECs_0165"
                     /note="serine endoprotease DegP; Region: PRK10942"
                     /db_xref="CDD:236802"
     gene            186663..187820
                     /gene="cdaR"
                     /locus_tag="ECs_0166"
                     /db_xref="GeneID:913826"
     CDS             186663..187820
                     /gene="cdaR"
                     /locus_tag="ECs_0166"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate diacid regulator"
                     /protein_id="NP_308193.1"
                     /db_xref="GeneID:913826"
                     /translation="MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERI
                     GELHEGALLVLSQGRVVDIDDAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPENLR
                     KYGELVCMTAEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDL
                     NQPRVVAIVEVDSGQLGVDSAMAELQQLQNALTTPERNNLVAIVSLTEMVVLKPALNS
                     FGRWDVEDHRKRVEQLITRMKEYGQLRFRVSLGNYFTGPGSIARSYRTAKTTMVVGKQ
                     RMPESRCYFYQDLMLPVLLDSLRGDWQANELARPLARLKAMDNNGLLRRTLAAWFRHN
                     VQPLATSKALFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEER"
     misc_feature    186663..187817
                     /gene="cdaR"
                     /locus_tag="ECs_0166"
                     /note="CdaR family transcriptional regulator; Region:
                     PRK11477"
                     /db_xref="CDD:183155"
     gene            complement(187909..188295)
                     /gene="yaeH"
                     /locus_tag="ECs_0167"
                     /db_xref="GeneID:913827"
     CDS             complement(187909..188295)
                     /gene="yaeH"
                     /locus_tag="ECs_0167"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308194.1"
                     /db_xref="GeneID:913827"
                     /translation="MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAK
                     SVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYIIDELDQICQRDRSEVDLKRKILD
                     DLRHLESVVTNKISEIEADLEKLTRK"
     misc_feature    complement(187921..188295)
                     /gene="yaeH"
                     /locus_tag="ECs_0167"
                     /note="DUF3461 family protein; Region: PRK13677"
                     /db_xref="CDD:184234"
     gene            complement(188610..189434)
                     /gene="dapD"
                     /locus_tag="ECs_0168"
                     /db_xref="GeneID:913832"
     CDS             complement(188610..189434)
                     /gene="dapD"
                     /locus_tag="ECs_0168"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2-carboxylate
                     N-succinyltransferase"
                     /protein_id="NP_308195.1"
                     /db_xref="GeneID:913832"
                     /translation="MQQLQNIIETAFERRAEITPANADTVTREAVNQVIALLDSGALR
                     VAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAESRYFDKVPMKFADYDEARFQKEG
                     FRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
                     GVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRE
                     TGDIHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID"
     misc_feature    complement(188622..189434)
                     /gene="dapD"
                     /locus_tag="ECs_0168"
                     /note="2,3,4,5-tetrahydropyridine-2,6-carboxylate
                     N-succinyltransferase; Provisional; Region: dapD;
                     PRK11830"
                     /db_xref="CDD:236996"
     gene            complement(189465..192137)
                     /gene="glnD"
                     /locus_tag="ECs_0169"
                     /db_xref="GeneID:913839"
     CDS             complement(189465..192137)
                     /gene="glnD"
                     /locus_tag="ECs_0169"
                     /codon_start=1
                     /transl_table=11
                     /product="uridylyltransferase"
                     /protein_id="NP_308196.1"
                     /db_xref="GeneID:913839"
                     /translation="MNTLPEQYANTALPTLPGQPQNPCVWPRDELTVGGIKAHIDTFQ
                     RWLGDAFDNGISAEQLIEARTEFIDQLLQRLWIEAGFSQIADLALVAVGGYGRGELHP
                     LSDIDLLILSRKKLPDDQAQKVGELLTLLWDVKLEVGHSVRTLEECMLEGLSDLTVAT
                     NLIESRLLIGDVALFLELQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPD
                     IKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTSAERAELNECLHILWRIRFAL
                     HLVVSRYDNRLLFDRQLSVAQRLNYSGEGNEPVERMMKDYFRVTRRVSELNQMLLQLF
                     DEAILALPADEKPRPIDDEFQLRGTLIDLRDETLFMRQPEAILRMFYTMVRNSAITGI
                     YSTTLRQLRHARRHLQQPLCNIPQARKLFLSILRHPGAVRRGLLPMHRHSVLGAYMPQ
                     WSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFASEETRQRHPLCVNVWPRLPSTELIF
                     IAALFHDIAKGRGGDHSILGAQDVVHFAELHGLNSRETQLVAWLVRQHLLMSVTAQRR
                     DIQDPEVIKQFAEEVQTENRLRYLVCLTVADICATNETLWNSWKQSLLRELYFATEKQ
                     LRRGMQNTPDMRERVRHHQLQALALLRMDNIDEEVLHQIWSRCRANYFVRHSPNQLAW
                     HARHLLQHDLSKPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQI
                     FTTRDGMAMDTFIVLEPDGSPLSADRHEVIRFGLEQVLTQSSWQPPQPRRQPAKLRHF
                     TVETEVTFLPTHTDRKSFLELIALDQPGLLARVGKIFADLGISLHGARITTIGERVED
                     LFIIATADRRALNNELQQEVHQRLTEALNPNDKG"
     misc_feature    complement(189468..192119)
                     /gene="glnD"
                     /locus_tag="ECs_0169"
                     /note="bifunctional uridylyltransferase/uridylyl-removing
                     protein GlnD; Region: PRK05007"
                     /db_xref="CDD:235329"
     gene            complement(192199..192993)
                     /gene="map"
                     /locus_tag="ECs_0170"
                     /db_xref="GeneID:913847"
     CDS             complement(192199..192993)
                     /gene="map"
                     /locus_tag="ECs_0170"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine aminopeptidase"
                     /protein_id="NP_308197.1"
                     /db_xref="GeneID:913847"
                     /translation="MAISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRI
                     CNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIK
                     DGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAE
                     GFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMK
                     DGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE"
     misc_feature    complement(192232..192993)
                     /gene="map"
                     /locus_tag="ECs_0170"
                     /note="methionine aminopeptidase; Validated; Region:
                     PRK05716"
                     /db_xref="CDD:235576"
     misc_feature    complement(order(192289..192291,192382..192384,
                     192481..192483,192670..192672,192703..192705,
                     192757..192759))
                     /gene="map"
                     /locus_tag="ECs_0170"
                     /note="active site"
                     /db_xref="CDD:238519"
     gene            193361..194086
                     /gene="rpsB"
                     /locus_tag="ECs_0171"
                     /db_xref="GeneID:913849"
     CDS             193361..194086
                     /gene="rpsB"
                     /locus_tag="ECs_0171"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal subunit protein S2"
                     /protein_id="NP_308198.1"
                     /db_xref="GeneID:913849"
                     /translation="MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLE
                     KTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLT
                     NWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDA
                     LFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVA
                     ATVREGRSQDLASQAEESFVEAE"
     misc_feature    193361..194083
                     /gene="rpsB"
                     /locus_tag="ECs_0171"
                     /note="30S ribosomal protein S2; Provisional; Region:
                     rpsB; PRK05299"
                     /db_xref="CDD:235396"
     misc_feature    order(193433..193438,193463..193471,193643..193645,
                     193649..193657,193664..193669,193883..193885,
                     193892..193894)
                     /gene="rpsB"
                     /locus_tag="ECs_0171"
                     /note="rRNA interaction site [nucleotide binding]; other
                     site"
                     /db_xref="CDD:100106"
     misc_feature    order(193889..193894,193898..193900,193940..193951)
                     /gene="rpsB"
                     /locus_tag="ECs_0171"
                     /note="S8 interaction site [active]"
                     /db_xref="CDD:100106"
     misc_feature    193994..194011
                     /gene="rpsB"
                     /locus_tag="ECs_0171"
                     /note="putative laminin-1 binding site [active]"
                     /db_xref="CDD:100106"
     gene            194344..195195
                     /gene="tsf"
                     /locus_tag="ECs_0172"
                     /db_xref="GeneID:913854"
     CDS             194344..195195
                     /gene="tsf"
                     /locus_tag="ECs_0172"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor EF-Ts"
                     /protein_id="NP_308199.1"
                     /db_xref="GeneID:913854"
                     /translation="MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKS
                     GAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVA
                     GKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKG
                     ADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEG
                     RMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEV
                     AAMSKQS"
     misc_feature    194344..195186
                     /gene="tsf"
                     /locus_tag="ECs_0172"
                     /note="translation elongation factor Ts; Region: tsf;
                     TIGR00116"
                     /db_xref="CDD:272914"
     gene            195342..196067
                     /gene="pyrH"
                     /locus_tag="ECs_0173"
                     /db_xref="GeneID:913857"
     CDS             195342..196067
                     /gene="pyrH"
                     /locus_tag="ECs_0173"
                     /codon_start=1
                     /transl_table=11
                     /product="uridylate kinase"
                     /protein_id="NP_308200.1"
                     /db_xref="GeneID:913857"
                     /translation="MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKEL
                     VELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNA
                     RLMSAIPLNGVCDSYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADV
                     VLKATKVDGVFTADPAKDPTATMYEQLTYSEVLEKELKVMDLAAFTLARDHKLPIRVF
                     NMNKPGALRRVVMGEKEGTLITE"
     misc_feature    195369..196061
                     /gene="pyrH"
                     /locus_tag="ECs_0173"
                     /note="UMP kinase (UMPK)-Ec, the microbial/chloroplast
                     uridine monophosphate kinase (uridylate kinase) enzyme
                     that catalyzes UMP phosphorylation and plays a key role in
                     pyrimidine nucleotide biosynthesis; regulation of this
                     process is via feed-back control and...; Region:
                     AAK_UMPK-PyrH-Ec; cd04254"
                     /db_xref="CDD:239787"
     misc_feature    order(195384..195386,195393..195398,195507..195515,
                     195774..195779,195834..195839,195846..195848,
                     195852..195854,195858..195863)
                     /gene="pyrH"
                     /locus_tag="ECs_0173"
                     /note="putative nucleotide binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:239787"
     misc_feature    order(195507..195515,195525..195530,195570..195572,
                     195579..195584,195753..195755,195759..195764,
                     195768..195776)
                     /gene="pyrH"
                     /locus_tag="ECs_0173"
                     /note="uridine monophosphate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:239787"
     misc_feature    order(195546..195551,195573..195578,195597..195599,
                     195618..195620,195648..195650,195690..195692,
                     195702..195704,195711..195713,195729..195731,
                     195753..195755,195759..195767,195792..195794,
                     195801..195806,195972..195974)
                     /gene="pyrH"
                     /locus_tag="ECs_0173"
                     /note="homohexameric interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239787"
     gene            196217..196774
                     /gene="frr"
                     /locus_tag="ECs_0174"
                     /db_xref="GeneID:913872"
     CDS             196217..196774
                     /gene="frr"
                     /locus_tag="ECs_0174"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="NP_308201.1"
                     /db_xref="GeneID:913872"
                     /translation="MISDIRKDAEVRMDKCVEAFKTQISKIRTGRASPSLLDGIVVEY
                     YGTPTPLRQLASVTVEDSRTLKINVFDRSMSPAVEKAIMASDLGLNPNSAGSDIRVPL
                     PPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKEISEDDDRRSQDDV
                     QKLTDAAIKKIEAALADKEAELMQF"
     misc_feature    196217..196771
                     /gene="frr"
                     /locus_tag="ECs_0174"
                     /note="Ribosome recycling factor [Translation, ribosomal
                     structure and biogenesis]; Region: Frr; COG0233"
                     /db_xref="CDD:223311"
     gene            196866..198062
                     /gene="dxr"
                     /locus_tag="ECs_0175"
                     /db_xref="GeneID:913875"
     CDS             196866..198062
                     /gene="dxr"
                     /locus_tag="ECs_0175"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose 5-phosphate reductoisomerase"
                     /protein_id="NP_308202.1"
                     /db_xref="GeneID:913875"
                     /translation="MKQLTILGSTGSIGCSTLDVVRHNPEHFRVVALVAGKNVTRMVE
                     QCLEFSPRYAVMDDEASAKLLKTMLQQQGSRTEVLSGQQAACDMAALEDVDQVMAAIV
                     GAAGLLPTLAAIRAGKTILLANKESLVTCGRLFMDAVKQSKAQLLPVDSEHNAIFQSL
                     PQPIQHNLGYADLEQNGVVSILLTGSGGPFRETPLRDLATMTPDQACRHPNWSMGRKI
                     SVDSATMMNKGLEYIEARWLFNASASQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDM
                     RTPIAHTMAWPNRVNSGVKPLDFCKLSALTFAAPDYDRYPCLKLAMEAFEQGQAATTA
                     LNAANEITVAAFLAQQIRFTDIAALNLSVLEKMDMREPQCVDDVLSVDASAREVARKE
                     VMRLAS"
     misc_feature    196866..198059
                     /gene="dxr"
                     /locus_tag="ECs_0175"
                     /note="1-deoxy-D-xylulose 5-phosphate reductoisomerase;
                     Provisional; Region: PRK05447"
                     /db_xref="CDD:235472"
     gene            198251..199009
                     /gene="ispU"
                     /locus_tag="ECs_0176"
                     /db_xref="GeneID:913882"
     CDS             198251..199009
                     /gene="ispU"
                     /locus_tag="ECs_0176"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl pyrophosphate synthase"
                     /protein_id="NP_308203.2"
                     /db_xref="GeneID:913882"
                     /translation="MLSATQPLSEKLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHKA
                     GAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRH
                     NVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEK
                     VQQGNLQPDQIDEEMLNQHVCMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDV
                     LWPDFDEQDFEGALNAFANRERRFGGTEPGDETA"
     misc_feature    198320..199006
                     /gene="ispU"
                     /locus_tag="ECs_0176"
                     /note="(2E,6E)-farnesyl-diphosphate-specific
                     ditrans,polycis-undecaprenyl-diphosphate synthase; Region:
                     PRK10240"
                     /db_xref="CDD:182326"
     misc_feature    order(198320..198337,198362..198364,198374..198376,
                     198386..198388,198395..198397,198452..198454,
                     198476..198478,198488..198490,198509..198514,
                     198521..198523,198668..198670,198827..198829,
                     198845..198847,198851..198853)
                     /gene="ispU"
                     /locus_tag="ECs_0176"
                     /note="active site"
                     /db_xref="CDD:259850"
     misc_feature    order(198689..198694,198698..198703,198710..198715,
                     198761..198769,198776..198778,198809..198811,
                     198842..198856,198863..198871,198875..198889,
                     198893..198895)
                     /gene="ispU"
                     /locus_tag="ECs_0176"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:259850"
     gene            199052..199879
                     /gene="cdsA"
                     /locus_tag="ECs_0177"
                     /db_xref="GeneID:913883"
     CDS             199052..199879
                     /gene="cdsA"
                     /locus_tag="ECs_0177"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diglyceride synthase"
                     /protein_id="NP_308204.3"
                     /db_xref="GeneID:913883"
                     /translation="MLIPVVIAALFLLPPVGFAIVTLVVCMLAAWEWGQLSGFTTRSQ
                     RVWLAVLCGLLLALMLFLLPEYHRNIHQPLVEISLWASLGWWIVALLLVLFYPGSAAI
                     WRNSKTLRLIFGVLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMILVWGADSGAYM
                     FGKLFGKHKLAPKVSPGKTWQGFIGGLATAAVISWGYGMWANLDVAPVTLLICSIVAA
                     LASVLGDLTESMFKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLLLLVFRTL"
     misc_feature    199055..199876
                     /gene="cdsA"
                     /locus_tag="ECs_0177"
                     /note="phosphatidate cytidylyltransferase; Region: cdsA;
                     PRK11624"
                     /db_xref="CDD:183240"
     gene            199891..201243
                     /gene="rseP"
                     /locus_tag="ECs_0178"
                     /db_xref="GeneID:913885"
     CDS             199891..201243
                     /gene="rseP"
                     /locus_tag="ECs_0178"
                     /codon_start=1
                     /transl_table=11
                     /product="metallopeptidase"
                     /protein_id="NP_308205.1"
                     /db_xref="GeneID:913885"
                     /translation="MLSFLWDLASFIVALGVLITVHEFGHFWVARRCGVRVERFSIGF
                     GKALWRRTDKLGTEYVIALIPLGGYVKMLDERAEPVVPELRHHAFNNKSVGQRAAIIA
                     AGPVANFIFAIFAYWLVFIIGVPGVRPVVGEIAANSIAAEAQIAPGTELKAVDGIETP
                     DWDAVRLQLVDKIGDESTTITVAPFGSDQRRDVKLDLRHWAFEPDKEDPVSSLGIRPR
                     GPQIEPVLENVQPNSAASKAGLQAGDRIVKVDGQPLTQWVTFVMLVRDNPGKSLALEI
                     ERQGSPLSLTLIPESKPGNGKAIGFVGIEPKVIPLPDEYKVVRQYGPFNAIVEATDKT
                     WQLMKLTVSMLGKLITGDVKLNNLSGPISIAKGAGMTAELGVVYYLPFLALISVNLGI
                     INLFPLPVLDGGHLLFLAIEKIKGGPVSERVQDFCYRIGSILLVLLMGLALFNDFSRL
                     "
     misc_feature    199894..201240
                     /gene="rseP"
                     /locus_tag="ECs_0178"
                     /note="sigma E protease regulator RseP; Region: PRK10779"
                     /db_xref="CDD:182723"
     gene            201273..203705
                     /gene="bamA"
                     /locus_tag="ECs_0179"
                     /db_xref="GeneID:913887"
     CDS             201273..203705
                     /gene="bamA"
                     /locus_tag="ECs_0179"
                     /codon_start=1
                     /transl_table=11
                     /product="BamABCDE complex OM biogenesis outer membrane
                     pore-forming assembly factor"
                     /protein_id="NP_308206.1"
                     /db_xref="GeneID:913887"
                     /translation="MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALL
                     SMPVRTGDTVNDEDISNTIRALFATGNFEDVRVLRDGDTLLVQVKERPTIASITFSGN
                     KSVKDDMLKQNLEASGVRVGESLDRTTIADIEKGLEDFYYSVGKYSASVKAVVTPLPR
                     NRVDLKLVFQEGVSAEIQQINIVGNHAFTTDELISHFQLRDEVPWWNVVGDRKYQKQK
                     LAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYVTVNITEGDQYKLSGVEVSGN
                     LAGHSAEIEQLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQSMPEINDADKT
                     VKLRVNVDAGNRFYVRKIRFEGNDTSKDAVLRREMRQMEGAWLGSDLVDQGKERLNRL
                     GFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWL
                     GTGYAVGINGTKNDYQTYAELSVTNPYFTVDGVSLGGRLFYNDFQADDADLSDYTNKS
                     YGTDVTLGFPINEYNSLRAGLGYVHNSLSNMQPQVAMWRYLYSMGEHPSTSDQDNSFK
                     TDDFTFNYGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVTLDTATYVPIDDD
                     HKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYFPHQASNY
                     DPDYDYECATQDGAKDLCKSDDAVGGNAMAVASLEFITPTPFISDKYANSVRTSFFWD
                     MGTVWDTNWDSSQYSGYPDYSDPSNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDK
                     AEQFQFNIGKTW"
     misc_feature    201273..203702
                     /gene="bamA"
                     /locus_tag="ECs_0179"
                     /note="outer membrane protein assembly factor YaeT;
                     Provisional; Region: PRK11067"
                     /db_xref="CDD:236834"
     gene            203826..204311
                     /gene="skp"
                     /locus_tag="ECs_0180"
                     /db_xref="GeneID:913889"
     CDS             203826..204311
                     /gene="skp"
                     /locus_tag="ECs_0180"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic chaperone"
                     /protein_id="NP_308207.1"
                     /db_xref="GeneID:913889"
                     /translation="MKKWLLAAGLGLALATSAQAADKIAIVNMGSLFQQVAQKTGVSN
                     TLENEFKGRASELQRMETDLQAKMKKLQSMKAGSDRTKLEKDVMAQRQTFAQKAQAFE
                     QDRARRSNEERGKLVTRIQTAVKSVANSQDIDLVVDANAVAYNSSDVKDITADVLKQV
                     K"
     misc_feature    203826..204308
                     /gene="skp"
                     /locus_tag="ECs_0180"
                     /note="molecular chaperone Skp; Region: PRK10780"
                     /db_xref="CDD:182724"
     gene            204315..205340
                     /gene="lpxD"
                     /locus_tag="ECs_0181"
                     /db_xref="GeneID:913891"
     CDS             204315..205340
                     /gene="lpxD"
                     /locus_tag="ECs_0181"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-(3-hydroxymyristoyl)-glucosamine
                     N-acyltransferase"
                     /protein_id="NP_308208.1"
                     /db_xref="GeneID:913891"
                     /translation="MPSIRLADLAQQLDAELHGDGDIVITGVASMQSAQTGHITFMVN
                     PKYREHLGLCQASAVVMTQDDLPFAKSAALVVKNPYLTYARMAQILDTTPQPAQNIAP
                     SAVIDATAKLGNNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGAGSRLWANVTI
                     YHEIQIGQNCLIQSGTVVGADGFGYANDRGNWVKIPQIGRVIIGDRVEIGACTTIDRG
                     ALDDTVIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKIGRYCMIGGASVINGH
                     MEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKTAALVMNIDDMSKRLKSLE
                     RKVNQQD"
     misc_feature    204318..205334
                     /gene="lpxD"
                     /locus_tag="ECs_0181"
                     /note="UDP-3-O-[3-hydroxymyristoyl] glucosamine
                     N-acyltransferase; Provisional; Region: lpxD; PRK00892"
                     /db_xref="CDD:234858"
     gene            205445..205900
                     /gene="fabZ"
                     /locus_tag="ECs_0182"
                     /db_xref="GeneID:913892"
     CDS             205445..205900
                     /gene="fabZ"
                     /locus_tag="ECs_0182"
                     /codon_start=1
                     /transl_table=11
                     /product="(3R)-hydroxymyristoyl-[acyl carrier protein]
                     dehydratase"
                     /protein_id="NP_308209.2"
                     /db_xref="GeneID:913892"
                     /translation="MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNV
                     SVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFK
                     RPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA"
     misc_feature    205448..205894
                     /gene="fabZ"
                     /locus_tag="ECs_0182"
                     /note="3-hydroxyacyl-ACP dehydratase FabZ; Region: fabZ;
                     PRK00006"
                     /db_xref="CDD:234568"
     gene            205904..206692
                     /gene="lpxA"
                     /locus_tag="ECs_0183"
                     /db_xref="GeneID:913893"
     CDS             205904..206692
                     /gene="lpxA"
                     /locus_tag="ECs_0183"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine acetyltransferase"
                     /protein_id="NP_308210.1"
                     /db_xref="GeneID:913893"
                     /translation="MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVL
                     KSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGT
                     VQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMAAVH
                     QFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNA
                     YKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR"
     misc_feature    205913..206689
                     /gene="lpxA"
                     /locus_tag="ECs_0183"
                     /note="acyl-ACP--UDP-N-acetylglucosamine
                     O-acyltransferase; Region: PRK05289"
                     /db_xref="CDD:235390"
     gene            206692..207840
                     /gene="lpxB"
                     /locus_tag="ECs_0184"
                     /db_xref="GeneID:913894"
     CDS             206692..207840
                     /gene="lpxB"
                     /locus_tag="ECs_0184"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-A-disaccharide synthase"
                     /protein_id="NP_308211.1"
                     /db_xref="GeneID:913894"
                     /translation="MTEQRPLTIALVAGETSGDILGAGLIRALKERVPNARFVGVAGP
                     RMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDVFVGIDAPDF
                     NIILEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVP
                     CRFIGHTMADAMPLDPDKNSARDVLGIPYDAHCLALLPGSRGAEVEMLSADFLKTAQL
                     LRQTYPDLEIVVPLVNAKRREQFERIKAAVAPDLSVHLLDGMGREAMVASDAALLASG
                     TAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVKELLQEECEP
                     QKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ"
     misc_feature    206692..207831
                     /gene="lpxB"
                     /locus_tag="ECs_0184"
                     /note="lipid-A-disaccharide synthase; Region: lpxB;
                     TIGR00215"
                     /db_xref="CDD:129319"
     gene            207837..208433
                     /gene="rnhB"
                     /locus_tag="ECs_0185"
                     /db_xref="GeneID:913902"
     CDS             207837..208433
                     /gene="rnhB"
                     /locus_tag="ECs_0185"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="NP_308212.1"
                     /db_xref="GeneID:913902"
                     /translation="MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLN
                     DSKKLSEKRRLALCEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAP
                     EYVLIDGNRCPKLPMPAMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFA
                     QHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS"
     misc_feature    207864..208406
                     /gene="rnhB"
                     /locus_tag="ECs_0185"
                     /note="ribonuclease HII; Validated; Region: rnhB;
                     PRK00015"
                     /db_xref="CDD:234574"
     misc_feature    order(207882..207899,207975..207977,208080..208088,
                     208158..208166,208203..208208,208212..208214,
                     208254..208256,208317..208325,208329..208337,
                     208395..208403)
                     /gene="rnhB"
                     /locus_tag="ECs_0185"
                     /note="RNA/DNA hybrid binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:260003"
     gene            208470..211952
                     /gene="dnaE"
                     /locus_tag="ECs_0186"
                     /db_xref="GeneID:913906"
     CDS             208470..211952
                     /gene="dnaE"
                     /locus_tag="ECs_0186"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III alpha subunit DnaE"
                     /protein_id="NP_308213.1"
                     /db_xref="GeneID:913906"
                     /translation="MSEPRFVHLRVHSDYSMIDGLAKTAPLVKKAAALGMPALAITDF
                     TNLCGLVKFYGAGHGAGIKPIVGADFNVQCDLLGDELTHLTVLAANNTGYQNLTLLIS
                     KAYQRGYGAAGPIIDRDWLIELNEGLILLSGGRMGDVGRSLLRGNSALVDECVAFYEE
                     HFPDRYFLELIRTGRPDEESYLHAAVELAEARGLPVVATNDVRFIDSSDFDAHEIRVA
                     IHDGFTLDDPKRPRNYSPQQYMRSEEEMCELFADIPEALANTVEIAKRCNVTVRLGEY
                     FLPQFPTGDMSTEDYLVKRAKEGLEERLAFLFPDEEERVKRRPEYDERLETELQVINQ
                     MGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFL
                     NPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLG
                     HPYGFVDRISKLIPPDPGMTLAKAFEAEPQLPEIYEADEEVKALIDMARKLEGVTRNA
                     GKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYAGLVKFDFLGLRTLTIIN
                     WALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVFQLESRGMKDLIKRLQ
                     PDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREEISYPDVQWQHESLKPVLEPTYG
                     IILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFAEGAEKNGINAEL
                     AMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTADMDNTEKVV
                     GLVDECWRMGLKILPPDINSGLYHFHVNDDGEIVYGIGAIKGVGEGPIEAIIEARNKG
                     GYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLGDALKAADQHAK
                     AEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTGHPINQYLKE
                     IERYVGGVRLKDMHPTERGKVITAAGLVVAARVMVTKRGNRIGICTLDDRSGRLEVML
                     FTDALDKYQHLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARGLAISL
                     TDRQIDDQLLNRLRQSLEPHRSGTIPVHLYYQRADARARLRFGATWRVSPSDRLLNDL
                     RGLIGSEQVELEFD"
     misc_feature    208482..211922
                     /gene="dnaE"
                     /locus_tag="ECs_0186"
                     /note="DNA polymerase III subunit alpha; Validated;
                     Region: dnaE; PRK05673"
                     /db_xref="CDD:235554"
     gene            211965..212924
                     /gene="accA"
                     /locus_tag="ECs_0187"
                     /db_xref="GeneID:913907"
     CDS             211965..212924
                     /gene="accA"
                     /locus_tag="ECs_0187"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     alpha subunit"
                     /protein_id="NP_308214.1"
                     /db_xref="GeneID:913907"
                     /translation="MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLR
                     EKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIV
                     GGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITF
                     IDTPGAYPGVGAEERGQSEAIARNLREMSRLGVPVVCTVIGEGGSGGALAIGVGDKVN
                     MLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAH
                     RNPEAMAASLKAQLLADLADLDVLSTEDLKNRRYQRLMSYGYA"
     misc_feature    211965..212918
                     /gene="accA"
                     /locus_tag="ECs_0187"
                     /note="acetyl-CoA carboxylase carboxyltransferase subunit
                     alpha; Validated; Region: PRK05724"
                     /db_xref="CDD:235580"
     gene            213023..215164
                     /gene="cadA_1"
                     /locus_tag="ECs_0188"
                     /db_xref="GeneID:913910"
     CDS             213023..215164
                     /gene="cadA_1"
                     /locus_tag="ECs_0188"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase 2"
                     /protein_id="NP_308215.1"
                     /db_xref="GeneID:913910"
                     /translation="MNIIAIMGPHGVFYKDEPIKELESALVAQGFQIIWPQNSVDLLK
                     FIEHNPRICGVIFDWDEYSLDLCSDINQLNEYLPLYAFINTHSTMDVSVQDMRMALCF
                     FEYALGQAEDIAIRMRQYTDEYLDNITPPFTKALFTYVKERKYTFCTPGHMGGTAYQK
                     SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYIVTN
                     GTSTSNKIVGMYAAPSGSTLLIDRNCHKSLAHLLMMNDVVPVWLKPTRNALGILGGIP
                     RREFTRDSIEEKVAATTQAQWPVHAVITNSTYDGLLYNTDWIKQTLDVPSIHFDSAWV
                     PYTHFHPIYQGKSGMSGERVAGKVIFETQSTHKMLAALSQASLIHIKGEYDEEAFNEA
                     FMMHTTTSPSYPIVASVETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDGWF
                     FDIWQPPQVDEAECWPVAPGEQWHGFNDADADHMFLDPVKVTILTPGMDEQGNMSEEG
                     IPAALVAKFLDERGIVVEKTGPYNLLFLFSIGIDKTKAMGLLRGLTEFKRSYDLNLRI
                     KNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRKHDLPGLMLRAFDTLPEMIMTPHQAW
                     QRQIKGEVETIALEQLVGRVSANMILPYPPGVPLLMPGEMLTKESRTVLDFLLMLCSV
                     GQHYPGFETDIHGAKQDEDGVYRVRVLKMAG"
     misc_feature    213023..215161
                     /gene="cadA_1"
                     /locus_tag="ECs_0188"
                     /note="lysine decarboxylase; Region: PRK15399"
                     /db_xref="CDD:185297"
     gene            215221..215610
                     /gene="yaeR"
                     /locus_tag="ECs_0189"
                     /db_xref="GeneID:913914"
     CDS             215221..215610
                     /gene="yaeR"
                     /locus_tag="ECs_0189"
                     /codon_start=1
                     /transl_table=11
                     /product="lyase"
                     /protein_id="NP_308216.2"
                     /db_xref="GeneID:913914"
                     /translation="MLGLKQVHHIAIIATDYAVSKAFYCDILGFTLQSEVYREARDSW
                     KGDLALNGQYVIELFSFPFPPERPSRPEACGLRHLAFSVDDIDAAVAHLESHNVKCEA
                     IRVDPYTQKRFTFFNDPDGLPLELYEQ"
     misc_feature    215221..215607
                     /gene="yaeR"
                     /locus_tag="ECs_0189"
                     /note="VOC family protein; Region: PRK11478"
                     /db_xref="CDD:183156"
     gene            215675..216970
                     /gene="tilS"
                     /locus_tag="ECs_0190"
                     /db_xref="GeneID:913916"
     CDS             215675..216970
                     /gene="tilS"
                     /locus_tag="ECs_0190"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(Ile)-lysidine synthetase"
                     /protein_id="NP_308217.1"
                     /db_xref="GeneID:913916"
                     /translation="MTLTLNRQLLTSRQILVAFSGGLDSTVLLHQLVQWRTENPGGAL
                     RAIHVHHGLSANADAWVTHCENVCQQWQVPLVVERVQLAQEGLGIEAQARQARYQAFA
                     RTLLPGEVLVTAQHLDDQCETFLLALKRGSGPAGLSAMAEVSEFAGTRLIRPLLARTR
                     GELAQWALAHGLRWIEDESNQDDSYDRNFLRLRVVPLLQQRWPHFAETTARSAALCAE
                     QESLLDELLADDLAHCQSPQGTLQIVPMLAMSDARRAAIIRRWLAGQNAPMPSRDALV
                     RIWQEVALAREDASPCLRLGAFEIRRYQSQLWWIKSVTGQSENIVPWQTWLQPLELPA
                     GQGSVQLNAGGDIRPPRADEAVSVRFKAPGLLHIVGRNGGRKLKKIWQELGVPPWLRD
                     TTPLLFYGETLIAAAGGFVTQEGVAEGENGISFVWQRNA"
     misc_feature    215675..216964
                     /gene="tilS"
                     /locus_tag="ECs_0190"
                     /note="tRNA(Ile)-lysidine synthetase; Provisional; Region:
                     tilS; PRK10660"
                     /db_xref="CDD:182626"
     misc_feature    order(215726..215734,215738..215749,215816..215818,
                     215822..215824)
                     /gene="tilS"
                     /locus_tag="ECs_0190"
                     /note="Ligand Binding Site [chemical binding]; other site"
                     /db_xref="CDD:238950"
     gene            complement(217023..217283)
                     /gene="rof"
                     /locus_tag="ECs_0191"
                     /db_xref="GeneID:913917"
     CDS             complement(217023..217283)
                     /gene="rof"
                     /locus_tag="ECs_0191"
                     /codon_start=1
                     /transl_table=11
                     /product="modulator of Rho-dependent transcription
                     termination"
                     /protein_id="NP_308218.3"
                     /db_xref="GeneID:913917"
                     /translation="MSMNDTYQPINCDDYDNLELACQHHLMLTLELKDGEKLQAKASD
                     LVSRKNVEYLVVEAAGETRELRLDKITSFSHPEIGTVVVSES"
     misc_feature    complement(217026..217277)
                     /gene="rof"
                     /locus_tag="ECs_0191"
                     /note="Rho-binding antiterminator; Provisional; Region:
                     PRK11625"
                     /db_xref="CDD:183241"
     gene            complement(217270..217470)
                     /gene="yaeP"
                     /locus_tag="ECs_5365"
                     /db_xref="GeneID:62676003"
     CDS             complement(217270..217470)
                     /gene="yaeP"
                     /locus_tag="ECs_5365"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_009502588.1"
                     /db_xref="GeneID:62676003"
                     /translation="MEKYCELIRKRYAEIASGDLGYVPDALGCVLKVLNEMAADDALS
                     EAVREKAAYAAANLLVSDYVNE"
     misc_feature    complement(217273..217470)
                     /gene="yaeP"
                     /locus_tag="ECs_5365"
                     /note="hypothetical protein; Provisional; Region:
                     PRK04964"
                     /db_xref="CDD:179901"
     gene            217636..218094
                     /gene="yaeQ"
                     /locus_tag="ECs_0192"
                     /db_xref="GeneID:913918"
     CDS             217636..218094
                     /gene="yaeQ"
                     /locus_tag="ECs_0192"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308219.1"
                     /db_xref="GeneID:913918"
                     /translation="MALKATIYKATVNVADLDRNQFLDASLTLARHPSETQERMMLRL
                     LAWLKYADERLQFTRGLCADDEPEAWLRNDHLGIDLWIELGLPDERRIKKACTQAAEV
                     ALFTYNSRAAQIWWQQNQSKCAQFANLSVWYLDDEQLAKVSAFADRTMTL"
     misc_feature    217636..218091
                     /gene="yaeQ"
                     /locus_tag="ECs_0192"
                     /note="YaeQ protein; Region: YaeQ; cl01913"
                     /db_xref="CDD:445604"
     gene            218178..218588
                     /gene="arfB"
                     /locus_tag="ECs_0193"
                     /db_xref="GeneID:913932"
     CDS             218178..218588
                     /gene="arfB"
                     /locus_tag="ECs_0193"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308220.1"
                     /db_xref="GeneID:913932"
                     /translation="MIVISRHVAIPDGELEITAIRAQGAGGQHVNKTSTAIHLRFDIR
                     ASSLPEYYKERLLAASHHLISSDGVIVIKAQEYRSQELNREAALARLVAVIKDLTTEQ
                     KARRPTRPTRASKERRLASKAQKSSVKAMRSGRE"
     misc_feature    218178..218582
                     /gene="arfB"
                     /locus_tag="ECs_0193"
                     /note="aminoacyl-tRNA hydrolase; Region: PRK09256"
                     /db_xref="CDD:181730"
     gene            218602..219312
                     /gene="nlpE"
                     /locus_tag="ECs_0194"
                     /db_xref="GeneID:913936"
     CDS             218602..219312
                     /gene="nlpE"
                     /locus_tag="ECs_0194"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein involved with copper homeostasis and
                     adhesion"
                     /protein_id="NP_308221.1"
                     /db_xref="GeneID:913936"
                     /translation="MVKKAIVTAMAVISLFTLMGCNNRAEVDTLSPAQAAELKPMPQS
                     WRGVLPCADCEGIETSLFLEKDGTWVMNERYLGAREEPSSFASYGTWARTADKLVLTD
                     SKGEKSYYRAKGDALEMLDREGNPIESQFNYTLEPAQSSLPMTPMTLRGMYFYMADAA
                     TFTDCATGKRFMVANNAELERGYLAARGHSEKPVLLSVEGHFTLEANPDTGAPTKVLA
                     PDTAGKFYPNQDCSSLGQ"
     misc_feature    218602..219300
                     /gene="nlpE"
                     /locus_tag="ECs_0194"
                     /note="envelope stress response activation lipoprotein
                     NlpE; Region: PRK10523"
                     /db_xref="CDD:236708"
     gene            complement(219512..220336)
                     /gene="yaeF"
                     /locus_tag="ECs_0195"
                     /db_xref="GeneID:913937"
     CDS             complement(219512..220336)
                     /gene="yaeF"
                     /locus_tag="ECs_0195"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="NP_308222.1"
                     /db_xref="GeneID:913937"
                     /translation="MDKPKAYCRLLLPCFLLLSACTVDISQPDSSATAVDAEAKTWAV
                     KFQHQSSFTEQSIKEITVPDLKPGDLLFSSSLEVTSFGIRVFSTSSVSHVAIYLGENN
                     VAEATGAGVQIVSLKKAMKHSDKLFVLRVPDLTPQQATEITAFANKIKDSGYNYRGIV
                     EFIPFMVTRQMCSLNPFSEDFRQQCVSGLAKAQLSSVVEGDKKSWFCSEFVTDAFAKA
                     GHPLTLAQSGWISPADLMHMRIGDVSAFKPETQLQYVGHLKPGIYIKAGRFVGLTR"
     misc_feature    complement(219515..220336)
                     /gene="yaeF"
                     /locus_tag="ECs_0195"
                     /note="YaeF family permuted papain-like enzyme; Region:
                     PRK11479"
                     /db_xref="CDD:183157"
     gene            complement(220389..222107)
                     /gene="proS"
                     /locus_tag="ECs_0196"
                     /db_xref="GeneID:913939"
     CDS             complement(220389..222107)
                     /gene="proS"
                     /locus_tag="ECs_0196"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase"
                     /protein_id="NP_308223.1"
                     /db_xref="GeneID:913939"
                     /translation="MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLP
                     TGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGER
                     PFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDA
                     YSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGE
                     DDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIKK
                     TVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAG
                     PGSLGPVNMPIPVVIDRTVAAMSDFTAGANIDGKHYFGINWDRDVATPEVADIRNVVA
                     GDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTR
                     VVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVL
                     LDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVEYL
                     VKQIKG"
     misc_feature    complement(220395..222107)
                     /gene="proS"
                     /locus_tag="ECs_0196"
                     /note="prolyl-tRNA synthetase; Provisional; Region:
                     PRK09194"
                     /db_xref="CDD:236405"
     gene            complement(222218..222925)
                     /gene="tsaA"
                     /locus_tag="ECs_0197"
                     /db_xref="GeneID:913945"
     CDS             complement(222218..222925)
                     /gene="tsaA"
                     /locus_tag="ECs_0197"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase"
                     /protein_id="NP_308224.1"
                     /db_xref="GeneID:913945"
                     /translation="MSSFQFEQIGVIRSPYKEKFAVPRQPGLVKSANGELHLIAPYNQ
                     ADAVRGLEAFSHLWILFVFHQTMEGGWRPTVRPPRLGGNARMGVFATRSTFRPNPIGM
                     SLVELKEVVCHKDCVILKLGSLDLVDGTPVVDIKPYLPFAESLPDASASYAQSAPAAE
                     MAVSFTAEVEKQLLTLEKRYPQLTLFIREVLAQDPRPAYRKGEETGKTYAVWLHDFNV
                     RWRVTDAGFEVFALEPR"
     misc_feature    complement(222455..222919)
                     /gene="tsaA"
                     /locus_tag="ECs_0197"
                     /note="tRNA (Thr-GGU) A37 N-methylase [Translation,
                     ribosomal structure and biogenesis]; Region: TsaA;
                     COG1720"
                     /db_xref="CDD:224634"
     misc_feature    complement(order(222512..222529,222626..222628,
                     222632..222634,222638..222640,222650..222667,
                     222740..222742,222752..222754,222773..222775,
                     222779..222787,222899..222901))
                     /gene="tsaA"
                     /locus_tag="ECs_0197"
                     /note="homodimer interaction site [polypeptide binding];
                     other site"
                     /db_xref="CDD:187753"
     misc_feature    complement(order(222536..222538,222551..222553,
                     222620..222622,222626..222628,222650..222652,
                     222734..222739,222743..222745))
                     /gene="tsaA"
                     /locus_tag="ECs_0197"
                     /note="cofactor binding site [active]"
                     /db_xref="CDD:187753"
     misc_feature    complement(222257..222451)
                     /gene="tsaA"
                     /locus_tag="ECs_0197"
                     /note="TrmO C-terminal domain; Region: TrmO_C; pfam18389"
                     /db_xref="CDD:436459"
     gene            complement(222922..223326)
                     /gene="rcsF"
                     /locus_tag="ECs_0198"
                     /db_xref="GeneID:913950"
     CDS             complement(222922..223326)
                     /gene="rcsF"
                     /locus_tag="ECs_0198"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein"
                     /protein_id="NP_308225.1"
                     /db_xref="GeneID:913950"
                     /translation="MRALPICLVALMLSGCSMLSRSPVEPVQSTAPQPKAEPAKPKAP
                     RATPVRIYTNAEELVGKPFRDLGEVSGDSCQASNQDSPPSIPTARKRMQINASKMKAN
                     AVLLHSCEVTSGTPGCYRQALCIGSALNITAK"
     misc_feature    complement(222928..223326)
                     /gene="rcsF"
                     /locus_tag="ECs_0198"
                     /note="Rcs stress response system protein RcsF; Region:
                     rcsF; PRK10781"
                     /db_xref="CDD:182725"
     gene            complement(223444..224259)
                     /gene="metQ"
                     /locus_tag="ECs_0199"
                     /db_xref="GeneID:913959"
     CDS             complement(223444..224259)
                     /gene="metQ"
                     /locus_tag="ECs_0199"
                     /codon_start=1
                     /transl_table=11
                     /product="DL-methionine transporter subunit"
                     /protein_id="NP_308226.1"
                     /db_xref="GeneID:913959"
                     /translation="MAFKFKTFAAVGALIGSLALVGCGQDEKDPNHIKVGVIVGAEQQ
                     VAEVAQKVAKDKYGLDVELVTFNDYVLPNEALSKGDIDANAFQHKPYLDQQLKDRGYK
                     LVAVGNTFVYPIAGYSKKIKSLDELQDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKDG
                     VGLLPTVLDVVENPKNLKIVELEAPQLPRSLDDAQIALAVINTTYASQIGLTPAKNGI
                     FVEDKDSPYVNLIVTREDNKDAENVKKFVQAYQSDEVYEAANKVFNGGAVKGW"
     misc_feature    complement(223447..224259)
                     /gene="metQ"
                     /locus_tag="ECs_0199"
                     /note="D-methionine ABC transporter substrate-binding
                     protein MetQ; Region: metQ; PRK11063"
                     /db_xref="CDD:182939"
     misc_feature    complement(order(223573..223575,223648..223650,
                     223654..223656,223828..223830,223837..223839,
                     223924..223926,223987..223989,223996..224004,
                     224053..224055))
                     /gene="metQ"
                     /locus_tag="ECs_0199"
                     /note="chemical substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:270316"
     gene            complement(224299..224952)
                     /gene="metI"
                     /locus_tag="ECs_0200"
                     /db_xref="GeneID:913960"
     CDS             complement(224299..224952)
                     /gene="metI"
                     /locus_tag="ECs_0200"
                     /codon_start=1
                     /transl_table=11
                     /product="DL-methionine transporter subunit"
                     /protein_id="NP_308227.1"
                     /db_xref="GeneID:913960"
                     /translation="MSEPMMWLLVRGVWETLAMTFVSGFFGFVVGLPVGVLLYVTRPG
                     QIIANAKLYRTVSAIVNIFRSIPFIILLVWMIPFTRVIVGTSIGLQAAIVPLTVGAAP
                     FIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGY
                     SAMGGAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVILVYLIQFAGDRIVRAVTRK"
     misc_feature    complement(224302..224952)
                     /gene="metI"
                     /locus_tag="ECs_0200"
                     /note="D-methionine ABC transporter permease MetI; Region:
                     PRK10782"
                     /db_xref="CDD:182726"
     misc_feature    complement(order(224461..224478,224725..224769))
                     /gene="metI"
                     /locus_tag="ECs_0200"
                     /note="conserved gate region [active]"
                     /db_xref="CDD:119394"
     misc_feature    complement(order(224530..224532,224542..224547,
                     224563..224601))
                     /gene="metI"
                     /locus_tag="ECs_0200"
                     /note="ABC-ATPase subunit interface [active]"
                     /db_xref="CDD:119394"
     gene            complement(224945..225976)
                     /gene="metN"
                     /locus_tag="ECs_0201"
                     /db_xref="GeneID:913972"
     CDS             complement(224945..225976)
                     /gene="metN"
                     /locus_tag="ECs_0201"
                     /codon_start=1
                     /transl_table=11
                     /product="DL-methionine transporter subunit"
                     /protein_id="NP_308228.1"
                     /db_xref="GeneID:913972"
                     /translation="MIKLSNITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGK
                     STLIRCVNLLERPTEGSVLVDGQELTTLSESELTKARRQIGMIFQHFNLLSSRTVFGN
                     VALPLELDNTPKDEIKRRVTELLSLVGLGDKHDSYPSNLSGGQKQRVAIARALASNPK
                     VLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVISNGE
                     LIEQDTVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQ
                     SVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHH
                     VKVEVLGYV"
     misc_feature    complement(224948..225976)
                     /gene="metN"
                     /locus_tag="ECs_0201"
                     /note="DL-methionine transporter ATP-binding subunit;
                     Provisional; Region: metN; PRK11153"
                     /db_xref="CDD:236863"
     gene            226164..226739
                     /gene="gmhB"
                     /locus_tag="ECs_0202"
                     /db_xref="GeneID:913974"
     CDS             226164..226739
                     /gene="gmhB"
                     /locus_tag="ECs_0202"
                     /codon_start=1
                     /transl_table=11
                     /product="D,D-heptose 1,7-bisphosphate phosphatase"
                     /protein_id="NP_308229.1"
                     /db_xref="GeneID:913974"
                     /translation="MAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKK
                     MGFALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRDVDLDGIYYCPHHPQGSVEE
                     FRQVCDCRKPHPGMLLSARDYLHIDMAASYMVGDKLEDMQAAVAANVGTKVLVRTGKP
                     ITPEAENAADWVLNSLADLPQAIKKQQKPAQ"
     misc_feature    226176..226706
                     /gene="gmhB"
                     /locus_tag="ECs_0202"
                     /note="D,D-heptose 1,7-bisphosphate phosphatase; Region:
                     GmhB_yaeD; TIGR00213"
                     /db_xref="CDD:129317"
     gene            227106..228643
                     /gene="rrsH"
                     /locus_tag="ECs_R0001"
                     /db_xref="GeneID:62676004"
     rRNA            227106..228643
                     /gene="rrsH"
                     /locus_tag="ECs_R0001"
                     /product="16S ribosomal RNA"
                     /db_xref="GeneID:62676004"
     gene            228713..228789
                     /gene="ileV"
                     /locus_tag="ECs_R0024"
                     /db_xref="GeneID:62676005"
     tRNA            228713..228789
                     /gene="ileV"
                     /locus_tag="ECs_R0024"
                     /product="tRNA-Ile"
                     /note="anticodon: gat"
                     /db_xref="GeneID:62676005"
     gene            228832..228907
                     /gene="alaV"
                     /locus_tag="ECs_R0025"
                     /db_xref="GeneID:62676006"
     tRNA            228832..228907
                     /gene="alaV"
                     /locus_tag="ECs_R0025"
                     /product="tRNA-Ala"
                     /note="anticodon: tgc"
                     /db_xref="GeneID:62676006"
     gene            229093..231992
                     /gene="rrlH"
                     /locus_tag="ECs_R0002"
                     /db_xref="GeneID:62676007"
     rRNA            229093..231992
                     /gene="rrlH"
                     /locus_tag="ECs_R0002"
                     /product="23S ribosomal RNA"
                     /db_xref="GeneID:62676007"
     gene            232090..232200
                     /gene="rrfH"
                     /locus_tag="ECs_R0003"
                     /db_xref="GeneID:62676008"
     rRNA            232090..232200
                     /gene="rrfH"
                     /locus_tag="ECs_R0003"
                     /product="5S ribosomal RNA"
                     /db_xref="GeneID:62676008"
     gene            232258..232334
                     /gene="aspU"
                     /locus_tag="ECs_R0026"
                     /db_xref="GeneID:62676009"
     tRNA            232258..232334
                     /gene="aspU"
                     /locus_tag="ECs_R0026"
                     /product="tRNA-Asp"
                     /note="anticodon: gtc"
                     /db_xref="GeneID:62676009"
     gene            232497..233300
                     /gene="dkgB"
                     /locus_tag="ECs_0203"
                     /db_xref="GeneID:914031"
     CDS             232497..233300
                     /gene="dkgB"
                     /locus_tag="ECs_0203"
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-diketo-D-gluconate reductase B"
                     /protein_id="NP_308230.1"
                     /db_xref="GeneID:914031"
                     /translation="MAIPAFGLGTFRLKDDVVISSVKTALELGYRAIDTAQIYDNEAA
                     VGLAIAESGVPRHELYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWPSPN
                     DEVSVEEFMQALLEAKKEGLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQ
                     NRKVVAWAKQHGIHITSYMTLAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSV
                     IPSSTKRENLESNLKAQNLQLDAEDKKAIAALDCNDRLVSPEGLAPEWD"
     misc_feature    232497..233297
                     /gene="dkgB"
                     /locus_tag="ECs_0203"
                     /note="2,5-didehydrogluconate reductase DkgB; Region:
                     dkgB; PRK11172"
                     /db_xref="CDD:183012"
     misc_feature    order(232521..232529,232596..232598,232608..232613,
                     232686..232688,232785..232790,232881..232886,
                     232950..232952,233028..233048,233070..233072,
                     233106..233108,233151..233168,233175..233177,
                     233184..233189)
                     /gene="dkgB"
                     /locus_tag="ECs_0203"
                     /note="putative active site [active]"
                     /db_xref="CDD:381365"
     misc_feature    order(232596..232598,232611..232613,232686..232688,
                     232785..232787)
                     /gene="dkgB"
                     /locus_tag="ECs_0203"
                     /note="catalytic tetrad [active]"
                     /db_xref="CDD:381365"
     gene            complement(233297..234211)
                     /gene="yafC"
                     /locus_tag="ECs_0204"
                     /db_xref="GeneID:914036"
     CDS             complement(233297..234211)
                     /gene="yafC"
                     /locus_tag="ECs_0204"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="NP_308231.1"
                     /db_xref="GeneID:914036"
                     /translation="MKATSEELAIFVSVVESGSFSRAAEQLGQANSAVSRAVKKLEMK
                     LGVSLLNRTTRQLSLTEEGERYFRRVQSILQEMAAAESEIMETRNTPRGLLRIDAATP
                     VVLHFLMPLIKPFRERYPEVTLSLVSSETIINLIERKVDVAIRAGTLTDSSLRARPLF
                     NSYRKIIASPDYISRYGKPETIDDLKQHVCLGFTEPASLNTWPVACSDGQLHEVKYGL
                     SSNSGETLKQLCLSGNGIACLSDYMIDREIARGELVELMADKVLPVEMPFSAVYYSDR
                     AVSTRIRAFIDFLSEHVKTAPGGAVREA"
     misc_feature    complement(<233780..234181)
                     /gene="yafC"
                     /locus_tag="ECs_0204"
                     /note="DNA-binding transcriptional regulator CynR;
                     Provisional; Region: PRK11242"
                     /db_xref="CDD:183051"
     misc_feature    complement(233345..233941)
                     /gene="yafC"
                     /locus_tag="ECs_0204"
                     /note="The C-terminal substrate binding domain of
                     LysR-type transcriptional regulator CrgA, contains the
                     type 2 periplasmic binding domain; Region: PBP2_CrgA;
                     cd08478"
                     /db_xref="CDD:176167"
     misc_feature    complement(order(233408..233410,233492..233494,
                     233543..233545,233726..233728,233732..233734,
                     233774..233776,233891..233893,233903..233905))
                     /gene="yafC"
                     /locus_tag="ECs_0204"
                     /note="putative effector binding pocket [active]"
                     /db_xref="CDD:176167"
     misc_feature    complement(order(233516..233518,233525..233530,
                     233549..233563,233645..233647,233828..233848,
                     233852..233854,233864..233866,233873..233878,
                     233882..233887,233897..233902))
                     /gene="yafC"
                     /locus_tag="ECs_0204"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:176167"
     gene            234473..235252
                     /gene="yafD"
                     /locus_tag="ECs_0205"
                     /db_xref="GeneID:914037"
     CDS             234473..235252
                     /gene="yafD"
                     /locus_tag="ECs_0205"
                     /codon_start=1
                     /transl_table=11
                     /product="endo/exonuclease/phosphatase family protein"
                     /protein_id="NP_308232.2"
                     /db_xref="GeneID:914037"
                     /translation="MRYVAGQPAERILPPGSFASIGQALPPGEPLSTEERIRILVWNI
                     YKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFVLPQHPSG
                     VMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNIHAVNFSLGVDVY
                     SKQLLPIGDQIAHHSGPVIMAGDFNAWSRRRMNALYRFAREMSLRQVRFTDDQRRRAF
                     GRPLDFVFYRGLNVSEASVLVTRASDHNPLLVEFSPGKPDK"
     misc_feature    234473..235240
                     /gene="yafD"
                     /locus_tag="ECs_0205"
                     /note="endonuclease/exonuclease/phosphatase family
                     protein; Region: PRK05421"
                     /db_xref="CDD:235454"
     gene            235330..236100
                     /gene="yafE"
                     /locus_tag="ECs_0206"
                     /db_xref="GeneID:914039"
     CDS             235330..236100
                     /gene="yafE"
                     /locus_tag="ECs_0206"
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-L-methionine-dependent
                     methyltransferase"
                     /protein_id="NP_308233.1"
                     /db_xref="GeneID:914039"
                     /translation="MTTQSHHDHVEKQFSSQASEYLTSTVHASGRDLQLLAVCLADYP
                     DASVLDMGCGAGHASFVAAQNVSTVVAYDLSAQMLDVVAQAAEVRQLKNITTRQGYAE
                     SLPFADNAFDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMDVMSPGHPVRDIWL
                     QTVEALCDTSHVRNYASGEWLRLINEANLIVDNLITDKLPLEFSSWVARMRTPEALVD
                     AIRIYQQSASTEVRTYFALQNDGSFTSDIIMVDAHKAA"
     misc_feature    235426..236010
                     /gene="yafE"
                     /locus_tag="ECs_0206"
                     /note="hypothetical protein; Provisional; Region:
                     PRK08317"
                     /db_xref="CDD:181382"
     misc_feature    235474..235764
                     /gene="yafE"
                     /locus_tag="ECs_0206"
                     /note="Methyltransferase domain; Region: Methyltransf_11;
                     pfam08241"
                     /db_xref="CDD:429883"
     misc_feature    order(235480..235500,235546..235551,235624..235632,
                     235678..235680)
                     /gene="yafE"
                     /locus_tag="ECs_0206"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:100107"
     gene            complement(236148..237506)
                     /gene="mltD"
                     /locus_tag="ECs_0207"
                     /db_xref="GeneID:914041"
     CDS             complement(236148..237506)
                     /gene="mltD"
                     /locus_tag="ECs_0207"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase D"
                     /protein_id="NP_308234.1"
                     /db_xref="GeneID:914041"
                     /translation="MKAKAILLASVLLVGCQSTGNVQQHAQSLSAAGQGEAAKFTSQA
                     RWMDDGTSIAPDGDLWAFIGDELKMGIPENDRIREQKQKYLRNKSYLHDVTLRAEPYM
                     YWIAGQVKKRNMPMELVLLPIVESAFDPHATSGANAAGIWQIIPSTGRNYGLKQTRNY
                     DARRDVVASTTAALNMMQRLNKMFDGDWLLTVAAYNSGEGRVMKAIKTNKARGKSTDF
                     WSLPLPQETKQYVPKMLALSDILKNSKRYGVRLPTTDESRALARVHLSSPVEMAKVAD
                     MAGISVSKLKTFNAGVKGSTLGASGPQYVMVPKKHADQLRESLASGEIAAVQSTLVAD
                     NTPLNSRVYTVRSGDTLSSIASRLGVSTKDLQQWNKLRGSKLKPGQSLTIGAGSSAQR
                     LANNSDSITYRVRKGDSLSSIAKRHGVNIKDVMRWNSDTANLQPGDKLTLFVKNNSMP
                     DS"
     misc_feature    complement(236151..237506)
                     /gene="mltD"
                     /locus_tag="ECs_0207"
                     /note="membrane-bound lytic murein transglycosylase D;
                     Provisional; Region: mltD; PRK10783"
                     /db_xref="CDD:182727"
     gene            complement(237578..238333)
                     /gene="gloB"
                     /locus_tag="ECs_0208"
                     /db_xref="GeneID:914044"
     CDS             complement(237578..238333)
                     /gene="gloB"
                     /locus_tag="ECs_0208"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase"
                     /protein_id="NP_308235.1"
                     /db_xref="GeneID:914044"
                     /translation="MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAIAANNW
                     QPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEF
                     SVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTASQMYQSLKKLSALPDDTL
                     VCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLR
                     TEDIDLINVINEETLLQQPEERFAWLRSKKDRF"
     misc_feature    complement(237581..238333)
                     /gene="gloB"
                     /locus_tag="ECs_0208"
                     /note="hydroxyacylglutathione hydrolase; Provisional;
                     Region: PRK10241"
                     /db_xref="CDD:182327"
     gene            238367..239089
                     /gene="yafS"
                     /locus_tag="ECs_0209"
                     /db_xref="GeneID:914047"
     CDS             238367..239089
                     /gene="yafS"
                     /locus_tag="ECs_0209"
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-L-methionine-dependent
                     methyltransferase"
                     /protein_id="NP_308236.2"
                     /db_xref="GeneID:914047"
                     /translation="MKPARVPQTVVAPDRWGDLPWGELYRKALERQLNPWFTKMYGFY
                     LLKIGNLSAEINCEACAVSHQVNVSAQGMPVQVQADPLHLPFADKSVDVCLLAHTLPW
                     CTDPHRLLREADRVLIDDGWLVISGFNPISLMGLRKLVPVLRKTSPYNSRMFTLMRQL
                     DWLSLLNFEVLHASRFHVLPWNKHGGKLLNAHIPALGCLQLIVARKRTIPLTLNPMKQ
                     SKNKPRIRQAVGATRQCRKPQA"
     misc_feature    <238589..239053
                     /gene="yafS"
                     /locus_tag="ECs_0209"
                     /note="SAM-dependent methyltransferase [Secondary
                     metabolites biosynthesis, transport and catabolism,
                     General function prediction only]; Region: SmtA; COG0500"
                     /db_xref="CDD:223574"
     misc_feature    <238595..238741
                     /gene="yafS"
                     /locus_tag="ECs_0209"
                     /note="Methyltransferase domain; Region: Methyltransf_11;
                     pfam08241"
                     /db_xref="CDD:429883"
     gene            complement(239086..239553)
                     /gene="rnhA"
                     /locus_tag="ECs_0210"
                     /db_xref="GeneID:914053"
     CDS             complement(239086..239553)
                     /gene="rnhA"
                     /locus_tag="ECs_0210"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI"
                     /protein_id="NP_308237.1"
                     /db_xref="GeneID:914053"
                     /translation="MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTN
                     NRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVD
                     LWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV"
     misc_feature    complement(239101..239550)
                     /gene="rnhA"
                     /locus_tag="ECs_0210"
                     /note="ribonuclease H; Reviewed; Region: rnhA; PRK00203"
                     /db_xref="CDD:178927"
     misc_feature    complement(order(239140..239142,239194..239196,
                     239344..239346,239410..239412,239419..239427,
                     239515..239526))
                     /gene="rnhA"
                     /locus_tag="ECs_0210"
                     /note="RNA/DNA hybrid binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:260010"
     gene            239609..240349
                     /gene="dnaQ"
                     /locus_tag="ECs_0211"
                     /db_xref="GeneID:914056"
     CDS             239609..240349
                     /gene="dnaQ"
                     /locus_tag="ECs_0211"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III epsilon subunit DnaQ"
                     /protein_id="NP_308238.2"
                     /db_xref="GeneID:914056"
                     /translation="MTAMSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVVNR
                     RLTGNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPTFAEVADEFMDYIRGAELVIHN
                     AAFDIGFMDYEFSLLKRDIPKTNTFCKVTDSLAVARKMFPGKRNSLDALCARYEIDNS
                     KRTLHGALLDAQILAEVYLAMTGGQTSMAFAMEGETQQQQGEATIQRLVRQASKLRVV
                     FATDEELAAHEARLDLVQKKGGSCLWRA"
     misc_feature    239624..240346
                     /gene="dnaQ"
                     /locus_tag="ECs_0211"
                     /note="DNA polymerase III subunit epsilon; Provisional;
                     Region: PRK05711"
                     /db_xref="CDD:235574"
     misc_feature    order(239651..239662,239666..239671,239798..239803,
                     239810..239815,239909..239914,239918..239926,
                     240047..240052,240092..240094,240101..240103,
                     240116..240118)
                     /gene="dnaQ"
                     /locus_tag="ECs_0211"
                     /note="active site"
                     /db_xref="CDD:99835"
     misc_feature    order(239651..239662,239666..239671,239798..239803,
                     239810..239815,239909..239914,239918..239923,
                     240047..240052,240092..240094,240101..240103,
                     240116..240118)
                     /gene="dnaQ"
                     /locus_tag="ECs_0211"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:99835"
     misc_feature    order(239651..239653,239657..239659,239924..239926,
                     240101..240103,240116..240118)
                     /gene="dnaQ"
                     /locus_tag="ECs_0211"
                     /note="catalytic site [active]"
                     /db_xref="CDD:99835"
     gene            240482..240558
                     /gene="aspV"
                     /locus_tag="ECs_R0027"
                     /db_xref="GeneID:62676010"
     tRNA            240482..240558
                     /gene="aspV"
                     /locus_tag="ECs_R0027"
                     /product="tRNA-Asp"
                     /note="anticodon: gtc"
                     /db_xref="GeneID:62676010"
     gene            240887..241687
                     /gene="yafT"
                     /locus_tag="ECs_5700"
                     /db_xref="GeneID:62676011"
     CDS             240887..241687
                     /gene="yafT"
                     /locus_tag="ECs_5700"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="YP_009502589.1"
                     /db_xref="GeneID:62676011"
                     /translation="MNSKKLCCICVLFSLLAGCASESSIDEKKKKAQVTQSNINKNTP
                     QQLTDKDLFGNETTLAVSEEDIQAALDGDEFRVPLNSPVILVQSGNRAPETIMQEEMR
                     KYYTVSTFSGIPDRQKPLTCNKNKDKNENEDVARAENMNWMQALRFVAAKGHQKAIIV
                     YQDMLQTGKYDSALKSTVWSDYKNEKLTDAISLRYLVRFTLVDVATGEWATWSPVNYE
                     SRVIFPPAGITKTSNKELSNDHVTEAQLFNLKQKTYVSMVKDLVSRFQ"
     gene            complement(241872..242168)
                     /locus_tag="ECs_0212"
                     /db_xref="GeneID:914062"
     CDS             complement(241872..242168)
                     /locus_tag="ECs_0212"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308239.1"
                     /db_xref="GeneID:914062"
                     /translation="MIIINLRLTLLFILATFTYSVQSDEFDDQTTYTQYRYFSTAIPE
                     DIRRFMFYVDYCFVDLAFDIETDSMTAKNDIINECTPLKERNKTLKEKYKKMKR"
     gene            complement(242165..242614)
                     /locus_tag="ECs_0213"
                     /db_xref="GeneID:914064"
     CDS             complement(242165..242614)
                     /locus_tag="ECs_0213"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308240.1"
                     /db_xref="GeneID:914064"
                     /translation="MRKITIILLLTFSCTKGLAFDISMSKECSGVDELEFIDCVKNSF
                     IMSTITLKKAEANIKEKIQKWNSDEDEAIRKEAVISLKRLESSNREFIRYRFAQCSFT
                     LTWGARVGRLAFSRLYPCYTELNKIRAMQLNNAYISDFQNPDEISSK"
     gene            complement(242617..243213)
                     /locus_tag="ECs_0214"
                     /db_xref="GeneID:914067"
     CDS             complement(242617..243213)
                     /locus_tag="ECs_0214"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308241.2"
                     /db_xref="GeneID:914067"
                     /translation="MLWTENDAENTSQWNGYPLQIGRFRKDKAMPALISGEKSTALVT
                     PPQWRNKAFNGLKDPERNYWAKEQITGSPEENIKAAITYLMMKLSNTKEESTIDQYDS
                     TLYSAIVQKGDLADNIRKERKTTIPNLTKNNPGKNLDKIHPGDILYYQKASMKVIITG
                     WKPITIKNVAMNYNGGGDPKYAIKLQFVYTLLTKNRVL"
     gene            complement(243292..243513)
                     /locus_tag="ECs_0215"
                     /db_xref="GeneID:62676012"
     CDS             complement(243292..243513)
                     /locus_tag="ECs_0215"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_302948.1"
                     /db_xref="GeneID:62676012"
                     /translation="MANNILHSSTSDSESKNTSTDSTLFNEKFPFQLRQDFASRITED
                     ESDFFKWKKIRELAFVSNHKEWNKYDLLI"
     gene            complement(243534..244013)
                     /locus_tag="ECs_0216"
                     /db_xref="GeneID:914071"
     CDS             complement(243534..244013)
                     /locus_tag="ECs_0216"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system effector Hcp1 family
                     protein"
                     /protein_id="NP_308243.1"
                     /db_xref="GeneID:914071"
                     /translation="MANLIYLTLNGDNQGLISSGCSSQPSIGNKAQTAHIDQIMIYEF
                     MHGLNRDQNVNHHHLTIKKPIDKASPLLGKAICDNELLTCDFSFYRTNKFGINELFYK
                     IKLTGAKISDIHVSISHIVVDNSVQPEESVSFSYESIIWEHCSAGTSAYSLWEDRLF"
     misc_feature    complement(243543..244010)
                     /locus_tag="ECs_0216"
                     /note="type VI secretion system effector, Hcp1 family;
                     Region: VI_effect_Hcp1; TIGR03344"
                     /db_xref="CDD:213799"
     gene            complement(243979..245388)
                     /locus_tag="ECs_0217"
                     /db_xref="GeneID:914077"
     CDS             complement(243979..245388)
                     /locus_tag="ECs_0217"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308244.1"
                     /db_xref="GeneID:914077"
                     /translation="MNSNVLTQTIVTGSDPRGLPEFSAIREEINKASHPSQPELNWKL
                     VESLALAIFKANGVDLHTATYYTLARTRTQGLAGFCEGAELLAAMVSHDWDKFWPQGG
                     PARTEMLDWFNSRTGNILRQQISFAESDLPLIYRTERALQLICDKLQQVELKRVPRVE
                     NLLYFMQNTRKRLEPQLKSNTENAAQTTVRTLIYAPETQASSTPEAVVPPLPGLPEMK
                     VEVRSLTENPPQASVIKQGSTVRGFIAGIACSVAVASALWWWQVYPVQQQLLQVNDTA
                     QGAATVWMASPELENYERRLQQLLDTSPVQPLETGMQMMRVADSRWPESLQQQQASTQ
                     WNEALKTRAQSSPQLRGWLQTRQDLHAFADLVMQREKEGLTLSYIKNVIWQAERGLGQ
                     ETPVESLLTQYQDARAQKQNTDALEKQINERLEGVLSRWLLLKNNTIPTIKKALNFNN
                     IHEYKGVLNGEFNLFNTKW"
     misc_feature    complement(244378..245388)
                     /locus_tag="ECs_0217"
                     /note="Predicted component of the type VI protein
                     secretion system [Intracellular trafficking, secretion,
                     and vesicular transport]; Region: COG3515"
                     /db_xref="CDD:226046"
     misc_feature    complement(244084..244515)
                     /locus_tag="ECs_0217"
                     /note="Type VI secretion system, EvfB, or VasL; Region:
                     VasL; pfam12486"
                     /db_xref="CDD:432588"
     gene            complement(245399..248833)
                     /gene="impL"
                     /locus_tag="ECs_0218"
                     /db_xref="GeneID:914079"
     CDS             complement(245399..248833)
                     /gene="impL"
                     /locus_tag="ECs_0218"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein ImpL"
                     /protein_id="NP_308245.2"
                     /db_xref="GeneID:914079"
                     /translation="MLILAWIFLLVWIWWKGPTWTLYEEQWLKPLANRWLATAAWGII
                     ALVWLTVRVMKRLQLLEKQQKQQREEAIDPLSVELNAQQRYLDRWLLRLQRHLDNRRF
                     LWQLPWYMVIGPAGSGKTTLLREGFPSDIIYAPEGARGTEQRLYLTPHVGKQAVIFDI
                     DGTLCAPADADILHRRLWEHALGWLKEKRARQPLNGIILTLDLPDLLTADKRHREHLL
                     QTLRSRLQDIRQHLHCQLPVYVVLTRLDLLQGFAALFQSLNRQDRDAILGVTFTRRAH
                     ENDDWRTELNAFWQTWVDRMNLALPDLMVTQTHTRASLFSFSRQMQGSREPLVSLLEG
                     LLDGENMNVMLRGVYLTSSLQRGQMDDIFTQSAARQYRLGNNPLASWPLVDTAPYFTR
                     SLFPQALLAEPNLATESRAWLMRSRRRLTVFSATGGVAALLLITGWHHYYNGNYQSGI
                     TVLKQAKAFMDVPPPQGEDDYGNLQLPLLNPVRDATLAYGDWGDRSRLADMGLYQGRR
                     IGPYVEQTYLQLLEQRYLPSLFNGLVKAMNAAPPESEEKLAVLRVMRMLEDKSGRNNE
                     VVKQYMAKRWSEKFHGQRDIQAQLMSHLDYALAHTDWHAERQAGDGDAISRWTPYDKP
                     VVSAQKELSKLPVYQRVYQSLKTRALGVLPADLNLRDQVGPTFDQVFTSADDNKLVVP
                     QFLTRYGLQSYFVKQRDELVELTAMDSWVLNLTRSVKYSDADRAEIQRQLTEQYISDY
                     TATWRAGMDNLNIRNFESIGQLTGALEQVISGDQPLQRALTVLRDNTQPGVFSEKLSA
                     KERDEALAEPDYQLLTRLGHEFAPENITLAVQKDKESTMQAVYQQLTELHRYLLAIQN
                     APVPGKSALKAVQLRLDQNSSDPIFATRQMAKTLPAPLNRWVGRLTDQAWHVVMVEAV
                     HYMEVDWRDSVVKPFNEQLANNYPFNPRSAQDASLDAFERFFKPDGILDTFYQQNLKL
                     FIDNDLSLEDGDNNVIIREDIIAQLETAQKIRDIFFSKQNGLGTSFAVETVSLSGNKR
                     RSVLNLDGQLVDYSQGRNYTAHLVWPNNMREGNESKLTLIGTSGNAPRSISFSGPWAQ
                     FRLFGAGQLTGVQDGNFTVRFSVDGGAMTYRVHTDTEDNPFSGGLFSQFGLSDTLY"
     misc_feature    complement(245402..248833)
                     /gene="impL"
                     /locus_tag="ECs_0218"
                     /note="Type VI protein secretion system component VasK
                     [Intracellular trafficking, secretion, and vesicular
                     transport]; Region: IcmF; COG3523"
                     /db_xref="CDD:226054"
     gene            complement(248970..250381)
                     /locus_tag="ECs_0219"
                     /pseudogene="unknown"
                     /db_xref="GeneID:62676013"
     misc_feature    complement(248970..250381)
                     /locus_tag="ECs_0219"
                     /note="hypothetical protein"
                     /pseudogene="unknown"
     gene            complement(250386..251129)
                     /locus_tag="ECs_0222"
                     /db_xref="GeneID:914092"
     CDS             complement(250386..251129)
                     /locus_tag="ECs_0222"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein"
                     /protein_id="NP_308249.1"
                     /db_xref="GeneID:914092"
                     /translation="MSRLRVFRQTGWFIAGLMTGLPATAAPAEASSMAGVAVAVATTT
                     PPDATATLQAMQSCRRESAALERLDCYDHLLAPLSPSGFDGALVKAGFVGEAWTRATE
                     QEKRREGNTTELLVTQVPGERPTVVITTPAIGHVPPRPVLMFSCVDNITRMQVALMHP
                     LDVHDIAVTLNADSRALRSHWFVRENGTLLESSRGLSGIDEIKQLFGAKTLTVDTGAD
                     NAAGKLTFNIDGLARAIAPLRDACHWAGE"
     misc_feature    complement(250398..250970)
                     /locus_tag="ECs_0222"
                     /note="type VI secretion-associated protein, VC_A0118
                     family; Region: VI_minor_1; TIGR03360"
                     /db_xref="CDD:132403"
     gene            complement(251126..253897)
                     /locus_tag="ECs_0223"
                     /db_xref="GeneID:914094"
     CDS             complement(251126..253897)
                     /locus_tag="ECs_0223"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp proteinase"
                     /protein_id="NP_308250.1"
                     /db_xref="GeneID:914094"
                     /translation="MIQIDLPTLVKRLNLFSRQALEMAASECMSQQAAEITVSHVLIQ
                     MLAMPRSDLRVITRQGDIGMEELRQALTVENYTTARSADSYPAFSPMLVEWLKEGWLL
                     ASAEMQHSELRGGVLLLALLHSPLRYIPPAAARLLTGINRDRLQQDFVQWTQESAESV
                     VPDADGKGAGTLTDASDTLLARYAKNMTEDARNGRLAPVLCRDHEIDLMIDILCRRRK
                     NNPVVVGEAGVGKSALIEGLALRIVAGQVPDKLKNTDIMTLDLGALQAGASVKGEFEK
                     RFKGLMAEVISSPVPVILFIDEAHTLIGAGNQQGGLDISNLLKPALARGELKTIAATT
                     WSEYKKYFEKDAALSRRFQLVKVSEPNAAEATIILRGLSAVYERSHGVLIDDDALQAA
                     ATLSERYLSGRQLPDKAIDVLDTACARVAINLSSPPKQISALTTLSHQQEAEIRQLER
                     ELRIGLRTDTSRMTEVLVQYDETLTALDELEAAWHQQQTLVREIIALRQQLLGVAEDD
                     AAPLPDADTVEDTQPESESESEQDNTGAVPADETDREQPEETAETVSPVQRLAQLTAE
                     LDALHNDRLLVSPHVDKKQIAAVIAEWTGVPLNRLSQNEMSVITDLPKWLGDTIKGQD
                     LAIASLHKHLLTARADLRRPGRPLGAFLLAGPSGVGKTETVLQLAELLYGGRQYLTTI
                     NMSEFQEKHTVSRLIGSPPGYVGYGEGGVLTEAIRQKPYSVVLLDEVEKAHPDVLNLF
                     YQAFDKGEMADGEGRLIDCKNIVFFLTSNLGYQVIVEHADDPETMQEALYPVLADFFK
                     PALLARMEVVPYLPLSKETLATIIAGKLARLDNVLRSRFGAEVVIEPEVTDEIMSRVT
                     RAENGARMLESVIDGDMLPPLSLLLLQKMAANTAIARIRLSAVDGAFTADVEDAQNDE
                     SVTKDETVL"
     misc_feature    complement(251204..253861)
                     /locus_tag="ECs_0223"
                     /note="type VI secretion ATPase, ClpV1 family; Region:
                     VI_ClpV1; TIGR03345"
                     /db_xref="CDD:274528"
     gene            complement(253906..254667)
                     /gene="impK"
                     /locus_tag="ECs_0224"
                     /db_xref="GeneID:914096"
     CDS             complement(253906..254667)
                     /gene="impK"
                     /locus_tag="ECs_0224"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein ImpK"
                     /protein_id="NP_308251.1"
                     /db_xref="GeneID:914096"
                     /translation="MDEGSLSLPPFTGYDEKSLRDYHLALHGNSLNPMIDAATPLLGM
                     VMRLSTMNSQTMPEHLFAQVVTDVQAVEQLLQEQGYEPGVIISFRYILCTFIDEAALG
                     NGWSNKNEWIKQSLLVHFHNEAWGGEKVFILLERLIREPKRYQDLLEFLWLCFSLGFR
                     GRYKVAVQDQGEFEQIYRRLYHVLHKLRGDAPFPLLHQDKKTQGGRYQLISRLTVKHI
                     FCGGVVVLALFYLFYLLRLDSQTQDILHQLNKLLR"
     misc_feature    complement(253909..254667)
                     /gene="impK"
                     /locus_tag="ECs_0224"
                     /note="Type VI protein secretion system component VasF
                     [Intracellular trafficking, secretion, and vesicular
                     transport]; Region: COG3455"
                     /db_xref="CDD:225986"
     gene            complement(254672..256003)
                     /gene="impJ"
                     /locus_tag="ECs_0225"
                     /db_xref="GeneID:914109"
     CDS             complement(254672..256003)
                     /gene="impJ"
                     /locus_tag="ECs_0225"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein ImpJ"
                     /protein_id="NP_308252.1"
                     /db_xref="GeneID:914109"
                     /translation="MATTRNKVMWQEGMLMRPHHFQQQQRYNDYLDNQRFRAMNDLSW
                     GFTELTLNNELLAQGKIMIDSASGTLPDGTVFSIPDQDALPDPLHPQNFPDERSRNIY
                     LALPVASDVRNEISDGRRIGRYRLNYADVRDLHSEEGDARTLTLGQLTPRIMSGAEDM
                     SAYITLPLCRISDRHADGSLTLDDDFIPSCQNIQVSKKLRVYLKEVQGAIGGRASDLA
                     NRIGSPAQSGIADVAEFMMLQLLNRNQTRFTHRARRSQLHPEDFYLDLAELLGELMTF
                     TEPSRLPCPLDVYDHHDLTKTFKTLLPEVKRALHTVLSPRAVNLPLHLRDGIWQADVH
                     DSELLQSATFVLAVAANMPVDQIQRQFIQQSKISSPEKIRNMVSVQIPGIPLRALMVA
                     PRQLPYHSGFSYFELDKSGQAWTEMAAAGAVALHVSGSFPDLNMQLWAIRG"
     misc_feature    complement(254675..256000)
                     /gene="impJ"
                     /locus_tag="ECs_0225"
                     /note="Predicted component of the type VI protein
                     secretion system [Intracellular trafficking, secretion,
                     and vesicular transport]; Region: COG3522"
                     /db_xref="CDD:226053"
     gene            complement(256006..256530)
                     /locus_tag="ECs_0226"
                     /db_xref="GeneID:914114"
     CDS             complement(256006..256530)
                     /locus_tag="ECs_0226"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="NP_308253.1"
                     /db_xref="GeneID:914114"
                     /translation="MNRKAFLACVLMCVILTGCETAKKISEVIKNPDIQVGSLKEQPS
                     EITVTLLTEPDTNTNAEGESAAVDVQLVYLTDDSKLQAADYDQIASTPLPDVLGKNYI
                     DHQDFNLLPDTIKTLPPIKLDEKTQFIGVVAYFSDDQATEWKQIETVEGTGHHYRLLV
                     HVRQSSIEMKKEDE"
     misc_feature    complement(256009..256530)
                     /locus_tag="ECs_0226"
                     /note="Predicted component of the type VI protein
                     secretion system [Intracellular trafficking, secretion,
                     and vesicular transport]; Region: COG3521"
                     /db_xref="CDD:226052"
     gene            complement(256527..257807)
                     /gene="imp"
                     /locus_tag="ECs_0227"
                     /db_xref="GeneID:914116"
     CDS             complement(256527..257807)
                     /gene="imp"
                     /locus_tag="ECs_0227"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein ImpI"
                     /protein_id="NP_308254.1"
                     /db_xref="GeneID:914116"
                     /translation="MPEEKLQTLSLQVINGSELESGRAARCLFTQQGNVGHAPECHWS
                     VQDRQQSIPAQAFTVILHDGTFCLRPQTAQLWLNQAKVTATSDLIQLRQGDEIQIGRL
                     MVRVHLNRGDIPHYDEEMATPETIVTNRDMLTDTLLSTEGAPHYPGMTHRHQLADTVV
                     NGFSADPLQALQSESLITTGDPLSGIAAVRPSAPLSDPASNGGINTPFMDLPPIYASP
                     GDHNDDISAAEMAQRHLAVTPLLRGLGGSLTVSNSDDADDFLEEAGRTLQAAIKGLLD
                     LQQQRNSLSDKHLRPLEDNPLRLNMDYATALDVMFAEGKSPVHLAAPAAVSESLRNVR
                     HHEEANRAAIVESLRVLLDAFSPQNLLRRFVQYRRSHELRQPLDDAGAWQMYSHYYEE
                     LASDRQQGFEMLFNEVYAQVYDRVLREKQREPEA"
     misc_feature    complement(256539..257789)
                     /gene="imp"
                     /locus_tag="ECs_0227"
                     /note="Predicted component of the type VI protein
                     secretion system, contains a FHA domain [Signal
                     transduction mechanisms, Intracellular trafficking,
                     secretion, and vesicular transport]; Region: COG3456"
                     /db_xref="CDD:225987"
     gene            complement(257832..258914)
                     /gene="impH"
                     /locus_tag="ECs_0228"
                     /db_xref="GeneID:914121"
     CDS             complement(257832..258914)
                     /gene="impH"
                     /locus_tag="ECs_0228"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein ImpH"
                     /protein_id="NP_308255.1"
                     /db_xref="GeneID:914121"
                     /translation="MDGKNRAASSYLSPGNPPADKEQNDPLAQVFHNACSYNFFAMAE
                     LLHRLAKGEKGTPELSLRDDPAQETLRFSADASLAFPCSDISALKRDTSGAFRMTTTF
                     MGLQGSQSPLPGYYLDHLAWKAVHEQSPVGDFLDMFSHRLTQFVWHIWRKYRYHISFR
                     NGGVDAFSQRMYSLVGLGHRQLRDKLAINHSKMLAYSGILANPGRSPEIICGLVSHCF
                     DLSEVTLQNWQRRKVDIEPDQQNSLGSYSLKNGEKLAGRSVLGNFVLGTRVPDLSGKF
                     QLSITSLTRKQFLSFLPSGENFLPLTTFVSFILRDQLAWDLHLGLAPEQVGAMRLGDN
                     KSALLGWTSFLGTPEERPSVTIRVRS"
     misc_feature    complement(257838..258869)
                     /gene="impH"
                     /locus_tag="ECs_0228"
                     /note="Predicted component of the type VI protein
                     secretion system [Intracellular trafficking, secretion,
                     and vesicular transport]; Region: COG3520"
                     /db_xref="CDD:226051"
     gene            complement(258878..260728)
                     /locus_tag="ECs_0229"
                     /db_xref="GeneID:914124"
     CDS             complement(258878..260728)
                     /locus_tag="ECs_0229"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein"
                     /protein_id="NP_308256.1"
                     /db_xref="GeneID:914124"
                     /translation="MEFEERYFREELDYLRQLSKLLATEKPHLARFLAEKDADPDIER
                     LLEGVAFLTGNLRQKIEDEFPELTHGLIKMLWPNYLRPVPAMTLIEYTPDMDKSSVPV
                     LIPRNEQFTTNAGEIRVDEVLPSDAKKEEPPPCTFTLCRDIWLLPVRLEQIENRSTTR
                     NGVINITFSVAPGTDFRTLDLNKLRFWLGNDDNYTRDQLYLWFCEYLQGADLTVGEQH
                     IRLPEFMLKAVGFEPQDAMLPWPKNVHSGYRILQEYFCYPDAFLFFDLCGCPALPDGL
                     QAEFFTLQLRFSRPLPVDIRLRRDSLRLYCAPAINLFIHHAEAITLDNRRADYPLVPS
                     RHYPQHYDVFSVNSVVSQVQDMFRKKDLGRPVSTQAARQWPAFESFSHQMEYSRKREV
                     VYWHHRTKTSLFHRGFDHTLAFIHADGSYPSDESLLSNEVVSVSLTCTNRELPSQIRS
                     GDITGTTGKNAAVASFRNITRPTQPLWPVIDGSLHWSLLSAMNLNYLSLLDTDALKQV
                     IANFDRHAIHHPQTARLSQQKLDAIERLETRPVDRLFTGIPVRGLASTLYLHPEPFVC
                     EGEMYLLGTVLSHFLSLYASVNSFHMLTVVNTESQETWKWTERIGQHPLI"
     misc_feature    complement(258881..260695)
                     /locus_tag="ECs_0229"
                     /note="Type VI protein secretion system component VasA
                     [Intracellular trafficking, secretion, and vesicular
                     transport]; Region: COG3519"
                     /db_xref="CDD:226050"
     gene            complement(260732..261145)
                     /locus_tag="ECs_0230"
                     /db_xref="GeneID:914125"
     CDS             complement(260732..261145)
                     /locus_tag="ECs_0230"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein"
                     /protein_id="NP_308257.1"
                     /db_xref="GeneID:914125"
                     /translation="MILDRERTTGSLFERMEASSARNRQGGSIHSLRQSIRQNLRNIL
                     NTRSGSCRGAPELGIDEPEGAENFRESMSRAIEQCIERYEPRISHAEVQAVVSSASSP
                     LDMTFHITAWVTFNETHEVLEFDMAPNGSQHYRVD"
     misc_feature    complement(260738..261121)
                     /locus_tag="ECs_0230"
                     /note="type VI secretion system lysozyme-like protein;
                     Region: VI_zyme; TIGR03357"
                     /db_xref="CDD:274540"
     gene            complement(261236..262627)
                     /gene="impC"
                     /locus_tag="ECs_0231"
                     /db_xref="GeneID:914127"
     CDS             complement(261236..262627)
                     /gene="impC"
                     /locus_tag="ECs_0231"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein ImpC"
                     /protein_id="NP_308258.1"
                     /db_xref="GeneID:914127"
                     /translation="MSLQEEELVSSHAGQPEQESSLLDQIMAQTRIQPGSEGYDVARQ
                     GVTAFIASILQSTASAEPVNKLAVDSMIADIDERISRQMDVIIHAPAFQQVESFWRSL
                     KTMVDRVDFRENIKVNVLHVTKQELLEDFEFAPEIIQSGFYKHVYSSGFGQFGGEPIA
                     AVLGAYEFKNTAPDMKLLQYVSAVGAMAHAPFLSSVSPEFMGLNSWTELPNIKDLYAI
                     FEGPAYTKWRALRDSEDSRYLGLTAPRFLLRQPYSPTDNPVKNFNYYEDVSQNHEDYL
                     WGNTAWMLACNIADSFAKYRWCPNIIGPQSGGAVKDLPVHLFETMGQIQAKIPTEVLV
                     TDRREFELAEEGFITLTMRKDSDNAAFFSANSVQKPKHFPGKDAETNYKLGTQLPYLF
                     IINRLAHYIKVLQREQLGSWKERSDLERELNTWIRQYVADQENPPADVRSRKPLRAAK
                     VEVMDVEGEPGWY"
     misc_feature    complement(261239..262621)
                     /gene="impC"
                     /locus_tag="ECs_0231"
                     /note="Predicted component of the type VI protein
                     secretion system [Intracellular trafficking, secretion,
                     and vesicular transport]; Region: COG3517"
                     /db_xref="CDD:226048"
     gene            complement(262678..262902)
                     /locus_tag="ECs_0232"
                     /db_xref="GeneID:914129"
     CDS             complement(262678..262902)
                     /locus_tag="ECs_0232"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308259.1"
                     /db_xref="GeneID:914129"
                     /translation="MTAHKNISGTYHLSVADILQVVYQVCFSPSVEINQDGVAALITT
                     LDRRISDLLDEIIHFCEFQQSASHWQRVLH"
     misc_feature    complement(<262681..262860)
                     /locus_tag="ECs_0232"
                     /note="Predicted component of the type VI protein
                     secretion system [Intracellular trafficking, secretion,
                     and vesicular transport]; Region: COG3517"
                     /db_xref="CDD:226048"
     gene            complement(262937..263437)
                     /gene="impB"
                     /locus_tag="ECs_0233"
                     /db_xref="GeneID:914131"
     CDS             complement(262937..263437)
                     /gene="impB"
                     /locus_tag="ECs_0233"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein ImpB"
                     /protein_id="NP_308260.1"
                     /db_xref="GeneID:914131"
                     /translation="MSKKFEGSVAPRERINISYVPKTDGQTAEVELPLNMLVVGDTGN
                     TQETSSLDERQAVSVNKHNFGAVMAEAAIGLNFTVPATLKGSTTDDEMNVALNIKSLD
                     DFSPDSVARQVPEVNKLLELREALTALKGPMGNLPAFRTQLQALLENEESREQLLKEI
                     GQVSNK"
     misc_feature    complement(262940..263437)
                     /gene="impB"
                     /locus_tag="ECs_0233"
                     /note="Predicted component of the type VI protein
                     secretion system [Intracellular trafficking, secretion,
                     and vesicular transport]; Region: COG3516"
                     /db_xref="CDD:226047"
     gene            264134..264652
                     /locus_tag="ECs_0234"
                     /db_xref="GeneID:914133"
     CDS             264134..264652
                     /locus_tag="ECs_0234"
                     /codon_start=1
                     /transl_table=11
                     /product="Hcp-like protein"
                     /protein_id="NP_308261.1"
                     /db_xref="GeneID:914133"
                     /translation="MPTPCYISITGQTQGNITAGAFTADSVGNIYVQGHEDEMLVQEF
                     LHNVTVPTDPQSGQPAGQRAHKPFIFTVALNKAVPLMYNALASGEMLPTTELHWWRTS
                     VEGKQEHYFTTRLTDSTIVDMKLHMPHCQDPAKREFTQLLEVSLAYRKIEWEHVKSGT
                     SGADDWRAPLEA"
     misc_feature    264137..264640
                     /locus_tag="ECs_0234"
                     /note="type VI secretion system effector, Hcp1 family;
                     Region: VI_effect_Hcp1; TIGR03344"
                     /db_xref="CDD:213799"
     gene            264862..267003
                     /gene="vgrE"
                     /locus_tag="ECs_0236"
                     /db_xref="GeneID:914167"
     CDS             264862..267003
                     /gene="vgrE"
                     /locus_tag="ECs_0236"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system Vgr family protein"
                     /protein_id="NP_308263.1"
                     /db_xref="GeneID:914167"
                     /translation="MSTGLRFTLEVDGLPPDAFAVVFFHLNQSLSSLFSLALSLVSQQ
                     FLSLEFQQILDKMAYLTIWQGDDVQRRVKGVVTWFELGENDKNQKLYSMKVCPPLWRT
                     GLRQNFRIFQNEDIASILGTILQENGVTEWSPLFSEPHPSREFCVQYGETDYDFLCRM
                     AAEEGIFFYEEHAQKSTDQSLVLCDTVLYLPESFEIPWNPNTRTEVSTLCISQFRYSA
                     QIRPSSVVTKDYTFKRPGWAGRFDQEGQHQDYQRTQYEVYDYPGRFKGAHGQNFARWQ
                     MDGWRNNAEVARGTSRSPEIWPGRRIVLTGHPQANLNREWQVVASELHGEQPQAVPGR
                     RGSGTTLDNHFAVIPADRTWRPQPLLKPLVDGPQSAVVTGPAGEEIFCDEHGRVRVKF
                     NWDRYNPSNQDSSCWIRVAQAWAGTGFGNLAIPRVGQEVIVDFLNGDPDQPIIMGRTY
                     HQENRTPGSLPGTKTQMTIRSKTYKGSGFNELKFDDATGKEQVYIHAQKNMNTEVLNN
                     RTTDVINNHAEKIGNNQAITVTNNQILNIGVNQIQTVGVNQVETVGSNQIIKVGSNQV
                     EKVGIIRALTVGVAYQTTVGGIMNTSVALLQSSQVGLHKSLMVGMGYSVNVGNNVTFS
                     VGKTMKENTGQTAVYSAGEHLELCCGKARLVLTKDGSIFLNGTHIHLEGESDVNGDAP
                     VINWNCGATQPVPDAPVPKDLPPGMPDMRQF"
     misc_feature    264880..266415
                     /gene="vgrE"
                     /locus_tag="ECs_0236"
                     /note="type VI secretion system Vgr family protein;
                     Region: VI_Rhs_Vgr; TIGR03361"
                     /db_xref="CDD:274542"
     gene            267079..271293
                     /gene="rhsC"
                     /locus_tag="ECs_0237"
                     /db_xref="GeneID:914169"
     CDS             267079..271293
                     /gene="rhsC"
                     /locus_tag="ECs_0237"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion protein Rhs"
                     /protein_id="NP_308264.2"
                     /db_xref="GeneID:914169"
                     /translation="MGGKPAARQGDMTRKGLDIVQGSAGVLIGAPTGVACSVCPGGIT
                     YANPVNPVLGAKVLPGETDLALPGPLPFILSRAYSSYRTRTPAPVGVFGPGWKAPFDI
                     RLQIRDEGLILNDNGGRSIHFEPLFPGEISYSRSESFWLARGGVAEQHSSQPLSALWQ
                     VLPEDVRLSPHMYLATNSLQGPWWILNWPERVPGADEVLPPEPPAYRVLTGVVDGFGR
                     TLAFHRAAEGDVAGAVTGVTDGAGRRFHLVLTTQAQRAEVFRKQRATSLSSPAGPRSA
                     SSSLVFPDTLPAGTEYGADNGIRLEAVWLTHDPAYPDELPAAPLARYTYTASGELRAV
                     YDRSGTQVRGFAYDAEHAGRMVAHHYAGRPESRYRYDDTGRVTELVNPEGLDYRFEYG
                     QDRVTITDSLNRREVLYTEGEGGLKRVVKKEHADGSITRSEYDEAGRLKAQTDAAGRR
                     TEYSLHMASGAVTAVTGPDGRTVRYGYNSQRQVTSVTYPDGLRSSREYDEKGRLAAET
                     SRSGETTRYSYDDPASELPTGIQDATGSTKQMAWSRYGQLLTFTDCSGYTTRYEYDRY
                     GQQIAVHREEGISTYSSYNPRGQLVSQKDAQGRETRYEYSAAGDLTAIVAPDGSRSEI
                     QYDAWGKAVSTTQGGLTRSMGYDAAGRITVLTNENGSQSTFRYDPVDRLTEQRGFDGR
                     TQRYHYDLTGKLTQSEDEGLVTLWHYDASDRITHRTVNGDPAEQWQYDEHGWLTTLSH
                     TSEGHRVSVHYGYDDKGRLTGERQTVENPETGEMLWEHETGHAYSEQGLATRQEPDGL
                     PPVEWLTYGSGYLAGMKLGGTPLVEYMRDRLHRETARSFGGEAYELATAWNTSGQLRS
                     RHLNLPQLDRDYDWNDNGQLIRISGPQESREYRYSDTGRLTGVHTTAANLDIDIPYAT
                     DPAGNRLPDPELHPDSTLTAWPDNRIAEDAHYVYRYDEYGRLAEKTDRIPEGVIRMHD
                     ERTHHYHYDSQHRLVFHTRIQHGEPQVESRYLYDPLGRRTGKRVWRRERDLTGWMSLS
                     RKPEETWYGWDGDRLTTVQTQQTRIQTVYQPGSFTPLLRIETENGEQAKARHRSLAEV
                     LQEDTGVTLPAELAVMLGRLERELRQGSVSEESQQWLAQCGLTAEQMAAQLEAEYIPE
                     RKLHLYHCDHRGLPLALISPEGETAWQGEYDEWGNLLGETSAQHLQQSLRLPGQQYDE
                     ESGLYYNRNRYYDPLQGRYITQDPIGLEGGWNLYQYPLNPIEHIDPLGLALDLNYYSP
                     SDPIYKGSLNVREFPTGFTVGGHGSPTSMSDDRIKKGSDLTIKQLASDIRANPKYHEG
                     MPVVLFSCETGKGKNSFAQKLANELDATVIAPDEIIWIWPDGNYAIMGQTARITIGGK
                     DNGVFELVPDEKQPGDFHKFTPTGSK"
     misc_feature    <267079..267165
                     /gene="rhsC"
                     /locus_tag="ECs_0237"
                     /note="proline-alanine-alanine-arginine (PAAR) repeat
                     superfamily; Region: PAAR_like; cl21497"
                     /db_xref="CDD:451275"
     misc_feature    267217..267447
                     /gene="rhsC"
                     /locus_tag="ECs_0237"
                     /note="Domain of unknown function (DUF6531); Region:
                     DUF6531; pfam20148"
                     /db_xref="CDD:437980"
     misc_feature    <267691..268968
                     /gene="rhsC"
                     /locus_tag="ECs_0237"
                     /note="Uncharacterized conserved protein RhsA, contains 28
                     RHS repeats [General function prediction only]; Region:
                     RhsA; COG3209"
                     /db_xref="CDD:225750"
     misc_feature    268711..271290
                     /gene="rhsC"
                     /locus_tag="ECs_0237"
                     /note="Uncharacterized conserved protein RhsA, contains 28
                     RHS repeats [General function prediction only]; Region:
                     RhsA; COG3209"
                     /db_xref="CDD:225750"
     gene            271362..271907
                     /gene="yibG"
                     /locus_tag="ECs_0238"
                     /db_xref="GeneID:914172"
     CDS             271362..271907
                     /gene="yibG"
                     /locus_tag="ECs_0238"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308265.2"
                     /db_xref="GeneID:914172"
                     /translation="MDNSKHSDEAEKLLAELSARKGEGEGEGEGEGEGEGEGEPKSTV
                     SVFYLQPEEVNTLSHQAKRGDGEAGFRLFLYYKLSNYDEEKSSQWLKIAANNGHATAQ
                     YRLYVELQEQGETKEANEWLQKIKLAASNNDSSAIWFLVNCYKNQGNKKEALQWAYKL
                     KASKQPLDADRLIEELTKEQK"
     misc_feature    <271539..>271868
                     /gene="yibG"
                     /locus_tag="ECs_0238"
                     /note="TPR repeat [Signal transduction mechanisms];
                     Region: TPR; COG0790"
                     /db_xref="CDD:223861"
     misc_feature    271605..271691
                     /gene="yibG"
                     /locus_tag="ECs_0238"
                     /note="SLR repeat [structural motif]; Region: SLR repeat"
                     /db_xref="CDD:276807"
     misc_feature    271710..271799
                     /gene="yibG"
                     /locus_tag="ECs_0238"
                     /note="SLR repeat [structural motif]; Region: SLR repeat"
                     /db_xref="CDD:276807"
     repeat_region   272534..273799
                     /note="ISEc1 Family: ISAs1 partial"
     gene            272653..273789
                     /gene="ydcC"
                     /locus_tag="ECs_0241"
                     /db_xref="GeneID:914217"
     CDS             272653..273789
                     /gene="ydcC"
                     /locus_tag="ECs_0241"
                     /codon_start=1
                     /transl_table=11
                     /product="H repeat-associated protein"
                     /protein_id="NP_308268.1"
                     /db_xref="GeneID:914217"
                     /translation="MELKKLMEHISIIPDYRQAWKVEHKLSDILLLTICAVISGAEGW
                     EDIEDFGETHLDFLRQYGDFENAIPVHDTIARVVSCISPAKFHECFINWMRDCHSSDD
                     KDVIAIDGKTLRHSYDKSRRRGAIHVISAFSTMHSLVIGQIKTDEKSNEITAPPELLN
                     ILDIKGKIITTDAMGCQKDIAEKIQKQGGDYLFAVKGNQGRLNKAFEEKFPLKELNNP
                     EHDSYAISEKSHGREEIRLHIVCEVPDELIDFTFEWKGLKKLCVAVSFRSIIAEQKKE
                     PKMTVRYYISSADLTAGKFATAIRNHWHVENKLHWRLDVVMNEDDCKIRRGNAAELFS
                     GIRHIAINILTNDKVFKAGLRRKMRKAAMDRNYLASVLAGSGLS"
     misc_feature    272737..273684
                     /gene="ydcC"
                     /locus_tag="ECs_0241"
                     /note="ISAs1 family transposase; Region: transpos_ISAs1;
                     NF033564"
                     /db_xref="CDD:411194"
     misc_feature    273601..>273786
                     /gene="ydcC"
                     /locus_tag="ECs_0241"
                     /note="Predicted transposase YbfD/YdcC associated with H
                     repeats [Mobilome: prophages, transposons]; Region: YhhI;
                     COG5433"
                     /db_xref="CDD:227720"
     gene            273792..275552
                     /locus_tag="ECs_0242"
                     /db_xref="GeneID:914218"
     CDS             273792..275552
                     /locus_tag="ECs_0242"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion protein Rhs"
                     /protein_id="NP_308269.1"
                     /db_xref="GeneID:914218"
                     /translation="MPWLHRETARSFGGAGSTAGYEQVTAYTLTGQLQSRHLNLPQLD
                     CDYDWNDNGQLIRISGPQESREYRYSDTGRLTGVHTTAANLDIDIPYATDPAGNRLPD
                     PELHPDSTLTAWPDNRIAEDAHYVYRYDEYGRLTEKTDRIPEGVIRMHDERTHHYHYD
                     NQHRLVFYTRIQYGEPLVESRYLYDPLGRRTGKRVWRRERDLTGWMSLSRKPEVTWYG
                     WDGDRLTTVQTGTTRIQTVYRPGSFTPLIRIETENGEREKAQRRSLAEKLQQEGSEDG
                     HGVVFPAELVRMLDRLEEEIRADRVSSESRAWLAQCGLTVEQLEKQVEPEYTPARTLH
                     LYHCDHRGLPLALISEDGNTAWSAEYDEWGNQLNEENPHHLHQPYRLPGQQHDEESGL
                     YYNRHRYYDPLQGRYITPDPIGLRGGWNMYQYPLNPIQVIDPMGLDAIENMTSGGLIY
                     AVSGVPGLIVANSITNSAYQFGYDMDAIVGGAHNGAADAMRYCYLMCRMTKTFGSTIA
                     DVIGKNHEAAGDRQGQPAKERIMDLKNNTVGIACGDFSAKCSDACIEKYNIGQLFGLD
                     GIKADNPIKAKQGSSDASNY"
     misc_feature    <273828..275549
                     /locus_tag="ECs_0242"
                     /note="Uncharacterized conserved protein RhsA, contains 28
                     RHS repeats [General function prediction only]; Region:
                     RhsA; COG3209"
                     /db_xref="CDD:225750"
     gene            275536..275706
                     /locus_tag="ECs_0243"
                     /db_xref="GeneID:914228"
     CDS             275536..275706
                     /locus_tag="ECs_0243"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308270.1"
                     /db_xref="GeneID:914228"
                     /translation="MLQIIRGKLVIFLITLCLFVVYLGFDNNSNSDIVFYGHKTPKSV
                     EIYLSEKILFIK"
     gene            275754..276017
                     /locus_tag="ECs_0244"
                     /db_xref="GeneID:914250"
     CDS             275754..276017
                     /locus_tag="ECs_0244"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308271.1"
                     /db_xref="GeneID:914250"
                     /translation="MVNNYKTHCGVVDINLNFFNDILYSVRLKNISKLENMEFCATKQ
                     RVYFSDKNKKASYKIINYGDYYDVDYYDNNLKNEVFDWIGKWS"
     repeat_region   276083..277387
                     /note="ISEc26 Family: ISAs1"
     gene            276198..277370
                     /gene="yncI"
                     /locus_tag="ECs_0245"
                     /db_xref="GeneID:914277"
     CDS             276198..277370
                     /gene="yncI"
                     /locus_tag="ECs_0245"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308272.1"
                     /db_xref="GeneID:914277"
                     /translation="MSIQSLLDYISVIPDIRQQGKVKHKLSDILFLTVCAVIAGADEW
                     QEIEDFGHERLEWLKKYGDFDNGIPVDDTIARVVSNIDSLAFEKIFIEWMQECHEITD
                     GEIIAIDGKTIRGSFDKGKRKGAIHMVSAFSNENGVVLGQVKTEAKSNEITAIPELLN
                     LLDLKKNLITIDAMGCQKDIASKIKDKKADYLLAVKGNQGKLHHAFEEKFPVNVFSNY
                     KGDSFSTQEISHGRKETRLHIVSNVTPEFCDFEFEWKGLKKLCVALSFRQKKEDKSAE
                     GVSIRYYISSKDMDAKEFAHAIRAHWLIEHSLHWVLDVKMNEDASRIRRGNAAEIISG
                     IKKMALNLLRDCKDIKGGVKRKRKKVALNTCYIEEVLASCSELGFRTDKMKNLTQI"
     misc_feature    276282..277226
                     /gene="yncI"
                     /locus_tag="ECs_0245"
                     /note="ISAs1 family transposase; Region: transpos_ISAs1;
                     NF033564"
                     /db_xref="CDD:411194"
     gene            complement(277488..278258)
                     /gene="yafV"
                     /locus_tag="ECs_0246"
                     /db_xref="GeneID:914330"
     CDS             complement(277488..278258)
                     /gene="yafV"
                     /locus_tag="ECs_0246"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding C-N hydrolase family amidase"
                     /protein_id="NP_308273.1"
                     /db_xref="GeneID:914330"
                     /translation="MPGLKITLLQQPLVWMDGPANLRHFDRQLEGITGRDVIVLPEMF
                     TSGFAMEAAASSLAQDDVVNWMTAKAQQCNALIAGSVALQTESGSVNRFLLVEPGGTV
                     HFYDKRHLFRMADEHLHYKAGNARVIVEWRGWRILPLVCYDLRFPVWSRNLNDYDLAI
                     YVANWPAPRSLHWQALLTARAIENQAYVAGCNRVGSDGNGCHYRGDSRVINPQGEIIA
                     TADAHQATRIDAELSMVALREYREKFPAWRDADEFRLR"
     misc_feature    complement(277491..278258)
                     /gene="yafV"
                     /locus_tag="ECs_0246"
                     /note="C-N hydrolase family amidase; Provisional; Region:
                     PRK10438"
                     /db_xref="CDD:182461"
     misc_feature    complement(order(277764..277769,277824..277829,
                     277833..277838,277911..277913,277926..277928,
                     277938..277940,278115..278117,278133..278135))
                     /gene="yafV"
                     /locus_tag="ECs_0246"
                     /note="putative active site [active]"
                     /db_xref="CDD:143599"
     misc_feature    complement(order(277836..277838,277938..277940,
                     278133..278135))
                     /gene="yafV"
                     /locus_tag="ECs_0246"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:143599"
     misc_feature    complement(order(277500..277517,277521..277532,
                     277569..277571,277575..277580,277584..277586,
                     277596..277622,277626..277628,277710..277715,
                     277719..277727,277731..277736,277743..277748,
                     277806..277808,277812..277826,277833..277835,
                     277920..277922,277932..277937))
                     /gene="yafV"
                     /locus_tag="ECs_0246"
                     /note="multimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:143599"
     misc_feature    complement(order(277500..277517,277521..277532,
                     277614..277622,277710..277715,277719..277727,
                     277731..277736,277743..277748,277806..277808,
                     277812..277826,277833..277835,277920..277922,
                     277932..277937))
                     /gene="yafV"
                     /locus_tag="ECs_0246"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:143599"
     gene            278439..278885
                     /gene="ivy"
                     /locus_tag="ECs_0247"
                     /db_xref="GeneID:914333"
     CDS             278439..278885
                     /gene="ivy"
                     /locus_tag="ECs_0247"
                     /codon_start=1
                     /transl_table=11
                     /product="inhibitor of c-type lysozyme"
                     /protein_id="NP_308274.2"
                     /db_xref="GeneID:914333"
                     /translation="MFKAITTVAALVIATSAMAQDDLTISSLAKGETTKAAFNQMVQG
                     HKLPAWVMKGGTYTPAQTVTLGDETYQVMSACKPHDCGSQRIAVMWSEKSNQMTGLFS
                     TIDEKTSQEKLTWLNVNDALSIDGKTVLFAALTGSLENHPDGFNFK"
     misc_feature    278439..278882
                     /gene="ivy"
                     /locus_tag="ECs_0247"
                     /note="C-lysozyme inhibitor; Provisional; Region:
                     PRK09993"
                     /db_xref="CDD:182187"
     gene            complement(278928..281372)
                     /gene="fadE"
                     /locus_tag="ECs_0248"
                     /db_xref="GeneID:914334"
     CDS             complement(278928..281372)
                     /gene="fadE"
                     /locus_tag="ECs_0248"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl coenzyme A dehydrogenase"
                     /protein_id="NP_308275.2"
                     /db_xref="GeneID:914334"
                     /translation="MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWS
                     AWVLVPLAIILVPFNFAPMRKSMISAPVFRGFRKVMPPMSRTEKEAIDAGTTWWEGDL
                     FQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLK
                     EHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGT
                     DEQKDHYLPRLARGQEIPCFALTSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWN
                     KRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTPGVEIGRRHFPLNVP
                     FQNGPTLGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALA
                     TGAYAHIRRQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAI
                     VKYHCTHRGQQSIIDAMDITGGKGIMLGQSNFLARAYQGAPIAITVEGANILTRSMMI
                     FGQGAIRCHPYVLEEMEAAKNNDVNVFDKLLFKHIGHVGSNKVRSFWLGLTRGLTSST
                     PTGDATKRYYQHLNRLSANLALLSDVSMAVLGGSLKRRERISARLGDILSQLYLASAV
                     LKRYDDEGRNEADLPLVHWGVQDALYQAEQAMDDLLQNFPNRVVAGLLNVVIFPTGRH
                     YLAPSDKLDHKVAKILQVPNATRSRIGRGQYLTPSEHNPVGLLEEALVDVIAADPIHQ
                     RICKELGKNLPFTRLDELAHNALAKGLIDKDEAAILVKAEESRLRSINVDDFDPEELA
                     TKPVKLPEKVRKVEAA"
     misc_feature    complement(278931..281366)
                     /gene="fadE"
                     /locus_tag="ECs_0248"
                     /note="acyl-CoA dehydrogenase FadE; Region: FadE_coli;
                     NF038187"
                     /db_xref="CDD:439499"
     gene            281612..282190
                     /gene="gmhA"
                     /locus_tag="ECs_0249"
                     /db_xref="GeneID:914335"
     CDS             281612..282190
                     /gene="gmhA"
                     /locus_tag="ECs_0249"
                     /codon_start=1
                     /transl_table=11
                     /product="D-sedoheptulose 7-phosphate isomerase"
                     /protein_id="NP_308276.1"
                     /db_xref="GeneID:914335"
                     /translation="MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAG
                     GKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFS
                     RYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEI
                     RVPHFGYADRIQEIHIKVIHILIQLIEKEMVK"
     misc_feature    281612..282187
                     /gene="gmhA"
                     /locus_tag="ECs_0249"
                     /note="D-sedoheptulose 7-phosphate isomerase; Region:
                     gmhA; PRK00414"
                     /db_xref="CDD:179012"
     misc_feature    order(281648..281650,281660..281662,281702..281704,
                     281711..281713,281771..281773,281789..281794,
                     282125..282130,282140..282142,282149..282151,
                     282161..282163,282173..282175)
                     /gene="gmhA"
                     /locus_tag="ECs_0249"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:240139"
     misc_feature    order(281765..281773,281966..281974,281981..281983,
                     282110..282112,282125..282127)
                     /gene="gmhA"
                     /locus_tag="ECs_0249"
                     /note="active site"
                     /db_xref="CDD:240139"
     gene            282295..283062
                     /gene="yafJ"
                     /locus_tag="ECs_0250"
                     /db_xref="GeneID:914337"
     CDS             282295..283062
                     /gene="yafJ"
                     /locus_tag="ECs_0250"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 glutamine amidotransferase family
                     protein"
                     /protein_id="NP_308277.1"
                     /db_xref="GeneID:914337"
                     /translation="MCELLGMSANVPTDICFSFTGLVQRGGGTGPHKDGWGITFYEGK
                     GCRTFKDPQPSFNSPIAKLVQDYPIKSCSVVAHIRQANRGEVALENTHPFTRELWGRN
                     WTYAHNGQLTGYKSLETGNFRPVGKTDSEKAFCWLLYKLTQRYPRTPGNMAAVFKYIA
                     SLADELRQKGVFNMLLSDGRYVMAYCSTNLHWITRRAPFGVATLLDQDVEIDFSSQTT
                     PNDVVTVIATQPLTGNETWQKIMPGEWRLFCLGERVV"
     misc_feature    282295..283050
                     /gene="yafJ"
                     /locus_tag="ECs_0250"
                     /note="Glutamine amidotransferases class-II; Region:
                     GATase_4; pfam13230"
                     /db_xref="CDD:433047"
     misc_feature    order(282298..282300,282529..282531,282616..282624,
                     282679..282681)
                     /gene="yafJ"
                     /locus_tag="ECs_0250"
                     /note="putative active site [active]"
                     /db_xref="CDD:238889"
     misc_feature    order(282433..282435,282442..282447,282580..282582,
                     282652..282657,282718..282720)
                     /gene="yafJ"
                     /locus_tag="ECs_0250"
                     /note="putative dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:238889"
     gene            complement(283033..283773)
                     /gene="yafK"
                     /locus_tag="ECs_0251"
                     /db_xref="GeneID:914338"
     CDS             complement(283033..283773)
                     /gene="yafK"
                     /locus_tag="ECs_0251"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase-related protein"
                     /protein_id="NP_308278.1"
                     /db_xref="GeneID:914338"
                     /translation="MRKIALILAMLLIPCVSFAGLLGSSSSTTPVSKEYKQQLMGSPV
                     YIQIFKEERTLDLYVKMGEQYQLLDSYKICKYSGGLGPKQRQGDFKSPEGFYSVQRNQ
                     LKPDSRYYKAINIGFPNAYDRAHGYEGKYLMIHGDCVSIGCYAMTNQGIDEIFQFVTG
                     ALVFGQPSVQVSIYPFRMTDANMKRHKYSNFKDFWEQLKPGYDYFEQTRKPPTVSVVN
                     GRYVVSKPLSHEVVQPQLASNYTLPEAK"
     misc_feature    complement(283036..283773)
                     /gene="yafK"
                     /locus_tag="ECs_0251"
                     /note="Murein L,D-transpeptidase YafK [Cell
                     wall/membrane/envelope biogenesis]; Region: YafK; COG3034"
                     /db_xref="CDD:225577"
     gene            complement(283929..284189)
                     /gene="yafQ"
                     /locus_tag="ECs_0252"
                     /db_xref="GeneID:914339"
     CDS             complement(283929..284189)
                     /gene="yafQ"
                     /locus_tag="ECs_0252"
                     /codon_start=1
                     /transl_table=11
                     /product="predicted toxin of the YafQ-DinJ toxin-antitoxin
                     system"
                     /protein_id="NP_308279.1"
                     /db_xref="GeneID:914339"
                     /translation="MNSGQFSKDVKLAQKRHKDMNKLKYLMTLLINNTLPLPAVYKDH
                     PLQGSWKGYRDAHVEPDWILIYKLTDKLLRFERTGTHAALFG"
     misc_feature    complement(283935..284189)
                     /gene="yafQ"
                     /locus_tag="ECs_0252"
                     /note="mRNA-degrading endonuclease (mRNA interferase)
                     YafQ, toxin component of the YafQ-DinJ toxin-antitoxin
                     module [Translation, ribosomal structure and biogenesis];
                     Region: YafQ; COG3041"
                     /db_xref="CDD:225583"
     gene            complement(284208..284468)
                     /gene="dinJ"
                     /locus_tag="ECs_0253"
                     /db_xref="GeneID:914340"
     CDS             complement(284208..284468)
                     /gene="dinJ"
                     /locus_tag="ECs_0253"
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin of YafQ-DinJ toxin-antitoxin system"
                     /protein_id="NP_308280.1"
                     /db_xref="GeneID:914340"
                     /translation="MAANAFVRARIDEDLKNQAADVLAGMGLTISDLVRITLTKVARE
                     KALPFDLREPNQLTIQSIKNSEAGVDVHKAKDADDLFDKLGV"
     misc_feature    complement(284217..284459)
                     /gene="dinJ"
                     /locus_tag="ECs_0253"
                     /note="RelB antitoxin; Region: RelB; pfam04221"
                     /db_xref="CDD:427796"
     gene            284654..285427
                     /gene="yafL"
                     /locus_tag="ECs_0254"
                     /db_xref="GeneID:914343"
     CDS             284654..285427
                     /gene="yafL"
                     /locus_tag="ECs_0254"
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase"
                     /protein_id="NP_308281.2"
                     /db_xref="GeneID:914343"
                     /translation="MHDQPLLSMSLPSIPSFVLSGLLLICLPFSSFASATTSHISFSY
                     AARQRMQNRARLLKQYQTHLKKQVSYIVEGNAESRRALRQHNREQIKQHPEWFPAPLK
                     ASDRRWQALAENNHFLSSDHLHNITEVAIHRLEQQLGKPYVWGGTRPDKGFDCSGLVF
                     YAYNKILEAKLPRTANEMYHYHRATIVANNDLRRGDLLFFHIHSREIADHMGVYLGDG
                     QFIESPRTGETIRVSRLAEPFWQDHFLGARRILTEETIL"
     misc_feature    <284978..285397
                     /gene="yafL"
                     /locus_tag="ECs_0254"
                     /note="Cell wall-associated hydrolase, NlpC family [Cell
                     wall/membrane/envelope biogenesis]; Region: Spr; COG0791"
                     /db_xref="CDD:223862"
     gene            285603..285899
                     /gene="yafM"
                     /locus_tag="ECs_0255"
                     /pseudogene="unknown"
                     /db_xref="GeneID:62676014"
     misc_feature    285603..285899
                     /gene="yafM"
                     /locus_tag="ECs_0255"
                     /note="hypothetical protein"
                     /pseudogene="unknown"
     gene            complement(286245..287984)
                     /gene="flhA"
                     /locus_tag="ECs_0256"
                     /db_xref="GeneID:62676015"
     CDS             complement(286245..287984)
                     /gene="flhA"
                     /locus_tag="ECs_0256"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export pore protein"
                     /protein_id="NP_308284.2"
                     /db_xref="GeneID:62676015"
                     /translation="MLSRSDLLTLLTINFIVVTKGAERISEVSARFTLDAMPGKQMAI
                     DADLNAGLINQAQAQTRRKDVASEADFYGAMDGASKFVRGDAIAGMMILAINLIGGVC
                     IGIFKYNLSADAAFQQYVLMTIGDGLVAQIPSLLLSTAAAIIVTRVSDNGDIAHDVRH
                     QLLASPSVLYTATGIMFVLAVVPGMPHLPFLLFSALLGFTGWRMSKQPQAAEAEEKSL
                     ETLTRTITETSEQQVSWETIPLIEPISLSLGYKLVALVDKAQGNPLTQRIRGVRQVIS
                     DGNGVLLPEIRIRENFRLKPSQYAIFINGIKADEADIPADKLMALPSSETYGEIDGVL
                     GNDPAYGMPVTWIQPAQKAKALNMGYQVIDSASVIATHVNKIVRSYIPDLFNYDDITQ
                     LHNRLSSMAPRLAEDLSAALNYSQLLKVYRALLTEGVSLRDIVTIATVLVASSAVTKD
                     HILLAADVRLALRRSITHPFVRKQELTVYTLNNELENLLTNVVNQAQQGGKVMLDSVP
                     VDPNMLNQFQSTMPQVKEQMKAAGKDPVLLVPPQLRPLLARYARLFAPGLHVLSYNEV
                     PDELELKIMGALS"
     misc_feature    complement(286248..287963)
                     /gene="flhA"
                     /locus_tag="ECs_0256"
                     /note="Flagellar biosynthesis pathway, component FlhA
                     [Cell motility]; Region: FlhA; COG1298"
                     /db_xref="CDD:224217"
     gene            288079..288714
                     /gene="mbhA"
                     /locus_tag="ECs_0257"
                     /db_xref="GeneID:62676021"
     CDS             288079..288714
                     /gene="mbhA"
                     /locus_tag="ECs_0257"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar system protein MbhA"
                     /protein_id="NP_308283.2"
                     /db_xref="GeneID:62676021"
                     /translation="MAVPEETEKKARDVNEKTALLKKKSATELGELATSINTIARDAH
                     MEANLEMEIVPQGLRVLIKDDQNRNMFERGSAQIMPFFKTLLVELAPVFDSLDNKIII
                     TGHTDAMAYKNNIYNNWNLSGDRALSARRVLEEAGMPEDKVMQVSAMADQMLLDAKNP
                     QSAGNRRIEIMVLTKSASDTLYQYFGQHGDKVVQPLVQKLDKQQVLSQRTR"
     misc_feature    <288079..288690
                     /gene="mbhA"
                     /locus_tag="ECs_0257"
                     /note="hypothetical protein; Validated; Region: PRK06778"
                     /db_xref="CDD:235860"
     gene            288785..289840
                     /gene="dinB"
                     /locus_tag="ECs_0258"
                     /db_xref="GeneID:914349"
     CDS             288785..289840
                     /gene="dinB"
                     /locus_tag="ECs_0258"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="NP_308285.1"
                     /db_xref="GeneID:914349"
                     /translation="MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTA
                     NYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSL
                     DEAYLDVTDSVHCHGSATLIAQEIRQTIFSELQLTASAGVTPVKFLAKIASDMNKPNG
                     QFVITPAEVSAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVILLKRFGKF
                     GRILWERSQGIDERDVNSERLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAK
                     VKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATARKTWDERRGGRGVRLVGL
                     HVTLLDPQMERQLVLGL"
     misc_feature    288809..289837
                     /gene="dinB"
                     /locus_tag="ECs_0258"
                     /note="DNA polymerase IV; Validated; Region: PRK02406"
                     /db_xref="CDD:235035"
     gene            289892..290185
                     /gene="yafN"
                     /locus_tag="ECs_0259"
                     /db_xref="GeneID:914352"
     CDS             289892..290185
                     /gene="yafN"
                     /locus_tag="ECs_0259"
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin of the YafO-YafN toxin-antitoxin
                     system"
                     /protein_id="NP_308286.1"
                     /db_xref="GeneID:914352"
                     /translation="MHRILAEKSVNITELRKNPAKYFIDQPVAVLSNNRPAGYLLSAS
                     AFEALMDMLAEQEEKKPIKARFRPSAARLEEITRRAEKYLNDMTDDDFNDFKE"
     misc_feature    289892..290182
                     /gene="yafN"
                     /locus_tag="ECs_0259"
                     /note="type I toxin-antitoxin system antitoxin YafN;
                     Region: PRK09778"
                     /db_xref="CDD:170091"
     gene            290188..290586
                     /gene="yafO"
                     /locus_tag="ECs_0260"
                     /db_xref="GeneID:914353"
     CDS             290188..290586
                     /gene="yafO"
                     /locus_tag="ECs_0260"
                     /codon_start=1
                     /transl_table=11
                     /product="mRNA interferase toxin of the YafO-YafN
                     toxin-antitoxin system"
                     /protein_id="NP_308287.1"
                     /db_xref="GeneID:914353"
                     /translation="MRVFKTKLIRLQLTAEELDALTADFISYKRDGVLPDIFGRDALY
                     DDSFTWPLIKFERVAHIHLANVNNPFPPQLRQFSRTNDESHLVYCQGAFDEQAWLLIA
                     ILKPEPHKLARDNNQMHKIGKMAEAFRMRF"
     misc_feature    290188..290583
                     /gene="yafO"
                     /locus_tag="ECs_0260"
                     /note="type II toxin-antitoxin system YafO family toxin;
                     Region: PRK09885"
                     /db_xref="CDD:236631"
     gene            290671..291048
                     /gene="yafP"
                     /locus_tag="ECs_0261"
                     /db_xref="GeneID:914355"
     CDS             290671..291048
                     /gene="yafP"
                     /locus_tag="ECs_0261"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="NP_308288.2"
                     /db_xref="GeneID:914355"
                     /translation="MMTASQHYSPQQIAAWAQIDESRWKEKLAKSQVRVAVINAQPVG
                     FISRIEHYIDMLFVDPEYTRRGVASALLKPWIKSESELTVDASITAKPFFERYGFQTV
                     KQQRVECRGAWFTNFSMRYKPQH"
     misc_feature    290671..291045
                     /gene="yafP"
                     /locus_tag="ECs_0261"
                     /note="GNAT family N-acetyltransferase; Region: PRK09831"
                     /db_xref="CDD:182099"
     misc_feature    order(290836..290844,290872..290877)
                     /gene="yafP"
                     /locus_tag="ECs_0261"
                     /note="Coenzyme A binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:173926"
     gene            291355..291621
                     /gene="ykfJ"
                     /locus_tag="ECs_0262"
                     /db_xref="GeneID:914358"
     CDS             291355..291621
                     /gene="ykfJ"
                     /locus_tag="ECs_0262"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308289.1"
                     /db_xref="GeneID:914358"
                     /translation="MEWYMGKYIRPLSDAVFTIASDDLWIESLAIQQLHTTANLPNMQ
                     RVVGMPDLHPGRGYPIGAAFFSVGRFYPTRRRGNGAGNRNGPLL"
     misc_feature    291367..>291573
                     /gene="ykfJ"
                     /locus_tag="ECs_0262"
                     /note="RNA-splicing ligase RtcB, repairs tRNA damage
                     [Translation, ribosomal structure and biogenesis]; Region:
                     RtcB; cl22450"
                     /db_xref="CDD:419835"
     gene            291590..292090
                     /gene="prfH"
                     /locus_tag="ECs_0263"
                     /db_xref="GeneID:914361"
     CDS             291590..292090
                     /gene="prfH"
                     /locus_tag="ECs_0263"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor RF-1"
                     /protein_id="NP_308290.1"
                     /db_xref="GeneID:914361"
                     /translation="MLETETGRYSDTLRSALISLDGDNAWALSESWCGTIQWICLSPY
                     RPHHGRKNWFLGIGRFTADEQEQSDAIRYETLRPSGPGGQHVNKTDSAVRATHLATGI
                     SVKVQSERSQHANKRLARLLIAWKLEQQQQENSAVLKSQRRMFHHQIERGNPRRTFTG
                     MAFIEG"
     misc_feature    291590..292078
                     /gene="prfH"
                     /locus_tag="ECs_0263"
                     /note="Protein chain release factor B [Translation,
                     ribosomal structure and biogenesis]; Region: PrfB;
                     cl42823"
                     /db_xref="CDD:456168"
     gene            complement(292147..293604)
                     /gene="pepD"
                     /locus_tag="ECs_0264"
                     /db_xref="GeneID:914362"
     CDS             complement(292147..293604)
                     /gene="pepD"
                     /locus_tag="ECs_0264"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="NP_308291.1"
                     /db_xref="GeneID:914362"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKG
                     FHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDG
                     EWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQSNWL
                     QADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGG
                     EIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDAL
                     KSLVNTYQEILKNELAEKEKNLALLLDSVANDKAALIAKSRDTFIRLLNATPNGVIRN
                     SDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEA
                     KGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIG
                     PTITGPHSPDEQVHIESVGHYWTLLTELLKEIPAK"
     misc_feature    complement(292150..293604)
                     /gene="pepD"
                     /locus_tag="ECs_0264"
                     /note="aminoacyl-histidine dipeptidase; Provisional;
                     Region: PRK15026"
                     /db_xref="CDD:184986"
     misc_feature    complement(order(292459..292464,292471..292476,
                     292483..292485,292594..292599,292606..292608,
                     292627..292632,292636..292641,292735..292737,
                     292747..292749,292906..292908,292936..292938))
                     /gene="pepD"
                     /locus_tag="ECs_0264"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:349885"
     gene            293865..294323
                     /gene="gpt"
                     /locus_tag="ECs_0265"
                     /db_xref="GeneID:914363"
     CDS             293865..294323
                     /gene="gpt"
                     /locus_tag="ECs_0265"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="NP_308292.1"
                     /db_xref="GeneID:914363"
                     /translation="MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR"
     misc_feature    293865..294320
                     /gene="gpt"
                     /locus_tag="ECs_0265"
                     /note="xanthine-guanine phosphoribosyltransferase;
                     Validated; Region: PRK09177"
                     /db_xref="CDD:236395"
     misc_feature    order(293970..293972,293976..293978,294126..294134,
                     294138..294152,294207..294209)
                     /gene="gpt"
                     /locus_tag="ECs_0265"
                     /note="active site"
                     /db_xref="CDD:206754"
     gene            294415..295659
                     /gene="frsA"
                     /locus_tag="ECs_0266"
                     /db_xref="GeneID:914364"
     CDS             294415..295659
                     /gene="frsA"
                     /locus_tag="ECs_0266"
                     /codon_start=1
                     /transl_table=11
                     /product="fermentation-respiration switch protein"
                     /protein_id="NP_308293.1"
                     /db_xref="GeneID:914364"
                     /translation="MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTI
                     PHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     TQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
                     AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYF
                     APRGIAMLTIDMPSVGFSSKWKLTQDSCLLHQRVLKALPNVPWVDHTRVAAFGFRFGA
                     NVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEA
                     LRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFN
                     PVYRNFDKGLQEITDWIEKRLC"
     misc_feature    294415..295656
                     /gene="frsA"
                     /locus_tag="ECs_0266"
                     /note="esterase FrsA; Region: frsA; PRK05077"
                     /db_xref="CDD:235337"
     gene            295717..296118
                     /gene="crl"
                     /locus_tag="ECs_0267"
                     /db_xref="GeneID:914365"
     CDS             295717..296118
                     /gene="crl"
                     /locus_tag="ECs_0267"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Crl"
                     /protein_id="NP_308294.1"
                     /db_xref="GeneID:914365"
                     /translation="MTLPSGHPKSRLIKKFTVLGPYIREGKCEDNRFFFDCLAVCVNV
                     KPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWKSVPVKDTEVVERLEHTLRE
                     FHEKLRELLTTLNLKLEPADDFRDEPVKLTA"
     misc_feature    295717..296097
                     /gene="crl"
                     /locus_tag="ECs_0267"
                     /note="sigma factor-binding protein Crl; Region: PRK10984"
                     /db_xref="CDD:182882"
     gene            complement(296157..297212)
                     /gene="phoE"
                     /locus_tag="ECs_0268"
                     /db_xref="GeneID:914366"
     CDS             complement(296157..297212)
                     /gene="phoE"
                     /locus_tag="ECs_0268"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane phosphoporin protein E"
                     /protein_id="NP_308295.1"
                     /db_xref="GeneID:914366"
                     /translation="MKKSTLALVVMGIVASASVQAAEIYNKDGNKLDVYGKVKAMHYM
                     SDNDSKDGDQSYIRFGFKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGL
                     KYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFF
                     GVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQN
                     LQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPITGGFANKTQNFEAVAQYQF
                     DFGLRPSLGYVLSKGKDIEGIGDEDLVNYIDVGATYYFNKNMSAFVDYKINQLDSDNK
                     LNINNDDIVAVGMTYQF"
     misc_feature    complement(296160..297212)
                     /gene="phoE"
                     /locus_tag="ECs_0268"
                     /note="phosphoporin PhoE; Region: PRK10159"
                     /db_xref="CDD:182275"
     misc_feature    complement(order(296160..296162,296166..296168,
                     296172..296174,296259..296261,296268..296273,
                     296763..296768,296772..296774,296871..296879,
                     296907..296921,296925..296930,296961..296972,
                     296976..296978,296982..296990,296994..296996,
                     297012..297026,297087..297095,297099..297101,
                     297117..297119,297123..297125))
                     /gene="phoE"
                     /locus_tag="ECs_0268"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238208"
     misc_feature    complement(order(296772..296774,296832..296834,
                     296925..296927,297039..297041,297102..297104))
                     /gene="phoE"
                     /locus_tag="ECs_0268"
                     /note="eyelet of channel [active]"
                     /db_xref="CDD:238208"
     gene            297500..298603
                     /gene="proB"
                     /locus_tag="ECs_0269"
                     /db_xref="GeneID:914367"
     CDS             297500..298603
                     /gene="proB"
                     /locus_tag="ECs_0269"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamate kinase"
                     /protein_id="NP_308296.1"
                     /db_xref="GeneID:914367"
                     /translation="MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHR
                     IVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQML
                     LTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILA
                     GADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKL
                     QAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAG
                     EITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDA
                     LRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR"
     misc_feature    297512..298597
                     /gene="proB"
                     /locus_tag="ECs_0269"
                     /note="glutamate 5-kinase; Region: proB; TIGR01027"
                     /db_xref="CDD:162163"
     gene            298615..299868
                     /gene="proA"
                     /locus_tag="ECs_0270"
                     /db_xref="GeneID:914368"
     CDS             298615..299868
                     /gene="proA"
                     /locus_tag="ECs_0270"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylphosphate reductase"
                     /protein_id="NP_308297.1"
                     /db_xref="GeneID:914368"
                     /translation="MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILN
                     ANAQDVADARANGLSEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSG
                     LRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVVVIQ
                     DALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVI
                     TGGIGVCHIYVDESAEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIAYSFLPALSKQ
                     MAESGVTLHADASALAQLQTGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIR
                     EHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLH
                     ARGPMGLEALTTYKWIGIGDYTIRA"
     misc_feature    298615..299865
                     /gene="proA"
                     /locus_tag="ECs_0270"
                     /note="gamma-glutamyl phosphate reductase; Provisional;
                     Region: proA; PRK00197"
                     /db_xref="CDD:234685"
     misc_feature    299371..299373
                     /gene="proA"
                     /locus_tag="ECs_0270"
                     /note="putative catalytic cysteine [active]"
                     /db_xref="CDD:143398"
     gene            299983..300058
                     /gene="thrW"
                     /locus_tag="ECs_R0028"
                     /db_xref="GeneID:62676022"
     tRNA            299983..300058
                     /gene="thrW"
                     /locus_tag="ECs_R0028"
                     /product="tRNA-Thr"
                     /note="anticodon: cgt"
                     /db_xref="GeneID:62676022"
     misc_feature    300042..310627
                     /product="prophage Sp1, lambda-like phage"
     gene            complement(300073..301047)
                     /gene="intD"
                     /locus_tag="ECs_0271"
                     /pseudogene="unknown"
                     /db_xref="GeneID:62676023"
     misc_feature    complement(300073..301047)
                     /gene="intD"
                     /locus_tag="ECs_0271"
                     /note="integrase"
                     /pseudogene="unknown"
     gene            complement(300938..301183)
                     /locus_tag="ECs_0272"
                     /db_xref="GeneID:914371"
     CDS             complement(300938..301183)
                     /locus_tag="ECs_0272"
                     /codon_start=1
                     /transl_table=11
                     /product="phage early gene regulator"
                     /protein_id="NP_308299.1"
                     /db_xref="GeneID:914371"
                     /translation="MCDTKRSIGRKCESGLAANVPLRGVFVQDYDSHTQPKLTNRRIQ
                     MDAQTRRRERRAEKQAQWKADRILASTFRRNATKRHY"
     misc_feature    complement(<300992..301048)
                     /locus_tag="ECs_0272"
                     /note="36-mer N-terminal peptide of the N protein (N36);
                     Region: N36; pfam11438"
                     /db_xref="CDD:288317"
     gene            complement(301423..301812)
                     /locus_tag="ECs_0273"
                     /db_xref="GeneID:914372"
     CDS             complement(301423..301812)
                     /locus_tag="ECs_0273"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308300.1"
                     /db_xref="GeneID:914372"
                     /translation="MKKAAILIDAGFFMQRVHATHRKHFAEHELTAQCIMKVIWSMVL
                     SHLNGKRQSQERREPLELYRIYFYDCPPLDIQTRLPLPEPGNKTPGRKNFKLEKSYIL
                     RTELHEELRKTRKTPIVFILKLIGATH"
     misc_feature    complement(<301567..301806)
                     /locus_tag="ECs_0273"
                     /note="PIN (PilT N terminus) domain: Superfamily; Region:
                     PIN_SF; cl28905"
                     /db_xref="CDD:452894"
     gene            complement(301940..302653)
                     /locus_tag="ECs_0274"
                     /db_xref="GeneID:914373"
     CDS             complement(301940..302653)
                     /locus_tag="ECs_0274"
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein CI"
                     /protein_id="NP_308301.1"
                     /db_xref="GeneID:914373"
                     /translation="MSAKKKPLTQEQLEDARRLKAIYEKKKNELGLSQESVADKMGMG
                     QSGVGALFNGINALNAYNAALLAKILNVSVEEFSPSIAREIYEMYEAVSMQPSLRSEY
                     EYPVFSHVQAGMFSPELRTFTKGDAEKWVSTTKKASGSAFWLEVEGNSMTAPTGSKPS
                     FPDGMLILVDPEQAVEPGDFCIARLGGDEFTFKKLIRDSGQVFLQPLNPQYPMIPCNE
                     SCSVVGKVIASQWPEETFG"
     misc_feature    complement(301952..302590)
                     /locus_tag="ECs_0274"
                     /note="SOS-response transcriptional repressor LexA
                     (RecA-mediated autopeptidase) [Transcription, Signal
                     transduction mechanisms]; Region: LexA; COG1974"
                     /db_xref="CDD:224885"
     gene            302754..302954
                     /locus_tag="ECs_0275"
                     /db_xref="GeneID:914374"
     CDS             302754..302954
                     /locus_tag="ECs_0275"
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor Cro"
                     /protein_id="NP_308302.1"
                     /db_xref="GeneID:914374"
                     /translation="MEQRITLKDYAMRFGQTKTAKDLGVYQSAINKAIHAGRKIFLTI
                     NADGSVYAEEVKPFPSNKKTTA"
     misc_feature    302760..302933
                     /locus_tag="ECs_0275"
                     /note="Region: Cro; pfam09048"
                     /db_xref="CDD:430385"
     gene            303073..303366
                     /locus_tag="ECs_0276"
                     /db_xref="GeneID:914375"
     CDS             303073..303366
                     /locus_tag="ECs_0276"
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein CII"
                     /protein_id="NP_308303.1"
                     /db_xref="GeneID:914375"
                     /translation="MVRANKRNEALRIESALLNKIAMLGTEKTAEAVGVDKSQISRWK
                     RDWIPKFSMLLAVLEWGVVDDDMARLARQVAAILTNKKRPAATERSEQIQMEF"
     misc_feature    303082..303318
                     /locus_tag="ECs_0276"
                     /note="Bacteriophage CII protein; Region: Phage_CII;
                     pfam05269"
                     /db_xref="CDD:398780"
     gene            303399..304321
                     /locus_tag="ECs_0277"
                     /pseudogene="unknown"
                     /db_xref="GeneID:62676024"
     misc_feature    303399..304321
                     /locus_tag="ECs_0277"
                     /note="phage replication protein O"
                     /pseudogene="unknown"
     gene            304318..304629
                     /locus_tag="ECs_0279"
                     /pseudogene="unknown"
                     /db_xref="GeneID:62676025"
     misc_feature    304318..304629
                     /locus_tag="ECs_0279"
                     /note="phage repliction protein P"
                     /pseudogene="unknown"
     gene            304629..305423
                     /locus_tag="ECs_0280"
                     /db_xref="GeneID:914379"
     CDS             304629..305423
                     /locus_tag="ECs_0280"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail fiber protein"
                     /protein_id="NP_308307.1"
                     /db_xref="GeneID:914379"
                     /translation="MAKNDFKAFATDRNANVMSQEEWEALPALISGFTAGKASSAQVN
                     KVIRQASFIAAALAQFVSDKTQRDVLDNGDLPGFVELLGSGFAVEYLSRKNPFGDIKS
                     DGTVKTALQNLGLGEGAPAIGVPFFWPSAAMPNTVIDSWSCMVFLKFNGAKFSATDYP
                     VLAKVFPSLVLPEARGDFIRIWDDGRGADGGRELLSWQAATNFSQFAGNIGEGAGHAI
                     NFHDGIAGNQPGFSRFNFTSNSVGDGVNFVAVRPRNIAFNFLVRAK"
     gene            305423..306016
                     /gene="tfaE"
                     /locus_tag="ECs_0281"
                     /db_xref="GeneID:914380"
     CDS             305423..306016
                     /gene="tfaE"
                     /locus_tag="ECs_0281"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail fiber assembly protein"
                     /protein_id="NP_308308.1"
                     /db_xref="GeneID:914380"
                     /translation="MKPVFDENGLATVPGDMRCFYYDAETSEYTGWSDEYINTGVSMP
                     ACSTGIDPGENIPGRVAVFTGKGWSHEEDHRNETVYSIENGAAVTVDYIGAIKDGYVT
                     ISPLTPYDKWDGEKWVTDTEAQHSAAVDAAEAQRQSLIDAAMASISLIQLKLQAGRKL
                     TQAETTRLNAVLDYIDAVTATDTSTAPDVIWPELPEA"
     misc_feature    <305705..306010
                     /gene="tfaE"
                     /locus_tag="ECs_0281"
                     /note="Caudovirales tail fibre assembly protein, lambda
                     gpK; Region: Caudo_TAP; pfam02413"
                     /db_xref="CDD:426761"
     gene            complement(305988..306431)
                     /gene="yfdK"
                     /locus_tag="ECs_0282"
                     /db_xref="GeneID:914381"
     CDS             complement(305988..306431)
                     /gene="yfdK"
                     /locus_tag="ECs_0282"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail fiber assembly protein"
                     /protein_id="NP_308309.1"
                     /db_xref="GeneID:914381"
                     /translation="MDEYVYSARHNAFFPVDMIDKYKSEGWDLSDAKEVNQNIISEFM
                     AEPPQGKIRIAGDDGLPAWADIPPPTHEELIEITESERQLLINQANEYMNSKQWPGKA
                     AIGRLKGDELTQYNLWLDYLDALELVDTSGAPDIEWPTPPAVQAR"
     misc_feature    complement(306003..306401)
                     /gene="yfdK"
                     /locus_tag="ECs_0282"
                     /note="Caudovirales tail fibre assembly protein, lambda
                     gpK; Region: Caudo_TAP; pfam02413"
                     /db_xref="CDD:396812"
     gene            complement(306452..306862)
                     /gene="yfdL"
                     /locus_tag="ECs_0283"
                     /db_xref="GeneID:914382"
     CDS             complement(306452..306862)
                     /gene="yfdL"
                     /locus_tag="ECs_0283"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="NP_308310.1"
                     /db_xref="GeneID:914382"
                     /translation="MPFARYFCIFINVGLGEAAKRDVGTGENQIPDMASFASGNGWMK
                     LPNGKILQYGRGAVTPTLSTQTMRITFSIPFPKKADCAMLTHSGDGGAPLGAGRGFVM
                     TAEGPTLTGFNSAYRTSSTSDTVSMNYSWWAVGE"
     gene            306892..307446
                     /gene="pinE"
                     /locus_tag="ECs_0284"
                     /db_xref="GeneID:914383"
     CDS             306892..307446
                     /gene="pinE"
                     /locus_tag="ECs_0284"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-invertase"
                     /protein_id="NP_308311.1"
                     /db_xref="GeneID:914383"
                     /translation="MLIGYVRVSTNDQNTDLQRNALNCAGCELIFEDKISGTKSERPG
                     LKKLLRTLSAGDTLVVWKLDRLGRSMRHLVILVEELRERGVNFRSLTDAIDTSTPMGR
                     FFFHVMGALAEMERELIVERTKAGLEAARAQGRIGGRRPKLTPEQWAQAGRLIAAGIP
                     RQKVAIIYDVGVSTLYKKFPAGDK"
     misc_feature    306895..307269
                     /gene="pinE"
                     /locus_tag="ECs_0284"
                     /note="Serine Recombinase (SR) family, Resolvase and
                     Invertase subfamily, catalytic domain; members contain a
                     C-terminal DNA binding domain. Serine recombinases
                     catalyze site-specific recombination of DNA molecules by a
                     concerted, four-strand cleavage and...; Region: SR_ResInv;
                     cd03768"
                     /db_xref="CDD:239737"
     misc_feature    order(306910..306912,306916..306918,307081..307086,
                     307093..307095)
                     /gene="pinE"
                     /locus_tag="ECs_0284"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239737"
     misc_feature    306916..306918
                     /gene="pinE"
                     /locus_tag="ECs_0284"
                     /note="catalytic nucleophile [active]"
                     /db_xref="CDD:239737"
     misc_feature    order(307078..307080,307210..307215,307219..307224,
                     307234..307236)
                     /gene="pinE"
                     /locus_tag="ECs_0284"
                     /note="Presynaptic Site I dimer interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:239737"
     misc_feature    order(307096..307098,307111..307116,307198..307200,
                     307207..307212,307219..307224,307231..307233,
                     307240..307242)
                     /gene="pinE"
                     /locus_tag="ECs_0284"
                     /note="Synaptic Antiparallel dimer interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:239737"
     misc_feature    order(307165..307173,307198..307203,307210..307215,
                     307222..307224,307234..307236,307243..307245,
                     307255..307257)
                     /gene="pinE"
                     /locus_tag="ECs_0284"
                     /note="Synaptic Flat tetramer interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:239737"
     misc_feature    order(307165..307167,307213..307215,307222..307224,
                     307234..307236,307243..307245,307255..307257)
                     /gene="pinE"
                     /locus_tag="ECs_0284"
                     /note="Synaptic Site I dimer interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:239737"
     misc_feature    order(307237..307239,307255..307260)
                     /gene="pinE"
                     /locus_tag="ECs_0284"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:239737"
     misc_feature    307303..307437
                     /gene="pinE"
                     /locus_tag="ECs_0284"
                     /note="Helix-turn-helix domain of resolvase; Region:
                     HTH_7; pfam02796"
                     /db_xref="CDD:397088"
     misc_feature    order(307306..307314,307408..307413,307417..307422)
                     /gene="pinE"
                     /locus_tag="ECs_0284"
                     /note="DNA-binding interface [nucleotide binding]; DNA
                     binding site"
                     /db_xref="CDD:259851"
     gene            complement(307504..308277)
                     /locus_tag="ECs_0285"
                     /db_xref="GeneID:914384"
     CDS             complement(307504..308277)
                     /locus_tag="ECs_0285"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308312.1"
                     /db_xref="GeneID:914384"
                     /translation="MDITEFPSGVIEHLGWYVYRLIDPRDGSTFYVGKGKGNRVFAHM
                     RGEVAAADDDDLLSNKLKQIREIRLAGLEVIHVIHRHGMTDEKTAYEVEAALIDAYPG
                     LTNIMNGAGSNEFGAAHVKELIATYQPETITFHHKALMISVNRSAKDSELYDAVRFSW
                     RINVSRASKAEVILATVRGIVRGVFIADKWLKSTREHFPTMKYWDEDPDFEATQSSRY
                     GFEGREAPPEIANLYLGKKIPDELRKKGAMSPVRYSPNF"
     misc_feature    complement(307507..308277)
                     /locus_tag="ECs_0285"
                     /note="Uncharacterized protein [Function unknown]; Region:
                     COG3680"
                     /db_xref="CDD:226205"
     gene            309101..309844
                     /locus_tag="ECs_0287"
                     /db_xref="GeneID:914386"
     CDS             309101..309844
                     /locus_tag="ECs_0287"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription regulator"
                     /protein_id="NP_308314.1"
                     /db_xref="GeneID:914386"
                     /translation="MATTCSVILILESFDVYFGKESVFLERGSSVLVDSSSRDFFLTY
                     PERVIVADFGAEFISRYLKANNLRDISDCREYPSYLKINFADFSLIKGLISWANHCAE
                     YIEIFDESIAFTCLSAFSSEKQFGVFLFGCLKSTGAKVKTIIHTDLSAPWRLKDISSR
                     LYLSESLLKRKLKEEGVSFSKIILDERMQMAEYLLSTRCYPISKVAKVCGYASVSYFT
                     YVFRRYFGVSPSQYSQRSSESKILTHQGI"
     misc_feature    309101..309841
                     /locus_tag="ECs_0287"
                     /note="transcriptional regulator YdeO; Provisional;
                     Region: PRK09940"
                     /db_xref="CDD:182157"
     repeat_region   complement(309849..310318)
                     /note="ISEc48 Family: IS3 partial"
     gene            complement(309886..310239)
                     /locus_tag="ECs_0288"
                     /db_xref="GeneID:914387"
     CDS             complement(309886..310239)
                     /locus_tag="ECs_0288"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_308315.1"
                     /db_xref="GeneID:914387"
                     /translation="MLGAIEKRFGDKVPEQSIQWLTDNGSAYRAHETRQFARELNLEP
                     CTTAISSPQSNGIAERFVKTMKEDYIAFMPKPNVRTALHNLAVAIEHYNENHPHSALG
                     YRSPREYRRQRVTLT"
     misc_feature    complement(309901..>310239)
                     /locus_tag="ECs_0288"
                     /note="IS2 transposase TnpB; Reviewed; Region: PRK09409"
                     /db_xref="CDD:181829"
     misc_feature    310628..323514
                     /product="prophage Sp2, P4-like phage"
     gene            310807..311988
                     /gene="intS"
                     /locus_tag="ECs_0289"
                     /db_xref="GeneID:914388"
     CDS             310807..311988
                     /gene="intS"
                     /locus_tag="ECs_0289"
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="NP_308316.1"
                     /db_xref="GeneID:914388"
                     /translation="MPLNDMQIRRAKPEAKAYTFGDGLGLSLLIEPNGSKSWRFRYRY
                     AGKPKMISLGVYPTITLADARSRRDEARKLVAEGKNPSEVRKEQKLAMQTESENAFEK
                     IAREWHQLKSAKWSAGYASDIMEAFKNDIFPYVGTRPVGEIKPLELLNVLRKIEKRGA
                     LEKMRKVRQRCSEVFRYAIATGRAEYNPAADLSSALEVHQSNHFPFLKADEIPDFLRA
                     LEGYSGSKLVQIATKLLMITGVRTIELRAALWQEFDLDNAIWEIPAERMKMRRPHLVP
                     LSSQAVDLLNELKIMTGNYRYVFPGRNDPNRPMSEASINQAIKRIGYGGKVTGHGFRH
                     TLSTILHEQGFESAWIEIQLAHVDKNSIRGTYNHAQYFSGRKSMMDWYSNLIFERLKR
                     S"
     misc_feature    310810..311964
                     /gene="intS"
                     /locus_tag="ECs_0289"
                     /note="integrase; Provisional; Region: PRK09692"
                     /db_xref="CDD:170049"
     gene            311992..312408
                     /locus_tag="ECs_0290"
                     /db_xref="GeneID:914389"
     CDS             311992..312408
                     /locus_tag="ECs_0290"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308317.1"
                     /db_xref="GeneID:914389"
                     /translation="MSQPLSEILTWDDEQWEVFVHDWLIVCKSDDYPWSERLGGAGDK
                     GRDVVGYKSDPNVEGYSWDNYQCKLYKKSLGFSDVVVEFGKLIYFTLNGDYPIPQKYF
                     FVAPYDLSTTFSNLLKNKNELKKAVLDSWDSAISKK"
     gene            312381..312998
                     /locus_tag="ECs_0291"
                     /db_xref="GeneID:914390"
     CDS             312381..312998
                     /locus_tag="ECs_0291"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308318.1"
                     /db_xref="GeneID:914390"
                     /translation="MGFSNFKKITKKIDIPLDDEIKKYIEDFDFSIFYSLPLSLILND
                     IANTHLYFKYFNELYVVRIPPNEIPTYNSKKESVYVNALLQAYSEHGNKTYSSFLELD
                     DPYRRHFNNSRNDFYFASSLEVFVREVFKDDVFKALKCYISSSIEPVFYEDHNYAFIR
                     CNAVLKQAVLTPIAHSVLSKICEANDKKGICHHLVNDGEVIWTVR"
     gene            312998..313456
                     /locus_tag="ECs_0292"
                     /db_xref="GeneID:914391"
     CDS             312998..313456
                     /locus_tag="ECs_0292"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308319.1"
                     /db_xref="GeneID:914391"
                     /translation="MVRIYNSSLEVACRMAKVLVAIYPSSLSLERLICFDFILVNLKD
                     FLPEEISLHPPIPRRDAQLALKREIVLESLALLQGYELASKIYTHRGFVYKASEKTYA
                     FTNSLHNEYVAQMEHNINLVVKLYSDIPDEQLQSIIKNKIGKYDMEFNYE"
     gene            313449..315268
                     /locus_tag="ECs_0293"
                     /pseudogene="unknown"
                     /db_xref="GeneID:62676026"
     misc_feature    313449..315268
                     /locus_tag="ECs_0293"
                     /note="AAA family ATPase"
                     /pseudogene="unknown"
     gene            complement(315678..315950)
                     /locus_tag="ECs_0296"
                     /db_xref="GeneID:914395"
     CDS             complement(315678..315950)
                     /locus_tag="ECs_0296"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription activator"
                     /protein_id="NP_308323.1"
                     /db_xref="GeneID:914395"
                     /translation="MALKCPECGTTAHARTSAYEAPSVKRSWYQCQNLECSYTFTALE
                     SVDTIIMKPRRNEQESEKAQMPEKQQQTLNRYGSASKLSSRQQIPV"
     misc_feature    complement(315801..315941)
                     /locus_tag="ECs_0296"
                     /note="Ogr/Delta-like zinc finger; Region: Ogr_Delta;
                     pfam04606"
                     /db_xref="CDD:428030"
     gene            complement(315956..316507)
                     /locus_tag="ECs_0297"
                     /db_xref="GeneID:914396"
     CDS             complement(315956..316507)
                     /locus_tag="ECs_0297"
                     /codon_start=1
                     /transl_table=11
                     /product="phage polarity suppression protein"
                     /protein_id="NP_308324.1"
                     /db_xref="GeneID:914396"
                     /translation="MMARVTPDQALISFRNARILWAGHSESRKAVEQQIESLLTAMEK
                     PADYARQLELQREHLDVLKWQINCAARECIYSQHQLMEACTEDALSNFMQANGAALTS
                     ALAPFLKGRGGVDVASRILRNALVRQLAITPPEIAGDYRMILDESGVMPDPMMVRDCQ
                     SSYTPAQQLRFQQRLDYINGMQE"
     misc_feature    complement(315986..316483)
                     /locus_tag="ECs_0297"
                     /note="Phage polarity suppression protein (Psu); Region:
                     Psu; pfam07455"
                     /db_xref="CDD:429469"
     gene            complement(316504..317256)
                     /locus_tag="ECs_0298"
                     /db_xref="GeneID:914397"
     CDS             complement(316504..317256)
                     /locus_tag="ECs_0298"
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid size determining protein"
                     /protein_id="NP_308325.1"
                     /db_xref="GeneID:914397"
                     /translation="MTIPEQNNNPIVEISIPVSTQQALEKVNATKSAWLEARRQQKAA
                     ADNIATIRQRRAEMEATTNALNEEWRTLFRESQGVVSKEMKKLRTEIALGRETLEDFD
                     ELLAAQESENALLPQEAAELAGKYIHAHDTLVGIRAKQIWEDFMQSHGKALIQTLSLL
                     KSTMGREASAVVGVVHSVNDPDTLLKDFIHKHITRPALTNDAMPEQDPVFKLAGVAPD
                     YAARLDFSNKLSPAAMHKMKVRQERAEKEKAV"
     gene            318190..318450
                     /locus_tag="ECs_0299"
                     /db_xref="GeneID:914398"
     CDS             318190..318450
                     /locus_tag="ECs_0299"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_308326.1"
                     /db_xref="GeneID:914398"
                     /translation="MRNISVSAPAPAAPLFPVSNHHERFLRLPEVMHLCGLSRSTVYD
                     LISRDAFPKQIPLGGKNVAWAQSEVSAWMADRISARGRGCDA"
     misc_feature    318235..318435
                     /locus_tag="ECs_0299"
                     /note="Predicted DNA-binding transcriptional regulator
                     AlpA [Transcription, Mobilome: prophages, transposons];
                     Region: AlpA; COG3311"
                     /db_xref="CDD:225848"
     gene            318447..319004
                     /locus_tag="ECs_0300"
                     /db_xref="GeneID:914399"
     CDS             318447..319004
                     /locus_tag="ECs_0300"
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
                     /protein_id="NP_308327.1"
                     /db_xref="GeneID:914399"
                     /translation="MMIPAYIKYLYSGLLTVVISRYSFSAVAKSAAGIGVPYNLLATI
                     DAPCVFFYVVAQAQPFSGLWCLCLHHGSIEIMVVRAGQPSGWPVSNKAGYANPVRAAT
                     SEIGVSGGSNNRYLLEAAIMATILTPSHPQYVFVFAAIRRADTHPRICMLRTVSCDER
                     SARRLLVRDYVLSLSARLPAGEVTL"
     misc_feature    318522..318842
                     /locus_tag="ECs_0300"
                     /note="Ash protein family; Region: Phage_ASH; pfam10554"
                     /db_xref="CDD:431354"
     misc_feature    318843..318986
                     /locus_tag="ECs_0300"
                     /note="host cell division inhibitor Icd domain; Region:
                     phage_ICD_like; NF033153"
                     /db_xref="CDD:411097"
     gene            319001..319222
                     /locus_tag="ECs_0301"
                     /db_xref="GeneID:914400"
     CDS             319001..319222
                     /locus_tag="ECs_0301"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308328.1"
                     /db_xref="GeneID:914400"
                     /translation="MNQFEISYDDVVRLKHLRNVGEYVTGMAALQDCYEKPAGAQCEQ
                     LVSLIYLMTEQLDGVVQRCHDDLMNAEVA"
     gene            319222..319545
                     /locus_tag="ECs_0302"
                     /db_xref="GeneID:914401"
     CDS             319222..319545
                     /locus_tag="ECs_0302"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308329.1"
                     /db_xref="GeneID:914401"
                     /translation="MICCESLLALRAALYRRAVACAWLALSNHQERYSGLTLAELEDA
                     IARELEGFYLRQHGQQRGLEIACALLSDLMESGPLKACPVLSLLGMTVMDELCSRHLN
                     KPALH"
     misc_feature    319249..319542
                     /locus_tag="ECs_0302"
                     /note="Family of unknown function (DUF5375); Region:
                     DUF5375; pfam17345"
                     /db_xref="CDD:435875"
     gene            319559..321892
                     /locus_tag="ECs_0303"
                     /db_xref="GeneID:914402"
     CDS             319559..321892
                     /locus_tag="ECs_0303"
                     /codon_start=1
                     /transl_table=11
                     /product="phage DNA primase"
                     /protein_id="NP_308330.1"
                     /db_xref="GeneID:914402"
                     /translation="MSGMKVSQAEKAARGHWSRILPALGVNVLKNRHQPCPVCAGKDR
                     FRFDDQEGRGTWFCNQCGAGDGLALVSKVLDVGISEAADRINGIIGNLLPVSQGMLES
                     GSPEKEDGRKAAAVLAARLFDKSRQTTGNAYLTSKGFPALPCRELTAMHKVGGVAFRA
                     GDLVVPLYADGELVNLQLINANGGKCFLKGGQVKNAFYLVEGTAKAAKRLWIAEGYAT
                     ALTINYLTGDAVMVAFSSVNFLSLASIACSEYPTHQIIIAADRDLNGAGQTRGAAVTG
                     ACNCTMALPPVFGDWNDAFTQNGEEATRHAIHEVIKPAVASPFDTMSEAEFTALSVSE
                     KAQRVVDHYKNSLAVDPNGQLLSRYEAGAWKVIYYADFARDVAALFQRLDAPFSSAKI
                     ASLVETLKLIVPQQQNPARQLIGFRNGVLDTRTGLFSPHDKKHWLRTLCEVDYTQPVD
                     GESLETHAPAFWRWLDRAAGFNPEKRDIILAALFMVLANRYDWQLFLEVTGPGGSGKS
                     ILAEIATMLAGEDNATSATIEMLESPRERAALIGFSLIRLPDQEKWSGDGAGLKAITG
                     GDAVSVDPKYQNAYSTHIPAVILAVNNNPMRFTDRSGGVSRRRVILHFPDQIAPEERD
                     TQLKEKIASELAVIVRQLMQRFSDPMSARTLLQSQQNSDEALTIKRDADSAFDFCGYL
                     EVLPDTTGMFMGNANIVPRQPRTYLYHAYLVYMEANGYKNTLSLTMFGKGLPLMLKEY
                     GLQYEKRRTNQGMQTNLALREESNADWLPKCDEFAAK"
     misc_feature    319562..320662
                     /locus_tag="ECs_0303"
                     /note="Uncharacterized domain associated with
                     phage/plasmid primase [Mobilome: prophages, transposons];
                     Region: COG4643"
                     /db_xref="CDD:226990"
     misc_feature    320654..321889
                     /locus_tag="ECs_0303"
                     /note="Phage- or plasmid-associated DNA primase [Mobilome:
                     prophages, transposons]; Region: COG3378"
                     /db_xref="CDD:225913"
     gene            complement(322025..322981)
                     /locus_tag="ECs_0304"
                     /db_xref="GeneID:914403"
     CDS             complement(322025..322981)
                     /locus_tag="ECs_0304"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308331.1"
                     /db_xref="GeneID:914403"
                     /translation="MTSYSNFSNQIKETINNKFDHEIHDWDIIKNSITTLINKNIHGA
                     GRNIVDFIDLGNWDFISNFSFDDSTRRLELEWHPNDKFHIYIESVVFVEFNDTIYAFL
                     KGYYHNQLSLNRIYNTKCSSCSFENSGSYMVDVYRTVKRVNETIQTPNINCYTTCILT
                     RPANGHVTSTGFSRNLMDAINISLAEHKIASLHNEVMSIEEYDRDSLQEKGNTARRYL
                     EYILMLVNIRIMHLNNVQYQEQMLGSLVSVIEALDYEPLMKNDVEITKDILNACSHHG
                     GVRIEKKDVIFSLEVIENLIKAIKKTDINKLQLDGMFKSIQK"
     gene            complement(323657..324556)
                     /gene="yagP"
                     /locus_tag="ECs_0305"
                     /db_xref="GeneID:914404"
     CDS             complement(323657..324556)
                     /gene="yagP"
                     /locus_tag="ECs_0305"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="NP_308332.2"
                     /db_xref="GeneID:914404"
                     /translation="MKIDLNLLPIFIAVAEESNFSKAAARLGVTRSAVSQGIRRLEDA
                     FGTMLVMRTTRSVNLTEAGERLHKSLSLPLSGIEAAFEEMVSDHVPRGLLRIAVTSIA
                     EEFLSGPLIASFAAANPAVTLDIVVTDEEFDIVAAGYDAGVRLGEVIEKDMIAVPLTG
                     RQREMVVASPSYLAANSTPVHPRELVNHKCIGWRQSPEVAPYRWPFEENGRAFDLAIE
                     PQITTNDLRLMLRLALAGGGITIATQETFRPYIESGKLVSLLDDFLPQFPGFYLYFPQ
                     RRNIAPKLRALIDHVKEWRQQLA"
     misc_feature    complement(324365..324544)
                     /gene="yagP"
                     /locus_tag="ECs_0305"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:425479"
     misc_feature    complement(323684..324289)
                     /gene="yagP"
                     /locus_tag="ECs_0305"
                     /note="The C-terminal substrate binding domain of an
                     uncharacterized LysR-type transcriptional regulator
                     CrgA-like, contains the type 2 periplasmic binding fold;
                     Region: PBP2_CrgA_like_5; cd08474"
                     /db_xref="CDD:176163"
     misc_feature    complement(order(323747..323749,323828..323830,
                     323879..323881,324071..324073,324080..324082,
                     324122..324124,324239..324241,324251..324253))
                     /gene="yagP"
                     /locus_tag="ECs_0305"
                     /note="putative effector binding pocket [active]"
                     /db_xref="CDD:176163"
     misc_feature    complement(order(323852..323854,323861..323866,
                     323885..323899,323990..323992,324176..324196,
                     324200..324202,324212..324214,324221..324226,
                     324230..324235,324245..324250))
                     /gene="yagP"
                     /locus_tag="ECs_0305"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:176163"
     gene            324655..325377
                     /locus_tag="ECs_0306"
                     /db_xref="GeneID:914405"
     CDS             324655..325377
                     /locus_tag="ECs_0306"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="NP_308333.1"
                     /db_xref="GeneID:914405"
                     /translation="MDKVILITGASSGIGEGIARELGMTGAKVLLGARRVERIEAIAT
                     EICRAGGIAKARELDVTDRQSMADFVQAALDSWGRVDVLINNAGVMPLSPLAAGKQDE
                     WALTIDVNIKGVLWGIGAVLPVMEAQGSGQIINLGSIGALSVVPTGAVYCASKFAVRA
                     ISDGLRQESSKIRVTCVNPGVVESELASTITHVETMKAMDAYRSVALQPADIARAVRH
                     IIESPESVDTTEITIRPTASAN"
     misc_feature    324658..325374
                     /locus_tag="ECs_0306"
                     /note="NADP-dependent 3-hydroxy acid dehydrogenase YdfG
                     [Energy production and conversion]; Region: YdfG; COG4221"
                     /db_xref="CDD:226674"
     gene            325544..325822
                     /locus_tag="ECs_0307"
                     /db_xref="GeneID:914406"
     CDS             325544..325822
                     /locus_tag="ECs_0307"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308334.1"
                     /db_xref="GeneID:914406"
                     /translation="MSLYIKLILSIVREISVNTICSLIVVVALSLLSFSSVAKTITAV
                     GSTINSTEKEISLQAEKQGKSYKILGAFFKNRVYMIAKLTPVSKNDAS"
     gene            complement(326525..327427)
                     /locus_tag="ECs_0309"
                     /db_xref="GeneID:914408"
     CDS             complement(326525..327427)
                     /locus_tag="ECs_0309"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_308336.1"
                     /db_xref="GeneID:914408"
                     /translation="MKGNVSMAKRENYNELYLFMQVVREGSFTAAAKRLGLAQSGVSR
                     SVRELEERLGVQLLVRTTRKLSLTQAGEQLYQKTASGFEMLDLGLATLAHYRETPSGT
                     VRINASQHAIDKCLLPKLAVFKQRYPDIQLELINESRFVDIIEERFDAGVRLGPEVSQ
                     GMVAVRITPDMEMAIVGTPEHFRRYGFPQTPADLKAHPCIAYQFADGSVYQWELNQDD
                     KKITHQPEGQWAFSDSYMEAEAARLGLGLAYVPVELVADDLEHGKLIRVLQRYSLRME
                     GLFLYYPHRNVSPALRMVIDTLKI"
     misc_feature    complement(327212..327388)
                     /locus_tag="ECs_0309"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:425479"
     misc_feature    complement(326534..327133)
                     /locus_tag="ECs_0309"
                     /note="The C-terminal substrate binding domain of an
                     uncharacterized LysR-type transcriptional regulator
                     CrgA-like, contains the type 2 periplasmic binding fold;
                     Region: PBP2_CrgA_like_5; cd08474"
                     /db_xref="CDD:176163"
     misc_feature    complement(order(326594..326596,326675..326677,
                     326726..326728,326915..326917,326924..326926,
                     326966..326968,327083..327085,327095..327097))
                     /locus_tag="ECs_0309"
                     /note="putative effector binding pocket [active]"
                     /db_xref="CDD:176163"
     misc_feature    complement(order(326699..326701,326708..326713,
                     326732..326746,326834..326836,327020..327040,
                     327044..327046,327056..327058,327065..327070,
                     327074..327079,327089..327094))
                     /locus_tag="ECs_0309"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:176163"
     gene            327673..328731
                     /locus_tag="ECs_0310"
                     /db_xref="GeneID:914409"
     CDS             327673..328731
                     /locus_tag="ECs_0310"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308337.2"
                     /db_xref="GeneID:914409"
                     /translation="MSYADSTNPNAPVSMTDKWDKTFAESQKVDHRKVSFPNRYGITL
                     VGDLYLPKDRGDRKLAAIAVSGPFGAVKEQSSGLYAQTLAERGFVTLAFDPSYTGESG
                     GYPRNVASPDINTEDFSAAVDFLGLQKEVDRNRIGLLGICGWGGMALNDAAMDTRVKA
                     VATSVMYDMSRAMGHGVGDGEDRYSTADRRAVLQYLNEQRWKDAQSGTFAHGGHDINV
                     DSNGKVSAGERILPETLPANPHPVLKEFFDYYRMPRGFHERSVNSTGAWTATMPLSFM
                     NMPLLSYASEITIPTLIVTGEKAHSRYFAEDAYKAVGSKDKELVVVPGANHVDLYDNV
                     AGKIPFAKFEQFFQTKLK"
     misc_feature    327715..328728
                     /locus_tag="ECs_0310"
                     /note="Fermentation-respiration switch protein FrsA, has
                     esterase activity, DUF1100 family [Signal transduction
                     mechanisms]; Region: FrsA; COG1073"
                     /db_xref="CDD:223999"
     gene            328873..330000
                     /locus_tag="ECs_0311"
                     /db_xref="GeneID:914410"
     CDS             328873..330000
                     /locus_tag="ECs_0311"
                     /codon_start=1
                     /transl_table=11
                     /product="transport protein"
                     /protein_id="NP_308338.2"
                     /db_xref="GeneID:914410"
                     /translation="MTLCVFVLIASEFMPVSLLTPIARDLGVTEGLAGRGIAISGALA
                     VLTSLTLSTLAGKMNRKFLLLGMTVLMAVSGLIIALATSYLMYMVGRAMIGVAIGGFW
                     SMSAATAIRLVPQHQVTRALAIFNAGNALATVVAAPLGSYLGATVGWRGAFLCLVPMA
                     VVAFIWQCISLPSMDANKSHTSCGAVFRLFSRRMVVVGMIACGLFFMGQFALFTYVRP
                     FLESVTRVNSLGLSLILLIIGVAGFIGTLVVSIFLNRKCYPTLMAIPGLMAVIAIGLM
                     LTGHHVWMVSLLLGLWGMLATAAPTGWWTWIARTLPDNAEAGGGLMVAVIQLSIALGS
                     TAGGIVFDRLGWQSTFAMSSVLLLCAGVLTFVTARQKAGAL"
     misc_feature    328873..329988
                     /locus_tag="ECs_0311"
                     /note="Predicted arabinose efflux permease, MFS family
                     [Carbohydrate transport and metabolism]; Region: AraJ;
                     COG2814"
                     /db_xref="CDD:225371"
     gene            complement(330179..331135)
                     /gene="paoD"
                     /locus_tag="ECs_0313"
                     /db_xref="GeneID:914412"
     CDS             complement(330179..331135)
                     /gene="paoD"
                     /locus_tag="ECs_0313"
                     /codon_start=1
                     /transl_table=11
                     /product="moco insertion factor for PaoABC aldehyde
                     oxidoreductase"
                     /protein_id="NP_308340.1"
                     /db_xref="GeneID:914412"
                     /translation="MSYPLFDKDEHWHKPEQAFLTDDHRTILRFAVEALMSGKGAGLV
                     TLVEIRGGAARPLGAQMVVREDGRYCGFVSGGCVEAAAAFEALEMMGSGCDREIRYGE
                     GSPWFDIVLPCGGGITLTLHKLRSAQPLLAVLNRLEQRKPAGLRYDPQAQSLVCLPTQ
                     TRTGWNLNGFEVGFRPCVRLMIYGRSLEAQATASLAAATGYDSHIFDLFPASASAQID
                     TDTAVILLCHDLNRELPVLQAAREAKPFYLGALGSYRTHTLRLQKLHELGWSREETAQ
                     IRAPVGIFPKARNAHTLALSVLAEVASVRLHQEEDSCLPPSS"
     misc_feature    complement(330182..331063)
                     /gene="paoD"
                     /locus_tag="ECs_0313"
                     /note="Xanthine and CO dehydrogenase maturation factor,
                     XdhC/CoxF family [Posttranslational modification, protein
                     turnover, chaperones]; Region: XdhC; COG1975"
                     /db_xref="CDD:224886"
     gene            complement(331145..333343)
                     /gene="paoC"
                     /locus_tag="ECs_0314"
                     /db_xref="GeneID:914413"
     CDS             complement(331145..333343)
                     /gene="paoC"
                     /locus_tag="ECs_0314"
                     /codon_start=1
                     /transl_table=11
                     /product="moco-containing subunit of PaoABC aldehyde
                     oxidoreductase"
                     /protein_id="NP_308341.1"
                     /db_xref="GeneID:914413"
                     /translation="MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWHEE
                     SPNAAYGYIVGSAIAKGRLTALDTDAAQKAPGVLPVITASNAGALSKGDKNTARLLGG
                     PTIEHYHQAIALVVAETFEQARAAASLVQAHYRRNKGAYSLADEKQAVSQPPEDTPDK
                     NVGDFDGAFSSAAVKIDATYTTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRT
                     DLAKTLKVPVENVRIISPYIGGGFGGKLFLRSDALLAALAARAVKRPVKVMLPRPSIP
                     NNTTHRPATLQHLRIGADQSGKITAISHESWSGNLPGGTPETAVQQSELLYAGANRHT
                     GLRLATLDLPEGNAMRAPGEAPGLMALEIAIDELAEKAGIDPVEFRILNDTQIDPADP
                     TRRFSRRQLIECLRTGADKFGWKQRNATPGQVRDGEWLVGHGVAAGFRNNLLEKSGAR
                     VHLEPNGTVTVETDMTDIGTGSYTILAQTAAEMLGVPLEQVAVHLGDSSFPVSAGSGG
                     QWGANTSTSGVYAACVKLREMIASAVGFDPEQSQFADGKITNGTRSAILHEATAGGRL
                     TAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATGEVRVRRMLAVCAAGRILNPKTARS
                     QVIGAMTMGMGAALMEELAVDDRLGYFVNHDMAGYEVPVHADIPKQEVIFLDDTDPIS
                     SPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPITLDKLLDKLPDVV"
     misc_feature    complement(331154..333307)
                     /gene="paoC"
                     /locus_tag="ECs_0314"
                     /note="CO or xanthine dehydrogenase, Mo-binding subunit
                     [Energy production and conversion]; Region: CoxL; COG1529"
                     /db_xref="CDD:224446"
     gene            complement(333340..334296)
                     /gene="paoB"
                     /locus_tag="ECs_0315"
                     /db_xref="GeneID:914414"
     CDS             complement(333340..334296)
                     /gene="paoB"
                     /locus_tag="ECs_0315"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing subunit of PaoABC aldehyde
                     oxidoreductase"
                     /protein_id="NP_308342.1"
                     /db_xref="GeneID:914414"
                     /translation="MKAFTYERVNTPAEAALSAQRVPGAKFIAGGTNLLDLMKLEIET
                     PTHLIDVNGLGLDKIEVTDAGGLRIGALVRNTDLVAHERVRRDYAVLSRALLAGASGQ
                     LRNQATTAGNLLQRTRCPYFYDTNQPCNKRLPGSGCAALEGFSRQHAVVGVSEACIAT
                     HPSDMAVAMRLLDAVVETITPEGKTRSITLADFYHPPGKTPHIETALLPGELIVAVTL
                     PPPLGGKHIYRKVRDRASYTFALVSVAAIIQPDGSGRVALGGVAHKPWRIEAADAQLS
                     QGAQAVYDALFASAHPTAENTFKLLLAKRTLASVLAEARAQA"
     misc_feature    complement(333343..334296)
                     /gene="paoB"
                     /locus_tag="ECs_0315"
                     /note="CO or xanthine dehydrogenase, FAD-binding subunit
                     [Energy production and conversion]; Region: CoxM; COG1319"
                     /db_xref="CDD:224238"
     gene            complement(334293..334982)
                     /gene="yagT"
                     /locus_tag="ECs_0316"
                     /db_xref="GeneID:914415"
     CDS             complement(334293..334982)
                     /gene="yagT"
                     /locus_tag="ECs_0316"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase"
                     /protein_id="NP_308343.1"
                     /db_xref="GeneID:914415"
                     /translation="MSNQGEYPEDNRVGKHEPHDLSLTRRDLIKVSAATAAAAVVYPH
                     STLAASVPAATPAPEIMPLTLKVNGKTEQLEVDTRTTLLDALRENLHLIGTKKGCDHG
                     QCGACTVLVNGRRLNACLTLAVMHQGAEITTIEGLGSPDNLHPMQAAFIKHDGFQCGY
                     CTSGQICSSVAVLKEIQDGIPSHVTVDLVSPPERTADEIRERMSGNICRCGAYANILA
                     AIEDAAGEIKS"
     misc_feature    complement(334299..334949)
                     /gene="yagT"
                     /locus_tag="ECs_0316"
                     /note="aldehyde oxidoreductase 2Fe-2S subunit;
                     Provisional; Region: PRK11433"
                     /db_xref="CDD:236910"
     gene            335400..336014
                     /gene="yagU"
                     /locus_tag="ECs_0317"
                     /db_xref="GeneID:914416"
     CDS             335400..336014
                     /gene="yagU"
                     /locus_tag="ECs_0317"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308344.1"
                     /db_xref="GeneID:914416"
                     /translation="MNIFEQTPPNRRRYGLAAFIGLIAGVVSAFVKWGAEVPLPPRSP
                     VDMFNAACGPESLIRAAGQIDCSRNFLNPPYIFLRDWLGLTDPNAAVYTFAGHVFNWV
                     GVTHIIFSIVFAVGYCVVAEVFPKIKLWQGLLAGALAQLFVHMISFPLMGLTPPLFDL
                     PWYENVSEIFGHLVWFWSIEIIRRDLRNRITHEPDPEIPLGSNR"
     misc_feature    335406..335999
                     /gene="yagU"
                     /locus_tag="ECs_0317"
                     /note="Uncharacterized membrane protein YagU, involved in
                     acid resistance, DUF1440 family [Function unknown];
                     Region: YagU; COG3477"
                     /db_xref="CDD:226008"
     gene            complement(336904..337614)
                     /gene="ecpE"
                     /locus_tag="ECs_0319"
                     /db_xref="GeneID:914418"
     CDS             complement(336904..337614)
                     /gene="ecpE"
                     /locus_tag="ECs_0319"
                     /codon_start=1
                     /transl_table=11
                     /product="ECP production pilus chaperone"
                     /protein_id="NP_308346.2"
                     /db_xref="GeneID:914418"
                     /translation="MFRRRGVTLTKALLTAVCMLAAPLTQAISVGNLTFSLPSETDFV
                     SKRVVNNNKSARIYRIAISAIDSPGSSELRTRPVDGELLFAPRQLALQAGESEYFKFY
                     YHGPQDNRERYYRVSFREVPTRNLTKRSPTGGEVSTEPVVVMDTILVVRPRQVQFKWS
                     FDQVTGTVSNTGNTWFKLLIKPGCDSTEEEGDAWYLRPEDVVHQPELRQPGNHYLVYN
                     DKFIKISDSCPAKPPSAD"
     gene            complement(337583..339226)
                     /gene="ecpD"
                     /locus_tag="ECs_0320"
                     /db_xref="GeneID:914419"
     CDS             complement(337583..339226)
                     /gene="ecpD"
                     /locus_tag="ECs_0320"
                     /codon_start=1
                     /transl_table=11
                     /product="polymerized tip adhesin of ECP fibers"
                     /protein_id="NP_308347.1"
                     /db_xref="GeneID:914419"
                     /translation="MRVNLLIAMIIFALIWPVTALRAAVSKTTWADAPAREFVFVENN
                     SDDNFFVTPGGALDPRLTGANRWTGLKYNGSGTIYQQSLGYIDNGYNTGLYTNWKFDM
                     WLENSPVSSPLTGLRCINWYAGCNMTTSLILPQTTDTSGFYGATVTSGGAKWMHGMLS
                     DAFYQYLQQMPVGSSFTMTINACQTSVNYDASSGARCKDQASGNWYVRNVTHTKAANL
                     RLINTHSLAEVFINSDGVPTLGEGNADCRTQTIGSRSGLSCKMVNYTLQTNGLSNTSI
                     HIFPAIANSSLASAVGAYDMQFSLNGSSWKPVSNTAYYYTFNEMKSADSIYVFFSSNF
                     FKQMVNQGISDINTKDLFNFRFQNTTSPESGWYEFSTSNTLIIKPRDFSISIISDEYT
                     QTPSREGYVGSGESALDFGYIVTTSGKTAADEVLIKVTGPAQVIGGRSYCVFSSDDGK
                     AKVPFPATLSFITRNGATKTYDAGCDDSWRDMTDALWLTTPWTDISGEVGQMDKTTVK
                     FSIPMDNAISLRTVDDNGWFGEVSASGEIHVQATWRNIN"
     gene            complement(339216..341741)
                     /gene="ecpC"
                     /locus_tag="ECs_0321"
                     /db_xref="GeneID:914420"
     CDS             complement(339216..341741)
                     /gene="ecpC"
                     /locus_tag="ECs_0321"
                     /codon_start=1
                     /transl_table=11
                     /product="ECP production outer membrane protein"
                     /protein_id="NP_308348.1"
                     /db_xref="GeneID:914420"
                     /translation="MPLRRFSPGLKAQFAFGMVFLFVQPDASAADISAQQIGGVIIPQ
                     AFSQALQDGMSVPLYIHLAGSQGRQDDQRIGSAFIWLDDGQLRIRKIQLEESEDNASV
                     SEQTRQQLMALANAPFNEALTIPLTDNAQLDLSLRQLLLQLVVKREALGTVLRSRSED
                     IGQSSVNTLSSNLSYNFGIYNNQLRNGGSNTSSYLSLNNVTALREHHVVLDGSLYGIG
                     SGQQDSELYKAMYERDFAGHRFAGGTLDTWNLQSLGPMTAISAGKIYGLSWGNQASST
                     IFDSSQSATPVIAFLPAAGEVHLTRDGRLLSVQNFTMGNHEVDTRGLPYGIYDVEVEV
                     IVNGRVISKRTQRVNKLFSRGRGVGAPLAWQVWGGSFHMDRWSENGKKTRPAKESWLA
                     GASTSGSLSTLSWAATGYGYDNQAVGETRLTLPLGGAINVNLQNMLASDSSWSSIGSI
                     SATLPGGFSSLWVNQEKTRIGNQLRRSDADNRAIGGTLNLNSLWSKLGTFSISYNDDR
                     RYNSHYYTADYYQNVYSGTFGSLGLRAGIQRYNNGDSNANTGKYIALDLSLPLGNWFS
                     AGMTHQNGYTMANLSARKQFDEGTIRTVGANLSRAISGDTGDDKTLSGGAYAQFDARY
                     ASGTLNVNSAADGYVNTNLTANGSVGWQGKNIAASGRTDGNAGVIFNTGLEDDGQISA
                     KINGRIFPLNGKRNYLPLSPYGRYEVELQNSKNSLDSYDIVSGRKSHLTLYPGNVAVI
                     EPEVKQMVTVSGRIRAEDGTLLANARINNHIGRTRTDENGEFVMDVDKKYPTIDFRYS
                     GNKTCEVALELNQARGAVWVGDVVCSGLSSWAAVTQTGEENES"
     misc_feature    complement(339270..>341054)
                     /gene="ecpC"
                     /locus_tag="ECs_0321"
                     /note="fimbrial outer membrane usher protein TcfC;
                     Provisional; Region: PRK15310"
                     /db_xref="CDD:185210"
     misc_feature    complement(340692..340895)
                     /gene="ecpC"
                     /locus_tag="ECs_0321"
                     /note="E-set like domain; Region: TcfC; pfam16967"
                     /db_xref="CDD:435681"
     misc_feature    complement(339270..339548)
                     /gene="ecpC"
                     /locus_tag="ECs_0321"
                     /note="CS1-pili formation C-terminal; Region: CooC_C;
                     pfam15976"
                     /db_xref="CDD:435048"
     gene            complement(341767..342435)
                     /gene="ecpB"
                     /locus_tag="ECs_0322"
                     /db_xref="GeneID:914421"
     CDS             complement(341767..342435)
                     /gene="ecpB"
                     /locus_tag="ECs_0322"
                     /codon_start=1
                     /transl_table=11
                     /product="ECP production pilus chaperone"
                     /protein_id="NP_308349.1"
                     /db_xref="GeneID:914421"
                     /translation="MKKHLLLLALLLSGISPAQALDVGDISSFMNSDSSTLSKTIKNS
                     TDSGRLINIRLERLSSPLDDGQVISMDKPDELLLTPASLLLPAQASEVIRFFYKGPAD
                     EKERYYRIVWFDQALSDAQRDNANRSAVATASARIGTILVVAPRQANYHFQYANGTLT
                     NTGNATLRILAYGPCLKAANGKECKENYYLMPGKSRRFTRVDTADNKGRVALWQGDKF
                     IPVK"
     misc_feature    complement(<341911..>342249)
                     /gene="ecpB"
                     /locus_tag="ECs_0322"
                     /note="Pili and flagellar-assembly chaperone, PapD
                     N-terminal domain; Region: PapD_N; cl21716"
                     /db_xref="CDD:451367"
     misc_feature    complement(341773..341988)
                     /gene="ecpB"
                     /locus_tag="ECs_0322"
                     /note="EcpB C-terminal domain; Region: EcpB_C; pfam18649"
                     /db_xref="CDD:436646"
     gene            complement(342493..343080)
                     /gene="ecpA"
                     /locus_tag="ECs_0323"
                     /db_xref="GeneID:914422"
     CDS             complement(342493..343080)
                     /gene="ecpA"
                     /locus_tag="ECs_0323"
                     /codon_start=1
                     /transl_table=11
                     /product="ECP pilin"
                     /protein_id="NP_308350.1"
                     /db_xref="GeneID:914422"
                     /translation="MKKKVLAIALVTVFTGMGVAQAADVTAQAVATWSATAKKDTTSK
                     LVVTPLGSLAFQYAEGIKGFNSQKGLFDVAIEGDSTATAFKLTSRLITNTLTQLDTSG
                     STLNVGVDYNGAAVEKTGDTVMIDTANGVLGGNLSPLANGYNASNRTTAQDGFTFSII
                     SGTTNGTTAVTDYSTLPEGIWSGDVSVQFDATWTS"
     misc_feature    complement(342502..343005)
                     /gene="ecpA"
                     /locus_tag="ECs_0323"
                     /note="Fimbrillin MatB; Region: MatB; pfam16449"
                     /db_xref="CDD:435342"
     gene            complement(343155..343697)
                     /gene="ecpR"
                     /locus_tag="ECs_0324"
                     /db_xref="GeneID:914423"
     CDS             complement(343155..343697)
                     /gene="ecpR"
                     /locus_tag="ECs_0324"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator for the ecp operon"
                     /protein_id="NP_308351.2"
                     /db_xref="GeneID:914423"
                     /translation="MECQNRSDKYIWSPHDAYFYKGLSELIVDIDRLIYLSLEKIRKD
                     FVFINLNTDSLTEFINRDNEWLSAVKGKQVVLIAARKSEALANYWYYNSNIRGVVYAG
                     LSRDIRKELAYVINGRFLRKDIKKDKITDREMEIIRMTAQGMLPKSIARIENCSVKTV
                     YTHRRNAEAKLYSKLYKLVQ"
     misc_feature    complement(343185..>343490)
                     /gene="ecpR"
                     /locus_tag="ECs_0324"
                     /note="transcriptional regulator UhpA; Region: PRK10360"
                     /db_xref="CDD:182408"
     misc_feature    complement(<343185..343310)
                     /gene="ecpR"
                     /locus_tag="ECs_0324"
                     /note="helix_turn_helix, Lux Regulon; Region: HTH_LUXR;
                     smart00421"
                     /db_xref="CDD:197715"
     misc_feature    complement(order(343203..343217,343221..343226,
                     343230..343235,343257..343265,343302..343310))
                     /gene="ecpR"
                     /locus_tag="ECs_0324"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     gene            344522..344713
                     /gene="ykgL"
                     /locus_tag="ECs_0326"
                     /db_xref="GeneID:914425"
     CDS             344522..344713
                     /gene="ykgL"
                     /locus_tag="ECs_0326"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308353.1"
                     /db_xref="GeneID:914425"
                     /translation="MQAASQREETEWRVQSKRGLMPAYRGEAGQQVNINIMEYSERNV
                     RQLTLNEQEDTSPGKLMLV"
     gene            complement(344783..344923)
                     /gene="ykgO"
                     /locus_tag="ECs_5701"
                     /db_xref="GeneID:62676027"
     CDS             complement(344783..344923)
                     /gene="ykgO"
                     /locus_tag="ECs_5701"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="YP_009502590.1"
                     /db_xref="GeneID:62676027"
                     /translation="MKVLNSLRTAKERHPDCQIVKRKGRLYVICKSNPRFKAVQGRKK
                     KR"
     misc_feature    complement(344801..344923)
                     /gene="ykgO"
                     /locus_tag="ECs_5701"
                     /note="50S ribosomal protein L36; Validated; Region: rpmJ;
                     PRK00831"
                     /db_xref="CDD:179138"
     gene            complement(344923..345189)
                     /gene="ykgM"
                     /locus_tag="ECs_0327"
                     /db_xref="GeneID:914426"
     CDS             complement(344923..345189)
                     /gene="ykgM"
                     /locus_tag="ECs_0327"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31 type B"
                     /protein_id="NP_308354.2"
                     /db_xref="GeneID:914426"
                     /translation="MMKPNIHPEYRTVVFHDTSVDEYFKIGSTIKTDREIELDGVTYP
                     YVTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRFVSTKKGA"
     misc_feature    complement(344929..345186)
                     /gene="ykgM"
                     /locus_tag="ECs_0327"
                     /note="type B 50S ribosomal protein L31; Region: rpmE2;
                     PRK01678"
                     /db_xref="CDD:234969"
     repeat_region   345358..347799
                     /note="ISEc8 Family: IS66"
     gene            345450..345830
                     /locus_tag="ECs_0328"
                     /db_xref="GeneID:914427"
     CDS             345450..345830
                     /locus_tag="ECs_0328"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_308355.2"
                     /db_xref="GeneID:914427"
                     /translation="MQKNVTPGRRKGCPNYPPEFKQQLVAASCEPGISISKLALENGI
                     NANLLFKWRQQWREGKLLLPSSESPQLLPVTLDAAAEQPESLAEDPETLSISCEVTFR
                     HGTLRFNGNVSEKLLTLLIQELKR"
     misc_feature    <345474..345782
                     /locus_tag="ECs_0328"
                     /note="IS66-like element accessory protein TnpA; Region:
                     IS66_access_TnpA; NF038385"
                     /db_xref="CDD:439678"
     gene            345827..346174
                     /locus_tag="ECs_0329"
                     /db_xref="GeneID:914428"
     CDS             345827..346174
                     /locus_tag="ECs_0329"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_308356.1"
                     /db_xref="GeneID:914428"
                     /translation="MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVF
                     IFRGRSGSQVKLLWSTGDGLCLLTKRLERGRFAWPSARDGKVFLTQAQLAMLLEGIDW
                     RQPKRLLTSLTML"
     misc_feature    345863..346147
                     /locus_tag="ECs_0329"
                     /note="IS66 Orf2 like protein; Region: TnpB_IS66;
                     pfam05717"
                     /db_xref="CDD:428604"
     gene            346224..347762
                     /locus_tag="ECs_0330"
                     /db_xref="GeneID:914429"
     CDS             346224..347762
                     /locus_tag="ECs_0330"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_308357.1"
                     /db_xref="GeneID:914429"
                     /translation="MNDISSDDIFLLKQRLAEQEALIHALQEKLSNREREIDHLQAQL
                     DKLRRMNFGSRSEKVSRRIAQMEADLNRLQKESDTLTGRVYDPAVQRPLRQTRTRKPF
                     PESLPRDEKRLLPAAPCCPNCGGSLSYLGEDTAEQLELMRSAFRVIRTVREKHACTQC
                     DAIVQAPAPSRPIERGIAGPGLLARVLTSKYAEHTPLYRQSEIYGRQGVELRRSLLSG
                     WVDACCRLLSPLEEALHGYVMTDGKLHADDTPVQVLLPGNKKTKTGRLWAYVRDDRNA
                     GSALAPAVWFAYSPDRKGIHPQTHLACFSGVLQADAYAGFNELYRNGGITEAACWAHA
                     RRKIHDVHVRIPSALTEEALEQIGQLYAIEADIRGMPAEQRLAERQRKTKPLLKSLES
                     WLREKMKTLSRHSELAKAFAYALNQWPALTYYANDGWVEIDNNIAENALRAVSLGRKN
                     FLFFGSDHGGERGALLYSLIGTCKLNDVDPESYLRHVLGVIADWPVNRVSELLPWRIA
                     LPAE"
     misc_feature    346257..346367
                     /locus_tag="ECs_0330"
                     /note="Dimerization/Docking domain of Cyclic GMP-dependent
                     Protein Kinase I; Region: DD_cGKI; cl17044"
                     /db_xref="CDD:450144"
     misc_feature    order(346257..346259,346266..346271,346278..346283,
                     346290..346292,346299..346304,346311..346313,
                     346320..346325,346332..346334,346341..346346,
                     346353..346358,346362..346367)
                     /locus_tag="ECs_0330"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:213373"
     misc_feature    order(346293..346298,346302..346304,346308..346310)
                     /locus_tag="ECs_0330"
                     /note="putative GKAP docking site [polypeptide binding];
                     other site"
                     /db_xref="CDD:213373"
     misc_feature    346338..346553
                     /locus_tag="ECs_0330"
                     /note="Transposase C of IS166 homeodomain; Region:
                     LZ_Tnp_IS66; pfam13007"
                     /db_xref="CDD:432935"
     misc_feature    346494..347687
                     /locus_tag="ECs_0330"
                     /note="IS66 family transposase; Region: transpos_IS66;
                     NF033517"
                     /db_xref="CDD:411154"
     gene            complement(348574..349716)
                     /locus_tag="ECs_0331"
                     /db_xref="GeneID:914430"
     CDS             complement(348574..349716)
                     /locus_tag="ECs_0331"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="NP_308358.1"
                     /db_xref="GeneID:914430"
                     /translation="MTNKHPSLFSPFMLTEKIKLRNRIVMAPMTTWSANPDGTISEQE
                     LEFYKRRSQNVGLVITGCTYVTPSGIGFTHEFAAYDDRFINSLEKLAAAAKSGGAPAI
                     LQIFHAGNKAIPELVPNNDVISASASSVKSGDFMKRVVQSREMTENEIQETIRAFGDV
                     TKRAIKAGFDGIELHGAHGFLLQNFFSPLFNQRNDRWGGDLEGRMRFPLAVLQEVKNV
                     VYEYATKPFAIGYRISPEESATGGLRIEDTYKLLDRLISSGISYIHTSLVSINDSYPV
                     ESPNGPRTIELILNHIAGRVPVIAAGKIRTPSQAQEAISTGLPLVAIGKGLVINPEWV
                     TLAESGRGHEIQTTLNPQLVPELTIPDKLWDQIQASKGTGWFPLMD"
     misc_feature    complement(348625..349695)
                     /locus_tag="ECs_0331"
                     /note="Old yellow enzyme (OYE)-related FMN binding domain,
                     group 4. Each monomer of OYE contains FMN as a
                     non-covalently bound cofactor, uses NADPH as a reducing
                     agent with oxygens, quinones, and alpha,beta-unsaturated
                     aldehydes and ketones, and can act as...; Region:
                     OYE_like_4_FMN; cd04735"
                     /db_xref="CDD:240086"
     misc_feature    complement(order(348742..348747,349009..349011,
                     349177..349179,349405..349407,349531..349533,
                     349627..349629,349633..349635))
                     /locus_tag="ECs_0331"
                     /note="putative active site [active]"
                     /db_xref="CDD:240086"
     misc_feature    complement(order(348742..348747,349009..349011,
                     349405..349407,349531..349533,349627..349629,
                     349633..349635))
                     /locus_tag="ECs_0331"
                     /note="putative FMN binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:240086"
     misc_feature    complement(order(349177..349179,349183..349185))
                     /locus_tag="ECs_0331"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:240086"
     misc_feature    complement(349177..349179)
                     /locus_tag="ECs_0331"
                     /note="putative catalytic residue [active]"
                     /db_xref="CDD:240086"
     gene            complement(349951..350871)
                     /gene="ycjY"
                     /locus_tag="ECs_0332"
                     /db_xref="GeneID:914431"
     CDS             complement(349951..350871)
                     /gene="ycjY"
                     /locus_tag="ECs_0332"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="NP_308359.1"
                     /db_xref="GeneID:914431"
                     /translation="MKTVSIKHTYWDIAADIYFPDDFNSEKKYPAIISAHPIGSCKEQ
                     TSGSVYGAALAKAGFIVIAFDASFQGSSGGEPRYLEDPTMRVKDFSIVVDYLTSLPYV
                     DAGRIGVLGICGGGGYAINAAMTERRIKAIGTVTGANYGRLMREGFTAFNPIGALEAM
                     AQQRTDEANGAKLRVDDLLPSSPDAALEAGLTEIDLFEATEYYRSPRGYAPNGVNRSL
                     FSHQTVAVGWDAFHLAEVLLTQPIMVVVGDRVGAFGAYRDGCEIIGRAASKHKELVVV
                     EGYSHYDLYDKPEPVKQALDKLIPFYKTHL"
     misc_feature    complement(349954..350850)
                     /gene="ycjY"
                     /locus_tag="ECs_0332"
                     /note="Fermentation-respiration switch protein FrsA, has
                     esterase activity, DUF1100 family [Signal transduction
                     mechanisms]; Region: FrsA; COG1073"
                     /db_xref="CDD:223999"
     gene            351028..351954
                     /gene="ycaN"
                     /locus_tag="ECs_0333"
                     /db_xref="GeneID:914432"
     CDS             351028..351954
                     /gene="ycaN"
                     /locus_tag="ECs_0333"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_308360.1"
                     /db_xref="GeneID:914432"
                     /translation="MMKIEPSILPSLAWFALIVRAGSFSRAVSEMGITLAALSQNLKS
                     LEERLNTKLIYRTTRNISLTEEGQRLYEVLVSALGQIDDALKDVGDTQLEPTGLLRIN
                     SSRVAARMLVEPHIGEFLTRYPKTKIELIMDDGLSNIIADGCDVGIRLEQGLDEHMTA
                     VPVSPLIKLVTVASPDYLKEHGIPETPQELSNHNCLRLRHKSSGALSAWEFSKVVGGN
                     EEFEIEVSGKYISNDDESMIRMALNGTGIIQHLDFAIAEHINAGKLQPILEDWAVSFP
                     GFYIYVSSRVRMPSKVRAFIDFMVEKRVKLEN"
     misc_feature    351061..351231
                     /gene="ycaN"
                     /locus_tag="ECs_0333"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; Region: HTH_1; pfam00126"
                     /db_xref="CDD:425479"
     misc_feature    351310..351924
                     /gene="ycaN"
                     /locus_tag="ECs_0333"
                     /note="The C-terminal substrate binding domain of an
                     uncharacterized LysR-type transcriptional regulator
                     CrgA-like, contains the type 2 periplasmic binding fold;
                     Region: PBP2_CrgA_like_5; cd08474"
                     /db_xref="CDD:176163"
     misc_feature    order(351346..351348,351358..351360,351475..351477,
                     351517..351519,351526..351528,351727..351729,
                     351778..351780,351859..351861)
                     /gene="ycaN"
                     /locus_tag="ECs_0333"
                     /note="putative effector binding pocket [active]"
                     /db_xref="CDD:176163"
     misc_feature    order(351349..351354,351364..351369,351373..351378,
                     351385..351387,351397..351399,351403..351423,
                     351607..351609,351709..351723,351742..351747,
                     351754..351756)
                     /gene="ycaN"
                     /locus_tag="ECs_0333"
                     /note="putative dimerization interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:176163"
     gene            complement(352242..352598)
                     /locus_tag="ECs_0334"
                     /db_xref="GeneID:914433"
     CDS             complement(352242..352598)
                     /locus_tag="ECs_0334"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308361.1"
                     /db_xref="GeneID:914433"
                     /translation="MNKNLILAFALFSLPVFAEEDLGPGKYVCDIRISSLDTATQILS
                     KSATVLDNGNNFIVQMPNGDQLYSPDLENVDDGIKQKATIGGVTFIRRPTFNDRFIVE
                     DGNTGFFYKMRNCEKK"
     gene            complement(352791..353366)
                     /locus_tag="ECs_0335"
                     /db_xref="GeneID:914434"
     CDS             complement(352791..353366)
                     /locus_tag="ECs_0335"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="NP_308362.1"
                     /db_xref="GeneID:914434"
                     /translation="MQKVKLNNGIEMPLLGFGVFQMTDAAECERAVIDAINTGYRLID
                     TAASYQNEPQVGNALKQSGIARNELFVTTKLWLQDTSYEGAKAQFERSLNRLQLDYVD
                     LYLIHQPYGDVHGAWRAMEELQQAGKIRAIGVSNFHPDRLADLIAFNNVVPAVNQVEV
                     NPFNQQLHAVPWMQSRGIQPEAWAPFAVTGR"
     misc_feature    complement(<352806..353357)
                     /locus_tag="ECs_0335"
                     /note="Aldo-keto reductase (AKR) superfamily; Region:
                     AKR_SF; cl00470"
                     /db_xref="CDD:444925"
     misc_feature    complement(order(353046..353048,353145..353147,
                     353220..353222,353235..353237))
                     /locus_tag="ECs_0335"
                     /note="catalytic tetrad [active]"
                     /db_xref="CDD:381296"
     gene            353932..358185
                     /locus_tag="ECs_0336"
                     /db_xref="GeneID:914435"
     CDS             353932..358185
                     /locus_tag="ECs_0336"
                     /codon_start=1
                     /transl_table=11
                     /product="invasin"
                     /protein_id="NP_308363.1"
                     /db_xref="GeneID:914435"
                     /translation="MSRYKTGHKQPRFRYSVLARCVAWANISVQVLFPLAVTFTPVMA
                     ARAQHAVQPRLSMGNTTVTADNNVEKNVASFAANAGTFLSSQPDSDATRNFITGMATA
                     KANQEIQEWLGKYGTARVKLNVDKDFSLKDSSLEMLYPIYDTPTNMLFTQGAIHRTDD
                     RTQSNIGFGWRHFSGNDWMAGVNTFIDHDLSRSHTRIGVGAEYWRDYLKLSANGYIRA
                     SGWKKSPDIEDYQERPANGWDIRAEGYLPAWPQLGASLMYEQYYGDEVGLFGKDKRQK
                     DPHAISAEVTYTPVPLLTLSAGHKQGKSGENDTRFGLEVNYRIGEPLAKQLDTDSIRE
                     RRVLAGSRYDLVERNNNIVLEYRKSEVIRIALPERIEGKGGQTLSLGLVVSKATHGLK
                     NVQWEAPSLLAEGGKITGQGSQWQVTLPAYRPGKDNYYAISAVAYDNKGNTSKRVQTE
                     VVITGAGMSADRTALTLDGQSRIQMLANGNEQKPLVLSLRDAEGQPVTGMKDQIKTEL
                     TFKPAGNIVTRSLKATKSQAKPTLGEFTETEAGVYQSVFTTGTQSGEATITVSVDGMS
                     KTVTAELRATMMDVANSTLSANEPSGDVVADGQQAYTLTLTAVDSEGNPVTGEASRLR
                     FVPQDTNGVTVGAISEIKPGVYSAAVSSTRAGNVVVRAFSEQYQLGTLQQTLKFVAGP
                     LDAAHSSITLNPDKPVVGGTVTAIWTVKDAYDNPVTSLTPEAPSLAGAAAEGSTASGW
                     TNNGDGTWTAQITLGSTAGELEVMPKLNGQNAAANAAKVTVVADALSSNQSKVSVAED
                     HVKAGESTTVTLVAKDAHGNAISGLALSASLTGTASEGATVSSWTEKGNGSYVATLTT
                     GGKTGELRVMPLFNGQPAATEAAQLTVIAGEMSSANSTLVADNKAPTVKTTTELTFTV
                     KDAYGNPVTGLKPDAPVFSGAASTGSERPSAGNWTEKGNGVYVSTLTLGSAAGQLSVM
                     PRVNGQNAVAQPLVLNVAGDASKAEIRDMTVKVNNQLANGQSANQITLTVVDTYGNPL
                     QGQEVTLTLPQGVTSKTGNTVTTNAAGKADIELMSTVAGEHNISASVNGAQKTVTVKF
                     NADASTGQANLQVDAAAQKVANGKDAFTLTANVEDKNGNPVPGSLVTFNLPRGVKPLT
                     GDNVWVKANDEGKAELQVVSVTAGTYEITASAGNSQPSNTQTITFVADKATATVSGIE
                     VIGNYALADGNAKQTYKVTVTDANNNLLKDSEVTLTASPANLVLTPNGTAKTNEQGQA
                     IFTATTTVAAKYTLTAKVSQADGQESTKTAESKFVADDTNAVLTASSDVTSLVADGIS
                     TAKLEVTLMSANNPVGGNMWVDIKTPEGVTEKDYQFLPSKNDHFVSGKITRTFSTSKP
                     GVYTFTFNALTYGGYEMKPVTVTITAVDADTAKGEEAMN"
     misc_feature    354151..354981
                     /locus_tag="ECs_0336"
                     /note="Inverse autotransporter, beta-domain; Region:
                     IAT_beta; pfam11924"
                     /db_xref="CDD:432192"
     misc_feature    355351..355647
                     /locus_tag="ECs_0336"
                     /note="Invasin, domain 3; Region: Invasin_D3; pfam09134"
                     /db_xref="CDD:430426"
     misc_feature    355678..355953
                     /locus_tag="ECs_0336"
                     /note="Bacterial Ig-like domain (group 1); Region: BID_1;
                     smart00634"
                     /db_xref="CDD:214751"
     misc_feature    355981..356283
                     /locus_tag="ECs_0336"
                     /note="Invasin, domain 3; Region: Invasin_D3; pfam09134"
                     /db_xref="CDD:430426"
     misc_feature    <356344..356589
                     /locus_tag="ECs_0336"
                     /note="Invasin, domain 3; Region: Invasin_D3; pfam09134"
                     /db_xref="CDD:430426"
     misc_feature    356596..356904
                     /locus_tag="ECs_0336"
                     /note="Invasin, domain 3; Region: Invasin_D3; pfam09134"
                     /db_xref="CDD:430426"
     misc_feature    356956..357189
                     /locus_tag="ECs_0336"
                     /note="Bacterial Ig-like domain (group 1); Region: BID_1;
                     smart00634"
                     /db_xref="CDD:214751"
     misc_feature    357253..357495
                     /locus_tag="ECs_0336"
                     /note="Bacterial Ig-like domain (group 1); Region: BID_1;
                     smart00634"
                     /db_xref="CDD:214751"
     misc_feature    357526..357798
                     /locus_tag="ECs_0336"
                     /note="Bacterial Ig-like domain (group 1); Region: BID_1;
                     smart00634"
                     /db_xref="CDD:214751"
     gene            complement(358306..359163)
                     /gene="ykgA"
                     /locus_tag="ECs_0337"
                     /db_xref="GeneID:914436"
     CDS             complement(358306..359163)
                     /gene="ykgA"
                     /locus_tag="ECs_0337"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_308364.2"
                     /db_xref="GeneID:914436"
                     /translation="MIRQKILQQLLEWIECNLEHPISIEDIAQKSGYSRRNIQLLFRN
                     FMHVPLGEYIRKRRLCRAAILVRLTAKSMLDIAISLHFDSQQSFSREFKKLFGCSPRV
                     YRHRDYWDLANIFPSFLIRQQQKTECRLVNFPETPIFGNSFKYDIEVSNKSPDEEVKL
                     RRHHLARCMKNFKTDTYFVSTFEPSTKSVDLLTVETFAGTVCKQTDSEMPKEWTINRG
                     LYASFRYEGEWEHYPEWARNLYLMELPARGLARVNGSDIERFYYNEDFVEKDSNDVVC
                     EIFIPVRPV"
     misc_feature    complement(358315..359148)
                     /gene="ykgA"
                     /locus_tag="ECs_0337"
                     /note="MDR efflux pump AcrAB transcriptional activator
                     RobA; Region: PRK15121"
                     /db_xref="CDD:185076"
     gene            359412..360281
                     /locus_tag="ECs_0338"
                     /db_xref="GeneID:914437"
     CDS             359412..360281
                     /locus_tag="ECs_0338"
                     /codon_start=1
                     /transl_table=11
                     /product="reductase"
                     /protein_id="NP_308365.3"
                     /db_xref="GeneID:914437"
                     /translation="MEFSVLSNNLKMPMMGFGVFQVTDKNVCKQSVLNAIRTGYRLID
                     TAAVYGNEDAVGEAVREAISEGLCTREELFITSKLWVQDMLNQDTAAAGIEASLKKSG
                     LEYFDLYLLHQAMRDYFSAWRALEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKPMV
                     NQVELHPYFAQPEALATMKYYNVQPEAWAPLGGGRHKPFENNLLQSIADAHQKSISQV
                     ILRWNIQRGVVVIPKSTHQQRIEENFAIWDFSLTEKEMAQISSLDLGYVGESVKHFNP
                     EFVRGCLAVKIHD"
     misc_feature    359427..360200
                     /locus_tag="ECs_0338"
                     /note="the AKR5F family of aldo-keto reductase (AKR);
                     Region: AKR_AKR5F1; cd19133"
                     /db_xref="CDD:381359"
     misc_feature    order(359463..359471,359541..359543,359553..359558,
                     359643..359645,359745..359750,359829..359834,
                     359895..359897,359973..359993,360021..360023,
                     360057..360059,360102..360119,360126..360128,
                     360135..360140)
                     /locus_tag="ECs_0338"
                     /note="active site"
                     /db_xref="CDD:381359"
     misc_feature    order(359541..359543,359556..359558,359643..359645,
                     359745..359747)
                     /locus_tag="ECs_0338"
                     /note="catalytic tetrad [active]"
                     /db_xref="CDD:381359"
     gene            complement(360441..361034)
                     /gene="rclC"
                     /locus_tag="ECs_0340"
                     /db_xref="GeneID:914438"
     CDS             complement(360441..361034)
                     /gene="rclC"
                     /locus_tag="ECs_0340"
                     /codon_start=1
                     /transl_table=11
                     /product="reactive chlorine species stress resistance
                     inner membrane protein"
                     /protein_id="NP_308366.1"
                     /db_xref="GeneID:914438"
                     /translation="MEKYLHLLSRGDKIGLALIRLSIAIVFMWIGLLKFVPYEADSIT
                     PFVANSPLMSFFYEHPEDYKQYLTHEGEYKPEARAWQSANNTYGFSNGLGVVEVIIAL
                     LVLANPVNRWLGLLGGLMAFTTPLVTLSFLITTPEAWVPALGDAHHGFPYLSGAGRLV
                     LKDTLMLAGAVMIMADSAREILKQGSNESSSTLKTEY"
     misc_feature    complement(360483..361034)
                     /gene="rclC"
                     /locus_tag="ECs_0340"
                     /note="reactive chlorine resistance membrane protein RclC;
                     Region: chlor_memb_RclC; NF040476"
                     /db_xref="CDD:439703"
     gene            complement(361391..362716)
                     /gene="rclA"
                     /locus_tag="ECs_0342"
                     /db_xref="GeneID:914441"
     CDS             complement(361391..362716)
                     /gene="rclA"
                     /locus_tag="ECs_0342"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridine nucleotide-dependent disulfide
                     oxidoreductase of reactive chlorine stress species RCS
                     resistance"
                     /protein_id="NP_308369.2"
                     /db_xref="GeneID:914441"
                     /translation="MNKYQAVIIGFGKAGKTLAVTLAKAGWRVALIEQSNAMYGGTCI
                     NIGCIPTKTLVHDAQQHTDFVRAIQRKNEVVNFLRNKNFHNLADMPNIDVINGQAEFI
                     NNHSLRVHRPEGNLEIHGEKIFINTGAQTVVPPIPGITTTPGVYDSTGLLNLKELPGH
                     LGILGGGYIGVEFASMFANFGSKVTILEAASLFLPREERDIADNIATILRDQGVDIIL
                     NAHVERISHHENQVQVHSEHAQLAVDALLIASGRQPATASLHPENAGIAVNERGAIVV
                     DKRLHTTADNIWAMGDVTGGLQFTYISLDDYRIVRDELLGEGKRSTDDRKNVPYSVFM
                     TPPLSRVGMTEEQARESGADIQVVTLPVAAIPRARVMNDTRGVLKAIVDNKTQRILGA
                     SLLCVDSHEMINIVKMVMDAGLPYSILRDQIFTHPSMSESLNDLFSLVK"
     misc_feature    complement(361394..362716)
                     /gene="rclA"
                     /locus_tag="ECs_0342"
                     /note="pyridine nucleotide-disulfide oxidoreductase;
                     Provisional; Region: PRK08010"
                     /db_xref="CDD:181196"
     gene            362942..363796
                     /gene="rclR"
                     /locus_tag="ECs_0343"
                     /db_xref="GeneID:914442"
     CDS             362942..363796
                     /gene="rclR"
                     /locus_tag="ECs_0343"
                     /codon_start=1
                     /transl_table=11
                     /product="reactive chlorine species-specific activator of
                     the rcl genes"
                     /protein_id="NP_308370.1"
                     /db_xref="GeneID:914442"
                     /translation="MDALSRLLMLNAPQGTIDKNCVLGSDWQLPHGAGELSVIRWHAL
                     TQGAAKLEMPTGEIFTLRPGNVVLLPQNSAHRLSHVDNESTCIVCGTLRLQHSARYFL
                     TSLPETLFLAPVNHSVEYNWLREAIPFLQQESRSAMPGVDALCSQICATFFTLAVREW
                     IAQVNTEKNILSLLLHPRLGAVIQQMLEMPGHAWSVESLASIAHMSRASFAQLFRDVS
                     GTTPLAVLTKLRLQIAAQMFSREMLPVVVIAESVGYASESSFHKAFVREFGCTPGEYR
                     ERVRQLAP"
     misc_feature    362942..363793
                     /gene="rclR"
                     /locus_tag="ECs_0343"
                     /note="reactive chlorine-specific transcriptional
                     regulator RclR; Region: chlor_reg_RclR; NF040475"
                     /db_xref="CDD:439702"
     gene            364323..365042
                     /gene="ykgE"
                     /locus_tag="ECs_0344"
                     /db_xref="GeneID:914443"
     CDS             364323..365042
                     /gene="ykgE"
                     /locus_tag="ECs_0344"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich LutA family protein"
                     /protein_id="NP_308371.1"
                     /db_xref="GeneID:914443"
                     /translation="MNVNFFVTCIGDALKSRMARDSVLLLEKLGCRVNFPEKQGCCGQ
                     PAINSGYIKEAIPGMKNLIAALEDNDDPIISPAGSCTYAVKSYPTYLADEPEWASRAE
                     KVAARMQDLTSFIVNKLGVVDVGASLQGRAVYHPSCSLARKLGVKDEPLTLLKNVRGL
                     ELLTFAEQDTCCGFGGTFSVKMAEISGEMVKEKVAHLMEVRPEYLIGADVSCLLNISG
                     RLQREGQKVKVMHIAEVLMSR"
     misc_feature    <364323..365039
                     /gene="ykgE"
                     /locus_tag="ECs_0344"
                     /note="Fe-S oxidoreductase [Energy production and
                     conversion]; Region: GlpC; COG0247"
                     /db_xref="CDD:223325"
     gene            365053..366480
                     /gene="ykgF"
                     /locus_tag="ECs_0345"
                     /db_xref="GeneID:914444"
     CDS             365053..366480
                     /gene="ykgF"
                     /locus_tag="ECs_0345"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster-binding protein"
                     /protein_id="NP_308372.1"
                     /db_xref="GeneID:914444"
                     /translation="MSIKTSNTDFKTRIRQQIEDPIMRKAVANAQQRIGANRQKMVDE
                     LGLWEEWRDRAAQIRDHVLSNLDAYLYQLSEKVTQNGGHVYFAKTKEDATRYILQVAQ
                     RKNARKVVKSKSMVTEEIGVNHVLQDAGIQVIETDLGEYILQLDQDPPSHVVVPAIHK
                     DRHQIRRVLHERLGYEGPETPEAMTLFIRQKIREDFLSAEIGITGCNFAVAETGSVCL
                     VTNEGNARMCTTLPKTHIAVMGMERIAPTFAEVDVLITMLARSAVGARLTGYNTWLTG
                     PREAGHVDGPEEFHLVIVDNGRSEVLASEFRDVLRCIRCGACMNTCPAYRHIGGHGYG
                     SIYPGPIGAVISPLLGGYKDFKDLPYACSLCTACDNVCPVRIPLSKLILRHRRVMAEK
                     GITAKAEQRAIKMFAYANSHPGLWKVGMMAGAHAASWFINGGKTPLKFGAISDWMEAR
                     DLPEADGESFRSWFKKHQAQEKKNG"
     misc_feature    365104..366411
                     /gene="ykgF"
                     /locus_tag="ECs_0345"
                     /note="iron-sulfur cluster-binding protein; Region:
                     TIGR00273"
                     /db_xref="CDD:129374"
     gene            366473..367168
                     /gene="ykgG"
                     /locus_tag="ECs_0346"
                     /db_xref="GeneID:914446"
     CDS             366473..367168
                     /gene="ykgG"
                     /locus_tag="ECs_0346"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308373.2"
                     /db_xref="GeneID:914446"
                     /translation="MDNRGEFLNNVAQALGRPLRLEPQAEDAPLNNYANERLTQLNQQ
                     QRCDAFIQFASDVMLTRCELTSEAKAAEAAIRLCKELGDQSVVISGDTRLEELGISER
                     LQQECNAVVWDPAKGAKNISQAEQAKVGVVYAEYGLTESGGVVLFSAAERGRSLSLLP
                     ESSLFILRKSTLLPRVAQLAERLHQKAQAGERMPSCINIISGPSSTADIELIKVVGVH
                     GPVKAVYLIIEDC"
     misc_feature    366473..367165
                     /gene="ykgG"
                     /locus_tag="ECs_0346"
                     /note="L-lactate utilization protein LutC, contains LUD
                     domain [Energy production and conversion]; Region: LutC;
                     COG1556"
                     /db_xref="CDD:224473"
     gene            complement(367663..368079)
                     /locus_tag="ECs_0348"
                     /pseudogene="unknown"
                     /db_xref="GeneID:62676032"
     misc_feature    complement(367663..368079)
                     /locus_tag="ECs_0348"
                     /note="hypothetical protein"
                     /pseudogene="unknown"
     gene            complement(368261..368473)
                     /locus_tag="ECs_0349"
                     /db_xref="GeneID:914449"
     CDS             complement(368261..368473)
                     /locus_tag="ECs_0349"
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter"
                     /protein_id="NP_308376.2"
                     /db_xref="GeneID:914449"
                     /translation="MLRDPQLLMLWLRLGDESVNASIDGAAFRVGAGVQADITKNMGA
                     YASLDYTKGDDIENPLQGVVGINVTW"
     misc_feature    complement(368264..>368437)
                     /locus_tag="ECs_0349"
                     /note="outer membrane autotransporter barrel domain;
                     Region: autotrans_barl; TIGR01414"
                     /db_xref="CDD:273608"
     gene            complement(368427..369521)
                     /locus_tag="ECs_0350"
                     /db_xref="GeneID:914451"
     CDS             complement(368427..369521)
                     /locus_tag="ECs_0350"
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter"
                     /protein_id="NP_308377.1"
                     /db_xref="GeneID:914451"
                     /translation="MKNSKAFYRSALATAIVMALSAPAFAADNAVSTDSVTLNKDKTT
                     LDQDVVISNTADKQITAVTINAADEDLNVAFAGHDITAESTADKKFVEGVKVSGNKNV
                     VINATDSTITAQGEGTYVRTAMVIDSTGDVVVNGGNFVAKNEKGSATGISLEGAKGNN
                     VTLNGTTINAQGNKSSSNASTAIFAQKGSLLNSFEGDATDNITLAGSNIINGRIETIV
                     TAGNKTGIHTVNLNIKDGSVIGAANNKQTIYASASAQGTGSATQNLNLSVADSTIYSD
                     VLALSESENSAATTTNVNMNVARSYWEGNAYTFNSGDKAGSNLDINLSDSSVWKGKVS
                     GAGNASVSLQNESVWNVTGSSTVDALAPSG"
     gene            complement(369563..370324)
                     /gene="hyxA"
                     /locus_tag="ECs_0351"
                     /db_xref="GeneID:914452"
     CDS             complement(369563..370324)
                     /gene="hyxA"
                     /locus_tag="ECs_0351"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308378.1"
                     /db_xref="GeneID:914452"
                     /translation="MRFVLFCPSGIVPAQFAALSTGSVGNVTCIGTEEELRNKLRHRP
                     QSVVISAGRPAECAEMWFRFYRDHSFVVVLCVAPFFLPPDVSISGVLKNLRLLKPGMS
                     VEHVISIANSSGGLSGLKHAENLPVMDSYSVFMKEVNNRTKTIVMSERFPEKQKKVLS
                     LLLAGHSWEYSAQFLKTGIRQIWLAEQSLKKRWGIPDSMSLREALLLSSNKFHGDGNA
                     LEKTNAMTLRENGNTNRYSVVVNAGTQVLSLHKYK"
     gene            complement(371105..371272)
                     /gene="hyxR"
                     /locus_tag="ECs_0352"
                     /db_xref="GeneID:914453"
     CDS             complement(371105..371272)
                     /gene="hyxR"
                     /locus_tag="ECs_0352"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308379.2"
                     /db_xref="GeneID:914453"
                     /translation="MKKPLVIISACQFTRLALESLIPADRYIVRVYSNVTTEVEFVLK
                     TSCGYLLADIP"
     gene            complement(371781..372221)
                     /locus_tag="ECs_0355"
                     /pseudogene="unknown"
                     /db_xref="GeneID:62676033"
     misc_feature    complement(371781..372221)
                     /locus_tag="ECs_0355"
                     /note="invertasae"
                     /pseudogene="unknown"
     gene            372408..372542
                     /locus_tag="ECs_0356"
                     /db_xref="GeneID:62676034"
     CDS             372408..372542
                     /locus_tag="ECs_0356"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_303089.1"
                     /db_xref="GeneID:62676034"
                     /translation="MCVTSNVLVMFSSFEIFDVISYKVVFIVYLIDFICILSFNEVIV
                     "
     gene            complement(373224..374912)
                     /gene="betA"
                     /locus_tag="ECs_0357"
                     /db_xref="GeneID:914458"
     CDS             complement(373224..374912)
                     /gene="betA"
                     /locus_tag="ECs_0357"
                     /codon_start=1
                     /transl_table=11
                     /product="choline dehydrogenase"
                     /protein_id="NP_308384.1"
                     /db_xref="GeneID:914458"
                     /translation="MQFDYIIIGAGSAGNVLATRLTEDPNTSVLLLEAGGPDYRFDFR
                     TQMPAALAFPLQGKRYNWAYETEPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNAM
                     DLDNWAKEPGLENWSYLDCLPYYRKAETRDVGENDYHGGDGPVSVTTSKPGVNPLFEA
                     MIEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPQGRRASTARGYLDQAKSRPNLTIRT
                     HAMTDHIIFDCKRAVGVEWLEGDSTIPTRATANKEVLLCAGAIASPQILQRSGVGNAE
                     LLAEFDIPLVHDLPGVGENLQDHLEMYLQYECKEPVSLYPALQWWNQPKIGAEWLFGG
                     TGVGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSP
                     SRGHVRIKSRDPHQHPAILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYRGREISP
                     GTECQTDEQLDEFVRNHAETAFHPCGTCKMGYDEMSVVDGEGRVHGLEGLRVVDASIM
                     PQIITGNLNATTIMIGEKMADMIRGKEALPRSTAGYFVANGMPVRAKKMSRDLN"
     misc_feature    complement(373242..374912)
                     /gene="betA"
                     /locus_tag="ECs_0357"
                     /note="choline dehydrogenase; Validated; Region: PRK02106"
                     /db_xref="CDD:235000"
     gene            complement(374926..376398)
                     /gene="betB"
                     /locus_tag="ECs_0358"
                     /db_xref="GeneID:914459"
     CDS             complement(374926..376398)
                     /gene="betB"
                     /locus_tag="ECs_0358"
                     /codon_start=1
                     /transl_table=11
                     /product="betaine aldehyde dehydrogenase"
                     /protein_id="NP_308385.2"
                     /db_xref="GeneID:914459"
                     /translation="MSRMAEQQLYIHGGYTSATSGRTFETINPANGNVLATVQAAGRE
                     DVDRAVKSAQQGQKIWAAMTAMERSRILRRAVDILRERNDELAKLETLDTGKAYSETS
                     TVDIVTGADVLEYYAGLIPSLEGSQIPLRETSFVYTRREPLGVVAGIGAWNYPIQIAL
                     WKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGLPDGVFNVLPGVGAETGQYLTE
                     HPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIVFDDADLDLAADIAMM
                     ANFFSSGQVCTNGTRVFVPAKCNAAFEQKILARVERIRAGDVFDPQTNFGPLVSFPHR
                     DNVLRYIAKGKEEGARVLCGGDVLKGDGLDNGAWVAPTVFTDCSDEMTIVREEIFGPV
                     MSILTYESEDEVIRRANDTDYGLAAGIVTADLNRAHRVIHQLEAGICWINTWGESPAE
                     MPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMAKFQSIF"
     misc_feature    complement(374929..376398)
                     /gene="betB"
                     /locus_tag="ECs_0358"
                     /note="betaine aldehyde dehydrogenase; Provisional;
                     Region: PRK13252"
                     /db_xref="CDD:183918"
     misc_feature    complement(order(374950..374955,374959..374976,
                     375010..375012,375016..375018,375025..375027,
                     375031..375033,375043..375045,375049..375051,
                     375073..375078,375082..375093,375097..375099,
                     375106..375108,375112..375117,375124..375135,
                     375427..375429,375472..375474,375571..375576,
                     375583..375585,375592..375594,375658..375660,
                     375694..375696,375976..375984,375988..375990,
                     376012..376026,376045..376047,376057..376059,
                     376159..376161,376168..376170,376180..376182,
                     376189..376191,376201..376203,376207..376209))
                     /gene="betB"
                     /locus_tag="ECs_0358"
                     /note="tetrameric interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:143409"
     misc_feature    complement(order(375040..375042,375232..375234,
                     375238..375240,375541..375543,375637..375645,
                     375700..375702,375709..375714,375718..375720,
                     375772..375774,375871..375873,375940..375945,
                     375949..375954))
                     /gene="betB"
                     /locus_tag="ECs_0358"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:143409"
     misc_feature    complement(order(375541..375543,375550..375552,
                     375643..375645,375940..375942))
                     /gene="betB"
                     /locus_tag="ECs_0358"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143409"
     gene            complement(376412..376999)
                     /gene="betI"
                     /locus_tag="ECs_0359"
                     /db_xref="GeneID:914460"
     CDS             complement(376412..376999)
                     /gene="betI"
                     /locus_tag="ECs_0359"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="NP_308386.3"
                     /db_xref="GeneID:914460"
                     /translation="MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTG
                     IISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALPQGSAEQRLQAIVGGNFDETQVS
                     SAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFRRELPRHQAQEAGYGLAAL
                     IDGLWLRAALSGKPLDKPLAHSLTRHFITQHLPTD"
     misc_feature    complement(376418..376999)
                     /gene="betI"
                     /locus_tag="ECs_0359"
                     /note="transcriptional regulator BetI; Validated; Region:
                     PRK00767"
                     /db_xref="CDD:179115"
     gene            377128..379161
                     /gene="betT"
                     /locus_tag="ECs_0360"
                     /db_xref="GeneID:914461"
     CDS             377128..379161
                     /gene="betT"
                     /locus_tag="ECs_0360"
                     /codon_start=1
                     /transl_table=11
                     /product="choline transporter of high affinity"
                     /protein_id="NP_308387.1"
                     /db_xref="GeneID:914461"
                     /translation="MTDLSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIG
                     RTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSVKLGPEQSKPEFSLLSWAAMLFA
                     AGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA
                     LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLN
                     YGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDKGIRVLSELNVALALGLILFVL
                     FMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPVEWMNNWTLFFWAWWVAWSPFV
                     GLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHP
                     ERGFYSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDINSDAPGWL
                     RVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFFVMAGLYKSLKVEDYRRE
                     SANRDTAPRPLGLQDRLSWKKRLSRLMNYPGTRYTKQMMETVCYPAMEEVAQELRLRG
                     AYVELKSLPPEEGQQLGHLDLLVHMGEEQNFVYQIWPQQYSVPGFTYRARSGKSTYYR
                     LETFLLEGSQGNDLMDYSKEQVITDILDQYERHLNFIHLHREAPGHSVMFPDA"
     misc_feature    377128..379158
                     /gene="betT"
                     /locus_tag="ECs_0360"
                     /note="choline transport protein BetT; Provisional;
                     Region: PRK09928"
                     /db_xref="CDD:236635"
     gene            379735..383718
                     /locus_tag="ECs_0362"
                     /db_xref="GeneID:914463"
     CDS             379735..383718
                     /locus_tag="ECs_0362"
                     /codon_start=1
                     /transl_table=11
                     /product="AidA-I family adhesin"
                     /protein_id="NP_308389.1"
                     /db_xref="GeneID:914463"
                     /translation="MNKIYRLKWNRSRNCWSVCSELGSRVKGKKSRAVLISAISLYSS
                     LVFADDVIVNQDKTIDFGKENQSIDYRITVTDNANLVINATDTSRPRLTLASGGGLDI
                     TGGKVTINGPLNFLLKGTGFLNVSNAGSELYADDLYESNSGMRHDRGYFNVSNGGKIH
                     VKGTSRLTYLQGNVSGEGSQVNSETFFMGVYGSYGGNQYLSVNNGGEVNARKQISLGY
                     YDQVSDTTLAVSEGGKISAPTISLSTNSELALGAQEGSAAKAAGIIDAEKIEFVWAKT
                     SEKKITLNHTDKDATISADIVSGSEGLGYINALNGTTYLTGDNSAFSGKVKIEQNGAL
                     GITQNIGTAEINNRGKLHLKADDSMTFANKISGNGTISIDSGTVELTGNNYAFSGYID
                     VASGAVAVISEDKNIGRAELDVDGKLQINANKDWVFDNDLEGRGIVEINMGNHEFSFD
                     EFAYTDWFQGSLAFQNTTFNLEKNAEFLQKGGITAGQGSLVTVGKGAHSISTLGFSGG
                     TVDFGALTAGAQMTEGTVNVSKTLDLRGEGVIQVSDSDVVRSVSRDIDSALSLTEVDD
                     GNSTIKLVDAQGAEVLGDAGNLQLQDKNGQILSSSAQRDIQQNGQKAAVGTYDYRLTS
                     GVNNDGLYIGYGLTQLDLHATDSDALVLSSNGKSENAADLSAKITGSGDLAFSSQKGQ
                     TVSLSNKDNDYTGVTDLRSGTLLLNNDNVLGNTHELRLAAETELDMNGHSQTVGTLNG
                     SADSLLSLNGGSLTVTNGGTSTGSLTGSGELNIQGGTLDIAGDNSNLTANVNIANSAN
                     VLVSHAQGLGSANVENNGTLALNNSAEKRAAASVNYALGGNLTNNGTLMTGMSGQQAG
                     NVLVVKGNYHGNNGQLVMNTVLNGDDSVTDKLVVEGDTSGTTAVTVNNAGGTGAKTLN
                     GIELIHVDGKSEGEFVQAGRIVAGAYDYTLARGQGANSGNWYLTSGSDSPELQPEPDP
                     MPNPEPNPNPEPNPNPTPTPGPDLNVDNDLRPEAGSYIANLAAANTMFTTRLHERLGN
                     TYYTDMVTGEQKQTTMWMRHEGGHNKWRDGSGQLKTQSNRYVLQLGGDVAQWSQNGSD
                     RWHVGVMAGYGNSDSKTISSRTGYRAKASVNGYSTGLYATWYADDESRNGAYLDSWAQ
                     YSWFDNTVKGDDLQSESYKSKGFTASLEAGYKHKLAEFNGSQGTRNEWYVQPQAQVTW
                     MGVKADKHRESNGTLVHSNGDGNVQTRLGVKTWLKSHHKMDDGKSREFQPFVEVNWLH
                     NSKDFSTSMDGVSVTQDGARNIAEIKTGVEGQLNANLNVWGNVGVQVADRGYNDTSAM
                     VGIKWQF"
     misc_feature    379735..379878
                     /locus_tag="ECs_0362"
                     /note="Extended Signal Peptide of Type V secretion system;
                     Region: ESPR; pfam13018"
                     /db_xref="CDD:432938"
     misc_feature    <380014..383715
                     /locus_tag="ECs_0362"
                     /note="autotransporter barrel domain-containing
                     lipoprotein; Region: PRK14849"
                     /db_xref="CDD:184851"
     gene            383860..384948
                     /gene="yahA"
                     /locus_tag="ECs_0363"
                     /db_xref="GeneID:914464"
     CDS             383860..384948
                     /gene="yahA"
                     /locus_tag="ECs_0363"
                     /codon_start=1
                     /transl_table=11
                     /product="c-di-GMP-specific phosphodiesterase"
                     /protein_id="NP_308390.1"
                     /db_xref="GeneID:914464"
                     /translation="MASHDLSVFLEEFGATVNLTLPGIVSEKERLLLKLLMEGMSVTE
                     ISQYRNRSAKTISHQKKQLYEKLGIQSDITFWRDIFFQYHPQVISGTGNKNNFYIPDN
                     RCHHIVTPEAISLALENHEFKPWIQPVFCAQTGVLTGCEVLVRWEHPQTGIIPPDQFI
                     PLAESSGLIVIMTRQLMKQTADILMPVKHLLPDNFHIGINVSAGCFLAAGFEKECLNL
                     VKKLGNDKIKLVLELTERNPIPVTPEARAIFDSLHQHNITFALDDFGTGYATYRYLQA
                     FPVDFIKIDKSFVQMAGVDEISGHIVDNIVELARKPGLSIVAEGVETQEQADLMIGKG
                     VHFLQGYLYSPPVPGNKFISEWVMKAGG"
     misc_feature    383935..384099
                     /gene="yahA"
                     /locus_tag="ECs_0363"
                     /note="C-terminal DNA-binding domain of LuxR-like
                     proteins. This domain contains a helix-turn-helix motif
                     and binds DNA. Proteins belonging to this group are
                     response regulators; some act as transcriptional
                     activators, others as transcriptional repressors. Many...;
                     Region: LuxR_C_like; cd06170"
                     /db_xref="CDD:99777"
     misc_feature    order(383935..383943,383980..383988,384010..384015,
                     384019..384024,384028..384042,384073..384075)
                     /gene="yahA"
                     /locus_tag="ECs_0363"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     misc_feature    order(383968..383970,383974..383976,383980..383982,
                     384073..384081,384088..384090,384097..384099)
                     /gene="yahA"
                     /locus_tag="ECs_0363"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:99777"
     misc_feature    384187..384909
                     /gene="yahA"
                     /locus_tag="ECs_0363"
                     /note="Putative diguanylate phosphodiesterase; Region:
                     EAL; smart00052"
                     /db_xref="CDD:214491"
     gene            complement(384990..385921)
                     /gene="yahB"
                     /locus_tag="ECs_0364"
                     /pseudogene="unknown"
                     /db_xref="GeneID:62676035"
     misc_feature    complement(384990..385921)
                     /gene="yahB"
                     /locus_tag="ECs_0364"
                     /note="DNA-binding transcriptional regulator"
                     /pseudogene="unknown"
     gene            complement(386013..386315)
                     /gene="yahC"
                     /locus_tag="ECs_0366"
                     /db_xref="GeneID:914467"
     CDS             complement(386013..386315)
                     /gene="yahC"
                     /locus_tag="ECs_0366"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308393.1"
                     /db_xref="GeneID:914467"
                     /translation="MVWAFFAALAAGWLASVSGLSAFWASVITTVPFSAVVVWQGRFW
                     LLSFIPGGFLGMTLFFASGMNWTVTLLGFLAGNCVGIISEYGGQKLSEATTKRDGY"
     misc_feature    complement(386052..>386315)
                     /gene="yahC"
                     /locus_tag="ECs_0366"
                     /note="Protein of unknown function (DUF1097); Region:
                     DUF1097; pfam06496"
                     /db_xref="CDD:428977"
     gene            386778..387383
                     /gene="yahD"
                     /locus_tag="ECs_0367"
                     /db_xref="GeneID:914468"
     CDS             386778..387383
                     /gene="yahD"
                     /locus_tag="ECs_0367"
                     /codon_start=1
                     /transl_table=11
                     /product="ankyrin domain-containing protein"
                     /protein_id="NP_308394.1"
                     /db_xref="GeneID:914468"
                     /translation="MSIKNLPADYLLAAQQGDIDKVKTCLALGVDINTCDRQGKTAIT
                     LASLYQQYACVQALIDAGADINKQDHTCLNPFLISCLNGDLTLLRIILPAKPDLNCVT
                     RFGGVGLTPACEKGHLSIVKELLAHTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIV
                     QLLLEHGASPHLTDKYGKTPLELARERGFEEIAQLLIAAGA"
     misc_feature    <386787..387215
                     /gene="yahD"
                     /locus_tag="ECs_0367"
                     /note="Ankyrin repeat [Signal transduction mechanisms];
                     Region: ANKYR; COG0666"
                     /db_xref="CDD:223738"
     misc_feature    386892..386984
                     /gene="yahD"
                     /locus_tag="ECs_0367"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    386991..387080
                     /gene="yahD"
                     /locus_tag="ECs_0367"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    387099..387185
                     /gene="yahD"
                     /locus_tag="ECs_0367"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    order(387102..387104,387117..387125,387129..387134,
                     387144..387146,387153..387155,387183..387185,
                     387189..387191,387195..387197,387207..387212,
                     387219..387227,387246..387251,387261..387263,
                     387270..387272,387297..387299,387303..387305,
                     387309..387311,387321..387326,387333..387341,
                     387345..387350,387360..387362,387369..387371)
                     /gene="yahD"
                     /locus_tag="ECs_0367"
                     /note="oligomer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:293786"
     misc_feature    387111..387380
                     /gene="yahD"
                     /locus_tag="ECs_0367"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:432791"
     misc_feature    387189..387299
                     /gene="yahD"
                     /locus_tag="ECs_0367"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    387303..387380
                     /gene="yahD"
                     /locus_tag="ECs_0367"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     gene            387423..388286
                     /gene="yahE"
                     /locus_tag="ECs_0368"
                     /db_xref="GeneID:914469"
     CDS             387423..388286
                     /gene="yahE"
                     /locus_tag="ECs_0368"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308395.1"
                     /db_xref="GeneID:914469"
                     /translation="MWALTADADFLAQRGQGQVEQVFARAVNIALPARQQLLTLLCEE
                     YDNAPNSCRLALTHFDDLFRHGDKVQFDDQGITVGQHLHIEMSRCRRWLSPTLQMTAV
                     NFRLIAWQQWHDIIHQHLGENETLFNYRGDNPFYQALNKELHIKRRAVIQAVIDKQNI
                     ASAVASMMGLGIGLTPSADDYLTGLALILFISGHPAGKYKEEFYLGLQRGRNNTTLLS
                     AITLEAALQQRCRENIHRFIHNIIYDIPGNATQAIEKIKHIGSSSGCDMLYGMADGCA
                     LSQTYGGNYVS"
     misc_feature    387921..388247
                     /gene="yahE"
                     /locus_tag="ECs_0368"
                     /note="Protein of unknown function (DUF2877); Region:
                     DUF2877; pfam11392"
                     /db_xref="CDD:431864"
     gene            388276..389823
                     /gene="yahF"
                     /locus_tag="ECs_0369"
                     /db_xref="GeneID:914470"
     CDS             388276..389823
                     /gene="yahF"
                     /locus_tag="ECs_0369"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding succinyl-CoA synthase"
                     /protein_id="NP_308396.1"
                     /db_xref="GeneID:914470"
                     /translation="MSVKIVIKPNTYFDSVSLMSISTRANKLDGVEQAFVAMATEMNK
                     GVLKNLGLLTPELEQAKNGDLMIVINGKSGADNEQLLVEIEELFNTKAQSGSHEARYA
                     TIASAKKHIPESNLAVISVNGLFAAREARQALQNDLNVMLFSDNVSVEDELALKQLAH
                     EKGLLMMGPDCGTAIINGAALCFGNAVRRGNIGIVGASGTGSQELSVRIHEFGGGVSQ
                     LIGTGGRDLSEKIGGLMMLDAIGMLENDPQTEIIALISKPPAPAVARKVLERARACRK
                     PVVVCFLGRGETPVDEQGLQFARGTKEAALKAVMLSGVKQEHLDLHTLNQPLITDVRA
                     RLKPQQKYIRGLFCGGTLCDETMFAVMEKHSDVYSNIQPDPEFRLKDINRSIKHTFLD
                     FGDDDFTNGKPHPMIDPTNRISRLIEEARDPEVAVIVMDFVLGFGSHEDPVGSTIEAI
                     KEAKAIAAAEGRELIILAYVLGTDLDTPSLEQQSQMLLDAGVILASSSTNTGLLAREF
                     ICKGEEA"
     misc_feature    388291..389802
                     /gene="yahF"
                     /locus_tag="ECs_0369"
                     /note="membrane protein FdrA; Validated; Region: PRK06091"
                     /db_xref="CDD:180395"
     gene            389823..391241
                     /gene="yahG"
                     /locus_tag="ECs_0370"
                     /db_xref="GeneID:914471"
     CDS             389823..391241
                     /gene="yahG"
                     /locus_tag="ECs_0370"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308397.1"
                     /db_xref="GeneID:914471"
                     /translation="MSQSLFSQPLNVINVGIAMFSDDLKKQHVEVTQFDWTPPGQGNM
                     QVVQALDNIADSPLADKIAAANQQALERIIQSHPVLIGFDQAINVVPGMTPKTILHAG
                     PPITWEKMCGAMKGAVTGALVFEGLAKDLDEAAELAASGEITFSPCHEHDCVGSMAGV
                     TSASMFMHIVKNKTYGNIAYTNMSEQMAKILRMGANDQSVIDRLNWMRDVQGPILRDA
                     MKIIGEIDLRLMLAQALHMGDECHNRNNAGTTLLIQALTPGIIQAGYSVAQQREVFEF
                     VASSDYFSGPTWMAMCKAAMDAAHGIEYSTVVTTMARNGVEFGLRVSGLPGQWFTGPA
                     QQVIGPMFAGYKPEDSGLDIGDSAITETYGIGGFAMATAPAIVALVGGTVEEAIDFSR
                     QMREITLGENPNVTIPLLGFMGVPSAVDITRVGSSGILPVINTAIAHKDAGVGMIGAG
                     IVHPPFACFEKAILGWCERYGV"
     misc_feature    <389856..389972
                     /gene="yahG"
                     /locus_tag="ECs_0370"
                     /note="membrane protein FdrA; Validated; Region: PRK06091"
                     /db_xref="CDD:180395"
     misc_feature    390249..390893
                     /gene="yahG"
                     /locus_tag="ECs_0370"
                     /note="Protein of unknown function (DUF1116); Region:
                     DUF1116; pfam06545"
                     /db_xref="CDD:428999"
     gene            391267..391587
                     /gene="yahH"
                     /locus_tag="ECs_0371"
                     /db_xref="GeneID:914472"
     CDS             391267..391587
                     /gene="yahH"
                     /locus_tag="ECs_0371"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308398.1"
                     /db_xref="GeneID:914472"
                     /translation="MNALSGLRMAQESVGLISVAHQAFVTIAGCGVNALSGLQVAQEF
                     VGLISVAHQAFITIAGCGVNALSGLRMAQESVGLISVAHQAFVTIAGCGVNALSGLRM
                     AREL"
     gene            391756..392706
                     /gene="yahI"
                     /locus_tag="ECs_0372"
                     /db_xref="GeneID:914473"
     CDS             391756..392706
                     /gene="yahI"
                     /locus_tag="ECs_0372"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="NP_308399.1"
                     /db_xref="GeneID:914473"
                     /translation="MKELVVVAIGGNSIIKDNASQSIEHQAEAVKAVADTVLEMLASD
                     YDIVLTHGNGPQVGLDLRRAEIAHEREGLPLTPLANCVADTQGGIGYLIQQALNNRLA
                     RHGEKKAVTVVTQVEVDKNDPGFAHPTKPIGAFFSESQRDELQKANPDWRFVEDAGRG
                     YRRVVASPEPKRIVEAPAIKALIQQGFVVIGAGGGGIPVVRTDAGDYQSVDAVIDKDL
                     STALLAREIHADILVITTGVEKVCIHFGKPEKQALDRVDIATMTRYMQEGHFPPGSML
                     PKIIASLTFLEQGGKEVIITTPECLPAALRGETGTHIIKT"
     misc_feature    391756..392703
                     /gene="yahI"
                     /locus_tag="ECs_0372"
                     /note="putative carbamate kinase; Reviewed; Region:
                     PRK12352"
                     /db_xref="CDD:183464"
     misc_feature    order(391777..391779,391783..391788,391909..391917,
                     392143..392145,392398..392406)
                     /gene="yahI"
                     /locus_tag="ECs_0372"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:239768"
     misc_feature    order(391786..391788,392461..392466,392479..392481,
                     392488..392490,392563..392565,392575..392580,
                     392587..392589)
                     /gene="yahI"
                     /locus_tag="ECs_0372"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239768"
     misc_feature    order(391786..391788,392461..392466,392479..392481,
                     392488..392490,392563..392565,392575..392580,
                     392587..392589)
                     /gene="yahI"
                     /locus_tag="ECs_0372"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239768"
     misc_feature    order(391939..391941,391981..391983,391990..391995,
                     392002..392004,392014..392019,392026..392028,
                     392035..392040,392050..392052,392086..392094,
                     392098..392100,392278..392280,392287..392289,
                     392374..392376,392380..392382)
                     /gene="yahI"
                     /locus_tag="ECs_0372"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:239768"
     gene            392716..394098
                     /gene="yahJ"
                     /locus_tag="ECs_0373"
                     /db_xref="GeneID:914474"
     CDS             392716..394098
                     /gene="yahJ"
                     /locus_tag="ECs_0373"
                     /codon_start=1
                     /transl_table=11
                     /product="metallo-dependent hydrolase domain deaminase"
                     /protein_id="NP_308400.1"
                     /db_xref="GeneID:914474"
                     /translation="MKENNSRREFLSQSGKMVTAAALFGTSVPLAHAAVSGTTNCEAN
                     NTMKITDPHYYLDNVLLETGFDYENGVAVQTRTARQTVEIQNGKIVALRENKQHPDAT
                     LPHYDAGDKLMLPTTRDMHIHLDKTFYGGPWRSLNRPAGTTIQDMIKLEQKMLPELQP
                     YTQERAEKLIDLLQSKGTTIARSHCNIEPVSGLKNLQNLQAVLARRQAGFECEIVAFP
                     QHGLLLSKSEPLMREAMQAGAHYVGGLDPTSVDGAMEKSLDTMFQIALDYDKGVDIHL
                     HETTPSGVAAINYMVETVEKTPQLKGKLTISHAFALATLNEQQVDELAHRMAAQQISI
                     ASTVPIGTLHMPLKQLHDKGVKVMTGTDSVIDHWSPYGLGDMLEKANLYAQLYIRPNE
                     QNLSRSLFLATGDVLPLNEKGERVWPKAQDDASFVLVDASCSAEAVARISPRTATFHK
                     GQLVWGSVAG"
     misc_feature    392860..394095
                     /gene="yahJ"
                     /locus_tag="ECs_0373"
                     /note="putative deaminase; Validated; Region: PRK06846"
                     /db_xref="CDD:235873"
     misc_feature    order(393076..393078,393082..393084,393538..393540,
                     393547..393549,393637..393639,393799..393801)
                     /gene="yahJ"
                     /locus_tag="ECs_0373"
                     /note="active site"
                     /db_xref="CDD:238618"
     gene            394397..394807
                     /locus_tag="ECs_5377"
                     /db_xref="GeneID:62676036"
     CDS             394397..394807
                     /locus_tag="ECs_5377"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_009502591.1"
                     /db_xref="GeneID:62676036"
                     /translation="MTIKEKFSQKYPHASFCTFGDSAALADHLATLIATGVKTASCGS
                     LAGCIEDNAFPMIGEYKIVENSRGEPVCVIRVIGLHLLRFSDVTAELARKEGEGDLSL
                     EYWRNEHRRFFQAEGSYSPEMDVIFEEYALIDVV"
     misc_feature    394397..394801
                     /locus_tag="ECs_5377"
                     /note="Predicted RNA-binding protein YhfF, contains
                     PUA-like ASCH domain [General function prediction only];
                     Region: YhfF; COG4405"
                     /db_xref="CDD:226838"
     gene            395058..396044
                     /locus_tag="ECs_0374"
                     /db_xref="GeneID:914475"
     CDS             395058..396044
                     /locus_tag="ECs_0374"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="NP_308401.1"
                     /db_xref="GeneID:914475"
                     /translation="MMNKRFVINMVSSLLLGAALISAPLQAAEKVVVNISKVDGMPWF
                     NRMGEGVVEAGKAFGVNASQVGPSSTDAPQQVKIIEDLIARKVNAITIVPNDANVLEP
                     VFKKARDAGIVVLTNESPGQPSANWDIEIIDNEKFAAEYVEHMAKRMGGKGGYVIYVG
                     SLTVPQHNLWADLLVKYQKEHYPDMHEVTRRMPVAESVDVSRRTTLDLMKTYPDLKAV
                     VSFGSNGPIGAGRAVKEKRAKNKVAVYGMMIPSQAASLIKSGDITEGITYDPASAGYA
                     LAAVASTLLKGEEIKPGLEMQNLGKADVDMDKRIIRFHKVLLVNKDNIDSLY"
     misc_feature    395151..396032
                     /locus_tag="ECs_0374"
                     /note="ligand-binding protein LsrB-like of ABC transporter
                     periplasmic binding protein; Region:
                     PBP1_LsrB_Quorum_Sensing-like; cd20002"
                     /db_xref="CDD:380657"
     misc_feature    order(395166..395168,395184..395189,395409..395411,
                     395448..395450,395553..395558,395565..395567,
                     395718..395726,395796..395798,395856..395861)
                     /locus_tag="ECs_0374"
                     /note="putative ligand binding site [chemical binding];
                     other site"
                     /db_xref="CDD:380657"
     gene            396399..397577
                     /locus_tag="ECs_0375"
                     /db_xref="GeneID:914476"
     CDS             396399..397577
                     /locus_tag="ECs_0375"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding component of sugar ABC transporter"
                     /protein_id="NP_308402.2"
                     /db_xref="GeneID:914476"
                     /translation="MNHYHHGLFVNRRRLREVAQAAMTSINVTLPLDTLVSELSIARC
                     QLVAICRALAQDARLIVMDEPTASLTHQEVQGLLQVVHQLRERGICVVFVSHRLEEVM
                     EVSDRISVLKDGELVGTFPAAEMTTKQLGFLMTGQEFEYQVRELWQGKSSTPVLEVRN
                     LSRHGEYLNINLRVEAGEVVSIVGLLGAGRTELCLSLFGMTRPDAGEILINGQLVTLH
                     SNQDAIRHGIGYVSEDRMSRGLVMAQSIEDNIISTVFHKVKDRFGFLSETKVRDLVDR
                     LIKALTIKVSDPHLPVNTLSGGNAQRVSIAKWLAIGPRLLILDSPTVGVDIANKAGIY
                     GIISDLAAHGIAVLMICDEIEEAWYQSHRILVMQKGQITHSFLPDSSSQARIAEVVNG
                     "
     misc_feature    <396423..397574
                     /locus_tag="ECs_0375"
                     /note="ABC-type sugar transport system, ATPase component
                     [Carbohydrate transport and metabolism]; Region: MglA;
                     COG1129"
                     /db_xref="CDD:224053"
     gene            397570..398541
                     /locus_tag="ECs_0377"
                     /db_xref="GeneID:914478"
     CDS             397570..398541
                     /locus_tag="ECs_0377"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="NP_308404.1"
                     /db_xref="GeneID:914478"
                     /translation="MAELKKRHEFWLALLIVVLFVGLAWRSDEFLTFGNLYDLANNYA
                     MLTILACGLFVVLISGGIDISFPAMTIIAQYGMVLLLQKIGGNFAVAFALAGCIGILL
                     GLINALLVNRLRVPSIIITISTLNIFYGLLLWLSKGVWLYDFPPWFEQGVMLFKYTDA
                     DGYDYGLGLPLIAMITVVLLTAFIMNFTSVGRKIYALGGNRESASRIGFSVLKLQLFV
                     YGYMGLMSGAAGVVQSWTVMTVAPDSLLGYELTVLAAVVLGGTSLLGGRGTLTGTLLG
                     VVLLAVMQNGLNLLGVSSYWQTLITGIIIVASISATAWSQHQNRSLL"
     misc_feature    397579..398529
                     /locus_tag="ECs_0377"
                     /note="Ribose/xylose/arabinose/galactoside ABC-type
                     transport system, permease component [Carbohydrate
                     transport and metabolism]; Region: AraH; COG1172"
                     /db_xref="CDD:224093"
     gene            398538..399494
                     /locus_tag="ECs_0378"
                     /db_xref="GeneID:914479"
     CDS             398538..399494
                     /locus_tag="ECs_0378"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="NP_308405.1"
                     /db_xref="GeneID:914479"
                     /translation="MKKSWRNNVEFYLIGLLVLTVAAFSITMPEIFWSISNFQSVASQ
                     MPVLGILALAMAVTMLCGGINLSIIATANACSLVMAWVATQYPPGIATVVATLLAGAG
                     AAVIIGLCNGVLIAGIRVLPILATLGMMTLLKGINILVTGGSAIANYPSWVLWLNHAQ
                     WFGIPLPMWLFAAVALGLWILLEKTPLGKAIYLIGSNERATLYSGINTRRVLIWVYVI
                     SALLCAVAAFLMMSKLNSAKASYGESYLLVSILAAVLGGVNPDGGSGRIIGMVLALFL
                     LQIIESGFNILGISPYLTMALWGTLLLCFIQARGMLGLDRVV"
     misc_feature    398538..399476
                     /locus_tag="ECs_0378"
                     /note="Ribose/xylose/arabinose/galactoside ABC-type
                     transport system, permease component [Carbohydrate
                     transport and metabolism]; Region: AraH; COG1172"
                     /db_xref="CDD:224093"
     gene            399581..400630
                     /gene="yahK"
                     /locus_tag="ECs_0379"
                     /db_xref="GeneID:914480"
     CDS             399581..400630
                     /gene="yahK"
                     /locus_tag="ECs_0379"
                     /codon_start=1
                     /transl_table=11
                     /product="broad specificity NADPH-dependent aldehyde
                     reductase"
                     /protein_id="NP_308406.1"
                     /db_xref="GeneID:914480"
                     /translation="MKIKAVGSYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDL
                     HQVRSEWAGTVYPCVPGHEIVGRVVAVGDQVEKHAPGDLVGVGCIVDSCKHCEECEDG
                     LENYCDHMTGTYNSPTPDEPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAG
                     ITTYSPLRHWQAGPGKKVGVVGIGGLGHMGIKLAHAMGAHVVAFTTSEAKREAAKALG
                     ADEVVNSRNADEMAAHLKSFDFILNTVAAPHNLDDFTTLLKRDGTMTLVGAPATPHKS
                     PEVFNLIMKRRAIAGSMIGGIPETQEMLDFCAEHGIVADIEMIRADQINEAYERMLRG
                     DVKYRFVIDNRTLTD"
     misc_feature    399608..400609
                     /gene="yahK"
                     /locus_tag="ECs_0379"
                     /note="Cinnamyl alcohol dehydrogenases (CAD); Region:
                     CAD1; cd05283"
                     /db_xref="CDD:176186"
     misc_feature    order(399698..399706,399713..399715,400052..400054,
                     400064..400066,400124..400141,400193..400198,
                     400208..400210,400253..400255,400310..400315,
                     400319..400321,400379..400384,400454..400462)
                     /gene="yahK"
                     /locus_tag="ECs_0379"
                     /note="putative NAD(P) binding site [chemical binding];
                     other site"
                     /db_xref="CDD:176186"
     misc_feature    order(399698..399700,399704..399706,399764..399766,
                     399842..399844,400052..400054,400460..400462)
                     /gene="yahK"
                     /locus_tag="ECs_0379"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:176186"
     misc_feature    order(399698..399700,399764..399766,400052..400054)
                     /gene="yahK"
                     /locus_tag="ECs_0379"
                     /note="catalytic Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176186"
     misc_feature    order(399857..399859,399866..399868,399875..399877,
                     399899..399901)
                     /gene="yahK"
                     /locus_tag="ECs_0379"
                     /note="structural Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176186"
     misc_feature    order(399896..399898,400073..400075,400085..400087,
                     400361..400363,400376..400384,400388..400390,
                     400418..400420,400424..400429,400436..400459)
                     /gene="yahK"
                     /locus_tag="ECs_0379"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:176186"
     gene            400873..401688
                     /gene="yahL"
                     /locus_tag="ECs_0380"
                     /db_xref="GeneID:914481"
     CDS             400873..401688
                     /gene="yahL"
                     /locus_tag="ECs_0380"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308407.1"
                     /db_xref="GeneID:914481"
                     /translation="MISLKAPHNNLMPYTQQSILNTVKNNQLPEDIKSSLVSCVDIFK
                     VLIKQYYDYPYDCRDDLVDDDKLIHLMAAVRDCEWSDDNALTINVQFNDFPGFYDWMD
                     YPDHPVKFVFRILENQKGTVWVYDQDDAFLDIKANVQAGRFTGLKKLVQFINSVRTDC
                     KCILLEHHMPLLRLFPKGKECMHVEKWLREMSSIPETDAPIKQALAHGLLLHLKNIYP
                     VFPESLVMLLLSVLDVKTYRDDARLNEGISNRVQELGDRYYPVNKHVKIRYTL"
     gene            complement(402366..402998)
                     /gene="yahN"
                     /locus_tag="ECs_0382"
                     /db_xref="GeneID:914484"
     CDS             complement(402366..402998)
                     /gene="yahN"
                     /locus_tag="ECs_0382"
                     /codon_start=1
                     /transl_table=11
                     /product="neutral amino-acid efflux system"
                     /protein_id="NP_308409.4"
                     /db_xref="GeneID:914484"
                     /translation="MDPLHAVYLTVGLFVITFFNPGANLFVVVQTSLASGRRAGVLTG
                     LGVALGDAFYSGLGLFGLATLITQCEEIFSLIRIVGGAYLLWFAWCSMRRQSTPQMST
                     LQQPINAPWYVFFRRGLITDLSNPQTVLFFISIFSVTLNAETPTWARLMAWAGIVLAS
                     IIWRVFLSQAFSLPAVRRAYGRMQRVASRVIGAIIGVFALRLIYEGVTQR"
     misc_feature    complement(402393..402941)
                     /gene="yahN"
                     /locus_tag="ECs_0382"
                     /note="The Resistance to Homoserine/Threonine (RhtB)
                     Family protein; Region: 2A76; TIGR00949"
                     /db_xref="CDD:273358"
     gene            403184..403459
                     /gene="yahO"
                     /locus_tag="ECs_0383"
                     /db_xref="GeneID:914485"
     CDS             403184..403459
                     /gene="yahO"
                     /locus_tag="ECs_0383"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308410.1"
                     /db_xref="GeneID:914485"
                     /translation="MKIISKMLVGALAFAVTNVYAAELMTKAEFEKVESQYEKIGDIS
                     TSNEMSTADAKEDLIKKADEKGADVLVLTSGQTDNKIHGTADIYKKK"
     misc_feature    403184..403456
                     /gene="yahO"
                     /locus_tag="ECs_0383"
                     /note="hypothetical protein; Provisional; Region:
                     PRK09929"
                     /db_xref="CDD:182151"
     gene            complement(403557..405143)
                     /gene="prpR"
                     /locus_tag="ECs_0384"
                     /db_xref="GeneID:914486"
     CDS             complement(403557..405143)
                     /gene="prpR"
                     /locus_tag="ECs_0384"
                     /codon_start=1
                     /transl_table=11
                     /product="propionate catabolism operon regulatory protein"
                     /protein_id="NP_308411.1"
                     /db_xref="GeneID:914486"
                     /translation="MAHPPRLNDDKPVIWTVSVTRLFELFRDISLEFDHLANITPIQL
                     GFEKAVTYIRKKLANERCDAIIAAGSNGAYLKSRLSVPVILIKPSGYDVLQALAKAGK
                     LTSSIGVVTYQETIPALVAFQKTFNLRLDQRSYITEEDARGQINELKANGTEAVVGAG
                     LITDLAEEAGMTGIFIYSAATVRQAFSDALDMTRMSLRHNTHDATRNALRTRYVLGDM
                     LGQSPQMEQVRQTILLYARSSAAVLIEGETGTGKELAAQAIHREYFARHDARQGKKSH
                     PFVAVNCGAIAESLLEAELFGYEEGAFTGSRRGGRAGLFEIAHGGTLFLDEIGEMPLP
                     LQTRLLRVLEEKEVTRVGGHQPVPVDVRVISATHCNLEEDMRQGQFRRDLFYRLSILR
                     LQLPPLRERVADILPLAESFLKVSLAALSAPFSAALRQGLQASETVLVHYDWPGNIRE
                     LRNMMERLALFLSVEPTPDLTPQFLQLLLPELARESAKIPAPRLLTPQQALEKFNGDK
                     TAAANYLGISRTTFWRRLKS"
     misc_feature    complement(403560..405143)
                     /gene="prpR"
                     /locus_tag="ECs_0384"
                     /note="propionate catabolism operon regulatory protein
                     PrpR; Provisional; Region: PRK15424"
                     /db_xref="CDD:237963"
     gene            405382..406272
                     /gene="prpB"
                     /locus_tag="ECs_0385"
                     /db_xref="GeneID:914487"
     CDS             405382..406272
                     /gene="prpB"
                     /locus_tag="ECs_0385"
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylisocitrate lyase"
                     /protein_id="NP_308412.1"
                     /db_xref="GeneID:914487"
                     /translation="MSLHSPGKAFRAALTKENPLQIVGTINANHALLAQRAGYQAIYL
                     SGGGVAAGSLGLPDLGISTLDDVLTDIRRITDVCSLPLLVDADIGFGSSAFNVARTVK
                     SMIKAGAAGLHIEDQVGAKRCGHRPNKAIVSKEEMVDRIRAAVDAKTDPDFVIMARTD
                     ALAVEGLDAAIERAQAYVEAGAEMLFPEAITELAMYRQFADAVQVPILANITEFGATP
                     LFTTDELRSAHVAMALYPLSAFRAMNRAAEHVYNVLRQEGTQKSVIDTMQTRNELYES
                     INYYHYEEKLDDLFVRSQAK"
     misc_feature    405385..406251
                     /gene="prpB"
                     /locus_tag="ECs_0385"
                     /note="2-methylisocitrate lyase; Provisional; Region:
                     prpB; PRK11320"
                     /db_xref="CDD:183086"
     gene            406428..407597
                     /gene="prpC"
                     /locus_tag="ECs_0386"
                     /db_xref="GeneID:914488"
     CDS             406428..407597
                     /gene="prpC"
                     /locus_tag="ECs_0386"
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate synthase"
                     /protein_id="NP_308413.1"
                     /db_xref="GeneID:914488"
                     /translation="MSDTTILQNSTHVIKPKKSVALSGVPAGNTALCTVGKSGNDLHY
                     RGYDILDLAEHCEFEEVAHLLIHGKLPTRDELAAYKTKLKALRGLPANVRTVLEALPA
                     ASHPMDVMRTGVSALGCTLPEKEGHTVSGARDIADKLLASLSSILLYWYHYSHNGERI
                     QPETDDDSIGGHFLHLLHGEKPSQSWEKAMHISLVLYAEHEFNASTFTSRVIAGTGSD
                     MYSAIIGAIGALRGPKHGGANEVSLEIQQRYETPDEAEADIRKRVESKEVVIGFGHPV
                     YTIADPRHQVIKRVAKQLSQEGGSLKMYNIADRLETVMWESKKMFPNLDWFSAVSYNM
                     MGVPTEMFTPLFVIARVTGWAAHIIEQRQDNKIIRPSANYVGPEDRQFVALDKRQ"
     misc_feature    406470..407591
                     /gene="prpC"
                     /locus_tag="ECs_0386"
                     /note="methylcitrate synthase; Provisional; Region:
                     PRK12351"
                     /db_xref="CDD:183463"
     misc_feature    order(406485..406493,406500..406514,406698..406703,
                     406710..406715,406737..406739,406749..406751,
                     406761..406763,406770..406772,406914..406916,
                     407025..407039,407046..407051,407061..407063,
                     407070..407081,407088..407090,407109..407114,
                     407118..407129,407250..407252,407523..407555)
                     /gene="prpC"
                     /locus_tag="ECs_0386"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:99870"
     misc_feature    order(406494..406496,407025..407027,407034..407036,
                     407127..407135,407139..407141,407148..407150,
                     407229..407252,407259..407261,407274..407276,
                     407379..407381,407385..407387,407394..407396,
                     407400..407402,407463..407465,407475..407477,
                     407523..407525,407532..407534)
                     /gene="prpC"
                     /locus_tag="ECs_0386"
                     /note="active site"
                     /db_xref="CDD:99870"
     misc_feature    order(406494..406496,407025..407027,407034..407036,
                     407127..407132,407229..407234,407238..407252,
                     407274..407276,407394..407396,407475..407477)
                     /gene="prpC"
                     /locus_tag="ECs_0386"
                     /note="citrylCoA binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:99870"
     misc_feature    order(407025..407027,407034..407036,407130..407135,
                     407247..407249,407274..407276,407400..407402,
                     407463..407465,407475..407477,407532..407534)
                     /gene="prpC"
                     /locus_tag="ECs_0386"
                     /note="oxalacetate/citrate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:99870"
     misc_feature    order(407127..407132,407139..407141,407148..407150,
                     407229..407246,407250..407252,407259..407261,
                     407379..407381,407385..407387,407394..407396,
                     407400..407402,407523..407525)
                     /gene="prpC"
                     /locus_tag="ECs_0386"
                     /note="coenzyme A binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:99870"
     misc_feature    order(407130..407132,407247..407249,407400..407402)
                     /gene="prpC"
                     /locus_tag="ECs_0386"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:99870"
     gene            407631..409082
                     /gene="prpD"
                     /locus_tag="ECs_0387"
                     /db_xref="GeneID:914489"
     CDS             407631..409082
                     /gene="prpD"
                     /locus_tag="ECs_0387"
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate dehydratase"
                     /protein_id="NP_308414.1"
                     /db_xref="GeneID:914489"
                     /translation="MSAQINNIRPEFDREIVDIVDYVMNYEISSKVAYDTAHYCLLDT
                     LGCGLEALEYPACKKLLGPIVPGTVVPNGVRVPGTQFQLDPVQAAFNIGAMIRWLDFN
                     DTWLAAEWGHPSDNLGGILATADWLSRNAVASGKAPLTMKQVLTGMIKAHEIQGCIAL
                     ENSFNRVGLDHVLLVKVASTAVVAEMLGLTREEILNAVSLAWVDGQSLRTYRHAPNTG
                     TRKSWAAGDATSRAVRLALMAKTGEMGYPSALTAPVWGFYDVSFKGESFRFQRPYGSY
                     VMENVLFKISFPAEFHSQTAVEAAMTLYEQMQAAGKTAADIEKVSIRTHEACIRIIDK
                     KGPLNNPADRDHCIQYMVAIPLLFGRLTAADYEDNVAQDKRIDALREKINCFEDPVFT
                     ADYHDPEKRAIANAITLEFTDGTRFEEVVVEYPIGHARRRQDGIPKLVDKFKINLARQ
                     FPTRQQQRILEVSLDRARLEQMPVNEYLDLYVI"
     misc_feature    407631..409079
                     /gene="prpD"
                     /locus_tag="ECs_0387"
                     /note="bifunctional 2-methylcitrate dehydratase/aconitate
                     hydratase; Region: prpD; PRK09425"
                     /db_xref="CDD:181845"
     gene            409122..411008
                     /gene="prpE"
                     /locus_tag="ECs_0388"
                     /db_xref="GeneID:914490"
     CDS             409122..411008
                     /gene="prpE"
                     /locus_tag="ECs_0388"
                     /codon_start=1
                     /transl_table=11
                     /product="propionate--CoA ligase"
                     /protein_id="NP_308415.1"
                     /db_xref="GeneID:914490"
                     /translation="MSFSEFYQRSINEPEQFWAEQARRIDWQTPFTQTLDHSNPPFAR
                     WFCEGRTNLCHNAIDRWLEKQPEALALIAVSSETEEERTFTFRQLHDEVNAVASMLRS
                     LGVQRGDRVLVYMPMIAEAHITLLACARIGAIHSVVFGGFASHSVAARIDDAKPVLIV
                     SADAGARGGKIIPYKKLLDDAISQAQHQPRHVLLVDRGLAKMARVSGRDVDFASLRHQ
                     HIGARVPVAWLESNETSCILYTSGTTGKPKGVQRDVGGYAVALATSMDTIFGGKAGGV
                     FFCASDIGWVVGHSYIVYAPLLAGMATIVYEGLPTWPDCGVWWKIVEKYQVSRMFSAP
                     TAIRVLKKFPTAEIRKHDLSSLEVLYLAGEPLDEPTASWVSNTLDVPVIDNYWQTESG
                     WPIMAIARGLDDRPTRLGSPGVPMYGYNVQLLNEVTGEPCGVNEKGMLVVEGPLPPGC
                     IQTIWGDDDRFVKTYWSLFSRPVYATFDWGIRDADGYHFILGRTDDVINVAGHRLGTR
                     EIEESISSHPGVAEVAVVGVKDALKGQVAVAFVIPKESDSLEDRDVAHSQEKAIMALV
                     DSQIGNFGRPAHVWFVSQLPKTRSGKMLRRTIQAICEGRDPGDLTTIDDPASLNQIRQ
                     AMEE"
     misc_feature    409122..411005
                     /gene="prpE"
                     /locus_tag="ECs_0388"
                     /note="propionyl-CoA synthetase; Provisional; Region:
                     prpE; PRK10524"
                     /db_xref="CDD:182517"
     gene            411902..413161
                     /gene="codB"
                     /locus_tag="ECs_0389"
                     /db_xref="GeneID:914491"
     CDS             411902..413161
                     /gene="codB"
                     /locus_tag="ECs_0389"
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine transporter"
                     /protein_id="NP_308416.1"
                     /db_xref="GeneID:914491"
                     /translation="MSQDNNFSQGPVPQSARKGVLALTFVMLGLTFFSASMWTGGTLG
                     TGLSYHDFFLAVLIGNLLLGIYTSFLGYIGAKTGLTTHLLARFSFGVKGSWLPSLLLG
                     GTQVGWFGVGVAMFAIPVGKATGLDINLLIAVSGLLMTVTVFFGISALTVLSLIAVPA
                     IACLGGYSVWLAVNGMGGLDALKAVVPAQPLDFNVALALVVGSFISAGTLTADFVRFG
                     RNAKLAVLVAMVAFFLGNSLMFIFGAAGAAALGMADISDVMIAQGLLLPAIVVLGLNI
                     WTTNDNALYASGLGFANITGMSSKTLSVINGIIGTVCALWLYNNFVGWLTFLSAAIPP
                     VGGVIIADYLMNRRRYEHFATTRMMSVNWVAILAVALGIAAGHWLPGIVPVNAVLGGA
                     LSYLILNPILNRKTTAAMTHVEANSVE"
     misc_feature    411926..413134
                     /gene="codB"
                     /locus_tag="ECs_0389"
                     /note="cytosine permease; Provisional; Region: codB;
                     PRK11017"
                     /db_xref="CDD:236821"
     misc_feature    order(411986..411988,411995..411997,412724..412726,
                     412733..412738)
                     /gene="codB"
                     /locus_tag="ECs_0389"
                     /note="Na binding site [ion binding]; other site"
                     /db_xref="CDD:271377"
     misc_feature    order(411998..412000,412223..412225,412235..412237,
                     412508..412513,412517..412519,412739..412741,
                     412751..412753)
                     /gene="codB"
                     /locus_tag="ECs_0389"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:271377"
     gene            413151..414434
                     /gene="codA"
                     /locus_tag="ECs_0390"
                     /db_xref="GeneID:914492"
     CDS             413151..414434
                     /gene="codA"
                     /locus_tag="ECs_0390"
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine/isoguanine deaminase"
                     /protein_id="NP_308417.1"
                     /db_xref="GeneID:914492"
                     /translation="MSNNALQTIINARLPGKEGLWQIHLQDGKISAIDAQSGVMPITE
                     NSLDAEQGLVIPPFVEPHIHLDTTQTAGQPNWNQSGTLFEGIERWAERKALLTHDDVK
                     QRAWQTLKWQIANGIQHVRTHVDVSDATLTALKAMLEVKLEVAPWIDLQIVAFPQEGI
                     LSYPNGEALLEEALRLGADVVGAIPHFEFTREYGVESLHKTFALAQKYDRLIDVHCDE
                     IDDEQSRFVETVAALAHREGMGARVTASHTTAMHSYNGAYTSRLFRLLKMSGINFVAN
                     PLVNIHLQGRFDTYPKRRGITRVKEMLESGINVCFGHDDVFDPWYPLGTANMLQVLHM
                     GLHVCQLMGYGQINDGLNLITHHSARTLNLQDYSIAAGNSANLIILPAENGFDALRRQ
                     VPVRYSVRGGKVIASTQPAQTTVYLEQPEAIDYKR"
     misc_feature    413154..414431
                     /gene="codA"
                     /locus_tag="ECs_0390"
                     /note="cytosine deaminase; Provisional; Region: PRK09230"
                     /db_xref="CDD:181713"
     misc_feature    order(413334..413336,413340..413342,413793..413795,
                     413802..413804,413889..413891,414090..414092)
                     /gene="codA"
                     /locus_tag="ECs_0390"
                     /note="active site"
                     /db_xref="CDD:238618"
     gene            complement(414567..415466)
                     /gene="cynR"
                     /locus_tag="ECs_0391"
                     /db_xref="GeneID:914493"
     CDS             complement(414567..415466)
                     /gene="cynR"
                     /locus_tag="ECs_0391"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator of cyn operon"
                     /protein_id="NP_308418.1"
                     /db_xref="GeneID:914493"
                     /translation="MLSRHINYFLAVAEHGSFTRAASALHVSQPALSQQIRQLEESLG
                     VPLFDRSGRTIHLTDAGEVWRQYASRALQELGAGKRAIHDVADLTRGSLRIAVTPTFT
                     SYFIGPLMADFYARYPGITLQLQEMSQEKIEDLLCRDELDVGIAFAPVHLPELEAIPL
                     LTESLALVVAQHHPLAACEQVALSRLHDEKLVLLSAEFATREQIDHYCEKAGLHPQVV
                     IEANSISAVLELIRRTSLSTLLPAAIATQHDGLKAIPLAPPLLERTAVLLRRKNSWQT
                     AAAKAFLHMALEECADVGENESR"
     misc_feature    complement(414582..415466)
                     /gene="cynR"
                     /locus_tag="ECs_0391"
                     /note="DNA-binding transcriptional regulator CynR;
                     Provisional; Region: PRK11242"
                     /db_xref="CDD:183051"
     gene            415576..416235
                     /gene="cynT"
                     /locus_tag="ECs_0392"
                     /db_xref="GeneID:914494"
     CDS             415576..416235
                     /gene="cynT"
                     /locus_tag="ECs_0392"
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="NP_308419.2"
                     /db_xref="GeneID:914494"
                     /translation="MKEIIDGFLKFQREAFPKREALFKQLATQQSPRTLFISCSDSRL
                     VPELVTQREPGDLFVIRNAGNIVPSYGPEPGGVSASVEYAVAALRVSDIVICGHSNCG
                     AMTAIASCQCMDHMPAVSHWLRYADSARVVNEARPHSDLPSKAAAMVRENVIAQLANL
                     QTHPSVRLALEEGRIALHGWVYDIESGSIAAFDGATRQFVPLAANPRVCAIPLRQPTA
                     A"
     misc_feature    415594..416151
                     /gene="cynT"
                     /locus_tag="ECs_0392"
                     /note="Carbonic anhydrases (CA) are zinc-containing
                     enzymes that catalyze the reversible hydration of carbon
                     dioxide in a two-step mechanism in which the nucleophilic
                     attack of a zinc-bound hydroxide ion on carbon dioxide is
                     followed by the regeneration of an...; Region:
                     beta_CA_cladeB; cd00884"
                     /db_xref="CDD:238449"
     misc_feature    order(415663..415665,415669..415671,415690..415692,
                     415696..415704,415738..415740,415747..415749,
                     415822..415824,415837..415839,415867..415869,
                     415876..415878,416119..416121)
                     /gene="cynT"
                     /locus_tag="ECs_0392"
                     /note="active site clefts [active]"
                     /db_xref="CDD:238449"
     misc_feature    order(415690..415692,415696..415698,415867..415869,
                     415876..415878)
                     /gene="cynT"
                     /locus_tag="ECs_0392"
                     /note="zinc binding site [ion binding]; other site"
                     /db_xref="CDD:238449"
     misc_feature    order(415693..415704,415708..415710,415714..415725,
                     415738..415746,415750..415752,415756..415758,
                     415807..415812,415819..415824,415939..415941,
                     416119..416121,416125..416130,416134..416136,
                     416140..416142)
                     /gene="cynT"
                     /locus_tag="ECs_0392"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238449"
     gene            416266..416736
                     /gene="cynS"
                     /locus_tag="ECs_0393"
                     /db_xref="GeneID:914495"
     CDS             416266..416736
                     /gene="cynS"
                     /locus_tag="ECs_0393"
                     /codon_start=1
                     /transl_table=11
                     /product="cyanate aminohydrolase"
                     /protein_id="NP_308420.1"
                     /db_xref="GeneID:914495"
                     /translation="MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVT
                     AALLGQQALPADAARQVGAKLDLDEDAILLLQMIPLRGCIDDRIPTDPTMYRFYEMLQ
                     VYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF"
     misc_feature    416281..416733
                     /gene="cynS"
                     /locus_tag="ECs_0393"
                     /note="Cyanate lyase [Inorganic ion transport and
                     metabolism]; Region: CynS; COG1513"
                     /db_xref="CDD:224430"
     gene            416742..417923
                     /gene="cynX"
                     /locus_tag="ECs_0394"
                     /db_xref="GeneID:914496"
     CDS             416742..417923
                     /gene="cynX"
                     /locus_tag="ECs_0394"
                     /codon_start=1
                     /transl_table=11
                     /product="cyanate transporter"
                     /protein_id="NP_308421.2"
                     /db_xref="GeneID:914496"
                     /translation="MRNHQKTFTMLLVLVLIGLNMRPLLTSVGPLLPQLRQASGMSFS
                     VAALLTALPVVTMGGLALAGSWLHQHVSERRSVAISLLLIAVGALMRELYPQSALLLS
                     SALLGGVGIGIIQAVMPSVIKRRFQQRTPLVMGLWSAALMGGGGLGAALTPWLVQHSE
                     TWYQTLAWWALPAVVALFAWWWQSTREVASSHKTTTIPVRVVFTPRAWTLGVYFGLIN
                     GGYASLIAWLPAFYIEIGASAQYSGSLLALMTLGQAAGALLMPAMARHQDRRKLLMLA
                     LALQLVGFCGFIWLPLQLPVLWAMVCGLGLGGAFPLCLLLALDHSVQPAIAGKLVAFM
                     QGIGFIIAGLAPWFSGVLRSISGNYLMDWAFHALCVVGLMIITLRFAPARFPQLWVKE
                     A"
     misc_feature    416769..417920
                     /gene="cynX"
                     /locus_tag="ECs_0394"
                     /note="putative cyanate transporter; Provisional; Region:
                     cynX; PRK09705"
                     /db_xref="CDD:236614"
     gene            complement(418026..418637)
                     /gene="lacA"
                     /locus_tag="ECs_0395"
                     /db_xref="GeneID:914497"
     CDS             complement(418026..418637)
                     /gene="lacA"
                     /locus_tag="ECs_0395"
                     /codon_start=1
                     /transl_table=11
                     /product="galactoside O-acetyltransferase"
                     /protein_id="NP_308422.1"
                     /db_xref="GeneID:914497"
                     /translation="MNMSMTERIKAGKLFTDMCEGLPEKRLRRKTLMYEFNHSHPSEV
                     DKRESLIKEMFATVGENAWVEPPVYFSYGSNIHIGRNFYANFNLTIVDDYTVTIGDNV
                     LIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNNVWIGSHVVINPGVTIGDNSVIGA
                     GSIVTKDIPPNVVAAGVPCRVIREINDRDKQYYFRDYKVESSV"
     misc_feature    complement(418029..418637)
                     /gene="lacA"
                     /locus_tag="ECs_0395"
                     /note="galactoside O-acetyltransferase; Reviewed; Region:
                     lacA; PRK09527"
                     /db_xref="CDD:181930"
     misc_feature    complement(order(418098..418100,418104..418115,
                     418140..418145,418149..418151,418158..418163,
                     418197..418199,418212..418217,418221..418223,
                     418257..418259,418263..418268,418287..418289,
                     418293..418295,418299..418301,418305..418307,
                     418323..418325,418329..418331,418359..418361,
                     418365..418367,418383..418385,418389..418391,
                     418425..418427,418560..418562,418587..418589))
                     /gene="lacA"
                     /locus_tag="ECs_0395"
                     /note="active site"
                     /db_xref="CDD:100047"
     misc_feature    complement(order(418257..418259,418263..418268,
                     418293..418295,418299..418301,418329..418331,
                     418359..418361,418365..418367,418383..418385,
                     418389..418391,418425..418427,418560..418562,
                     418587..418589))
                     /gene="lacA"
                     /locus_tag="ECs_0395"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100047"
     misc_feature    complement(order(418107..418109,418143..418145,
                     418155..418160,418167..418169,418173..418175,
                     418197..418199,418206..418214,418221..418223,
                     418227..418229,418248..418250,418254..418256,
                     418272..418277,418281..418289,418293..418295,
                     418305..418307,418311..418313,418317..418319,
                     418329..418331,418335..418337,418377..418382,
                     418428..418433,418437..418439,418515..418517,
                     418536..418538,418548..418550,418557..418559))
                     /gene="lacA"
                     /locus_tag="ECs_0395"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:100047"
     misc_feature    complement(order(418104..418106,418110..418115,
                     418140..418145,418158..418163,418197..418199,
                     418212..418217,418221..418223,418287..418289,
                     418293..418295,418299..418301,418305..418307))
                     /gene="lacA"
                     /locus_tag="ECs_0395"
                     /note="CoA binding site [chemical binding]; other site"
                     /db_xref="CDD:100047"
     gene            complement(418703..419956)
                     /gene="lacY"
                     /locus_tag="ECs_0396"
                     /db_xref="GeneID:914498"
     CDS             complement(418703..419956)
                     /gene="lacY"
                     /locus_tag="ECs_0396"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose permease"
                     /protein_id="NP_308423.1"
                     /db_xref="GeneID:914498"
                     /translation="MYYLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSD
                     TGIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYN
                     ILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALCASIVGI
                     MFTINNQFVFWLGSGCALILAILLFFAKTDAPSSATVANAVGANHSAFSLKLALELFR
                     QPKLWFLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFGYVTTMGELLNASIM
                     FFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKTLHMFEVPFLLVGCF
                     KYITSQFEVRFSATIYLVCFCFFKQLAMIFMSVLAGNMYESIGFQGAYLVLGLVALGF
                     TLISVFTLSGPGPLSLLRRQVNEVA"
     misc_feature    complement(418718..419956)
                     /gene="lacY"
                     /locus_tag="ECs_0396"
                     /note="LacY proton/sugar symporter; Region: LacY_symp;
                     pfam01306"
                     /db_xref="CDD:396050"
     gene            complement(420008..423082)
                     /gene="lacZ"
                     /locus_tag="ECs_0397"
                     /db_xref="GeneID:914499"
     CDS             complement(420008..423082)
                     /gene="lacZ"
                     /locus_tag="ECs_0397"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-D-galactosidase"
                     /protein_id="NP_308424.1"
                     /db_xref="GeneID:914499"
                     /translation="MTMITDSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEAR
                     TNRPSQQLRSLNGEWQFVWFPAPEAVPESWLECDLPDADTVVVPSNWQMHGYDAPIYT
                     NVTYPITVNPPFVPTENPTGCYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWV
                     GYGQDSRLLSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHK
                     PTTQISDFHVATLFNDDFSRAVLEAEVQMYGELRDELRVTVSLWQGETQVASGTAPFG
                     GEIIDERGGYADRVTLGLNVENPKLWSAEIPNIYRAVVELHTADGTLIEAEACDVGFR
                     EVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSH
                     YPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRN
                     HPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTSATDIICPMYARVD
                     EDQPFPAVPKWSIKKWLSLPGEMRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGG
                     FVWDLVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQ
                     QQFFQFRLSGRTIEVTSEYLFRHSDNELLHWTVALDGKPLASGEVPLDVAPQGKQVIE
                     LPELPRLESTGQLWLTVHVVQPNATAWSEAGHISAWQQWRLAENLSVTLPSAPHAIPQ
                     LTTSETDFCIELDNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSE
                     ATRIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTVHAWQHQGKTLFISRKT
                     YRIDGSGQMAITVDVEVASDTPHPARIGLTCQLAQVAERVNWLGLGPQENYPDRLTAA
                     CFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETS
                     HRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK"
     misc_feature    complement(420011..423082)
                     /gene="lacZ"
                     /locus_tag="ECs_0397"
                     /note="beta-galactosidase; Region: lacZ; PRK09525"
                     /db_xref="CDD:236548"
     gene            complement(423205..424296)
                     /gene="lacI"
                     /locus_tag="ECs_0398"
                     /db_xref="GeneID:914500"
     CDS             complement(423205..424296)
                     /gene="lacI"
                     /locus_tag="ECs_0398"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose operon repressor"
                     /protein_id="NP_308425.4"
                     /db_xref="GeneID:914500"
                     /translation="MVNVKPVTLYDVAEYAGVSYQTVSRVVNQASHVSAKTREKVEAA
                     MAELNYIPNRVAQQLAGKQSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMV
                     ERSGVEACKAAVHNLLAQRVSGLIINYPLDDQDAIAVEAACANVPALFLDVSDQTPIN
                     SIIFSHEDGTRLGVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRNQIQPIAE
                     REGDWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGY
                     DDTEDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLLPVSLVKRKTTLA
                     PKTQTASPRALADSLMQLARQVSRLESGQ"
     misc_feature    complement(423268..424290)
                     /gene="lacI"
                     /locus_tag="ECs_0398"
                     /note="lac repressor; Reviewed; Region: lacI; PRK09526"
                     /db_xref="CDD:181929"
     gene            complement(424324..425277)
                     /locus_tag="ECs_0399"
                     /db_xref="GeneID:914501"
     CDS             complement(424324..425277)
                     /locus_tag="ECs_0399"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_308426.1"
                     /db_xref="GeneID:914501"
                     /translation="MRPLTVAIIAVAGFSPFHLSVPFIVFSEKMAEKKRFHVIICAEK
                     PGNVDSADGFSVTATHDYTAVIQADIVIIPYWGTITQKPPQKLLEALTTARDNGAQIV
                     GLCLGTFVLGYAGLLKNKRAATHWEFEREFQARFPQTHLDINALYVDDDGIITSAGTA
                     AALDCCLYIVRQHFGSDYANHIARRMVVPPYRTGGQAQFIEQPVPKNTHDERINLLLD
                     YLRQNIAQQHDLDSLAQRVMMSRRTLTRHFMKATGSSIAEWLITERLRRSQELLGSSQ
                     LPVERIAAEVGFLSPVTWRQHFKSHFGVSPAEWRKTFRGMA"
     misc_feature    complement(424327..425274)
                     /locus_tag="ECs_0399"
                     /note="Transcriptional regulator GlxA family, contains an
                     amidase domain and an AraC-type DNA-binding HTH domain
                     [Transcription]; Region: GlxA; COG4977"
                     /db_xref="CDD:227311"
     gene            complement(425297..426073)
                     /locus_tag="ECs_0400"
                     /db_xref="GeneID:914502"
     CDS             complement(425297..426073)
                     /locus_tag="ECs_0400"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308427.2"
                     /db_xref="GeneID:914502"
                     /translation="MKITQIRNATQIIQYAGKTFLIDPLLAPKGSYPGFAGTARAEIR
                     NPTVELPCDLTTLLNVDALIVTHLHEDHWDETASRVVPKDKLIYVQNEQDAESLNKQG
                     FTHLTVLTDETKFGDITLHKTTGQHGSDRTYADPAMAKRLGAACGVVFQHPTEKTLYL
                     AGDTLWRDDVEATMLTFQPEVVVLNAGFAHVLGHGAIIMGAEDILKTHFTLPEAQIIA
                     THMEAVNHCLLTRDALKEYARDNQIIEFVNVPEDGETLTF"
     misc_feature    complement(425318..426073)
                     /locus_tag="ECs_0400"
                     /note="L-ascorbate metabolism protein UlaG, beta-lactamase
                     superfamily [Carbohydrate transport and metabolism];
                     Region: UlaG; COG2220"
                     /db_xref="CDD:225130"
     gene            complement(426188..427135)
                     /gene="mhpR"
                     /locus_tag="ECs_0401"
                     /db_xref="GeneID:914503"
     CDS             complement(426188..427135)
                     /gene="mhpR"
                     /locus_tag="ECs_0401"
                     /codon_start=1
                     /transl_table=11
                     /product="mhp operon transcriptional activator"
                     /protein_id="NP_308428.3"
                     /db_xref="GeneID:914503"
                     /translation="MIFYCALSIERVFSATIKTCPNVHQVHNVVLTIEMSINMQNNEQ
                     TEYKTVRGLTRGLMLLNMLNKLDGGASVGLLAELSGLHRTTVRRLLETLQEEGYVRRS
                     PSDDSFRLTIKVRQLSEGFRDEQWISALAAPLLGDLLREVVWPTDVSTLDVDAMVVRE
                     TTHRFSRLSFHRAMVGRRLPLLKTASGLTWLAFCPEQERKELIEMLASRPGDDYQLAR
                     EPLKLEAILARARKEGYGQNYRGWDQEEKIASIAVPLRSEQRVIGCLNLVYMASAMTI
                     EQAAEKHLPALQRVAKQIEEGVESQAILVAGRRSGVHLR"
     misc_feature    complement(426218..427003)
                     /gene="mhpR"
                     /locus_tag="ECs_0401"
                     /note="DNA-binding transcriptional regulator; Region:
                     PRK09834"
                     /db_xref="CDD:182100"
     gene            427212..428876
                     /gene="mhpA"
                     /locus_tag="ECs_0402"
                     /db_xref="GeneID:914504"
     CDS             427212..428876
                     /gene="mhpA"
                     /locus_tag="ECs_0402"
                     /codon_start=1
                     /transl_table=11
                     /product="3-(3-hydroxyphenyl)propionate hydroxylase"
                     /protein_id="NP_308429.1"
                     /db_xref="GeneID:914504"
                     /translation="MAIQHPDIQPAVNHSVQVAIAGAGPVGLMMANYLGQMGIDVLVV
                     EKLDKLIDYPRAIGIDDEALRTMQSVGLVDNVLPHTTPWHAMRFLTPKGRCFADIQPM
                     TDEFGWPRRNAFIQPQVDAVMLEGVSRFPNVRCLFSRELEAFSQQDDEVTLHLKTAEG
                     LREIVKAQWLVACDGGASFVRRTLNVPFEGKTAPNQWIVVDIANDPLSTPHIYLCCDP
                     VRPYVSAALPHAVRRFEFMVMPGETEEQLREPQNMRKLLSKVLPNPDNVELIRQRVYT
                     HNARLAQRFRIDRVLLAGDAAHIMPVWQGQGYNSGMRDAFNLAWKLALVIQGKARDAL
                     LDTYQQERRDHAKAMIDLSVTAGNVLAPPKRWQGTLRDGVSWLLNYLPPVKRYFLEMR
                     FKPMPQYYGGALVREGEAKHSPVGKMFIQPKVTLENGDVTLLDNAIGANFAVIGWGCN
                     PLWGMSDEQIQQWRALSTRFIQVVPEVQIHTAQDNHDGVLRVGDTQGRLRSWFAQHNA
                     SLVVMRPDRFVAATAIPQTLGKTLNKLASVMTLTRPDADVSVEKVA"
     misc_feature    427212..428843
                     /gene="mhpA"
                     /locus_tag="ECs_0402"
                     /note="bifunctional
                     3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid
                     hydroxylase; Region: mhpA; PRK06183"
                     /db_xref="CDD:235727"
     gene            428878..429822
                     /gene="mhpB"
                     /locus_tag="ECs_0403"
                     /db_xref="GeneID:914505"
     CDS             428878..429822
                     /gene="mhpB"
                     /locus_tag="ECs_0403"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-dihydroxyphenylpropionate 1,2-dioxygenase"
                     /protein_id="NP_308430.1"
                     /db_xref="GeneID:914505"
                     /translation="MHAYLHCLSHSPLVGYVDPAQEVLDEVNGVIASARERIAAFSPE
                     LVVLFAPDHYNGFFYDVMPPFCLGVGATAIGDFGSAAGELPVPVELAEACAHAVMKSG
                     IDLAVSYCMQVDHGFAQPLEFLLGGLDKVPVLPVFINGVATPLPGFQRTRMLGEAIGR
                     FTSTLNKRVLFLGSGGLSHQPPVPELAKADAHMRDRLLGSGKDLPASERELRQQRVIS
                     AAEKFVEDQRTLHPLNPIWDNQFMTLLEQGRIQELDAVSNEELSAIAGKSTHEIKTWV
                     AAFAAISAFGNWRSEGRYYRPIPEWIAGFGSLSARTEN"
     misc_feature    428878..429810
                     /gene="mhpB"
                     /locus_tag="ECs_0403"
                     /note="Subunit B of the Class III Extradiol ring-cleavage
                     dioxygenase, 2,3-dihydroxyphenylpropionate 1,2-dioxygenase
                     (MhpB), which catalyzes the oxidization and subsequent
                     ring-opening of 2,3-dihydroxyphenylpropionate; Region:
                     MhpB_like; cd07365"
                     /db_xref="CDD:153377"
     misc_feature    order(428905..428913,429034..429036,429220..429222,
                     429412..429414,429688..429690,429781..429786)
                     /gene="mhpB"
                     /locus_tag="ECs_0403"
                     /note="putative active site [active]"
                     /db_xref="CDD:153377"
     misc_feature    order(428905..428907,429034..429036,429688..429690)
                     /gene="mhpB"
                     /locus_tag="ECs_0403"
                     /note="Fe(II) binding site [ion binding]; other site"
                     /db_xref="CDD:153377"
     misc_feature    order(428911..428913,429034..429042,429049..429054,
                     429106..429111,429298..429312,429571..429579,
                     429649..429654,429661..429669,429676..429681,
                     429688..429690,429766..429771,429781..429783)
                     /gene="mhpB"
                     /locus_tag="ECs_0403"
                     /note="putative dimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:153377"
     misc_feature    order(429052..429054,429058..429072,429139..429144,
                     429151..429156,429163..429168,429172..429177,
                     429181..429183,429187..429207,429307..429309,
                     429316..429318,429322..429327,429367..429369)
                     /gene="mhpB"
                     /locus_tag="ECs_0403"
                     /note="putative tetramer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:153377"
     gene            429840..430706
                     /gene="mhpC"
                     /locus_tag="ECs_0404"
                     /db_xref="GeneID:914506"
     CDS             429840..430706
                     /gene="mhpC"
                     /locus_tag="ECs_0404"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-6-ketonona-2,4-dienedioic acid
                     hydrolase"
                     /protein_id="NP_308431.3"
                     /db_xref="GeneID:914506"
                     /translation="MSYQPQTEAATSRFLNVEEAGKTLRIHFNDCGQGDETVVLLHGS
                     GPGATGWANFSRNIDPLVEAGYRVILLDCPGWGKSDSIVNSGSRSDLNARILKSVVDQ
                     LDIAKIHLLGNSMGGHSSVAFTLNWPERVGKLVLMGGGTGGMSLFTPMPTEGIKRLNQ
                     LYRQPTIENLKLMMDIFVFDTSDLTDALFEARLNNMLSRRDHLENFVKSLEANPKQFP
                     DFGPRLAEIKAQTLIVWGRNDRFVPMDAGLRLLSGIAGSELHIFRDCGHWAQWEHADA
                     FNQLVLNFLARA"
     misc_feature    429858..430697
                     /gene="mhpC"
                     /locus_tag="ECs_0404"
                     /note="2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate
                     hydrolase; Region: biphenyl_bphD; TIGR03343"
                     /db_xref="CDD:132386"
     gene            430716..431525
                     /gene="mhpD"
                     /locus_tag="ECs_0405"
                     /db_xref="GeneID:914507"
     CDS             430716..431525
                     /gene="mhpD"
                     /locus_tag="ECs_0405"
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-4-pentenoate hydratase"
                     /protein_id="NP_308432.2"
                     /db_xref="GeneID:914507"
                     /translation="MTKHTLEQLAADLRRAAEQGEAIAPLRDLIGIDNAEAAYAIQHI
                     NVQYDVAQGRRVVGRKVGLTHPKVQQQLGVDQPDFGTLFADMCYGDNEIIPFSRVLQP
                     RIEAEIALVLNRDLPATDITFDELYNAIEWVLPALEVVGSRIRDWSIQFVDTVADNAS
                     CGVYVIGGPAQRPAGLDLKNCAMKMTRNNEEVSSGRGSECLGHPLNAAVWLARKMASL
                     GEPLRAGDIILTGALGPMVAVNAGDRFEAHIEGIGSVAAAFSSAAPKGSLS"
     misc_feature    430716..431501
                     /gene="mhpD"
                     /locus_tag="ECs_0405"
                     /note="2-keto-4-pentenoate hydratase; Provisional; Region:
                     mhpD; PRK11342"
                     /db_xref="CDD:183092"
     gene            431522..432472
                     /gene="mhpF"
                     /locus_tag="ECs_0406"
                     /db_xref="GeneID:914508"
     CDS             431522..432472
                     /gene="mhpF"
                     /locus_tag="ECs_0406"
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde-CoA dehydrogenase II"
                     /protein_id="NP_308433.1"
                     /db_xref="GeneID:914508"
                     /translation="MSKRKVAIIGSGNIGTDLMIKILRHDQHLEMAVMVGIDPQSDGL
                     ARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSAGAHVKNDAALREAKPDIRLIDL
                     TPAAIGPYCVPVVNLEENVDQLNVNMVTCGGQATIPMVAAVSRVVRVHYAEIIASIAS
                     KSAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEAS
                     QDDIEASINEMAEAVQAYVPGYRLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEV
                     EGAAHYLPAYAGNLDIMTSSALATAEKMAQSLARKAGEAA"
     misc_feature    431522..432469
                     /gene="mhpF"
                     /locus_tag="ECs_0406"
                     /note="acetaldehyde dehydrogenase; Validated; Region:
                     PRK08300"
                     /db_xref="CDD:236227"
     gene            432469..433482
                     /gene="mhpE"
                     /locus_tag="ECs_0407"
                     /db_xref="GeneID:914509"
     CDS             432469..433482
                     /gene="mhpE"
                     /locus_tag="ECs_0407"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic
                     acid aldolase"
                     /protein_id="NP_308434.1"
                     /db_xref="GeneID:914509"
                     /translation="MNGKKLYISDVTLRDGMHAIRHQYSLENVRQIAKALDDARVDSI
                     EVAHGDGLQGSSFNYGFGAHSDLEWIEAAADVVKHAKIATLLLPGIGTIHDLKNAWQA
                     GARVVRVATHCTEADVSAQHIQYARELGMDTVGFLMMSHMTTPENLAKQAKLMEGYGA
                     TCIYVVDSGGAMNMSDIRDRFRALKAVLKPETQTGMHAHHNLSLGVANSIAAVEEGCD
                     RIDASLAGMGAGAGNAPLEVFIAAVDKLGWQHGADLYALMDAADDLVRPLQDRPVRVD
                     RETLALGYAGVYSSFLRHCETAAARYGLSAVDILVELGKRRMVGGQEDMIVDVALDLR
                     NNK"
     misc_feature    432475..433467
                     /gene="mhpE"
                     /locus_tag="ECs_0407"
                     /note="4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic
                     acid aldolase,; Validated; Region: PRK08195"
                     /db_xref="CDD:181282"
     gene            433658..434869
                     /gene="mhpT"
                     /locus_tag="ECs_0408"
                     /db_xref="GeneID:914510"
     CDS             433658..434869
                     /gene="mhpT"
                     /locus_tag="ECs_0408"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyphenylpropionic transporter"
                     /protein_id="NP_308435.2"
                     /db_xref="GeneID:914510"
                     /translation="MSTRTPSSSSSRLMLTIGLCFLVALMEGLDLQAAGIAAGGIAQA
                     FALDKMQMGWIFSAGILGLLPGALVGGMLADRYGRKRILIGSVALFGLFSLATAIAWD
                     FPSLVFARLMTGVGLGAALPNLIALTSEAAGPRFRGTAVSLMYCGVPIGAALAATLGF
                     AGANLAWQTVFWVGGVVPLILVPLLMRWLPESAVFAGEKQAAPPLRALFAPETATATL
                     LLWLCYFFTLLVVYMLINWLPLLLVEQGFQPSQAAGVMFALQMGAASGTLMLGALMDK
                     LRPVTMSLLIYSGMLASLLALGTVSSFNGMLLAGFVAGLFATGGQSVLYALAPLFYSS
                     QIRATGVGTAVAVGRLGAMSGPLLAGKMLALGTGTVGVMAASAPGILVAGLAVFILMS
                     RRLRMQPCADA"
     misc_feature    433694..434860
                     /gene="mhpT"
                     /locus_tag="ECs_0408"
                     /note="putative 3-hydroxyphenylpropionic transporter MhpT;
                     Provisional; Region: PRK11551"
                     /db_xref="CDD:236927"
     gene            434971..435510
                     /gene="yaiL"
                     /locus_tag="ECs_0409"
                     /db_xref="GeneID:914511"
     CDS             434971..435510
                     /gene="yaiL"
                     /locus_tag="ECs_0409"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308436.2"
                     /db_xref="GeneID:914511"
                     /translation="MAKLTLQEQLLKAGLVTSKKAAKVERTAKKSRVQAREARAAVEE
                     NKKAQLERDKQLSEQQKQAALAKEYKAQVKQLIEMNRITIANGDIGFNFTDGNLIKKI
                     FVDKLTQAQLINGRLAIARLLVDNNSEGEYAIIPASVADKIAQRDASSIVLHSALSAE
                     EQDEDNPYADFKVPDDLMW"
     misc_feature    434971..435507
                     /gene="yaiL"
                     /locus_tag="ECs_0409"
                     /note="Uncharacterized conserved protein YaiL, DUF2058
                     family [Function unknown]; Region: YaiL; COG3122"
                     /db_xref="CDD:225664"
     gene            complement(435635..436468)
                     /gene="frmB"
                     /locus_tag="ECs_0410"
                     /db_xref="GeneID:914512"
     CDS             complement(435635..436468)
                     /gene="frmB"
                     /locus_tag="ECs_0410"
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="NP_308437.1"
                     /db_xref="GeneID:914512"
                     /translation="MELIEKHASFGGWQNVYRHYSASLKCEMNVGVYLPPKAAGEKLP
                     VLYWLSGLTCNEQNFITKSGVQRYAAEHNIIVVAPDTSPRGSHVADADRYDLGQGAGF
                     YLNATQAPWNEHYKMYDYIRNELPDLVMNHFPATAKKSISGHSMGGLGALVLALRNPD
                     EYVSVSAFSPIVSPSQVPWGQQAFAAYLGENKEAWLDYHPVSLISQGQRVAEIMVDQG
                     LSDDFYAEQLRTQNLEKICQEMNIKTLIRYHEGYDHSYYFVSSFIGEHIAYHANKLNM
                     R"
     misc_feature    complement(435647..436465)
                     /gene="frmB"
                     /locus_tag="ECs_0410"
                     /note="alpha/beta hydrolases; Region: Abhydrolase;
                     cl21494"
                     /db_xref="CDD:451272"
     misc_feature    complement(436028..436042)
                     /gene="frmB"
                     /locus_tag="ECs_0410"
                     /note="nucleophilic elbow [active]"
                     /db_xref="CDD:238382"
     gene            complement(436561..437670)
                     /gene="frmA"
                     /locus_tag="ECs_0411"
                     /db_xref="GeneID:914513"
     CDS             complement(436561..437670)
                     /gene="frmA"
                     /locus_tag="ECs_0411"
                     /codon_start=1
                     /transl_table=11
                     /product="S-(hydroxymethyl)glutathione dehydrogenase"
                     /protein_id="NP_308438.1"
                     /db_xref="GeneID:914513"
                     /translation="MKSRAAVAFAPGKPLEIVEIDVAPPKKGEVLIKVTHTGVCHTDA
                     FTLSGDDPEGVFPVVLGHEGAGVVVEVGEGVTSVKPGDHVIPLYTAECGECEFCRSGK
                     TNLCVAVRETQGKGLMPDGTTRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEAN
                     HEHVCLLGCGVTTGIGAVHNTAKVQPGDSVAVFGLGAIGLAVVQGARQAKAGRIIAID
                     TNPKKFDLARRFGATDCINPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALES
                     AHRGWGQSVIIGVAGSGQEISTRPFQLVTGRVWKGSAFGGVKGRSQLPGMVEDAMKGD
                     IDLEPFVTHTMSLDEINDAFDLMHEGKSIRTVIRY"
     misc_feature    complement(436567..437670)
                     /gene="frmA"
                     /locus_tag="ECs_0411"
                     /note="class III alcohol dehydrogenases; Region:
                     alcohol_DH_class_III; cd08300"
                     /db_xref="CDD:176260"
     misc_feature    complement(order(436732..436734,436804..436806,
                     437164..437166,437404..437409,437485..437487,
                     437512..437520,437545..437547,437551..437553))
                     /gene="frmA"
                     /locus_tag="ECs_0411"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:176260"
     misc_feature    complement(order(437164..437166,437482..437487,
                     437551..437553))
                     /gene="frmA"
                     /locus_tag="ECs_0411"
                     /note="catalytic Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176260"
     misc_feature    complement(order(436579..436581,436729..436737,
                     436807..436812,436864..436869,436879..436884,
                     437002..437004,437014..437019,437077..437091,
                     437152..437154,437164..437166,437545..437550))
                     /gene="frmA"
                     /locus_tag="ECs_0411"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:176260"
     misc_feature    complement(order(437353..437355,437377..437379,
                     437386..437388,437395..437397))
                     /gene="frmA"
                     /locus_tag="ECs_0411"
                     /note="structural Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176260"
     misc_feature    complement(order(436732..436749,436756..436764,
                     436771..436794,436801..436803,436828..436839,
                     436858..436863,436894..436896,436909..436911,
                     437350..437352,437356..437358,437362..437367,
                     437371..437373,437380..437385))
                     /gene="frmA"
                     /locus_tag="ECs_0411"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:176260"
     gene            complement(437705..437980)
                     /gene="frmR"
                     /locus_tag="ECs_0412"
                     /db_xref="GeneID:914514"
     CDS             complement(437705..437980)
                     /gene="frmR"
                     /locus_tag="ECs_0412"
                     /codon_start=1
                     /transl_table=11
                     /product="regulator protein that represses frmRAB operon"
                     /protein_id="NP_308439.4"
                     /db_xref="GeneID:914514"
                     /translation="MPSTPEEKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAA
                     VRGAANGLMAEVLESHIRETFDRNDCYSREVSQSVDDTIELVRAYLK"
     misc_feature    complement(437708..437980)
                     /gene="frmR"
                     /locus_tag="ECs_0412"
                     /note="formaldehyde-responsive transcriptional repressor
                     FrmR; Region: PRK11352"
                     /db_xref="CDD:183095"
     misc_feature    complement(order(437789..437791,437801..437803,
                     437876..437878,437972..437974))
                     /gene="frmR"
                     /locus_tag="ECs_0412"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:197388"
     misc_feature    complement(order(437720..437749,437753..437758,
                     437786..437788,437795..437803,437807..437815,
                     437819..437824,437831..437836,437843..437848,
                     437852..437857,437861..437869,437873..437881,
                     437885..437896,437903..437908,437912..437917,
                     437924..437926,437933..437938,437945..437950,
                     437957..437959))
                     /gene="frmR"
                     /locus_tag="ECs_0412"
                     /note="putative homotetramer interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:197388"
     misc_feature    complement(order(437720..437731,437738..437740,
                     437801..437803,437813..437815,437822..437824,
                     437831..437836,437843..437848,437852..437857,
                     437861..437869,437873..437881,437885..437896,
                     437903..437908,437912..437917,437924..437926,
                     437933..437938,437945..437950,437957..437959))
                     /gene="frmR"
                     /locus_tag="ECs_0412"
                     /note="putative homodimer interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:197388"
     misc_feature    complement(order(437732..437737,437741..437749,
                     437753..437758,437786..437791,437795..437800,
                     437807..437812,437819..437821))
                     /gene="frmR"
                     /locus_tag="ECs_0412"
                     /note="putative homodimer-homodimer interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:197388"
     misc_feature    complement(order(437738..437740,437801..437803))
                     /gene="frmR"
                     /locus_tag="ECs_0412"
                     /note="putative allosteric switch controlling residues;
                     other site"
                     /db_xref="CDD:197388"
     gene            complement(438140..439186)
                     /gene="afuC"
                     /locus_tag="ECs_0413"
                     /db_xref="GeneID:914515"
     CDS             complement(438140..439186)
                     /gene="afuC"
                     /locus_tag="ECs_0413"
                     /codon_start=1
                     /transl_table=11
                     /product="ferric transporter subunit"
                     /protein_id="NP_308440.2"
                     /db_xref="GeneID:914515"
                     /translation="MSQKNFVELRNVTKRFGSNTVIDNINLTIPQGQMVTLLGPSGCG
                     KTTILRLVAGLEKPSEGQIFIDGEDVTHRSIQQRDICMVFQSYALFPHMSLGENVGYG
                     LKMLGVSRSEVKQRVKEALAMVDLEGFEDRYVDQISGGQQQRVALARALILKPKVLLF
                     DEPLSNLDANLRRSMRDKIRELQKQFNITSLYVTHDQSEAFAVSDTVLVMNKGHIMQI
                     GSPQDLYRQPASRFMASFMGDANLFPANFSEEYVDIYGYRLPRAAHFPVQGSGTVGVR
                     PEAITLSNHGEESQRCVIRHVAYMGPQYEVTVEWHGQEILLQVNATRLQPDIGEHYYL
                     EIHPYGMFVLADAA"
     misc_feature    complement(438143..439186)
                     /gene="afuC"
                     /locus_tag="ECs_0413"
                     /note="ferric ABC transporter ATP-binding protein; Region:
                     fbpC; PRK11432"
                     /db_xref="CDD:183133"
     gene            complement(439198..441276)
                     /locus_tag="ECs_0414"
                     /db_xref="GeneID:914516"
     CDS             complement(439198..441276)
                     /locus_tag="ECs_0414"
                     /codon_start=1
                     /transl_table=11
                     /product="ferric transport system permease"
                     /protein_id="NP_308441.1"
                     /db_xref="GeneID:914516"
                     /translation="MSQTLALHPVKKRDAIFLWVLLGWLAFVLLPSWSLDYGLLESTS
                     DEILGAYGWSHFNISWLWYLLPSLLLVRPFRQATREQRSRHYFDAGWALLCMAFIVIS
                     ATVAGRGLGYAAIVLFVELGAIMTLALTRLEWLGGDRFVIGSLIAIVALIGIFIVWPS
                     IAIFIPMFTNDAGELAPLAFMTVLSQAHIVQVIVNSIVLSIAVGIGCAFFGLVLAIYT
                     TRIAKRSAIIGRIFSILPIVTPPFVVGLGVTLMMGRSGYVTEFMVEWFGLTNTNWLYG
                     FTGIWLAQVLAFTPMAFMILDGAIKTIHPSLEEASYTLRASRWQTFNGVFVPLLKPAL
                     ANAFLIVVVQSLADFSNPLVLGGNFDVLATQIYFYITGSQLDYQAASTLGAFLLLFSL
                     LVFCIQYMWIGKRSYVTVSGKSYRGDVQPLPVTLVWSVVAILAIWIAFNALLYGSIFY
                     GSFTVNWGVDYTLTLDNFIKLFGQGMSDGAWPSLLDTLLYAGIAAPITAIFGLLIAWV
                     VVRQQFKGKKTIEFTTMLCFAVPGTVAGVSYILAFNSAPVYLTGTAAIVIISMVMRNV
                     PVGIRAGIAGLGQIDKSLDEASLSLRAGSLRTITHILLPLLRPAILSALIYSFVRAIT
                     TVSAIVFLVTPDTRVATAYILNRVEDGEYGVAIAYGSILIVVMLAIIFLFDWLIGEAR
                     ISRSKAKNQA"
     misc_feature    complement(439240..440871)
                     /locus_tag="ECs_0414"
                     /note="ABC-type Fe3+ transport system, permease component
                     [Inorganic ion transport and metabolism]; Region: FbpB;
                     COG1178"
                     /db_xref="CDD:224099"
     gene            complement(441345..442376)
                     /locus_tag="ECs_0415"
                     /db_xref="GeneID:914517"
     CDS             complement(441345..442376)
                     /locus_tag="ECs_0415"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic-iron-binding protein"
                     /protein_id="NP_308442.1"
                     /db_xref="GeneID:914517"
                     /translation="MKMTFTSTLIASAVALATLTGAAQAKGRLVVYCSATNEMCEAET
                     KAFGEKYDVKTSFIRNGSGSTLAKVDAEKKNPQADVWYGGTLDPQSQAGEMGLLQAYK
                     SPNLEQIMEKFRDPAKVKGNLSSAVYVGILGFGVNTDRLKEKNLPVPKCWKDLTKPEY
                     KGEIQIADPQSSGTAYTALATFAQLWGEDQAFDYLKQLNANVSQYTKSGIAPARNAAR
                     GETAIGIGFLHDYSLEKEQGAPLELISPCEGTGYEIGGVSILKGARNLDNAKLFVDWV
                     LSKEAQELAWKKGKSYQILTNTTAETSPNSLKLDDLKLINYDMDKYGSTDVRKALINK
                     WVSEVKMGK"
     misc_feature    complement(441405..442295)
                     /locus_tag="ECs_0415"
                     /note="Substrate binding domain of a putative ferric iron
                     transporter, a member of the type 2 periplasmic binding
                     fold superfamily; Region: PBP2_Fbp_like_1; cd13544"
                     /db_xref="CDD:270262"
     misc_feature    complement(order(441687..441692,441696..441698,
                     441747..441755,441855..441860))
                     /locus_tag="ECs_0415"
                     /note="putative chemical substrate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:270262"
     gene            complement(442373..443677)
                     /locus_tag="ECs_0416"
                     /db_xref="GeneID:914518"
     CDS             complement(442373..443677)
                     /locus_tag="ECs_0416"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein"
                     /protein_id="NP_308443.1"
                     /db_xref="GeneID:914518"
                     /translation="MHARSAREINQCYRTLRPRLLMCMIIGYAAFYLTRKSVNYVLPA
                     LQTDLGLDKGDIGLLGSLFYLSYGLSKFTAGLWHDSHGQRGFMGVGLFATGLLNVVFA
                     FGESLTLLLVVWTLNGFFQGWGWPPCARLLTHWYSRNERGFWWGCWNMSINIGGAIIP
                     LISAFAAHWWGWQAAMLTPGIISMALGIWLTLQLKGTPQEEGLPTVGHWRHDPLELRQ
                     EQQSPPMGLWQMLRTTMLQNPLIWLLGVSYVLVYVIRIALNDWGNIWLTESHGVNLLS
                     ANATVMLFEVGGLLGALFAGWGSDLLFSGQRAPMILLFTLGLMVSVAALWLAPVHHYA
                     LLAVCFFTVGFFVFGPQMLIGLAAVECGHKAAAGSITGFLGLFAYLGAALAGWPLSLV
                     IERYGWPGMFSLLSVAAVLMGLLLMPLLMAGITTTHARRIKQ"
     misc_feature    complement(442451..443668)
                     /locus_tag="ECs_0416"
                     /note="glucose-6-phosphate receptor/MFS transporter UhpC;
                     Region: PRK11663"
                     /db_xref="CDD:183266"
     gene            complement(443762..445303)
                     /locus_tag="ECs_0417"
                     /db_xref="GeneID:914519"
     CDS             complement(443762..445303)
                     /locus_tag="ECs_0417"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine protein kinase"
                     /protein_id="NP_308444.1"
                     /db_xref="GeneID:914519"
                     /translation="MSRNLRHWVILLFIVLAWGTGWLMLWTLSFYLTNNGQQAVLFLP
                     QGVYLALVILLSRRYWPALVLPPLLMMFWLHSEQLLNGYLMLATPVISLFPALLAQNF
                     WHRFPLYWQRLTLLLATVTAASLLNTALLSPFMSGPIMLPGLTSFTGGVLLTPFVYLI
                     FEFLRQQHRYQLLGLDTHNPPLRTSLIIWCSLFFIIGIGTQMVLSPEIERLLLIVVFL
                     PNVVMAWKFGWQGGVLSGLLGSMMITIARQIGVGFSNLVELEIFLATQALLGIGLGIA
                     ISRQQHLALNLHHYRQRLEAELAARRALAEKLIHTEEDTRKNLARELHDEIGQNITAI
                     QIQSQLVKRARDPAQIQSAASQINELARRIHLSTRQLLRQLRPPALDELTFREALLHL
                     INEFAFSERGIHCQFAYQLNSTPENETVRFTLYRLLQELLNNICKHAEASEVTIILRQ
                     QGEVLHLEVSDNGVGIASGKMAGFGIQGMRERVSALGGDLTLEKQHGTRVIVNLPTFL
                     QQIAG"
     misc_feature    complement(443780..445291)
                     /locus_tag="ECs_0417"
                     /note="Signal transduction histidine kinase,
                     glucose-6-phosphate specific [Signal transduction
                     mechanisms]; Region: UhpB; COG3851"
                     /db_xref="CDD:226369"
     gene            complement(445303..445932)
                     /locus_tag="ECs_0418"
                     /db_xref="GeneID:914520"
     CDS             complement(445303..445932)
                     /locus_tag="ECs_0418"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription regulator"
                     /protein_id="NP_308445.1"
                     /db_xref="GeneID:914520"
                     /translation="MIRVVLVDDHVVVRSGFAQLLSLEDDLEVIGQYSSAAQAWSALI
                     RDDVNVAVIDIAMPDENGLSLLKRLRAQKPQFRAIILSIYDAPTFVQSALDAGASGYL
                     TKRCGPEELVQAVRSVGLGGHYLCADAIRALRGGGQPAQALEILTPREREVFELLVKG
                     DSVKEIAFKLELSHKTVHVHRANVLGKLNCHSTIELVHFALDHHLLAGH"
     misc_feature    complement(445309..445905)
                     /locus_tag="ECs_0418"
                     /note="DNA-binding response regulator, NarL/FixJ family,
                     contains REC and HTH domains [Signal transduction
                     mechanisms, Transcription]; Region: CitB; COG2197"
                     /db_xref="CDD:225107"
     gene            446235..447197
                     /gene="tauA"
                     /locus_tag="ECs_0419"
                     /db_xref="GeneID:914521"
     CDS             446235..447197
                     /gene="tauA"
                     /locus_tag="ECs_0419"
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter periplasmic binding
                     protein"
                     /protein_id="NP_308446.1"
                     /db_xref="GeneID:914521"
                     /translation="MAISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNT
                     FAKESGATVDWRKFDSGASIVRALASGDVQIGNLGSSPLAVAASQQVPIEVFLLASKL
                     GNSEALVVKKTISKPEDLIGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPA
                     IIAAWQRGDIDGAYVWAPAVNALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHP
                     EVVKAFSKSAIDAQQPYIANPDVWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQ
                     QQTAELTGPVNKAIIDTAQFLKEQGKVPAVANDYSQYVTSRFVQ"
     misc_feature    446235..447194
                     /gene="tauA"
                     /locus_tag="ECs_0419"
                     /note="taurine transporter substrate binding subunit;
                     Provisional; Region: tauA; PRK11480"
                     /db_xref="CDD:183158"
     misc_feature    order(446325..446327,446415..446417,446550..446552,
                     446616..446618,446631..446633,446757..446762,
                     446769..446771,446847..446849)
                     /gene="tauA"
                     /locus_tag="ECs_0419"
                     /note="putative chemical substrate binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:270278"
     gene            447210..447977
                     /gene="tauB"
                     /locus_tag="ECs_0420"
                     /db_xref="GeneID:914522"
     CDS             447210..447977
                     /gene="tauB"
                     /locus_tag="ECs_0420"
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter ATPase"
                     /protein_id="NP_308447.1"
                     /db_xref="GeneID:914522"
                     /translation="MLQISHLYADYGGKPVLEDINLTLESGELLVVLGPSGCGKTTLL
                     NLIAGFVPYQHGSIQLAGKRIEGPGAERGVVFQNEGLLPWRNVQDNVAFGLQLAGIEK
                     MQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALD
                     AFTRDQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSPGPGRVLERLPLNFA
                     RRFVAGESSRSIKSDPQFIAMREYVLSRVFEQREAFS"
     misc_feature    447210..447974
                     /gene="tauB"
                     /locus_tag="ECs_0420"
                     /note="taurine ABC transporter ATP-binding subunit;
                     Region: tauB; PRK11248"
                     /db_xref="CDD:183056"
     gene            447974..448801
                     /gene="tauC"
                     /locus_tag="ECs_0421"
                     /db_xref="GeneID:914523"
     CDS             447974..448801
                     /gene="tauC"
                     /locus_tag="ECs_0421"
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter permease"
                     /protein_id="NP_308448.1"
                     /db_xref="GeneID:914523"
                     /translation="MSVLINEKLHSRRLKWRWPLSRQVTLSIGTLAVLLTVWWTVAAL
                     QLISPLFLPPPQQVLAKLLTIAGPQGFMDATLWQHLAASLTRIVLALLAAVLIGIPVG
                     IAMGLSPTVRGILDPIIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS
                     ALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAE
                     LIAATRGLGFMVQSAGEFLATDVVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ"
     misc_feature    447974..448798
                     /gene="tauC"
                     /locus_tag="ECs_0421"
                     /note="taurine ABC transporter permease TauC; Region:
                     PRK10160"
                     /db_xref="CDD:182276"
     misc_feature    order(448334..448378,448607..448624)
                     /gene="tauC"
                     /locus_tag="ECs_0421"
                     /note="conserved gate region [active]"
                     /db_xref="CDD:119394"
     misc_feature    order(448484..448522,448538..448543,448553..448555)
                     /gene="tauC"
                     /locus_tag="ECs_0421"
                     /note="ABC-ATPase subunit interface [active]"
                     /db_xref="CDD:119394"
     gene            448798..449649
                     /gene="tauD"
                     /locus_tag="ECs_0422"
                     /db_xref="GeneID:914524"
     CDS             448798..449649
                     /gene="tauD"
                     /locus_tag="ECs_0422"
                     /codon_start=1
                     /transl_table=11
                     /product="taurine dioxygenase"
                     /protein_id="NP_308449.1"
                     /db_xref="GeneID:914524"
                     /translation="MSERLSITPLGPYIGAQISGADLTRPLSDNQFEQLYHAVLRHQV
                     VFLRDQAITPQQQRALAQRFGELHIHPVYPHAEGVDEIIVLDTHNDNPPDNDNWHTDV
                     TFIETPPAGAILAAKELPSTGGDTLWTSGIAAYEALSVPFRQLLSGLRAEHDFRKSFP
                     EYKYRKTEEEHQRWREAVAKNPPLLHPVVRTHPVSGKQALFVNEGFTTRIVDVSEKES
                     EALLGFLFAHITKPEFQVRWRWQPNDIAIWDNRVTQHYANADYLPQRRIMHRATILGD
                     KPFYRAG"
     misc_feature    448804..449634
                     /gene="tauD"
                     /locus_tag="ECs_0422"
                     /note="taurine dioxygenase; Reviewed; Region: tauD;
                     PRK09553"
                     /db_xref="CDD:181947"
     misc_feature    order(449092..449094,449098..449100,449173..449175,
                     449560..449562)
                     /gene="tauD"
                     /locus_tag="ECs_0422"
                     /note="active site"
                     /db_xref="CDD:238154"
     misc_feature    order(449092..449094,449098..449100,449560..449562)
                     /gene="tauD"
                     /locus_tag="ECs_0422"
                     /note="iron coordination sites [ion binding]; other site"
                     /db_xref="CDD:238154"
     gene            complement(449756..450730)
                     /gene="hemB"
                     /locus_tag="ECs_0423"
                     /db_xref="GeneID:914525"
     CDS             complement(449756..450730)
                     /gene="hemB"
                     /locus_tag="ECs_0423"
                     /codon_start=1
                     /transl_table=11
                     /product="5-aminolevulinate dehydratase"
                     /protein_id="NP_308450.2"
                     /db_xref="GeneID:914525"
                     /translation="MTDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDY
                     KAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARM
                     SRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGAD
                     FIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKS
                     YQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEY
                     AMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR"
     misc_feature    complement(449774..450730)
                     /gene="hemB"
                     /locus_tag="ECs_0423"
                     /note="porphobilinogen synthase; Region: PRK09283"
                     /db_xref="CDD:236450"
     misc_feature    complement(order(449822..449824,449831..449833,
                     449843..449845,449897..449899,449969..449983,
                     450035..450040,450047..450049,450065..450067,
                     450074..450076,450131..450139,450224..450229,
                     450308..450313,450578..450580,450587..450589,
                     450659..450661,450692..450697,450704..450706))
                     /gene="hemB"
                     /locus_tag="ECs_0423"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238226"
     misc_feature    complement(order(449795..449797,449912..449914,
                     449921..449923,449990..449992,450071..450073,
                     450083..450085,450101..450103,450116..450121,
                     450128..450130,450146..450148,450236..450238,
                     450341..450343,450365..450367,450371..450373,
                     450377..450379))
                     /gene="hemB"
                     /locus_tag="ECs_0423"
                     /note="active site"
                     /db_xref="CDD:238226"
     misc_feature    complement(order(449990..449992,450146..450148))
                     /gene="hemB"
                     /locus_tag="ECs_0423"
                     /note="Schiff base residues [active]"
                     /db_xref="CDD:238226"
     gene            451256..454198
                     /gene="yaiT"
                     /locus_tag="ECs_0424"
                     /db_xref="GeneID:914526"
     CDS             451256..454198
                     /gene="yaiT"
                     /locus_tag="ECs_0424"
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin structural protein"
                     /protein_id="NP_308451.1"
                     /db_xref="GeneID:914526"
                     /translation="MHSWKKKLIVSQLALACTLAITSQANAATNDISGQTYNTFHHYN
                     DATYADDVYYDGYVGWNNYAADSYYNGDIYPVINNATVNGVISTYYLDDGISTNTNAN
                     SLTIKNSTIHGMITSECMTTDCADDRATGYVYDRLTLSVDNSTIDDNYEHYTYNGTYN
                     NAADTHVVDVYDMGTAITLDQEVDLSITNNSHVAGITLTQGYEWEDIDDNTVSTGVNS
                     SEVFNNTITVKDSTVTSGSWTDEGTTGWFGHTGNASNYSNTLTADDVAIAAIANPYAD
                     NAMQTTVTLDNSTLMGDVVFSSNFDENFFPQGANSYRDADGDVDTNGWDGTDRMDVTL
                     NNGSKWVGAAMSVHMVDEDGDGSYDGYAVGTEATATLLDIAANSLWPSSTVGVDNINT
                     QYDENGHIVGNEVYQSGLFNVTLNGGSEWDTTKSSLIDTLSINSGSQVNVADSRLISD
                     TVSLTGGSNLNIGEDGHVATNTLTIDNSTVKMSDDVSAGWGLEDAALYANTITVTNDG
                     LLDINVDQFDANPFQADTLNLTSTTDTNGNIHAGVFDIHSSDYVMDTDLVNDRTNDTT
                     KSNYGYGLIAMNSDGHLTINGNGDNDNTASIEAGQNEVDNNGDHVAAATGNYKVRIDN
                     ATGAGSIADYNGNELIYVNDKNSNATFSAANKADLGAYTYQAEQRGNTVVLQQMELTD
                     YANMALSIPSANTNIWNLEQDTVGTRLTNSRHGLADNGGAWVSYFGGNFNGDNGTINY
                     DQDVNGIMVGVDTKIDGNNAKWIVGAAAGFAKGDMNDRSGQVDQDSQTAYIYSSAHFA
                     NNVFVDGSLSYSHFNNDLSATMSNGTYVDGSTNSDAWGFGLKAGYDFKLGDAGYVTPY
                     GSISGLFQSGDDYQLSNDMKVDGQSYDSMRYELGVDAGYTFTYSEDQALTPYFKLAYV
                     YDDSNNDNDVNGDSIDNGTEGSAVRVGLGTQFSFTKNFSAYTDANYLGGGDVDQDWSA
                     NVGVKYTW"
     misc_feature    452957..454195
                     /gene="yaiT"
                     /locus_tag="ECs_0424"
                     /note="outer membrane autotransporter barrel domain;
                     Region: autotrans_barl; TIGR01414"
                     /db_xref="CDD:273608"
     gene            454286..454909
                     /gene="yaiV"
                     /locus_tag="ECs_0425"
                     /db_xref="GeneID:914527"
     CDS             454286..454909
                     /gene="yaiV"
                     /locus_tag="ECs_0425"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_308452.2"
                     /db_xref="GeneID:914527"
                     /translation="MLSVVKPLQEFGKLDKCLSRYGTRFEFNNEKQVIFSSDVNNEDT
                     FVILEGVISLRREENVLIGITQAPYIMGLADGLMKNDIPYKLISEGNCTGYHLPAKQT
                     ITLIEQNQLWRDAFYWLAWQNRILELRDVQLIGHNSYEQIRATLLSMIDWNEELRSRI
                     GVMNYIHQRTRISRSVVAEVLAALRKGGYIEMNKGKLVAINRLPSEY"
     misc_feature    454286..454906
                     /gene="yaiV"
                     /locus_tag="ECs_0425"
                     /note="hydrogen peroxide resistance inhibitor IprA;
                     Region: PRK11832"
                     /db_xref="CDD:183332"
     gene            complement(454910..456067)
                     /gene="ampH"
                     /locus_tag="ECs_0426"
                     /db_xref="GeneID:914528"
     CDS             complement(454910..456067)
                     /gene="ampH"
                     /locus_tag="ECs_0426"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine-
                     carboxypeptidase/endopeptidase"
                     /protein_id="NP_308453.1"
                     /db_xref="GeneID:914528"
                     /translation="MKRSLLFSAVLCAASLTSVHAAQPITEPEFASDIVDRYADHIFY
                     GSGATGMALVVIDGNQRVFRSYGETRPGNNVRPQLDSVVRIASLTKLMTSEMLVKLLD
                     QGTVKLNDPLSKYAPPGARVPTYNGTPITLVNLATHTSALPREQPGGAAHRPVFVWPT
                     REQRWKYLSTAKLKAAPGSQAAYSNLAFDLLADALANASGKPYTQLFEEQITRPLGMK
                     DTTYTPSPDQCRRLMVAERGASPCNNTLAAIGSGGVYSTPGDMMRWMQQYLSSDFYQR
                     SNQADRMQTLIYQRAQFTKVIGMDVPGKADALGLGWVYMAPKEGRPGIIQKTGGGGGF
                     ITYMAMIPQKNIGAFVVVTRSPLTRFKNMSDGINDLVTELSGNKPLVIPAS"
     misc_feature    complement(454934..456067)
                     /gene="ampH"
                     /locus_tag="ECs_0426"
                     /note="beta-lactam binding protein AmpH; Provisional;
                     Region: PRK10662"
                     /db_xref="CDD:236732"
     gene            456419..457639
                     /gene="sbmA"
                     /locus_tag="ECs_0427"
                     /db_xref="GeneID:914529"
     CDS             456419..457639
                     /gene="sbmA"
                     /locus_tag="ECs_0427"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide antibiotic transporter"
                     /protein_id="NP_308454.1"
                     /db_xref="GeneID:914529"
                     /translation="MFKSFFPKPGTFFLSAFVWALIAVIFWQAGGGDWVARITGASGQ
                     IPISAARFWSLDFLIFYAYYIVCVGLFALFWFIYSPHRWQYWSILGTALIIFVTWFLV
                     EVGVAVNAWYAPFYDLIQTALSSPHKVTIEQFYREVGVFLGIALIAVVISVLNNFFVS
                     HYVFRWRTAMNEYYMANWQQLRHIEGAAQRVQEDTMRFASTLENMGVSFINAIMTLIA
                     FLPVLVTLSAHVPELPIIGHIPYGLVIAAIVWSLMGTGLLAVVGIKLPGLEFKNQRVE
                     AAYRKELVYGEDDATRATPPTVRELFSAVRKNYFRLYFHYMYFNIARILYLQVDNVFG
                     LFLLFPSIVAGTITLGLMTQITNVFGQVRGAFQYLINSWTTLVELMSIYKRLRSFEHE
                     LDGDKIQEVTHTLS"
     misc_feature    456419..457636
                     /gene="sbmA"
                     /locus_tag="ECs_0427"
                     /note="peptide antibiotic transporter SbmA; Region:
                     PRK11098"
                     /db_xref="CDD:182960"
     gene            457652..458746
                     /gene="yaiW"
                     /locus_tag="ECs_0428"
                     /db_xref="GeneID:914530"
     CDS             457652..458746
                     /gene="yaiW"
                     /locus_tag="ECs_0428"
                     /codon_start=1
                     /transl_table=11
                     /product="microcin Bac7 uptake protein"
                     /protein_id="NP_308455.1"
                     /db_xref="GeneID:914530"
                     /translation="MSRVNHLSSLSFLAVLVLAGCSSQAPQPLKKGEKAIDVASVVRQ
                     KMPASVKDRDAWAKDLATTFESQGLAPTLENVCSVLAVAQQESNYQADPAVPGLSKIA
                     WQEIDRRAERMHIPAFLVHTALKIKSPNGKSYSERLDSVRTEKQLSGIFDDLISMVPM
                     GQTLFGSLNPVRTGGPMQVSIAFAEQHTKGYPWKMDGTVRQEVFSRRGGLWFGTYHLL
                     NYPASYSAPIYRFADFNAGWYASRNAAFQNAVSKASGVKLALDGDLIRYDSKEPGKTE
                     LATRKLAAKLGMSDSEIRRQLEKGDSFSFEETALYKKVYQLAEAKTGKSLPREMLPGI
                     QLESPKITRNLTTAWFAKRVDERRARCMKQ"
     misc_feature    457796..458740
                     /gene="yaiW"
                     /locus_tag="ECs_0428"
                     /note="Protein of unknown function (DUF1615); Region:
                     DUF1615; pfam07759"
                     /db_xref="CDD:429641"
     gene            complement(458805..459113)
                     /gene="yaiY"
                     /locus_tag="ECs_0429"
                     /db_xref="GeneID:914531"
     CDS             complement(458805..459113)
                     /gene="yaiY"
                     /locus_tag="ECs_0429"
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein"
                     /protein_id="NP_308456.1"
                     /db_xref="GeneID:914531"
                     /translation="MADFTLSKSLFSGKYRNASSTPGNIAYALFVLFCFWAGAQLLNL
                     LVHAPGVYERLMQVQETGRPRVEIGLGVGTIFGLIPFLVGCLIFAVVALWLHWRHRRQ
                     "
     misc_feature    complement(458811..459113)
                     /gene="yaiY"
                     /locus_tag="ECs_0429"
                     /note="Protein of unknown function (DUF2755); Region:
                     DUF2755; pfam10954"
                     /db_xref="CDD:402505"
     gene            459373..459585
                     /gene="yaiZ"
                     /locus_tag="ECs_0430"
                     /db_xref="GeneID:914532"
     CDS             459373..459585
                     /gene="yaiZ"
                     /locus_tag="ECs_0430"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308457.2"
                     /db_xref="GeneID:914532"
                     /translation="MNLPVKIRRDWHYYAFAIGLIFILNGVVGLLGFEAKGWQTYAVG
                     LVTWVISFWLAGLIIRRRDEETENAQ"
     misc_feature    459373..459582
                     /gene="yaiZ"
                     /locus_tag="ECs_0430"
                     /note="Protein of unknown function (DUF2754); Region:
                     DUF2754; pfam10953"
                     /db_xref="CDD:402504"
     gene            complement(459609..460703)
                     /gene="ddlA"
                     /locus_tag="ECs_0431"
                     /db_xref="GeneID:914533"
     CDS             complement(459609..460703)
                     /gene="ddlA"
                     /locus_tag="ECs_0431"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine-D-alanine ligase A"
                     /protein_id="NP_308458.1"
                     /db_xref="GeneID:914533"
                     /translation="MEKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKSRFDVVLLGID
                     KQGQWHVSDASNYLLNADDPAHIALRPSATSLAQVPGKHEHQLIDAQNGQPLPTVDVI
                     FPIVHGTLGEDGSLQGMLRVANLPFVGSDVLASAACMDKDVTKRLLRDAGLNIAPFIT
                     LTRANRHNISFAEVESKLGLPLFVKPANQGSSVGVSKVTSEEQYAIAVDLAFEFDHKV
                     IVEQGIKGREIECAVLGNDNPQASTCGEIVLTSDFYAYDTKYIDEDGAKVVVPAAIAP
                     EINDKIRAIAVQAYQTLGCAGMARVDVFLTPENEVVINEINTLPGFTNISMYPKLWQA
                     SGLGYTDLITRLIELALERHAADNALKTTM"
     misc_feature    complement(459648..460703)
                     /gene="ddlA"
                     /locus_tag="ECs_0431"
                     /note="D-alanine--D-alanine ligase; Region: ddl; PRK01966"
                     /db_xref="CDD:234993"
     gene            461166..461426
                     /gene="iraP"
                     /locus_tag="ECs_0432"
                     /db_xref="GeneID:914534"
     CDS             461166..461426
                     /gene="iraP"
                     /locus_tag="ECs_0432"
                     /codon_start=1
                     /transl_table=11
                     /product="anti-RssB factor"
                     /protein_id="NP_308459.1"
                     /db_xref="GeneID:914534"
                     /translation="MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQND
                     QQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKLLKHPRQ"
     misc_feature    461166..461423
                     /gene="iraP"
                     /locus_tag="ECs_0432"
                     /note="anti-adapter protein IraP; Region: PRK10244"
                     /db_xref="CDD:236666"
     gene            461527..462942
                     /gene="phoA"
                     /locus_tag="ECs_0433"
                     /db_xref="GeneID:914535"
     CDS             461527..462942
                     /gene="phoA"
                     /locus_tag="ECs_0433"
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial alkaline phosphatase"
                     /protein_id="NP_308460.2"
                     /db_xref="GeneID:914535"
                     /translation="MKQSTIALALLPLLFTPVTKARTPEMPVLENRAAQGDITAPGGA
                     RRLTADQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPL
                     TGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKA
                     AGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLL
                     NARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKP
                     LLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSK
                     NEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKDGNTLVIVTADH
                     AHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAAN
                     VVGLTDQTDLFYTMKAALGLK"
     misc_feature    461527..462939
                     /gene="phoA"
                     /locus_tag="ECs_0433"
                     /note="alkaline phosphatase; Provisional; Region:
                     PRK10518"
                     /db_xref="CDD:236706"
     gene            463061..463381
                     /gene="psiF"
                     /locus_tag="ECs_0434"
                     /db_xref="GeneID:914536"
     CDS             463061..463381
                     /gene="psiF"
                     /locus_tag="ECs_0434"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PsiF"
                     /protein_id="NP_308461.2"
                     /db_xref="GeneID:914536"
                     /translation="MKITLLVTLLFGLVFLTTVGAAERTLTPQQQRMTSCNQQATAQA
                     LKGDARKTYMSDCLKNSKSAPGEKSLTPQQQKMRECNNQATQQSLKGDDRNKFMSACL
                     KKAA"
     misc_feature    463061..463378
                     /gene="psiF"
                     /locus_tag="ECs_0434"
                     /note="phosphate starvation-inducible protein PsiF;
                     Region: PRK11505"
                     /db_xref="CDD:183165"
     gene            463483..464598
                     /gene="yaiC"
                     /locus_tag="ECs_0435"
                     /db_xref="GeneID:914537"
     CDS             463483..464598
                     /gene="yaiC"
                     /locus_tag="ECs_0435"
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="NP_308462.1"
                     /db_xref="GeneID:914537"
                     /translation="MFPKIMNDENFFKKAAAHGEEPPLTPQNEHQRSGLRFARRVRLP
                     RAVGLAGMFLPIASTLVSHPPPGWWWLVLVGWAFVWPHLAWQIASRAVDPLSREIYNL
                     KTDAVLAGMWVGVMGVNVLPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLEL
                     TGITVSFNSAPLEWWLSLPIIVIYPLLFGWVSYQTATKLAEHKRRLQVMSTRDGMTGV
                     YNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQLQ
                     ITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVHEGLNTLRLPNTPQVNLRISVG
                     VAPLNPQMSHYREWLKSADLALYKAKKAGRNRTEVAA"
     misc_feature    463498..464595
                     /gene="yaiC"
                     /locus_tag="ECs_0435"
                     /note="diguanylate cyclase AdrA; Provisional; Region:
                     adrA; PRK10245"
                     /db_xref="CDD:182329"
     gene            complement(464615..465424)
                     /gene="proC"
                     /locus_tag="ECs_0436"
                     /db_xref="GeneID:914539"
     CDS             complement(464615..465424)
                     /gene="proC"
                     /locus_tag="ECs_0436"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="NP_308464.3"
                     /db_xref="GeneID:914539"
                     /translation="MEKKIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVAA
                     LHDKFGINAAESAQEVAQIADIIFAAVKPGIMIKVLSEITSSLNKDSLVVSIAAGVTL
                     DQLARALGHDRKIIRAMPNTPALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVI
                     AEPMIHPVVGVSGSSPAYVFMFIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLET
                     GEHPGALKDMVCSPGGTTIEAVRVLEEKGFRAAVIEAMTKCMEKSEKLSKS"
     misc_feature    complement(464618..465424)
                     /gene="proC"
                     /locus_tag="ECs_0436"
                     /note="pyrroline-5-carboxylate reductase; Reviewed;
                     Region: PRK11880"
                     /db_xref="CDD:237008"
     gene            465544..466002
                     /gene="yaiI"
                     /locus_tag="ECs_0437"
                     /db_xref="GeneID:914538"
     CDS             465544..466002
                     /gene="yaiI"
                     /locus_tag="ECs_0437"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308463.2"
                     /db_xref="GeneID:914538"
                     /translation="MTIWVDADACPNVIKEILYRAAERMQMPLVLVANQSLRVPPSRF
                     IRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEAIEKGAAALNPRGERYTPATI
                     RERLTMRDFMDTLRASGIQTGGPDSLSQRDRQAFAAELEKWWLEVQRSRG"
     misc_feature    465544..465996
                     /gene="yaiI"
                     /locus_tag="ECs_0437"
                     /note="YaiI/YqxD family protein; Region: PRK00124"
                     /db_xref="CDD:178882"
     gene            466185..466709
                     /gene="aroL"
                     /locus_tag="ECs_0438"
                     /db_xref="GeneID:914540"
     CDS             466185..466709
                     /gene="aroL"
                     /locus_tag="ECs_0438"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase II"
                     /protein_id="NP_308465.1"
                     /db_xref="GeneID:914540"
                     /translation="MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMT
                     VAEIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCA
                     PVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQV
                     ISEIRSALAQTINC"
     misc_feature    466185..466694
                     /gene="aroL"
                     /locus_tag="ECs_0438"
                     /note="shikimate kinase AroL; Region: aroL; PRK03731"
                     /db_xref="CDD:235153"
     misc_feature    order(466218..466235,466512..466514,466542..466544)
                     /gene="aroL"
                     /locus_tag="ECs_0438"
                     /note="ADP binding site [chemical binding]; other site"
                     /db_xref="CDD:238260"
     misc_feature    order(466230..466232,466278..466280,466284..466286)
                     /gene="aroL"
                     /locus_tag="ECs_0438"
                     /note="magnesium binding site [ion binding]; other site"
                     /db_xref="CDD:238260"
     misc_feature    order(466284..466286,466356..466358,466365..466367,
                     466416..466424,466599..466601)
                     /gene="aroL"
                     /locus_tag="ECs_0438"
                     /note="putative shikimate binding site [active]"
                     /db_xref="CDD:238260"
     gene            466759..466950
                     /gene="yaiA"
                     /locus_tag="ECs_0439"
                     /db_xref="GeneID:914541"
     CDS             466759..466950
                     /gene="yaiA"
                     /locus_tag="ECs_0439"
                     /codon_start=1
                     /transl_table=11
                     /product="OxyR-regulated protein"
                     /protein_id="NP_308466.1"
                     /db_xref="GeneID:914541"
                     /translation="MPTKPPYPREAYIVTIEKGKPGQTVTWYQLRADHPKPDSLISEH
                     PTAQEAMDAKKRYEDPDKE"
     misc_feature    466759..466947
                     /gene="yaiA"
                     /locus_tag="ECs_0439"
                     /note="hypothetical protein; Provisional; Region:
                     PRK10380"
                     /db_xref="CDD:182421"
     gene            467208..467885
                     /gene="aroM"
                     /locus_tag="ECs_0440"
                     /db_xref="GeneID:914542"
     CDS             467208..467885
                     /gene="aroM"
                     /locus_tag="ECs_0440"
                     /codon_start=1
                     /transl_table=11
                     /product="AroM family protein"
                     /protein_id="NP_308467.1"
                     /db_xref="GeneID:914542"
                     /translation="MSASLAILTIGIVPMQEVLPLLTEYIDEDNISHHSLLGKLSREE
                     VMAEYAPEAGEDTILTLLNDNHLAHVSRRKVERDLQGVVEVLDNQGYDVIILMSTANI
                     SSMTARNTIFLEPSRILPPLVSSIVEDHQVGVIVPVEELLTVQAQKWQILQKPPVFSL
                     GNPIHDSEQKIIDAGKELLAKGADVIMLDCLGFNQRHRDLLQKQLDVPVLLSNVLIAR
                     LAAELLV"
     misc_feature    467208..467879
                     /gene="aroM"
                     /locus_tag="ECs_0440"
                     /note="hypothetical protein; Provisional; Region:
                     PRK10481"
                     /db_xref="CDD:182491"
     gene            467957..468241
                     /gene="yaiE"
                     /locus_tag="ECs_0441"
                     /db_xref="GeneID:914543"
     CDS             467957..468241
                     /gene="yaiE"
                     /locus_tag="ECs_0441"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308468.1"
                     /db_xref="GeneID:914543"
                     /translation="MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEE
                     MTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL"
     misc_feature    467957..468238
                     /gene="yaiE"
                     /locus_tag="ECs_0441"
                     /note="pyrimidine/purine nucleoside phosphorylase; Region:
                     PRK10579"
                     /db_xref="CDD:182565"
     gene            468385..470664
                     /gene="ydbD"
                     /locus_tag="ECs_0442"
                     /db_xref="GeneID:914544"
     CDS             468385..470664
                     /gene="ydbD"
                     /locus_tag="ECs_0442"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308469.2"
                     /db_xref="GeneID:914544"
                     /translation="MNRINILVICMVLFFMTGNACATEWISSEDLITSDFHLMTADER
                     NVVKAATDDSMEAAYMLKDNIRWYYHNGDLSLPANFSNKNKLVVNGNLTISGDYDDYL
                     SGNGHLIVLGNVIVDNFINHDFAYVKGQMTAKGLVYADYNDHNFEVMKGISARGIIVS
                     DKATQFEVIKAEFYINEDGSGEGYNWDENIQKAYSLVTADLYDHTEIETDNISNAYPD
                     YDSVADNIVQGLPLFRDKAAPEINEKLKWIETGKLDNFPANKIKHQDPLVARFLTHTE
                     SLSPAVMLQLLQHPDDQTRESMAQSWPAQQMHWLTDELIKDEAVARGLVKNSNISADV
                     NKKLMSVPVESVQLEQARQDNLSPDIVASLSHSPFLSVRKTLLSHYDYAWLVPTAVAD
                     ELINNEDPELRERITGADLTAQQAVMLSKDKSLKVREALARTLTELKITQLSATLRTE
                     DIERIAEQMYLDNKENKNIVKVLLIALPEMCQLSLAKEDVHNLREGARYLTSKDVISY
                     LLTQHDVPTVWDELARDKLLPLEYKKQLWQRTLNLMMSKRQEDQEQAYEVQLALIDNG
                     VVDEEMLNNAIDLLVDLPAEYRYRMRNQLFDNKELPSGIINKLDQQYRFNSDWALAVV
                     SMKNSTRRQSERGLHRWNHEDSDIFAELATIKDKSDDEWWRALLQSRNDHLRQTALRN
                     AHTPASLLTTLTESQDRSLAINNPQLAADVKTVWLKEDPSLLLFVDKPDLSQLRDLVK
                     TGATRKIRNEARHRLEEKQ"
     misc_feature    470419..470661
                     /gene="ydbD"
                     /locus_tag="ECs_0442"
                     /note="Protein of unknown function (DUF2773); Region:
                     DUF2773; pfam10971"
                     /db_xref="CDD:287885"
     gene            470661..471110
                     /locus_tag="ECs_0443"
                     /db_xref="GeneID:914545"
     CDS             470661..471110
                     /locus_tag="ECs_0443"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308470.1"
                     /db_xref="GeneID:914545"
                     /translation="MTQRPWSKLQREIYDLLTPTINLQIHCTRYPMRSQNGGSTDLPR
                     YWITLDKNVIWDYPKDFIAGNGGVRNFHGETCWYPYLTDICSISDLLREYIDTPKAEL
                     LTKQFTSDKWGLVNILRAADRRIGMRRLDQLRRKTHNIAALKNYCPP"
     gene            complement(471195..472172)
                     /gene="rdgC"
                     /locus_tag="ECs_0444"
                     /db_xref="GeneID:914547"
     CDS             complement(471195..472172)
                     /gene="rdgC"
                     /locus_tag="ECs_0444"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-associated protein rdgC"
                     /protein_id="NP_308472.3"
                     /db_xref="GeneID:914547"
                     /translation="MQGRRQFVIMPAKFNDKAVEIIMLWFKNLMVYRLSREISLRAEE
                     MEKQLASMAFTPCGSQDMAKMGWVPPMGSHSDALTHVANGQIVICARKEEKILPSPVI
                     KQALEAKIAKLEAEQARKLKKTEKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIM
                     VDCASAKKAEDTLALLRKSLGSLPVVPLSMANPIELTLTEWVRSGSAAQGFQLLDEAE
                     LKSLLEDGGVIRAKKQDLTSEEITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLK
                     FCDELRDQNEDIDREDFAQRFDADFILMTGELAALIQNLIEGLGGEAQR"
     misc_feature    complement(471198..472103)
                     /gene="rdgC"
                     /locus_tag="ECs_0444"
                     /note="DNA recombination-dependent growth factor C
                     [Replication, recombination and repair]; Region: RdgC;
                     COG2974"
                     /db_xref="CDD:225521"
     gene            472231..473139
                     /gene="mak"
                     /locus_tag="ECs_0445"
                     /db_xref="GeneID:914546"
     CDS             472231..473139
                     /gene="mak"
                     /locus_tag="ECs_0445"
                     /codon_start=1
                     /transl_table=11
                     /product="manno(fructo)kinase"
                     /protein_id="NP_308471.2"
                     /db_xref="GeneID:914546"
                     /translation="MRIGIDLGGTKTEVIALGDAGEQLYRHRLPTPRDDYRQTIETIA
                     TLVDMAEQATGQRGTVGMGIPGSISPYTGVVKNANSTWLNGQPFDKDLSARLQREVRL
                     ANDANCLAVSEAVDGAAAGAQTVFAVIIGTGCGAGVAFNGRAHIGGNGTAGEWGHNPL
                     PWMDEDELRYREEVPCYCGKQGCIETFISGTGFATDYRRLSGHALKGSEIIRLVEESD
                     PVAELALRRYELRLAKSLAHVVNILDPDVIVLGGGMSNVDRLYQTVPQLIKQFVFGGE
                     CETPVRKAKHGDSSGVRGAAWLWPQE"
     misc_feature    472231..473133
                     /gene="mak"
                     /locus_tag="ECs_0445"
                     /note="fructokinase; Reviewed; Region: PRK09557"
                     /db_xref="CDD:236565"
     misc_feature    order(472246..472257,472261..472263,472267..472269,
                     472543..472545,472615..472626)
                     /gene="mak"
                     /locus_tag="ECs_0445"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:212657"
     gene            complement(473282..474550)
                     /gene="araJ"
                     /locus_tag="ECs_0446"
                     /db_xref="GeneID:914548"
     CDS             complement(473282..474550)
                     /gene="araJ"
                     /locus_tag="ECs_0446"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose-inducible transporter"
                     /protein_id="NP_308473.4"
                     /db_xref="GeneID:914548"
                     /translation="MALLVVILQAITLLATVIGSRSGSCDGGMKKVILSLALGTFGLG
                     MAEFGIMGVLTELAHNVGISIPAAGHMISYYALGVVVGAPIIALFSSRYSLKHILLFL
                     VALCVIGNAMFTLSSSYLMLAIGRLVSGFPHGAFFGVGAIVLSKIIKPGKVTAAVAGM
                     VSGMTVANLLGIPLGTYLSQEFSWRYTFLLIAVFNIAVMASVYFWVPDIRDEAKGKLR
                     EQFHFLRSPAPWLIFAATMFGNAGVFAWFSYVKPYMMFISGFSETAMTFIMMLVGLGM
                     VLGNMLSGRISGRYSPLRIAAVTDFIIVLALLMLFFCGGMKTTSLIFAFICCAGLFAL
                     SAPLQILLLQNAKGGELLGAAGGQIAFNLGSAVGAYCGGMMLTLGLAYNYVALPAALL
                     SFAAMSSLLLYGRYKRQQAADSPVLAKPLG"
     misc_feature    complement(473321..474466)
                     /gene="araJ"
                     /locus_tag="ECs_0446"
                     /note="MFS transport protein AraJ; Provisional; Region:
                     PRK10091"
                     /db_xref="CDD:182234"
     gene            complement(474592..477735)
                     /gene="sbcC"
                     /locus_tag="ECs_0447"
                     /db_xref="GeneID:914549"
     CDS             complement(474592..477735)
                     /gene="sbcC"
                     /locus_tag="ECs_0447"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="NP_308474.2"
                     /db_xref="GeneID:914549"
                     /translation="MKILSLRLKNLNSLKGEWKIDFTREPFASNGLFAITGPTGAGKT
                     TLLDAICLALYHETPRLSNVSQSQNDLMTRDTAECLAEVEFEVKGEAYRAFWSQNRAR
                     NQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYGRFTRSMLLSQGQFAA
                     FLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVALLTPEQV
                     QSLTASLQVLTDEEKQLLTAQQQEQQSLNWLTRLDELQQEASRRQQALQQALAEEEKA
                     QPQLAALSLAQPARNLRPHWERIAEHSAALAHTRQQIEEVNTRLQNTMALRASIRHHA
                     AKQSAELQQQQQSLNTWLQEHDRFRQWNNELAGWRAQFSQQTSDREHLRQWQQQLTHA
                     EQKLNALAAITLMLTADEVATALAQHAEQRPLRQRLVALHGQIVPQQKRLAQLMVTIQ
                     NVTLEQTQRNAALNEMRQRYKEKTQQLADVKTICEQEARIKTLEAQRAQLQAGQPCPL
                     CGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEGAALRGQLDALTKQLQRDENE
                     AQSLRQDEQALTQQWQAVTASLNITLQPQDDIQPWLDAQDEHERQLRLLSQRHELQGQ
                     IAAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQEDEEESWLATRQQEAQSWQQRQN
                     ELTALQNRIQQLTPILETLPQSDDLPHSEETVALDNWRQVHEQCLALHSQQQTLQQQD
                     VLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQT
                     LVTQTAETLAQHQQHRPDGLALTVTVEQIQQELAQTHQKLRENTTSQGEIRQQLKQDA
                     DNRQQQQTLLQQIAQMTQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQL
                     TRLHGRYLLQRKASEALEVEVVDTWQADAVRDTRTLSGGESFLVSLALALALSDLVSH
                     KTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERIPVQIKVK
                     KINGLGYSKLESTFAVK"
     misc_feature    complement(474595..477735)
                     /gene="sbcC"
                     /locus_tag="ECs_0447"
                     /note="exonuclease subunit SbcC; Provisional; Region:
                     PRK10246"
                     /db_xref="CDD:182330"
     gene            complement(477732..478934)
                     /gene="sbcD"
                     /locus_tag="ECs_0448"
                     /db_xref="GeneID:914550"
     CDS             complement(477732..478934)
                     /gene="sbcD"
                     /locus_tag="ECs_0448"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="NP_308475.1"
                     /db_xref="GeneID:914550"
                     /translation="MRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQTHQVDAII
                     VAGDVFDTGSPPSYARTLYNRFVVNLQQTGCHLVVLAGNHDSVATLNESRDIMAFLNT
                     TVVASAGHAPQILPRRDGTPGAVLCPIPFLRPRDIITSQAGLNGIEKQQHLLAAITDY
                     YQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFPAQNFPPADYI
                     ALGHIHRAQIIGGMEHVRYCGSPIPLSFDECGKSKYVHLVTFSNGKLESVENLNVPVT
                     QPMAVLKGDLASITAQLEQWRDVSQEPPVWLDIEITTDEYLHDIQRKIQALTESLPVE
                     VLLVRRSREQRERVLASQQRETLSELSVEEVFNRRLALEELDESQQQRLQHLFTTTLH
                     TLAGEHEA"
     misc_feature    complement(477735..478934)
                     /gene="sbcD"
                     /locus_tag="ECs_0448"
                     /note="exonuclease subunit SbcD; Provisional; Region:
                     PRK10966"
                     /db_xref="CDD:182871"
     gene            479124..479813
                     /gene="phoB"
                     /locus_tag="ECs_0449"
                     /db_xref="GeneID:914551"
     CDS             479124..479813
                     /gene="phoB"
                     /locus_tag="ECs_0449"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component regulatory system response
                     regulator PhoB"
                     /protein_id="NP_308476.1"
                     /db_xref="GeneID:914551"
                     /translation="MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNE
                     PWPDLILLDWMLPGGSGIQFIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDY
                     ITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPTSHRVMAGEEPLEMGPTEF
                     KLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEPGGHDRMVQTV
                     RGTGYRFSTRF"
     misc_feature    479124..479810
                     /gene="phoB"
                     /locus_tag="ECs_0449"
                     /note="phosphate response regulator transcription factor
                     PhoB; Region: PRK10161"
                     /db_xref="CDD:182277"
     gene            479871..481166
                     /gene="phoR"
                     /locus_tag="ECs_0450"
                     /db_xref="GeneID:914552"
     CDS             479871..481166
                     /gene="phoR"
                     /locus_tag="ECs_0450"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PhoR"
                     /protein_id="NP_308477.1"
                     /db_xref="GeneID:914552"
                     /translation="MLERLSWKRLVLELLLCCLPAFILGAFFGYLPWFLLASVTGLLI
                     WHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRELGNLIKRFRS
                     GAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEFTQYLKTRD
                     FSRPLNLVLNTGRHLEIRVMPYTHKQLLMVARDVTQMHQLEGARRNFFANVSHELRTP
                     LTVLQGYLEMMDEQPLEGAVREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTQLLNE
                     KVDVPMMLRVVEREAQTLSQKKQTFTFEIDNGLKVSGNEDQLRSVISNLVYNAVNHTP
                     EGTHITVRWQRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLA
                     IVKHAVNHHESRLNIESTVGKGTRFSFVIPERLIVKNSD"
     misc_feature    479871..481160
                     /gene="phoR"
                     /locus_tag="ECs_0450"
                     /note="phosphate regulon sensor histidine kinase PhoR;
                     Region: phoR; PRK11006"
                     /db_xref="CDD:182895"
     gene            481573..482892
                     /gene="brnQ"
                     /locus_tag="ECs_0451"
                     /db_xref="GeneID:914553"
     CDS             481573..482892
                     /gene="brnQ"
                     /locus_tag="ECs_0451"
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid transport system II
                     carrier protein"
                     /protein_id="NP_308478.1"
                     /db_xref="GeneID:914553"
                     /translation="MTHQLRSRDIIALGFMTFALFVGAGNIIFPPMVGLQAGEHVWTA
                     AFGFLITAVGLPVLTVVALAKVGGGVDSLSTPIGKVAGVLLATVCYLAVGPLFATPRT
                     ATVSFEVGIAPLTGDSALPLFIYSLVYFAIVILVSLYPGKLLDTVGNFLAPLKIIALV
                     ILSVAAIVWPAGSISTATEAYQNAAFSNGFVNGYLTMDTLGAMVFGIVIVNAARSRGV
                     TEARLLTRYTVWAGLMAGVGLTLLYLALFRLGSDSASLVDQSANGAAILHAYVQHTFG
                     GGGSFLLAALIFIACLVTAVGLTCACAEFFAQYVPLSYRTLVFILGGFSMVVSNLGLS
                     QLIQISVPVLTAIYPPCIALVVLSFTRSWWHNSSRVIAPPMFISLLFGILDGIKASAF
                     SDILPSWAQRLPLAEQGLAWLMPTVVMVVLAIIWDRAAGRQVTSSAH"
     misc_feature    481573..482889
                     /gene="brnQ"
                     /locus_tag="ECs_0451"
                     /note="branched-chain amino acid transporter carrier
                     protein BrnQ; Region: PRK15433"
                     /db_xref="CDD:185331"
     gene            482968..484341
                     /gene="proY"
                     /locus_tag="ECs_0452"
                     /db_xref="GeneID:914554"
     CDS             482968..484341
                     /gene="proY"
                     /locus_tag="ECs_0452"
                     /codon_start=1
                     /transl_table=11
                     /product="proline-specific permease"
                     /protein_id="NP_308479.1"
                     /db_xref="GeneID:914554"
                     /translation="MESKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSV
                     LLAYIIGGIAAYIIMRALGEMSVHNPAASSFSRYAQENLGPLAGYITGWTYCFEILIV
                     AIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATI
                     IIMIVAGFGIIIWGIGNGGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEII
                     GITAGEAKDPEKSIPRAINSVPMRILVFYVGTLFVIMSIYPWNQVGTAGSPFVLTFQH
                     MGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAPKIFSKTSRRGIPWVT
                     VLVMTTALLFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVK
                     ALKFKVPGGVATTIGGLIFLLFIIGLIGYHPDTRISLYVGFAWIVVLLIGWMFKRRHD
                     RQLAENQ"
     misc_feature    482968..484332
                     /gene="proY"
                     /locus_tag="ECs_0452"
                     /note="putative proline-specific permease; Provisional;
                     Region: proY; PRK10580"
                     /db_xref="CDD:182566"
     gene            484497..486314
                     /gene="malZ"
                     /locus_tag="ECs_0453"
                     /db_xref="GeneID:914555"
     CDS             484497..486314
                     /gene="malZ"
                     /locus_tag="ECs_0453"
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin glucosidase"
                     /protein_id="NP_308480.3"
                     /db_xref="GeneID:914555"
                     /translation="MMLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDN
                     EEMSVPMHKQRSQPQPGVTAWRAAIDLSSGQPRRRYSFKLLWHDRQRWFTPQGFSRMP
                     PARLEQFAVDVPDIGPQWAADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILR
                     DWDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYR
                     HVDPQFGGDGALLRLRHNTQQLGMRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPES
                     PWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSIVRHWLKAPWNMDGW
                     RLDVVHMLGEAGGARNNLQHVAGITEAAKETQPEAYIVGEHFGDARQWLQADVEDAAM
                     NYRGFTFPLWGFLANTDISYDPQQIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDT
                     ARFKTLLGREVARLPLAVVWLFTWPGVPCIYYGDEVGLDGKNDPFCRKPFPWQVEKQD
                     MALFALYQRMIALRKKSQALRRGGCQVLYAEDNVVVFVRVLNQQRVLVAINRGEACEV
                     VLPASPFLNVVQWQRKEGHGQLTDGILALPAISATVWMN"
     misc_feature    484497..486287
                     /gene="malZ"
                     /locus_tag="ECs_0453"
                     /note="maltodextrin glucosidase; Provisional; Region:
                     PRK10785"
                     /db_xref="CDD:236759"
     gene            486502..487947
                     /locus_tag="ECs_0454"
                     /db_xref="GeneID:914556"
     CDS             486502..487947
                     /locus_tag="ECs_0454"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308481.1"
                     /db_xref="GeneID:914556"
                     /translation="MTISNSNLLKPFITGTELPPFKEDVFSKTEEQFKKSTYGKSLFI
                     SGNENLVNISAEKIDEIKNSKNFFSNIVNIIILLIKHPDKILPILHGCPVESIEVIKN
                     AKRTGQWSYEMTDKNGQSIEVSYIFTDTIDDKSDGKLCLKICNSCNQNDSSTHEYKID
                     HQQLKNHIRQLEEWALLEKFYDNNAYYSKRTKQLEKKIADAGFITRKVKAENFNVKEF
                     KDDIASMLCEQPPMRTHQISSSGYVSADKLHKLYKTNLEDAQRDLKTTPVDIDGVSLK
                     SITREKIAEEIAKKTAEIIAKQNAKSIEEKNIEKNKKQTNSEDNFVLKFSPEEINEML
                     LDYSDEEQKKLRPFFTSDHIYCLFDAFSQGLHNVARNGSPRYAGLLRQIASKSAILQD
                     FDQQLFWRTFTGGVLHRHISVKSEPEKTDVWRFSSQFDFPHINENGELSRTVLMFEGV
                     AESNFKDIANHSSECFSYRCYAAPLDANAKK"
     gene            complement(487968..488549)
                     /gene="acpH"
                     /locus_tag="ECs_0455"
                     /db_xref="GeneID:914557"
     CDS             complement(487968..488549)
                     /gene="acpH"
                     /locus_tag="ECs_0455"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="NP_308482.1"
                     /db_xref="GeneID:914557"
                     /translation="MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHM
                     HRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFV
                     CYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALR
                     DSWYDLDAHYAALETRFWQFYPRMMAQASRKAL"
     misc_feature    complement(487971..488549)
                     /gene="acpH"
                     /locus_tag="ECs_0455"
                     /note="ACP phosphodiesterase; Region: PRK10045"
                     /db_xref="CDD:182207"
     gene            488642..489712
                     /gene="queA"
                     /locus_tag="ECs_0456"
                     /db_xref="GeneID:914558"
     CDS             488642..489712
                     /gene="queA"
                     /locus_tag="ECs_0456"
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine:tRNA
                     ribosyltransferase-isomerase"
                     /protein_id="NP_308483.1"
                     /db_xref="GeneID:914558"
                     /translation="MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFT
                     DLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPK
                     PGAELLLGDDESINATMTARHGALFEVEFNDERSVLDILNSIGHMPLPPYIDRPDEDA
                     DRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVD
                     TIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPF
                     FDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRF
                     FSYGDAMFITYNPQAINERVGE"
     misc_feature    488642..489673
                     /gene="queA"
                     /locus_tag="ECs_0456"
                     /note="S-adenosylmethionine:tRNA
                     ribosyltransferase-isomerase; Provisional; Region: queA;
                     PRK00147"
                     /db_xref="CDD:234666"
     gene            489767..490894
                     /gene="tgt"
                     /locus_tag="ECs_0457"
                     /db_xref="GeneID:914559"
     CDS             489767..490894
                     /gene="tgt"
                     /locus_tag="ECs_0457"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-guanine transglycosylase"
                     /protein_id="NP_308484.1"
                     /db_xref="GeneID:914559"
                     /translation="MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPE
                     EVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIR
                     KITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSME
                     MSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVG
                     EPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGH
                     LFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHN
                     LRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD"
     misc_feature    489773..490876
                     /gene="tgt"
                     /locus_tag="ECs_0457"
                     /note="tRNA-guanine transglycosylase; Region: Q_tRNA_tgt;
                     TIGR00430"
                     /db_xref="CDD:129522"
     gene            490917..491249
                     /gene="yajC"
                     /locus_tag="ECs_0458"
                     /db_xref="GeneID:914560"
     CDS             490917..491249
                     /gene="yajC"
                     /locus_tag="ECs_0458"
                     /codon_start=1
                     /transl_table=11
                     /product="SecYEG protein translocase auxiliary subunit"
                     /protein_id="NP_308485.1"
                     /db_xref="GeneID:914560"
                     /translation="MSFFISDAVAATGAPAQGSPMSLILMLVVFGLIFYFMILRPQQK
                     RTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENGYIAIALNDTTEVVIKRDFVAAVL
                     PKGTMKAL"
     misc_feature    490923..491246
                     /gene="yajC"
                     /locus_tag="ECs_0458"
                     /note="preprotein translocase subunit YajC; Validated;
                     Region: yajC; PRK05585"
                     /db_xref="CDD:235518"
     gene            491310..493124
                     /gene="secD"
                     /locus_tag="ECs_0459"
                     /db_xref="GeneID:914561"
     CDS             491310..493124
                     /gene="secD"
                     /locus_tag="ECs_0459"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export membrane protein SecD"
                     /protein_id="NP_308486.2"
                     /db_xref="GeneID:914561"
                     /translation="MLIVVIVIGLLYALPNLFGEDPAVQITGARGVAASEQTLIQVQK
                     TLQEEKITAKSVALEEGAILARFDSTDTQLRAREALMGVMGDKYVVALNLAPATPRWL
                     AAIHAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLREKGIPYTTVRKE
                     NNYGLSITFRDAKARDEAIAYLSKRHPDLVISSQGSNQLRAVMSDARLSEAREYAVQQ
                     NINILRNRVNQLGVAEPVVQRQGADRIVVELPGIQDTARAKEILGATATLEFRLVNTN
                     VDQAAAASGRVPGDSEVKQTREGQPVVLYKRVILTGDHITDSTSSQDEYNQPQVNISL
                     DSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEVINIANIQSRLG
                     NSFRITGINNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNIEQGLEACLAGL
                     LVSILFMIIFYKKFGLIATSALIANLILIVGIMSLLPGATLSMPGIAGIVLTLAVAVD
                     ANVLINERIKEELSNGRTVQQAIDEGYRGAFSSIFDANITTLIKVIILYAVGTGAIKG
                     FAITTGIGVATSMFTAIVGTRAIVNLLYGGKRVKKLSI"
     misc_feature    491310..491582
                     /gene="secD"
                     /locus_tag="ECs_0459"
                     /note="SecD export protein N-terminal TM region; Region:
                     SecD-TM1; pfam13721"
                     /db_xref="CDD:433429"
     misc_feature    491586..493121
                     /gene="secD"
                     /locus_tag="ECs_0459"
                     /note="preprotein translocase subunit SecD; Reviewed;
                     Region: secD; PRK05812"
                     /db_xref="CDD:235615"
     gene            493135..494106
                     /gene="secF"
                     /locus_tag="ECs_0460"
                     /db_xref="GeneID:914562"
     CDS             493135..494106
                     /gene="secF"
                     /locus_tag="ECs_0460"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export membrane protein SecF"
                     /protein_id="NP_308487.1"
                     /db_xref="GeneID:914562"
                     /translation="MAQEYTVEQLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVR
                     GFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNFGSSHDIMVRMPPAE
                     GETGGQVLGSQVLKVINESTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVY
                     VGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVS
                     DRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLT
                     MLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPSILP"
     misc_feature    493156..494076
                     /gene="secF"
                     /locus_tag="ECs_0460"
                     /note="Preprotein translocase subunit SecF [Intracellular
                     trafficking, secretion, and vesicular transport]; Region:
                     SecF; COG0341"
                     /db_xref="CDD:223418"
     gene            494257..494499
                     /locus_tag="ECs_0461"
                     /db_xref="GeneID:914563"
     CDS             494257..494499
                     /locus_tag="ECs_0461"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_308488.1"
                     /db_xref="GeneID:914563"
                     /translation="MRKITSVSVGEQLDSFITRMVQSGRYGSASEVMRSALRLLEQQE
                     SRDEAVRNAVIEGLESGESSMTLRDIAAERKQKHRV"
     misc_feature    494266..494472
                     /locus_tag="ECs_0461"
                     /note="putative addiction module antidote protein, CC2985
                     family; Region: antidote_CC2985; TIGR02606"
                     /db_xref="CDD:274227"
     gene            494492..494773
                     /locus_tag="ECs_0462"
                     /db_xref="GeneID:914564"
     CDS             494492..494773
                     /locus_tag="ECs_0462"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization system protein"
                     /protein_id="NP_308489.1"
                     /db_xref="GeneID:914564"
                     /translation="MYKLSGKAVEDFRGIYDYTLGKFGDEQADRYTDSLGTFLDTLSQ
                     MPEIGQDYDAIPEVKKIAFRFHTVYYVIRVDDILIARILHQLMEPRRHW"
     misc_feature    494492..494770
                     /locus_tag="ECs_0462"
                     /note="Plasmid stabilization system protein ParE
                     [Mobilome: prophages, transposons]; Region: ParE; COG3668"
                     /db_xref="CDD:226194"
     gene            494861..495208
                     /gene="yajD"
                     /locus_tag="ECs_0463"
                     /db_xref="GeneID:914565"
     CDS             494861..495208
                     /gene="yajD"
                     /locus_tag="ECs_0463"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH nuclease family protein"
                     /protein_id="NP_308490.1"
                     /db_xref="GeneID:914565"
                     /translation="MAIIPKNYARLESGYREKALKIYPWVCGRCSREFVYSNLRELTV
                     HHIDHDHTNNPEDGSNWELLCLYCHDHEHSKYTEADQYGTTVIAGEDAQKDVGEAKYN
                     PFADLKAMMNKKK"
     misc_feature    494861..495199
                     /gene="yajD"
                     /locus_tag="ECs_0463"
                     /note="HNH nuclease family protein; Region: PRK11295"
                     /db_xref="CDD:236895"
     misc_feature    order(494987..494989,494993..495001,495005..495007,
                     495038..495043,495053..495058,495065..495067,
                     495077..495079)
                     /gene="yajD"
                     /locus_tag="ECs_0463"
                     /note="active site"
                     /db_xref="CDD:238038"
     gene            complement(495385..496269)
                     /gene="tsx"
                     /locus_tag="ECs_0464"
                     /db_xref="GeneID:914566"
     CDS             complement(495385..496269)
                     /gene="tsx"
                     /locus_tag="ECs_0464"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-specific channel-forming protein"
                     /protein_id="NP_308491.1"
                     /db_xref="GeneID:914566"
                     /translation="MKKTLLAAGAVLALSSSFTVNAAENDKPQYLSDWWHQSVNVVGS
                     YHTRFGPQIRNDTYLEYEAFAKKDWFDFYGYADAPVFFGGNSDAKGIWNHGSPLFMEI
                     EPRFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNKDGRQSTWYMGLGTDIDTGLPMS
                     LSMNVYAKYQWQNYGAANENEWDGYRFKIKYFVPITDLWGGQLSYIGFTNFDWGSDLG
                     DDSGNAINGIKTRTNNSIASSHILALNYDHWHYSVVARYWHDGGQWNDDAELNFGNGN
                     FNVRSTGWGGYLVVGYNF"
     misc_feature    complement(495388..496269)
                     /gene="tsx"
                     /locus_tag="ECs_0464"
                     /note="nucleoside-specific channel-forming protein Tsx;
                     Provisional; Region: PRK15106"
                     /db_xref="CDD:237911"
     gene            complement(496568..497107)
                     /gene="yajI"
                     /locus_tag="ECs_0465"
                     /db_xref="GeneID:914567"
     CDS             complement(496568..497107)
                     /gene="yajI"
                     /locus_tag="ECs_0465"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="NP_308492.2"
                     /db_xref="GeneID:914567"
                     /translation="MNINVFRLILLGSLFSLSACVQQSEVRQMKHSVSTLNQEMTQLN
                     QETVKITQQNRLNAKSSSGVYLLPGAKTPARLESQIGTLRMSLVNITPDTDGTTLTLR
                     IQGESNDPLPAFSGTVEYGQIQGTIDNFQEINVQNQLINAPASVLAPSDVDIPLQLKG
                     ISVDQLGFVRIHDIQPVMQ"
     misc_feature    complement(496571..497107)
                     /gene="yajI"
                     /locus_tag="ECs_0465"
                     /note="hypothetical protein; Provisional; Region:
                     PRK11530"
                     /db_xref="CDD:236923"
     gene            497258..497707
                     /gene="nrdR"
                     /locus_tag="ECs_0466"
                     /db_xref="GeneID:914568"
     CDS             497258..497707
                     /gene="nrdR"
                     /locus_tag="ECs_0466"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="NP_308493.1"
                     /db_xref="GeneID:914568"
                     /translation="MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVA
                     ELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGERE
                     VPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED"
     misc_feature    497258..497698
                     /gene="nrdR"
                     /locus_tag="ECs_0466"
                     /note="transcriptional regulator NrdR; Region: TIGR00244"
                     /db_xref="CDD:129347"
     gene            497711..498814
                     /gene="ribD"
                     /locus_tag="ECs_0467"
                     /db_xref="GeneID:914569"
     CDS             497711..498814
                     /gene="ribD"
                     /locus_tag="ECs_0467"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibD"
                     /protein_id="NP_308494.1"
                     /db_xref="GeneID:914569"
                     /translation="MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQ
                     RAGEPHAEVHALRMAGEKAKGATAYVTLEPCSHHGRTPPCCDALIAAGVARVVAAMQD
                     PNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGR
                     TAMASGESQWITSPQARRDVQRLRAQSHAILTSSATVLADDPALTVRWSELDVQTQAL
                     YPQHHLRQPVRIVIDSQNRVTPEHHIVQQPGETWFARTQEDSREWPETVRTLLIPEHK
                     GHLDLVVLMMQLGKQQINSIWVEAGPTLAGALLQAGLVDELIVYIAPKLLGSDARGLC
                     TLPGLEKLADAPQFKFKEIRHVGPDVCLHLVGA"
     misc_feature    497711..498811
                     /gene="ribD"
                     /locus_tag="ECs_0467"
                     /note="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD; Region: ribD; PRK10786"
                     /db_xref="CDD:182729"
     gene            498903..499373
                     /gene="ribE"
                     /locus_tag="ECs_0468"
                     /db_xref="GeneID:914570"
     CDS             498903..499373
                     /gene="ribE"
                     /locus_tag="ECs_0468"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase beta chain"
                     /protein_id="NP_308495.1"
                     /db_xref="GeneID:914570"
                     /translation="MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQV
                     KDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLA
                     HVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA"
     misc_feature    498903..499367
                     /gene="ribE"
                     /locus_tag="ECs_0468"
                     /note="6,7-dimethyl-8-ribityllumazine synthase;
                     Provisional; Region: ribH; PRK00061"
                     /db_xref="CDD:234606"
     misc_feature    order(498948..498950,498966..498968,499056..499067,
                     499074..499079,499083..499091,499095..499103,
                     499107..499109,499119..499121,499152..499154,
                     499158..499163,499167..499169,499173..499178,
                     499182..499190,499194..499202,499206..499220,
                     499227..499232,499242..499244,499248..499250,
                     499254..499256,499260..499262,499272..499274,
                     499284..499286,499308..499310,499317..499319,
                     499329..499331,499338..499343)
                     /gene="ribE"
                     /locus_tag="ECs_0468"
                     /note="homopentamer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:187742"
     misc_feature    order(498966..498971,499068..499079,499140..499157,
                     499161..499163,499167..499172,499239..499253,
                     499284..499286,499308..499310,499317..499319)
                     /gene="ribE"
                     /locus_tag="ECs_0468"
                     /note="active site"
                     /db_xref="CDD:187742"
     gene            499393..499812
                     /gene="nusB"
                     /locus_tag="ECs_0469"
                     /db_xref="GeneID:914571"
     CDS             499393..499812
                     /gene="nusB"
                     /locus_tag="ECs_0469"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination protein"
                     /protein_id="NP_308496.1"
                     /db_xref="GeneID:914571"
                     /translation="MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVD
                     VLYFRELLAGVATNTAYLDGLMKPYLSRLLEELGQVEKAVLRIALYELSKRSDVPYKV
                     AINEAIELAKSFGAEDSHKFVNGVLDKAAPVIRPNKK"
     misc_feature    499423..499809
                     /gene="nusB"
                     /locus_tag="ECs_0469"
                     /note="transcription antitermination factor NusB; Region:
                     nusB; PRK00202"
                     /db_xref="CDD:234686"
     gene            499890..500867
                     /gene="thiL"
                     /locus_tag="ECs_0470"
                     /db_xref="GeneID:914572"
     CDS             499890..500867
                     /gene="thiL"
                     /locus_tag="ECs_0470"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine monophosphate kinase"
                     /protein_id="NP_308497.1"
                     /db_xref="GeneID:914572"
                     /translation="MACGEFSLIARYFDRVRSSRLDVELGIGDDCALLNIPEKQTLAI
                     STDTLVAGNHFLPDIDPADLAYKALAVNLSDLAAMGADPAWLTLALTLPDVDEAWLES
                     FSDSLFDLLNYYDMQLIGGDTTRGPLSMTLGIHGFVPMGRALTRSGAKPGDWIYVTGT
                     PGDSAAGLAILQNRLQVADAKDADYLIKRHLRPSPRILQGQALRDLANSAIDLSDGLI
                     SDLGHIVKASDCGARIDLALLPFSDALSRHVVPEQALRWALSGGEDYELCFTVPELNR
                     GALDVALGHLGVPFTCIGQMTADIEGLCFIRDGEPVTLDWKGYDHFATP"
     misc_feature    499890..500855
                     /gene="thiL"
                     /locus_tag="ECs_0470"
                     /note="thiamine monophosphate kinase; Provisional; Region:
                     PRK05731"
                     /db_xref="CDD:235583"
     gene            500845..501360
                     /gene="pgpA"
                     /locus_tag="ECs_0471"
                     /db_xref="GeneID:914573"
     CDS             500845..501360
                     /gene="pgpA"
                     /locus_tag="ECs_0471"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="NP_308498.1"
                     /db_xref="GeneID:914573"
                     /translation="MTILPRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLA
                     AIPFWYLMTFLPWQLYSLVVMLGICIGVYLCHQTAKDMGVHDHGSIVWDEFIGMWITL
                     MALPTNDWQWVAAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILY
                     FIGHHWPLGIL"
     misc_feature    500866..501357
                     /gene="pgpA"
                     /locus_tag="ECs_0471"
                     /note="phosphatidylglycerophosphatase A; Provisional;
                     Region: PRK11068"
                     /db_xref="CDD:182942"
     misc_feature    order(500914..500916,500980..500982,501031..501033,
                     501040..501045,501052..501057,501103..501105,
                     501112..501120,501127..501132,501136..501141,
                     501148..501150,501181..501189,501193..501201,
                     501205..501210,501214..501219,501328..501330)
                     /gene="pgpA"
                     /locus_tag="ECs_0471"
                     /note="tetramer interfaces [polypeptide binding]; other
                     site"
                     /db_xref="CDD:133477"
     misc_feature    order(501112..501114,501121..501126,501274..501276,
                     501283..501288)
                     /gene="pgpA"
                     /locus_tag="ECs_0471"
                     /note="binuclear metal-binding site [ion binding]; other
                     site"
                     /db_xref="CDD:133477"
     gene            complement(501538..503109)
                     /gene="espY3"
                     /locus_tag="ECs_0472"
                     /db_xref="GeneID:914574"
     CDS             complement(501538..503109)
                     /gene="espY3"
                     /locus_tag="ECs_0472"
                     /codon_start=1
                     /transl_table=11
                     /product="T3SS effector-like protein EspY"
                     /protein_id="NP_308499.1"
                     /db_xref="GeneID:914574"
                     /translation="MMKTITKQPILFTDVPVADLRNSMKQDLNQNLIERLWNKIRDFF
                     LDSDKQKAFKSIHKYINTLSVLNYNSALTPDPNFNIDATSDLDSYLKLDFDRLSPKQK
                     QTTLCCFWNKIASSLPEPYNSTIKHNIIFYKDGENLMIRGTISIVNEVVKTYSLPIEK
                     DDNGYYDFSGLYLAHSNISGKDPNKDPDIDFGIDMGNCNCSNVNFEHTYFYGVKFTNA
                     NCTNANFNNCRFKKCDLTNMNCTGAILDNAMIYGKEKEPEMQYPEADQIIQRITYQKS
                     DGNETKGMILTNCSCVKTTFNWADLSESDCQNVDFSEANLSNTILPDIVRMKGTKLYR
                     TDLFNPILKTEAESTEEKDISPLAKIILDYIESDKNPESLNFEEKSTVIKIKQDIDNF
                     IFYNQHLKKIFNRAMNLQEKISRKKYNEFFKYIQAEAKQYFKDQYKLTKNDYLKKVPL
                     TAQLIAKYKMDDQLDQLLVTREIQDEIKSKIQDKIDELSKNLFNTMTETIENNFDDIF
                     RQQSENMSNYYEFVD"
     misc_feature    complement(502243..502998)
                     /gene="espY3"
                     /locus_tag="ECs_0472"
                     /note="Uncharacterized protein YjbI, contains pentapeptide
                     repeats [Function unknown]; Region: YjbI; COG1357"
                     /db_xref="CDD:224276"
     misc_feature    complement(502156..502254)
                     /gene="espY3"
                     /locus_tag="ECs_0472"
                     /note="Pentapeptide repeats (8 copies); Region:
                     Pentapeptide; pfam00805"
                     /db_xref="CDD:425877"
     gene            complement(503340..504314)
                     /gene="yajO"
                     /locus_tag="ECs_0473"
                     /db_xref="GeneID:914575"
     CDS             complement(503340..504314)
                     /gene="yajO"
                     /locus_tag="ECs_0473"
                     /codon_start=1
                     /transl_table=11
                     /product="2-carboxybenzaldehyde reductase"
                     /protein_id="NP_308500.1"
                     /db_xref="GeneID:914575"
                     /translation="MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPII
                     KRALEGGINFFDTANSYSDGSSEEIVGRALRDFSRREDVVVATKVFHRVGDLPEGLSR
                     AQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
                     ASQFAQALELQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGR
                     LTRPWGETTARLVSDEVGKNLYKESDENDAQIAERLTGVSEELGATRAQVALAWLLSK
                     PGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPVVGFK"
     misc_feature    complement(503379..504311)
                     /gene="yajO"
                     /locus_tag="ECs_0473"
                     /note="Escherichia coli YajO and similar proteins; Region:
                     AKR_EcYajO-like; cd19079"
                     /db_xref="CDD:381305"
     misc_feature    complement(order(503430..503435,503442..503444,
                     503451..503468,503517..503519,503664..503684,
                     503766..503768,503841..503846,503931..503936,
                     504051..504053,504132..504134,504147..504149,
                     504252..504260))
                     /gene="yajO"
                     /locus_tag="ECs_0473"
                     /note="putative active site [active]"
                     /db_xref="CDD:381305"
     misc_feature    complement(order(503934..503936,504051..504053,
                     504132..504134,504147..504149))
                     /gene="yajO"
                     /locus_tag="ECs_0473"
                     /note="catalytic tetrad [active]"
                     /db_xref="CDD:381305"
     gene            complement(504369..506231)
                     /gene="dxs"
                     /locus_tag="ECs_0474"
                     /db_xref="GeneID:914576"
     CDS             complement(504369..506231)
                     /gene="dxs"
                     /locus_tag="ECs_0474"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="NP_308501.1"
                     /db_xref="GeneID:914576"
                     /translation="MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVS
                     RSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKG
                     GLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMA
                     FEAMNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSG
                     VPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQ
                     FLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAA
                     KDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIY
                     STFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMT
                     PSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAI
                     LNFGTLMPEAAKVAESLNATLVDMRFVKPLDETLILEMAASHEALVTVEENAIMGGAG
                     SGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWLA"
     misc_feature    complement(504372..506201)
                     /gene="dxs"
                     /locus_tag="ECs_0474"
                     /note="1-deoxy-D-xylulose-5-phosphate synthase; Region:
                     dxs; TIGR00204"
                     /db_xref="CDD:129308"
     gene            complement(506256..507155)
                     /gene="ispA"
                     /locus_tag="ECs_0475"
                     /db_xref="GeneID:914577"
     CDS             complement(506256..507155)
                     /gene="ispA"
                     /locus_tag="ECs_0475"
                     /codon_start=1
                     /transl_table=11
                     /product="geranyltranstransferase"
                     /protein_id="NP_308502.1"
                     /db_xref="GeneID:914577"
                     /translation="MDFPQQLEACVKQANQALSRFIAPLPFQNTPVVETMQYGALLGG
                     KRLRPFLVYATGHMFGVSTNTLDAPAAAVECIHAYSLIHDDLPAMDDDDLRRGLPTCH
                     VKFGEANAILAGDALQTLAFSILSDADMPEVSDRDRISMISELASASGIAGMCGGQAL
                     DLDAEGKHVPLDALERIHRHKTGALIRAAVRLGALSAGDKGRRALPVLDKYAESIGLA
                     FQVQDDILDVVGDTATLGKRQGADQQLGKSTYPALLGLEQARKKAQDLIDDARQSLKQ
                     LAEQSIDTSALEALADYIIQRNK"
     misc_feature    complement(506259..507155)
                     /gene="ispA"
                     /locus_tag="ECs_0475"
                     /note="(2E,6E)-farnesyl diphosphate synthase; Region:
                     PRK10581"
                     /db_xref="CDD:182567"
     misc_feature    complement(order(506415..506417,506430..506432,
                     506445..506447,506475..506477,506484..506489,
                     506601..506603,506610..506615,506673..506675,
                     506682..506684,506868..506873,506907..506909,
                     506913..506921,506928..506930))
                     /gene="ispA"
                     /locus_tag="ECs_0475"
                     /note="substrate binding pocket [chemical binding]; other
                     site"
                     /db_xref="CDD:173833"
     misc_feature    complement(order(506409..506423,506430..506447,
                     506463..506468,506838..506876,506904..506906))
                     /gene="ispA"
                     /locus_tag="ECs_0475"
                     /note="active site lid residues [active]"
                     /db_xref="CDD:173833"
     misc_feature    complement(order(506415..506417,506430..506432,
                     506445..506447,506475..506477,506484..506489))
                     /gene="ispA"
                     /locus_tag="ECs_0475"
                     /note="aspartate-rich region 2; other site"
                     /db_xref="CDD:173833"
     gene            complement(507155..507397)
                     /gene="xseB"
                     /locus_tag="ECs_0476"
                     /db_xref="GeneID:914578"
     CDS             complement(507155..507397)
                     /gene="xseB"
                     /locus_tag="ECs_0476"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease VII small subunit"
                     /protein_id="NP_308503.1"
                     /db_xref="GeneID:914578"
                     /translation="MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQ
                     LARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE"
     misc_feature    complement(507164..507397)
                     /gene="xseB"
                     /locus_tag="ECs_0476"
                     /note="exodeoxyribonuclease VII small subunit;
                     Provisional; Region: PRK00977"
                     /db_xref="CDD:179195"
     gene            507603..509051
                     /gene="thiI"
                     /locus_tag="ECs_0477"
                     /db_xref="GeneID:914579"
     CDS             507603..509051
                     /gene="thiI"
                     /locus_tag="ECs_0477"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA s(4)U8 sulfurtransferase"
                     /protein_id="NP_308504.1"
                     /db_xref="GeneID:914579"
                     /translation="MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVV
                     RHWDNIEVRAKDENQRLTIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDQL
                     DGKTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPDVTVHLEVEDDRLL
                     LIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEI
                     GVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVA
                     ERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTE
                     DFARTMPEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEANNVDIREIAQQTG
                     QEVVEVETVNDFGPNDVILDIRSVDEQEDKPLKVEGIDVVSLPFYKLSTKFGDLDQNR
                     TWLLWCERGVMSRLQALYLREQGFKNVKVYRP"
     misc_feature    507612..508730
                     /gene="thiI"
                     /locus_tag="ECs_0477"
                     /note="tRNA sulfurtransferase ThiI; Region: TIGR00342"
                     /db_xref="CDD:273025"
     misc_feature    508746..509048
                     /gene="thiI"
                     /locus_tag="ECs_0477"
                     /note="thiazole biosynthesis domain; Region:
                     ThiI_C_thiazole; TIGR04271"
                     /db_xref="CDD:275094"
     misc_feature    508968..508970
                     /gene="thiI"
                     /locus_tag="ECs_0477"
                     /note="active site residue [active]"
                     /db_xref="CDD:238089"
     gene            complement(509105..509695)
                     /gene="yajL"
                     /locus_tag="ECs_0478"
                     /db_xref="GeneID:914580"
     CDS             complement(509105..509695)
                     /gene="yajL"
                     /locus_tag="ECs_0478"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative stress resistance chaperone"
                     /protein_id="NP_308505.2"
                     /db_xref="GeneID:914580"
                     /translation="MSASALVCLAPGSEETEAVTTIDLLIRGGIKVTTASVASDGNLA
                     ITCSRGVKLLADAPLVEVADGEYDVIVLPGGIKGAECFRDSTLLVETVKQFHRSGRIV
                     AAICAAPATVLVPHDIFPIGNMTGFPTLKDKIPAEQWQDKRVVWDARVKLLTSQGPGT
                     AIDFGLKIIDLLVGREKAHEVASQLVMAAGIYNYYE"
     misc_feature    complement(509108..509695)
                     /gene="yajL"
                     /locus_tag="ECs_0478"
                     /note="protein deglycase YajL; Region: PRK11574"
                     /db_xref="CDD:183210"
     misc_feature    complement(509378..509380)
                     /gene="yajL"
                     /locus_tag="ECs_0478"
                     /note="conserved cys residue [active]"
                     /db_xref="CDD:153229"
     gene            complement(509658..510569)
                     /gene="panE"
                     /locus_tag="ECs_0479"
                     /db_xref="GeneID:914581"
     CDS             complement(509658..510569)
                     /gene="panE"
                     /locus_tag="ECs_0479"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate reductase"
                     /protein_id="NP_308506.1"
                     /db_xref="GeneID:914581"
                     /translation="MKITVLGCGALGQLWLTALCKQGHEVQGWLRVPQPYCSVNLVET
                     DGSIFNESLTANDPDFLATSDLLLVTLKAWQVSDAVKSLASTLPVTTPILLIHNGMGT
                     IEELQNIQQPLLMGTTTHAACRDGNVIIHVANGITHIGPARQQDGDYSYLADILQTVL
                     PDVAWHNNIRAELWRKLAVNCVINPLTAIWNCPNGELRHHPQEIMQICEEVAAVIERE
                     GHHTSAEDLRDYVMQVIDATAENISSMLQDIRTLRHTEIDYINGFLLRRARAHGIAVP
                     ENTRLFEMVKRKESEYERIGTGLPRPW"
     misc_feature    complement(509685..510569)
                     /gene="panE"
                     /locus_tag="ECs_0479"
                     /note="2-dehydropantoate 2-reductase; Reviewed; Region:
                     PRK06522"
                     /db_xref="CDD:235821"
     gene            510737..511228
                     /gene="yajQ"
                     /locus_tag="ECs_0480"
                     /db_xref="GeneID:914582"
     CDS             510737..511228
                     /gene="yajQ"
                     /locus_tag="ECs_0480"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide binding protein"
                     /protein_id="NP_308507.2"
                     /db_xref="GeneID:914582"
                     /translation="MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDA
                     SKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGI
                     ESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKN
                     FRD"
     misc_feature    510737..511225
                     /gene="yajQ"
                     /locus_tag="ECs_0480"
                     /note="putative nucleotide-binding protein; Reviewed;
                     Region: PRK05412"
                     /db_xref="CDD:180061"
     gene            complement(511356..512720)
                     /gene="yajR"
                     /locus_tag="ECs_0481"
                     /db_xref="GeneID:914583"
     CDS             complement(511356..512720)
                     /gene="yajR"
                     /locus_tag="ECs_0481"
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="NP_308508.2"
                     /db_xref="GeneID:914583"
                     /translation="MNDYKMTPGERRATWGLGTVFSLRMLGMFMVLPVLTTYGMALQG
                     ASEALIGIAIGIYGLTQAVFQIPFGLLSDRIGRKPLIVGGLAVFAAGSVIAALSDSIW
                     GIILGRALQGSGAIAAAVMALLSDLTREQNRTKAMAFIGVSFGITFAIAMVLGPIITH
                     KLGLHALFWMIAILATTGIALTIWVVPNSSTHVLNRESGMVKGSFSKVLAEPRLLKLN
                     FGIMCLHILLMSTFVALPGQLADAGFPAAEHWKVYLATMLIAFGSVVPFIIYAEVKRK
                     MKQVFVFCVGLIVVAEIVLRNAQTQFWQLVVGVQLFFVAFNLMEALLPSLISKESPAG
                     YKGTAMGVYSTSQFLGVAIGGSLGGWIDGMFDGQGVFLAGAMLAAVWLAVASTMKEPP
                     YVSSLRIEIPANIAANEALKVRLLETEGIKEVLIAEEEHSAYVKIDSKVTNRFDVEQA
                     IRQA"
     misc_feature    complement(511554..512672)
                     /gene="yajR"
                     /locus_tag="ECs_0481"
                     /note="Escherichia coli inner membrane transport protein
                     YajR and similar multidrug-efflux transporters of the
                     Major Facilitator Superfamily; Region: MFS_YajR_like;
                     cd17472"
                     /db_xref="CDD:341025"
     misc_feature    complement(order(511668..511670,511677..511682,
                     511689..511694,511701..511703,511770..511772,
                     511782..511784,511794..511799,511929..511931,
                     511941..511943,512022..512024,512031..512039,
                     512046..512051,512058..512060,512265..512267,
                     512274..512279,512286..512288,512352..512354,
                     512361..512369,512373..512378,512526..512528,
                     512625..512627,512634..512639,512646..512651))
                     /gene="yajR"
                     /locus_tag="ECs_0481"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]; other site"
                     /db_xref="CDD:341025"
     gene            complement(512869..513759)
                     /gene="cyoE"
                     /locus_tag="ECs_0482"
                     /db_xref="GeneID:914584"
     CDS             complement(512869..513759)
                     /gene="cyoE"
                     /locus_tag="ECs_0482"
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX farnesyltransferase"
                     /protein_id="NP_308509.1"
                     /db_xref="GeneID:914584"
                     /translation="MMFKQYLQVTKPGIIFGNLISVIGGFLLASKGSIDYPLFIYTLV
                     GVSLVVASGCVFNNYIDRDIDRKMERTKNRVLVKGLISPAVSLVYATLLGIAGFMLLW
                     FGANPLACWLGVMGFVVYVGVYSLYMKRHSVYGTLIGSLSGAAPPVIGYCAVTGEFDS
                     GAAILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGISVAKNHITLYIIAFAV
                     ATLMLSLGGYAGYKYLVVAAAVSVWWLGMALRGYKVADDRIWARKLFGFSIIAITALS
                     VMMSVDFMVPDSHTLLAAVW"
     misc_feature    complement(512902..513759)
                     /gene="cyoE"
                     /locus_tag="ECs_0482"
                     /note="protoheme IX farnesyltransferase; Provisional;
                     Region: PRK04375"
                     /db_xref="CDD:235293"
     gene            complement(513771..514100)
                     /gene="cyoD"
                     /locus_tag="ECs_0483"
                     /db_xref="GeneID:914585"
     CDS             complement(513771..514100)
                     /gene="cyoD"
                     /locus_tag="ECs_0483"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit IV"
                     /protein_id="NP_308510.1"
                     /db_xref="GeneID:914585"
                     /translation="MSHSTDHSGASHGSVKTYMTGFILSIILTVIPFWMVMTGAASPA
                     VILGTILAMAVVQVLVHLVCFLHMNTKSDEGWNMTAFVFTVLIIAILVVGSIWIMWNL
                     NYNMMMH"
     misc_feature    complement(513774..514100)
                     /gene="cyoD"
                     /locus_tag="ECs_0483"
                     /note="cytochrome o ubiquinol oxidase subunit IV;
                     Provisional; Region: PRK10582"
                     /db_xref="CDD:182568"
     gene            complement(514100..514714)
                     /gene="cyoC"
                     /locus_tag="ECs_0484"
                     /db_xref="GeneID:914586"
     CDS             complement(514100..514714)
                     /gene="cyoC"
                     /locus_tag="ECs_0484"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit III"
                     /protein_id="NP_308511.1"
                     /db_xref="GeneID:914586"
                     /translation="MATDTLTHATVHAHEHGHHDAGGTKIFGFWIYLMSDCILFSILF
                     ATYAVLVNGTAGGPTGKDIFELPFVLVETFLLLFSSITYGMAAIAMYKNNKSQVISWL
                     ALTWLFGAGFIGMEIYEFHHLIVNGMGPDRSGFLSAFFALVGTHGLHVTSGLIWMAVL
                     MVQIARRGLTSTNRTRIMCLSLFWHFLDVVWICVFTVVYLMGAM"
     misc_feature    complement(514103..514714)
                     /gene="cyoC"
                     /locus_tag="ECs_0484"
                     /note="cytochrome o ubiquinol oxidase subunit III;
                     Provisional; Region: PRK10663"
                     /db_xref="CDD:182628"
     misc_feature    complement(order(514577..514579,514586..514591,
                     514598..514603,514622..514624,514631..514633,
                     514643..514648))
                     /gene="cyoC"
                     /locus_tag="ECs_0484"
                     /note="Subunit I/III interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239214"
     misc_feature    complement(order(514160..514162,514181..514183,
                     514466..514471,514481..514483,514490..514492,
                     514601..514603,514625..514627))
                     /gene="cyoC"
                     /locus_tag="ECs_0484"
                     /note="Subunit III/IV interface [polypeptide binding];
                     other site"
                     /db_xref="CDD:239214"
     gene            complement(514704..516695)
                     /gene="cyoB"
                     /locus_tag="ECs_0485"
                     /db_xref="GeneID:914587"
     CDS             complement(514704..516695)
                     /gene="cyoB"
                     /locus_tag="ECs_0485"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit I"
                     /protein_id="NP_308512.1"
                     /db_xref="GeneID:914587"
                     /translation="MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYL
                     WKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQI
                     FTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSL
                     GVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAP
                     GMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYI
                     NLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHH
                     FFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFS
                     VGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNE
                     TWGKRAFWFWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALG
                     ILCLVIQMYVSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHERDAFWE
                     MKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIIT
                     WIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLKNGN"
     misc_feature    complement(514707..516695)
                     /gene="cyoB"
                     /locus_tag="ECs_0485"
                     /note="cytochrome o ubiquinol oxidase subunit I;
                     Provisional; Region: PRK15017"
                     /db_xref="CDD:184978"
     misc_feature    complement(order(516063..516065,516075..516077,
                     516093..516098,516261..516263,516270..516272,
                     516291..516293,516321..516323,516513..516515))
                     /gene="cyoB"
                     /locus_tag="ECs_0485"
                     /note="D-pathway [active]"
                     /db_xref="CDD:238832"
     misc_feature    complement(order(516387..516395,516402..516404,
                     516459..516464,516471..516473,516483..516485))
                     /gene="cyoB"
                     /locus_tag="ECs_0485"
                     /note="Putative ubiquinol binding site [chemical binding];
                     other site"
                     /db_xref="CDD:238832"
     misc_feature    complement(order(515181..515183,515295..515297,
                     515421..515423,515433..515435,516378..516380))
                     /gene="cyoB"
                     /locus_tag="ECs_0485"
                     /note="Low-spin heme (heme b) binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:238832"
     misc_feature    complement(order(515253..515255,515460..515465,
                     515475..515477,515865..515870,515883..515885))
                     /gene="cyoB"
                     /locus_tag="ECs_0485"
                     /note="Putative water exit pathway; other site"
                     /db_xref="CDD:238832"
     misc_feature    complement(order(515439..515441,515694..515699,
                     515844..515846))
                     /gene="cyoB"
                     /locus_tag="ECs_0485"
                     /note="Binuclear center (heme o3/CuB) [ion binding]; other
                     site"
                     /db_xref="CDD:238832"
     misc_feature    complement(order(515610..515612,515619..515621,
                     515694..515699,515799..515801,515832..515834,
                     515844..515846))
                     /gene="cyoB"
                     /locus_tag="ECs_0485"
                     /note="K-pathway [active]"
                     /db_xref="CDD:238832"
     misc_feature    complement(order(515250..515255,515460..515465,
                     515694..515696))
                     /gene="cyoB"
                     /locus_tag="ECs_0485"
                     /note="Putative proton exit pathway; other site"
                     /db_xref="CDD:238832"
     gene            complement(516717..517664)
                     /gene="cyoA"
                     /locus_tag="ECs_0486"
                     /db_xref="GeneID:914588"
     CDS             complement(516717..517664)
                     /gene="cyoA"
                     /locus_tag="ECs_0486"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit II"
                     /protein_id="NP_308513.1"
                     /db_xref="GeneID:914588"
                     /translation="MRLRKYNKSLGWLSLFAGTVLLSGCNSALLDPKGQIGLEQRSLI
                     LTAFGLMLIVVIPAILMAVGFAWKYRASNKDAKYSPNWSHSNKVEAVVWTVPILIIIF
                     LAVLTWKTTHALEPSKPLAHDEKPITIEVVSMDWKWFFIYPEQGFATVNEIAFPANTP
                     VYFKVTSNSVMNSFFIPRLGSQIYAMAGMQTRLHLIANEPGTYDGISASYSGPGFSGM
                     KFKAIATPDRAAFDQWVAKAKQSPNSMSDMAAFEKLAAPSEYNQVEYFSNVKPNLFAD
                     VINKFMAHGKSMDMTQPEGEHSAHEGMEGMDMSHAESAH"
     misc_feature    complement(516720..517664)
                     /gene="cyoA"
                     /locus_tag="ECs_0486"
                     /note="cytochrome o ubiquinol oxidase subunit II;
                     Provisional; Region: PRK10525"
                     /db_xref="CDD:182518"
     gene            complement(518124..519599)
                     /gene="ampG"
                     /locus_tag="ECs_0487"
                     /db_xref="GeneID:914589"
     CDS             complement(518124..519599)
                     /gene="ampG"
                     /locus_tag="ECs_0487"
                     /codon_start=1
                     /transl_table=11
                     /product="muropeptide transporter"
                     /protein_id="NP_308514.1"
                     /db_xref="GeneID:914589"
                     /translation="MSSQYLRIFQQPRSAILLILGFASGLPLALTSGTLQAWMTVENI
                     DLKTIGFFSLVGQAYVFKFLWSPLMDRYTPPFFGRRRGWLLATQILLLVAIAAMGFLE
                     PGTQLRWMAALAVVIAFCSASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSG
                     GLALWLADKWLGWQGMYWLMAALLIPCIIATLLAPEPTDTIPVPKTLEQAVVAPLRDF
                     FGRNNAWLILLLIVLYKLGDAFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGA
                     LYGGILMQRLSLFRALLIFGILQGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGT
                     SAFVALLMTLCNKSFSATQFALLSALSAVGRVYVGPVAGWFVEAHGWSTFYLFSVAAA
                     VPGLILLLVCRQTLEYTRVNDNFISRTAYPAGYAFAMWTLAAGVSLLAVWLLLLTMDA
                     LDLTHFSFLPALLEVGVLVALSGVVLGGLLDYLALRKTHLT"
     misc_feature    complement(518130..519599)
                     /gene="ampG"
                     /locus_tag="ECs_0487"
                     /note="muropeptide MFS transporter AmpG; Region: ampG;
                     PRK11010"
                     /db_xref="CDD:182898"
     misc_feature    complement(order(518493..518495,518502..518507,
                     518514..518519,518526..518528,518574..518576,
                     518586..518588,518598..518603,518772..518774,
                     518784..518786,518871..518873,518880..518888,
                     518895..518900,518907..518909,519144..519146,
                     519153..519158,519165..519167,519213..519215,
                     519222..519230,519234..519239,519414..519416,
                     519504..519506,519513..519518,519525..519530))
                     /gene="ampG"
                     /locus_tag="ECs_0487"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]; other site"
                     /db_xref="CDD:341039"
     gene            complement(519643..520221)
                     /gene="yajG"
                     /locus_tag="ECs_0488"
                     /db_xref="GeneID:914590"
     CDS             complement(519643..520221)
                     /gene="yajG"
                     /locus_tag="ECs_0488"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="NP_308515.2"
                     /db_xref="GeneID:914590"
                     /translation="MFKKILFPLVALFMLAGCARPPTTIEVSPTITLPQQDPSLMGVT
                     VSINGADQRTDQALAKVTRDNQIVTLTASRDLRFLLQEVLEKQMTARGYMVGPNGPVN
                     LQIIVSQLYADVSQGNVRYNIATKADIAIIATAQNGNKMTKNYRASYNVEGAFQASNK
                     NIADAVNSVLTDTIADMSQDTSIHEFIKQNAR"
     misc_feature    complement(519646..520221)
                     /gene="yajG"
                     /locus_tag="ECs_0488"
                     /note="hypothetical protein; Provisional; Region:
                     PRK11627"
                     /db_xref="CDD:183242"
     gene            520529..520843
                     /gene="bolA"
                     /locus_tag="ECs_0489"
                     /db_xref="GeneID:914591"
     CDS             520529..520843
                     /gene="bolA"
                     /locus_tag="ECs_0489"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator BolA"
                     /protein_id="NP_308516.3"
                     /db_xref="GeneID:914591"
                     /translation="MIRERIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLVS
                     DRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYTIKEWEGLQDTVFASPPCRGAGS
                     IA"
     misc_feature    520529..520840
                     /gene="bolA"
                     /locus_tag="ECs_0489"
                     /note="transcriptional regulator BolA; Provisional;
                     Region: PRK11628"
                     /db_xref="CDD:183243"
     gene            521187..522485
                     /gene="tig"
                     /locus_tag="ECs_0490"
                     /db_xref="GeneID:914592"
     CDS             521187..522485
                     /gene="tig"
                     /locus_tag="ECs_0490"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis/trans isomerase"
                     /protein_id="NP_308517.1"
                     /db_xref="GeneID:914592"
                     /translation="MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGF
                     RKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGED
                     FTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEA
                     EDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFP
                     EEYHAENLKGKAAKFAINLKKVEERELPELTAEFIKRFGVEDGSVEGLRAEVRKNMER
                     ELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPR
                     ELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNK
                     ELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMNQQA"
     misc_feature    521187..522482
                     /gene="tig"
                     /locus_tag="ECs_0490"
                     /note="FKBP-type peptidyl-prolyl cis-trans isomerase
                     (trigger factor) [Posttranslational modification, protein
                     turnover, chaperones]; Region: Tig; COG0544"
                     /db_xref="CDD:223618"
     gene            522730..523353
                     /gene="clpP"
                     /locus_tag="ECs_0491"
                     /db_xref="GeneID:914593"
     CDS             522730..523353
                     /gene="clpP"
                     /locus_tag="ECs_0491"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="NP_308518.1"
                     /db_xref="GeneID:914593"
                     /translation="MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIF
                     LTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVS
                     TICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
                     GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN"
     misc_feature    522763..523350
                     /gene="clpP"
                     /locus_tag="ECs_0491"
                     /note="ATP-dependent Clp protease proteolytic subunit;
                     Reviewed; Region: clpP; PRK00277"
                     /db_xref="CDD:178955"
     misc_feature    order(522859..522861,522865..522867,522892..522897,
                     522904..522909,522916..522918,522961..522963,
                     522982..522984,522994..522996,523003..523005,
                     523012..523017,523027..523029,523051..523053,
                     523117..523119,523123..523125,523141..523152,
                     523192..523194,523201..523203,523207..523209,
                     523213..523215,523282..523284,523288..523290)
                     /gene="clpP"
                     /locus_tag="ECs_0491"
                     /note="oligomer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:132928"
     misc_feature    order(523060..523062,523135..523137,523282..523284)
                     /gene="clpP"
                     /locus_tag="ECs_0491"
                     /note="active site residues [active]"
                     /db_xref="CDD:132928"
     gene            523479..524753
                     /gene="clpX"
                     /locus_tag="ECs_0492"
                     /db_xref="GeneID:914594"
     CDS             523479..524753
                     /gene="clpX"
                     /locus_tag="ECs_0492"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATP-binding subunit ClpX"
                     /protein_id="NP_308519.1"
                     /db_xref="GeneID:914594"
                     /translation="MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLC
                     NDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNG
                     DTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
                     IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGT
                     VAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVISHRVETGSGIGFGATVKA
                     KSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALT
                     KQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMED
                     VEKVVIDESVIDGQSKPLLIYGKPEAQQASGE"
     misc_feature    523488..524729
                     /gene="clpX"
                     /locus_tag="ECs_0492"
                     /note="ATP-dependent Clp protease ATP-binding subunit
                     ClpX; Region: clpX; PRK05342"
                     /db_xref="CDD:235422"
     gene            524941..527295
                     /gene="lon"
                     /locus_tag="ECs_0493"
                     /db_xref="GeneID:914595"
     CDS             524941..527295
                     /gene="lon"
                     /locus_tag="ECs_0493"
                     /codon_start=1
                     /transl_table=11
                     /product="lon protease"
                     /protein_id="NP_308520.1"
                     /db_xref="GeneID:914595"
                     /translation="MNPERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSIRCLEAAM
                     DHDKKIMLVAQKEASTDEPGVNDLFTVGTVASILQMLKLPDGTVKVLVEGLQRARISA
                     LSDNGEHFSAKAEYLESPTIDEREQEVLVRTAISQFEGYIKLNKKIPPEVLTSLNSID
                     DPARLADTIAAHMPLKLADKQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVK
                     KQMEKSQREYYLNEQMKAIQKELGEMDDAPDENEALKRKIDAAKMPKEAKEKAEAELQ
                     KLKMMSPMSAEATVVRGYIDWMVQVPWNARSKVKKDLRQAQEILNTDHYGLERVKDRI
                     LEYLAVQSRVNKIKGPILCLVGPPGVGKTSLGQSIAKATGRKYVRMALGGVRDEAEIR
                     GHRRTYIGSMPGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNV
                     AFSDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKRHLLP
                     KQIERNALKKGELTVDDSAIIGIIRYYTREAGVRGLEREISKLCRKAVKQLLLDKSLK
                     HIEINGDNLHDYLGVQRFDYGRADNENRVGQVTGLAWTEVGGDLLTIETACVPGKGKL
                     TYTGSLGEVMQESIQAALTVVRARAEKLGINPDFYEKRDIHVHVPEGATPKDGPSAGI
                     AMCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLKEKLLAAHRGGIKTVLIPFEN
                     KRDLEEIPDNVIADLDIHPVKRIEEVLTLALQNEPSGMQVVTAK"
     misc_feature    524941..527292
                     /gene="lon"
                     /locus_tag="ECs_0493"
                     /note="DNA-binding ATP-dependent protease La; Provisional;
                     Region: PRK10787"
                     /db_xref="CDD:182730"
     gene            527504..527776
                     /gene="hupB"
                     /locus_tag="ECs_0494"
                     /db_xref="GeneID:914596"
     CDS             527504..527776
                     /gene="hupB"
                     /locus_tag="ECs_0494"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator HU subunit beta"
                     /protein_id="NP_308521.1"
                     /db_xref="GeneID:914596"
                     /translation="MNKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVAL
                     VGFGTFAVKERAARTGRNPQTGKEITIAAAKVPSFRAGKALKDAVN"
     misc_feature    527504..527773
                     /gene="hupB"
                     /locus_tag="ECs_0494"
                     /note="DNA-binding protein HU-beta; Region: PRK10664"
                     /db_xref="CDD:170612"
     misc_feature    order(527519..527521,527528..527533,527540..527542,
                     527567..527578,527582..527590,527594..527602,
                     527606..527611,527621..527635,527642..527644,
                     527726..527734,527738..527740,527744..527746,
                     527756..527761)
                     /gene="hupB"
                     /locus_tag="ECs_0494"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:259853"
     misc_feature    order(527660..527662,527666..527671,527675..527677,
                     527681..527692,527705..527710,527714..527716)
                     /gene="hupB"
                     /locus_tag="ECs_0494"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:259853"
     gene            527968..529839
                     /gene="ppiD"
                     /locus_tag="ECs_0495"
                     /db_xref="GeneID:914597"
     CDS             527968..529839
                     /gene="ppiD"
                     /locus_tag="ECs_0495"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase D"
                     /protein_id="NP_308522.1"
                     /db_xref="GeneID:914597"
                     /translation="MMDSLRTAANSLVLKIIFGIIIVSFILTGVSGYLIGGGNNYAAK
                     VNDQEISRGQFENAFNSERNRMQQQLGDQYSELAANEGYMKTLRQQVLNRLIDEALLD
                     QYARELKLGISDEQVKQAIFATPAFQVDGKFDNSRYNGILNQMGMTADQYAQALRNQL
                     TTQQLINGVAGTDFMLKGETDELAALVAQQRVVREATIDVNALAAKQPVTEQEIASYY
                     EQNKNNFMTPEQFRVSYIKLDAATMQQPVSDADLQSYYDQHQDQFTQPQRTRYSIIQT
                     KTEDEAKAVLDELNKGGDFAALAKEKSADIISARNGGDMGWLEDATIPDELKNAGLKE
                     KGQLSGVIKSSVGFLIVRLDDIQPAKVKSLDEVRDDVAAKVKHEKALDAYYALQQKVS
                     DAASNDTESLAGAEQAAGVKATQTGWFSKENLPEELNFKPVADAIFNGGLVGENGAPG
                     INSDIITVDGDRAFVLRISEHKPEAVKPLADVQEQVKALVQHNKAEQQAKVDAEKLLV
                     DLKAGKGAEAMQAAGLKFGEPKTLSRSGRDPISQAAFALPLPAKDKPSYGMATDMQGN
                     VVLLALDEVKQGSMPEDQKKAMVQGITQNNAQIVFEALMSNLRKEAKIKIGDALEQQ"
     misc_feature    527968..529824
                     /gene="ppiD"
                     /locus_tag="ECs_0495"
                     /note="periplasmic folding chaperone; Provisional; Region:
                     PRK10788"
                     /db_xref="CDD:182731"
     gene            529990..530361
                     /gene="ybaV"
                     /locus_tag="ECs_0496"
                     /db_xref="GeneID:914598"
     CDS             529990..530361
                     /gene="ybaV"
                     /locus_tag="ECs_0496"
                     /codon_start=1
                     /transl_table=11
                     /product="competence-suppressing periplasmic
                     helix-hairpin-helix DNA-binding protein"
                     /protein_id="NP_308523.1"
                     /db_xref="GeneID:914598"
                     /translation="MKHGIKALLITLSLACAGMSHSALAAASVAKPTAVETKAEAPAA
                     QNKAAVPAKASDEEGSRVSINNASAEELARAMNGVGLKKAQAIVSYREEYGPFKTVED
                     LKQVPGMGNSLVERNLAVLTL"
     misc_feature    530152..530358
                     /gene="ybaV"
                     /locus_tag="ECs_0496"
                     /note="competence protein ComEA helix-hairpin-helix repeat
                     region; Region: TIGR00426"
                     /db_xref="CDD:129520"
     gene            530467..530865
                     /gene="fadM"
                     /locus_tag="ECs_0497"
                     /db_xref="GeneID:914599"
     CDS             530467..530865
                     /gene="fadM"
                     /locus_tag="ECs_0497"
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain acyl-CoA thioesterase III"
                     /protein_id="NP_308524.1"
                     /db_xref="GeneID:914599"
                     /translation="MQTQIKVRGYHLDVYQHVNNARYLEFLEEARWDGLENSDSFHWM
                     TAHNIAFVVVNININYRRPAVLSDLLTITSQLQQLNGKSGILSQVITLEPEGQVVADA
                     LITFVCIDLKTQKALALEGELREKLEQMVK"
     misc_feature    530479..530826
                     /gene="fadM"
                     /locus_tag="ECs_0497"
                     /note="acyl-CoA thioester hydrolase, YbgC/YbaW family;
                     Region: TIGR00051"
                     /db_xref="CDD:129161"
     misc_feature    order(530548..530550,530617..530619,530623..530625,
                     530704..530715)
                     /gene="fadM"
                     /locus_tag="ECs_0497"
                     /note="active site"
                     /db_xref="CDD:238329"
     gene            complement(530917..531612)
                     /gene="queC"
                     /locus_tag="ECs_0498"
                     /db_xref="GeneID:914600"
     CDS             complement(530917..531612)
                     /gene="queC"
                     /locus_tag="ECs_0498"
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase"
                     /protein_id="NP_308525.1"
                     /db_xref="GeneID:914600"
                     /translation="MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEID
                     VARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNIL
                     FLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKVLNHAVSLGMAKDIRFETPL
                     MWIDKAETWALADYYGKLDLVRNETLTCYNGIKGDGCGHCAACNLRANGLNHYLADKP
                     TVMAAMKQKTGLK"
     misc_feature    complement(530920..531612)
                     /gene="queC"
                     /locus_tag="ECs_0498"
                     /note="queuosine biosynthesis protein QueC; Provisional;
                     Region: PRK11106"
                     /db_xref="CDD:182967"
     misc_feature    complement(order(531499..531501,531505..531507,
                     531571..531582,531586..531594))
                     /gene="queC"
                     /locus_tag="ECs_0498"
                     /note="Ligand Binding Site [chemical binding]; other site"
                     /db_xref="CDD:238953"
     gene            complement(531677..533377)
                     /gene="ybaE"
                     /locus_tag="ECs_0499"
                     /db_xref="GeneID:914601"
     CDS             complement(531677..533377)
                     /gene="ybaE"
                     /locus_tag="ECs_0499"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter periplasmic binding protein"
                     /protein_id="NP_308526.1"
                     /db_xref="GeneID:914601"
                     /translation="MRLLNRLNQYQRLWQPSAGKPQTVTVSELAERCFCSERHVRTLL
                     RQAQEAGWLEWQAQSGRGKRGQLRFLVTPESLRNAMMEKALETGKQQDVLELAQLAPG
                     ELRTLLQPFMGGQWQNDTPTLRIPYYRPLEPLQPGFLPGRAEQHLAGQIFSGLTRFDN
                     NTQRPIGDLAHHWETSADGLRWDFYLRSTLHWHNGDAVKASHLHQRLLMLLQLPALDQ
                     LFISVKRIEVTHPQCLTFFLHRPDYWLAHRLASYCSHLAHPQFPLIGTGPFRLTQFTA
                     ELVRLESHDYYHLRHPLLKAVEYWITPPLFEKDLGTSCRHPVQITIGKPEELQRVSQV
                     SSGISLGFCYLTLRKSPRLSLWQARKVISIIHQSGLLQTLEVGENLITASHALLPGWT
                     IPHWQVPDEVKLPKTLTLVYHLPIELHTMAERLQATLAAEGCELTIIFHNAKNWDDTT
                     LLAHADLMMGDRLIGEAPEYTLEQWLRCDPLWPHVFDAPAYAHLQSTLDAVQVMPDEE
                     NRFNALKAVFSQLMTDATLTPLFNYHYRISAPPGVNGVRLTPRGWFEFTEAWLPAPSQ
                     "
     misc_feature    complement(531692..533377)
                     /gene="ybaE"
                     /locus_tag="ECs_0499"
                     /note="DNA-binding transcriptional regulator SgrR of sgrS
                     sRNA, contains a MarR-type HTH domain and a
                     periplasmic-type solute-binding domain [Transcription];
                     Region: SgrR; COG4533"
                     /db_xref="CDD:226909"
     gene            533477..534295
                     /gene="cof"
                     /locus_tag="ECs_0500"
                     /db_xref="GeneID:914602"
     CDS             533477..534295
                     /gene="cof"
                     /locus_tag="ECs_0500"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrimidine pyrophosphate hydrolase"
                     /protein_id="NP_308527.2"
                     /db_xref="GeneID:914602"
                     /translation="MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGR
                     HALEMQHILGAISLDAYLITGNGTRVHSLEGELLHRDDLPADVAELVLYQQWDTRASM
                     HIFNDDGWFTGKEIPALLQAFVYSGFRYQIIDVKKMPLGSVTKICFCGDHDDLTRLQI
                     QLHEALGERAHLCFSATDCLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDAMNDRE
                     MLGSVGSGFIMGNAMPQLRAELPHLPVIGHCRNQAVSHYLTHWLDYPHLPYSPE"
     misc_feature    533477..534292
                     /gene="cof"
                     /locus_tag="ECs_0500"
                     /note="HMP-PP phosphatase; Region: PRK15126"
                     /db_xref="CDD:185080"
     gene            534447..534905
                     /gene="ybaO"
                     /locus_tag="ECs_0501"
                     /db_xref="GeneID:914603"
     CDS             534447..534905
                     /gene="ybaO"
                     /locus_tag="ECs_0501"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_308528.2"
                     /db_xref="GeneID:914603"
                     /translation="MLDKIDRKLLALLQQDCTLSLQALAEAVNLTTTPCWKRLKRLED
                     DGILIGKVALLDPEKIGLGLTAFVLIKTQHHSSEWYCRFVTVVTEMPEVLGFWRMAGE
                     YDYLMRVQVADMKRYDEFYKRLVNSVPGLSDVTSSFAMEQIKYTTSLPIE"
     misc_feature    534447..534899
                     /gene="ybaO"
                     /locus_tag="ECs_0501"
                     /note="DNA-binding transcriptional regulator, Lrp family
                     [Transcription]; Region: Lrp; COG1522"
                     /db_xref="CDD:224439"
     gene            534935..536707
                     /gene="mdlA"
                     /locus_tag="ECs_0502"
                     /db_xref="GeneID:914604"
     CDS             534935..536707
                     /gene="mdlA"
                     /locus_tag="ECs_0502"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug ABC transporter ATPase"
                     /protein_id="NP_308529.1"
                     /db_xref="GeneID:914604"
                     /translation="MRLFAQLSWYFRREWRRYLGAVALLVIIAMLQLVPPKVVGIVVD
                     GVTEQHFTTGQILMWIATMVLIAVVVYLLRYVWRVLLFGASYQLAVELREDYYRQLSR
                     QHPEFYLRHRTGDLMARATNDVDRVVFAAGEGVLTLVDSLVMGCAVLIMMSTQISWQL
                     TLFALLPMPVMAIMIKRNGDALHERFKLAQAAFSSLNDRTQESLTSIRMIKAFGLEDR
                     QSALFAADAEDTGKKNMRVARIDARFDPTIYIAIGMANLLAIGGGSWMVVQGSLTLGQ
                     LTSFMMYLGLMIWPMLALAWMFNIVERGSAAYSRIRAMLAEAPVVNDGSEPVPEGRGE
                     LDVNIHQFTYPQTDHPALENVNFALKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGD
                     IRFHDIPLTKLQLDSWRSRLAVVSQTPFLFSDTVANNIALGCPNATQQEIEHVARLAS
                     VHDDILRLPQGYDTEVGERGVMLSGGQKQRISIARALLVNAEILILDDALSAVDGRTE
                     HQILHNLRQWGQGRTVIISAHRLSALTEASEIIVMQHGHIAQRGNHDVLAQQSGWYRD
                     MYRYQQLEAALDDAPENREEAVDA"
     misc_feature    534998..536704
                     /gene="mdlA"
                     /locus_tag="ECs_0502"
                     /note="SmdA family multidrug ABC transporter
                     permease/ATP-binding protein; Region: PRK10789"
                     /db_xref="CDD:182732"
     gene            536700..538481
                     /gene="mdlB"
                     /locus_tag="ECs_0503"
                     /db_xref="GeneID:914605"
     CDS             536700..538481
                     /gene="mdlB"
                     /locus_tag="ECs_0503"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug ABC transporter ATPase"
                     /protein_id="NP_308530.1"
                     /db_xref="GeneID:914605"
                     /translation="MRSFSQLWPTLKRLLAYGSPWRKPLGIAVLMMWVAAAAEVSGPL
                     LISYFIDNMVAKNNLPLKVVAGLAAAYVGLQLFAAGLHYAQSLLFNRAAVGVVQQLRT
                     DVMDAALRQPLSEFDTQPVGQVISRVTNDTEVIRDLYVTVVATVLRSAALVGAMLVAM
                     FSLDWRMALVAIMIFPVVLVVMVIYQRYSTPIVRRVRAYLADINDGFNEIINGMSVIQ
                     QFRQQARFGERMGEASRSHYMARMQTLRLDGFLLRPLLSLFSSLILCGLLMLFGFSAS
                     GTIEVGVLYAFISYLGRLNEPLIELTTQQAMLQQAVVAGERVFELMDGPRQQYGNDDR
                     PLQSGTIEVDNVSFAYRDDNLVLKNINLSVPSRNFVALVGHTGSGKSTLASLLMGYYP
                     LTEGEIRLDGRPLSSLSHSALRQGVAMVQQDPVVLADTFLANVTLGRDISEERVWQAL
                     ETVQLAELARSMSDGIYTPLGEQGNNLSVGQKQLLALARVLVETPQILILDEATASID
                     SGTEQAIQHALAAVREHTTLVVIAHRLSTIVDADTILVLHRGQAVEQGTHQQLLAAQG
                     RYWQMYQLQLAGEELAASVREEESLSA"
     misc_feature    536700..538475
                     /gene="mdlB"
                     /locus_tag="ECs_0503"
                     /note="SmdB family multidrug efflux ABC transporter
                     permease/ATP-binding protein; Region: PRK10790"
                     /db_xref="CDD:182733"
     gene            538662..539000
                     /gene="glnK"
                     /locus_tag="ECs_0504"
                     /db_xref="GeneID:914607"
     CDS             538662..539000
                     /gene="glnK"
                     /locus_tag="ECs_0504"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulatory protein P-II 2"
                     /protein_id="NP_308531.1"
                     /db_xref="GeneID:914607"
                     /translation="MKLVTVIIKPFKLEDVREALSSIGIQGLTVTEVKGFGRQKGHAE
                     LYRGAEYSVNFLPKVKIDVAIADDQLDEVIDIVSKAAYTGKIGDGKIFVAELQRVIRI
                     RTGEADEAAL"
     misc_feature    538662..538997
                     /gene="glnK"
                     /locus_tag="ECs_0504"
                     /note="P-II family nitrogen regulator; Region: PRK10665"
                     /db_xref="CDD:182629"
     gene            539030..540316
                     /gene="amtB"
                     /locus_tag="ECs_0505"
                     /db_xref="GeneID:914608"
     CDS             539030..540316
                     /gene="amtB"
                     /locus_tag="ECs_0505"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="NP_308532.1"
                     /db_xref="GeneID:914608"
                     /translation="MKIATIKTGLASLAMLPGLVMAAPAVADKADNAFMMICTALVLF
                     MTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINW
                     LMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTL
                     SYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLIGKRVGFGKEAFKPH
                     NLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRG
                     KPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLKRLLRVDDPC
                     DVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVA
                     FIGYKLADLTVGLRVPEEQEREGLDVNSHGENAYNA"
     misc_feature    539030..540313
                     /gene="amtB"
                     /locus_tag="ECs_0505"
                     /note="ammonium transporter AmtB; Region: PRK10666"
                     /db_xref="CDD:182630"
     gene            complement(540365..541225)
                     /gene="tesB"
                     /locus_tag="ECs_0506"
                     /db_xref="GeneID:914609"
     CDS             complement(540365..541225)
                     /gene="tesB"
                     /locus_tag="ECs_0506"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase 2"
                     /protein_id="NP_308533.1"
                     /db_xref="GeneID:914609"
                     /translation="MSQALKNLLTLLNLEKIEEGLFRGQSEDLGLRQVFGGQVVGQAL
                     YAAKETVPEERLVHSFHSYFLRPGDSKKPIIYDVETLRDGNSFSARRVAAIQNGKPIF
                     YMTASFQAPEAGFEHQKTMPSAPAPDGLPSETQIAQSLAHLLPPVLKDKFICDRPLEV
                     RPVEFHNPLKGHVAEPHRQVWIRANGSVPDDLRVHQYLLGYASDLNFLPVALQPHGIG
                     FLEPGIQIATIDHSMWFHRPFNLNEWLLYSVESTSASSARGFVRGEFYTQDGVLVAST
                     VQEGVMRNHN"
     misc_feature    complement(540368..541225)
                     /gene="tesB"
                     /locus_tag="ECs_0506"
                     /note="acyl-CoA thioesterase II; Provisional; Region:
                     PRK10526"
                     /db_xref="CDD:182519"
     gene            541443..542015
                     /gene="ybaY"
                     /locus_tag="ECs_0507"
                     /db_xref="GeneID:914610"
     CDS             541443..542015
                     /gene="ybaY"
                     /locus_tag="ECs_0507"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein"
                     /protein_id="NP_308534.3"
                     /db_xref="GeneID:914610"
                     /translation="MKLVHMASGLAVAIALAACADKSADIQTPAPAANTSISATQQPA
                     IQQPNVSGTVWIRQKVALPPDAVLTVTLSDASLADAPSKVLAQKAVRTEGKQSPFSFV
                     LPFNPADVQPNARILLSAAITVNDKLVFITDTVQPVINQGGTKADLTLVPVQQTAVPV
                     QASGGATTTVPSTSPTQVNPSSAVPAPTQY"
     misc_feature    541443..541934
                     /gene="ybaY"
                     /locus_tag="ECs_0507"
                     /note="Uncharacterized lipoprotein YbaY [Function
                     unknown]; Region: YbaY; COG3126"
                     /db_xref="CDD:225668"
     gene            complement(542048..542359)
                     /gene="ybaZ"
                     /locus_tag="ECs_0508"
                     /db_xref="GeneID:914611"
     CDS             complement(542048..542359)
                     /gene="ybaZ"
                     /locus_tag="ECs_0508"
                     /codon_start=1
                     /transl_table=11
                     /product="6-O-methylguanine DNA methyltransferase"
                     /protein_id="NP_308535.2"
                     /db_xref="GeneID:914611"
                     /translation="MEKEDSFPQRVWQIVAAIPEGYVTTYGDVAKLAGSPRAARQVGG
                     VLKRLPEGSTLPWHRVVNRHGTISLTGPDLQRQRQALLAEGVMVSGSGQIDLQRYRWN
                     Y"
     misc_feature    complement(542051..542359)
                     /gene="ybaZ"
                     /locus_tag="ECs_0508"
                     /note="Alkylated DNA nucleotide flippase Atl1,
                     participates in nucleotide excision repair, Ada-like
                     DNA-binding domain [Transcription]; Region: Atl1; COG3695"
                     /db_xref="CDD:226219"
     misc_feature    complement(order(542153..542155,542174..542176,
                     542189..542191,542213..542215,542219..542224,
                     542231..542233,542237..542242,542246..542248,
                     542255..542257,542279..542284,542336..542341))
                     /gene="ybaZ"
                     /locus_tag="ECs_0508"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:119438"
     misc_feature    complement(order(542108..542110,542180..542182,
                     542186..542191,542282..542284))
                     /gene="ybaZ"
                     /locus_tag="ECs_0508"
                     /note="active site"
                     /db_xref="CDD:119438"
     gene            542738..543091
                     /gene="ybaA"
                     /locus_tag="ECs_0509"
                     /db_xref="GeneID:914613"
     CDS             542738..543091
                     /gene="ybaA"
                     /locus_tag="ECs_0509"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308536.1"
                     /db_xref="GeneID:914613"
                     /translation="MKYVDGFVVAVPADKKDAYREMAAKAAPLFKEFGALRIVECWAS
                     DVPDGKVTDFRMAVKAEENEEVVFSWIEYPSKEVRDAANQKMMSDPRMKEFGESMPFD
                     GKRMIYGGFESIIDE"
     misc_feature    542738..543088
                     /gene="ybaA"
                     /locus_tag="ECs_0509"
                     /note="Uncharacterized conserved protein YbaA, DUF1428
                     family [Function unknown]; Region: YbaA; COG5507"
                     /db_xref="CDD:227794"
     gene            complement(543133..544683)
                     /gene="ylaB"
                     /locus_tag="ECs_0510"
                     /db_xref="GeneID:914614"
     CDS             complement(543133..544683)
                     /gene="ylaB"
                     /locus_tag="ECs_0510"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-anchored cyclic-di-GMP
                     phosphodiesterase"
                     /protein_id="NP_308537.2"
                     /db_xref="GeneID:914614"
                     /translation="MRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTY
                     SSRVAIRANKVATQGKDALQELERWQGADCSEAHLMEMRRVSYSYRYIQEVVYIDNNV
                     PQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPAS
                     FIDVIPYSSWQIDAAIIGNAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILP
                     FPEMNISIITWASSKMLQKGWHRQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQ
                     DAIENRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSPDSFIPLAQQTGLSEPL
                     TLLIIRSVFEDMGDWLRQHPQQHISINLESTVLTSEKIPQLLREMINHYQVNPRQIAL
                     ELTEREFADPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVD
                     ALEYKNVTPHIIEMAKTLKLKMVAEGIETSKQEEWLRQHGVHYGQGWLYSKALPKEDF
                     LRWAEQHL"
     misc_feature    complement(543136..544683)
                     /gene="ylaB"
                     /locus_tag="ECs_0510"
                     /note="Environmental sensor c-di-GMP phosphodiesterase,
                     contains periplasmic CSS-motif sensor and cytoplasmic EAL
                     domain [Signal transduction mechanisms]; Region: YjcC;
                     COG4943"
                     /db_xref="CDD:227279"
     gene            complement(544847..545317)
                     /gene="ylaC"
                     /locus_tag="ECs_0511"
                     /db_xref="GeneID:914615"
     CDS             complement(544847..545317)
                     /gene="ylaC"
                     /locus_tag="ECs_0511"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308538.2"
                     /db_xref="GeneID:914615"
                     /translation="MTEIQRLLTETIESLNTREKRDNKPRFSISFIRKHPGLFIGMYV
                     AFFATLAVMLQSETLSGSVWLLVVLFILLNGFFFFDVYPRYRYEDIDVLDFRVCYNGE
                     WYNTRFVPAALVEAILNSPRVADVHKEQLQKMIVRKGELSFYDIFTLARAESTS"
     misc_feature    complement(544859..545317)
                     /gene="ylaC"
                     /locus_tag="ECs_0511"
                     /note="Inner membrane protein YlaC; Region: YlaC;
                     pfam10777"
                     /db_xref="CDD:431490"
     gene            complement(545433..545984)
                     /gene="maa"
                     /locus_tag="ECs_0512"
                     /db_xref="GeneID:914616"
     CDS             complement(545433..545984)
                     /gene="maa"
                     /locus_tag="ECs_0512"
                     /codon_start=1
                     /transl_table=11
                     /product="maltose O-acetyltransferase"
                     /protein_id="NP_308539.1"
                     /db_xref="GeneID:914616"
                     /translation="MSTEKEKMIAGELYRSADETLSRDRLRARQLIHRYNHSLAEEHT
                     LRQQILADLFGQVTEAYIEPTFRCDYGYNIFLGNNFFANFDCVMLDVCPIRIGDNCML
                     ALGVHIYTATHPIDPVARNSGAELGKPVTIGNNVWIGGRAVINPGVTIGDNVVVASGA
                     VVTKDVPDNVVVGGNPARIIKKL"
     misc_feature    complement(545436..545984)
                     /gene="maa"
                     /locus_tag="ECs_0512"
                     /note="maltose O-acetyltransferase; Provisional; Region:
                     PRK10092"
                     /db_xref="CDD:182235"
     misc_feature    complement(order(545451..545453,545457..545468,
                     545493..545498,545502..545504,545511..545516,
                     545550..545552,545565..545570,545574..545576,
                     545610..545612,545616..545621,545640..545642,
                     545646..545648,545652..545654,545658..545660,
                     545676..545678,545682..545684,545712..545714,
                     545718..545720,545736..545738,545742..545744,
                     545778..545780,545910..545912,545937..545939))
                     /gene="maa"
                     /locus_tag="ECs_0512"
                     /note="active site"
                     /db_xref="CDD:100047"
     misc_feature    complement(order(545610..545612,545616..545621,
                     545646..545648,545652..545654,545682..545684,
                     545712..545714,545718..545720,545736..545738,
                     545742..545744,545778..545780,545910..545912,
                     545937..545939))
                     /gene="maa"
                     /locus_tag="ECs_0512"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:100047"
     misc_feature    complement(order(545460..545462,545496..545498,
                     545508..545513,545520..545522,545526..545528,
                     545550..545552,545559..545567,545574..545576,
                     545580..545582,545601..545603,545607..545609,
                     545625..545630,545634..545642,545646..545648,
                     545658..545660,545664..545666,545670..545672,
                     545682..545684,545688..545690,545730..545735,
                     545781..545786,545790..545792,545865..545867,
                     545886..545888,545898..545900,545907..545909))
                     /gene="maa"
                     /locus_tag="ECs_0512"
                     /note="trimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:100047"
     misc_feature    complement(order(545457..545459,545463..545468,
                     545493..545498,545511..545516,545550..545552,
                     545565..545570,545574..545576,545640..545642,
                     545646..545648,545652..545654,545658..545660))
                     /gene="maa"
                     /locus_tag="ECs_0512"
                     /note="CoA binding site [chemical binding]; other site"
                     /db_xref="CDD:100047"
     gene            complement(546156..546374)
                     /gene="hha"
                     /locus_tag="ECs_0513"
                     /db_xref="GeneID:914617"
     CDS             complement(546156..546374)
                     /gene="hha"
                     /locus_tag="ECs_0513"
                     /codon_start=1
                     /transl_table=11
                     /product="modulator of gene expression with H-NS"
                     /protein_id="NP_308540.1"
                     /db_xref="GeneID:914617"
                     /translation="MSEKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFY
                     SAADHRLAELTMNKLYDKIPSSVWKFIR"
     misc_feature    complement(546159..546374)
                     /gene="hha"
                     /locus_tag="ECs_0513"
                     /note="hemolysin expression modulator Hha; Region:
                     PRK10945"
                     /db_xref="CDD:182856"
     gene            complement(546400..546774)
                     /gene="tomB"
                     /locus_tag="ECs_0514"
                     /db_xref="GeneID:914618"
     CDS             complement(546400..546774)
                     /gene="tomB"
                     /locus_tag="ECs_0514"
                     /codon_start=1
                     /transl_table=11
                     /product="Hha toxicity attenuator TomB"
                     /protein_id="NP_308541.1"
                     /db_xref="GeneID:914618"
                     /translation="MDEYSPKRHDIAQLKFLCETLYHDCLANLEESNHGWVNDPTSAI
                     NLQLNELIEHIATFALNYKIKYNEDNKLIEQIDEYLDDTFMLFSSYGINMQDLQKWRK
                     SGNRLFRCFVNATKENPASLSC"
     misc_feature    complement(546409..546774)
                     /gene="tomB"
                     /locus_tag="ECs_0514"
                     /note="Hha toxicity modulator TomB; Region: PRK10667"
                     /db_xref="CDD:182631"
     gene            complement(547320..550469)
                     /gene="acrB_1"
                     /locus_tag="ECs_0515"
                     /db_xref="GeneID:914619"
     CDS             complement(547320..550469)
                     /gene="acrB_1"
                     /locus_tag="ECs_0515"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux system protein"
                     /protein_id="NP_308542.1"
                     /db_xref="GeneID:914619"
                     /translation="MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVT
                     ISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADI
                     AQVQVQNKLQLAMPLLPQEVQQQGVSIEKSSSSFLMVVGVINTDGTMTQEDISDYVAA
                     NMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQ
                     LGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYD
                     IIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVK
                     ISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLS
                     AVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEG
                     KKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPD
                     EDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNT
                     GIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDF
                     ELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALG
                     VSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQM
                     VPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVG
                     YDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALL
                     AATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRL
                     RPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVR
                     RRFSRKNEDIEHNHTVDHH"
     misc_feature    complement(547323..550469)
                     /gene="acrB_1"
                     /locus_tag="ECs_0515"
                     /note="multidrug efflux RND transporter permease subunit
                     AcrB; Region: PRK15127"
                     /db_xref="CDD:185081"
     gene            complement(550492..551685)
                     /gene="acrA"
                     /locus_tag="ECs_0516"
                     /db_xref="GeneID:914620"
     CDS             complement(550492..551685)
                     /gene="acrA"
                     /locus_tag="ECs_0516"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux system"
                     /protein_id="NP_308543.1"
                     /db_xref="GeneID:914620"
                     /translation="MNKNRGFTPLAVVLMLSGSLALTGCDDKQAQQGGQQMPAVGVVT
                     VKTEPLQITTELPGRTSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQ
                     ATYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAA
                     KAAVETARINLAYTKVTSPISGRIGKSNVTEGALVQNGQATALATVQQLDPIYVDVTQ
                     SSNDFLRLKQELANGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVDQTTGSITL
                     RAIFPNPDHTLLPGMFVRARLEEGLNPNAILVPQQGVTRTPRGDATVLVVGADDKVET
                     RPIVASQAIGDKWLVTEGLKAGDRVVISGLQKVRPGVQVKAQEVTADNNQQAASGAQP
                     EQSKS"
     misc_feature    complement(550495..551685)
                     /gene="acrA"
                     /locus_tag="ECs_0516"
                     /note="multidrug efflux RND transporter periplasmic
                     adaptor subunit AcrA; Region: PRK15030"
                     /db_xref="CDD:184990"
     gene            551827..552474
                     /gene="acrR"
                     /locus_tag="ECs_0517"
                     /db_xref="GeneID:914621"
     CDS             551827..552474
                     /gene="acrR"
                     /locus_tag="ECs_0517"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="NP_308544.1"
                     /db_xref="GeneID:914621"
                     /translation="MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVT
                     RGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPSDPLSVLREILIHVLESTVT
                     EERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMT
                     RRAAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE"
     misc_feature    551827..552471
                     /gene="acrR"
                     /locus_tag="ECs_0517"
                     /note="DNA-binding transcriptional repressor AcrR;
                     Provisional; Region: PRK10668"
                     /db_xref="CDD:182632"
     gene            552602..555964
                     /gene="mscK"
                     /locus_tag="ECs_0518"
                     /db_xref="GeneID:914622"
     CDS             552602..555964
                     /gene="mscK"
                     /locus_tag="ECs_0518"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel protein"
                     /protein_id="NP_308545.1"
                     /db_xref="GeneID:914622"
                     /translation="MTMFQYYKRSRHFVFSAFIAFVFVLLCQNTAFARASSNGDLPTK
                     ADLQAQLDSLNKQKDLSAQDKLVQQDLTDTLATLDKIDRVKEETVQLRQKVAEAPEKM
                     RQATAALTALSDVDNDEETRKILSTLSLRQLETRVAQALDDLQNAQNDLASYNSQLVS
                     LQTQPERVQNAMYNASQQLQQIRSRLDGTDVGETALRPSQKVLMQAQQALLNAEIDQQ
                     RKSLEGNTVLQDTLQKQRDYVTANSARLEHQLQLLQEAVNSKRLTLTEKTAQEAVSPD
                     EAARIQANPLVKQELEINQQLSQRLITATENGNQLMQQNIKVKNWLERALQSERNIKE
                     QIAVLKGSLLLSRILYQQQQTLPSADELENMTNRIADLRLEQFEVNQQRDALFQSDAF
                     VNKLEEGHTNEVNSEVHDALLQVVDMRRELLDQLNKQLGNQLMMAINLQINQQQLMSV
                     SKNLKSILTQQIFWVNSNRPMDWDWIKAFPQSLKDEFKSMKITVNWEKAWPAVFIAFL
                     AGLPLLLIAGLIHWRLGWLKAYQQKLASAVGSLRNDSQLNTPKAILIDLIRALPVCLI
                     ILAVGLILLTMQLNISELLWSFSKKLAIFWLVFGLCWKVLEKNGVAVRHFGMPEQQTS
                     HWRRQIVRISLALLPIHFWSVVAELSPLHLMDDVLGQAMIFFNLLLIAFLVWPMCRES
                     WRDKESHTMRLVTITVLSIIPIALMVLTATGYFYTTLRLSGRWIETVYLVIIWNLLYQ
                     TVLRGLSVAARRIAWRRALARRQNLVKEGAEGAEPPEEPTIALEQVNQQTLRITMLLM
                     FALFGVMFWAIWSDLITVFSYLDSITLWHYNGTEAGAAVVKNVTMGSLLFAIIASMVA
                     WALIRNLPGLLEVLVLSRLNMRQGASYAITTILNYIIIAVGAMTVFGSLGVSWDKLQW
                     LAAALSVGLGFGLQEIFGNFVSGLIILFERPVRIGDTVTIGSFSGTVSKIRIRATTIT
                     DFDRKEVIIPNKAFVTERLINWSLTDTTTRLVIRLGVAYGSDLEKVRKVLLKAATEHP
                     RVMHEPMPEVFFTAFGASTLDHELRLYVRELRDRSRTVDELNRTIDQLCRENDINIAF
                     NQLEVHLHNEKGDEVTEVKRDYKGDDPTPAVG"
     misc_feature    552620..555961
                     /gene="mscK"
                     /locus_tag="ECs_0518"
                     /note="mechanosensitive channel MscK; Region: PRK11281"
                     /db_xref="CDD:236892"
     gene            complement(556003..556167)
                     /gene="ybaM"
                     /locus_tag="ECs_0519"
                     /db_xref="GeneID:914623"
     CDS             complement(556003..556167)
                     /gene="ybaM"
                     /locus_tag="ECs_0519"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308546.1"
                     /db_xref="GeneID:914623"
                     /translation="MSLENAPDDVKLAVDLIVLLEENQIPARTVLRALDIVKRDYEKK
                     LQSDEASQSE"
     misc_feature    complement(556027..556167)
                     /gene="ybaM"
                     /locus_tag="ECs_0519"
                     /note="hypothetical protein; Provisional; Region:
                     PRK11038"
                     /db_xref="CDD:182920"
     gene            complement(556181..556708)
                     /gene="priC"
                     /locus_tag="ECs_0520"
                     /db_xref="GeneID:914624"
     CDS             complement(556181..556708)
                     /gene="priC"
                     /locus_tag="ECs_0520"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein PriC"
                     /protein_id="NP_308547.1"
                     /db_xref="GeneID:914624"
                     /translation="MKTALLLEKLEGQLATLRQRCAPVSQFATLSARFNRHLFQTRAT
                     TLQACLDKAGDNLAALRHAVEQQQLPQVAWLAEHLAAQLEAIAREATAWSLREWDSAP
                     PQIARWQRKRIQHQDFERRLREMVAERRARLARVTDLVEQQTLHREVEAYEARLARCR
                     HALEKIENRLARLTR"
     misc_feature    complement(556184..556696)
                     /gene="priC"
                     /locus_tag="ECs_0520"
                     /note="primosomal replication protein N''; Provisional;
                     Region: PRK10093"
                     /db_xref="CDD:182236"
     gene            556778..557155
                     /gene="ybaN"
                     /locus_tag="ECs_0521"
                     /db_xref="GeneID:914625"
     CDS             556778..557155
                     /gene="ybaN"
                     /locus_tag="ECs_0521"
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein"
                     /protein_id="NP_308548.1"
                     /db_xref="GeneID:914625"
                     /translation="MQRIILIIIGWLAVVLGTLGVVLPVLPTTPFILLAAWCFARSSP
                     RFHAWLLYRSWFGSYLRFWQKHHAMPRGVKPRAILLILLTFAISLWFVQMPWVRIMLL
                     VILACLLFYMWRIPVIDEKQEKH"
     misc_feature    556778..557152
                     /gene="ybaN"
                     /locus_tag="ECs_0521"
                     /note="DUF454 family protein; Region: PRK10527"
                     /db_xref="CDD:182520"
     gene            557308..557859
                     /gene="apt"
                     /locus_tag="ECs_0522"
                     /db_xref="GeneID:914626"
     CDS             557308..557859
                     /gene="apt"
                     /locus_tag="ECs_0522"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="NP_308549.1"
                     /db_xref="GeneID:914626"
                     /translation="MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALS
                     IDLLVERYKNAGINKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDL
                     EYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFD
                     LGGEQRLEKQGITSYSLVPFPGH"
     misc_feature    557323..557853
                     /gene="apt"
                     /locus_tag="ECs_0522"
                     /note="adenine phosphoribosyltransferase; Provisional;
                     Region: PRK02304"
                     /db_xref="CDD:235028"
     misc_feature    order(557497..557499,557503..557505,557683..557691,
                     557695..557709,557779..557781)
                     /gene="apt"
                     /locus_tag="ECs_0522"
                     /note="active site"
                     /db_xref="CDD:206754"
     gene            557988..559919
                     /gene="dnaX"
                     /locus_tag="ECs_0523"
                     /db_xref="GeneID:914627"
     CDS             557988..559919
                     /gene="dnaX"
                     /locus_tag="ECs_0523"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III/DNA elongation factor III tau
                     and gamma subunits DnaX"
                     /protein_id="NP_308550.1"
                     /db_xref="GeneID:914627"
                     /translation="MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFS
                     GTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTKVE
                     DTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ
                     KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDAL
                     SLTDQAIASGDGQVSTQAVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGI
                     EWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTIPPTDIQLYYQTLLI
                     GRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQSFAPVAPTAVMTPTQVPPQ
                     PQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATKAKKSEPAAATRARPVNNAALERL
                     ASVTDRVQARPVPSALEKAPAKKEAYRWKATTPVMQQKEVVATPKALKKALEHEKTPE
                     LAAKLAAEAIERDAWAAQVSQLSLPKLVEQVALNAWKEESDNAVCLHLRSSQRHLNNR
                     GAQQKLAEALSMLKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNI
                     QTLRRFFDAELDEDSIRPI"
     misc_feature    557988..559916
                     /gene="dnaX"
                     /locus_tag="ECs_0523"
                     /note="DNA polymerase III subunits gamma and tau;
                     Validated; Region: PRK07994"
                     /db_xref="CDD:236138"
     gene            559972..560301
                     /gene="ybaB"
                     /locus_tag="ECs_0524"
                     /db_xref="GeneID:914628"
     CDS             559972..560301
                     /gene="ybaB"
                     /locus_tag="ECs_0524"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308551.1"
                     /db_xref="GeneID:914628"
                     /translation="MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKV
                     TINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLP
                     PGFKMPF"
     misc_feature    559972..560289
                     /gene="ybaB"
                     /locus_tag="ECs_0524"
                     /note="Conserved DNA-binding protein YbaB (function
                     unknown) [General function prediction only]; Region: YbaB;
                     COG0718"
                     /db_xref="CDD:223790"
     gene            560301..560906
                     /gene="recR"
                     /locus_tag="ECs_0525"
                     /db_xref="GeneID:914629"
     CDS             560301..560906
                     /gene="recR"
                     /locus_tag="ECs_0525"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="NP_308552.1"
                     /db_xref="GeneID:914629"
                     /translation="MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLA
                     QALTRAMSEIGHCADCRTFTEQEVCNICSNPRRQENGQICVVESPADIYAIEQTGQFS
                     GRYFVLMGHLSPLDGIGPDDIGLDRLEQRLAEEKITEVILATNPTVEGEATANYIAEL
                     CAQYDVEASRIAHGVPVGGELEMVDGTTLSHSLAGRHKIRF"
     misc_feature    560301..560897
                     /gene="recR"
                     /locus_tag="ECs_0525"
                     /note="Recombinational DNA repair protein RecR
                     [Replication, recombination and repair]; Region: RecR;
                     COG0353"
                     /db_xref="CDD:223430"
     gene            561016..562890
                     /gene="htpG"
                     /locus_tag="ECs_0526"
                     /db_xref="GeneID:914630"
     CDS             561016..562890
                     /gene="htpG"
                     /locus_tag="ECs_0526"
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein Hsp90"
                     /protein_id="NP_308553.1"
                     /db_xref="GeneID:914630"
                     /translation="MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAAD
                     KLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGT
                     KSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEG
                     EYTVADITKEDRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDG
                     ETVISWEKINKAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTS
                     LLYIPSQAPWDMWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNV
                     SREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFAN
                     QEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELL
                     RKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKAL
                     TPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEVKY
                     IFELNPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLVS
                     "
     misc_feature    561025..562884
                     /gene="htpG"
                     /locus_tag="ECs_0526"
                     /note="heat shock protein 90; Provisional; Region:
                     PRK05218"
                     /db_xref="CDD:235366"
     gene            563011..563715
                     /gene="adk"
                     /locus_tag="ECs_0527"
                     /db_xref="GeneID:914631"
     CDS             563011..563715
                     /gene="adk"
                     /locus_tag="ECs_0527"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="NP_308554.2"
                     /db_xref="GeneID:914631"
                     /translation="MVVSFIAFSKNSTHFKGIFAMRIILLGAPGAGKGTQAQFIMEKY
                     GIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFL
                     LDGFPRTIPQADAMKEAGINVDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPP
                     KVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDG
                     TKPVAEVRADLEKILG"
     misc_feature    563071..563712
                     /gene="adk"
                     /locus_tag="ECs_0527"
                     /note="adenylate kinase; Reviewed; Region: adk; PRK00279"
                     /db_xref="CDD:234711"
     gene            563847..564809
                     /gene="hemH"
                     /locus_tag="ECs_0528"
                     /db_xref="GeneID:914632"
     CDS             563847..564809
                     /gene="hemH"
                     /locus_tag="ECs_0528"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="NP_308555.1"
                     /db_xref="GeneID:914632"
                     /translation="MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTSRLL
                     WWPLLRGVILPLRSPRVAKLYASVWMEGGSPLMVYSRQQQQALAQRLPETPVALGMSY
                     GSPSLESAVDELLAEHVDHIVVLPLYPQFSCSTVGAVWDELARILARKRSIPGISFIR
                     DYADNHDYINALANSVRASFAKHGEPDLLLLSYHGIPQRYADEGDDYPQRCRTTTREL
                     ASALGMAPEKVMMTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLET
                     LEEIAEQNREVFLGAGGKKYEYIPALNATPEHIEMMANLVAAYR"
     misc_feature    563847..564806
                     /gene="hemH"
                     /locus_tag="ECs_0528"
                     /note="ferrochelatase; Region: hemH; TIGR00109"
                     /db_xref="CDD:272909"
     gene            complement(564806..565765)
                     /gene="aes"
                     /locus_tag="ECs_0529"
                     /db_xref="GeneID:914633"
     CDS             complement(564806..565765)
                     /gene="aes"
                     /locus_tag="ECs_0529"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl esterase"
                     /protein_id="NP_308556.1"
                     /db_xref="GeneID:914633"
                     /translation="MKPENKLPVLDLISAEMKTVVNTLQPDLPPWPATGTIAEQRQYY
                     TLERRFWNAGAPEMATKAYMVPTKYGQVETRLFCPQPDSPATLFYLHGGGFILGNLDT
                     HDRIMRLLASYSQCTVIGIDYTLSPEARFPQVIEEIVAACCYFHQQAEDYQINMSRIG
                     FAGDSAGAMLALASALWLRDKQIDCGKVAGVLLWYGLYGLRDSVTRRLLGGVWDGLTQ
                     QDLQMYEEAYLSNDADRESPYYCLFNNDLTREVPPCFIAGAEFDPLLDDSRLLYQTLA
                     AHQQPCEFKLYPGTLHAFLHYSRMMKTADEALRDGAQFFTAQL"
     misc_feature    complement(564809..565756)
                     /gene="aes"
                     /locus_tag="ECs_0529"
                     /note="acetyl esterase; Region: PRK10162"
                     /db_xref="CDD:236660"
     gene            565917..567221
                     /gene="gsk"
                     /locus_tag="ECs_0530"
                     /db_xref="GeneID:914634"
     CDS             565917..567221
                     /gene="gsk"
                     /locus_tag="ECs_0530"
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/guanosine kinase"
                     /protein_id="NP_308557.1"
                     /db_xref="GeneID:914634"
                     /translation="MKFPGKRKSKHYFPVNARDPLLQQFQPENETSAAWVVGIDQTLV
                     DIEAKVDDEFIERYGLSAGHSLVIEDDVAEALYQELKQKNLITHQFAGGTIGNTMHNY
                     SVLADDRSVLLGVMCSNIEIGSYAYRYLCNTSSRTDLNYLQGVDGPIGRCFTLIGESG
                     ERTFAISPGHMNQLRAESIPEDVIAGASALVLTSYLVRCKPGEPMPEATMKAIEYAKK
                     YNVPVVLTLGTKFVIAENPQWWQQFLKDHVSILAMNEDEAEALTGESDPLLASDKALD
                     WVDLVLCTAGPIGLYMAGFTEDEAKRKTQHPLLPGAIAEFNQYEFSRAMRHKDCQNPL
                     RVYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANSYHRSNVPNSSKHKFTWLTYS
                     SLAQVCKYANRVSYQVLNQHSPRLTRGLPEREDSLEESYWDR"
     misc_feature    565917..567218
                     /gene="gsk"
                     /locus_tag="ECs_0530"
                     /note="inosine/guanosine kinase; Provisional; Region:
                     PRK15074"
                     /db_xref="CDD:185033"
     misc_feature    order(566205..566207,566979..566981,566988..566990)
                     /gene="gsk"
                     /locus_tag="ECs_0530"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238177"
     misc_feature    order(566676..566678,566766..566768,566973..566975,
                     566982..566987)
                     /gene="gsk"
                     /locus_tag="ECs_0530"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:238177"
     gene            complement(567354..569030)
                     /gene="ybaL"
                     /locus_tag="ECs_0531"
                     /db_xref="GeneID:914635"
     CDS             complement(567354..569030)
                     /gene="ybaL"
                     /locus_tag="ECs_0531"
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane NAD(P)-binding transporter"
                     /protein_id="NP_308558.1"
                     /db_xref="GeneID:914635"
                     /translation="MHHATPLITTIVGGLVLAFILGMLANKLRISPLVGYLLAGVLAG
                     PFTPGFVADTKLAPELAELGVILLMFGVGLHFSLKDLMAVKAIAIPGAIAQIAVATLL
                     GMALSAVLGWSLMTGIVFGLCLSTASTVVLLRALEERQLIDSQRGQIAIGWLIVEDLV
                     MVLTLVLLPAVAGMMEQGDVGFATLAVDMGITIGKVIAFIAIMMLVGRRLVPWIMARS
                     AATGSRELFTLSVLALALGIAFGAVELFDVSFALGAFFAGMVLNESELSHRAAHDTLP
                     LRDAFAVLFFVSVGMLFDPLILIQQPLAVLATLAIILFGKSLAAFFLVRLFGHSQRTA
                     LTIAASLAQIGEFAFILAGLGMALNLLPQAGQNLVLAGAILSIMLNPVLFALLEKYLA
                     KTETLEEQTLEEAIEEEKQIPVDICNHALLVGYGRVGSLLGEKLLASDIPLVVIETSR
                     TRVDELRERGVRAVLGNAANEEIMQLAHLECAKWLILTIPNGYEAGEIVASARAKNPD
                     IEIIARAHYDDEVAYITERGANQVVMGEREIARTMLELLETPPAGEVVTG"
     misc_feature    complement(567357..569030)
                     /gene="ybaL"
                     /locus_tag="ECs_0531"
                     /note="putative cation:proton antiport protein;
                     Provisional; Region: PRK10669"
                     /db_xref="CDD:182633"
     gene            complement(569267..570487)
                     /gene="fsr"
                     /locus_tag="ECs_0532"
                     /db_xref="GeneID:914636"
     CDS             complement(569267..570487)
                     /gene="fsr"
                     /locus_tag="ECs_0532"
                     /codon_start=1
                     /transl_table=11
                     /product="fosmidomycin resistance protein"
                     /protein_id="NP_308559.1"
                     /db_xref="GeneID:914636"
                     /translation="MAMSEQTQPVAGAAASTTKARTSFGILGAISLSHLLNDMIQSLI
                     LAIYPLLQSEFSLTFMQIGMITLTFQLASSLLQPVVGYWTDKYPMPWSLPIGMCFTLS
                     GLVLLALAGSFGAVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFG
                     SSLGPLLAAVIIAPYGKGNVAWFVLAALLAIVVLAQISRWYSAQHRMNKGKPKATIIN
                     PLPRNKVVLAVSILLILIFSKYFYMASISSYYTFYLMQKFGLSIQNAQLHLFAFLFAV
                     AAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLILPYASLHWTGVLTVIIGFILASAFS
                     AILVYAQELLPGRIGMVSGLFFGFAFGMGGLGAAVLGLIADHTSIELVYKICAFLPLL
                     GMLTIFLPDNRHKD"
     misc_feature    complement(569294..570400)
                     /gene="fsr"
                     /locus_tag="ECs_0532"
                     /note="Fosmidomycin resistance protein of the Major
                     Facilitator Superfamily of transporters; Region: MFS_FsR;
                     cd17478"
                     /db_xref="CDD:341031"
     misc_feature    complement(order(569399..569401,569408..569413,
                     569420..569425,569432..569434,569477..569479,
                     569489..569491,569501..569506,569648..569650,
                     569660..569662,569744..569746,569753..569761,
                     569768..569773,569780..569782,570005..570007,
                     570014..570019,570026..570028,570083..570085,
                     570092..570100,570104..570109,570257..570259,
                     570353..570355,570362..570367,570374..570379))
                     /gene="fsr"
                     /locus_tag="ECs_0532"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]; other site"
                     /db_xref="CDD:341031"
     gene            570705..572357
                     /gene="ushA"
                     /locus_tag="ECs_0533"
                     /db_xref="GeneID:914637"
     CDS             570705..572357
                     /gene="ushA"
                     /locus_tag="ECs_0533"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-sugar hydrolase"
                     /protein_id="NP_308560.1"
                     /db_xref="GeneID:914637"
                     /translation="MKLLQRGVALALLTTFTLASEAALAYEQDKTYKITVLHTNDHHG
                     HFWRNEYGEYGLAAQKTLVDGIRKEVAAEGGSVLLLSGGDINTGVPESDLQDAEPDFR
                     GMNLVGYDAMAIGNHEFDNPLTVLRQQEKWAKFPLLSANIYQKSTGERLFKPWALFKR
                     QDLKIAVIGLTTDDTAKLGNPENFTDIEFRKPADEAKLVIQELQQTEKPDIIIAATHM
                     GHYDNGDHGSNAPGDVEMARALPAGSLAMIVGGHSQDPVCMAAENKKQVDYVPGTPCK
                     PDQQNGIWIVQAHEWGKYVGRADFEFRNGEMKMVNYQLIPVNLKKKVTWEDGKSERVL
                     YTPEIAENQQMISLLSPFQNKGKAQLEVKIGETNGRLEGDRDKVRFVQTNMGRLILAA
                     QMDRTGADFAVMSGGGIRDSIEAGDISYKNVLKVQPFGNVVVYADMTGKEVIDYLTAV
                     AQMKPDSGAYPQFANVSFVAKDGKLNDLKIKGEPVDPAKTYRMATLNFNATGGDGYPR
                     LDNKPGYVNTGFIDAEVLKAYIQKSSPLDVSVYEPKGEVSWQ"
     misc_feature    570705..572354
                     /gene="ushA"
                     /locus_tag="ECs_0533"
                     /note="bifunctional UDP-sugar hydrolase/5'-nucleotidase
                     periplasmic precursor; Reviewed; Region: ushA; PRK09558"
                     /db_xref="CDD:236566"
     gene            complement(572394..572873)
                     /gene="ybaK"
                     /locus_tag="ECs_0534"
                     /db_xref="GeneID:914638"
     CDS             complement(572394..572873)
                     /gene="ybaK"
                     /locus_tag="ECs_0534"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase"
                     /protein_id="NP_308561.1"
                     /db_xref="GeneID:914638"
                     /translation="MTPAVKSLEKNKISFQIHTYEHDPAETNFGDEVVKKLGLNPDQV
                     YKTLLVAVNGDMKHLAVAVTPVAGQLDLKKVAKALGAKKVEMADPMVAQRSTGYLVGG
                     ISPLGQKKRLPTIIDAPAQEFATIYVSGGKRGLDIELAAGDLAKILDAKFADIARRD"
     misc_feature    complement(572397..572873)
                     /gene="ybaK"
                     /locus_tag="ECs_0534"
                     /note="Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK; Region:
                     PRK10670"
                     /db_xref="CDD:182634"
     misc_feature    complement(order(572487..572489,572568..572573,
                     572736..572738))
                     /gene="ybaK"
                     /locus_tag="ECs_0534"
                     /note="putative deacylase active site [active]"
                     /db_xref="CDD:237976"
     gene            complement(573077..573871)
                     /gene="ybaP"
                     /locus_tag="ECs_0535"
                     /db_xref="GeneID:914639"
     CDS             complement(573077..573871)
                     /gene="ybaP"
                     /locus_tag="ECs_0535"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308562.1"
                     /db_xref="GeneID:914639"
                     /translation="MDLLYRVKTLWAALRGNHYTWPAIDISLPGNRHFHLIGSIHMGS
                     HDMAPLPTRLLKKLKNADALIVEADVSTSDTPFANLPACEALEERISEEQLQKLQHIS
                     QEMGISPSLFSTQPLWQIAMVLQATQAQKLGLRAEYGIDYQLLQAAKQQHKPVIELEG
                     AENQIAMLLQLPDKGLALLDDTLTHWHTNARLLQQMMSWWLNAPPQNNEITLPNTFSQ
                     SLYDVLMHQRNLAWRDKLRAMPPGRYVVAVGALHLYGEGNLPQMLR"
     misc_feature    complement(573080..573871)
                     /gene="ybaP"
                     /locus_tag="ECs_0535"
                     /note="Uncharacterized conserved protein YbaP, TraB family
                     [Function unknown]; Region: TraB; COG3735"
                     /db_xref="CDD:226258"
     gene            573955..574350
                     /gene="ybaQ"
                     /locus_tag="ECs_0536"
                     /db_xref="GeneID:914640"
     CDS             573955..574350
                     /gene="ybaQ"
                     /locus_tag="ECs_0536"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_308563.3"
                     /db_xref="GeneID:914640"
                     /translation="MIQYVLVSLFTGKQQLKTMKQATRKPTTPGDILLYEYLEPLDLK
                     INELAELLHVHRNSVSALINNNRKLTTEMAFRLAKVFDTTVDFWLNLQAAVDLWEVEN
                     NMRTQEELGRIETVAEYLARREERAKKVA"
     misc_feature    574012..574317
                     /gene="ybaQ"
                     /locus_tag="ECs_0536"
                     /note="Plasmid maintenance system antidote protein VapI,
                     contains XRE-type HTH domain [Defense mechanisms]; Region:
                     VapI; COG3093"
                     /db_xref="CDD:225635"
     gene            complement(574565..577069)
                     /gene="copA"
                     /locus_tag="ECs_0537"
                     /db_xref="GeneID:914641"
     CDS             complement(574565..577069)
                     /gene="copA"
                     /locus_tag="ECs_0537"
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="NP_308564.1"
                     /db_xref="GeneID:914641"
                     /translation="MSQTIDLTLDGLSCGHCVKRVKESLEQRPDVEQADVSITEAHVT
                     GTASAEQLIETIKQAGYDASVSHPKAKPLAESSIPSEALTAVSEALPAATADDDDSQQ
                     LLLSGMSCASCVTRVQNALQSVPGVTQARVNLAERTALVMGSASPQDLVQAVEKAGYG
                     AEAIEDDAKRRERQQETAVATMKRFRWQAIVALAVGIPVMVWGMIGDNMMVTADNRSL
                     WLVIGLITLAVMVFAGGHFYRSAWKSLLNGAATMDTLVALGTGVAWLYSMSVNLWPQW
                     FPMEARHLYYEASAMIIGLINLGHMLEARARQRSSKALEKLLDLTPPTARLVTDEGEK
                     SVPLAEVQPGMLLRLTTGDRVPVDGEITQGEAWLDEAMLTGEPIPQQKGEGDSVHAGT
                     VVQDGSVLFRASAVGSHTTLSRIIRMVRQAQSSKPEIGQLADKISAVFVPVVVVIALV
                     SAAIWYFFGPAPQIVYTLVIATTVLIIACPCALGLATPMSIISGVGRAAEFGVLVRDA
                     DALQRASTLDTVVFDKTGTLTEGKPQVVAVKTFADFDEAQALRLAAALEQGSSHPLAR
                     AILDKASDMQLPQVNGFRTLRGLGVSGEAEGHALLLGNQALLNDQQVDTKAIEADISA
                     QASQGATPVLLAVDGKAVALLAVRDPLRSDSVAALQRLHKAGYRLVMLTGDNPTTANA
                     IAKEAGIDEVIAGVLPDGKAEAIKRLQSEGRQVAMVGDGINDAPALAQADVGIAMGGG
                     SDVAIETAAITLMRHSLMGVADALAISRATLRNMKQNLLGAFIYNSIGIPVAAGILWP
                     FTGTLLNPVVAGAAMALSSITVVSNANRLLRFKPKE"
     misc_feature    complement(574568..577069)
                     /gene="copA"
                     /locus_tag="ECs_0537"
                     /note="copper-exporting P-type ATPase CopA; Region: copA;
                     PRK10671"
                     /db_xref="CDD:182635"
     gene            577331..578263
                     /gene="glsA"
                     /locus_tag="ECs_0538"
                     /db_xref="GeneID:914642"
     CDS             577331..578263
                     /gene="glsA"
                     /locus_tag="ECs_0538"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase 1"
                     /protein_id="NP_308565.1"
                     /db_xref="GeneID:914642"
                     /translation="MLDANKLQQAVDQAYTQFHSLNGGQNADYIPFLANVPGQLAAVA
                     IVTSDGNVYSAGDSDYRFALESISKVCTLALALEDVGPQAVQDKIGADPTGLPFNSVI
                     ALELHGGKPLSPLVNAGAIATTSLINAENAEQRWQRILHIQQQLAGELVALSDEVNQS
                     EQTTNFHNRAIAWLLYSAGYLYCDAMEACDVYTRQCSTLINTVELATLGATLAAGGVN
                     PLTHKRVLQADNVPYILAEMMMEGLYGRSGDWAYRVGLPGKSGVGGGILAVVPGVMGI
                     AAFSPPLDEEGNSVRGQKMVASVAKQLGYNVFKG"
     misc_feature    577331..578260
                     /gene="glsA"
                     /locus_tag="ECs_0538"
                     /note="glutaminase; Reviewed; Region: PRK12356"
                     /db_xref="CDD:237073"
     gene            578266..579558
                     /gene="ybaT"
                     /locus_tag="ECs_0539"
                     /db_xref="GeneID:914643"
     CDS             578266..579558
                     /gene="ybaT"
                     /locus_tag="ECs_0539"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid transporter"
                     /protein_id="NP_308566.1"
                     /db_xref="GeneID:914643"
                     /translation="MMNTEGNNGNKPLGLWNVVSIGIGAMVGAGIFALLGQAALLMEA
                     STWVAFAFGGIVAMFSGYAYARLGASYPSNGGIIDFFRRGLGNGVFSLALSLLYLLTL
                     AVSIAMVARAFGAYAVQFLHEGSQEEHLILLYALGIIAVMTLFNSLSNHAVGRLEVIL
                     VGIKMMILLLLIIAGVWSLQPAHISVSAPPSSGAFFSCIGITFLAYAGFGMMANAADK
                     VKDPQVIMPRAFLVAIGVTTLLYISLALVLLSDVSALELEKYADTAVAQAASPLLGHV
                     GYVIVVIGALLATASAINANLFAVFNIMDNMGSERELPKRMNKSLWRQSTWGNIIVVV
                     LIMLMTAALNLGSLASVASATFLICYLAVFVVAIRLRHDIHASLPILIVGTLVMLLVI
                     VGFIYSLWSQGSRALIWIIGAILLSLIVAMVMKRNKTV"
     misc_feature    578266..579537
                     /gene="ybaT"
                     /locus_tag="ECs_0539"
                     /note="Amino acid transporter [Amino acid transport and
                     metabolism]; Region: PotE; COG0531"
                     /db_xref="CDD:223605"
     gene            579896..581251
                     /locus_tag="ECs_0540"
                     /db_xref="GeneID:914644"
     CDS             579896..581251
                     /locus_tag="ECs_0540"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane transport protein"
                     /protein_id="NP_308567.1"
                     /db_xref="GeneID:914644"
                     /translation="MARFQFKNRKNNGLIFFISFMVMGEAAIAAPLPQWANAPAVTPV
                     AQLSLQESILRAFARNPGVTQQAAQIGIGEAQIDEAKSAWYPHVGLTGNAGPSRQTDS
                     SGRLDNNVSYGITLTQLVYDFGKTNNDINLQTAARDSYRFKLMATLTDVAEKTATAYM
                     EVSRYQALCDAAQRNIHSLENVYNMAALRANAGLNSSSDELQAQTRIAGMRSTLEQYQ
                     AQMASAKAQLAVLTGVQPEAIAAPPAELAEQPVSLKNIDYQSIPLVLAAENLRQSAQY
                     GVEKTKAQYWPTLSIQGGKTRYQTSDRSYWDDQLQLNVNAPLYQGGAVSAQVQQAEGQ
                     QKISASQVEQAKLDVLQRASVAYANWTGARGREEAGLAQSESAHKTRDVYQNEYKLGK
                     RSLNDLLTVEQDVFQAQSAEINANYDGWVAAVNYAAAVNNLIPLAGIKQGLYNDLPDL
                     K"
     misc_feature    580028..581233
                     /locus_tag="ECs_0540"
                     /note="type I secretion outer membrane protein, TolC
                     family; Region: type_I_sec_TolC; TIGR01844"
                     /db_xref="CDD:273829"
     gene            581354..585739
                     /locus_tag="ECs_0541"
                     /db_xref="GeneID:914888"
     CDS             581354..585739
                     /locus_tag="ECs_0541"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308568.1"
                     /db_xref="GeneID:914888"
                     /translation="MSLIIDVISRKTSVKQTLINPGDVTVVIYEPSVVQVHAQASAVA
                     RYVREGNDLLIYMQDGTVIRCNGYFLQAANTAEQSELVFADGQQLTHITFADTAAGGL
                     APVELTAQTTAIESIAPFLDTVAQTSAFPWGWLAGAAVGGGALGALLASGGDGDSKTE
                     VINNPTPPAEPGNATPSFLVTDNQGDQRGILATNDITDDTTPTFSGSGQAGATIQIKD
                     SNGNTIASTQVDNNGHWSVSLPTQSAGEHTWSVVQIVGSTITDAGSITLTIDNSQASV
                     QVATTAGDNIINASEQAAGFTLSGTSSHLAQGTELTVTLNGKTYTTSVGANGAWSVQV
                     PTADAQALGEGNQAVLVSGKDATGNTVTGAQLLTVDTQPPTLAINTIAQDNIISAAEH
                     NVALVLSGTSNAEAGQTVTLTVNGKSHTATVGSDGTWQVTLPATEVQALAEGNYAVNA
                     SVSDRAGNTTSHSANFTVDTSAPVVSVNTVAGDDILNNAEQAVAQIISGQVSGASPGD
                     TVTVKLGTHVLTGIVLADGSWNVALDPAVTRTLDRGANTIFVTVTDAAGNTGAASRAI
                     TLVGVSPLITINTVSGDDIISGAEKGAPLTLTGSTQQAETGQTVTVTLAGQSFTTTVQ
                     ADGSWSLTVPAAAMGNLPDGAVAITASVTDLSGNTGNTSRTITVDSQAPALSIDPLTA
                     DNIINAAESGQDLPITGTTDAQPGQTVTVTLNGQTYQGVVQPDGTWSVTVPAANVGAL
                     ADGNATVTASVNDVAGNPSSVSRVALVDATPPVVTINPVATDNVINTPEHAQAQIISG
                     TVTGAQAGDIVTVTLNNVDYTTVVDGSGNWSLGVPASVVSGLADGSYPVSVSVTDKAG
                     NTGSQSLTVTVNTAAPLIGINSIAGDDVINASEKGADLQITGTSDQPVNTAITVTLNG
                     QNYTTTTDASGNWSVTVPASAVTALGQANYTVTAAVTSDIGNSATASHNVLVDSALPG
                     VTINPVATDDIINAAEAGVAQTISGQVTGAEDGDTVTITLGGNTYTATVGSNLTWSVD
                     VPAADIQALGNGDLTVNASVTNQNGNTGSGTRDITIDANLPGLRVDTVAGDDVVNIIE
                     HGQALVVTGSSSGLAESTPLTVTINNVEYTTAVQADGSWSVGVTAAQVSAWPAGTVNI
                     AVSGESSAGNSVSITHPVTVDLTPAAITINTIATDDVINAAEKGADLTLSGTTTNVEP
                     GQTVTVTFGGKNYTASVASDGSWTATVPAADLASLPEGSASALASVSNINGNSASAVH
                     NYSVDSSAPTIIINTVASDNIVNASEADAGVTVSGSTTAEAGQIVTITLNSPTVQTYQ
                     ATVQADGSWSINIPAADLEALTDGSHTLTATVNDKAGNPASTTHNLAVDLTVPVLTIN
                     TIAGDDIINATEHGQALVISGSSTGGEAGDVVTVTLNSKTYTTTLDASGNWSVGVPAA
                     DVTALGSGPQTVTATVTDAAGNSDN"
     misc_feature    581366..581560
                     /locus_tag="ECs_0541"
                     /note="BapA prefix-like domain; Region: biofilm_BapA_N;
                     NF033677"
                     /db_xref="CDD:411274"
     misc_feature    581918..582163
                     /locus_tag="ECs_0541"
                     /note="Bacterial Ig-like domain; Region: Big_13;
                     pfam19077"
                     /db_xref="CDD:408847"
     misc_feature    582143..582436
                     /locus_tag="ECs_0541"
                     /note="Ca2+-stabilized adhesin repeat; Region:
                     Ca_tandemer; NF033510"
                     /db_xref="CDD:411149"
     misc_feature    582452..582733
                     /locus_tag="ECs_0541"
                     /note="Ca2+-stabilized adhesin repeat; Region:
                     Ca_tandemer; NF033510"
                     /db_xref="CDD:411149"
     misc_feature    582740..583033
                     /locus_tag="ECs_0541"
                     /note="Ca2+-stabilized adhesin repeat; Region:
                     Ca_tandemer; NF033510"
                     /db_xref="CDD:411149"
     misc_feature    583040..583333
                     /locus_tag="ECs_0541"
                     /note="Ca2+-stabilized adhesin repeat; Region:
                     Ca_tandemer; NF033510"
                     /db_xref="CDD:411149"
     misc_feature    583340..583630
                     /locus_tag="ECs_0541"
                     /note="Ca2+-stabilized adhesin repeat; Region:
                     Ca_tandemer; NF033510"
                     /db_xref="CDD:411149"
     misc_feature    583637..583930
                     /locus_tag="ECs_0541"
                     /note="Ca2+-stabilized adhesin repeat; Region:
                     Ca_tandemer; NF033510"
                     /db_xref="CDD:411149"
     misc_feature    583937..584227
                     /locus_tag="ECs_0541"
                     /note="Ca2+-stabilized adhesin repeat; Region:
                     Ca_tandemer; NF033510"
                     /db_xref="CDD:411149"
     misc_feature    584234..584527
                     /locus_tag="ECs_0541"
                     /note="Ca2+-stabilized adhesin repeat; Region:
                     Ca_tandemer; NF033510"
                     /db_xref="CDD:411149"
     misc_feature    584534..584827
                     /locus_tag="ECs_0541"
                     /note="Ca2+-stabilized adhesin repeat; Region:
                     Ca_tandemer; NF033510"
                     /db_xref="CDD:411149"
     misc_feature    584834..585127
                     /locus_tag="ECs_0541"
                     /note="Ca2+-stabilized adhesin repeat; Region:
                     Ca_tandemer; NF033510"
                     /db_xref="CDD:411149"
     misc_feature    585137..585433
                     /locus_tag="ECs_0541"
                     /note="Ca2+-stabilized adhesin repeat; Region:
                     Ca_tandemer; NF033510"
                     /db_xref="CDD:411149"
     misc_feature    585440..585733
                     /locus_tag="ECs_0541"
                     /note="Ca2+-stabilized adhesin repeat; Region:
                     Ca_tandemer; NF033510"
                     /db_xref="CDD:411149"
     gene            585947..601822
                     /locus_tag="ECs_0542"
                     /db_xref="GeneID:914929"
     CDS             585947..601822
                     /locus_tag="ECs_0542"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308569.1"
                     /db_xref="GeneID:914929"
                     /translation="MPASAVGALGEASYTVTANVTDSAGNSNSASHNVQVNTALPGVT
                     INPVATDDIINAAESGNAQTISGQVTGAAAGDTVTVTLGGKTYTATVQGNLSWSVDVP
                     AADIQAIGNGNLTVNASVTNGVGNTGSGSRDITIDANLPGLRVDTVAGDDVVNSIEHA
                     QALVITGSSSGLAAGAALTVVINTVTYAATVLADGTWSVGVPAADVSNWPAGTVNITV
                     SGTNTAGTTSTITHPVTVDLAAVAISINTVSGDDVINAAEKGADLTLSGSTSGVEVGQ
                     TVTVTFGGKTYTATVAGDGSWTTTVPAADLSVLRDGDATVQASVSTINGNTASATHAY
                     SVDATAPTLAINTIATDDILNAAEAGNPLTISGSSTAEAGQTVTVTLNGVTYSGSVQA
                     DGSWSVSLPTADLSNLTASQYTVSASVSDKAGNPASANHGLAVDLTVPVLTINTVSGD
                     DIINAAEHGQALVISGSSTGGEAGDVITVTLNSKTYTTMLDASGNWSVGVPAADVTAL
                     GSGPQTITAAITDAAGNSDDASRTVTVNLAAPTIGINTIATDDVIKATEKGADLQITG
                     TSNQPAGTTITVTLNGQNYTATTDSNGNWSATVPASAVSALGEANYTVTANVTDTAGN
                     SNSASHNVLVNSALPAVTINAVATDDIINAAESGNAQTISGQVTGAAQGDTVTVTLGG
                     NTYTATVQSNLSWSVDVPAADIQALGNGDLTVNASVTNGVGNTGSGSRDITIDANLPG
                     LRVDTVAGDDVINSIEHNQALVITGSSSGLTAGTALTVEINNVTYGATVLADGTWSLG
                     VPAVDVSNWPAGTVNITVSGTNSAGTTSTITHPVTVDLAGVAITINTLSGDDVINAVE
                     KGETLVVSGSTSGVEAGQTVTVTFGGKNYTTTVEANGSWTVNVPPADLAALPDGAGNV
                     QASVSNINGNSAQADRAYSVDATAPLVTINTIASDDILNVSEAGAGITISGTTTAQAG
                     QTLTVTLNNNTYQTTVLADGTWSVNVPAADLSGLTASSYTVTATVSDKAGNPASADHA
                     LVVDITAPDLTINTVAGDDIINAIEHGQALVVSGTSTGAAAGDVVTVTLNGKNYTTTL
                     DASGNWSVGIPAADVTALATGSQTITASLSDRAGNSDSTTHDVTVDLSGPTLTINTVS
                     GDDIINAAEIVVAQTISGQVTGTAVAGNTVIVTIGGNQYNATVQSDLSWSVSVPANVL
                     QALGNGELTISASLTNSANNTGTATHDIVIDANLPGLRVDTVAGDDVINSIEHTQALV
                     ITGSSSGLAAGAALTVVINSVTYGATVLADGSWSVGVPVADVTNWPAGTVNIAVSGTN
                     TAGTTTSISHPVTVDLAAVAITINTLSTDDVINAAEKGSDLQLSGTTSGVEAGQTITV
                     IFGGKSYTTTVAADNTWGLTIPAVDVATLPDGAANVQASVSNVAGNSTQATHAYSVDA
                     TAPSVTINTIATDDILNAAEAGSALTISGTSTAEAGQTVTVTLNGVNYSGNVQADGSW
                     SVSVPTGDLASLTASSYTVNASVSDKARNSASATHNLTVDLAAPVVTINTVAGDDIIN
                     ATEHGQAQIISGSATGATTGNTVSVTIGTTTYTTVLDANGNWSIGVPASVISALAQGD
                     VTITATVTDSAGNSGTASHTVTVALGAPVLAINTIAVDDIINAAEKGADLAITGTSNQ
                     PAGTQITVTLNGQNYTTTADASGNWSVTVPASRVSALGEATYTVTAAATDADGNSGSA
                     SHNVQVNTALPGVTINVVATDDIINAAEAGVEQTISGQVTGAAAGDTVTVTLGGATYT
                     ATVQANLSWSVDVPASALQELGNGELTISASVTNSVGNTGNGTREITIDANLPGLRVD
                     TVAGDDVVNIIEHGQALVITGSSSGLAAGSNVTLTINGQTYVAAVLADGTWSVGVPAV
                     DVSAWPAGSVTIAASGSTSAGNPVSVTHPVTVDLSAVAVSINAITADDVINAAEKGAA
                     LTLSGSTSGVEAGQTVTVTFGGKTYSATVAANGSWSTSVPAADMAALRDGDASAQASV
                     SNVNGNSATTTHAYSVDASAPTVTINTIAGDDILNAAEAGAALTITGSSTAEAGQTVT
                     VTLNGTNYTGTVQTDGSWSVSVPSADLSTLTASNYTVNAAVSDKAGNPASVNHNLTVD
                     TSVPVVTINTVAGDDVINATEHAQAQIISGSATGAATGSTVTVTIGTNTFTTVLDASG
                     NWSVGVPASVVSALANGTVTINASVTDAGGNSGSATHQVTVNTGLPTITFNAISGDNI
                     LNADEKGQPLTISGGSTGLATGAQVTVTLNGHNYSATTDASGNWTLTVPVSDLAALGQ
                     ANYTVSASATSAAGNTASSQANLLVDSGLPDVTINTVAGDDIINAAEAGADQTISGVV
                     TRAAAGDTVTVTLGGNTYTATVQSNLSWSVSVPTADLQALGNGDLTITASVTNANGNT
                     GSGTRDITIDANLPGLRVDTVAGDDIVNSIEHGQALVITGGSSGLNAGAVLTVTINSV
                     AYSATVQADGSWSVGIPAANVSAWPAGPLTVEVDGQSSANNPVSVSHPFTVDLTAVAI
                     SINTVASDDVINAAEKGTNLTLSGSTSGIESGQTVTVTFGGKTYTASVAANGSWSVNV
                     PAADLATLPEGAANVQASVSSASGNSASATHAYSVDASAPTLTINTIASDDILNAAEA
                     GSPLTISGTSTAETGQTVTVTLNGATYTGTVQADGSWSVSVPTSALGALNASNYTVSA
                     TVNDKAGNPGSASHNLAVDTTAPVLTINTVAGDDIINDAEHAQALVISGTSSGGEAGD
                     VVSVVLNGKTYTTTLDASGNWSVGVPAADVTALGSGAQTITASVSDRAGNSDDASRTV
                     TVSLSAPVISINTIAGDDVINATEKGSDLALSGTSDQPAGTAITVTLNGQNYSATTDA
                     SGNWSVTVPASAVSALGEATYSVTASVTNAQGNSSTASHNVQVNTALPGITINPVATD
                     DIINASEAGSAQTISGQVTGAAAGSTVTVELGGKTYTATVQADLSWNVSVPAADWQAL
                     GNGELTVNASVTNAVGNTGSGTRDITIDASLPGLRVDTVAGDDVVNIIEHAQAQVITG
                     SSSGFAAGTALTVVINNQTYAATVLANGSWSVGVPATDVSNWPAGTLNITVSGANSAG
                     TQTSITHPLTVDLTAVAISMNSITSDDAINAAEKGAALTLSGSTSGVEAGQTVTVTFG
                     GKTYTTTVAANGSWSTTVPAADLAALRDGDASAQVRVTNVNGNSATATHEYSVDSAAP
                     TVTINTIASDNIINASEAAAGVTVSGTSTAQTGQTLTVTLNGTNYQTTVQTDGSWSLT
                     LPASDLTALANNGYTLTATVSDLAGNLGSASKGVTVDTTAPVISFNTVAGDDVINNVE
                     HIQAQIISGTATGAVAGDRLVVTIAGQQYVTSTDASGNWSVGVPASVISGLADGTVTI
                     SATITDSAGNSSTQTHNVQVNTAAVSLSVSTISGDNLINAAEAGSALTLSGTGTNFAT
                     GTVVTVLLNGKGYSATIQSNGSWSVNVPAADVAALSDGTSYTVSASAQDSAGNGNSST
                     QTHNVQVNTAAVSLSVSTISGDNLINAAEAGSALTLSGTGTNFATGTVVTVLLNGKGY
                     SATIQSNGSWSVNVPAADVAALSDGTSYTVSASAQDSAGNSATASRSVAVDLTAPVIS
                     INTVSTDDRLNAAEQQQPLTLNGSTSAEVGQTVTVTFGGKTYTATVAANGTWALNVPA
                     VDLAALGQGAQTITASVNDRAGNPGQATHALTVDTVAPTVTIATVAGDDIINNAEQLA
                     GQTISGTTTAEVGQTVTVTFNGQTWSATVGSGGSWSVFIPAQQFAGLSDGSYTISATV
                     SDQAGNPGSASRGVTLNGDVPTVTINTFAGDDVVNAAEHGSSLVISGTTTAPVGQTLT
                     LTLNGKTYTTTVQTGGSWSYTLGSADVTALADGNAYVINASVSNAIGNTGSSNHTITV
                     DLSAPAMGINIDSLQADTGLSASDFITSVSPVVVNGSLTAALASNETAQISIDGGTTW
                     TTLTVTGTTWRYNDSRTLTDGNYLYQVRVIDAAGNVGATDSQNVVIDTTAPDPAVKTI
                     AISAITTDMGLITNDFVTSDTTLAVSGTLGATLSAGEFAQISLDGGVTWTTLTVVGTS
                     WSYADGHTLTDGTWNYTVRVVDLAGNVGQTATQNVVVDTTSPEAAKSITITGISDDTG
                     TSSSDFITSDTTLTVRGVLGAALGANEFAQISTDNGATWVNVTVAADSLNWSYVDGRT
                     LTNGTTTWQVRVVDLAGNVGATSSQSALIDTVNPAQVLTIASISTDTGSSATDFITSD
                     TMLTLTGSLGAGLASGEVAQISLDSGATWTTLTTNGTQWTYTDSRTLTDGSYVYQVRV
                     LDLAGNTGPVVSKTVVVDTINPTATPTIVSYTDDVGQRQGTLSSSQATDDTTPLLNGV
                     LSAPLASGEVVYLYRNGLLLGAVTMVGALNWTYSDSGLVSGAYTYSARVVDLAGNITS
                     SSDFVLTVDTSIPTTLAQITSQTTRDTTPIISGVITAALASGQYVEVVINGKTYTSEP
                     GGAVVVDPAHNTWYVQLPDTDALTVSATAYTVTAQVKSSAGNGNNANISNGTVTVNAA
                     IDYTPTWTTASKTTAWGLTYGLDSHGMWTVLANQQVMQSTDPLTWSKTALTLYQSGNN
                     YATSSIADYDRNGTGDLFITRDDYGTGYINGFTNNGDGTFSSAIQVTVGTLTWYGSIV
                     AFDKEGDGYLDFWIGDAGGPDSNTFLWNNAGTLVGNSTTSNSGGSATVGGAVTGYLSL
                     NEGSGVDLNNDGRIDLVQHTYNLNNYYTLSSLINQGNGTFVWGQNTTNTFLSGAGSGA
                     MSSSVSMTWADFDGDGDMDLFLPASQGRANYGSLLFNTNGVLGCPVAVGATATTYASQ
                     FSLAVDWNHDGLMDIARIAQTGQSYLYTNVSNASNWTQSALGGSQSGTTSGVAAMDYD
                     WDGAVDVLVSKQSGSVFLSRNTNTVSYGTSLHLRITDPNGINVYYGNTVKLYNSAGVL
                     VATQIINPQSGMGVNDTSALVNFYGLNAGETYNAVLIKSTGTTASNIDQTVNTSWGGL
                     QATDATHAYDLSAEAGTASNNGKFVGTGYNDTFFATAGTDTYDGSGGWVYSSGTGTWL
                     ANGGMDVVDFRLSTVGVTANLSSTAAQATGFNTSTFTNIEGISGSNFNDILTGSSGDN
                     QLEGRGGNDTLNIGNGGHDTLLYKLLNASDATGGNGSDVVNGFTVGTWEGTADTDRID
                     IRELLQGSGYTGNGKASYVNGVATLDAQAGNIGDFVKVTQSGSDTIVQIDRDGTGGTF
                     ATTNVVTLTGVHTDLATLLANHQLMVV"
     misc_feature    586004..586270
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    586154..586633
                     /locus_tag="ECs_0542"
                     /note="tandem large repeat; Region: tail_200_repeat;
                     NF032891"
                     /db_xref="CDD:380157"
     misc_feature    586598..586903
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    586925..587167
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    587198..587497
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    587504..587755
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    587798..588091
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    587969..588427
                     /locus_tag="ECs_0542"
                     /note="tandem large repeat; Region: tail_200_repeat;
                     NF032891"
                     /db_xref="CDD:380157"
     misc_feature    588392..588697
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    588671..588958
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    588992..589294
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    589301..589564
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    589601..589855
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    589892..590197
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    590195..590461
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    590516..590794
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    590792..591046
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    591119..591358
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    591389..591649
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    591701..591991
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    592013..592252
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    592295..592588
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    592586..592855
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    592886..593155
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    593060..593506
                     /locus_tag="ECs_0542"
                     /note="tandem large repeat; Region: tail_200_repeat;
                     NF032891"
                     /db_xref="CDD:380157"
     misc_feature    593483..593752
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    593822..594046
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    594083..594385
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    594383..594640
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    594680..594940
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    594980..595249
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    595277..595549
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    595577..595840
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    595877..596179
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    596177..596437
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    596480..596746
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    596789..597055
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    597086..597385
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    597383..597673
                     /locus_tag="ECs_0542"
                     /note="Ig-like domain; Region: Ig_like_ice; NF012196"
                     /db_xref="CDD:380150"
     misc_feature    597785..598054
                     /locus_tag="ECs_0542"
                     /note="Bacterial Ig-like domain; Region: Big_13;
                     pfam19077"
                     /db_xref="CDD:436945"
     misc_feature    598106..598375
                     /locus_tag="ECs_0542"
                     /note="Bacterial Ig-like domain; Region: Big_13;
                     pfam19077"
                     /db_xref="CDD:436945"
     misc_feature    598418..598699
                     /locus_tag="ECs_0542"
                     /note="Bacterial Ig-like domain; Region: Big_13;
                     pfam19077"
                     /db_xref="CDD:436945"
     misc_feature    598736..599011
                     /locus_tag="ECs_0542"
                     /note="Bacterial Ig-like domain; Region: Big_13;
                     pfam19077"
                     /db_xref="CDD:436945"
     misc_feature    <598898..599326
                     /locus_tag="ECs_0542"
                     /note="Ig-like repeat protein Blp2; Region: Ig_like_BLP2;
                     NF040520"
                     /db_xref="CDD:439735"
     misc_feature    599846..600034
                     /locus_tag="ECs_0542"
                     /note="Repeat domain in Vibrio, Colwellia, Bradyrhizobium
                     and Shewanella; Region: VCBS; pfam13517"
                     /db_xref="CDD:433275"
     misc_feature    600191..600412
                     /locus_tag="ECs_0542"
                     /note="Repeat domain in Vibrio, Colwellia, Bradyrhizobium
                     and Shewanella; Region: VCBS; pfam13517"
                     /db_xref="CDD:433275"
     misc_feature    600536..600721
                     /locus_tag="ECs_0542"
                     /note="Repeat domain in Vibrio, Colwellia, Bradyrhizobium
                     and Shewanella; Region: VCBS; pfam13517"
                     /db_xref="CDD:433275"
     misc_feature    601346..601453
                     /locus_tag="ECs_0542"
                     /note="Haemolysin-type calcium-binding repeat (2 copies);
                     Region: HemolysinCabind; pfam00353"
                     /db_xref="CDD:425631"
     misc_feature    601541..601810
                     /locus_tag="ECs_0542"
                     /note="type I secretion C-terminal target domain (VC_A0849
                     subclass); Region: T1SS_VCA0849; TIGR03661"
                     /db_xref="CDD:274707"
     gene            601826..603988
                     /gene="lapB"
                     /locus_tag="ECs_0543"
                     /db_xref="GeneID:915052"
     CDS             601826..603988
                     /gene="lapB"
                     /locus_tag="ECs_0543"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_308570.2"
                     /db_xref="GeneID:915052"
                     /translation="MKKNAQSVEAWLEAMIAVARYYRLDFSQENVRATVNWERDSKRE
                     ELLTDMARQLGMGLRLVEFSADSLNPWRLPLIAVFDNQQIGVITRRDNHDNISVQFSG
                     DEGLETTLNVADIEDKIVELALLRPLSAIPDARVDDYIRPYQANWFWSLSLKDWRRYG
                     DIMLASLVANVLALAAMIFSMQVYDRVVPAQSYPTLWVLFAGVMMAILFEFCMRMVRT
                     HLSDVIGKRADLRISDRVFGHALRLKNNVRSKSTGSFISQIRELESVRELITSTTIGA
                     VADLPFFLLFVFILWMIGGWLVLVVLLALPLLVIPGLLVQRPLARLANEGMRESAVRN
                     ATLVEAVQSIEDIKLLRAEQRFQNQWNHTNDVASSISMKQRFLTGLLLTWTQEVQSIV
                     YVVVLLVGCFMVMNGDMTTGALVGTTILASRTIAPLSQISGVLSRWQQAKVARNGLDE
                     LMKRPVDQPEHGKLVHKAVLHGNYQFSNAVFYYDEEEKIADVAIGKLNIQAGEKIAIL
                     GRNGAGKSTLLQMLAGMRIAQQGQVLLDNISIGQLDPADLRRDMGLLSQTGRLFFGSL
                     RENLTMGMPEASDEDIERALTLSGALPFVQKQKNGLNYMIQEGGFGLSGGQRQTLLLA
                     RLLISQPNIVLLDEPSASLDEMAEAYLIEQLKQWIGHRTLIIATHRTAMLQLVDRIIV
                     MDQGRIVMDGAKEAILREQGEPTARRVVLQEKNKGSAA"
     misc_feature    601856..603937
                     /gene="lapB"
                     /locus_tag="ECs_0543"
                     /note="type I secretion system ATPase, LssB family;
                     Region: type_I_sec_LssB; TIGR03375"
                     /db_xref="CDD:274550"
     gene            603985..605160
                     /locus_tag="ECs_0544"
                     /db_xref="GeneID:915176"
     CDS             603985..605160
                     /locus_tag="ECs_0544"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane fusion protein of a transport system"
                     /protein_id="NP_308571.1"
                     /db_xref="GeneID:915176"
                     /translation="MNGQLQYNRGLTEPRLPRSALAVRVTAVMLLCFLGWAWYFQLDE
                     VTTGSGTVEPSGREQVVQSLEGGILYHLDVKVGDIVEQGQPLAQLNRTKTESDVQEAM
                     SRLYAALATSARLRAEVSNKPLVFPDELNKFPELIESETALYNTRRDGLNKATTGLTQ
                     GISLVNRELAMTQPLVKQGAASSVEVLRLQRQANELENKLSDVRTQYYVQAREELAKA
                     NAEVETQRSVIRGREDSLTRLNFTAPVRGIVQDIDVTTVGGVIAPGGKLMTIVPLDEQ
                     LLIEAKISPRDVAFIHPGQKSLVKITAYDYSIYGGLPGEVAVISPDTVQDEVRRDVYY
                     YRVYIRTFSNHLENKSKQQFPIFPGMVATVDIRTGKKSVLDYLLKPFNKAQEALRER"
     misc_feature    604024..605157
                     /locus_tag="ECs_0544"
                     /note="type I secretion membrane fusion protein, HlyD
                     family; Region: type_I_hlyD; TIGR01843"
                     /db_xref="CDD:130902"
     gene            605157..605564
                     /gene="cueR"
                     /locus_tag="ECs_0545"
                     /db_xref="GeneID:915192"
     CDS             605157..605564
                     /gene="cueR"
                     /locus_tag="ECs_0545"
                     /codon_start=1
                     /transl_table=11
                     /product="copper-responsive regulon transcriptional
                     regulator"
                     /protein_id="NP_308572.1"
                     /db_xref="GeneID:915192"
                     /translation="MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHL
                     NELTLLRQARQVGFNLEESGELVNLFNDPQRHSADVKRRTLEKVAEIERHIEELQSMR
                     NQLLALANACPGDDSADCPIIENLSGCCHHRAG"
     misc_feature    605157..605561
                     /gene="cueR"
                     /locus_tag="ECs_0545"
                     /note="HTH-type transcriptional regulator CueR; Region:
                     PRK10227"
                     /db_xref="CDD:182320"
     gene            complement(605768..606190)
                     /locus_tag="ECs_0546"
                     /db_xref="GeneID:915251"
     CDS             complement(605768..606190)
                     /locus_tag="ECs_0546"
                     /codon_start=1
                     /transl_table=11
                     /product="putative lipoprotein"
                     /protein_id="NP_308573.1"
                     /db_xref="GeneID:915251"
                     /translation="MMNSSIKSFSLLAVILLAGCSSPTSRIADCQAQGVSHDTCYLAE
                     QQRQAAILSASEAQAFKNAEAAQHAQAAKKAIYKGFGMTFRMSSKNFAYLNDSLCAID
                     EDNKDATVYQSGLYNVIVYHHTGKVALMKEGQFVGYLK"
     gene            complement(606275..607291)
                     /locus_tag="ECs_0548"
                     /db_xref="GeneID:915314"
     CDS             complement(606275..607291)
                     /locus_tag="ECs_0548"
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="NP_308575.1"
                     /db_xref="GeneID:915314"
                     /translation="MKTVNVALLALIISATSSPVVLAGDTIEAAATELSAINSGMSQS
                     EIEQKITRFLERTDNSPAAYTYLTEHHYIPSETPDTTQTPTVQTDPDAGQKTVAATGD
                     VQTTARYQSMINARQSAVTDAQQTQITEQQAQIVATQKTLAATGDTQNTAHYQEMINA
                     RLAAQNEANQRTATEQGQKMNALTTDVAVQQQNERTQYDKQMQSLAQESAQAHEQIDS
                     LSQDVTQTHQQLTNTQKRVADNSQQINTLNNHFSSLKNEVDDNRKEANAGTASAIAIA
                     SQPQVKTGDVMMVSAGAGTFNGESAVSVGTSFNAGTHTVLKAGISADTQSDFGAGVGV
                     GYSF"
     misc_feature    complement(<606278..607291)
                     /locus_tag="ECs_0548"
                     /note="Autotransporter adhesin [Intracellular trafficking,
                     secretion, and vesicular transport, Extracellular
                     structures]; Region: Hia; COG5295"
                     /db_xref="CDD:227614"
     gene            607658..608020
                     /locus_tag="ECs_0549"
                     /db_xref="GeneID:915335"
     CDS             607658..608020
                     /locus_tag="ECs_0549"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308576.1"
                     /db_xref="GeneID:915335"
                     /translation="MNEFEKIFNEMNLDRALLPILFRSNRSTVWKYLSGDSTAPASAM
                     SLIMLLQLIQKRNPDLLAEWLTLSDFTIPPEVYLDQPDYWKGWVYTQHKVNKNVLEYL
                     KKHYPDEDQKSMSKGREE"
     gene            complement(608199..608657)
                     /gene="ybbJ"
                     /locus_tag="ECs_0551"
                     /db_xref="GeneID:915339"
     CDS             complement(608199..608657)
                     /gene="ybbJ"
                     /locus_tag="ECs_0551"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein"
                     /protein_id="NP_308578.2"
                     /db_xref="GeneID:915339"
                     /translation="MMELIVVHPHIFWLSLGGLLLAAEMLGGNGYLLWSGVAAVITGL
                     VVWLVPLGWEWQGVMFAVLTLLAAWLWWKWLSRRVREQKHSDSHLNQRGQQLIGRRFV
                     LESPLVNGRGHMRVGDSSWPVSASEDLGAGTHVEVIAIEGITLIIRAVIA"
     misc_feature    complement(608208..608636)
                     /gene="ybbJ"
                     /locus_tag="ECs_0551"
                     /note="Membrane protein implicated in regulation of
                     membrane protease activity [Posttranslational
                     modification, protein turnover, chaperones]; Region: YbbJ;
                     COG1585"
                     /db_xref="CDD:224501"
     gene            complement(608654..609571)
                     /gene="qmcA"
                     /locus_tag="ECs_0552"
                     /db_xref="GeneID:915340"
     CDS             complement(608654..609571)
                     /gene="qmcA"
                     /locus_tag="ECs_0552"
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="NP_308579.1"
                     /db_xref="GeneID:915340"
                     /translation="MLIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPG
                     LSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNANVTIDAVCFIQVIDAPRAAYEVS
                     NLELAIINLTMTNIRTVLGSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIR
                     DVRPPAELISSMNAQMKAERTKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSA
                     FLQAEARERSAEAEARATKMVSEAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVM
                     MPLEASSLMGSIAGIAELVKDSANKRTQP"
     misc_feature    complement(608693..609571)
                     /gene="qmcA"
                     /locus_tag="ECs_0552"
                     /note="Regulator of protease activity HflC,
                     stomatin/prohibitin superfamily [Posttranslational
                     modification, protein turnover, chaperones]; Region: HflC;
                     COG0330"
                     /db_xref="CDD:223407"
     gene            609717..610394
                     /gene="fetA"
                     /locus_tag="ECs_0553"
                     /db_xref="GeneID:915342"
     CDS             609717..610394
                     /gene="fetA"
                     /locus_tag="ECs_0553"
                     /codon_start=1
                     /transl_table=11
                     /product="iron export ABC transporter ATPase"
                     /protein_id="NP_308580.1"
                     /db_xref="GeneID:915342"
                     /translation="MQENSPLLQLQNVGYLAGDAKILNNINFSLRAGEFKLITGPSGC
                     GKSTLLKIVASLISPTSGTLLFEGEDVSTLKPEIYRQQVSYCAQTPTLFGDTVYDNLI
                     FPWQIRNQQPDPAIFLDFLERFALPDSILTKNIAELSGGEKQRISLIRNLQFMPKVLL
                     LDEITSALDESNKHNVNEMIHRYVREQNIAVLWVTHDKDEINHADKVITLQPHAGEMQ
                     EARYELA"
     misc_feature    609717..610391
                     /gene="fetA"
                     /locus_tag="ECs_0553"
                     /note="putative ABC transporter ATP-binding protein YbbL;
                     Provisional; Region: PRK10247"
                     /db_xref="CDD:182331"
     gene            610381..611160
                     /gene="fetB"
                     /locus_tag="ECs_0554"
                     /db_xref="GeneID:915343"
     CDS             610381..611160
                     /gene="fetB"
                     /locus_tag="ECs_0554"
                     /codon_start=1
                     /transl_table=11
                     /product="iron export ABC transporter permease"
                     /protein_id="NP_308581.2"
                     /db_xref="GeneID:915343"
                     /translation="MNSHNITNESLALALMLVVVAILISHKEKLALEKDILWSVGRAI
                     IQLIIVGYVLKYIFSVDDASLTLLMVLFICFNAAWNAQKRSKYIAKAFISSFIAITVG
                     AGITLAVLILSGSIEFIPMQVIPIAGMIAGNAMVAVGLCYNNLGQRVISEQQQIQEKL
                     SLGATPKQASAILIRDSIRAALIPTVDSAKTVGLVSLPGMMSGLIFAGIDPVKAIKYQ
                     IMVTFMLLSTASLSTIIACYLTYRKFYNSRHQLVVTQLKKK"
     misc_feature    610396..611133
                     /gene="fetB"
                     /locus_tag="ECs_0554"
                     /note="TIGR00245 family protein; Region: TIGR00245"
                     /db_xref="CDD:272982"
     gene            complement(611223..612077)
                     /gene="ybbN"
                     /locus_tag="ECs_0555"
                     /db_xref="GeneID:915346"
     CDS             complement(611223..612077)
                     /gene="ybbN"
                     /locus_tag="ECs_0555"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="NP_308582.2"
                     /db_xref="GeneID:915346"
                     /translation="MSVENIVNINESNLQQVLEQSMTTPVLFYFWSERSQHCLQLTPI
                     LESLAAQYNGQFILAKLDCDAEQMIAAQFGLRAIPTVYLFQNGQPVDGFQGPQPEEAI
                     RALLDKVLPREEELKAQQAMQLMQEGNYTDALPLLKDAWQLSNQNGEIGLLLAETLIA
                     LNRSEDAEAVLKTIPLQDQDTRYQGLVAQIELLKQAADTPEIQQLQQQVAENPEDAAL
                     ATQLALQLHQVGRNEEALELLFGHLRKDLTAADGQTRKTFQEILAALGTGDALASKYR
                     RQLYALLY"
     misc_feature    complement(611226..612077)
                     /gene="ybbN"
                     /locus_tag="ECs_0555"
                     /note="Negative regulator of GroEL, contains
                     thioredoxin-like and TPR-like domains [Posttranslational
                     modification, protein turnover, chaperones]; Region: YbbN;
                     COG3118"
                     /db_xref="CDD:225660"
     misc_feature    complement(611649..611738)
                     /gene="ybbN"
                     /locus_tag="ECs_0555"
                     /note="TPR repeat [structural motif]; Region: TPR repeat"
                     /db_xref="CDD:276808"
     misc_feature    complement(611553..611636)
                     /gene="ybbN"
                     /locus_tag="ECs_0555"
                     /note="TPR repeat [structural motif]; Region: TPR repeat"
                     /db_xref="CDD:276808"
     misc_feature    complement(611340..611435)
                     /gene="ybbN"
                     /locus_tag="ECs_0555"
                     /note="TPR repeat [structural motif]; Region: TPR repeat"
                     /db_xref="CDD:276808"
     misc_feature    complement(611229..611327)
                     /gene="ybbN"
                     /locus_tag="ECs_0555"
                     /note="TPR repeat [structural motif]; Region: TPR repeat"
                     /db_xref="CDD:276808"
     gene            complement(612138..612947)
                     /gene="ybbO"
                     /locus_tag="ECs_0556"
                     /db_xref="GeneID:915348"
     CDS             complement(612138..612947)
                     /gene="ybbO"
                     /locus_tag="ECs_0556"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="NP_308583.1"
                     /db_xref="GeneID:915348"
                     /translation="MTHKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLA
                     GCRKPDDVERMNSMGFTGVLIDLDSPESVDRAADEVIALTDNCLYGIFNNAGFGMYGP
                     LSTISRAQMEQQFSANFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYA
                     ASKYALEAWSDALRMELRRSGIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARF
                     TLGPEAVVDKVRHAFISEKPKMRYPVTLVTWAVMVLKRLLPGRVMDKILQG"
     misc_feature    complement(612141..612908)
                     /gene="ybbO"
                     /locus_tag="ECs_0556"
                     /note="SDR family oxidoreductase; Region: PRK08017"
                     /db_xref="CDD:181198"
     gene            complement(612937..613530)
                     /gene="tesA"
                     /locus_tag="ECs_0557"
                     /db_xref="GeneID:915351"
     CDS             complement(612937..613530)
                     /gene="tesA"
                     /locus_tag="ECs_0557"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase I"
                     /protein_id="NP_308585.2"
                     /db_xref="GeneID:915351"
                     /translation="MPFLFLVLLTFRAAAADTLLILGDSLSAGYRMSASAAWPALLND
                     KWQSKTSVVNASISGDTSQQGLARLPALLKQHQPRWVLVELGGNDGLRGFQPQQTEQT
                     LRQILQDVKAANAEPLLMQIRLPANYGRRYNEAFSAIYPKLAKEFDVPLLPFLMEEVY
                     LKPQWMQDDGIHPNRDAQPFIADWMAKQLQPLVNHDS"
     misc_feature    complement(612940..613512)
                     /gene="tesA"
                     /locus_tag="ECs_0557"
                     /note="multifunctional acyl-CoA thioesterase I and
                     protease I and lysophospholipase L1; Provisional; Region:
                     PRK10528"
                     /db_xref="CDD:182521"
     misc_feature    complement(order(613015..613017,613024..613026,
                     613267..613269,613354..613356,613456..613458))
                     /gene="tesA"
                     /locus_tag="ECs_0557"
                     /note="active site"
                     /db_xref="CDD:238860"
     misc_feature    complement(order(613015..613017,613024..613026,
                     613456..613458))
                     /gene="tesA"
                     /locus_tag="ECs_0557"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:238860"
     misc_feature    complement(order(613267..613269,613354..613356,
                     613456..613458))
                     /gene="tesA"
                     /locus_tag="ECs_0557"
                     /note="oxyanion hole [active]"
                     /db_xref="CDD:238860"
     misc_feature    complement(613246..613263)
                     /gene="tesA"
                     /locus_tag="ECs_0557"
                     /note="switch loop [active]"
                     /db_xref="CDD:238860"
     gene            613531..614217
                     /gene="ybbA"
                     /locus_tag="ECs_0558"
                     /db_xref="GeneID:915350"
     CDS             613531..614217
                     /gene="ybbA"
                     /locus_tag="ECs_0558"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATPase"
                     /protein_id="NP_308584.2"
                     /db_xref="GeneID:915350"
                     /translation="MPAENIVEVHHLKKSVGQGEHELSILTGVELVVKRGETIALVGE
                     SGSGKSTLLAILAGLDDGSSGEVSLVGQPLHNMDEEARAKLRAKHVGFVFQSFMLIPT
                     LNALENVELPALLRGESSAESRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARA
                     FNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLIMVTHDLQLAARCDRCLR
                     LVNGQLQEEA"
     misc_feature    613531..614214
                     /gene="ybbA"
                     /locus_tag="ECs_0558"
                     /note="putative ABC transporter ATP-binding protein YbbA;
                     Provisional; Region: PRK10584"
                     /db_xref="CDD:182569"
     misc_feature    613657..613680
                     /gene="ybbA"
                     /locus_tag="ECs_0558"
                     /note="Walker A/P-loop; other site"
                     /db_xref="CDD:213222"
     misc_feature    order(613666..613671,613675..613683,613813..613815,
                     614041..614046,614143..614145)
                     /gene="ybbA"
                     /locus_tag="ECs_0558"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:213222"
     misc_feature    613804..613815
                     /gene="ybbA"
                     /locus_tag="ECs_0558"
                     /note="Q-loop/lid; other site"
                     /db_xref="CDD:213222"
     misc_feature    613969..613998
                     /gene="ybbA"
                     /locus_tag="ECs_0558"
                     /note="ABC transporter signature motif; other site"
                     /db_xref="CDD:213222"
     misc_feature    614029..614046
                     /gene="ybbA"
                     /locus_tag="ECs_0558"
                     /note="Walker B; other site"
                     /db_xref="CDD:213222"
     misc_feature    614053..614064
                     /gene="ybbA"
                     /locus_tag="ECs_0558"
                     /note="D-loop; other site"
                     /db_xref="CDD:213222"
     misc_feature    614131..614151
                     /gene="ybbA"
                     /locus_tag="ECs_0558"
                     /note="H-loop/switch region; other site"
                     /db_xref="CDD:213222"
     gene            614214..616628
                     /gene="ybbP"
                     /locus_tag="ECs_0559"
                     /db_xref="GeneID:915353"
     CDS             614214..616628
                     /gene="ybbP"
                     /locus_tag="ECs_0559"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="NP_308586.1"
                     /db_xref="GeneID:915353"
                     /translation="MIARWFWREWRSPSLLIVWLALSLAVACVLALGNISDRMEKGLS
                     QQSREFMAGDRALRSSREVPQAWLEEAQKRGLKVGKQLTFATMTFAGDTPQLANVKAV
                     DDIYPMYGDLQTNPPGLKPQAGSVLLAPRLMALLNLKTGDTIDVGDATLRIAGEVIQE
                     PDSGFNPFQMAPRLMMNLADVDKTGAVQPGSRVTWRYKFGGSENQLDSYEKWLLPQLK
                     PEQRWYGLEQDEGALGRSMERSQQFLLLSALLTLLLAVAAVAVAMNHYCRSRYDLVAI
                     LKTLGAGRAQLRKLIVGQWLMVLTLSAVTGGAIGLLFENVLMVLLKPVLPAALPPASL
                     WPWLWALGTMTVISLLVGLRPYRLLLATQPLRVLRNYVVANVWPLKFYLPIVSVVVVL
                     LLAGLMGGSMLLWAVLAGAVVLALLCGVLGWMLLNVLRRMTLKSLPLRLAVSRLLRQP
                     WSTLSQLSAFSLSFMLLALLLVLRGDLLDRWQQQLPPESPNYFLINIATEQVTPLKAF
                     LAEHQIVPESFYPVVRARLTAINGKPTEGNEDEALNRELNLTWQNTRPDHNPIVAGNW
                     PPKADEVSMEEGLAKRLNVTLGDTVTFMGDTQEFRAKVTSLRKVDWESLRPNFYFIFP
                     EGALDGQPQSWLTSFRWENGNGMLTQLNRQFPTISLLDIGAILKQVGQVLEQVSRALE
                     VMVVLVTACGMLLLLAQVQVGMRQRHQELVVWRTLGAGKKLLRTTLWCEFAMLGFVSG
                     LVAAIGAETALAVLQAKVFDFPWEPDWRLWIVLPCSGALLLSLFGGWLGARLVKGKAL
                     FRQFAG"
     misc_feature    614214..616619
                     /gene="ybbP"
                     /locus_tag="ECs_0559"
                     /note="Predicted ABC-type transport system involved in
                     lysophospholipase L1 biosynthesis, permease component
                     [Secondary metabolites biosynthesis, transport and
                     catabolism]; Region: YbbP; COG3127"
                     /db_xref="CDD:225669"
     gene            617058..621254
                     /gene="rhsD"
                     /locus_tag="ECs_0560"
                     /db_xref="GeneID:915354"
     CDS             617058..621254
                     /gene="rhsD"
                     /locus_tag="ECs_0560"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion protein Rhs"
                     /protein_id="NP_308587.2"
                     /db_xref="GeneID:915354"
                     /translation="MSGKPAARQGDMTQYGGPIVQGSAGVRIGAPTGVACSVCPGGMT
                     SGNPVNPLLGAKVLPGETDLALPGPLPFILSRTYSSYRTRTPAPVGIFGPGWKAPSDI
                     RLQLRDDALVLNDNGGRSIHFEPLLPGEAVYSRSESMWLVRGGKAAQPDGHTLARLWG
                     ALPPDIRLSPHLYLATNSAQGPWWILGWSERVPGAEDVLPAPLPPYRVLTGMADRFGR
                     TLTYRREAAGDLAGEITGVTDGAGREFRLVLTTQAQRAEEARKQHTASLSSPDTPRPL
                     SDSAFPDTLPGTEYGPDRGIRLSAVWLTHDPAYPESLPAAPLVRYTYTEAGELLAVYD
                     RSNTQVRAFTYDAQHPGRMVGHRYAGRPEMRYRYDDAGRVVEQLNPAGLSYHYQYEQD
                     RITVTDSLNRREVLHTEGGAGLKRVVKKELADGSVTHSGYDAAGRLTAQTDAAGRRTE
                     YGLNVVSGDITDITTPDGRETKFYYNDGNQLTAVVSPDGLESRRAYDEPGRLVSETSR
                     SGETVRYRYDDAYSELPATTTDATGSTRQMTWSRYGQLLAFTDCSGYQTRYEYDRFGQ
                     MTAVHREEGISLYRRYDNRGRLISVKDAQGHETRYEYNAAGDLTAVITPDGNRSETQY
                     DAWGKAVSTTQGGLTRSMEYDLAGRITTLTNENGSRSEFTYDALDRLVQQRGFDGRTQ
                     RYHYDLTGKLTQSEDEGLVTLWHYDESDRLTHRTVNGEPAEQWQYDEHGWLTEISHLS
                     EGHQVAVHYGYDDKGRLAGERQTVHNPETGELLWQHETEHAYNEQGLANRVTPDSLPR
                     VEWLTYGSGYLAGMKLGGTPLVEFTRDRLHRETVRSFGNNAYELTSTYTPAGHLQSQR
                     LNSQVYDRDYDWNDNGDLVRISGPRQTREYGYSATGRLESVRTLASDLDIRIPYATDP
                     AGNRLPDPELHPDSTLTAWPDNRIAEDAHYVYRHDEYGRLTEKTDRIPAGVIRTDDER
                     THHYHYDSQHRLVFYTRIQHGEPLVESRYLYDPLGRRTGKRVWRRGRDLTGWMSLSRK
                     PEVTWYGWDGDRLTTVQTDTTRIQTVYEPGSFAPLIRIETDNGEREKAQRRSLAEKLQ
                     QEGSEDGHGVVFPAELVRLLDRLEEEIRADRVSSESRAWLAQCGLTVEQLARQVEPEY
                     TPARKVHLYHCDHRGLPLALISEDGNTAWSGEYDEWGNQLNEENPHHLHQPYRLPGQQ
                     YDKESGLYYNRNRYYDPLQGRYITQDPIGLEGGWSLYAYPLNPVNGIDPLGLSPADVA
                     LIRRKDQLNHQRAWDILSDTYEDMKRLNLGGTDQFFHCMAFCRVSKLNDAGVSRSAKG
                     LGYEKEIRDYGLNLFGMYGRKVKLSHSEMIEDNKKDLAVNDHGLTCPSTTDCSDRCSD
                     YINPEHKETIKALQDAGYLK"
     misc_feature    <617058..617144
                     /gene="rhsD"
                     /locus_tag="ECs_0560"
                     /note="proline-alanine-alanine-arginine (PAAR) repeat
                     superfamily; Region: PAAR_like; cl21497"
                     /db_xref="CDD:451275"
     misc_feature    617193..617426
                     /gene="rhsD"
                     /locus_tag="ECs_0560"
                     /note="Domain of unknown function (DUF6531); Region:
                     DUF6531; pfam20148"
                     /db_xref="CDD:437980"
     misc_feature    <617673..619100
                     /gene="rhsD"
                     /locus_tag="ECs_0560"
                     /note="Uncharacterized conserved protein RhsA, contains 28
                     RHS repeats [General function prediction only]; Region:
                     RhsA; COG3209"
                     /db_xref="CDD:225750"
     misc_feature    618684..621191
                     /gene="rhsD"
                     /locus_tag="ECs_0560"
                     /note="Uncharacterized conserved protein RhsA, contains 28
                     RHS repeats [General function prediction only]; Region:
                     RhsA; COG3209"
                     /db_xref="CDD:225750"
     gene            621235..621495
                     /gene="ybbD"
                     /locus_tag="ECs_0561"
                     /db_xref="GeneID:915355"
     CDS             621235..621495
                     /gene="ybbD"
                     /locus_tag="ECs_0561"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308588.1"
                     /db_xref="GeneID:915355"
                     /translation="MLAISSNLSKMIIFIIAIIIIVVLCVITYLYLYKDESLVSKHYI
                     NYMAIPENDGVFTWLPDFFPHVAVDISIYTNVEDDYFFLIFP"
     misc_feature    621235..621489
                     /gene="ybbD"
                     /locus_tag="ECs_0561"
                     /note="hypothetical protein; Provisional; Region:
                     PRK14710"
                     /db_xref="CDD:173173"
     gene            complement(622239..622610)
                     /gene="ylbG"
                     /locus_tag="ECs_0563"
                     /db_xref="GeneID:915360"
     CDS             complement(622239..622610)
                     /gene="ylbG"
                     /locus_tag="ECs_0563"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_308590.2"
                     /db_xref="GeneID:915360"
                     /translation="MLHTANPVIKHKAGLLNLAEELSNVSKACKIMGVSRDTFYRYRE
                     LVAEGGVDAQINRSRRAPNLKNRTDEATEQAVVDYAVAFPTHGQHRASNELRKQGVFI
                     SDSGVRSVWLLHNLENLKRRY"
     misc_feature    complement(<622245..622580)
                     /gene="ylbG"
                     /locus_tag="ECs_0563"
                     /note="IS481 family transposase; Region: transpos_IS481;
                     NF033577"
                     /db_xref="CDD:411202"
     gene            complement(622726..623820)
                     /gene="mnmH"
                     /locus_tag="ECs_0564"
                     /db_xref="GeneID:915481"
     CDS             complement(622726..623820)
                     /gene="mnmH"
                     /locus_tag="ECs_0564"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine synthase"
                     /protein_id="NP_308591.1"
                     /db_xref="GeneID:915481"
                     /translation="MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMN
                     NDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQ
                     RSHIVQSWLHAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQ
                     QQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDES
                     RMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQ
                     EYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYD
                     PMYRYQLEKKAEKVVFRGEWAEVAEWVKAQ"
     misc_feature    complement(622729..623814)
                     /gene="mnmH"
                     /locus_tag="ECs_0564"
                     /note="tRNA 2-selenouridine synthase; Provisional; Region:
                     PRK11784"
                     /db_xref="CDD:236982"
     gene            complement(623889..624815)
                     /gene="allS"
                     /locus_tag="ECs_0565"
                     /db_xref="GeneID:915486"
     CDS             complement(623889..624815)
                     /gene="allS"
                     /locus_tag="ECs_0565"
                     /codon_start=1
                     /transl_table=11
                     /product="allD operon transcriptional activator"
                     /protein_id="NP_308592.1"
                     /db_xref="GeneID:915486"
                     /translation="MFDPETLRTFIAVAETGSFSKAAERLCKTTATISYRIKLLEENT
                     GVALFFRTTRSVTLTAAGEHLLSQARDWLSWLESMPSELQQVNDGVERQVNIVINNLL
                     YNPQAVAQLLAWLNERYPFTQFHISRQIYMGVWDSLLYEGFSLAIGVTGTEALANTFS
                     LDPLGSVQWRFVMAADHPLANVEEPLTEAQLRRFPAVNIEDSARTLTKRVAWRLPGQK
                     EIIVPDMETKIAAHLAGVGIGFLPKSLCQSMIDNQQLVSRVIPTMRPPSPLSLAWRKF
                     GSGKAVEDIVTLFTQRRPEISGFLEIFGNPRS"
     misc_feature    complement(623892..624815)
                     /gene="allS"
                     /locus_tag="ECs_0565"
                     /note="HTH-type transcriptional activator AllS; Region:
                     PRK10094"
                     /db_xref="CDD:182237"
     gene            625045..625527
                     /gene="allA"
                     /locus_tag="ECs_0566"
                     /db_xref="GeneID:915530"
     CDS             625045..625527
                     /gene="allA"
                     /locus_tag="ECs_0566"
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate hydrolase"
                     /protein_id="NP_308593.1"
                     /db_xref="GeneID:915530"
                     /translation="MKLQVLPLSQEAFSAYGDVIETQQRDFFHINNGLVERYHDLALV
                     EILEQDRTLISINRAQPANLPLTIHELERHPLGTQAFIPMKGEVFVVVVALGDDKPDL
                     STLRAFITNGEQGVNYHRNVWHHPLFAWQRVTDFLTIDRGGSDNCDVESIPEQELCFA
                     "
     misc_feature    625045..625524
                     /gene="allA"
                     /locus_tag="ECs_0566"
                     /note="Ureidoglycolate hydrolase (allantoin degradation)
                     [Nucleotide transport and metabolism]; Region: AllA;
                     COG3194"
                     /db_xref="CDD:225735"
     gene            625605..626420
                     /gene="allR"
                     /locus_tag="ECs_0567"
                     /db_xref="GeneID:915706"
     CDS             625605..626420
                     /gene="allR"
                     /locus_tag="ECs_0567"
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate-inducible transcriptional repressor
                     of all and gcl operons"
                     /protein_id="NP_308594.1"
                     /db_xref="GeneID:915706"
                     /translation="MTEVRRRGRPGQAEPVAQKGAQALERGIAILQYLEKSGGSSSVS
                     DISLNLDLPLSTTFRLLKVLQAADFVYQDSQLGWWHIGLGVFNVGAAYIHNRDVLSVA
                     GPFMRRLMLLSGETVNVAIRNGNEAVLIGQLECKSMVRMCAPLGSRLPLHASGAGKAL
                     LYPLAEEELMSIILQTGLQQFTPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCI
                     ASAIYDDVGSVVAAISISGPSSRLTEDRFVSQGELVRDTARDISTALGLKAHP"
     misc_feature    625605..626417
                     /gene="allR"
                     /locus_tag="ECs_0567"
                     /note="HTH-type transcriptional repressor AllR; Region:
                     PRK10163"
                     /db_xref="CDD:182279"
     gene            626510..628291
                     /gene="gcl"
                     /locus_tag="ECs_0568"
                     /db_xref="GeneID:915770"
     CDS             626510..628291
                     /gene="gcl"
                     /locus_tag="ECs_0568"
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate carboligase"
                     /protein_id="NP_308595.1"
                     /db_xref="GeneID:915770"
                     /translation="MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIR
                     HILARHVEGASHMAEGYTRATAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITG
                     QAPRARLHKEDFQAVDIEAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLV
                     DLPFDVQVAEIEFDPDMYEPLPVYKPAASRMQIEKAVEMLIQAERPVIVAGGGVINAD
                     AAALLQQFAELTSVPVIPTLMGWGCIPDDHELMAGMVGLQTAHRYGNATLLASDMVFG
                     IGNRFANRHTGSVEKYTEGRKIVHIDIEPTQIGRVLCPDLGIVSDAKAALTLLVEVAQ
                     EMQKAGRLPCRKEWVADCQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTT
                     IGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPKRNVVAISGDFDFQ
                     FLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFENINSSEVNGYG
                     VDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILERVTNISMGSE
                     LDNVMEFEDIADNAADAPTETCFMHYE"
     misc_feature    626510..628270
                     /gene="gcl"
                     /locus_tag="ECs_0568"
                     /note="glyoxylate carboligase; Provisional; Region:
                     PRK11269"
                     /db_xref="CDD:183066"
     gene            628304..629080
                     /gene="hyi"
                     /locus_tag="ECs_0569"
                     /db_xref="GeneID:915783"
     CDS             628304..629080
                     /gene="hyi"
                     /locus_tag="ECs_0569"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxypyruvate isomerase"
                     /protein_id="NP_308596.1"
                     /db_xref="GeneID:915783"
                     /translation="MLRFSANLSMLFGEYDFLARFEKAAQCGFRGVEFMFPYDYDIEE
                     LKQVLASNKLEHTLHNLPAGDWAAGERGIACIPGREEEFRDGVAAAIRYARALGNKNI
                     NCLVGKTPAGFSSEQIHATLVENLRYAANMLMKEDILLLIEPINHFDIPGFHLTGTRQ
                     ALKLIDDVGCCNLKIQYDIYHMQRMEGELTNTMTQWADKIGHLQIADNPHRGEPGTGE
                     INYDYLFKVIENSDYNGWVGCEYKPQTTTEAGLRWMDPYR"
     misc_feature    628304..629077
                     /gene="hyi"
                     /locus_tag="ECs_0569"
                     /note="hydroxypyruvate isomerase; Provisional; Region:
                     PRK09997"
                     /db_xref="CDD:182188"
     gene            629181..630059
                     /gene="glxR"
                     /locus_tag="ECs_0570"
                     /db_xref="GeneID:915794"
     CDS             629181..630059
                     /gene="glxR"
                     /locus_tag="ECs_0570"
                     /codon_start=1
                     /transl_table=11
                     /product="tartronate semialdehyde reductase"
                     /protein_id="NP_308597.1"
                     /db_xref="GeneID:915794"
                     /translation="MKLGFIGLGIMGTPMAINLARAGHQLHVTTIGPVADELLSLGAV
                     NVDTARQVTEAADIIFIMVPDTPQVEEVLFGENGCTKASLKGKTIVDMSSISPIETKR
                     FARQVNELGGDYLDAPVSGGEIGAREGTLSIMVGGDEAVFERVKPLFELLGKNITLVG
                     GNGDGQTCKVANQIIVALNIEAVSEALLFASKAGADPVRVRQALMGGFASSRILEVHG
                     ERMIKRTFNPGFKIALHQKDLNLALQSAKALALNLPNTATCQELFNTCAANGGSQLDH
                     SALVQALELMANHKLA"
     misc_feature    629181..630056
                     /gene="glxR"
                     /locus_tag="ECs_0570"
                     /note="2-hydroxy-3-oxopropionate reductase; Region:
                     PRK15059"
                     /db_xref="CDD:185019"
     gene            630228..631619
                     /gene="ybbW"
                     /locus_tag="ECs_0572"
                     /db_xref="GeneID:915888"
     CDS             630228..631619
                     /gene="ybbW"
                     /locus_tag="ECs_0572"
                     /codon_start=1
                     /transl_table=11
                     /product="allantoin transporter"
                     /protein_id="NP_308599.1"
                     /db_xref="GeneID:915888"
                     /translation="MEHQRKLFQQRGYSEDLLPKTQSQRTWKTFNYFTLWMGSVHNVP
                     NYVMVGGFFILGLSTFSIMLAIILSAFFIAAVMVLNGAAGSKYGVPFAMILRASYGVR
                     GALFPGLLRGGIAAIMWFGLQCYAGSLACLILIGKIWPGFLTLGGDFTLLGLSLPGLI
                     TFLLFWLVNVGIGFGGGKVLNKFTAILNPCIYIVFGGMAIWAISLVGLGPIFDYIPSG
                     IQKAENSGFLFLVVINAVVAVWAAPAVSASDFTQNAHSFREQALGQTLGLVVAYILFA
                     VAGVCIIAGASIHYGADTWNVLDIVQRWDSLFASFFAVLVILMTTISTNATGNIIPAG
                     YQIAAIAPTKLTYKNGVLIASIISLLICPWKLMENQDSIYLFLDIIGGMLGPVIGVMM
                     AHYFVVMRGQINLDELYTAPGDYKYYDNGFNLTAFSVTLVAVILSLGGKFIPLMEPLS
                     RVSWFVGVIVAFA"
     misc_feature    630228..631616
                     /gene="ybbW"
                     /locus_tag="ECs_0572"
                     /note="putative allantoin permease; Region: PRK11375"
                     /db_xref="CDD:183106"
     misc_feature    order(630339..630341,630348..630350,631185..631187,
                     631194..631199)
                     /gene="ybbW"
                     /locus_tag="ECs_0572"
                     /note="Na binding site [ion binding]; other site"
                     /db_xref="CDD:271378"
     misc_feature    order(630351..630353,630582..630584,630594..630596,
                     630942..630947,630951..630953,631200..631202,
                     631212..631214)
                     /gene="ybbW"
                     /locus_tag="ECs_0572"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:271378"
     gene            631656..633017
                     /gene="allB_1"
                     /locus_tag="ECs_0573"
                     /pseudogene="unknown"
                     /db_xref="GeneID:62676040"
     misc_feature    631656..633017
                     /gene="allB_1"
                     /locus_tag="ECs_0573"
                     /note="allantoinase"
                     /pseudogene="unknown"
     gene            633074..634375
                     /gene="ybbY"
                     /locus_tag="ECs_0575"
                     /db_xref="GeneID:916089"
     CDS             633074..634375
                     /gene="ybbY"
                     /locus_tag="ECs_0575"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil/xanthine transporter"
                     /protein_id="NP_308602.2"
                     /db_xref="GeneID:916089"
                     /translation="MFNFAVSRESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLL
                     TLTQYAFLATALACFAQAFCGHRRAIMEGPGGLWWGTILTITLGEASRGTPINDIATS
                     LAVGIALSGVLTMLIGFSGLGHRLARLFTPSVMVLFMLMLGAQLTTIFFKGMLGLPFG
                     IADPNFKIQLPPFALSVAVMCLVLAMIIFLPQRFARYGLLVGTITGWLLWYFCFPSSH
                     SLSGELHWQWFPLGSGGALSPGIILTAVITGLVNISNTYGAIRGTDVFYPQQGAGNTR
                     YRRSFVATGFMTLITVPLAVIPFSPFVSSIGLLTQTGDYTRRSFIYGSVICLLVALVP
                     ALTRLFCSIPLPVSSAVMLVSYLPLLFSALVFSQQITFTARNIYRLALPLFVGIFLMA
                     LPPVYLQDLPLTLRPLLSNGLLVGILLAVLMDNLIPWERIE"
     misc_feature    633074..634372
                     /gene="ybbY"
                     /locus_tag="ECs_0575"
                     /note="uracil/xanthine transporter; Region: PRK11412"
                     /db_xref="CDD:183124"
     gene            634397..635542
                     /gene="glxK"
                     /locus_tag="ECs_0576"
                     /db_xref="GeneID:916187"
     CDS             634397..635542
                     /gene="glxK"
                     /locus_tag="ECs_0576"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase II"
                     /protein_id="NP_308603.1"
                     /db_xref="GeneID:916187"
                     /translation="MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDANYICLPIADG
                     GEGTVDAMVAATGGNIVTLEVCGPMGEKVNAFYGITGDGKTAVIEMAAASGLMLVAPE
                     KRNPLLASSFGTGELIRHALDNGIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQV
                     LVANGGNLARVASIEMEECDPRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEM
                     VEELEQGLQNYARVLQQQTEINVCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLRAV
                     NLEQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVIGIAGVLGDGVEVVH
                     QYGIDAVFSILPRLAPLAEVLASGETNLFNSARNIACAIKIGQGIKN"
     misc_feature    634397..635539
                     /gene="glxK"
                     /locus_tag="ECs_0576"
                     /note="glycerate 3-kinase; Region: PRK09932"
                     /db_xref="CDD:182152"
     gene            complement(635770..636555)
                     /gene="ylbA"
                     /locus_tag="ECs_0577"
                     /db_xref="GeneID:916390"
     CDS             complement(635770..636555)
                     /gene="ylbA"
                     /locus_tag="ECs_0577"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308604.1"
                     /db_xref="GeneID:916390"
                     /translation="MGYLNNVTGYRDDLLANRAIVKHGNFALLTPDGLVKNIIPGFEN
                     CDATILSTPKLGASFVDYLVTLHQNGGNQQGFGGEGIETFLYVISGNITAKAEGKTFS
                     LSEGGYLYCPPGSLMTFVNAQAEDSQIFLYKRRYVPVEGYAPWLVSGNASELERIHYE
                     GMDDVILLDFLPKELGFDMNMHILSFAPGASHGYIETHVQEHGAYILSGQGVYNLDNN
                     WIPVKKGDYIFMGAYSLQAGYGVGRGEAFSYIYSKDCNRDVEI"
     misc_feature    complement(635773..636555)
                     /gene="ylbA"
                     /locus_tag="ECs_0577"
                     /note="Ureidoglycine aminohydrolase [Nucleotide transport
                     and metabolism]; Region: AllE; COG3257"
                     /db_xref="CDD:225796"
     gene            complement(636566..637801)
                     /gene="allC"
                     /locus_tag="ECs_0578"
                     /db_xref="GeneID:916571"
     CDS             complement(636566..637801)
                     /gene="allC"
                     /locus_tag="ECs_0578"
                     /codon_start=1
                     /transl_table=11
                     /product="allantoate amidohydrolase"
                     /protein_id="NP_308605.1"
                     /db_xref="GeneID:916571"
                     /translation="MITHFRQTIEEALPWLSSFGADPAGGMTRLLYSPEWLETQQQLK
                     KRMAASGLETRFDEVGNLYGRLSGTEYPQEVILSGSHIDTVVNGGNLDGQFGALAARL
                     AIDWLKTQYGAPLRTVEVVAMAEEEGSRFPYVFWGSKNIFGLANPDDVRNICDAKGNS
                     FVDAMKACGFTLPDAPLTPRQDIKAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTV
                     TLNGESNHAGTTPMGYRRDTVYAFSRICHQSIEKAKKMGDPLVLTFGKVEPRPNTVNV
                     VPGKTTFTIDCRHTDAAVLRDFTQQLENDMRAICDEMDIRIDIDLWMDEEPVPMNKDL
                     VATLTELCESEKLNYRVMHSGAGHDAQIFAPRVPTCMIFIPSINGISHNPAERTNITD
                     LAEGVKTLALMLYQLAWQK"
     misc_feature    complement(636569..637801)
                     /gene="allC"
                     /locus_tag="ECs_0578"
                     /note="allantoate amidohydrolase; Region: AllC; TIGR03176"
                     /db_xref="CDD:274471"
     gene            complement(637823..638872)
                     /gene="allD"
                     /locus_tag="ECs_0579"
                     /db_xref="GeneID:916572"
     CDS             complement(637823..638872)
                     /gene="allD"
                     /locus_tag="ECs_0579"
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate dehydrogenase"
                     /protein_id="NP_308606.1"
                     /db_xref="GeneID:916572"
                     /translation="MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSH
                     GAVRVEYYAERISKGGTNREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQ
                     QNGVAVVGISRMGHSGAISYFVQQAARAGLIGISMCQSDPMVVPFGGAEIYYGTNPLA
                     FAAPGEGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGAPTTDPFAVHALL
                     PAAGPKGYGLMMMIDVLSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHVVINPNFFSSS
                     ELFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRQAAVEGIEIVDDIYQYLISD
                     ALYNTSYETKNPFAQ"
     misc_feature    complement(637826..638872)
                     /gene="allD"
                     /locus_tag="ECs_0579"
                     /note="ureidoglycolate dehydrogenase; Provisional; Region:
                     PRK15025"
                     /db_xref="CDD:184985"
     gene            639189..640856
                     /gene="fdrA"
                     /locus_tag="ECs_0580"
                     /db_xref="GeneID:916573"
     CDS             639189..640856
                     /gene="fdrA"
                     /locus_tag="ECs_0580"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding acyl-CoA synthetase"
                     /protein_id="NP_308607.1"
                     /db_xref="GeneID:916573"
                     /translation="MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKA
                     LLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQAL
                     TQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLK
                     TRAREKGLLVMGPDCGTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGE
                     GITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMK
                     ATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIMPASSGFIC
                     GLYTGGTLAAEAAGLLAGHLGVEADDAHHHGMMLDADGHQIIDLGDDFYTVGRPHPMI
                     DPTLRNQLITDLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARSDNQPLYA
                     IATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLL
                     ENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ"
     misc_feature    639189..640853
                     /gene="fdrA"
                     /locus_tag="ECs_0580"
                     /note="membrane protein FdrA; Validated; Region: PRK06091"
                     /db_xref="CDD:180395"
     gene            640866..642125
                     /gene="ylbE"
                     /locus_tag="ECs_0581"
                     /db_xref="GeneID:916600"
     CDS             640866..642125
                     /gene="ylbE"
                     /locus_tag="ECs_0581"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308608.2"
                     /db_xref="GeneID:916600"
                     /translation="MFTSVAQANAAVIEQIRRARPHWLDVQPASSLISELNEGKTLLH
                     AGPPMRWQEMTGPMKGACVGACLFEGWAKDEAQALAILEQGEVNFIPCHHVNAVGPMG
                     GITSASMPMLVVENVTDGNRAYCNLNEGIGKVMRFGAYGEDVLTRHRWMRDVLMPVLS
                     AALGRMERGIDLTAMMAQGITMGDEFHQRNIASSALLMRALAPQIARLDHDKQHIAEV
                     MDFLSVTDQFFLNLAMAYCKAAMDAGAMIRAGSIVTAMTRNGNMFGIRVSGLGERWFT
                     APVNTPQGLFFTGFSQEQANPDMGDSAITETFGIGGAAMIAAPGVTRFVGASGMEAAR
                     AVSEEMAEIYLERNMQLQIPSWDFQGACLGLDIRRVVETGITPLINTGIAHKEAGIGQ
                     IGAGTVRAPLACFEQALEALAESMGIG"
     misc_feature    641124..641771
                     /gene="ylbE"
                     /locus_tag="ECs_0581"
                     /note="Protein of unknown function (DUF1116); Region:
                     DUF1116; pfam06545"
                     /db_xref="CDD:428999"
     gene            642136..642951
                     /gene="ylbF"
                     /locus_tag="ECs_0582"
                     /db_xref="GeneID:916659"
     CDS             642136..642951
                     /gene="ylbF"
                     /locus_tag="ECs_0582"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic allantoin catabolic oxamate
                     carbamoyltransferase"
                     /protein_id="NP_308609.1"
                     /db_xref="GeneID:916659"
                     /translation="MTIIHPLLASSSAPNYRQSWRLAGVWRRAINLMTESGELLTLHR
                     QGSGFGPGGWVLRRAQFDALCGGLCGNERPQVVAQGIRLGRFTVKQPQRYCLLRITPP
                     AHPQPLAAAWMQRAEETGLFGPLALAASDPLPAELRQFRHCFQAALNGVKTDWRHWLG
                     KGPGLTPSHDDTLSGMLLAAWYYGALDARSGRPFFACSDNLQLVTTAVSVSYLRYAAQ
                     GYFASPLLHFVHALSCPKRTAVAIDSLLALGHTSGADTLLGFWLGQQLLQGKP"
     misc_feature    642607..642927
                     /gene="ylbF"
                     /locus_tag="ECs_0582"
                     /note="Protein of unknown function (DUF2877); Region:
                     DUF2877; pfam11392"
                     /db_xref="CDD:402828"
     gene            642948..643841
                     /gene="ybcF"
                     /locus_tag="ECs_0583"
                     /db_xref="GeneID:916781"
     CDS             642948..643841
                     /gene="ybcF"
                     /locus_tag="ECs_0583"
                     /codon_start=1
                     /transl_table=11
                     /product="carbonate kinase"
                     /protein_id="NP_308610.1"
                     /db_xref="GeneID:916781"
                     /translation="MKTLVVALGGNALLQRGEALTAENQYRNIASAVPALARLARSYR
                     LAIVHGNGPQVGLLALQNLAWKEVEPYPLDVLVAESQGMIGYMLAQSLSAQPQMPPVT
                     TVRTRIEVSPDDPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQP
                     RKILDSEAIELLLKEGHVVICSGGGGVPVTDDGAGSEAVIDKDLAAALLAEQINADGL
                     VILTDADAVYENWGMPQQRAIRHATPDELAPFAKADGSMGPKVTAVSGYVRSRGKPAW
                     IGALSRIEETLAGEAGTCISL"
     misc_feature    642948..643838
                     /gene="ybcF"
                     /locus_tag="ECs_0583"
                     /note="carbamate kinase; Reviewed; Region: PRK09411"
                     /db_xref="CDD:181831"
     misc_feature    order(642966..642968,642972..642977,643095..643103,
                     643311..643313,643548..643556)
                     /gene="ybcF"
                     /locus_tag="ECs_0583"
                     /note="putative substrate binding site [chemical binding];
                     other site"
                     /db_xref="CDD:239768"
     misc_feature    order(642975..642977,643611..643616,643629..643631,
                     643638..643640,643713..643718,643725..643727)
                     /gene="ybcF"
                     /locus_tag="ECs_0583"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239768"
     misc_feature    order(642975..642977,643611..643616,643629..643631,
                     643638..643640,643713..643718,643725..643727)
                     /gene="ybcF"
                     /locus_tag="ECs_0583"
                     /note="nucleotide binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239768"
     misc_feature    order(643125..643127,643158..643160,643167..643172,
                     643179..643181,643191..643196,643203..643205,
                     643212..643217,643227..643229,643254..643262,
                     643266..643268,643440..643442,643449..643451,
                     643530..643532)
                     /gene="ybcF"
                     /locus_tag="ECs_0583"
                     /note="homodimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:239768"
     gene            complement(643980..645047)
                     /gene="purK"
                     /locus_tag="ECs_0584"
                     /db_xref="GeneID:916809"
     CDS             complement(643980..645047)
                     /gene="purK"
                     /locus_tag="ECs_0584"
                     /codon_start=1
                     /transl_table=11
                     /product="N5-carboxyaminoimidazole ribonucleotide
                     synthase"
                     /protein_id="NP_308611.1"
                     /db_xref="GeneID:916809"
                     /translation="MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPAAVPFQQS
                     VITAEIERWPETALTRELARHPAFVNRDVFPIIADRLTQKQLFDKLHLPTAPWQLLAE
                     RSEWPAVFERLGELAIVKRRTGGYDGRGQWRLRADETEQLPAECYGECIVEQGINFSG
                     EVSLVGARCFDGSTVFYPLTHNLHQDGILRTSVAFPQANAQQQAQAEEMLSAIMQELG
                     YVGVMAMECFVTPQGLLINELAPRVHNSGHWTQNGASISQFELHLRAITDLPLPQPVV
                     NNPSVMINLIGSDVNYDWLKLPLVHLHWYDKEVRPGRKVGHLNLTDSDTSRLSATLEA
                     LIPLLPPEYASGVMWAQSKFC"
     misc_feature    complement(643998..645047)
                     /gene="purK"
                     /locus_tag="ECs_0584"
                     /note="Phosphoribosylaminoimidazole carboxylase (NCAIR
                     synthetase) [Nucleotide transport and metabolism]; Region:
                     PurK; COG0026"
                     /db_xref="CDD:223105"
     gene            complement(645044..645553)
                     /gene="purE"
                     /locus_tag="ECs_0585"
                     /db_xref="GeneID:916940"
     CDS             complement(645044..645553)
                     /gene="purE"
                     /locus_tag="ECs_0585"
                     /codon_start=1
                     /transl_table=11
                     /product="N5-carboxyaminoimidazole ribonucleotide mutase"
                     /protein_id="NP_308612.1"
                     /db_xref="GeneID:916940"
                     /translation="MSSRNNPARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSA
                     HRTPDKLFSFAESAEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVD
                     SLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRKAQTDEVL
                     ENPDPRGAA"
     misc_feature    complement(645047..645538)
                     /gene="purE"
                     /locus_tag="ECs_0585"
                     /note="Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
                     [Nucleotide transport and metabolism]; Region: PurE;
                     COG0041"
                     /db_xref="CDD:223119"
     gene            complement(645671..646393)
                     /gene="lpxH"
                     /locus_tag="ECs_0586"
                     /db_xref="GeneID:916941"
     CDS             complement(645671..646393)
                     /gene="lpxH"
                     /locus_tag="ECs_0586"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-2,3-diacylglucosamine pyrophosphohydrolase"
                     /protein_id="NP_308613.1"
                     /db_xref="GeneID:916941"
                     /translation="MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFE
                     AWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKV
                     LELYGRRVLIMHGDTLCTDDAGYQAFRTKVHKPWLQTLFLALPLFVRKRIAVRMRANS
                     KEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGA
                     WHTEGSMVKVTADDVELIHFPF"
     misc_feature    complement(645674..646393)
                     /gene="lpxH"
                     /locus_tag="ECs_0586"
                     /note="UDP-2,3-diacylglucosamine hydrolase; Provisional;
                     Region: PRK05340"
                     /db_xref="CDD:235420"
     misc_feature    complement(order(645803..645805,645809..645811,
                     646052..646054,646154..646159,646271..646273,
                     646364..646366,646370..646372))
                     /gene="lpxH"
                     /locus_tag="ECs_0586"
                     /note="putative active site [active]"
                     /db_xref="CDD:277343"
     misc_feature    complement(order(645803..645805,645809..645811,
                     646052..646054,646157..646159,646271..646273,
                     646364..646366,646370..646372))
                     /gene="lpxH"
                     /locus_tag="ECs_0586"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:277343"
     gene            complement(646396..646890)
                     /gene="ppiB"
                     /locus_tag="ECs_0587"
                     /db_xref="GeneID:916942"
     CDS             complement(646396..646890)
                     /gene="ppiB"
                     /locus_tag="ECs_0587"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase B"
                     /protein_id="NP_308614.1"
                     /db_xref="GeneID:916942"
                     /translation="MVTFHTNHGDIVIKTFDDKAPETVKNFLDYCREGFYNNTIFHRV
                     INGFMIQGGGFEPGMKQKATKEPIKNEANNGLKNTRGTLAMARTQAPHSATAQFFINV
                     VDNDFLNFSGESLQGWGYCVFAEVVEGMDVVDKIKGVATGRSGMHQDVPKEDVIIESV
                     TVSE"
     misc_feature    complement(646399..646890)
                     /gene="ppiB"
                     /locus_tag="ECs_0587"
                     /note="peptidylprolyl isomerase B; Region: PRK10791"
                     /db_xref="CDD:182734"
     misc_feature    complement(order(646531..646533,646567..646572,
                     646594..646596,646618..646635,646738..646740,
                     646744..646749,646756..646758,646762..646764))
                     /gene="ppiB"
                     /locus_tag="ECs_0587"
                     /note="substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:238901"
     gene            647064..648449
                     /gene="cysS"
                     /locus_tag="ECs_0588"
                     /db_xref="GeneID:916943"
     CDS             647064..648449
                     /gene="cysS"
                     /locus_tag="ECs_0588"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteinyl-tRNA synthetase"
                     /protein_id="NP_308615.1"
                     /db_xref="GeneID:916943"
                     /translation="MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTF
                     VAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHKDFDA
                     LNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDL
                     DQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLG
                     NHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFT
                     VRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAG
                     GEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKVEDMAAANAMASHLRKLSAVLG
                     LLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLE
                     DGPQGTTWRRK"
     misc_feature    647064..648446
                     /gene="cysS"
                     /locus_tag="ECs_0588"
                     /note="Cysteinyl-tRNA synthetase [Translation, ribosomal
                     structure and biogenesis]; Region: CysS; COG0215"
                     /db_xref="CDD:223293"
     gene            complement(648485..649006)
                     /gene="ybcI"
                     /locus_tag="ECs_0589"
                     /db_xref="GeneID:916944"
     CDS             complement(648485..649006)
                     /gene="ybcI"
                     /locus_tag="ECs_0589"
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein"
                     /protein_id="NP_308616.1"
                     /db_xref="GeneID:916944"
                     /translation="MPTVITHAAVPLCIGLGLGSKVIPPRLLFAGIILAMLPDADVLS
                     FNFGVAYGNVFGHRGFTHSLVFAFVVPLLCVLIGRRWFRAGLIRCWLFLTVSLLSHSL
                     LDSVTTGGKGVGWLWPWSDERFFAPWQVIKVAPFALSRYTTAYGHQVIISELMWVWLP
                     GMLLMGMLWWRRR"
     misc_feature    complement(648491..649003)
                     /gene="ybcI"
                     /locus_tag="ECs_0589"
                     /note="Membrane-bound metal-dependent hydrolase YbcI,
                     DUF457 family [General function prediction only]; Region:
                     YbcI; COG1988"
                     /db_xref="CDD:224899"
     gene            complement(649114..649326)
                     /gene="ybcJ"
                     /locus_tag="ECs_0590"
                     /db_xref="GeneID:916945"
     CDS             complement(649114..649326)
                     /gene="ybcJ"
                     /locus_tag="ECs_0590"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated protein"
                     /protein_id="NP_308617.2"
                     /db_xref="GeneID:916945"
                     /translation="MATFSLGKHPHVELCDLLKLEGWSESGAQAKIAIAEGQVKVDGA
                     VETRKRCKIVAGQTVSFAGHSVQVVA"
     misc_feature    complement(649117..649326)
                     /gene="ybcJ"
                     /locus_tag="ECs_0590"
                     /note="ribosome-associated protein YbcJ; Region: PRK11507"
                     /db_xref="CDD:183166"
     misc_feature    complement(order(649165..649167,649171..649194,
                     649213..649215,649219..649224,649231..649236,
                     649240..649245,649249..649251))
                     /gene="ybcJ"
                     /locus_tag="ECs_0590"
                     /note="RNA binding surface [nucleotide binding]; other
                     site"
                     /db_xref="CDD:238095"
     gene            complement(649328..650194)
                     /gene="folD"
                     /locus_tag="ECs_0591"
                     /db_xref="GeneID:916946"
     CDS             complement(649328..650194)
                     /gene="folD"
                     /locus_tag="ECs_0591"
                     /codon_start=1
                     /transl_table=11
                     /product="5,10-methylene-tetrahydrofolate dehydrogenase"
                     /protein_id="NP_308618.1"
                     /db_xref="GeneID:916946"
                     /translation="MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSN
                     PASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDALNADNTIDGILVQLPLP
                     AGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGL
                     NAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPG
                     DWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTL
                     QACVEYHDPQGE"
     misc_feature    complement(649340..650194)
                     /gene="folD"
                     /locus_tag="ECs_0591"
                     /note="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase
                     FolD; Region: PRK10792"
                     /db_xref="CDD:236760"
     gene            650665..651207
                     /gene="sfmA"
                     /locus_tag="ECs_0592"
                     /db_xref="GeneID:916947"
     CDS             650665..651207
                     /gene="sfmA"
                     /locus_tag="ECs_0592"
                     /codon_start=1
                     /transl_table=11
                     /product="type-1 fimbrial protein subunit A"
                     /protein_id="NP_308619.2"
                     /db_xref="GeneID:916947"
                     /translation="MKLRFISSALAAALFAATGSYAAVVDGGTIHFEGELVNAACSVN
                     TDSADQVVTLGQYRTDIFNAVGNTSALIPFTIQLNDCDPVVAANAAVAFSGQADAIND
                     NLLAIASSTNTTTATGVGIEILDNTSAILKPDGNSFSTNQNLIPGTNVLHFSARYKGT
                     GTSASAGQANADATFIMRYE"
     misc_feature    650665..651204
                     /gene="sfmA"
                     /locus_tag="ECs_0592"
                     /note="type 1 fimbrial protein subunit FimA; Region:
                     PRK15194"
                     /db_xref="CDD:237920"
     gene            651427..652119
                     /gene="sfmC"
                     /locus_tag="ECs_0593"
                     /db_xref="GeneID:916948"
     CDS             651427..652119
                     /gene="sfmC"
                     /locus_tag="ECs_0593"
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic pilus chaperone"
                     /protein_id="NP_308620.1"
                     /db_xref="GeneID:916948"
                     /translation="MMTKIKLLMLIIFYLIISASVHAAGGIALGATRIIYPADAKQTA
                     VWIRNSHTNERFLVNSWIENSSGVKEKSFIITPPLFVSEPKSENTLRIIYTGPPLAAD
                     RESLFWMNVKTIPSVDKNALNGRNVLQLAILSRMKLFLRPIQLQELPAEAPDTLKFSR
                     SGNYINVHNPSPFYVTLVNLQVGSQKLGNAMAAPRVNSQIPLPSGVQGKLKFQTVNDY
                     GSVTPVREVNLN"
     misc_feature    651427..652113
                     /gene="sfmC"
                     /locus_tag="ECs_0593"
                     /note="molecular chaperone FimC; Region: PRK15195"
                     /db_xref="CDD:185117"
     gene            652150..654759
                     /gene="fimD"
                     /locus_tag="ECs_0594"
                     /db_xref="GeneID:916950"
     CDS             652150..654759
                     /gene="fimD"
                     /locus_tag="ECs_0594"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane usher protein FimD"
                     /protein_id="NP_308621.1"
                     /db_xref="GeneID:916950"
                     /translation="MKIPTTTDIPQRYTWCLAGICYSSLAILPSFLSYAESYFNPAFL
                     LENGTFVADLSRFERGNHQPAGVYRVDLWRNDEFIGSQDIVFESTTENTGDKSGGLMP
                     CFNQVLLERIGLNSSAFPELAQQQNNKCINLLKAVPDATINFDFAAMRLNITIPQIAL
                     LSSAHGYIPPEEWDEGIPALLLNYNFTGNRGNGNDSYFFSELSGINIGPWRLRNNGSW
                     NYFRGNGYHSEQWNNIGTWVQRAIIPLKSELVMGDGNTGSDIFDGVGFRGVRLYSSDN
                     MYPDSQQGFAPTVRGIARTAAQLTIRQNGFIIYQSYVSPGAFEITDLHPTSSNGDLDV
                     TIDERDGNQQNYTIPYSTVPILQREGRFKFDLTAGDFRSGNSQQSSPFFFQGTALGGL
                     PQEFTAYGGTQLSANYTAFLLGLGRNLGNWGAVSLDVTHARSQLADDSRHEGDSIRFL
                     YAKSMNTFGTNFQLMGYRYSTQGFYTLDDVAYRRMEGYEYDYDYDGEHRDEPIIVNYH
                     NLRFSRKDRLQLNISQSLNDFGSLYISGTHQKYWNTSDSDTWYQVGYTSSWVGISYSL
                     SFSWNESVGIPDNERIVGLNVSVPFNVLTKRRYTRENALDRAYASFNANRNSNGQNSW
                     LAGVGGTLLEGHNLSYHVSQGDTSNNGYTGSATANWQAAYGTLGVGYNYDRDQHDVNW
                     QLSGGVVGHENGITLSQPLGDTNVLIKAPGAGGVRIENQTGILTDWRGYAVMPYATVY
                     RYNRIALDTNTMGNSIDVEKNISSVVPTQGALVRANFDTRIGVRALITVTQGGKPVPF
                     GSLVRENSTGITSMVGDDGQVYLSGAPLSGELLVQWGDGANSRCIAHYVLPKQSLQQA
                     VTVISAVCTHPGS"
     misc_feature    652177..654756
                     /gene="fimD"
                     /locus_tag="ECs_0594"
                     /note="outer membrane usher protein FimD; Region:
                     PRK15198"
                     /db_xref="CDD:185120"
     gene            654772..655779
                     /gene="sfmH"
                     /locus_tag="ECs_0595"
                     /db_xref="GeneID:916951"
     CDS             654772..655779
                     /gene="sfmH"
                     /locus_tag="ECs_0595"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like adhesin protein"
                     /protein_id="NP_308622.2"
                     /db_xref="GeneID:916951"
                     /translation="MKIICRLLLAMACLCLANISWATVCANSTGVAEDEHYDLSNVFN
                     STNNQPGQIVVLPEKSGWVGVSAICPPGTLVNYTYRSYVTNFIVQETIDNYKYMQLND
                     YLLGAMSLVDSVMDIQFPPQNYIRMGTDPNVSQNLPFGVMDSRLIFRLKVIRPFINMV
                     EIPRQVMFTVYVTSTPYDPLVTPVYTISFGGRVEVPQNCELNAGQIVEFDFGDIGASL
                     FSAAGPGNRPAGVMPQTKSIAVKCTNVAAQAYLTMRLEASAVSGQAMVSDNQDLGFIV
                     ADQNDTPITPNDLNSVIPFRLDAAAAANVTLRAWPISITGQKPTEGPFSALGYLRVDY
                     Q"
     misc_feature    654772..655776
                     /gene="sfmH"
                     /locus_tag="ECs_0595"
                     /note="type 1 fimbrin D-mannose specific adhesin FimH;
                     Region: fimH; PRK15199"
                     /db_xref="CDD:237921"
     gene            655790..656305
                     /gene="sfmF"
                     /locus_tag="ECs_0596"
                     /db_xref="GeneID:916953"
     CDS             655790..656305
                     /gene="sfmF"
                     /locus_tag="ECs_0596"
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="NP_308623.1"
                     /db_xref="GeneID:916953"
                     /translation="MRRVFFSCFCGLLWSSSGWAADPLGTININLHGNVVDFSCTVNT
                     ADIDKTVDLGRWPTTQLLNAGDTTALLPFSLRLEGCPPGSVAILFTGTPASDANLLAL
                     DDPAMAQTVAIELRNSDRSRLALGEASPTEEVDANGNVTLNFFANYRALASGVRPGVA
                     KADAIFMINYN"
     misc_feature    655790..656302
                     /gene="sfmF"
                     /locus_tag="ECs_0596"
                     /note="fimbriae assembly protein; Region: PRK09934"
                     /db_xref="CDD:182153"
     gene            complement(656308..656940)
                     /gene="sfmZ"
                     /locus_tag="ECs_0597"
                     /db_xref="GeneID:916954"
     CDS             complement(656308..656940)
                     /gene="sfmZ"
                     /locus_tag="ECs_0597"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="NP_308624.1"
                     /db_xref="GeneID:916954"
                     /translation="MKPTSVIIMDTHPIIRMSIEVLLQKNSELQIVLKTDDYRITIDY
                     LRTRPVDLIIMDIDLPGTDGFTFLKRIKQIQSTVKVLFLSSKSECFYAGRAIQAGANG
                     FVSKCNDQNDIFHAVQMILSGYTFFPSETLNYIKSNKCSTNSSTVTVLSNREVTILRY
                     LVSGLSNKEIADKLLLSNKTVSAHKSNIYGKLGLHSIVELIDYAKLYELI"
     misc_feature    complement(656311..656940)
                     /gene="sfmZ"
                     /locus_tag="ECs_0597"
                     /note="fimbriae biosynthesis transcriptional regulator
                     FimZ; Region: PRK09935"
                     /db_xref="CDD:182154"
     gene            657183..657259
                     /gene="argU"
                     /locus_tag="ECs_R0030"
                     /db_xref="GeneID:62676041"
     tRNA            657183..657259
                     /gene="argU"
                     /locus_tag="ECs_R0030"
                     /product="tRNA-Arg"
                     /note="anticodon: tct"
                     /db_xref="GeneID:62676041"
     gene            complement(657305..658066)
                     /gene="envY"
                     /locus_tag="ECs_0598"
                     /db_xref="GeneID:916956"
     CDS             complement(657305..658066)
                     /gene="envY"
                     /locus_tag="ECs_0598"
                     /codon_start=1
                     /transl_table=11
                     /product="porin thermoregulatory transcriptional
                     activator"
                     /protein_id="NP_308625.1"
                     /db_xref="GeneID:916956"
                     /translation="MQLSSSEPCVVILTEKEVEVSVNNHATFTLPKNYLAAFACNNNV
                     IELSTLNHVLITHINRNIINDYLLFLNKNLTCVKPWSRLATPVIACHSRTPEVFRLAA
                     NHSKQQPSKPCEAELTRALLFTVLSNFLEQSRFIALLMYILRSSVRDSVCRIIQSDIQ
                     HYWNLRIVASSLCLSPSLLKKKLKNENTSYSQIVTECRMRYAVQMLLMDNKNITQVAQ
                     LCGYSSTSYFISVFKAFYGLTPLNYLAKQRQKVMW"
     misc_feature    complement(657320..658045)
                     /gene="envY"
                     /locus_tag="ECs_0598"
                     /note="DNA-binding transcriptional regulator GadX;
                     Provisional; Region: PRK09978"
                     /db_xref="CDD:137624"
     gene            complement(658249..659139)
                     /gene="ybcH"
                     /locus_tag="ECs_0599"
                     /db_xref="GeneID:916957"
     CDS             complement(658249..659139)
                     /gene="ybcH"
                     /locus_tag="ECs_0599"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308626.1"
                     /db_xref="GeneID:916957"
                     /translation="MRKFIFVLLTLLLVSPFSFAMKGIIWQPQNRDSQVTDTQWQGLM
                     SQLRLQGFDTLVLQWTRYGDAFTQPEQRALLFKRAAAAQQAGLKLIVGLNADPEFFMH
                     QKQSSAALESYLNRLLAADLQQARLWSAVPGVTPDGWYFSAEIDDLNWRSEAARQPLL
                     TWLNNAQRLISDVSAKPVYISSFFAGNMSPDGYRQLLEHVKATGVNVWVQDGSGVDKL
                     TAEQRERYLQASADCQSSAPASGIVYELFVAGKGKTFTAKPKPDAEIASLLAKRSSCG
                     KDTLYFSLRYLPVAHGILEY"
     misc_feature    complement(658252..659139)
                     /gene="ybcH"
                     /locus_tag="ECs_0599"
                     /note="DUF4434 family protein; Region: PRK09936"
                     /db_xref="CDD:182155"
     gene            complement(659140..662112)
                     /locus_tag="ECs_0600"
                     /db_xref="GeneID:916958"
     CDS             complement(659140..662112)
                     /locus_tag="ECs_0600"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage N4 receptor"
                     /protein_id="NP_308627.1"
                     /db_xref="GeneID:916958"
                     /translation="MKENNLNRVIGWSGLLLTSLLSTSALADNIGTSAEELGLSDYRH
                     FVIYPRLDKALKAQKNNDEATAIREFEYIHQQVPDNIPLTLYLAEAYRHFGHDDRARL
                     LLEDQLKRHPGDARLERSLAAIPVEVKSITTVEELLAQQKACDAAPTLRCRSEVGQNA
                     LRLAQLPVARAQLNDATFAASPEGKTLRTDLLQRAIYLKQWSQADTLYNEARQQNTLS
                     AAERRQWFDVLLAGQLDDRILALQSQGIFTDPQSYITYATALAYRGEKARLQHYLIEN
                     KPLFTTDAQEKSWLYLLSKYSANPVQALANYTVQFADNRQYVVGATLPVLLKEGQYDA
                     AQKLLATLPANEMLEERYAVSVATRNKAEALRLARLLYQQESANLTRLDQLTWQLMQN
                     EQSREAADLLLQRYPFQGDARISQTLMARLASLLESHPYLATPAKVAILSKPLPLAEQ
                     RQWQSQLPGIADNCPAIVRLLGDMSPSYDAAAWNRLAKCYRDTLPGVALYAWLQAEQR
                     QPNAWQHRAVAYQAYQVEDYATALAARQKISLHDMSNEDLLAAANTAQAAGNGAARDR
                     WLQQAEQRGLGSNALYWWLHAQRYIPGQPELALNDLTRSINIAPSANAYVARATIYRQ
                     RHNVPAAVSDLRAALELEPNNSNTQAALGYALWDSGDIAQSREMLEQAHKGLPDDPAL
                     IRQLAYVNQRLDDMPATQHYARLVIDDIDNQALITPLTPEQNQQRFNFRRLHEEVGRR
                     WTFSFDSSIGLRSGAMSTANNNVGGAAPGKSYRSYGQLEAEYRIGRNMLLEGDLLSVY
                     SRFFADTGENGVMMPVKNPMSGTGLRWKPLRDQIFFLAVEQQLPLNGQNGASDTMLRA
                     SASFFNGGKYSDEWHPNGSGWFAQNLYLDAAQYIRQDIQAWTADYRVSWHQKVANGQT
                     IEPYAHVQDNGYRDKGTQGAQLGGVGVRWNIWTGETHYDAWPHKVSLGVEYQHTFKAI
                     NQRNGERNNAFLTIGVHW"
     misc_feature    complement(659143..662103)
                     /locus_tag="ECs_0600"
                     /note="bacteriophage N4 receptor, outer membrane subunit;
                     Provisional; Region: PRK09782"
                     /db_xref="CDD:236624"
     misc_feature    complement(660190..660282)
                     /locus_tag="ECs_0600"
                     /note="TPR repeat [structural motif]; Region: TPR repeat"
                     /db_xref="CDD:276809"
     misc_feature    complement(660091..660177)
                     /locus_tag="ECs_0600"
                     /note="TPR repeat [structural motif]; Region: TPR repeat"
                     /db_xref="CDD:276809"
     gene            complement(662099..664336)
                     /gene="nfrB"
                     /locus_tag="ECs_0601"
                     /db_xref="GeneID:916959"
     CDS             complement(662099..664336)
                     /gene="nfrB"
                     /locus_tag="ECs_0601"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="NP_308628.1"
                     /db_xref="GeneID:916959"
                     /translation="MDWLLDVFATWLYGLKVIAITLAVIMFISGLDDFFIDVVYWVRR
                     IKRKLSVYRRYPRMSYRELYKPDEKPLAIMVPAWNETGVIGNMAELAATTLDYENYHI
                     FVGTYPNDPDTQRDVDEVCARFPNVHKVVCARPGPTSKADCLNNVLDAITQFERSANF
                     AFAGFILHDAEDVISPMELRLFNYLVERKDLIQIPVYPFEREWTHFTSMTYIDEFSEL
                     HGKDVPVREALAGQVPSAGVGTCFSRRAVTALLADGDGIAFDVQSLTEDYDIGFRLKE
                     KGMTEIFVRFPVVDEAKEREQRKFLQHARTSNMICVREYFPDTFSTAVRQKSRWIIGI
                     VFQGFKTHKWTSSLTLNYFLWRDRKGAISNFVSFLAMLVMIQLLLLLAYESLWPDAWH
                     FLSIFSGSAWLMTLLWLNFGLMVNRIVQRVIFVTGYYGLTQGLLSVLRLFWGNLINFM
                     ANWRALKQVLQHGDPRRVAWDKTTHDFPSVTGDTRSLRPLGQILLENQVITEEQLDTA
                     LRNRVEGLRLGGSMLMQGLISAEQLAQALAEQNGVAWESIDAWQIPSSLIAEMPASVA
                     LHYAVLPLRLENDELIVGSEDGIDPVSLAALTRKVGRKVRYVIVLRGQIVTGLRHWYA
                     RRRGHDPRAMLYNAVQHQWLTEQQAGEIWRQYVPHQFLFAEILTTLGHINRSAINVLL
                     LRHERSSLPLGKFLVTEGVISQETLDRVLTIQRELQVSMQSLLLKAGLNTEQVAQLES
                     ENEGE"
     misc_feature    complement(662126..664318)
                     /gene="nfrB"
                     /locus_tag="ECs_0601"
                     /note="phage adsorption protein NrfB; Region: nfrB;
                     PRK11234"
                     /db_xref="CDD:236884"
     repeat_region   complement(664592..665857)
                     /note="ISEc1 Family: ISAs1 partial"
     gene            complement(664602..665738)
                     /gene="ydcC"
                     /locus_tag="ECs_0602"
                     /db_xref="GeneID:916960"
     CDS             complement(664602..665738)
                     /gene="ydcC"
                     /locus_tag="ECs_0602"
                     /codon_start=1
                     /transl_table=11
                     /product="H repeat-associated protein"
                     /protein_id="NP_308629.1"
                     /db_xref="GeneID:916960"
                     /translation="MELKKLMEHISIIPDYRQAWKVEHKLSDILLLTICAVISGAEGW
                     EDIEDLGETHLNFLKQYGDFENGIPVHDTIARVVSCISPAKFHECFINWMRDCHSSDD
                     KDVIAIDGKTLRHSYDKSRRRRAIHVISAFSTMHSLVIGQIKTDEKSNEITAIPELLN
                     MLDIKGKIITTDAMGCQKDIAEKIQKQGGDYLFAVKGNQGRLNKAFEEKFPLKELNNP
                     EHDSYAMSEKSHGREEIRLHIVCDVPDELIDFTFEWKGLKKLCVAVSFRSIIAEQKKE
                     SEMTVRYYISSADLTAEKFATAIRNHWHVENKLHWRLDVVVNEDDCKIRRGNAAELFS
                     GIRHIAINILTNDKVFKAGLRRKMRKAAMDRNYLASVFAGSGLS"
     misc_feature    complement(664707..665654)
                     /gene="ydcC"
                     /locus_tag="ECs_0602"
                     /note="ISAs1 family transposase; Region: transpos_ISAs1;
                     NF033564"
                     /db_xref="CDD:411194"
     misc_feature    complement(<664605..664790)
                     /gene="ydcC"
                     /locus_tag="ECs_0602"
                     /note="Predicted transposase YbfD/YdcC associated with H
                     repeats [Mobilome: prophages, transposons]; Region: YhhI;
                     COG5433"
                     /db_xref="CDD:227720"
     gene            complement(666201..667535)
                     /locus_tag="ECs_0603"
                     /db_xref="GeneID:916961"
     CDS             complement(666201..667535)
                     /locus_tag="ECs_0603"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion protein Rhs"
                     /protein_id="NP_308630.1"
                     /db_xref="GeneID:916961"
                     /translation="MTASGTGLGYGEGDESYGYDSCGYLKAQSAGGHRISEETDQYAG
                     GHRLKQAGNTQYDYDAAGRMVSRTRHRDGYRPETERFRWDSRDQLTGYCSAQGEQWEY
                     RHDASGRRTEKRCDRKKIRFTYLWDGDSIAEIREYRDDELYSVRHLVFNGFELISQQC
                     SRVRQPHPSVAPQWVTRTNHAVNDLTGRPLMLFNSEGKTVWRPGQTSLWGLALSLPAD
                     TDYPDPRGERDAEADPGLLYAGQWQDAESGLCYNRFRYYEPETGMYLVSDPLGLQGGE
                     QTYRYVPNPCGWVDPLGLAASSKISSLMDYIGDGRRVSGHTGFLDGVRLSRSQINNIA
                     KEMEKLGIKVIRKADKYLPPNARAAFDYGLRNIYLRKNATLYEVYHEVIHAKQFAKIG
                     REAYEALGRLSREEHVLNEILKSKNLFNEAEIAHAIKYVEGLREKFMMGLIN"
     misc_feature    complement(666204..>667508)
                     /locus_tag="ECs_0603"
                     /note="Uncharacterized conserved protein RhsA, contains 28
                     RHS repeats [General function prediction only]; Region:
                     RhsA; COG3209"
                     /db_xref="CDD:225750"
     gene            complement(667704..668111)
                     /locus_tag="ECs_0604"
                     /db_xref="GeneID:916962"
     CDS             complement(667704..668111)
                     /locus_tag="ECs_0604"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308631.1"
                     /db_xref="GeneID:916962"
                     /translation="MKEIDLLYENIYQLLIKPYLLDLSSQSGKKIELNYTCKIKDAAD
                     EIKGSMIFNDVDGKQKATCTIRVLILKTFHDGRYRFVIESVIYDLINNYSGFILTGRL
                     FWQGEGFGHELFPVTNKYNAWRWKNKKIIDISW"
     gene            complement(668129..672979)
                     /locus_tag="ECs_0605"
                     /db_xref="GeneID:916963"
     CDS             complement(668129..672979)
                     /locus_tag="ECs_0605"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion protein Rhs"
                     /protein_id="NP_308632.1"
                     /db_xref="GeneID:916963"
                     /translation="MSEGPGGPQGATAGGTLAMRMLSQRAMAASQMKRAANDKAIAQM
                     LASKKSGPPAARLGDEIQHKSFLGALAGAVLGAIVTIAEGCLIMAACATGPYALVLVP
                     ALMYASYKASDYVEEKQNQLESWINSFCDTDGAINTGSKNVKINGKPAARAAVTLPPP
                     PPPGAIPEVPQGEPSWGDIATDLLESAAEKAVPLAKAWGNAVITLTDSNAGFMDRVSA
                     GASLLFPAGPVLMEFATMVGGRGEIKKDVDFPEAGEDTALCDKENKPPRIAQGSSNVF
                     INNQPAARKGDKLECSAAIVEGSPDVFIGGEQVTYLDIQPEFPPWQRMILGGITIASY
                     LLPPAGLLGKLGNLAKLGKLGNLLGKSGKLLGAKLGALLGKTGNSLKSIANKVIRWVT
                     DPVDPVTGAYCDERTDFTLGQTLPLSFTRFHSSVLPLHGLTGVGWSDSWSEYAWVREQ
                     GNRVDVISLGATLNFAFDGESDTAVNPYHAQYILRRRDDYLELFDRDALSSRFFYDAF
                     PGMRLRHPVTDDTSDDRLAHSPADRMYMLGGMSDTASNRITFERDTQYRITGVSHTDG
                     IRLKLTYHASGYLKAIHRTDNGIQTLATYEQDARLDYHLFYEYDAADRIIRWSDNDQT
                     WSRFTYDAQGRCVTVTGAEGYYNATLDYGDGCTTVTDGKGIHRYYYDPDGNILREEAP
                     DGSTTTYEWDEFHHLLARHSPAGRVEKFEYNAAHGQLSRYTAADGADWQYCYDERGLL
                     SNITAPAGQTWTQQCDERGLPVSLVSPQGEETRLAYTPQGLLSGIFRQDERRLGIEYD
                     HHNWPETLTDVMGREHHTEYSGHDLPVKMRGPGGQSVRLQWQQHHKLSGLERAGTGAE
                     GFRYDRHGNLLAYTDGNGVVWTMEYGPFDLPVARTDGEGHRWQYRYDKDTLQLTEVIN
                     PQGESYLYILDNCGRVTEERDWGGVVCRYRYDADGLCTARVNGLEETILYSRDAAGRL
                     AEVITPEGKTQYAYDKSGRLTGIFSPDGTSQRTGYDERGRVNVTTQGRRAIEYHYPDE
                     HTVIRCILPPEDERDRHPDGSLLKTTYRYNAAGELTEVILPGDETLTFSRDEAGREVL
                     RHSNRGFACEQGWNAAGQPVSQRAGLFPAEATWGGLLPSLLREYRYDSAGNVSGVTSR
                     EDYGRETHREYRLDRNGQVTAVTASGTGLGYGEGDETYGYDSCGYLKAQSAGRHRISG
                     ETDQYAAGHRLKQAGNTQYDYDAAGRMVSRTKHRDGYRPETERFRWDSRDQLTGYRSA
                     QGEQWEYRHDASGRRTEKRCDRKKIRFTYLWDGDSIAEIREYRDDKLYSVRHLVFNGF
                     ELISQQFSRVRQPHPSVAPQWVTRTNHAVSDLTGRPLMLFNSEGKTVWRPGQTSLWGL
                     ALSLPADTDYPDPRGERDPEADPGLLYAGQWQDAESGLCYNRFRYYEPETGMYLVSDP
                     LGLQGGEQTYRYVPNPCGYIDPLGLAICQLARWTKWGSEQSNISDVLNSLGNRALKYA
                     NGDWIKSEAAFNKYINMINKRLELTGSKFRVEIQPAIKNGERVPATTNGPFKVNGKWT
                     SGTHYTGGSKRLDAGIIDITSPTNQYGLHPVIEGFDITLNKTKPSAVDIYSDVFGGID
                     INDFRL"
     misc_feature    complement(672065..>672226)
                     /locus_tag="ECs_0605"
                     /note="proline-alanine-alanine-arginine (PAAR) domain,
                     also containing C-terminal Rearrangement hotspot (Rhs)
                     extensions; Region: PAAR_RHS; cd14742"
                     /db_xref="CDD:269827"
     misc_feature    complement(671615..671803)
                     /locus_tag="ECs_0605"
                     /note="Domain of unknown function (DUF6531); Region:
                     DUF6531; pfam20148"
                     /db_xref="CDD:437980"
     misc_feature    complement(671201..671323)
                     /locus_tag="ECs_0605"
                     /note="YD repeat (two copies); Region: YD_repeat_2x;
                     TIGR01643"
                     /db_xref="CDD:273728"
     misc_feature    complement(671048..671155)
                     /locus_tag="ECs_0605"
                     /note="RHS Repeat; Region: RHS_repeat; pfam05593"
                     /db_xref="CDD:428530"
     misc_feature    complement(670847..670972)
                     /locus_tag="ECs_0605"
                     /note="YD repeat (two copies); Region: YD_repeat_2x;
                     TIGR01643"
                     /db_xref="CDD:273728"
     misc_feature    complement(668132..670834)
                     /locus_tag="ECs_0605"
                     /note="Uncharacterized conserved protein RhsA, contains 28
                     RHS repeats [General function prediction only]; Region:
                     RhsA; COG3209"
                     /db_xref="CDD:225750"
     gene            complement(672999..673460)
                     /locus_tag="ECs_0606"
                     /db_xref="GeneID:916964"
     CDS             complement(672999..673460)
                     /locus_tag="ECs_0606"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308633.1"
                     /db_xref="GeneID:916964"
                     /translation="MQFTFNEGHIQLPSQWQDQSMQVLVSTDNSGINLVITREPVSQG
                     TLTPELYQETLALYQGKLDGYTEHACREITLAEAPAWLLDYSWNGPEDEGNQGRISQI
                     AVFQRRGDTLLTFTFSTSLSLKNSQKTMLLEVIKSFTPLPPENDIQKDQPR"
     misc_feature    complement(673023..673460)
                     /locus_tag="ECs_0606"
                     /note="Uncharacterized protein [Function unknown]; Region:
                     COG5435"
                     /db_xref="CDD:227722"
     gene            complement(673488..675389)
                     /locus_tag="ECs_0607"
                     /db_xref="GeneID:916965"
     CDS             complement(673488..675389)
                     /locus_tag="ECs_0607"
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system Vgr family protein"
                     /protein_id="NP_308634.1"
                     /db_xref="GeneID:916965"
                     /translation="MSTGLRFTLEVDGLPPDAFAVVSFHLTQSLSSLFSLDLSLVSQQ
                     FLSLEFAQVLDKMAYLTIWQGDDVQRRVKGVVTWFELGENDKNQMLYSMKVHPPLWRA
                     GLRQNFRIFQNEDIKSILGTILQENGVTEWSPLFSEPHPSREFCVQYGETDYDFLCRM
                     AAEEGIFFYEEHAYKSTDQSLVLCDTVRHLPESFEIPWNPNTRTEVSTLCISQFRYSA
                     QIRPSSVVTKDYTFKRPGWAGRFDQEGQHQDYQRTQYEVYDYPGRFKGAHGQNFARWQ
                     MEGWRNNAETARGMSRSPEIWPGRRIVLTGHPQANLNREWQVVASELHGEQPQAVPGR
                     RGAGTALENHFAVIPADRTWRPQPRLKPLVDGPQSAVVTGPEGEEIFCDEHGRVRVKF
                     NWDRYNPADQDSSCWIRVAQAWAGTGFGNLAIPRVGQEVIVDFLNGDPDQPIIMGRTY
                     HQENRTPGSLPGTKTQMTIRSKTYMGSGFNELKFDDATGREQVYIHAQKNMDTEVLND
                     RTTTVKHDHRETVKNDQTVTIQEGNRLLTVEKGHKITGVLKGSLSEDVFQDRGTIAGS
                     VHVDAVNNGGEGNGIQAYTAIKEIMLAVEESKIALTPDGIQLQVGESTVIRLSKDGIT
                     IVGGSVFIN"
     misc_feature    complement(673839..675371)
                     /locus_tag="ECs_0607"
                     /note="type VI secretion system Vgr family protein;
                     Region: VI_Rhs_Vgr; TIGR03361"
                     /db_xref="CDD:274542"
     gene            complement(675983..677431)
                     /gene="cusS"
                     /locus_tag="ECs_0608"
                     /db_xref="GeneID:916966"
     CDS             complement(675983..677431)
                     /gene="cusS"
                     /locus_tag="ECs_0608"
                     /codon_start=1
                     /transl_table=11
                     /product="copper-sensing histidine kinase in two-component
                     regulatory system with CusR"
                     /protein_id="NP_308635.1"
                     /db_xref="GeneID:916966"
                     /translation="MVSKPFQRPFSLATRLTFFISLATIAAFFAFAWIMIHSVKVHFA
                     EQDINDLKEISATLERVLNHPDETQARRLMTLEDIVSGYSNVLISLADSHGKTVYHSP
                     GAPDIREFARDAIPDKDARGGEVFLLSGPTMMMPGHGHGHMEHSNWRMISLPVGPLVD
                     GKPIYTLYIALSIDFHLHYINDLMNKLIMTASVISILIVFIVLLAVHKGHAPIRSVSR
                     QIQNITSKDLDVRLDPQTVPIELEQLVLSFNHMIERIEDVFTRQSNFSADIAHEIRTP
                     ITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLIPEKK
                     MLNLADEVGKVFDFFEALAEDRGVELQFVGDECQVAGDPLMLRRALSNLLSNALRYTP
                     PGEAIVVRCQTVDHLVQVIVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLA
                     IVKSIVVAHKGTVAVTSNARGTRFVIVLPERG"
     misc_feature    complement(675986..677431)
                     /gene="cusS"
                     /locus_tag="ECs_0608"
                     /note="Cu(+)/Ag(+) sensor histidine kinase; Region:
                     PRK09835"
                     /db_xref="CDD:182101"
     gene            complement(677421..678104)
                     /gene="cusR"
                     /locus_tag="ECs_0609"
                     /db_xref="GeneID:916967"
     CDS             complement(677421..678104)
                     /gene="cusR"
                     /locus_tag="ECs_0609"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component regulatory system response
                     regulator CusR"
                     /protein_id="NP_308636.1"
                     /db_xref="GeneID:916967"
                     /translation="MKLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGD
                     YDLIILDIMLPDVNGWDIVRMLRSANKGMPILLLTALGTIEHRVKGLELGADDYLVKP
                     FAFAELLARVRTLLRRGAAVIIESQFQVADLMVDLVSRKVTRSGTRITLTSKEFTLLE
                     FFLRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRGKIDNDFEPKLIQTVRGVG
                     YMLEVPDGQ"
     misc_feature    complement(677424..678104)
                     /gene="cusR"
                     /locus_tag="ECs_0609"
                     /note="DNA-binding transcriptional activator CusR;
                     Provisional; Region: PRK09836"
                     /db_xref="CDD:182102"
     gene            678261..679643
                     /gene="cusC"
                     /locus_tag="ECs_0610"
                     /db_xref="GeneID:916968"
     CDS             678261..679643
                     /gene="cusC"
                     /locus_tag="ECs_0610"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane component of copper/silver efflux
                     system"
                     /protein_id="NP_308637.1"
                     /db_xref="GeneID:916968"
                     /translation="MSPCKLLPFCVALALTGCSLAPDYQRPAMPVPQQFSLSQNGLVN
                     AADNYQNAGWRTFFVDNQVKTLISEALENNRDLRMATLKVQEARAQYRLTDADRYPQL
                     NGEGSGSWSGNLKGDSATTREFSTGLNASFDLDFFGRLKNMSEAERQNYLATEEAQRA
                     VHILLVSNVAQSYFNQQLAYAQLQIAEETLRNYQQSYAFVEKQLLTGSSNVLALEQAR
                     GVIESTRSDIAKRQGELAQANNALQLLLGSYGKLPQAQTVNSDSLQSVKLPAGLSSQI
                     LLQRPDIMEAEHALMAANANIGAARAAFFPSISLTSGISTASSDLSSLFNASSGMWNF
                     IPKIEIPIFNAGRNQANLDIAEIRQQQSVVNYEQKIQNAFKEVADALALRQSLNDQIS
                     AQQRYLASLQITLQRARALYQHGAVSYLEVLDAERSLFATRQTVLDLNYARQVNEISL
                     YTALGGGWQQ"
     misc_feature    678261..679640
                     /gene="cusC"
                     /locus_tag="ECs_0610"
                     /note="Cu(I)/Ag(I) efflux RND transporter outer membrane
                     protein; Region: PRK09837"
                     /db_xref="CDD:182103"
     gene            679667..679999
                     /gene="cusF"
                     /locus_tag="ECs_0611"
                     /db_xref="GeneID:916969"
     CDS             679667..679999
                     /gene="cusF"
                     /locus_tag="ECs_0611"
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(I)/Ag(I) efflux system periplasmic protein
                     CusF"
                     /protein_id="NP_308638.1"
                     /db_xref="GeneID:916969"
                     /translation="MKKALQVAMFSLFTVIGFNAQANEHHHETMSEAQPQVISATGVV
                     KGFDLESKKITIHHDPIAAVNWPEMTMRFTITPQTKMSGIKTGDKVAFNFVQQGNLSL
                     LQDIKVSQ"
     misc_feature    679667..679996
                     /gene="cusF"
                     /locus_tag="ECs_0611"
                     /note="periplasmic copper-binding protein; Provisional;
                     Region: PRK09838"
                     /db_xref="CDD:182104"
     gene            680015..681238
                     /gene="cusB"
                     /locus_tag="ECs_0612"
                     /db_xref="GeneID:916970"
     CDS             680015..681238
                     /gene="cusB"
                     /locus_tag="ECs_0612"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane fusion protein of copper/silver efflux
                     system"
                     /protein_id="NP_308639.1"
                     /db_xref="GeneID:916970"
                     /translation="MKKIALIIGSMIAGGIISAAGFTWFAKAEPPAEKTSTAERKILF
                     WYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSASGVRIDPTQTQNLGVKTATVTRG
                     PLTFAQSFPANVSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGAPLLDLTIPDWVE
                     AQSEYLLLRETGGTATQTEGILERLRLAGMPEADIRRLIATQKIQTRFTLKAPIDGVI
                     TAFDLRAGMNIAKDNVVAKIQGMDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTL
                     TIRKWTLLPGVDAATRTLQLRLEVDNADEALKPGMNAWLQLNTASEPMLLIPSQALID
                     TGSEQRVITVDADGRFVPKRVAVFQASQGVTALRSGLAEGEKVVSSGLFLIDSEANIS
                     GALERMRSESATHAH"
     misc_feature    680015..681235
                     /gene="cusB"
                     /locus_tag="ECs_0612"
                     /note="copper/silver efflux system membrane fusion protein
                     CusB; Provisional; Region: PRK09783"
                     /db_xref="CDD:236625"
     gene            681250..684387
                     /gene="cusA"
                     /locus_tag="ECs_0613"
                     /db_xref="GeneID:916972"
     CDS             681250..684387
                     /gene="cusA"
                     /locus_tag="ECs_0613"
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver efflux system"
                     /protein_id="NP_308640.1"
                     /db_xref="GeneID:916972"
                     /translation="MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSD
                     VQVIIKTSYPGQAPQIVENQVTYPLTTTMLSVPGAKTVRGFSQFGDSYVYVIFEDGTD
                     PYWARSRVLEYLNQVQGKLPAGVSAELGPDATGVGWIYEYALVDRSGKHDLADLRSLQ
                     DWFLKYELKTIPDVAEVASVGGVVKEYQVVIDPQRLAQYGISLAEVKSALDASNQEAG
                     GSSIELAEAEYMVRASGYLQTLDDFNHIVLKASENGVPVYLRDVAKIQVGPEMRRGIA
                     ELNGEVVGGVVILRSGKNAREVIAAVKDKLETLKSSLPEGVEIVTTYDRSQLIDRAID
                     NLSGKLLEEFIVVAVVCALFLWHVRSALVAIISLPLGLCIAFIVMHFQGLNANIMSLG
                     GIAIAVGAMVDAAIVMIENAHKRLEEWQHQHPDATLDNKTRWQVITNASVEVGPALFI
                     SLLIITLSFIPIFTLEGQEGRLFGPLAFTKTYAMAGAALLAIVVIPILMGYWIRGKIP
                     PESSNPLNRFLIRVYHPLLLKVLHWPKTTLLVAALSVLTVLWPLNKVGGEFLPQINEG
                     DLLYMPSTLPGISAAEAASMLQKTDKLIMSVPEVARVFGKTGKAETATDSAPLEMVET
                     TIQLKPQEQWRPGMTMDKIIEELDNTVRLPGLANLWVPPIRNRIDMLSTGIKSPIGIK
                     VSGTVLADIDAMAEQIEEVARTVPGVASALAERLEGGRYINVEINREKAARYGMTVAD
                     VQLFVTSAVGGAMVGETVEGIARYPINLRYPQSWRDSPQALRQLPILTPMKQQITLAD
                     VADVKVSTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQKAIAEKVQLKPGTSVAF
                     SGQFELLERANHKLKLMVPMTLMIIFVLLYLAFRRVGEALLIISSVPFALVGGIWLLW
                     WMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRHAIEAEPSLNNPQTFSEQKLDEALH
                     HGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAPLLSLFIIP
                     AAYKLMWLHRHRVRK"
     misc_feature    681250..684384
                     /gene="cusA"
                     /locus_tag="ECs_0613"
                     /note="heavy metal efflux pump, CzcA family; Region:
                     2A0601; TIGR00914"
                     /db_xref="CDD:129992"
     gene            684489..685865
                     /gene="pheP"
                     /locus_tag="ECs_0614"
                     /db_xref="GeneID:916973"
     CDS             684489..685865
                     /gene="pheP"
                     /locus_tag="ECs_0614"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine transporter"
                     /protein_id="NP_308641.1"
                     /db_xref="GeneID:916973"
                     /translation="MKNASNVSEDTASNQEPTLHRGLHNRHIQLIALGGAIGTGLFLG
                     IGPAIQMAGPAVLLGYGVAGIIAFLIMRQLGEMVVEEPVSGSFAHFAYKYWGPFAGFL
                     SGWNYWVMFVLVGMAELTAAGIYMQYWFPDVPTWIWAAAFFIIINAVNLVNVRLYGET
                     EFWFALIKVLAIIGMIGFGLWLLFSGHGGEKASIDNLWRYGGFFATGWNGLILSLAVI
                     MFSFGGLELIGITAAEARDPEKSIPKAVNQVVYRILLFYIGSLVVLLALYPWVEVKSN
                     SSPFVMIFHNLDSNVVASALNFVILVASLSVYNSGVYSNSRMLFGLSVQGNAPKFLTR
                     VSRRGVPINSLMLSGAITSLVVLINYLLPQKAFGLLMALVVATLLLNWIMICLAHLRF
                     RAAMRRQGRETQFKALLYPFGNYLCIAFLAMILLLMCTMDDMRLSAILLPVWIVFLFV
                     AFKTLRRK"
     misc_feature    684489..685862
                     /gene="pheP"
                     /locus_tag="ECs_0614"
                     /note="phenylalanine transporter; Provisional; Region:
                     PRK10249"
                     /db_xref="CDD:236667"
     gene            complement(685933..687180)
                     /gene="ybdG"
                     /locus_tag="ECs_0615"
                     /db_xref="GeneID:916974"
     CDS             complement(685933..687180)
                     /gene="ybdG"
                     /locus_tag="ECs_0615"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel protein"
                     /protein_id="NP_308642.1"
                     /db_xref="GeneID:916974"
                     /translation="MQDLISHVEDLAGIEIDHTTSMVMIFGIIFLTAVVVHIILHWVV
                     LRTFEKRAIASSRLWLQIITQNKLFHRLAFTLQGIIVNIQAVFWLQKGTEAADILTTC
                     AQLWIMMYALLSVFSLLDVILNLAQKFPAASQLPLKGIFQGIKLIGAILVGILMISLL
                     IGQSPAILISGLGAMAAVLMLVFKDPILGLVAGIQLSANDMLKLGDWLEMPKYGADGA
                     VIDIGLTTVKVRNWDNTITTIPTWSLVSDSFKNWSGMSASGGRRIKRSISIDVTSIRF
                     LDEDEMQRLNKAHLLKPYLTSRHQEINEWNRQQGSTESVLNLRRMTNIGTFRAYLNEY
                     LRNHPRIRKDMTLMVRQLAPGDNGLPLEIYAFTNTVVWLEYESIQADIFDHIFAIVEE
                     FGLRLHQSPTGNDIRSLAGAFKQ"
     misc_feature    complement(686422..>687102)
                     /gene="ybdG"
                     /locus_tag="ECs_0615"
                     /note="Small-conductance mechanosensitive channel [Cell
                     wall/membrane/envelope biogenesis]; Region: MscK; COG3264"
                     /db_xref="CDD:225803"
     misc_feature    complement(685993..686751)
                     /gene="ybdG"
                     /locus_tag="ECs_0615"
                     /note="Mechanosensitive ion channel; Region: MS_channel;
                     pfam00924"
                     /db_xref="CDD:425948"
     gene            complement(687288..687941)
                     /gene="nfsB"
                     /locus_tag="ECs_0616"
                     /db_xref="GeneID:916975"
     CDS             complement(687288..687941)
                     /gene="nfsB"
                     /locus_tag="ECs_0616"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteridine reductase"
                     /protein_id="NP_308643.1"
                     /db_xref="GeneID:916975"
                     /translation="MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQ
                     PWHFIVASTEEGKARVAKSAAGNYVFNERKILDASHVVVFCAKTAMDDAWLKLVVDQE
                     DADGRFATPEAKAANDKGRKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLD
                     AVPIEGFDAAILDAEFGLKEKGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV"
     misc_feature    complement(687291..687941)
                     /gene="nfsB"
                     /locus_tag="ECs_0616"
                     /note="oxygen-insensitive NAD(P)H nitroreductase; Region:
                     PRK11053"
                     /db_xref="CDD:182929"
     misc_feature    complement(order(687312..687332,687414..687416,
                     687444..687449,687471..687476,687483..687488,
                     687495..687500,687507..687512,687516..687521,
                     687528..687533,687786..687806,687810..687812,
                     687816..687818,687822..687824,687828..687842,
                     687846..687851,687855..687857,687912..687914,
                     687918..687920,687930..687935))
                     /gene="nfsB"
                     /locus_tag="ECs_0616"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:380324"
     misc_feature    complement(order(687321..687323,687327..687329,
                     687444..687458,687507..687512,687516..687518,
                     687720..687722,687729..687731,687816..687830,
                     687900..687902,687906..687914))
                     /gene="nfsB"
                     /locus_tag="ECs_0616"
                     /note="FMN binding site [chemical binding]; other site"
                     /db_xref="CDD:380324"
     gene            complement(688035..688403)
                     /gene="ybdF"
                     /locus_tag="ECs_0617"
                     /db_xref="GeneID:916976"
     CDS             complement(688035..688403)
                     /gene="ybdF"
                     /locus_tag="ECs_0617"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_308644.1"
                     /db_xref="GeneID:916976"
                     /translation="MDKQSLHETAKRLALELPFVELCWPFGPEFDVFKIGGKIFMLSS
                     ELRGVPFINLKSDPQKSLLNQQIYPSIKPGYHMNKKHWISVYPGEEISEALLRDLIND
                     SWNLVVDGLAKRDQKRVRPG"
     misc_feature    complement(688038..688403)
                     /gene="ybdF"
                     /locus_tag="ECs_0617"
                     /note="MmcQ/YjbR family DNA-binding protein; Region:
                     PRK10250"
                     /db_xref="CDD:182333"
     gene            complement(688468..688716)
                     /gene="ybdJ"
                     /locus_tag="ECs_0618"
                     /db_xref="GeneID:916977"
     CDS             complement(688468..688716)
                     /gene="ybdJ"
                     /locus_tag="ECs_0618"
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein"
                     /protein_id="NP_308645.1"
                     /db_xref="GeneID:916977"
                     /translation="MKHPLETLTTAAGILLMAFLSCLLLPAPALGLTLAQKLVTTFHL
                     MDLSQLYTLLFCLWFLVLGAIEYFVLRFIWRRWFSLAD"
     misc_feature    complement(688480..688713)
                     /gene="ybdJ"
                     /locus_tag="ECs_0618"
                     /note="Protein of unknown function (DUF1158); Region:
                     DUF1158; pfam06643"
                     /db_xref="CDD:399557"
     gene            complement(688782..689900)
                     /gene="ybdK"
                     /locus_tag="ECs_0619"
                     /db_xref="GeneID:916978"
     CDS             complement(688782..689900)
                     /gene="ybdK"
                     /locus_tag="ECs_0619"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl:cysteine ligase"
                     /protein_id="NP_308646.1"
                     /db_xref="GeneID:916978"
                     /translation="MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDAVKNK
                     ITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAAADHHLEICGGGTHPF
                     QKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPH
                     FIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMID
                     SIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHKEKD
                     YLLYKFNRFQACRYGLEGVITDPYTGDRRPLTEDTLRLLEKIAPSAHKIGASSAIEAL
                     HRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGD"
     misc_feature    complement(688785..689900)
                     /gene="ybdK"
                     /locus_tag="ECs_0619"
                     /note="gamma-glutamyl:cysteine ligase; Provisional;
                     Region: PRK13516"
                     /db_xref="CDD:237407"
     gene            690339..690491
                     /gene="hokE"
                     /locus_tag="ECs_0620"
                     /db_xref="GeneID:916979"
     CDS             690339..690491
                     /gene="hokE"
                     /locus_tag="ECs_0620"
                     /codon_start=1
                     /transl_table=11
                     /product="small toxic membrane polypeptide HokE"
                     /protein_id="NP_308647.1"
                     /db_xref="GeneID:916979"
                     /translation="MLTKYALVAVIVLCLTVPGFTLLVGDSLCEFTVKERNIEFRAVL
                     AYEPKK"
     misc_feature    690339..690488
                     /gene="hokE"
                     /locus_tag="ECs_0620"
                     /note="Hok/gef family; Region: HOK_GEF; cl27487"
                     /db_xref="CDD:452751"
     gene            690842..690994
                     /gene="mokC"
                     /locus_tag="ECs_0621"
                     /db_xref="GeneID:916980"
     CDS             690842..690994
                     /gene="mokC"
                     /locus_tag="ECs_0621"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory peptide MokC whose translation
                     enables hok (gef) expression"
                     /protein_id="NP_308648.2"
                     /db_xref="GeneID:916980"
                     /translation="MLTKYALVAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVL
                     AYEPKK"
     misc_feature    690842..690991
                     /gene="mokC"
                     /locus_tag="ECs_0621"
                     /note="Hok/gef family; Region: HOK_GEF; cl27487"
                     /db_xref="CDD:452751"
     gene            complement(691116..691859)
                     /gene="entD"
                     /locus_tag="ECs_0622"
                     /db_xref="GeneID:916981"
     CDS             complement(691116..691859)
                     /gene="entD"
                     /locus_tag="ECs_0622"
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase entD"
                     /protein_id="NP_308649.3"
                     /db_xref="GeneID:916981"
                     /translation="MNALSGLQKSCQFNILQDHVGLISVAHQAVLRLSSVSNMVDMKT
                     THTSLPFAGHTLHFVEFDPANFCEQDLLWLPHYAQLQHAGRKRKTEHLAGRIAAVYAL
                     REYGYKCVPAIGELRQPVWPAEVYGSISHCGATALAVVSRQPIGVDIEEIFSAQTATE
                     LTDNIITPAEHERLADCGLAFSLALTLAFSAKESAFKASEIQTDAGFLDYQIISWNKQ
                     QVIIHRENEMFAVHWQIKEKIVITLCQHD"
     misc_feature    complement(691125..691745)
                     /gene="entD"
                     /locus_tag="ECs_0622"
                     /note="enterobactin synthase subunit EntD; Region:
                     PRK10251"
                     /db_xref="CDD:182334"
     gene            complement(691911..694151)
                     /gene="fepA"
                     /locus_tag="ECs_0623"
                     /db_xref="GeneID:916982"
     CDS             complement(691911..694151)
                     /gene="fepA"
                     /locus_tag="ECs_0623"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrienterobactin outer membrane transporter"
                     /protein_id="NP_308650.1"
                     /db_xref="GeneID:916982"
                     /translation="MNKKIHSLALLVNLGIYGVAQAQEPTDTPVSHDDTIVVTAAEQN
                     LQAPGVSTITADEIRKNPVARDVSEIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPE
                     NTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAA
                     GGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLD
                     KTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYS
                     RQGNLYAGDTQNTNSDAYTRSKYGDETNRLYRQNYSLTWNGGWDNGVTTSNWVQYEHT
                     RNSRIPEGLAGGTEGKFNEKATQDFVDNDLDDVMLHSEVNLPIDFLVNQTLTLGTEWN
                     QQRMKDLSSNTQALTGTNTGGAIDGVSATDRSPYSKAEIFSLFAENNMELTDSTIVTP
                     GLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQG
                     CYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGITWFRNDYRNKIEAGYVAVG
                     QNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSII
                     PEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLS
                     ATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYM
                     SVNTHF"
     misc_feature    complement(691914..694151)
                     /gene="fepA"
                     /locus_tag="ECs_0623"
                     /note="FepA family TonB-dependent siderophore receptor;
                     Region: PRK13524"
                     /db_xref="CDD:237410"
     gene            694394..695596
                     /gene="fes"
                     /locus_tag="ECs_0624"
                     /db_xref="GeneID:916983"
     CDS             694394..695596
                     /gene="fes"
                     /locus_tag="ECs_0624"
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin/ferrienterobactin esterase"
                     /protein_id="NP_308651.2"
                     /db_xref="GeneID:916983"
                     /translation="MTALKVGSESWWQSKHGPEWQRLNDEMFEVTFWWRDPQGSEEYS
                     TIKRVWIYITGVTDHHQNSQPQSMQRIAGTDVWQWTTQLNANWRGSYCFIPTERDDIF
                     SAPSPDRLELREGWRKLLPQAIADPLNPQSWKGGRGHAVSALEMPQAPLQPGWDCPQA
                     PEIPAKEIIWKSERLKNSRRVWIFTTGDVTAEERPLAVLLDGEFWAQSMPVWPVLISL
                     THRQQLPPAVYVLIDAIDTTHRAHELPCNADFWLAVQQELLPLVKAIAPFSDRADRTV
                     VAGQSFGGLSALYAGLHWPERFGCVLSQSGSYWWPHRGGQQEGVLLEKLKAGEVSAEG
                     LRIVLEAGIREPMIMRANQALYAQLHPIKESIFWRQVDGGHDALCWRGGLMQGLIDLW
                     QPLFHDRS"
     misc_feature    694394..695578
                     /gene="fes"
                     /locus_tag="ECs_0624"
                     /note="enterobactin/ferric enterobactin esterase;
                     Provisional; Region: PRK10439"
                     /db_xref="CDD:236695"
     gene            695599..695817
                     /gene="ybdZ"
                     /locus_tag="ECs_5381"
                     /db_xref="GeneID:62676058"
     CDS             695599..695817
                     /gene="ybdZ"
                     /locus_tag="ECs_5381"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_009502592.1"
                     /db_xref="GeneID:62676058"
                     /translation="MAFSNPFDDPQGVFYILRNAQGQFSLWPQQCALPAGWDIVCQPQ
                     SQESCQQWLEVHWRTLTPANFTQLQEAQ"
     misc_feature    695602..695814
                     /gene="ybdZ"
                     /locus_tag="ECs_5381"
                     /note="Uncharacterized conserved protein YbdZ, MbtH family
                     [Function unknown]; Region: MbtH; COG3251"
                     /db_xref="CDD:225790"
     gene            695814..699695
                     /gene="entF"
                     /locus_tag="ECs_0625"
                     /db_xref="GeneID:916984"
     CDS             695814..699695
                     /gene="entF"
                     /locus_tag="ECs_0625"
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin synthase multienzyme complex
                     component"
                     /protein_id="NP_308652.1"
                     /db_xref="GeneID:916984"
                     /translation="MSQHLPLVAAQPGIWMAEKLSELPSAWSVAHYVELTGEVDAPLL
                     ARAVVAGLAQADTLRMRFTEDNGEVWQWVDDALIFELPEIIDLRTNIDPHGTAQALMQ
                     ADLQQDLRVDSGKPLVFHQLIQVADNRWYWYQRYHHLLVDGFSFPAITRQIANIYCAL
                     LRGEQTPASPFTPFADVVEEYQQYRESEAWQRDAAFWAEQRRQLPPPASLSPAPLAGR
                     SASADILRLKLEFTDGEFRQLATQLSGVQRTDLALALAAFWLGRLCNRMDYAAGFIFM
                     RRLGSAALTATGPVLNVLPLGIHIAAQETLPELATRLAAQLKKMRRHQRYDAEQIVRD
                     SGRAAGDEPLFGPVLNIKVFDYQLDIPGVQAQTHTLATGPVNDLELALFPDEHGDLSI
                     EILANKQHYDEPTLIQHAERLKMLIAQFAADPALLCGDVDIMLPGEYAQLAQINATQV
                     EIPETTLSALVAEQAAKTPDAPALADARYQFSYREMREQVVALANLLREHGVKPGDSV
                     AVALPRSVFLTLALHAIVEAGAAWLPLDTGYPDDRLKMMLEDARPSLLITTDDQLPRF
                     ADVPDLTNLCYNAPLTPQGSAPLQLSQPHHTAYIIFTSGSTGRPKGVMVGQTAIVNRL
                     LWMQNHYPLTGEDVVAQKTPCSFDVSVWEFFWPFIAGAKLVMAEPEAHRDPLAMQQFF
                     AEYGVTTTHFVPSMLAAFVASLTPQTARQNCATLKQVFCSGEALPADLCREWQQLTGA
                     PLHNLYGPTEAAVDVSWYPAFGEELAQVRGSSVPIGYPVWNTGLRILDAMMHPVPPGV
                     AGDLYLTGIQLAQGYLGRPDLTASRFIADPFVPGERMYRTGDVARWLDNGAVEYLGRS
                     DDQLKIRGQRIELGEIDRVMQALPDVEQAVTHACVINQAAATGGDARQLVGYLVSQSG
                     LPLDTSALQAQLRETLPPHMAPVVLLQLPQLPLSANGKLDRKALPLPELKAQTPGRAP
                     KAGSETIIAAAFASLLGCDVQDADADFFALGGHSLLAMKLAAQLSRQFARQVTPGQVM
                     VASTVAKLATIIDGEEDSSRRMGFETILPLREGNGPTLFCFHPASGFAWQFSVLSRYL
                     DPLWSIIGIQSPRPHGPMQTATNLDEVCEAHLATLLEQQPHGPYYLLGYSLGGTLAQG
                     IAARLRARGEQVAFLGLLDTWPPETQNWQEKEANGLDPEVLAEINREREAFLAAQQGS
                     TSTELFTTIEGNYADAVRLLTTAHSVPFDGKATLFVAERTLQEGMSPERAWSPWIAEL
                     DIYRQDCAHVDIISPGAFEKIGPIIRATLNR"
     misc_feature    695814..699689
                     /gene="entF"
                     /locus_tag="ECs_0625"
                     /note="enterobactin non-ribosomal peptide synthetase EntF;
                     Region: entF; PRK10252"
                     /db_xref="CDD:236668"
     gene            699911..701044
                     /gene="fepE"
                     /locus_tag="ECs_0626"
                     /db_xref="GeneID:916985"
     CDS             699911..701044
                     /gene="fepE"
                     /locus_tag="ECs_0626"
                     /codon_start=1
                     /transl_table=11
                     /product="regulator of length of O-antigen component of
                     lipopolysaccharide chains"
                     /protein_id="NP_308653.1"
                     /db_xref="GeneID:916985"
                     /translation="MSSLNIKQGSDAHFPDYPLASPSNNEIDLLNLISVLWRAKKTVM
                     AVVFAFACAGLLISFILPQKWTSAAVVTPPEPVQWQELEKTFTKLRVLDLDIKIDRTE
                     AFNLFIKKFQSVSLLEEYLRSSPYVMDQLKEAKIDELDLHRAIVALSEKMKAVDDNAS
                     KKKDEPSLYTSWTLSFTAPTSEEAQTVLSGYIDYISALVVKESIENVRNKLEIKTQFE
                     KEKLAQDRIKMKNQLDANIQRLNYSLDIANAAGIKKPVYSNGQAVKDDPDFSISLGAD
                     GIERKLEIEKAVTDVAELNGELRNRQYLVEQLTKANINDVNFTPFKYQLSPSLPVKKD
                     GPGKAIIVILSALIGGMVACGSVLLRYAMASRKQDAMMADHLV"
     misc_feature    699911..701041
                     /gene="fepE"
                     /locus_tag="ECs_0626"
                     /note="LPS O-antigen length regulator; Provisional;
                     Region: PRK10381"
                     /db_xref="CDD:182422"
     gene            complement(701041..701856)
                     /gene="fepC"
                     /locus_tag="ECs_0627"
                     /db_xref="GeneID:916986"
     CDS             complement(701041..701856)
                     /gene="fepC"
                     /locus_tag="ECs_0627"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrienterobactin ABC transporter ATPase"
                     /protein_id="NP_308654.1"
                     /db_xref="GeneID:916986"
                     /translation="MTESVARLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGC
                     GKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQNATTLGDITVQELV
                     ARGRYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQ
                     ETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALR
                     EGKIVAQGAPKEIVTAELIERIYGLRCMIIDDPVAGTPLVVPLGRTAPSTANS"
     misc_feature    complement(701062..701856)
                     /gene="fepC"
                     /locus_tag="ECs_0627"
                     /note="iron-enterobactin ABC transporter ATP-binding
                     protein; Region: PRK10253"
                     /db_xref="CDD:182336"
     gene            complement(701853..702845)
                     /gene="fepG"
                     /locus_tag="ECs_0628"
                     /db_xref="GeneID:916987"
     CDS             complement(701853..702845)
                     /gene="fepG"
                     /locus_tag="ECs_0628"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter permease"
                     /protein_id="NP_308655.1"
                     /db_xref="GeneID:916987"
                     /translation="MIYVSRRLLITCLLLISACVVAGIWGLRSGAVTLEISQVFAALM
                     GDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWS
                     GVLVAMVLFGQDLTAIALAAMVGGIITSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA
                     FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLE
                     MGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTARW
                     GLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESRKK"
     misc_feature    complement(701856..702845)
                     /gene="fepG"
                     /locus_tag="ECs_0628"
                     /note="iron-enterobactin ABC transporter permease; Region:
                     PRK10440"
                     /db_xref="CDD:182463"
     misc_feature    complement(order(702021..702023,702042..702044,
                     702165..702173,702177..702194,702198..702203,
                     702207..702215,702219..702224,702585..702593,
                     702603..702605))
                     /gene="fepG"
                     /locus_tag="ECs_0628"
                     /note="ABC-ATPase subunit interface [active]"
                     /db_xref="CDD:119348"
     misc_feature    complement(order(701877..701879,701886..701891,
                     701898..701900,701907..701912,701919..701921,
                     702072..702074,702300..702302,702309..702314,
                     702348..702350,702354..702359,702366..702368,
                     702375..702380,702387..702392,702399..702404,
                     702408..702410,702567..702569,702582..702584,
                     702588..702590))
                     /gene="fepG"
                     /locus_tag="ECs_0628"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119348"
     misc_feature    complement(order(701928..701930,701952..701954,
                     702084..702086,702096..702098,702270..702272,
                     702348..702350))
                     /gene="fepG"
                     /locus_tag="ECs_0628"
                     /note="putative PBP binding regions [active]"
                     /db_xref="CDD:119348"
     gene            complement(702842..703846)
                     /gene="fepD"
                     /locus_tag="ECs_0629"
                     /db_xref="GeneID:916988"
     CDS             complement(702842..703846)
                     /gene="fepD"
                     /locus_tag="ECs_0629"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrienterobactin ABC transporter permease"
                     /protein_id="NP_308656.1"
                     /db_xref="GeneID:916988"
                     /translation="MSGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEAF
                     SGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGAS
                     FAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAA
                     VLEGLTSGIALLNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALN
                     SLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGA
                     DHRWSLPVTLLATPALLLFADIIGRVIVPGELRVSVVSAFIGAPVLIFLVRRKTRGGA
                     "
     misc_feature    complement(702845..703846)
                     /gene="fepD"
                     /locus_tag="ECs_0629"
                     /note="Fe(3+)-siderophore ABC transporter permease;
                     Region: PRK10441"
                     /db_xref="CDD:182464"
     misc_feature    complement(order(703013..703015,703034..703036,
                     703157..703165,703169..703186,703190..703195,
                     703199..703207,703211..703216,703583..703591,
                     703601..703603))
                     /gene="fepD"
                     /locus_tag="ECs_0629"
                     /note="ABC-ATPase subunit interface [active]"
                     /db_xref="CDD:119348"
     misc_feature    complement(order(702869..702871,702878..702883,
                     702890..702892,702899..702904,702911..702913,
                     703064..703066,703292..703294,703301..703306,
                     703337..703339,703343..703348,703355..703357,
                     703364..703369,703376..703381,703388..703393,
                     703397..703399,703565..703567,703580..703582,
                     703586..703588))
                     /gene="fepD"
                     /locus_tag="ECs_0629"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:119348"
     misc_feature    complement(order(702920..702922,702944..702946,
                     703076..703078,703088..703090,703262..703264,
                     703337..703339))
                     /gene="fepD"
                     /locus_tag="ECs_0629"
                     /note="putative PBP binding regions [active]"
                     /db_xref="CDD:119348"
     gene            703957..705207
                     /gene="entS"
                     /locus_tag="ECs_0630"
                     /db_xref="GeneID:916989"
     CDS             703957..705207
                     /gene="entS"
                     /locus_tag="ECs_0630"
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin exporter"
                     /protein_id="NP_308657.1"
                     /db_xref="GeneID:916989"
                     /translation="MNKQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLGVAVPVQI
                     QMMTHSTWQVGLSVTLTGGAMFVGLMVGGVLADRYERKKVILLARGTCGIGFIGLCLN
                     ALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSV
                     ISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPPPPQPREHPLKSLLAGFR
                     FLLASPLVGGIALLGGLLTMASAVRVLYPALADNWQMSAAQIGFLYAAIPLGAAIGAL
                     TSGKLAHSARPGLLMLLSTLGSFLAIGLFGLMPMWILGVVCLALFGWLSAVSSLLQYT
                     MLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGGLGAMMTPVASASASGFGLLIIGV
                     LLLLVLVELRRFRQTPPQVTASDG"
     misc_feature    703957..705204
                     /gene="entS"
                     /locus_tag="ECs_0630"
                     /note="enterobactin transporter EntS; Region: PRK10489"
                     /db_xref="CDD:236700"
     gene            complement(705211..706167)
                     /gene="fepB"
                     /locus_tag="ECs_0631"
                     /db_xref="GeneID:916990"
     CDS             complement(705211..706167)
                     /gene="fepB"
                     /locus_tag="ECs_0631"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrienterobactin ABC transporter periplasmic
                     binding protein"
                     /protein_id="NP_308658.1"
                     /db_xref="GeneID:916990"
                     /translation="MRLAPLYRNALLLTGLLFSGIAAVQAADWPRQITDSRGTHTLES
                     QPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQRLY
                     IGEPSTEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKSWQALLTQLG
                     EITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLWTPESAQGQM
                     LEQLGFTLAKLPAGLNASQSQGKRHDIIQLGGENLAAGLNGESLFLFAGDQKDADAIY
                     ANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQVLERLKALF"
     misc_feature    complement(705214..706167)
                     /gene="fepB"
                     /locus_tag="ECs_0631"
                     /note="ABC-type Fe2+-enterobactin transport system,
                     periplasmic component [Inorganic ion transport and
                     metabolism]; Region: FepB; COG4592"
                     /db_xref="CDD:226958"
     gene            706356..707531
                     /gene="entC"
                     /locus_tag="ECs_0632"
                     /db_xref="GeneID:916991"
     CDS             706356..707531
                     /gene="entC"
                     /locus_tag="ECs_0632"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase 1"
                     /protein_id="NP_308659.1"
                     /db_xref="GeneID:916991"
                     /translation="MDTSLAEEVQQTMATLAPNRFFFMSPYRSFTTSGCFARFDEPAV
                     NGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEK
                     QASARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDA
                     AIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARR
                     QPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWH
                     LATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWC
                     DSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH"
     misc_feature    706356..707528
                     /gene="entC"
                     /locus_tag="ECs_0632"
                     /note="isochorismate synthase EntC; Provisional; Region:
                     PRK15016"
                     /db_xref="CDD:184977"
     gene            707541..709151
                     /gene="entE"
                     /locus_tag="ECs_0633"
                     /db_xref="GeneID:916992"
     CDS             707541..709151
                     /gene="entE"
                     /locus_tag="ECs_0633"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-dihydroxybenzoate-AMP ligase component of
                     enterobactin synthase multienzyme complex"
                     /protein_id="NP_308660.1"
                     /db_xref="GeneID:916992"
                     /translation="MSIPFTRWPEEFARRYREKGYWQDLPLTDILTRHAASDSIAVID
                     GERQLSYRELNQAADNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVL
                     ALFSHQRSELNAYASQIEPALLIADRQHALFSGDDFLNTFVAEHSSIRVVQLLNDSGE
                     HNLQDAINHPADGFTATPSPADEVVYFQLSGGTTGTPKLIPRTHNDYYYSVRRSVEIC
                     QFTQQTRYLCAIPAAHNYAMSSPGSLGVFLAGGTVVLAADPSATLCFPLIEKHQINVT
                     ALVPPAVSLWLQALTEGESRAQLASLKLLQVGGARLSATLAARIPAEIGCQLQQVFGM
                     AEGLVNYTRLDDSAEKIIHTQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFR
                     GYYKSPQHNASAFDANGFYCSGDLISIDPEGYITVQGREKDQINRGGEKIAAEEIENL
                     LLRHPAVIYAALVSMEDELMGEKSCAYLVVKEPLRAVQVRRFLREQGIAEFKLPDRVE
                     CVDSLPLTAVGKVDKKQLRQWLASRASA"
     misc_feature    707541..709148
                     /gene="entE"
                     /locus_tag="ECs_0633"
                     /note="(2,3-dihydroxybenzoyl)adenylate synthase; Region:
                     entE; PRK10946"
                     /db_xref="CDD:236803"
     gene            709165..710022
                     /gene="entB"
                     /locus_tag="ECs_0634"
                     /db_xref="GeneID:916993"
     CDS             709165..710022
                     /gene="entB"
                     /locus_tag="ECs_0634"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase"
                     /protein_id="NP_308661.1"
                     /db_xref="GeneID:916993"
                     /translation="MAIPKLQAYALPESHDIPQNKVDWAFEPQRAALLIHDMQDYFVS
                     FWGENCPMMEQVIANIAALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRS
                     PEQQKVVDRLTPDADDTVLVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTT
                     ATDAFMRDIKPFMVADALADFSRDEHLMSLKYVAGRSGRVVMTEELLPAPIPASKAAL
                     REVILPLLDESDEPFDDDNLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAW
                     WKLLSREVK"
     misc_feature    709165..709809
                     /gene="entB"
                     /locus_tag="ECs_0634"
                     /note="Isochorismate hydrolase [Secondary metabolites
                     biosynthesis, transport and catabolism]; Region: EntB;
                     COG1535"
                     /db_xref="CDD:224452"
     misc_feature    709810..710019
                     /gene="entB"
                     /locus_tag="ECs_0634"
                     /note="Aryl carrier domain [Secondary metabolites
                     biosynthesis, transport and catabolism]; Region: DhbB2;
                     COG3433"
                     /db_xref="CDD:225967"
     gene            710022..710768
                     /gene="entA"
                     /locus_tag="ECs_0635"
                     /db_xref="GeneID:916994"
     CDS             710022..710768
                     /gene="entA"
                     /locus_tag="ECs_0635"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase"
                     /protein_id="NP_308662.1"
                     /db_xref="GeneID:916994"
                     /translation="MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFAQEQY
                     PFATEVMDVADAAQVAQVCQRLLAETERLDVLVNAAGILRMGATDQLSKEDWQQTFAV
                     NVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL
                     ELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEI
                     ANTILFLASDLASHITLQDIVVDGGSTLGA"
     misc_feature    710022..710765
                     /gene="entA"
                     /locus_tag="ECs_0635"
                     /note="2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated;
                     Region: PRK08220"
                     /db_xref="CDD:236190"
     gene            710771..711184
                     /gene="entH"
                     /locus_tag="ECs_0636"
                     /db_xref="GeneID:916995"
     CDS             710771..711184
                     /gene="entH"
                     /locus_tag="ECs_0636"
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin synthesis proofreading
                     thioesterase"
                     /protein_id="NP_308663.1"
                     /db_xref="GeneID:916995"
                     /translation="MIWKRHLTLDELNATSDNTMVAHLGIVYTRLGDDVLEAEMPVDI
                     RTHQPFGLLHGGASAALAETLGSMAGFMMTRDGQCVVGTELNATHHRPVSEGKVRGVC
                     QPLHLGRQNQSWEIVVFDEQGRRCCTCRLGTAVLG"
     misc_feature    710771..711181
                     /gene="entH"
                     /locus_tag="ECs_0636"
                     /note="proofreading thioesterase EntH; Region: PRK10254"
                     /db_xref="CDD:182337"
     misc_feature    order(710927..710929,711014..711016,711035..711046)
                     /gene="entH"
                     /locus_tag="ECs_0636"
                     /note="CoenzymeA binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239527"
     misc_feature    order(710930..710932,710936..710938,710945..710947,
                     711017..711031,711035..711037)
                     /gene="entH"
                     /locus_tag="ECs_0636"
                     /note="subunit interaction site [polypeptide binding];
                     other site"
                     /db_xref="CDD:239527"
     misc_feature    order(710933..710935,710957..710962,710969..710974,
                     711014..711016)
                     /gene="entH"
                     /locus_tag="ECs_0636"
                     /note="PHB binding site [active]"
                     /db_xref="CDD:239527"
     gene            711365..713470
                     /gene="cstA"
                     /locus_tag="ECs_0637"
                     /db_xref="GeneID:916996"
     CDS             711365..713470
                     /gene="cstA"
                     /locus_tag="ECs_0637"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein involved in peptide
                     utilization"
                     /protein_id="NP_308664.1"
                     /db_xref="GeneID:916996"
                     /translation="MNKSGKYLVWTVLSVMGAFALGYIALNRGEQINALWIVVASVCI
                     YLIAYRFYGLYIAKNVLAVDPTRMTPAVRHNDGLDYVPTDKKVLFGHHFAAIAGAGPL
                     VGPVLAAQMGYLPGMIWLLAGVVLAGAVQDFMVLFVSTRRDGRSLGELVKEEMGPTAG
                     VIALVACFMIMVIILAVLAMIVVKALTHSPWGTYTVAFTIPLALFMGIYLRYLRPGRI
                     GEVSVIGLVFLIFAIISGGWVAESPTWAPYFDFTGVQLTWMLVGYGFVAAVLPVWLLL
                     APRDYLSTFLKIGTIVGLAVGILIMRPTLTMPALTKFVDGTGPVWTGNLFPFLFITIA
                     CGAVSGFHALISSGTTPKMLANEGQACFIGYGGMLMESFVAIMALVSACIIDPGVYFA
                     MNSPMAVLAPAGTADVVASAAQVVSSWGFAITPDTLNQIASEVGEQSIISRAGGAPTL
                     AVGMAYILHGALGGMMDVAFWYHFAILFEALFILTAVDAGTRAARFMLQDLLGVVSPG
                     LKRTDSLPANLLATALCVLAWGYFLHQGVVDPLGGINTLWPLFGIANQMLAGMALMLC
                     AVVLFKMKRQRYAWVALVPTAWLLICTLTAGWQKAFSPDAKVGFLAIANKFQAMIDSG
                     NIPSQYTESQLAQLVFNNRLDAGLTIFFMVVVVVLALFSIKTALAALKEPKPTAKETP
                     YEPMPENVEEIVVQAKGAH"
     misc_feature    711365..713467
                     /gene="cstA"
                     /locus_tag="ECs_0637"
                     /note="carbon starvation protein CstA; Region: PRK15015"
                     /db_xref="CDD:184976"
     gene            713652..713849
                     /gene="ybdD"
                     /locus_tag="ECs_5382"
                     /db_xref="GeneID:62676059"
     CDS             713652..713849
                     /gene="ybdD"
                     /locus_tag="ECs_5382"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_009502593.1"
                     /db_xref="GeneID:62676059"
                     /translation="MFDSLAKAGKYLGQAAKLMIGMPDYDNYVEHMRVNHPDQTPMTY
                     EEFFRERQDARYGGKGGARCC"
     misc_feature    713652..713846
                     /gene="ybdD"
                     /locus_tag="ECs_5382"
                     /note="Uncharacterized short protein YbdD, DUF466 family
                     [Function unknown]; Region: YbdD; COG2879"
                     /db_xref="CDD:225434"
     gene            complement(713859..714947)
                     /gene="ybdH"
                     /locus_tag="ECs_0638"
                     /db_xref="GeneID:916997"
     CDS             complement(713859..714947)
                     /gene="ybdH"
                     /locus_tag="ECs_0638"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="NP_308665.1"
                     /db_xref="GeneID:916997"
                     /translation="MPHNPIRVVVGPANYFSHPGSFNHLHDFFTDEQLSRAVWIYGVR
                     AIAAAQTKLPPAFGLPGAKHILFRGHCSESDVQQLAAESGDDRSVVIGVGGGALLDTA
                     KALARRLGLPFVAAPTIAATCAAWTPLSVWYNDAGQALHYEIFDDANFMVLVEPEIIL
                     NAPQQYLLAGIGDTLAKWYEAVVLAPQPETLPLTVRLGINNAQAIRDVLLNSSEQALA
                     DQQNQQLTQSFCDVVDAIIAGGGMVGGLGDRFTRVAAAHAVHNGLTVLPQTEKFLHGT
                     KVAYGILVQSALLGQDDVLAQLTGAYQRFHLPTTLAELEVDINNQAEIDKVIAHTLRP
                     VESIHYLPVTLTPDTLRAAFEKVESFKA"
     misc_feature    complement(713862..714947)
                     /gene="ybdH"
                     /locus_tag="ECs_0638"
                     /note="putative oxidoreductase; Provisional; Region:
                     PRK10586"
                     /db_xref="CDD:182570"
     misc_feature    complement(order(714126..714128,714165..714167,
                     714177..714179,714417..714419,714429..714431,
                     714450..714452,714474..714476,714525..714530,
                     714585..714587,714591..714596,714639..714641,
                     714648..714650,714657..714665,714822..714824))
                     /gene="ybdH"
                     /locus_tag="ECs_0638"
                     /note="putative active site [active]"
                     /db_xref="CDD:341451"
     misc_feature    complement(order(714126..714128,714474..714476,
                     714579..714581,714585..714587,714591..714596,
                     714657..714665,714822..714824))
                     /gene="ybdH"
                     /locus_tag="ECs_0638"
                     /note="putative NAD binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:341451"
     misc_feature    complement(order(714126..714128,714177..714179,
                     714429..714431))
                     /gene="ybdH"
                     /locus_tag="ECs_0638"
                     /note="putative metal binding site [ion binding]; other
                     site"
                     /db_xref="CDD:341451"
     gene            715056..716216
                     /gene="ybdL"
                     /locus_tag="ECs_0639"
                     /db_xref="GeneID:916998"
     CDS             715056..716216
                     /gene="ybdL"
                     /locus_tag="ECs_0639"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine aminotransferase"
                     /protein_id="NP_308666.1"
                     /db_xref="GeneID:916998"
                     /translation="MTNNPLIPQSKLPQLGTTIFTQMSALAQQHQAINLSQGFPDFDG
                     PRYLQERLAYHVAQGANQYAPMTGVQALREAIAQKTERLYGYQPDADSDITVTAGATE
                     ALYAAITALVRNGDEVICFDPSYDSYAPAIALSGGIVKRMALQPPHFRVDWQEFAALL
                     SERTRLVILNTPHNPSATVWQQADFAALWQAIAGHEIFVISDEVYEHINFSQQGHASV
                     LAHPQLRERAVAVSSFGKTYHMTGWKVGYCVAPAPISAEIRKVHQYLTFSVNTPAQLA
                     IADMLRAEPEHYLALPDFYRQKRDILVNALNESRLEILPCEGTYFLLVDYSAVSTLDD
                     VEFCQWLTREHGVAAIPLSVFCADPFPHKLIRLCFAKKESTLLAAAERLRQL"
     misc_feature    715056..716213
                     /gene="ybdL"
                     /locus_tag="ECs_0639"
                     /note="methionine aminotransferase; Validated; Region:
                     PRK09082"
                     /db_xref="CDD:181642"
     gene            complement(716217..716846)
                     /gene="ybdM"
                     /locus_tag="ECs_0640"
                     /db_xref="GeneID:916999"
     CDS             complement(716217..716846)
                     /gene="ybdM"
                     /locus_tag="ECs_0640"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="NP_308667.1"
                     /db_xref="GeneID:916999"
                     /translation="MGDTMQQRLTQDLTQFLASLPEDDRINAINEIRMAIHQVSPFRE
                     EPVDCVLWVKNSQLMPNDYNPNNVAPPEKKLLKKSIEIDGFTQPIVVTHTDKNALEIV
                     DGFHRHEIGKGSSSLKLRLKGYLPVTCLEGTRNQRIAATIRHNRARGRHQITAMSEIV
                     RELSQLGWDDNKIGKELGMDSDEVLRLKQINGLQELFADRQYSRAWTVK"
     misc_feature    complement(716412..716711)
                     /gene="ybdM"
                     /locus_tag="ECs_0640"
                     /note="immunoglobulin-binding regulator IbrB activates eib
                     genes; Region: IbrB_like; cd16397"
                     /db_xref="CDD:319255"
     gene            complement(716819..718039)
                     /gene="ybdN"
                     /locus_tag="ECs_0641"
                     /db_xref="GeneID:917000"
     CDS             complement(716819..718039)
                     /gene="ybdN"
                     /locus_tag="ECs_0641"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="NP_308668.1"
                     /db_xref="GeneID:917000"
                     /translation="MSIYKIPLPLNILEAARERITWTLNTLPRVCVSFSGGKDSGLML
                     HLTAELARQMGKKICVLFIDWEAQFSCTINYVQSLRELYTDVIEEFYWVALPLTTQNS
                     LSQYQPEWQCWEPDVEWVRQPPQDAITDPDFFCFYQPGMTFEQFVREFAEWFSQKRPA
                     AMMIGIRADESYNRFVAIASLNKQRFADDKPWTTAAPGGHSWYIYPIYDWKVADIWTW
                     YANHQSLCNPLYNLMYQAGVPLRHMRICEPFGPEQRQGLWLYHVIEPDRWAAMCARVS
                     GVKSGGIYAGHDNHFYGHRKILKPEHLDWQEYALLLLNSMPEKTAEHYRNKIAIYLHW
                     YQKKGIEVPQTQQGDIGAKDIPSWRRICKVLLNNDYWCRALSFSPTKAKNYQRYNERI
                     KGKRQEWGILCNND"
     misc_feature    complement(716840..718039)
                     /gene="ybdN"
                     /locus_tag="ECs_0641"
                     /note="Predicted phosphoadenosine phosphosulfate
                     sulfurtransferase, contains C-terminal DUF3440 domain
                     [General function prediction only]; Region: YbdN; COG3969"
                     /db_xref="CDD:226478"
     gene            complement(718186..719088)
                     /gene="ybdO"
                     /locus_tag="ECs_0642"
                     /db_xref="GeneID:917001"
     CDS             complement(718186..719088)
                     /gene="ybdO"
                     /locus_tag="ECs_0642"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_308669.1"
                     /db_xref="GeneID:917001"
                     /translation="MTNLYDLKKFDLNLLVIFECIYQHLSISKAAESLYITPSAVSQS
                     LQRLRAQFNDPLFIRSGKGIAPTTTGLNLHHHLEKNLRGLEQTINIVNKSELKKNFII
                     HGPQLISCSNNSMLIRCLRQDSSVEIECHDILMSAENAEELLVHRKADLVITQMPVIS
                     RSVICMPLHTIRNTLICSNRHPRITDNSTYEQIMAEEFTQLISKSAGVDDIQMEIDER
                     FMNRKISFRGSSLLTIINSIAVTDLLGIVPYELYNSHRDFLNLKEIKLEHPLPSIKLY
                     ISYNKSSLNNLVFSRFIDRLNECF"
     misc_feature    complement(718189..719070)
                     /gene="ybdO"
                     /locus_tag="ECs_0642"
                     /note="DNA-binding transcriptional regulator; Region:
                     PRK11482"
                     /db_xref="CDD:183159"
     gene            complement(719298..720044)
                     /gene="dsbG"
                     /locus_tag="ECs_0643"
                     /db_xref="GeneID:917002"
     CDS             complement(719298..720044)
                     /gene="dsbG"
                     /locus_tag="ECs_0643"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein"
                     /protein_id="NP_308670.3"
                     /db_xref="GeneID:917002"
                     /translation="MLKKILLLALLPAIAFAEELPAPVKAIEKQGITIIKTFDAPGGM
                     KGYLGKYQDMGVTIYLTPDGKHAISGYMYNEKGENLSNTLIEKEIYAPAGREMWQRME
                     QSHWLLDGKKDAPVIVYVFADPFCPYCKQFWQQARPWVDSGKVQLRTLLVGVIKPESP
                     ATAAAILASKDPAKTWQEYEASGGKLKLNVPANVSTEQMKVLSDNEKLMDDLGANVTP
                     AIYYMSKENTLQQAVGLPDQKTLNIIMGNK"
     misc_feature    complement(719301..719999)
                     /gene="dsbG"
                     /locus_tag="ECs_0643"
                     /note="disulfide isomerase/thiol-disulfide oxidase;
                     Provisional; Region: dsbG; PRK11657"
                     /db_xref="CDD:183262"
     gene            720416..720979
                     /gene="ahpC"
                     /locus_tag="ECs_0644"
                     /db_xref="GeneID:917003"
     CDS             720416..720979
                     /gene="ahpC"
                     /locus_tag="ECs_0644"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase"
                     /protein_id="NP_308671.1"
                     /db_xref="GeneID:917003"
                     /translation="MSLINTKIKPFKNQAFKNGEFIEITEKDTEGRWSVFFFYPADFT
                     FVCPTELGDVADHYEELQKLGVDVYAVSTDTHFTHKAWHSSSETIAKIKYAMIGDPTG
                     ALTRNFDNMREDEGLADRATFVVDPQGIIQAIEVTAEGIGRDASDLLRKIKAAQYVAS
                     HPGEVCPAKWKEGEATLAPSLDLVGKI"
     misc_feature    720416..720976
                     /gene="ahpC"
                     /locus_tag="ECs_0644"
                     /note="alkyl hydroperoxide reductase subunit C;
                     Provisional; Region: PRK10382"
                     /db_xref="CDD:182423"
     gene            721078..722673
                     /gene="ahpF"
                     /locus_tag="ECs_0645"
                     /db_xref="GeneID:917004"
     CDS             721078..722673
                     /gene="ahpF"
                     /locus_tag="ECs_0645"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase"
                     /protein_id="NP_308672.1"
                     /db_xref="GeneID:917004"
                     /translation="MMMFKAQEINMLDTNMKTQLKAYLEKLTKPVELIATLDDSAKSA
                     EIKELLAEIAELSDKVTFKEDNSLPVRKPSFLITNPGSNQGPRFAGSPLGHEFTSLVL
                     ALLWTGGHPSKEAQSLLEQIRHIDGDFEFETYYSLSCHNCPDVVQALNLMSVLNPRIK
                     HTAIDGGTFQNEITDRNVMGVPAVFVNGKEFGQGRMTLTEIVAKIDTGAEKRAAEELN
                     KRDAYDVLIVGSGPAGAAAAIYSARKGIRTGLMGERFGGQILDTVDIENYISVPKTEG
                     QKLAGALKVHVDEYDVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIVATGA
                     KWRNMNVPGEDQYRTKGVTYCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVT
                     LLEFAPEMKADQVLQDKLRSLKNVDIILNAQTTEVKGDGSKVVGLEYRDRVSGDIHNI
                     ELAGIFVQIGLLPNTNWLEGAVERNRMGEIIIDAKCETNVKGVFAAGDCTTVPYKQII
                     IATGEGAKASLSAFDYLIRTKTA"
     misc_feature    721108..722670
                     /gene="ahpF"
                     /locus_tag="ECs_0645"
                     /note="alkyl hydroperoxide reductase subunit F;
                     Provisional; Region: PRK15317"
                     /db_xref="CDD:237942"
     gene            complement(722794..723222)
                     /gene="uspG"
                     /locus_tag="ECs_0646"
                     /db_xref="GeneID:917005"
     CDS             complement(722794..723222)
                     /gene="uspG"
                     /locus_tag="ECs_0646"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UP12"
                     /protein_id="NP_308673.1"
                     /db_xref="GeneID:917005"
                     /translation="MYKTIIMPVDVFEMELSDKAVRHAEFLAQDDGVIHLLHVLPGSA
                     SLSLHRFAADVRRFEEHLQHEAEERLQTMVSHFTIDPSRIKQHVRFGSVRDEVNELAE
                     ELGADVVVIGSRNPSISTHLLGSNASSVIRHANLPVLVVR"
     misc_feature    complement(722797..723222)
                     /gene="uspG"
                     /locus_tag="ECs_0646"
                     /note="universal stress protein UspG; Provisional; Region:
                     PRK15456"
                     /db_xref="CDD:185353"
     gene            723443..724681
                     /gene="ybdR"
                     /locus_tag="ECs_0647"
                     /db_xref="GeneID:917006"
     CDS             723443..724681
                     /gene="ybdR"
                     /locus_tag="ECs_0647"
                     /codon_start=1
                     /transl_table=11
                     /product="Zn-dependent NAD(P)-binding oxidoreductase"
                     /protein_id="NP_308674.1"
                     /db_xref="GeneID:917006"
                     /translation="MKALTYHGPHHVQVENVPDPGIEQADDIILRITATAICGSDLHL
                     YRGKIPQVKHGDIFGHEFMGEVVETGKDVKNLQKGDRVVIPFVIACGDCFFCRLQQYA
                     ACENTNAGKGAALNKKQIPAPAALFGYSHLYGGVPGGQAEYVRVPKGNVGPFKVPPLL
                     SDDKALFLSDILPTAWQAAKNAQIQQGSSVAVYGAGPVGLLTIACARLLGAEQIFVVD
                     HHPYRLRFAADRYGAIPINFDEDSDPAQSIIEQTAGHRGVDAVIDAVGFEAKGSTTET
                     VLTNLKLEGSSGKALRQCIAAVRRGGIVSVPGVYAGFIHGFLFGDAFDKGLTFKMGQT
                     HVHAWLGELLPLIEKGLLKPEEIVTHYMPFEEAARGYEIFEKREEECRKVILVPGAQS
                     AEAAQKAVSGLVNAMPGGTI"
     misc_feature    723443..724606
                     /gene="ybdR"
                     /locus_tag="ECs_0647"
                     /note="Glutathione-dependent formaldehyde dehydrogenase
                     related proteins, child 1; Region: FDH_like_1; cd08283"
                     /db_xref="CDD:176243"
     misc_feature    order(723554..723562,723569..723571,723698..723700,
                     723950..723952,723962..723964,724019..724024,
                     724028..724036,724091..724099,724109..724111,
                     724154..724156,724232..724240,724310..724312,
                     724361..724369,724436..724444,724562..724564)
                     /gene="ybdR"
                     /locus_tag="ECs_0647"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:176243"
     misc_feature    order(723554..723556,723560..723562,723620..723622,
                     723950..723952)
                     /gene="ybdR"
                     /locus_tag="ECs_0647"
                     /note="catalytic Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176243"
     misc_feature    order(723710..723715,723719..723721,723728..723730,
                     723752..723754)
                     /gene="ybdR"
                     /locus_tag="ECs_0647"
                     /note="structural Zn binding site [ion binding]; other
                     site"
                     /db_xref="CDD:176243"
     gene            complement(724912..725322)
                     /gene="rnk"
                     /locus_tag="ECs_0649"
                     /db_xref="GeneID:917008"
     CDS             complement(724912..725322)
                     /gene="rnk"
                     /lo