LOCUS       WP_121847868             480 aa            linear   BCT 08-JAN-2025
DEFINITION  NupC/NupG family nucleoside CNT transporter [Euzebyella marina].
ACCESSION   WP_121847868
VERSION     WP_121847868.1
KEYWORDS    RefSeq.
SOURCE      Euzebyella marina
  ORGANISM  Euzebyella marina
            Bacteria; Pseudomonadati; Bacteroidota; Flavobacteriia;
            Flavobacteriales; Flavobacteriaceae; Euzebyella.
REFERENCE   1  (residues 1 to 480)
  AUTHORS   Hirschi,M., Johnson,Z.L. and Lee,S.Y.
  TITLE     Visualizing multistep elevator-like transitions of a nucleoside
            transporter
  JOURNAL   Nature 545 (7652), 66-70 (2017)
   PUBMED   28424521
REFERENCE   2  (residues 1 to 480)
  AUTHORS   Johnson,Z.L., Lee,J.H., Lee,K., Lee,M., Kwon,D.Y., Hong,J. and
            Lee,S.Y.
  TITLE     Structural basis of nucleoside and nucleoside drug selectivity by
            concentrative nucleoside transporters
  JOURNAL   Elife 3, e03604 (2014)
   PUBMED   25082345
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 480)
  AUTHORS   Munch-Petersen,A., Mygind,B., Nicolaisen,A. and Pihl,N.J.
  TITLE     Nucleoside transport in cells and membrane vesicles from
            Escherichia coli K12
  JOURNAL   J Biol Chem 254 (10), 3730-3737 (1979)
   PUBMED   374403
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11449426
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Euzebyella marina"
                     /db_xref="taxon:1761453"
     Protein         1..480
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005337 - nucleoside transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:1901642 - nucleoside transmembrane
                     transport [Evidence IEA]"
                     /calculated_mol_wt=50841
     Region          53..480
                     /region_name="NupC"
                     /note="Nucleoside permease NupC [Nucleotide transport and
                     metabolism]; COG1972"
                     /db_xref="CDD:441575"
ORIGIN      
        1 mnvrlciill alctffpvla qetpapsies ttindiiqas aeivpnqgfs idslwrgimg
       61 mavllviaff csanrkainw ktvgiglslq lliaigvlkv swvqmafeav gevfisilgf
      121 tragskflfe glvvdtntfg yifafqvlpt ivffsaltsl lfylgviqkv vramawllsk
      181 slgisgpesl svagniflgq teapllikay lekmnrseil lvmiggmatv agavlaayig
      241 flggedealq lvfakhllaa svmaapgaiv iskmlypqte svntdvevst ekigsnmlda
      301 iangtteglr lavnvgamll vfvaliamvn gilewtgdlt tingyiaeht aydklsleai
      361 lgtifaplmw ligvnsedtm lmgqllgikl aasefvgyiq laelkdlttg anlrynksvi
      421 matymlcgfa nfasigiqig gigslapgqr ktlsefgmra vlggsiasll satiagmilg
//