LOCUS       WP_129457998             788 aa            linear   BCT 14-JUL-2025
DEFINITION  glycoside hydrolase family 31 protein [Propioniciclava flava].
ACCESSION   WP_129457998
VERSION     WP_129457998.1
KEYWORDS    RefSeq.
SOURCE      Propioniciclava flava
  ORGANISM  Propioniciclava flava
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Propionibacteriales; Propionibacteriaceae; Propioniciclava.
REFERENCE   1  (residues 1 to 788)
  AUTHORS   Lovering,A.L., Lee,S.S., Kim,Y.W., Withers,S.G. and Strynadka,N.C.
  TITLE     Mechanistic and structural analysis of a family 31
            alpha-glycosidase and its glycosyl-enzyme intermediate
  JOURNAL   J Biol Chem 280 (3), 2105-2115 (2005)
   PUBMED   15501829
REFERENCE   2  (residues 1 to 788)
  AUTHORS   Rigden,D.J.
  TITLE     Iterative database searches demonstrate that glycoside hydrolase
            families 27, 31, 36 and 66 share a common evolutionary origin with
            family 13
  JOURNAL   FEBS Lett 523 (1-3), 17-22 (2002)
   PUBMED   12123797
REFERENCE   3  (residues 1 to 788)
  AUTHORS   Davies,G. and Henrissat,B.
  TITLE     Structures and mechanisms of glycosyl hydrolases
  JOURNAL   Structure 3 (9), 853-859 (1995)
   PUBMED   8535779
REFERENCE   4  (residues 1 to 788)
  AUTHORS   Henrissat,B., Callebaut,I., Fabrega,S., Lehn,P., Mornon,J.P. and
            Davies,G.
  TITLE     Conserved catalytic machinery and the prediction of a common fold
            for several families of glycosyl hydrolases
  JOURNAL   Proc Natl Acad Sci U S A 92 (15), 7090-7094 (1995)
   PUBMED   7624375
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 1996 May 28;93(11):5674. doi:
            10.1073/pnas.93.11.5674. PMID: 8643635]
REFERENCE   5  (residues 1 to 788)
  AUTHORS   Henrissat,B.
  TITLE     A classification of glycosyl hydrolases based on amino acid
            sequence similarities
  JOURNAL   Biochem J 280 (Pt 2) (Pt 2), 309-316 (1991)
   PUBMED   1747104
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11572220
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..788
                     /organism="Propioniciclava flava"
                     /db_xref="taxon:2072026"
     Protein         1..788
                     /product="glycoside hydrolase family 31 protein"
                     /EC_number="3.2.1.-"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=86445
     Region          196..500
                     /region_name="GH31_u1"
                     /note="glycosyl hydrolase family 31 (GH31);
                     uncharacterized subgroup; cd06595"
                     /db_xref="CDD:269881"
     Site            order(242,351,389,402,405,438,464)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:269881"
     Region          618..682
                     /region_name="DUF5110"
                     /note="Domain of unknown function (DUF5110); pfam17137"
                     /db_xref="CDD:465360"
ORIGIN      
        1 mpqtprfrpl thplarpdqi vtgehwrvtv ltprllrlew sdsgsfedrp tqvvwhrdlp
       61 aarftatpyg agvrvetdal rldydglpfs aagltvhqhs sqghhtvwhy gdpepvvrpt
      121 rgnmggtart ldevdgaidl gtgvvsalgw atlddsasla ldedgwptpr tgtkdlyffg
      181 hghdsagavr dfyaitgpqp llprwalgnw wsryhpysas eytglmdrfs aegmpfsvav
      241 idmdwhwvel anghgsgwtg fswntdlfpd pdafldglhe rglkvslnlh padgvrsfed
      301 aypalarrlg rdpesgevie favadpefma ayfdtvlhpm edagvdfwwl dwqqgtasal
      361 pgldplwlln hahyfdsare gkrpltfsry agpgshrypv gfsgdtvtsw asldfqpyft
      421 atasnigygw wshdigghmf gtrddemvar wfqlgtfspi nrlhstaspf mgkepwmfgv
      481 eartvmteal rlrhrlvpyl ytmnevahrt gtplvrplyh adpreetafs slntflfgte
      541 llvapvttar drrtlraatt awlpegtwvd ffdgtpysgg rfvtlhrtle rypvlarvga
      601 ivplvggedl sttnpsaltv rvfagadgaf tlyedddaaa pvcartplaw dqasgtftia
      661 pvegdaavlp qgrswtlelv gvapveaash pgsydaatgt lrvevgavdp avgttvrlaa
      721 ppapfvpdad arlfalitql qvgypdkhal waflsqnpdp arrvaglaal piaedikpvi
      781 aevllarl
//