LOCUS WP_155317993 216 aa linear BCT 18-FEB-2025
DEFINITION LexA family transcriptional regulator [Desulfosarcina
alkanivorans].
ACCESSION WP_155317993
VERSION WP_155317993.1
KEYWORDS RefSeq.
SOURCE Desulfosarcina alkanivorans
ORGANISM Desulfosarcina alkanivorans
Bacteria; Pseudomonadati; Thermodesulfobacteriota; Desulfobacteria;
Desulfobacterales; Desulfosarcinaceae; Desulfosarcina.
REFERENCE 1 (residues 1 to 216)
AUTHORS Giese,K.C., Michalowski,C.B. and Little,J.W.
TITLE RecA-dependent cleavage of LexA dimers
JOURNAL J Mol Biol 377 (1), 148-161 (2008)
PUBMED 18234215
REFERENCE 2 (residues 1 to 216)
AUTHORS Erill,I., Campoy,S. and Barbe,J.
TITLE Aeons of distress: an evolutionary perspective on the bacterial SOS
response
JOURNAL FEMS Microbiol Rev 31 (6), 637-656 (2007)
PUBMED 17883408
REFERENCE 3 (residues 1 to 216)
AUTHORS Aravind,L., Anantharaman,V., Balaji,S., Babu,M.M. and Iyer,L.M.
TITLE The many faces of the helix-turn-helix domain: transcription
regulation and beyond
JOURNAL FEMS Microbiol Rev 29 (2), 231-262 (2005)
PUBMED 15808743
REFERENCE 4 (residues 1 to 216)
AUTHORS Rosinski,J.A. and Atchley,W.R.
TITLE Molecular evolution of helix-turn-helix proteins
JOURNAL J Mol Evol 49 (3), 301-309 (1999)
PUBMED 10473770
COMMENT REFSEQ: This record represents a single, non-redundant, protein
sequence which may be annotated on many different RefSeq genomes
from the same, or different, species.
##Evidence-For-Name-Assignment-START##
Evidence Category :: Conserved Domain (CDD)
Evidence Accession :: Domain architecture ID 11715193
Evidence Source :: NCBI SPARCLE
##Evidence-For-Name-Assignment-END##
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..216
/organism="Desulfosarcina alkanivorans"
/db_xref="taxon:571177"
Protein 1..216
/product="LexA family transcriptional regulator"
/EC_number="3.4.21.88"
/GO_function="GO:0003677 - DNA binding [Evidence IEA]"
/GO_function="GO:0003700 - DNA-binding transcription
factor activity [Evidence IEA]"
/GO_function="GO:0004252 - serine-type endopeptidase
activity [Evidence IEA]"
/GO_process="GO:0006282 - regulation of DNA repair
[Evidence IEA]"
/GO_process="GO:0006355 - regulation of DNA-templated
transcription [Evidence IEA]"
/calculated_mol_wt=24270
Region 8..69
/region_name="HTH_XRE"
/note="Helix-turn-helix XRE-family like proteins.
Prokaryotic DNA binding proteins belonging to the
xenobiotic response element family of transcriptional
regulators; cl22854"
/db_xref="CDD:473980"
Region 85..210
/region_name="COG2932"
/note="Phage repressor protein C, contains Cro/C1-type HTH
and peptisase s24 domains [Mobilome: prophages,
transposons]"
/db_xref="CDD:442176"
ORIGIN
1 mnknfqiffd raagalgirs lselaailnv nrssitqark knsvpanwll elfrshglnp
61 dwleggsgpq wlksgdafkn dffpvpkvra rlcagagsfe teariedyys fqtqwlqnkg
121 vkdrmvlmdv sgnsmapeik dgdtvlidqs qtdifagmvy avgvedtimv krlekhprkl
181 vllsdnkayt pifladdemd rvriigkvlw icrelr
//