GenomeNet

Database: RefSeq
Entry: WP_155317993
LinkDB: WP_155317993
Original site: WP_155317993 
LOCUS       WP_155317993             216 aa            linear   BCT 18-FEB-2025
DEFINITION  LexA family transcriptional regulator [Desulfosarcina
            alkanivorans].
ACCESSION   WP_155317993
VERSION     WP_155317993.1
KEYWORDS    RefSeq.
SOURCE      Desulfosarcina alkanivorans
  ORGANISM  Desulfosarcina alkanivorans
            Bacteria; Pseudomonadati; Thermodesulfobacteriota; Desulfobacteria;
            Desulfobacterales; Desulfosarcinaceae; Desulfosarcina.
REFERENCE   1  (residues 1 to 216)
  AUTHORS   Giese,K.C., Michalowski,C.B. and Little,J.W.
  TITLE     RecA-dependent cleavage of LexA dimers
  JOURNAL   J Mol Biol 377 (1), 148-161 (2008)
   PUBMED   18234215
REFERENCE   2  (residues 1 to 216)
  AUTHORS   Erill,I., Campoy,S. and Barbe,J.
  TITLE     Aeons of distress: an evolutionary perspective on the bacterial SOS
            response
  JOURNAL   FEMS Microbiol Rev 31 (6), 637-656 (2007)
   PUBMED   17883408
REFERENCE   3  (residues 1 to 216)
  AUTHORS   Aravind,L., Anantharaman,V., Balaji,S., Babu,M.M. and Iyer,L.M.
  TITLE     The many faces of the helix-turn-helix domain: transcription
            regulation and beyond
  JOURNAL   FEMS Microbiol Rev 29 (2), 231-262 (2005)
   PUBMED   15808743
REFERENCE   4  (residues 1 to 216)
  AUTHORS   Rosinski,J.A. and Atchley,W.R.
  TITLE     Molecular evolution of helix-turn-helix proteins
  JOURNAL   J Mol Evol 49 (3), 301-309 (1999)
   PUBMED   10473770
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11715193
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..216
                     /organism="Desulfosarcina alkanivorans"
                     /db_xref="taxon:571177"
     Protein         1..216
                     /product="LexA family transcriptional regulator"
                     /EC_number="3.4.21.88"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=24270
     Region          8..69
                     /region_name="HTH_XRE"
                     /note="Helix-turn-helix XRE-family like proteins.
                     Prokaryotic DNA binding proteins belonging to the
                     xenobiotic response element family of transcriptional
                     regulators; cl22854"
                     /db_xref="CDD:473980"
     Region          85..210
                     /region_name="COG2932"
                     /note="Phage repressor protein C, contains Cro/C1-type HTH
                     and peptisase s24 domains [Mobilome: prophages,
                     transposons]"
                     /db_xref="CDD:442176"
ORIGIN      
        1 mnknfqiffd raagalgirs lselaailnv nrssitqark knsvpanwll elfrshglnp
       61 dwleggsgpq wlksgdafkn dffpvpkvra rlcagagsfe teariedyys fqtqwlqnkg
      121 vkdrmvlmdv sgnsmapeik dgdtvlidqs qtdifagmvy avgvedtimv krlekhprkl
      181 vllsdnkayt pifladdemd rvriigkvlw icrelr
//
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