LOCUS       WP_193857794             584 aa            linear   BCT 04-JUN-2024
DEFINITION  2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid
            synthase [cf. Phormidesmis sp. LEGE 11477].
ACCESSION   WP_193857794
VERSION     WP_193857794.1
KEYWORDS    RefSeq.
SOURCE      cf. Phormidesmis sp. LEGE 11477
  ORGANISM  cf. Phormidesmis sp. LEGE 11477
            Bacteria; Bacillati; Cyanobacteriota; Cyanophyceae;
            Leptolyngbyales; Leptolyngbyaceae; Phormidesmis.
REFERENCE   1  (residues 1 to 584)
  AUTHORS   Jiang,M., Cao,Y., Guo,Z.F., Chen,M., Chen,X. and Guo,Z.
  TITLE     Menaquinone biosynthesis in Escherichia coli: identification of
            2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate as a
            novel intermediate and re-evaluation of MenD activity
  JOURNAL   Biochemistry 46 (38), 10979-10989 (2007)
   PUBMED   17760421
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00173.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..584
                     /organism="cf. Phormidesmis sp. LEGE 11477"
                     /db_xref="taxon:1828680"
     gene            1..584
                     /gene="menD"
     Protein         1..584
                     /product="2-succinyl-5-enolpyruvyl-6-hydroxy-3-
                     cyclohexene-1-carboxylic-acid synthase"
                     /EC_number="2.2.1.9"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0070204 -
                     2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-
                     carboxylic-acid synthase activity [Evidence IEA]"
                     /GO_process="GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=64323
     Region          6..584
                     /region_name="MenD"
                     /note="2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-
                     carboxylate synthase [Coenzyme transport and metabolism];
                     COG1165"
                     /db_xref="CDD:440779"
ORIGIN      
        1 mpidfrntns lwasvavetl arlglqtail cpgsrstplt fafanhpqie alpildersa
       61 affalgcakr qhrpvaivct sgtaganfyp avieacesgv pllvftadrp pemrdcasgq
      121 tidqinlygg fvkrfvemmv pmadlsmlay lrqtlvsgwe saialqpgpi hfncpfrdpl
      181 ppiaddstrv vkagfdigkf fysvsasatt kvqaflltsl piadwqqfet giivagpadp
      241 sdplsycktv shlsqrlgwp viaeglsplr nysalnlalv stydlilrdr drakklvpqg
      301 viqlgalpts kvlrqwlsmh qpqrwiigpq rnldplhgpt rhltleiaal iqtssavfpi
      361 ensiyqqqwl tyegemrrai rekmaaestl veskvvwlls qhlpeqtplf vansmpvrdl
      421 esfwlpndrq iqpvfsrgan gidgtlstam glahrnrpav llsgdlaflh dtngllntaq
      481 idghltvvli nnggggifem lpvadfsptf ekyfvtpqsv kfsylcqayg ieyrlvqtae
      541 dlvkcievlp kqgirvleig adqhtsvayr qqsvaqrknl lnfl
//