LOCUS       WP_198344353             883 aa            linear   BCT 19-DEC-2020
DEFINITION  valine--tRNA ligase [Mycobacterium dioxanotrophicus].
ACCESSION   WP_198344353
VERSION     WP_198344353.1
KEYWORDS    RefSeq.
SOURCE      Mycobacterium dioxanotrophicus
  ORGANISM  Mycobacterium dioxanotrophicus
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Mycobacteriales; Mycobacteriaceae; Mycobacterium.
REFERENCE   1  (residues 1 to 883)
  AUTHORS   Fukunaga,R. and Yokoyama,S.
  TITLE     Structural basis for non-cognate amino acid discrimination by the
            valyl-tRNA synthetase editing domain
  JOURNAL   J Biol Chem 280 (33), 29937-29945 (2005)
   PUBMED   15970591
REFERENCE   2  (residues 1 to 883)
  AUTHORS   Tardif,K.D. and Horowitz,J.
  TITLE     Functional group recognition at the aminoacylation and editing
            sites of E. coli valyl-tRNA synthetase
  JOURNAL   RNA 10 (3), 493-503 (2004)
   PUBMED   14970394
REFERENCE   3  (residues 1 to 883)
  AUTHORS   Fukai,S., Nureki,O., Sekine,S., Shimada,A., Vassylyev,D.G. and
            Yokoyama,S.
  TITLE     Mechanism of molecular interactions for tRNA(Val) recognition by
            valyl-tRNA synthetase
  JOURNAL   RNA 9 (1), 100-111 (2003)
   PUBMED   12554880
REFERENCE   4  (residues 1 to 883)
  AUTHORS   Hountondji,C., Lazennec,C., Beauvallet,C., Dessen,P.,
            Pernollet,J.C., Plateau,P. and Blanquet,S.
  TITLE     Crucial role of conserved lysine 277 in the fidelity of tRNA
            aminoacylation by Escherichia coli valyl-tRNA synthetase
  JOURNAL   Biochemistry 41 (50), 14856-14865 (2002)
   PUBMED   12475234
REFERENCE   5  (residues 1 to 883)
  AUTHORS   Fukai,S., Nureki,O., Sekine,S., Shimada,A., Tao,J., Vassylyev,D.G.
            and Yokoyama,S.
  TITLE     Structural basis for double-sieve discrimination of L-valine from
            L-isoleucine and L-threonine by the complex of tRNA(Val) and
            valyl-tRNA synthetase
  JOURNAL   Cell 103 (5), 793-803 (2000)
   PUBMED   11114335
REFERENCE   6  (residues 1 to 883)
  AUTHORS   Heck,J.D. and Hatfield,G.W.
  TITLE     Valyl-tRNA synthetase gene of Escherichia coli K12. Primary
            structure and homology within a family of aminoacyl-TRNA
            synthetases
  JOURNAL   J Biol Chem 263 (2), 868-877 (1988)
   PUBMED   3275660
REFERENCE   7  (residues 1 to 883)
  AUTHORS   Hartlein,M., Frank,R. and Madern,D.
  TITLE     Nucleotide sequence of Escherichia coli valyl-tRNA synthetase gene
            valS
  JOURNAL   Nucleic Acids Res 15 (21), 9081-9082 (1987)
   PUBMED   3317277
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF004349.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK05729
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..883
                     /organism="Mycobacterium dioxanotrophicus"
                     /db_xref="taxon:482462"
     Protein         1..883
                     /product="valine--tRNA ligase"
                     /EC_number="6.1.1.9"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /calculated_mol_wt=97959
     Region          8..883
                     /region_name="valS"
                     /note="valyl-tRNA synthetase; Reviewed; PRK05729"
                     /db_xref="CDD:235582"
ORIGIN      
        1 mtstpdnrad alpkswepga veaelyqgwv dagyftadat sdkpaysivl pppnvtgslh
       61 mghaldhtlm dvltrrkrmq gyevlwlpgm dhagiatqtl vekqlaadgk tkedfgreef
      121 vekvwdwkre sggtigaqmr rigdgvdwsr drftmddgls ravrtifkrl fdagliyqae
      181 rlvnwspvle taisdlevky edvegelvsf rygsmsddep hivvattrve tmlgdtaiav
      241 hpdderyrhl vgttlphpft dariiivadt hvdpefgtga vkvtpahdpn dfeiglrhql
      301 pmptimdtkg riadtgtqfd gmdrfearvk vrealaeqgr ivaekrpylh svghsersge
      361 pieprlslqw wvkveslaka agdavrggdt vihppslepr wfawvddmhd wcisrqlwwg
      421 hripiwhgpn getvcvgpde tppegweqdp dvldtwfssa lwpfstmgwp dhtadlakfy
      481 ptsvlvtgyd ilffwvarmm mfgtfvgddp aitlegkrgr qvpfqnvflh glirdefgrk
      541 msksrgngid plewvemfga dalrftlarg aspggdlsig edharasrnf atklfnatrf
      601 almngaapaa lppaaeltda drwilgrlee vraevdeald syqfsracea lyhfawdefc
      661 dwyvelakvq ifgglphtta vlaavldtll kllhpvmpfv tetlwktltg gesaviaawp
      721 qpsgfapdpv aaqritdmqk litevrrfrs dqgladrqkv parlsdiaaa qlseqlpait
      781 slawlteagd gftpsaavev rlsqttvvve vdtsgtvdva aerrrlekdl avaqkematt
      841 aaklgndafl akapaevvdk irgrqqvate everitarla glk
//