LOCUS       WP_210420182             515 aa            linear   BCT 11-JAN-2025
DEFINITION  NupC/NupG family nucleoside CNT transporter [Aquisphaera
            giovannonii].
ACCESSION   WP_210420182
VERSION     WP_210420182.1
KEYWORDS    RefSeq.
SOURCE      Aquisphaera giovannonii
  ORGANISM  Aquisphaera giovannonii
            Bacteria; Pseudomonadati; Planctomycetota; Planctomycetia;
            Isosphaerales; Isosphaeraceae; Aquisphaera.
REFERENCE   1  (residues 1 to 515)
  AUTHORS   Hirschi,M., Johnson,Z.L. and Lee,S.Y.
  TITLE     Visualizing multistep elevator-like transitions of a nucleoside
            transporter
  JOURNAL   Nature 545 (7652), 66-70 (2017)
   PUBMED   28424521
REFERENCE   2  (residues 1 to 515)
  AUTHORS   Johnson,Z.L., Lee,J.H., Lee,K., Lee,M., Kwon,D.Y., Hong,J. and
            Lee,S.Y.
  TITLE     Structural basis of nucleoside and nucleoside drug selectivity by
            concentrative nucleoside transporters
  JOURNAL   Elife 3, e03604 (2014)
   PUBMED   25082345
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 515)
  AUTHORS   Munch-Petersen,A., Mygind,B., Nicolaisen,A. and Pihl,N.J.
  TITLE     Nucleoside transport in cells and membrane vesicles from
            Escherichia coli K12
  JOURNAL   J Biol Chem 254 (10), 3730-3737 (1979)
   PUBMED   374403
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11449426
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..515
                     /organism="Aquisphaera giovannonii"
                     /db_xref="taxon:406548"
     Protein         1..515
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005337 - nucleoside transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:1901642 - nucleoside transmembrane
                     transport [Evidence IEA]"
                     /calculated_mol_wt=54564
     Region          117..515
                     /region_name="NupC"
                     /note="Nucleoside permease NupC [Nucleotide transport and
                     metabolism]; COG1972"
                     /db_xref="CDD:441575"
ORIGIN      
        1 mrrirltltd prrtnrdpgt spagarprvc rpwrvgllll alyqvyapai avaaqgaedg
       61 pptgsaastg taatrpgrpg vtvepgpaev rreyrlkvgs wttrfslpes idladvmdra
      121 rgvlgmlaiv gvavflsedr raisrrivfw gltlqcafav lvlrvpagir amraaggave
      181 svlacamega efvfgkalva pdgpagfvfa frvlptvifv aalfaalyyl hvmqwivrlf
      241 avvmawfmgt sgaeslnvaa slflgqteap ltirpylarl trselltvmt sgmahvsggi
      301 mavyfgygve prhiitavim tapgtillsk lllpetgkpe tlghtrpsse vedanildav
      361 argtrdgltl alniaamlia ilglialinl glgqvgmslq kilgwllapv ayllgvpwed
      421 creiggllgt rtvlneviaf kelgavkgsl yarsfdiasf alcgfanfss igiqlggiga
      481 lvpdrrrdla elgwrallag tmanflsaci agill
//