LOCUS       WP_239176967            1080 aa            linear   BCT 28-MAR-2026
DEFINITION  TIM-barrel domain-containing protein [Actinoplanes octamycinicus].
ACCESSION   WP_239176967
VERSION     WP_239176967.1
KEYWORDS    RefSeq.
SOURCE      Actinoplanes octamycinicus
  ORGANISM  Actinoplanes octamycinicus
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Micromonosporales; Micromonosporaceae; Actinoplanes.
REFERENCE   1  (residues 1 to 1080)
  AUTHORS   Henrissat,B.
  TITLE     Glycosidase families
  JOURNAL   Biochem Soc Trans 26 (2), 153-156 (1998)
   PUBMED   9649738
REFERENCE   2  (residues 1 to 1080)
  AUTHORS   Henrissat,B.
  TITLE     A classification of glycosyl hydrolases based on amino acid
            sequence similarities
  JOURNAL   Biochem J 280 (Pt 2) (Pt 2), 309-316 (1991)
   PUBMED   1747104
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF013239.7
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF01055.33
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1080
                     /organism="Actinoplanes octamycinicus"
                     /db_xref="taxon:135948"
     Protein         1..1080
                     /product="TIM-barrel domain-containing protein"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=116020
     Region          41..>98
                     /region_name="AGL_N"
                     /note="Alpha-glucosidase, N-terminal; pfam16338"
                     /db_xref="CDD:465098"
     Region          219..531
                     /region_name="GH31_u1"
                     /note="glycosyl hydrolase family 31 (GH31);
                     uncharacterized subgroup; cd06595"
                     /db_xref="CDD:269881"
     Site            order(266,371,410,436,439,472,498)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:269881"
     Region          646..709
                     /region_name="DUF5110"
                     /note="Domain of unknown function (DUF5110); pfam17137"
                     /db_xref="CDD:465360"
     Region          <750..>896
                     /region_name="MJ0795"
                     /note="S-layer protein MJ0795, predicted component of type
                     IV pili-like system [General function prediction only];
                     COG1361"
                     /db_xref="CDD:440972"
     Region          867..952
                     /region_name="CBM_2"
                     /note="Starch binding domain; smart01065"
                     /db_xref="CDD:215006"
     Site            order(879..884,910,912)
                     /site_type="other"
                     /note="starch-binding site 2 [chemical binding]"
                     /db_xref="CDD:99886"
ORIGIN      
        1 mvtrlaawva flmllvltpg galaaprapq lhgqtvqagh lrvqvlsptl lrleysaddt
       61 fedrptfnav drdpprtrft astrggelrv ttsavtlrhr ldsgpvtaan tslelrvggr
      121 pvtahpefgn paradalggw yrgldyyagq agpveqlklh pgmlnrggwy llddtatalr
      181 tdagwvaarp artgayqdgy lfgyghdyrr gladlraltg psalppkwaf gtwfskyqay
      241 saedyrtqll pafaennvpl dslvidtdwk apnqwagwnw nstlfpkpee fvdelsrkgi
      301 tttlnvhaai sgddprfaga qatakgkltp atssfapnpy rfdwsdpdqa aawtalhrpf
      361 edqgvrqwwl dyccddsrvt vpgltadswv nelyrrdgea adrrgfalsr igasfpdytt
      421 pgpsgpwaeh rstvhftgdt rpdwatlafa aamtpaeasi gmsyvshdig sfagkhlpdd
      481 lylrwvqlga fqpilrlhsd hgdrlpweya gtvgkpaadf lrlrealvpy lytaarqtyd
      541 tgmpmaraly lqwpeldeay qhdtqyllgd sllvapvttp glsttvpvwf ppgtwtdfft
      601 getfrgpatr tvaatpdhmp vyvraggilp taapapnvaa qpadrltlta yphasgstvv
      661 yddagdglgy rtgqytrtpv rydegrrgae ltvgpatrsr hytvqfagvs rphlvtvagr
      721 rvpftydaak hlisvevtga kaitvrhdgv pltvaqqpav eltltapdgl qsgatsrlvl
      781 aahnagpgti taltgsitap dgwvvtprta ttaaslapga dftvtydvtp tgpsprtaav
      841 tghlayrnpd gsaaslpasl tvpvrpvavt frvlappgtp pdatlhvpgn itelgpwdpg
      901 kvamtnrgng iheatvtvld gtdiqykytr gtwetvedwg sitgtnnrsv tvdggitrtm
      961 lvddtstqwg vpgvpdthla iqywrdplvv ntattptavt vtfqrdiqpt gadysasitv
     1021 tgptgptaga tteptpgali wtpatplppg sytltvdqvs stgpggvpir kpytstftvp
//