LOCUS       XP_008414578             956 aa            linear   VRT 24-MAR-2026
DEFINITION  KIT proto-oncogene, receptor tyrosine kinase b isoform X2 [Poecilia
            reticulata].
ACCESSION   XP_008414578
VERSION     XP_008414578.1
DBLINK      BioProject: PRJNA1116237
DBSOURCE    REFSEQ: accession XM_008416356.3
KEYWORDS    RefSeq.
SOURCE      Poecilia reticulata (guppy)
  ORGANISM  Poecilia reticulata
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes;
            Poeciliidae; Poeciliinae; Poecilia.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_088830) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_904066995.2-RS_2026_03
            Annotation Pipeline         :: NCBI Eukaryotic Genome Annotation
                                           Pipeline (EGAP)
            Annotation Software Version :: 10.5
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 03/18/2026
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..956
                     /organism="Poecilia reticulata"
                     /db_xref="taxon:8081"
                     /chromosome="1"
     Protein         1..956
                     /product="KIT proto-oncogene, receptor tyrosine kinase b
                     isoform X2"
                     /calculated_mol_wt=107430
     Region          30..109
                     /region_name="IG_like"
                     /note="Immunoglobulin like; smart00410"
                     /db_xref="CDD:214653"
     Region          220..305
                     /region_name="ig"
                     /note="Immunoglobulin domain; pfam00047"
                     /db_xref="CDD:395002"
     Region          229..233
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          243..247
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          273..277
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          287..292
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          311..413
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          331..335
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          345..349
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          377..381
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          391..396
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          404..407
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     Region          553..900
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(595..598,601,603,621,623,654,670..673,767,771..772,
                     774,784..785)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270682"
     CDS             1..956
                     /gene="kitb"
                     /coded_by="XM_008416356.3:225..3095"
                     /db_xref="GeneID:103468941"
ORIGIN      
        1 mrcpwvicas yfiflpitaw skpvifpsep hivvpkkgkl qlrchdnatv sgapfllrwh
       61 reknrklege veegkvaslt lsgvqaqqmg wyvcvnnhtq enssifvyvk dphsafqqtm
      121 mssilvrage dciipclvtd pevanlslet cdgrplpsgm vyrgnlqrgi iirnarekik
      181 gcyrcvgqld gnrvtsvpys vdvrpvpelr pevilshkdt vilktgeafe ltcnstnins
      241 efsltwdfps aanpvksqis hilpssrgyl rsttlsiatv gqldsgiyrc hahnekghsd
      301 aamqldvrgq gfitplgnhs piqevkeges ltlwvefday paprsifwsy nkehllntte
      361 hvitvravkh rkyrftsqlr lvrvlssegg vytfsvsngd asvdrsfhvy vnskpviiaq
      421 dgpvdgqvrc iaagypvpki swyfcelprt rcsnlpnatq wespevtvls esafgrseve
      481 srlnvsneha qyhtlecvas tqgeeaytlf tirerivphk lftplltgml atgvflsvil
      541 vvlfykymqk pkfqiqwkvi esingnnyiy idplqlpydl kwefprqklr fgktlgsgaf
      601 gkvvratayg lcsadtvttv avkmlkpnah stekealmse lkvlsylgnh vnivnllgac
      661 tvggpilvit eyccygdlln flrrkresfl nsqvgdgyyr nvskqseptr daigtgyipm
      721 rpsekerssq sdyidelsld aedllsfsyq vakgmeyits kncihrdlaa rnvllthgrv
      781 akicdfglar dittdssyvl rgnarlpvkw mspesifdcv ytfesdvwsy gillweifsl
      841 gnspypgmqv gsafykmiqd grrmnrpefa piemydmmls cwnddplkrp sfrklverte
      901 lllsentknv yltlsnapna seqqrapsrr lssvcsttap tqpllqnavd vfldyv
//