LOCUS XP_011840757 1106 aa linear PRI 30-MAR-2015
DEFINITION PREDICTED: platelet-derived growth factor receptor beta isoform X1
[Mandrillus leucophaeus].
ACCESSION XP_011840757
VERSION XP_011840757.1
DBLINK BioProject: PRJNA279492
DBSOURCE REFSEQ: accession XM_011985367.1
KEYWORDS RefSeq.
SOURCE Mandrillus leucophaeus (drill)
ORGANISM Mandrillus leucophaeus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Cercopithecidae; Cercopithecinae; Mandrillus.
COMMENT MODEL REFSEQ: This record is predicted by automated computational
analysis. This record is derived from a genomic sequence
(NW_012102943.1) annotated using gene prediction method: Gnomon,
supported by mRNA and EST evidence.
Also see:
Documentation of NCBI's Annotation Process
##Genome-Annotation-Data-START##
Annotation Provider :: NCBI
Annotation Status :: Full annotation
Annotation Version :: Mandrillus leucophaeus Annotation
Release 100
Annotation Pipeline :: NCBI eukaryotic genome annotation
pipeline
Annotation Software Version :: 6.2
Annotation Method :: Best-placed RefSeq; Gnomon
Features Annotated :: Gene; mRNA; CDS; ncRNA
##Genome-Annotation-Data-END##
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..1106
/organism="Mandrillus leucophaeus"
/isolate="KB7577"
/db_xref="taxon:9568"
/chromosome="Unknown"
/sex="female"
/tissue_type="heart"
Protein 1..1106
/product="platelet-derived growth factor receptor beta
isoform X1"
/calculated_mol_wt=124046
Region 37..114
/region_name="ig"
/note="Immunoglobulin domain; pfam00047"
/db_xref="CDD:395002"
Region 50..54
/region_name="Ig strand B"
/note="Ig strand B [structural motif]"
/db_xref="CDD:409353"
Region 60..63
/region_name="Ig strand C"
/note="Ig strand C [structural motif]"
/db_xref="CDD:409353"
Region 83..87
/region_name="Ig strand E"
/note="Ig strand E [structural motif]"
/db_xref="CDD:409353"
Region 97..101
/region_name="Ig strand F"
/note="Ig strand F [structural motif]"
/db_xref="CDD:409353"
Region 212..311
/region_name="IgI_PDGFR-alphabeta"
/note="Immunoglobulin (Ig)-like domain of platelet-derived
growth factor (PDGF) receptors (R), alpha and beta; member
of the I-set of IgSF domains; cd05861"
/db_xref="CDD:409447"
Region 212..216
/region_name="Ig strand A"
/note="Ig strand A [structural motif]"
/db_xref="CDD:409447"
Region 223..227
/region_name="Ig strand A'"
/note="Ig strand A' [structural motif]"
/db_xref="CDD:409447"
Region 229..238
/region_name="Ig strand B"
/note="Ig strand B [structural motif]"
/db_xref="CDD:409447"
Region 243..248
/region_name="Ig strand C"
/note="Ig strand C [structural motif]"
/db_xref="CDD:409447"
Region 251..253
/region_name="Ig strand C'"
/note="Ig strand C' [structural motif]"
/db_xref="CDD:409447"
Region 257..265
/region_name="Ig strand D"
/note="Ig strand D [structural motif]"
/db_xref="CDD:409447"
Region 270..278
/region_name="Ig strand E"
/note="Ig strand E [structural motif]"
/db_xref="CDD:409447"
Region 288..294
/region_name="Ig strand F"
/note="Ig strand F [structural motif]"
/db_xref="CDD:409447"
Region 299..305
/region_name="Ig strand G"
/note="Ig strand G [structural motif]"
/db_xref="CDD:409447"
Region 314..415
/region_name="Ig4_PDGFR"
/note="Fourth immunoglobulin (Ig)-like domain of
platelet-derived growth factor receptor (PDGFR); cd05859"
/db_xref="CDD:409445"
Region 431..519
/region_name="Ig"
/note="Immunoglobulin domain; cl11960"
/db_xref="CDD:472250"
Region 432..436
/region_name="Ig strand B"
/note="Ig strand B [structural motif]"
/db_xref="CDD:143277"
Region 445..449
/region_name="Ig strand C"
/note="Ig strand C [structural motif]"
/db_xref="CDD:143277"
Region 493..497
/region_name="Ig strand E"
/note="Ig strand E [structural motif]"
/db_xref="CDD:143277"
Region 504..510
/region_name="Ig strand F"
/note="Ig strand F [structural motif]"
/db_xref="CDD:143277"
Region 562..953
/region_name="PTKc_PDGFR_beta"
/note="Catalytic domain of the Protein Tyrosine Kinase,
Platelet Derived Growth Factor Receptor beta; cd05107"
/db_xref="CDD:133238"
Site order(606..607,609..612,614,632,634,682,684,688,826,
830..831,833,844,862..866,875,910)
/site_type="active"
/db_xref="CDD:133238"
Site order(606..607,609..612,614,632,634,682,684,688,830..831,
833,844)
/site_type="other"
/note="ATP binding site [chemical binding]"
/db_xref="CDD:133238"
Site order(826,830,862..866,875,910)
/site_type="other"
/note="polypeptide substrate binding site [polypeptide
binding]"
/db_xref="CDD:133238"
Site 843..868
/site_type="other"
/note="activation loop (A-loop)"
/db_xref="CDD:133238"
CDS 1..1106
/gene="PDGFRB"
/coded_by="XM_011985367.1:39..3359"
/db_xref="GeneID:105543434"
ORIGIN
1 mrlpgampal alkgqllllp lllllkpqvs qglvitppgp elilnvsstf vltcsgsapv
61 mwermsqelp qemakaqdnt fssvltltnl tgldtgeyfc tyndsrglep derkrlyifv
121 pdptvgflpn daeelfiflt eiteitipcr vtdpqlvvtl hekkgdialp vpydhqrgfs
181 gifedrsyic kttigdrevd sdayyvyrlq vssinvsvna vqtvvrqgen itlmcivign
241 evvnfewtyp rkesgrlvep vtdflldmpy hirsilhips aeledsgtyt cnvtesvndh
301 qdekainitv vesgyvrllg evgalqfael hrsrtlqvvf eayppptvlw fkdnrtlgds
361 sageialstr nvsetryvse ltlvrvkvae aghytmrafh edaevqlsfq lqinvpvrvl
421 elseshpdsg eqtvrcrgrg mpqpniiwsa crdlkrcpre lppmllgnss eeesqletnv
481 tyweeeqefe vvstlrlqhv drplsvrctl rnavgqdmqe vivvphslpf kavvisaila
541 lvvltiisli ilimlwqkkp ryeirwkvie svssdgheyi yvdpmqlpyd stwelprdql
601 vlgrtlgsga fgqvveatah glshsqatmk vavkmlksta rssekqalms elkimshlgp
661 hlnvvnllga ctkggpiyii teycrygdlv dylhrnkhtf lqhhsdkrrp psaelysnal
721 pvglplpshv sltgesdggy mdmskdesvd yvpmldmkgd vkyadiessn ymapydnyvp
781 sapertcrat linespvlsy mdlvgfsyqv angmeflask ncvhrdlaar nvlicegklv
841 kicdfglard imrdsnyisk gstflplkwm apesifnsly ttlsdvwsfg illweiftlg
901 gtpypelpmn eqfynaikrg yrmaqpahas deiyeimqkc weekfeirpp fsqlvlller
961 llgegykkky qqvdeeflrs dhpailrsqa rlpgfhglrs pldsssvlyt avqpnegdnd
1021 yiiplpdpkp evadegpleg spslasstln evntsstisc dsplepqeep epepqlerqv
1081 epepeleqlp dsgcpaprae aedsfl
//
