LOCUS XP_013922176 480 aa linear VRT 11-SEP-2015
DEFINITION PREDICTED: retinoic acid receptor RXR-alpha isoform X1 [Thamnophis
sirtalis].
ACCESSION XP_013922176
VERSION XP_013922176.1
DBLINK BioProject: PRJNA294278
DBSOURCE REFSEQ: accession XM_014066701.1
KEYWORDS RefSeq.
SOURCE Thamnophis sirtalis
ORGANISM Thamnophis sirtalis
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata;
Toxicofera; Serpentes; Colubroidea; Colubridae; Natricinae;
Thamnophis.
COMMENT MODEL REFSEQ: This record is predicted by automated computational
analysis. This record is derived from a genomic sequence
(NW_013658945.1) annotated using gene prediction method: Gnomon.
Also see:
Documentation of NCBI's Annotation Process
##Genome-Annotation-Data-START##
Annotation Provider :: NCBI
Annotation Status :: Full annotation
Annotation Version :: Thamnophis sirtalis Annotation
Release 100
Annotation Pipeline :: NCBI eukaryotic genome annotation
pipeline
Annotation Software Version :: 6.4
Annotation Method :: Best-placed RefSeq; Gnomon
Features Annotated :: Gene; mRNA; CDS; ncRNA
##Genome-Annotation-Data-END##
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..480
/organism="Thamnophis sirtalis"
/isolate="EDBJR-23777"
/specimen_voucher="UTA:R:62823"
/db_xref="taxon:35019"
/chromosome="Unknown"
/sex="female"
/tissue_type="skeletal muscle"
/dev_stage="adult"
/geo_loc_name="USA: Coffin Butte Rd., Benton Co., Oregon"
/lat_lon="44.6992 N 123.2217 W"
/collection_date="Jun-2010"
/collected_by="Brian Gall"
Protein 1..480
/product="retinoic acid receptor RXR-alpha isoform X1"
/calculated_mol_wt=52668
Region 18..126
/region_name="Nuc_recep-AF1"
/note="Nuclear/hormone receptor activator site AF-1;
pfam11825"
/db_xref="CDD:463363"
Region 132..227
/region_name="NR_DBD_RXR"
/note="DNA-binding domain of retinoid X receptor (RXR) is
composed of two C4-type zinc fingers; cd06956"
/db_xref="CDD:143514"
Site order(134,137,151,154,170,176,186,189)
/site_type="other"
/note="zinc binding site [ion binding]"
/db_xref="CDD:143514"
Site order(139,180..181,183,185)
/site_type="other"
/note="RXR/ECR heterodimer interface [polypeptide
binding]"
/db_xref="CDD:143514"
Site order(143..146,152..153,155,157,159..160,163,171,183..184,
187,190,222..224,226..227)
/site_type="DNA binding"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:143514"
Site order(165,188,191..192,195..196,200..202,225..227)
/site_type="other"
/note="RXR/PPAR heterodimer interface [polypeptide
binding]"
/db_xref="CDD:143514"
Site order(181..182,185)
/site_type="other"
/note="RXR/RXR homodimer interface DR1 [polypeptide
binding]"
/db_xref="CDD:143514"
Site order(202,222..226)
/site_type="other"
/note="RXR/RXR homodimer interface DR2 [polypeptide
binding]"
/db_xref="CDD:143514"
Site order(225,227)
/site_type="other"
/note="RXR/RAR heterodimer interface [polypeptide
binding]"
/db_xref="CDD:143514"
Region 247..458
/region_name="NR_LBD_RXR_like"
/note="The ligand binding domain of the retinoid X
receptor and Ultraspiracle, members of nuclear receptor
superfamily; cd06943"
/db_xref="CDD:132741"
Site order(286..287,289..290,293,327,331,334,344..345,360,450,
453..454)
/site_type="other"
/note="ligand binding site [chemical binding]"
/db_xref="CDD:132741"
Site order(295,298,302,307,312..313,315..316,320)
/site_type="other"
/note="coactivator recognition site [polypeptide binding]"
/db_xref="CDD:132741"
Site order(366,370,374,391,397,411..412,415..416,419,433..434,
437..438,440..442,444..445,448,452)
/site_type="other"
/note="heterodimer interface [polypeptide binding]"
/db_xref="CDD:132741"
Site order(366,370,374,397,399,408,415,419,431,434..435,
438..441,444..445,448,452)
/site_type="other"
/note="homodimer interface [polypeptide binding]"
/db_xref="CDD:132741"
CDS 1..480
/gene="RXRA"
/coded_by="XM_014066701.1:214..1656"
/db_xref="GeneID:106549135"
ORIGIN
1 mdtkhflpld fsaqvnstsl ssptgrgshm gtpalhpsmg pslggslgsp sqlhspingm
61 gppfsvissp mgphamsgps tpglgygags pqlnsplnpv sstedikppl gingvlkvpm
121 hpssampaft khicaicgdr ssgkhygvys cegckgffkr tvrkdlsytc rdnkdclidk
181 rqrnrcqycr yqkclamgmk regmehhpsr ptrlpgrqeq pavqeerqrg kdrneneves
241 tsnanedmpv ekileaelav epktetyiea nmglapnspn dpvtnicqaa dkqlftlvew
301 akriphfsel plddqvillr agwnellias fshrsiavkd gillatglhv hrnsahsagv
361 gaifdrvlte lvskmrdmqm dktelgclra ivlfnpdskg lsnpaeveal rekvyaslea
421 yckqkypeqp grfaklllrl palrsiglkc lehlfffkli gdtpidtflm emleaphqmt
//
