LOCUS       XP_017667216             537 aa            linear   VRT 11-AUG-2016
DEFINITION  PREDICTED: suppressor of cytokine signaling 5 [Lepidothrix
            coronata].
ACCESSION   XP_017667216
VERSION     XP_017667216.1
DBLINK      BioProject: PRJNA338288
DBSOURCE    REFSEQ: accession XM_017811727.1
KEYWORDS    RefSeq.
SOURCE      Lepidothrix coronata (blue-crowned manakin)
  ORGANISM  Lepidothrix coronata
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
            Passeriformes; Pipridae; Lepidothrix.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_016690213.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Version          :: Lepidothrix coronata Annotation
                                           Release 100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 7.1
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..537
                     /organism="Lepidothrix coronata"
                     /isolate="B3197"
                     /specimen_voucher="LSUMZ:110521"
                     /db_xref="taxon:321398"
                     /chromosome="Unknown"
                     /sex="male"
                     /dev_stage="adult"
                     /geo_loc_name="Peru: Loreto Department, 1.5 km S Libertad,
                     S. bank Rio Napo, 80 km N Iquitos"
     Protein         1..537
                     /product="suppressor of cytokine signaling 5"
                     /calculated_mol_wt=61353
     Region          146..196
                     /region_name="SOCS"
                     /note="Suppressor of cytokine signalling; pfam12610"
                     /db_xref="CDD:432667"
     Region          371..471
                     /region_name="SH2"
                     /note="Src homology 2 (SH2) domain; cl15255"
                     /db_xref="CDD:472789"
     Site            order(389,407,428,430)
                     /site_type="other"
                     /note="phosphotyrosine binding pocket [polypeptide
                     binding]"
                     /db_xref="CDD:198173"
     Site            order(429,459)
                     /site_type="other"
                     /note="hydrophobic binding pocket [polypeptide binding]"
                     /db_xref="CDD:198173"
     Region          480..536
                     /region_name="SOCS_SOCS5"
                     /note="SOCS (suppressors of cytokine signaling) box of
                     SOCS5-like proteins. Together with CIS1, the CIS/SOCS
                     family of proteins is characterized by the presence of a
                     C-terminal SOCS box and a central SH2 domain. SOCS5
                     inhibits Th2 differentiation by inhibiting...; cd03739"
                     /db_xref="CDD:239708"
     Site            order(481..486,492,499,505,510)
                     /site_type="other"
                     /note="putative elongin B/C interaction [polypeptide
                     binding]"
                     /db_xref="CDD:239708"
     CDS             1..537
                     /gene="SOCS5"
                     /coded_by="XM_017811727.1:517..2130"
                     /db_xref="GeneID:108495721"
ORIGIN      
        1 mdkvgkmwnn fkyrcqnlfs heggsqneni ivnssncssa kekaiqvtdl tqqqppsspl
       61 renialqlgl spsknsarrn qncvteipqi veisiekend scvttgarla rrdsysrhap
      121 wggkkkhscs tktqssldte krfgrtrsgl qrrerrygvs svhdmdavss rtvgsrslrq
      181 rlqdtvglcf pmrtyskqsk plfsnkrkih lselmlekcp fpagsdlaqk whlikqhtap
      241 vsphstffdt fdpslvsted eedrlrerrr lsieegvdpp pnaqihtfea taqvnplykl
      301 gpklapgmte ltgdktitpp gncdseedtt tlclqsrrqk qrqmsgeshg hisrqgawkv
      361 htqidyihcl vpdllqitgn pcywgvmdry eaeallegkp egtfllrdsa qedylfsvsf
      421 rrynrslhar ieqwnhnfsf dahdpcvfhs stvtgllehy kdpsscmffe plltvslnrt
      481 fpfslqyicr avicrcttyd giddlplpsm lqdflkeyhy kqkvrvrwle repiktk
//